Long (Jason) Lu , PhD

Bachelor's Degree: Peking University 1998 (Biotechnology/Bioengineering)

Doctoral Degree: Washington University School of Medicine 2003 (Biochemistry, specialized in Computational Molecular Biology)

Postdoctorate: Yale University 2006 (Bioinformatics)

Peer Reviewed Publications

Gordon SM, Li H, Zhu X, Tso P, Reardon CA, Shah AS, Lu LJ, Davidson WS. (09-2012. ) Impact of genetic deletion of platform apolipoproteins on the size distribution of the murine lipoproteome.J Proteomics., , 146 ,184 More Information

Tan L, Holland SK, Deshpande AK, Chen Y, Choo DI, Lu LJ. (10-2015. ) A semi-supervised Support Vector Machine model for predicting the language outcomes following cochlear implantation based on pre-implant brain fMRI imaging.Brain Behav., , 5 (12 ) ,e00391 More Information

Deshpande AK, Tan L, Lu LJ, Altaye M, Holland SK. (07-2016. ) fMRI as a Preimplant Objective Tool to Predict Postimplant Oral Language Outcomes in Children with Cochlear Implants.Ear Hear., , 37 (4 ) ,e263 More Information

Cai WF, Liu GS, Lam CK, Florea S, Qian J, Zhao W, Pritchard T, Haghighi K, Lebeche D, Lu LJ, Deng J, Fan GC, Hajjar RJ, Kranias EG. (08-2015. ) Up-regulation of micro-RNA765 in human failing hearts is associated with post-transcriptional regulation of protein phosphatase inhibitor-1 and depressed contractility.Eur J Heart Fail., , 17 (8 ) ,782 More Information

Li H, Gordon SM, Zhu X, Deng J, Swertfeger DK, Davidson WS, Lu LJ. (08-2015. ) Network-Based Analysis on Orthogonal Separation of Human Plasma Uncovers Distinct High Density Lipoprotein Complexes.J Proteome Res., , 14 (8 ) ,3082 More Information

Panmanee W.;Su S.;Schurr M.;Lau G.;Zhu X.;Ren Z.;McDaniel C.;Lu L.;Ohman D.;Muruve D.;Panos R.;Yu H.;Thompson T.;Tseng B.;Hassett D. (06-01-2019. ) The anti-sigma factor MucA of Pseudomonas aeruginosa: Dramatic differences of a mucA22 vs. A ?mucA m.PLoS ONE, , 14 (6 ) , More Information

Swertfeger D.;Rebholz S.;Li H.;Shah A.;Davidson W.;Lu L. (11-01-2018. ) Feasibility of a plasma bioassay to assess oxidative protection of low-density lipoproteins by high-.Journal of Clinical Lipidology, , 12 (6 ) ,1539-1548 More Information

Deshpande A.;Tan L.;Lu L.;Altaye M.;Holland S. (05-01-2018. ) fMRI as a preimplant objective tool to predict children's postimplant auditory and language outcomes.Journal of the American Academy of Audiology, , 29 (5 ) ,389-404 More Information

Brewington J.J.;Backstrom J.;Feldman A.;Kramer E.L.;Moncivaiz J.D.;Ostmann A.J.;Zhu X.;Lu L.J.;Clancy J.P. (02-22-2018. ) Chronic ?2AR stimulation limits CFTR activation in human airway epithelia.JCI insight, , 3 (4 ) , More Information

Zhu X.;Shah A.S.;Swertfeger D.K.;Li H.;Ren S.;Melchior J.T.;Gordon S.M.;Davidson W.S.;Lu L.J. (01-01-2018. ) High-density lipoproteins-associated proteins and subspecies related to arterial stiffness in young .Complexity, , 2018 , More Information

Tan L.;Guo X.;Ren S.;Epstein J.N.;Lu L.J. (09-08-2017. ) A computational model for the automatic diagnosis of attention deficit hyperactivity disorder based .Frontiers in Computational Neuroscience, , 11 , More Information

Guo X.;Dominick K.C.;Minai A.A.;Li H.;Erickson C.A.;Lu L.J. (08-21-2017. ) Diagnosing autism spectrum disorder from brain resting-state functional connectivity patterns using .Frontiers in Neuroscience, , 11 (AUG ) , More Information

Guo X.;Minai A.;Lu L. (06-30-2017. ) Feature selection using multiple auto-encoders.Proceedings of the International Joint Conference on Neural Networks, , 2017-May ,4602-4609 More Information

