C. Ralph Buncher

C. Ralph Ralph Buncher , ScD, MS

Kettering Lab Complex



BS: Massachusetts Institute of Technology Cambridge, MA, 1960 (Industrial Management and Biostatistics)

MS: Harvard University Boston, MA, 1964 (Biostatistics and Epidemiology)

Sc.D.: Harvard University Boston, MA, 1967 (Biostatistics and Epidemiology)

Research Support

Grant: #U01-CA96109 Investigators:Buncher, Charles 09-17-2002 -08-31-2008 National Cancer Institute Phase II Trial of ACAPHA in Former Smokers with IEN Role:PI $133,102.00 Closed Level:Federal

Grant: #AK-01-01-A0-S2-E3 Investigators:Buncher, Charles 01-01-1997 -09-30-2000 AK Steel Corporation AK Steel Mortality Report Role:PI $84,233.00 Closed Level:Industry

Grant: #66636 Investigators:Buncher, Charles; Kennerly, Susan; Kim, J.; Miller, Elaine; Yap, Tracey 09-01-2009 -08-31-2011 Robert Wood Johnson Foundation Interdisciplinary Mobility Team Approach to Reduction of Facility-Acquired Pressure Ulcers Role:Collaborator $299,963.00 Active Level:Private Non-Profit

Grant: #103075 / U01 DK072493 Investigators:Buncher, Charles 12-15-2009 -09-22-2011 National Inst of Diabetes and Digestive and Kidney Disease Adolescent Bariatrics: Assessing Health Benefits and Risks Role:PI $244,471.00 Closed Level:Federal

Grant: #DK095710 Investigators:Buncher, Charles 09-23-2011 -08-31-2016 National Inst of Diabetes and Digestive and Kidney Disease Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Role:PI $1,674,106.00 Active Level:Federal


Peer Reviewed Publications

Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Helmrath, Michael A; Brandt, Mary L; Harmon, Carroll M; Zeller, Meg H; Chen, Mike K; Xanthakos, Stavra A; Horlick, Mary; Buncher, C Ralph (2016. ) Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents.The New England journal of medicine, , 374 (2 ) ,113-23 More Information

Yap, Tracey L; Kennerly, Susan M; Simmons, Mark R; Buncher, Charles R; Miller, Elaine; Kim, Jay; Yap, Winston Y (2013. ) Multidimensional team-based intervention using musical cues to reduce odds of facility-acquired pressure ulcers in long-term care: a paired randomized intervention study.Journal of the American Geriatrics Society, , 61 (9 ) ,1552-9 More Information

Jenkins, Todd M; Buncher, C Ralph; Akers, Rachel; Daniels, Stephen R; Lawson, M Louise; Khoury, Philip R; Wilson, Tawny P; Inge, Thomas H (2013. ) Validation of a weight history questionnaire to identify adolescent obesity.Obesity surgery, , 23 (9 ) ,1404-12 More Information

Rice, Carol; Jin, Na; Cocco, P; Dosemeci, M; Buncher, C R The exposure metric: does including time since exposure in the calculation of working lifetime exposure provide a better understanding of disease risk than the cumulative exposure? .La Medicina del lavoro, , 102 (4 ) ,343-9

Shire, Norah J; Rao, Marepalli B; Succop, Paul; Buncher, C Ralph; Andersen, Janet A; Butt, Adeel A; Chung, Raymond T; Sherman, Kenneth E (2009. ) Improving noninvasive methods of assessing liver fibrosis in patients with hepatitis C virus/human immunodeficiency virus co-infection.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, , 7 (4 ) ,471-80, 480.e1-2 More Information

Anderson, Marshall W; Goodin, Colleen; Zhang, Yu; Kim, Sangmi; Estensen, Richard D; Wiedmann, Timothy S; Sekar, Padmini; Buncher, C Ralph; Khoury, Jane C; Garbow, Joel R; You, Ming; Tichelaar, Jay W (2008. ) Effect of dietary green tea extract and aerosolized difluoromethylornithine during lung tumor progression in A/J strain mice.Carcinogenesis, , 29 (8 ) ,1594-600 More Information

