C. Ralph Buncher

C. Ralph Ralph Buncher


Kettering Lab Complex


COM EH Epi-Bio Division - 0056


BS, Massachusetts Institute of Technology Cambridge, MA, 1960 (Industrial Management and Biostatistics)

MS, Harvard University Boston, MA, 1964 (Biostatistics and Epidemiology)

Sc.D., Harvard University Boston, MA, 1967 (Biostatistics and Epidemiology)

Research Support

Grant: #U01-CA96109 Investigators:Buncher, Charles 09-17-2002 -08-31-2008 National Cancer Institute Phase II Trial of ACAPHA in Former Smokers with IEN Role:PI $133,102.00 Closed Level:Federal

Grant: #AK-01-01-A0-S2-E3 Investigators:Buncher, Charles 01-01-1997 -09-30-2000 AK Steel Corporation AK Steel Mortality Report Role:PI $84,233.00 Closed Level:Industry

Grant: #66636 Investigators:Buncher, Charles; Kennerly, Susan; Kim, J.; Miller, Elaine; Yap, Tracey 09-01-2009 -08-31-2011 Robert Wood Johnson Foundation Interdisciplinary Mobility Team Approach to Reduction of Facility-Acquired Pressure Ulcers Role:Collaborator $299,963.00 Active Level:Private Non-Profit

Grant: #103075 / U01 DK072493 Investigators:Buncher, Charles 12-15-2009 -09-22-2011 National Inst of Diabetes and Digestive and Kidney Disease Adolescent Bariatrics: Assessing Health Benefits and Risks Role:PI $244,471.00 Closed Level:Federal

Grant: #DK095710 Investigators:Buncher, Charles 09-23-2011 -08-31-2016 National Inst of Diabetes and Digestive and Kidney Disease Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Role:PI $1,674,106.00 Active Level:Federal


Peer Reviewed Publications

Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Helmrath, Michael A; Brandt, Mary L; Harmon, Carroll M; Zeller, Meg H; Chen, Mike K; Xanthakos, Stavra A; Horlick, Mary; Buncher, C Ralph (2016. ) Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents.The New England journal of medicine, , 374 (2 ) ,113-23

Yap, Tracey L; Kennerly, Susan M; Simmons, Mark R; Buncher, Charles R; Miller, Elaine; Kim, Jay; Yap, Winston Y (2013. ) Multidimensional team-based intervention using musical cues to reduce odds of facility-acquired pressure ulcers in long-term care: a paired randomized intervention study.Journal of the American Geriatrics Society, , 61 (9 ) ,1552-9

Jenkins, Todd M; Buncher, C Ralph; Akers, Rachel; Daniels, Stephen R; Lawson, M Louise; Khoury, Philip R; Wilson, Tawny P; Inge, Thomas H (2013. ) Validation of a weight history questionnaire to identify adolescent obesity.Obesity surgery, , 23 (9 ) ,1404-12

Rice, Carol; Jin, Na; Cocco, P; Dosemeci, M; Buncher, C R The exposure metric: does including time since exposure in the calculation of working lifetime exposure provide a better understanding of disease risk than the cumulative exposure? .La Medicina del lavoro, , 102 (4 ) ,343-9

Shire, Norah J; Rao, Marepalli B; Succop, Paul; Buncher, C Ralph; Andersen, Janet A; Butt, Adeel A; Chung, Raymond T; Sherman, Kenneth E (2009. ) Improving noninvasive methods of assessing liver fibrosis in patients with hepatitis C virus/human immunodeficiency virus co-infection.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, , 7 (4 ) ,471-80, 480.e1-2

Anderson, Marshall W; Goodin, Colleen; Zhang, Yu; Kim, Sangmi; Estensen, Richard D; Wiedmann, Timothy S; Sekar, Padmini; Buncher, C Ralph; Khoury, Jane C; Garbow, Joel R; You, Ming; Tichelaar, Jay W (2008. ) Effect of dietary green tea extract and aerosolized difluoromethylornithine during lung tumor progression in A/J strain mice.Carcinogenesis, , 29 (8 ) ,1594-600