Swertfeger D.;Li H.;Rebholz S.;Zhu X.;Shah A.;Davidson W.;Lu L. (04-01-2017. ) Mapping atheroprotective functions and related proteins/lipoproteins in size fractionated human plas.Molecular and Cellular Proteomics, , 16 (4 ) ,680-693 More Information

Melchior J.;Street S.;Andraski A.;Furtado J.;Sacks F.;Shute R.;Greve E.;Swertfeger D.;Li H.;Shah A.;Lu L.;Davidson W. (01-01-2017. ) Apolipoprotein A-II alters the proteome of human lipoproteins and enhances cholesterol efflux from A.Journal of Lipid Research, , 58 (7 ) ,1374-1385 More Information

Gordon S.;Li H.;Zhu X.;Tso P.;Reardon C.;Shah A.;Lu L.;Davidson W. (09-02-2016. ) Impact of genetic deletion of platform apolipoproteins on the size distribution of the murine lipopr.Journal of Proteomics, , 146 ,184-194 More Information

Deshpande A.;Tan L.;Lu L.;Altaye M.;Holland S. (07-01-2016. ) FMRI as a Preimplant Objective Tool to Predict Postimplant Oral Language Outcomes in Children with C.Ear and Hearing, , 37 (4 ) ,e263-e272 More Information

Gordon S.;Davidson W.;Urbina E.;Dolan L.;Heink A.;Zang H.;Lu L.;Shah A. (07-01-2016. ) Erratum: The effects of type 2 diabetes on lipoprotein composition and arterial stiffness in male yo.Diabetes, , 65 (7 ) ,2100 More Information

Chen Y.;Mazlack L.;Minai A.;Lu L. (12-01-2015. ) Inferring causal networks using fuzzy cognitive maps and evolutionary algorithms with application to.Applied Soft Computing Journal, , 37 ,667-679 More Information

Ren S.;Hinzman A.A.;Kang E.L.;Szczesniak R.D.;Lu L.J. (12-01-2015. ) Computational and statistical analysis of metabolomics data.Metabolomics, , 11 (6 ) ,1492-1513 More Information

Tan L.;Holland S.;Deshpande A.;Chen Y.;Choo D.;Lu L. (12-01-2015. ) A semi-supervised Support Vector Machine model for predicting the language outcomes following cochle.Brain and Behavior, , 5 (12 ) ,1-25 More Information

Li H.;Gordon S.;Zhu X.;Deng J.;Swertfeger D.;Davidson W.;Lu L. (08-07-2015. ) Network-Based Analysis on Orthogonal Separation of Human Plasma Uncovers Distinct High Density Lipop.Journal of Proteome Research, , 14 (8 ) ,3082-3094 More Information

Cai W.;Liu G.;Lam C.;Florea S.;Qian J.;Zhao W.;Pritchard T.;Haghighi K.;Lebeche D.;Lu L.;Deng J.;Fan G.;Hajjar R.;Kranias E. (08-01-2015. ) Up-regulation of micro-RNA765 in human failing hearts is associated with post-transcriptional regula.European Journal of Heart Failure, , 17 (8 ) ,782-793 More Information

Lu Y.;Lu Y.;Deng J.;Peng H.;Lu H.;Lu L.J. (07-31-2015. ) A novel essential domain perspective for exploring gene essentiality.Bioinformatics, , 31 (18 ) ,2921-2929 More Information

Heink A.;Davidson W.;Swertfeger D.;Lu L.;Shah A. (07-02-2015. ) A Comparison of Methods to Enhance Protein Detection of Lipoproteins by Mass Spectrometry.Journal of Proteome Research, , 14 (7 ) ,2943-2950 More Information

Gordon S.;Li H.;Zhu X.;Shah A.;Lu L.;Davidson W. (06-05-2015. ) A comparison of the mouse and human lipoproteome: Suitability of the mouse model for studies of huma.Journal of Proteome Research, , 14 (6 ) ,2686-2695 More Information

Lu L. (01-01-2015. ) Preface. Gene essentiality .Methods in molecular biology (Clifton, N.J.), , 1279 ,v

Lu Y.;Lu Y.;Deng J.;Lu H.;Lu L.J. (01-01-2015. ) Discovering essential domains in essential genes.Methods in Molecular Biology, , 1279 ,235-245 More Information