Bedard, Angela C; Huether, Carl A; Shooner, Kerry; Buncher, C Ralph; Warren, Nancy Steinberg (2007. ) Career research interests and training of genetic counseling students.Journal of genetic counseling, , 16 (5 ) ,645-53 More Information

Comstock, C E S; Revelo, M P; Buncher, C R; Knudsen, K E (2007. ) Impact of differential cyclin D1 expression and localisation in prostate cancer.British journal of cancer, , 96 (6 ) ,970-9 More Information

Wetherill, Yelena B; Hess-Wilson, Janet K; Comstock, Clay E S; Shah, Supriya A; Buncher, C Ralph; Sallans, Larry; Limbach, Patrick A; Schwemberger, Sandy; Babcock, George F; Knudsen, Karen E (2006. ) Bisphenol A facilitates bypass of androgen ablation therapy in prostate cancer.Molecular cancer therapeutics, , 5 (12 ) ,3181-90 More Information

Clark, Heather M; Gamm, Jennifer; Huether, Carl A; Buncher, C Ralph; Pfau, Ruthann I Blough; Warren, Nancy Steinberg (2006. ) Genetic counselors and research: current practices and future directions.American journal of medical genetics. Part C, Seminars in medical genetics, , 142C (4 ) ,276-83 More Information

Gilbert, Donald L; Buncher, C Ralph (2006. ) Epileptiform discharges and the behavior of children with epilepsy.The Journal of pediatrics, , 149 (2 ) ,283; author reply 28 More Information

Gilbert, Donald L; Buncher, C Ralph (2005. ) Assessment of scientific and ethical issues in two randomized clinical trial designs for patients with Tourette's syndrome: a model for studies of multiple neuropsychiatric diagnoses.The Journal of neuropsychiatry and clinical neurosciences, , 17 (3 ) ,324-32 More Information

Khoury, J C; Miodovnik, M; Buncher, C R; Kalkwarf, H; McElvy, S; Khoury, P R; Sibai, B (2004. ) Consequences of smoking and caffeine consumption during pregnancy in women with type 1 diabetes.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, , 15 (1 ) ,44-50 More Information

Gilbert, Donald L; Sethuraman, Gopalan; Kotagal, Uma; Buncher, C Ralph (2003. ) Meta-analysis of EEG test performance shows wide variation among studies. Neurology, , 60 (4 ) ,564-70

Jazieh, Abdul R; Buncher, Charles R (2002. ) Racial and age-related disparities in obtaining screening mammography: results of a statewide database. Southern medical journal, , 95 (10 ) ,1145-8

Pomerantz, W J; Dowd, M D; Buncher, C R (2001. ) Relationship between socioeconomic factors and severe childhood injuries.Journal of urban health : bulletin of the New York Academy of Medicine, , 78 (1 ) ,141-51 More Information

Gilbert, D L; Buncher, C R (2000. ) An EEG should not be obtained routinely after first unprovoked seizure in childhood. Neurology, , 54 (3 ) ,635-41

Iannaccone, S T; Russman, B S; Browne, R H; Buncher, C R; White, M; Samaha, F J (2000. ) Prospective analysis of strength in spinal muscular atrophy. DCN/Spinal Muscular Atrophy Group. Journal of child neurology, , 15 (2 ) ,97-101

Buncher, C R; Morrison, J A (1998. ) Those confounding variables! .The Journal of pediatrics, , 133 (2 ) ,174-5

Linz, D H; Pinney, S M; Keller, J D; White, M; Buncher, C R (1998. ) Cluster analysis applied to building-related illness. Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine, , 40 (2 ) ,165-71

Kuempel, E D; Stayner, L T; Attfield, M D; Buncher, C R (1996. ) Possible misclassification did not obscure detection of exposure-response.American journal of industrial medicine, , 30 (5 ) ,643-4 More Information

Russman, B S; Buncher, C R; White, M; Samaha, F J; Iannaccone, S T (1996. ) Function changes in spinal muscular atrophy II and III. The DCN/SMA Group. Neurology, , 47 (4 ) ,973-6

