NMR/MRI Animal Imaging Lab
Diana Lindquist, PhD
This mouse imaging system and laboratory is own by the UC College of Medicine but is currently staffed and administered by experienced imaging personnel from Cincinnati Children's Hospital Medical Center. The laboratory includes a fully equipped chemistry lab complete with fume hood as well as a Bruker 9.4T (400 MHz) vertical wide-bore system.
This system is capable of conventional high-resolution multinuclear NMR acquisitions, including z-gradient experiments, as well as magic-angle spinning 1H and 13C acquisitions of tissue samples.
A gradient insert and special microimaging coils allow for 1H, 23Na, 7Li, 31P, or 13C MR imaging or spectroscopy acquisitions from mice and very small rats. The system is based on Bruker AVIII HD hardware.
Types of analyses available include:
- 400 MHz high-resolution NMR of extracts
- 400 MHz magic angle spinning
- Small animal imaging (mice and rats smaller than 150 g)
- In vivo magnetic resonance spectroscopy of 1H, 31P, and 13C
The core is located in Medical Sciences Building Room 4106. The Director is available by appointment.
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