Krishnan K.;Ren Z.;Losada L.;Nierman W.;Lu L.;Askew D. (02-25-2014. ) Polysome profiling reveals broad translatome remodeling during endoplasmic reticulum (ER) stress in .BMC Genomics, , 15 (1 ) , More Information

Chen Y.;Storrs J.;Tan L.;Mazlack L.;Lee J.;Lu L. (01-15-2014. ) Detecting brain structural changes as biomarker from magnetic resonance images using a local feature.Journal of Neuroscience Methods, , 221 ,22-31 More Information

Lu Y.;Deng J.;Rhodes J.;Lu H.;Lu L. (01-01-2014. ) Predicting essential genes for identifying potential drug targets in Aspergillus fumigatus.Computational Biology and Chemistry, , 50 ,29-40 More Information

Lu Y.;Deng J.;Carson M.;Lu H.;Lu L. (01-01-2014. ) Computational methods for the prediction of microbial essential genes.Current Bioinformatics, , 9 (2 ) ,89-101 More Information

Tan L.;Chen Y.;Maloney T.;Caré M.;Holland S.;Lu L. (11-11-2013. ) Combined analysis of sMRI and fMRI imaging data provides accurate disease markers for hearing impair.NeuroImage: Clinical, , 3 ,416-428 More Information

Gordon S.;Deng J.;Tomann A.;Shah A.;Lu L.;Davidson W. (11-01-2013. ) Multi-dimensional co-separation analysis reveals protein-protein interactions defining plasma lipopr.Molecular and Cellular Proteomics, , 12 (11 ) ,3123-3134 More Information

Gordon S.;Davidson W.;Urbina E.;Dolan L.;Heink A.;Zang H.;Lu L.;Shah A. (08-01-2013. ) The effects of type 2 diabetes on lipoprotein composition and arterial stiffness in male youth.Diabetes, , 62 (8 ) ,2958-2967 More Information

Deng J.;Su S.;Lin X.;Hassett D.;Lu L. (03-08-2013. ) A Statistical Framework for Improving Genomic Annotations of Prokaryotic Essential Genes.PLoS ONE, , 8 (3 ) , More Information

Chen Y.;Mazlack L.;Lu L. (12-01-2012. ) Inferring fuzzy cognitive map models for gene regulatory networks from gene expression data.Proceedings - 2012 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2012, , 598-601 More Information

Chen Y.;Mazlack L.;Lu L. (10-26-2012. ) Fuzzy cognitive maps development using ant colony optimization with local search procedure.2012 Annual Meeting of the North American Fuzzy Information Processing Society, NAFIPS 2012, , More Information

Zhang M.;Su S.;Bhatnagar R.;Hassett D.;Lu L. (07-24-2012. ) Prediction and analysis of the protein interactome in Pseudomonas aeruginosa to enable network-based.PLoS ONE, , 7 (7 ) , More Information

Deng J.;Tan L.;Lin X.;Lu Y.;Lu L. (01-01-2012. ) Exploring the optimal strategy to predict essential genes in microbes.Biomolecules, , 2 (1 ) ,1-22 More Information

Feng X.;Krishnan K.;Richie D.;Aimanianda V.;Hartl L.;Grahl N.;Powers-Fletcher M.;Zhang M.;Fuller K.;Nierman W.;Lu L.;Latgé J.;Woollett L.;Newman S.;Cramer R.;Rhodes J.;Askew D. (10-01-2011. ) Haca-independent functions of the ER stress sensor irea synergize with the canonical UPR to influenc.PLoS Pathogens, , 7 (10 ) , More Information

Ren J.;Jegga A.;Zhang M.;Deng J.;Liu J.;Gordon C.;Aronow B.;Lu L.;Zhang B.;Ma J. (09-01-2011. ) A Drosophila model of the neurodegenerative disease SCA17 reveals a role of RBJ-J/Su(H) in modulatin.Human Molecular Genetics, , 20 (17 ) ,3424-3436 More Information

Zhang M.;Zhu C.;Jacomy A.;Lu L.;Jegga A. (06-10-2011. ) The orphan disease networks.American Journal of Human Genetics, , 88 (6 ) ,755-766 More Information

Deng J.;Deng L.;Su S.;Zhang M.;Lin X.;Wei L.;Minai A.;Hassett D.;Lu L. (01-01-2011. ) Investigating the predictability of essential genes across distantly related organisms using an inte.Nucleic Acids Research, , 39 (3 ) ,795-807 More Information