Bedard, Angela C; Huether, Carl A; Shooner, Kerry; Buncher, C Ralph; Warren, Nancy Steinberg (2007. ) Career research interests and training of genetic counseling students.Journal of genetic counseling, , 16 (5 ) ,645-53

Comstock, C E S; Revelo, M P; Buncher, C R; Knudsen, K E (2007. ) Impact of differential cyclin D1 expression and localisation in prostate cancer.British journal of cancer, , 96 (6 ) ,970-9

Wetherill, Yelena B; Hess-Wilson, Janet K; Comstock, Clay E S; Shah, Supriya A; Buncher, C Ralph; Sallans, Larry; Limbach, Patrick A; Schwemberger, Sandy; Babcock, George F; Knudsen, Karen E (2006. ) Bisphenol A facilitates bypass of androgen ablation therapy in prostate cancer.Molecular cancer therapeutics, , 5 (12 ) ,3181-90

Clark, Heather M; Gamm, Jennifer; Huether, Carl A; Buncher, C Ralph; Pfau, Ruthann I Blough; Warren, Nancy Steinberg (2006. ) Genetic counselors and research: current practices and future directions.American journal of medical genetics. Part C, Seminars in medical genetics, , 142C (4 ) ,276-83

Gilbert, Donald L; Buncher, C Ralph (2006. ) Epileptiform discharges and the behavior of children with epilepsy.The Journal of pediatrics, , 149 (2 ) ,283; author reply 28

Gilbert, Donald L; Buncher, C Ralph (2005. ) Assessment of scientific and ethical issues in two randomized clinical trial designs for patients with Tourette's syndrome: a model for studies of multiple neuropsychiatric diagnoses.The Journal of neuropsychiatry and clinical neurosciences, , 17 (3 ) ,324-32

Khoury, J C; Miodovnik, M; Buncher, C R; Kalkwarf, H; McElvy, S; Khoury, P R; Sibai, B (2004. ) Consequences of smoking and caffeine consumption during pregnancy in women with type 1 diabetes.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, , 15 (1 ) ,44-50

Gilbert, Donald L; Sethuraman, Gopalan; Kotagal, Uma; Buncher, C Ralph (2003. ) Meta-analysis of EEG test performance shows wide variation among studies. Neurology, , 60 (4 ) ,564-70

Jazieh, Abdul R; Buncher, Charles R (2002. ) Racial and age-related disparities in obtaining screening mammography: results of a statewide database. Southern medical journal, , 95 (10 ) ,1145-8

Pomerantz, W J; Dowd, M D; Buncher, C R (2001. ) Relationship between socioeconomic factors and severe childhood injuries.Journal of urban health : bulletin of the New York Academy of Medicine, , 78 (1 ) ,141-51

Gilbert, D L; Buncher, C R (2000. ) An EEG should not be obtained routinely after first unprovoked seizure in childhood. Neurology, , 54 (3 ) ,635-41

Iannaccone, S T; Russman, B S; Browne, R H; Buncher, C R; White, M; Samaha, F J (2000. ) Prospective analysis of strength in spinal muscular atrophy. DCN/Spinal Muscular Atrophy Group. Journal of child neurology, , 15 (2 ) ,97-101

Buncher, C R; Morrison, J A (1998. ) Those confounding variables! .The Journal of pediatrics, , 133 (2 ) ,174-5

Linz, D H; Pinney, S M; Keller, J D; White, M; Buncher, C R (1998. ) Cluster analysis applied to building-related illness. Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine, , 40 (2 ) ,165-71

Kuempel, E D; Stayner, L T; Attfield, M D; Buncher, C R (1996. ) Possible misclassification did not obscure detection of exposure-response.American journal of industrial medicine, , 30 (5 ) ,643-4

Russman, B S; Buncher, C R; White, M; Samaha, F J; Iannaccone, S T (1996. ) Function changes in spinal muscular atrophy II and III. The DCN/SMA Group. Neurology, , 47 (4 ) ,973-6