Creticos, P S; Reed, C E; Norman, P S; Khoury, J; Adkinson, N F; Buncher, C R; Busse, W W; Bush, R K; Gadde, J; Li, J T (1996. ) Ragweed immunotherapy in adult asthma.The New England journal of medicine, , 334 (8 ) ,501-6 More Information

Taha, J M; Tew, J M; Buncher, C R (1995. ) A prospective 15-year follow up of 154 consecutive patients with trigeminal neuralgia treated by percutaneous stereotactic radiofrequency thermal rhizotomy.Journal of neurosurgery, , 83 (6 ) ,989-93 More Information

Leikauf, G D; Kline, S; Albert, R E; Baxter, C S; Bernstein, D I; Bernstein, J; Buncher, C R (1995. ) Evaluation of a possible association of urban air toxics and asthma. Environmental health perspectives, , 103 Suppl 6 ,253-71

Kuempel, E D; Stayner, L T; Attfield, M D; Buncher, C R (1995. ) Exposure-response analysis of mortality among coal miners in the United States. American journal of industrial medicine, , 28 (2 ) ,167-84

Tian, J J; Shukla, R; Buncher, C R (1994. ) On prediction of future observation in growth curve model. Statistics in medicine, , 13 (21 ) ,2205-17

Samaha, F J; Buncher, C R; Russman, B S; White, M L; Iannaccone, S T; Barker, L; Burhans, K; Smith, C; Perkins, B; Zimmerman, L (1994. ) Pulmonary function in spinal muscular atrophy. Journal of child neurology, , 9 (3 ) ,326-9

Betemps, E J; Buncher, C R; Clark, C S (1994. ) Proportional mortality analysis of wastewater treatment system workers by birthplace with comments on amyotrophic lateral sclerosis. Journal of occupational medicine. : official publication of the Industrial Medical Association, , 36 (1 ) ,31-5

Pavelic, Z P; Portugal, L G; Gootee, M J; Stambrook, P J; Smith, C; Mugge, R E; Pavelic, L; Wilson, K; Buncher, C R; Li, Y Q (1993. ) Retrieval of p53 protein in paraffin-embedded head and neck tumor tissues. Archives of otolaryngology--head & neck surgery, , 119 (11 ) ,1206-9

Betemps, E J; Buncher, C R (1993. ) Birthplace as a risk factor in motor neurone disease and Parkinson's disease. International journal of epidemiology, , 22 (5 ) ,898-904

Iannaccone, S T; Browne, R H; Samaha, F J; Buncher, C R Prospective study of spinal muscular atrophy before age 6 years. DCN/SMA Group. Pediatric neurology, , 9 (3 ) ,187-93

Betemps, E J; Somoza, E; Buncher, C R (1993. ) Hospital characteristics, diagnoses, and staff reasons associated with use of seclusion and restraint. Hospital & community psychiatry, , 44 (4 ) ,367-71

Russman, B S; Iannacone, S T; Buncher, C R; Samaha, F J; White, M; Perkins, B; Zimmerman, L; Smith, C; Burhans, K; Barker, L (1992. ) Spinal muscular atrophy: new thoughts on the pathogenesis and classification schema. Journal of child neurology, , 7 (4 ) ,347-53

Betemps, E J; Buncher, C R; Oden, M (1992. ) Length of time spent in seclusion and restraint by patients at 82 VA medical centers. Hospital & community psychiatry, , 43 (9 ) ,912-4

Lanphear, B P; Buncher, C R (1992. ) Latent period for malignant mesothelioma of occupational origin. Journal of occupational medicine. : official publication of the Industrial Medical Association, , 34 (7 ) ,718-21

Buncher, C R; Collins, J J; Halperin, W (1991. ) Possible progress and unresolved conflicts resulting from guidelines on good epidemiologic practices. Journal of occupational medicine. : official publication of the Industrial Medical Association, , 33 (12 ) ,1261-4

