Li Zhang

Li Zhang

Assoc Professor

Kettering Lab Complex

106

COM EH Biostat and Bioinfo Division - 0056

Professional Summary

Bioinformatics, particularly in the field of cancer genomics using deep learning and systems biology.

Education

PHD, University of North Carolina at Chapel Hill Chapel Hill, North carolina, USA, 1995 (Computational Structural Biology; Bioinformatics.)

Master of Science, Tsinghua University Beijing, China, 1988 (Biophysics)

BA, Wuhan University Wuhan, China, 1985 (Physics)

Publications

Peer Reviewed Publications

Fox, Melanie D; Xiao, Li; Zhang, Miao; Kamat, Ashish M; Siefker-Radtke, Arlene; Zhang, Li; Dinney, Colin P; Czerniak, Bogdan; Guo, Charles C (2017. )Plasmacytoid Urothelial Carcinoma of the Urinary Bladder: A Clinicopathologic and Immunohistochemical Analysis of 49 Cases.American journal of clinical pathology, ,147 (5 ),500-506

Mobley, Aaron; Zhang, Shizhen; Bondaruk, Jolanta; Wang, Yan; Majewski, Tadeusz; Caraway, Nancy P; Huang, Li; Shoshan, Einav; Velazquez-Torres, Guermarie; Nitti, Giovanni; Lee, Sangkyou; Lee, June Goo; Fuentes-Mattei, Enrique; Willis, Daniel; Zhang, Li; Guo, Charles C; Yao, Hui; Baggerly, Keith; Lotan, Yair; Lerner, Seth P; Dinney, Colin; McConkey, David; Bar-Eli, Menashe; Czerniak, Bogdan (2017. )Aurora Kinase A is a Biomarker for Bladder Cancer Detection and Contributes to its Aggressive Behavior.Scientific reports, ,7 ,40714

Dadhania, Vipulkumar; Zhang, Miao; Zhang, Li; Bondaruk, Jolanta; Majewski, Tadeusz; Siefker-Radtke, Arlene; Guo, Charles C; Dinney, Colin; Cogdell, David E; Zhang, Shizhen; Lee, Sangkyou; Lee, June G; Weinstein, John N; Baggerly, Keith; McConkey, David; Czerniak, Bogdan (2016. )Meta-Analysis of the Luminal and Basal Subtypes of Bladder Cancer and the Identification of Signature Immunohistochemical Markers for Clinical Use.EBioMedicine, ,12 ,105-117

Guo, Charles Chuanhai; Dadhania, Vipulkumar; Zhang, Li; Majewski, Tadeusz; Bondaruk, Jolanta; Sykulski, Maciej; Wronowska, Weronika; Gambin, Anna; Wang, Yan; Zhang, Shizhen; Fuentes-Mattei, Enrique; Kamat, Ashish Madhav; Dinney, Colin; Siefker-Radtke, Arlene; Choi, Woonyoung; Baggerly, Keith A; McConkey, David; Weinstein, John N; Czerniak, Bogdan (2016. )Gene Expression Profile of the Clinically Aggressive Micropapillary Variant of Bladder Cancer.European urology, ,70 (4 ),611-620

Tetzlaff, Michael T; Singh, Rajesh R; Seviour, Elena G; Curry, Jonathan L; Hudgens, Courtney W; Bell, Diana; Wimmer, Daniel A; Ning, Jing; Czerniak, Bogdan A; Zhang, Li; Davies, Michael A; Prieto, Victor G; Broaddus, Russell R; Ram, Prahlad; Luthra, Rajyalakshmi; Esmaeli, Bita (2016. )Next-generation sequencing identifies high frequency of mutations in potentially clinically actionable genes in sebaceous carcinoma.The Journal of pathology, ,240 (1 ),84-95

Research and Practice Interests

Research interests: Bioinformatics, particularly in the field of cancer genomics using deep learning and systems biology. Development of analytical pipelines that process genomic sequencing data to extract genetic, epi-genetic and transcriptomic information for cancer research. Current projects include: (1) Pattern recognition in massive genomic data using deep learning; (2) Data analysis and visualization of single cell RNAseq data; (3) Integrative genomic analysis of bladder cancers; (4) Analysis of DNA methylation data in epigenetic studies.

Contact Information

zhang3l3@ucmail.uc.edu