Creticos, P S; Reed, C E; Norman, P S; Khoury, J; Adkinson, N F; Buncher, C R; Busse, W W; Bush, R K; Gadde, J; Li, J T (1996. ) Ragweed immunotherapy in adult asthma.The New England journal of medicine, , 334 (8 ) ,501-6

Taha, J M; Tew, J M; Buncher, C R (1995. ) A prospective 15-year follow up of 154 consecutive patients with trigeminal neuralgia treated by percutaneous stereotactic radiofrequency thermal rhizotomy.Journal of neurosurgery, , 83 (6 ) ,989-93

Leikauf, G D; Kline, S; Albert, R E; Baxter, C S; Bernstein, D I; Bernstein, J; Buncher, C R (1995. ) Evaluation of a possible association of urban air toxics and asthma. Environmental health perspectives, , 103 Suppl 6 ,253-71

Kuempel, E D; Stayner, L T; Attfield, M D; Buncher, C R (1995. ) Exposure-response analysis of mortality among coal miners in the United States. American journal of industrial medicine, , 28 (2 ) ,167-84

Tian, J J; Shukla, R; Buncher, C R (1994. ) On prediction of future observation in growth curve model. Statistics in medicine, , 13 (21 ) ,2205-17

Samaha, F J; Buncher, C R; Russman, B S; White, M L; Iannaccone, S T; Barker, L; Burhans, K; Smith, C; Perkins, B; Zimmerman, L (1994. ) Pulmonary function in spinal muscular atrophy. Journal of child neurology, , 9 (3 ) ,326-9

Betemps, E J; Buncher, C R; Clark, C S (1994. ) Proportional mortality analysis of wastewater treatment system workers by birthplace with comments on amyotrophic lateral sclerosis. Journal of occupational medicine. : official publication of the Industrial Medical Association, , 36 (1 ) ,31-5

Pavelic, Z P; Portugal, L G; Gootee, M J; Stambrook, P J; Smith, C; Mugge, R E; Pavelic, L; Wilson, K; Buncher, C R; Li, Y Q (1993. ) Retrieval of p53 protein in paraffin-embedded head and neck tumor tissues. Archives of otolaryngology--head & neck surgery, , 119 (11 ) ,1206-9

Betemps, E J; Buncher, C R (1993. ) Birthplace as a risk factor in motor neurone disease and Parkinson's disease. International journal of epidemiology, , 22 (5 ) ,898-904

Iannaccone, S T; Browne, R H; Samaha, F J; Buncher, C R Prospective study of spinal muscular atrophy before age 6 years. DCN/SMA Group. Pediatric neurology, , 9 (3 ) ,187-93

Betemps, E J; Somoza, E; Buncher, C R (1993. ) Hospital characteristics, diagnoses, and staff reasons associated with use of seclusion and restraint. Hospital & community psychiatry, , 44 (4 ) ,367-71

Russman, B S; Iannacone, S T; Buncher, C R; Samaha, F J; White, M; Perkins, B; Zimmerman, L; Smith, C; Burhans, K; Barker, L (1992. ) Spinal muscular atrophy: new thoughts on the pathogenesis and classification schema. Journal of child neurology, , 7 (4 ) ,347-53

Betemps, E J; Buncher, C R; Oden, M (1992. ) Length of time spent in seclusion and restraint by patients at 82 VA medical centers. Hospital & community psychiatry, , 43 (9 ) ,912-4

Lanphear, B P; Buncher, C R (1992. ) Latent period for malignant mesothelioma of occupational origin. Journal of occupational medicine. : official publication of the Industrial Medical Association, , 34 (7 ) ,718-21

Buncher, C R; Collins, J J; Halperin, W (1991. ) Possible progress and unresolved conflicts resulting from guidelines on good epidemiologic practices. Journal of occupational medicine. : official publication of the Industrial Medical Association, , 33 (12 ) ,1261-4