Collins, J J; Buncher, C R; Halperin, W (1991. ) Managing the quality and conduct of epidemiologic studies. Journal of occupational medicine. : official publication of the Industrial Medical Association, , 33 (12 ) ,1213-5

Foulkes, E C; Mort, T L; Buncher, C R (1991. ) Intestinal cadmium permeability in mature and immature rats. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , 197 (4 ) ,477-81

Denman, D L; Legorreta, R A; Kier, A B; Elson, H R; White, M L; Buncher, C R; Lewis, G C; Born, A M; Sundararaman, S; Aron, B S (1991. ) Therapeutic responses of spontaneous canine malignancies to combinations of radiotherapy and hyperthermia. International journal of radiation oncology, biology, physics, , 21 (2 ) ,415-22

Buncher, C R; Succop, P A; Dietrich, K N (1991. ) Structural equation modeling in environmental risk assessment. Environmental health perspectives, , 90 ,209-13

Dietrich, K N; Succop, P A; Bornschein, R L; Krafft, K M; Berger, O; Hammond, P B; Buncher, C R (1990. ) Lead exposure and neurobehavioral development in later infancy. Environmental health perspectives, , 89 ,13-9

Buncher, C R; Samaha, F; Iannaccone, S T; Russman, B S; Cook, J D; White, M; McLaughlin, C (1990. ) Statistical considerations in the study of spinal muscular atrophy. Dallas-Cincinnati-Newington Spinal Muscular Atrophy (DCN-SMA) Study Group. Muscle & nerve, , 13 Suppl ,S45-8

Buncher, C R (1989. ) Did formaldehyde cause lung cancer? .Journal of occupational medicine. : official publication of the Industrial Medical Association, , 31 (11 ) ,885

Shukla, R; Bornschein, R L; Dietrich, K N; Buncher, C R; Berger, O G; Hammond, P B; Succop, P A (1989. ) Fetal and infant lead exposure: effects on growth in stature. Pediatrics, , 84 (4 ) ,604-12

Fowler, N O; Gabel, M; Buncher, C R (1988. ) Cardiac tamponade: a comparison of right versus left heart compression. Journal of the American College of Cardiology, , 12 (1 ) ,187-93

Buncher, C R (1988. ) Statistics in sports injury research. The American journal of sports medicine, , 16 Suppl 1 ,S57-62

Keller, C S; Noyes, F R; Buncher, C R (1988. ) The medical aspects of soccer injury epidemiology. The American journal of sports medicine, , 16 Suppl 1 ,S105-12

Kaufman, R A; Carroll, C D; Buncher, C R Atlantooccipital junction: standards for measurement in normal children. AJNR. American journal of neuroradiology, , 8 (6 ) ,995-9

Specker, B L; Saenger, E L; Buncher, C R; McDevitt, R A (1987. ) Pulmonary embolism and lung scanning: cost-effectiveness and benefit:risk. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, , 28 (10 ) ,1521-30

Keller, C S; Noyes, F R; Buncher, C R The medical aspects of soccer injury epidemiology. The American journal of sports medicine, , 15 (3 ) ,230-7

Saenger, E L; Buncher, C R; Specker, B L; McDevitt, R A (1985. ) Determination of clinical efficacy: nuclear medicine as applied to lung scanning. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, , 26 (7 ) ,793-806

Bonventre, P F; Linnemann, C; Weckbach, L S; Staneck, J L; Buncher, C R; Vigdorth, E; Ritz, H; Archer, D; Smith, B (1984. ) Antibody responses to toxic-shock-syndrome (TSS) toxin by patients with TSS and by healthy staphylococcal carriers. The Journal of infectious diseases, , 150 (5 ) ,662-6

Berlin, N I; Buncher, C R; Fontana, R S; Frost, J K; Melamed, M R (1984. ) The National Cancer Institute Cooperative Early Lung Cancer Detection Program. Results of the initial screen (prevalence). Early lung cancer detection: Introduction.The American review of respiratory disease, , 130 (4 ) ,545-9 More Information