Zhang M.;Fang C.;Xu Y.;Bhatnagar R.;Lu L. (12-01-2010. ) An Integrative scoring approach to identify transcriptional regulations controlling lung surfactant .Proceedings - IEEE International Conference on Data Mining, ICDM, , 787-792 More Information

Gordon S.;Deng J.;Lu L.;Davidson W. (10-01-2010. ) Proteomic characterization of human plasma high density lipoprotein fractionated by gel filtration c.Journal of Proteome Research, , 9 (10 ) ,5239-5249 More Information

Zhang M.;Lu L. (09-16-2010. ) Investigating the validity of current network analysis on static conglomerate networks by protein ne.BMC Bioinformatics, , 11 , More Information

Deng J.;Wang W.;Lu L.;Ma J. (09-10-2010. ) A two-dimensional simulation model of the bicoid gradient in Drosophila.PLoS ONE, , 5 (4 ) , More Information

He F.;Wen Y.;Cheung D.;Deng J.;Lu L.;Jiao R.;Ma J. (08-05-2010. ) Distance measurements via the morphogen gradient of Bicoid in Drosophila embryos.BMC Developmental Biology, , 10 , More Information

Xu Y.;Zhang M.;Wang Y.;Kadambi P.;Dave V.;Lu L.;Whitsett J. (07-26-2010. ) A systems approach to mapping transcriptional networks controlling surfactant homeostasis.BMC Genomics, , 11 (1 ) , More Information

Zhang M.;Deng J.;Fang C.;Zhang X.;Lu L. (07-07-2010. ) Molecular Network Analysis and Applications.Knowledge-Based Bioinformatics: From Analysis to Interpretation, , 251-287 More Information

He F.;Wen Y.;Deng J.;Lin X.;Lu L.;Jiao R.;Ma J. (10-14-2008. ) Probing Intrinsic Properties of a Robust Morphogen Gradient in Drosophila.Developmental Cell, , 15 (4 ) ,558-567 More Information

Huang Y.J.;Hang D.;Lu L.J.;Tong L.;Gerstein M.B.;Montelione G.T. (10-01-2008. ) Targeting the human cancer pathway protein interaction network by structural genomics.Molecular and Cellular Proteomics, , 7 (10 ) ,2048-2060 More Information

Wu L.;Hwang S.I.;Rezaul K.;Lu L.J.;Mayya V.;Gerstein M.;Eng J.K.;Lundgren D.H.;Han D.K. (08-01-2007. ) Global survey of human T leukemic cells by integrating proteomics and transcriptomics profiling.Molecular and Cellular Proteomics, , 6 (8 ) ,1343-1353 More Information

Lu L.J.;Sboner A.;Huang Y.J.;Lu H.X.;Gianoulis T.A.;Yip K.Y.;Kim P.M.;Montelione G.T.;Gerstein M.B. (07-01-2007. ) Comparing classical pathways and modern networks: towards the development of an edge ontology.Trends in Biochemical Sciences, , 32 (7 ) ,320-331 More Information

Flores S.;Lu L.;Yang J.;Carriero N.;Gerstein M. (05-22-2007. ) Hinge Atlas: Relating protein sequence to sites of structural flexibility.BMC Bioinformatics, , 8 , More Information

Kim P.;Lu L.;Xia Y.;Gerstein M. (12-01-2006. ) Relating three-dimensional structures to protein networks provides evolutionary insights.Science, , 314 (5807 ) ,1938-1941 More Information

Xia Y.;Lu L.J.;Gerstein M. (03-17-2006. ) Integrated prediction of the helical membrane protein interactome in yeast.Journal of Molecular Biology, , 357 (1 ) ,339-349 More Information

Lu L.;Xia Y.;Paccanaro A.;Yu H.;Gerstein M. (07-01-2005. ) Assessing the limits of genomic data integration for predicting protein networks.Genome Research, , 15 (7 ) ,945-953 More Information

Lu L.;Xia Y.;Yu H.;Rives A.;Lu H.;Schubert F.;Gerstein M. (06-15-2005. ) Protein Interaction Prediction by Integrating Genomic Features and Protein Interaction Network Analy.Data Analysis and Visualization in Genomics and Proteomics, , 61-81 More Information

Academic - Cincinnati Children's Hospital Medical Center
Cincinnati  Ohio, 45229
Phone: 513-636-8720
long.lu@cchmc.org