Collins, J J; Buncher, C R; Halperin, W (1991. ) Managing the quality and conduct of epidemiologic studies. Journal of occupational medicine. : official publication of the Industrial Medical Association, , 33 (12 ) ,1213-5

Foulkes, E C; Mort, T L; Buncher, C R (1991. ) Intestinal cadmium permeability in mature and immature rats. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , 197 (4 ) ,477-81

Denman, D L; Legorreta, R A; Kier, A B; Elson, H R; White, M L; Buncher, C R; Lewis, G C; Born, A M; Sundararaman, S; Aron, B S (1991. ) Therapeutic responses of spontaneous canine malignancies to combinations of radiotherapy and hyperthermia. International journal of radiation oncology, biology, physics, , 21 (2 ) ,415-22

Buncher, C R; Succop, P A; Dietrich, K N (1991. ) Structural equation modeling in environmental risk assessment. Environmental health perspectives, , 90 ,209-13

Dietrich, K N; Succop, P A; Bornschein, R L; Krafft, K M; Berger, O; Hammond, P B; Buncher, C R (1990. ) Lead exposure and neurobehavioral development in later infancy. Environmental health perspectives, , 89 ,13-9

Buncher, C R; Samaha, F; Iannaccone, S T; Russman, B S; Cook, J D; White, M; McLaughlin, C (1990. ) Statistical considerations in the study of spinal muscular atrophy. Dallas-Cincinnati-Newington Spinal Muscular Atrophy (DCN-SMA) Study Group. Muscle & nerve, , 13 Suppl ,S45-8

Buncher, C R (1989. ) Did formaldehyde cause lung cancer? .Journal of occupational medicine. : official publication of the Industrial Medical Association, , 31 (11 ) ,885

Shukla, R; Bornschein, R L; Dietrich, K N; Buncher, C R; Berger, O G; Hammond, P B; Succop, P A (1989. ) Fetal and infant lead exposure: effects on growth in stature. Pediatrics, , 84 (4 ) ,604-12

Fowler, N O; Gabel, M; Buncher, C R (1988. ) Cardiac tamponade: a comparison of right versus left heart compression. Journal of the American College of Cardiology, , 12 (1 ) ,187-93

Buncher, C R (1988. ) Statistics in sports injury research. The American journal of sports medicine, , 16 Suppl 1 ,S57-62

Keller, C S; Noyes, F R; Buncher, C R (1988. ) The medical aspects of soccer injury epidemiology. The American journal of sports medicine, , 16 Suppl 1 ,S105-12

Kaufman, R A; Carroll, C D; Buncher, C R Atlantooccipital junction: standards for measurement in normal children. AJNR. American journal of neuroradiology, , 8 (6 ) ,995-9

Specker, B L; Saenger, E L; Buncher, C R; McDevitt, R A (1987. ) Pulmonary embolism and lung scanning: cost-effectiveness and benefit:risk. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, , 28 (10 ) ,1521-30

Keller, C S; Noyes, F R; Buncher, C R The medical aspects of soccer injury epidemiology. The American journal of sports medicine, , 15 (3 ) ,230-7

Saenger, E L; Buncher, C R; Specker, B L; McDevitt, R A (1985. ) Determination of clinical efficacy: nuclear medicine as applied to lung scanning. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, , 26 (7 ) ,793-806

Bonventre, P F; Linnemann, C; Weckbach, L S; Staneck, J L; Buncher, C R; Vigdorth, E; Ritz, H; Archer, D; Smith, B (1984. ) Antibody responses to toxic-shock-syndrome (TSS) toxin by patients with TSS and by healthy staphylococcal carriers. The Journal of infectious diseases, , 150 (5 ) ,662-6

Berlin, N I; Buncher, C R; Fontana, R S; Frost, J K; Melamed, M R (1984. ) The National Cancer Institute Cooperative Early Lung Cancer Detection Program. Results of the initial screen (prevalence). Early lung cancer detection: Introduction.The American review of respiratory disease, , 130 (4 ) ,545-9