Linnemann, C C; Staneck, J L; Hornstein, S; Barden, T P; Rauh, J L; Bonventre, P F; Buncher, C R; Beiting, A (1982. ) The epidemiology of genital colonization with Staphylococcus aureus. Annals of internal medicine, , 96 (6 Pt 2 ) ,940-4

Gartside, P S; Buncher, C R; Lerner, S (1982. ) Relationship of air lead and blood lead for workers at an automobile battery factory. International archives of occupational and environmental health, , 50 (1 ) ,1-10

Maxon, H R; Saenger, E L; Buncher, C R; Thomas, S R; Kereiakes, J G; Shafer, M L; McLaughlin, C A Radiation-associated carcinoma of the salivary glands. A controlled study. The Annals of otology, rhinology, and laryngology, , 90 (2 Pt 1 ) ,107-8

Emmett, E A; Buncher, C R; Suskind, R B; Rowe, K W (1981. ) Skin and eye diseases among arc welders those exposed to welding operations. Journal of occupational medicine. : official publication of the Industrial Medical Association, , 23 (2 ) ,85-90

Elia, V J; Anderson, L A; Macdonald, T J; Carson, A; Buncher, C R; Brooks, S M (1980. ) Determination of urinary mandelic and phenylglyoxylic acids in styrene exposed workers and a control population.American Industrial Hygiene Association journal, , 41 (12 ) ,922-6 More Information

Maxon, H R; Saenger, E L; Thomas, S R; Buncher, C R; Kereiakes, J G; Shafer, M L; McLaughlin, C A (1980. ) Clinically important radiation-associated thyroid disease. A controlled study. JAMA, , 244 (16 ) ,1802-5

Buncher, C R (1980. ) National Cancer Institute study: evaluation of computed tomography in the diagnosis of intracranial neoplasms. II. Was randomization necessary?.Radiology, , 136 (3 ) ,651-5 More Information

Tsang, R; Abrams, L; Joyce, T H; Buncher, C R; Steichen, J J (1979. ) Ionized Ca in neonates in relation to gestational age. The Journal of pediatrics, , 94 (1 ) ,126-9

Mandybur, T I; Ormsby, I; Buncher, C R (1978. ) Enhanced development of mammary tumors in rats following transplacental and neonatal exposure to ethylnitrosourea. Cancer research, , 38 (10 ) ,3182-5

Maxon, H R; Thomas, S R; Saenger, E L; Buncher, C R; Kereiakes, J G (1977. ) Ionizing irradiation and the induction of clinically significant disease in the human thyroid gland. The American journal of medicine, , 63 (6 ) ,967-78

Buncher, C R (1977. ) The golden fleece award: a control?.Science (New York, N.Y.), , 197 (4308 ) ,1036 More Information

Kuzma, R J; Kuzma, C M; Buncher, C R (1977. ) Ohio drinking water source and cancer rates. American journal of public health, , 67 (8 ) ,725-9

Buncher, C R (1977. ) Health records.Science (New York, N.Y.), , 195 (4277 ) ,440 More Information

Glueck, C J; Mellies, M J; Srivastava, L; Knowles, H C; Fallat, R W; Tsang, R C; Wacholder, S; Buncher, C R (1977. ) Insulin, obesity, and triglyceride interrelationships in sixteen children with familial hypertriglyceridemia. Pediatric research, , 11 (1 Pt 1 ) ,13-9

Buncher, C R (1976. ) On professor Okun's paper. American journal of public health, , 66 (11 ) ,1108

Linnemann, C C; Levinson, J E; Buncher, C R; Schiff, G M (1975. ) Rubella antibody levels in juvenile rheumatoid arthritis. Annals of the rheumatic diseases, , 34 (4 ) ,354-8

Namboodiri, K K; Elston, R C; Glueck, C J; Fallat, R; Buncher, C R; Tsang, R (1975. ) Bivariate analyses of cholesterol and triglyceride levels in families in which probands have type IIb lipoprotein phenotype. American journal of human genetics, , 27 (4 ) ,454-71