Linnemann, C C; Staneck, J L; Hornstein, S; Barden, T P; Rauh, J L; Bonventre, P F; Buncher, C R; Beiting, A (1982. ) The epidemiology of genital colonization with Staphylococcus aureus. Annals of internal medicine, , 96 (6 Pt 2 ) ,940-4

Gartside, P S; Buncher, C R; Lerner, S (1982. ) Relationship of air lead and blood lead for workers at an automobile battery factory. International archives of occupational and environmental health, , 50 (1 ) ,1-10

Maxon, H R; Saenger, E L; Buncher, C R; Thomas, S R; Kereiakes, J G; Shafer, M L; McLaughlin, C A Radiation-associated carcinoma of the salivary glands. A controlled study. The Annals of otology, rhinology, and laryngology, , 90 (2 Pt 1 ) ,107-8

Emmett, E A; Buncher, C R; Suskind, R B; Rowe, K W (1981. ) Skin and eye diseases among arc welders those exposed to welding operations. Journal of occupational medicine. : official publication of the Industrial Medical Association, , 23 (2 ) ,85-90

Elia, V J; Anderson, L A; Macdonald, T J; Carson, A; Buncher, C R; Brooks, S M (1980. ) Determination of urinary mandelic and phenylglyoxylic acids in styrene exposed workers and a control population.American Industrial Hygiene Association journal, , 41 (12 ) ,922-6

Maxon, H R; Saenger, E L; Thomas, S R; Buncher, C R; Kereiakes, J G; Shafer, M L; McLaughlin, C A (1980. ) Clinically important radiation-associated thyroid disease. A controlled study. JAMA, , 244 (16 ) ,1802-5

Buncher, C R (1980. ) National Cancer Institute study: evaluation of computed tomography in the diagnosis of intracranial neoplasms. II. Was randomization necessary?.Radiology, , 136 (3 ) ,651-5

Tsang, R; Abrams, L; Joyce, T H; Buncher, C R; Steichen, J J (1979. ) Ionized Ca in neonates in relation to gestational age. The Journal of pediatrics, , 94 (1 ) ,126-9

Mandybur, T I; Ormsby, I; Buncher, C R (1978. ) Enhanced development of mammary tumors in rats following transplacental and neonatal exposure to ethylnitrosourea. Cancer research, , 38 (10 ) ,3182-5

Maxon, H R; Thomas, S R; Saenger, E L; Buncher, C R; Kereiakes, J G (1977. ) Ionizing irradiation and the induction of clinically significant disease in the human thyroid gland. The American journal of medicine, , 63 (6 ) ,967-78

Buncher, C R (1977. ) The golden fleece award: a control?.Science (New York, N.Y.), , 197 (4308 ) ,1036

Kuzma, R J; Kuzma, C M; Buncher, C R (1977. ) Ohio drinking water source and cancer rates. American journal of public health, , 67 (8 ) ,725-9

Buncher, C R (1977. ) Health records.Science (New York, N.Y.), , 195 (4277 ) ,440

Glueck, C J; Mellies, M J; Srivastava, L; Knowles, H C; Fallat, R W; Tsang, R C; Wacholder, S; Buncher, C R (1977. ) Insulin, obesity, and triglyceride interrelationships in sixteen children with familial hypertriglyceridemia. Pediatric research, , 11 (1 Pt 1 ) ,13-9

Buncher, C R (1976. ) On professor Okun's paper. American journal of public health, , 66 (11 ) ,1108

Linnemann, C C; Levinson, J E; Buncher, C R; Schiff, G M (1975. ) Rubella antibody levels in juvenile rheumatoid arthritis. Annals of the rheumatic diseases, , 34 (4 ) ,354-8

Namboodiri, K K; Elston, R C; Glueck, C J; Fallat, R; Buncher, C R; Tsang, R (1975. ) Bivariate analyses of cholesterol and triglyceride levels in families in which probands have type IIb lipoprotein phenotype. American journal of human genetics, , 27 (4 ) ,454-71

Plank, S J; Buncher, C R (1975. ) Maternal ABO groups and the sex ratio of live births. Human heredity, , 25 (3 ) ,226-33

Lutmer, R F; Parsons, D; Glueck, C J; Morrison, J A; Stewart, L; Brazier, J B; Buncher, C R; Ishikawa, T T (1974. ) Analysis of alpha-lipoprotein cholesterol in 50 microl of plasma. Journal of lipid research, , 15 (6 ) ,611-4

Glueck, C J; Fallat, R W; Tsang, R; Buncher, C R (1974. ) Hyperlipemia in progeny of parents with myocardial infarction before age 50. American journal of diseases of children (1960), , 127 (1 ) ,70-5

Glueck, C J; Fallat, R; Buncher, C R; Tsang, R; Steiner, P (1973. ) Familial combined hyperlipoproteinemia: studies in 91 adults and 95 children from 33 kindreds. Metabolism: clinical and experimental, , 23 (2 ) ,1403-28

Glueck, C J; Tsang, R; Fallat, R; Buncher, C R; Evans, G; Steiner, P (1973. ) Familial hypertriglyceridemia: studies in 130 children and 45 siblings of 36 index cases. Metabolism: clinical and experimental, , 22 (10 ) ,1287-309

Buncher, C R (1973. ) Sounding board "administratively significant".The New England journal of medicine, , 289 (3 ) ,155-6

Tal, C; Raychaudhuri, A; Megel, H; Herberman, R B; Buncher, C R (1973. ) Simplified technique for the T-globulin cancer test. Journal of the National Cancer Institute, , 51 (1 ) ,33-43

Blackwell, B; Bloomfield, S S; Buncher, C R (1972. ) Demonstration to medical students of placebo responses and non-drug factors. Lancet (London, England), , 1 (7763 ) ,1279-82

Sampson, R J; Key, C R; Buncher, C R; Iijima, S (1971. ) Smallest forms of papillary carcinoma of the thyroid. A study of 141 microcarcinomas less than 0.1 cm in greatest dimension. Archives of pathology, , 91 (4 ) ,334-9

Sampson, R J; Key, C R; Buncher, C R; Oka, H; Iijima, S (1970. ) Papillary carcinoma of the thyroid gland. Sizes of 525 tumors found at autopsy in Hiroshima and Nagasaki. Cancer, , 25 (6 ) ,1391-3

Sampson, R J; Oka, H; Key, C R; Buncher, C R; Iijima, S (1970. ) Metastases from occult thyroid carcinoma. An autopsy study from Hiroshima and Nagasaki, Japan. Cancer, , 25 (4 ) ,803-11

Sampson, R J; Key, C R; Buncher, C R; Iijima, S (1969. ) Thyroid carcinoma in Hiroshima and Nagasaki. I. Prevalence of thyroid carcinoma at autopsy. JAMA, , 209 (1 ) ,65-70

Dear, H D; Buncher, C R; Sawayama, T (1969. ) Changes in electrocardiogram and serum potassium values following glucose ingestion. Archives of internal medicine, , 124 (1 ) ,25-8

Buncher, C R (1969. ) Cigarette smoking and duration of pregnancy. American journal of obstetrics and gynecology, , 103 (7 ) ,942-6

Kimura, K; Hiramoto, T; Buncher, C R (1969. ) Gastric xanthelasma. Archives of pathology, , 87 (1 ) ,110-7

Published Books

Buncher et al. (2006. ) Statistics in the Pharmaceutical Industry .Boca Raton, FL , Chapman &Hall/CRC (Co-Editor)


Pharmacoeconomics(MeSH PhrmEco),Pharmacoepidemiology(MeSH PhrmEpi),Diseases(MeSH C),Health Care(MeSH N),Health Care Quality, Access, and Evaluation(MeSH N05),Population Characteristics(MeSH N01),Health Care Economics and Organizations(MeSH N03),Neoplasms(MeSH C04),Environmental Pollutants, Noxae, and Pesticides(MeSH D05),Investigative Techniques(MeSH E05),Education(MeSH I02)