Plank, S J; Buncher, C R (1975. ) Maternal ABO groups and the sex ratio of live births. Human heredity, , 25 (3 ) ,226-33

Lutmer, R F; Parsons, D; Glueck, C J; Morrison, J A; Stewart, L; Brazier, J B; Buncher, C R; Ishikawa, T T (1974. ) Analysis of alpha-lipoprotein cholesterol in 50 microl of plasma. Journal of lipid research, , 15 (6 ) ,611-4

Glueck, C J; Fallat, R W; Tsang, R; Buncher, C R (1974. ) Hyperlipemia in progeny of parents with myocardial infarction before age 50. American journal of diseases of children (1960), , 127 (1 ) ,70-5

Glueck, C J; Fallat, R; Buncher, C R; Tsang, R; Steiner, P (1973. ) Familial combined hyperlipoproteinemia: studies in 91 adults and 95 children from 33 kindreds. Metabolism: clinical and experimental, , 23 (2 ) ,1403-28

Glueck, C J; Tsang, R; Fallat, R; Buncher, C R; Evans, G; Steiner, P (1973. ) Familial hypertriglyceridemia: studies in 130 children and 45 siblings of 36 index cases. Metabolism: clinical and experimental, , 22 (10 ) ,1287-309

Buncher, C R (1973. ) Sounding board "administratively significant".The New England journal of medicine, , 289 (3 ) ,155-6 More Information

Tal, C; Raychaudhuri, A; Megel, H; Herberman, R B; Buncher, C R (1973. ) Simplified technique for the T-globulin cancer test. Journal of the National Cancer Institute, , 51 (1 ) ,33-43

Blackwell, B; Bloomfield, S S; Buncher, C R (1972. ) Demonstration to medical students of placebo responses and non-drug factors. Lancet (London, England), , 1 (7763 ) ,1279-82

Sampson, R J; Key, C R; Buncher, C R; Iijima, S (1971. ) Smallest forms of papillary carcinoma of the thyroid. A study of 141 microcarcinomas less than 0.1 cm in greatest dimension. Archives of pathology, , 91 (4 ) ,334-9

Sampson, R J; Key, C R; Buncher, C R; Oka, H; Iijima, S (1970. ) Papillary carcinoma of the thyroid gland. Sizes of 525 tumors found at autopsy in Hiroshima and Nagasaki. Cancer, , 25 (6 ) ,1391-3

Sampson, R J; Oka, H; Key, C R; Buncher, C R; Iijima, S (1970. ) Metastases from occult thyroid carcinoma. An autopsy study from Hiroshima and Nagasaki, Japan. Cancer, , 25 (4 ) ,803-11

Sampson, R J; Key, C R; Buncher, C R; Iijima, S (1969. ) Thyroid carcinoma in Hiroshima and Nagasaki. I. Prevalence of thyroid carcinoma at autopsy. JAMA, , 209 (1 ) ,65-70

Dear, H D; Buncher, C R; Sawayama, T (1969. ) Changes in electrocardiogram and serum potassium values following glucose ingestion. Archives of internal medicine, , 124 (1 ) ,25-8

Buncher, C R (1969. ) Cigarette smoking and duration of pregnancy. American journal of obstetrics and gynecology, , 103 (7 ) ,942-6

Kimura, K; Hiramoto, T; Buncher, C R (1969. ) Gastric xanthelasma. Archives of pathology, , 87 (1 ) ,110-7

Published Books

Buncher et al. (2006. ) Statistics in the Pharmaceutical Industry .Boca Raton, FL , Chapman &Hall/CRC (Co-Editor)


Pharmacoeconomics(MeSH PhrmEco),Pharmacoepidemiology(MeSH PhrmEpi),Diseases(MeSH C),Health Care(MeSH N),Health Care Quality, Access, and Evaluation(MeSH N05),Population Characteristics(MeSH N01),Health Care Economics and Organizations(MeSH N03),Neoplasms(MeSH C04),Environmental Pollutants, Noxae, and Pesticides(MeSH D05),Investigative Techniques(MeSH E05),Education(MeSH I02)