Cal  Adler

Cal Adler

Professor of Psychiatry and Behavioral Neuroscience; Vice Chair of Research; Co-Director of the Division of Bipolar Disorders Research; and Director of the Center for Imaging Research

One Stetson Square

3272

COM Psychiatry Clinical Research - 0516

Stenson Building
Suite 3200
Cincinnati, Ohio 45219

Professional Summary

DR. CAL ADLER is a Professor of Psychiatry and Neuroscience. He is the Vice Chair of Clinical Research. He is co-director of the Division of Bipolar Disorders Research and Director of the Center for Imaging Research of the College of Medicine. Dr. Adler received a B.S. from the Pennsylvania State University and an M.D. from Jefferson Medical College of the Thomas Jefferson University. Dr. Adler completed residency in psychiatry at Georgetown University Medical Center, where he was a Chief Resident and a Senior Staff Fellowship in the Experimental Therapeutics Branch of the National Institute of Mental Health. Dr. Adler’s research interests include the use of neuroimaging techniques to study both healthy cognitive processes and the neuropathophysiology of bipolar and psychotic disorders, as well as the psychopharmacologic treatment of bipolar disorder.

Education

Bachelor's Degree, Pennsylvania State University

Medical Degree, Jefferson Medical College of the Thomas Jefferson University

Residency, Georgetown University Medical Center (Psychiatry)

Fellowship, National Institute of Mental Health (Experimental Therapeutics)

Research and Practice Interests

The use of neuroimaging techniques to study both healthy cognitive processes and the neuropathophysiology of bipolar and psychotic disorders, as well as the psychopharmacologic treatment of bipolar disorder.

UC Health Location

Clifton Stetson Physician Office

UCMC Outpatient Pavilion

UC Health Clinical Focus

Psychiatry

UC Health Specialities

Psychiatry

Certifications

American Board of Psychiatry and Neurology (Psychiatry)

03/31/1998

Research Support

Theodore & Vada Stanley Foundation The Neurophysiology of Attention in Euthymic Bipolar Disorder: a fMRI Study Role:Co-Principal Investigator

National Alliance for Research on Schizophrenia and Affective Disorders The Neuropathophysiology of Emotional Processing in Euthymic Bipolar Disorder Role:Principal Investigator

Bristol-Myers Squibb Company Nefazodone and Haloperidol Combination Therapy in the Treatment of Schizophrenia Role:Principal Investigator

Theodore & Vada Stanley Foundation D-cycloserine in the Treatment of Bipolar Depression Role:Principal Investigator

Grant: #1 K23 MH064086-01A2 National Institute of Mental Health Neurophysiology of Working Memory in Bipolar Disorder Role:Principal Investigator

National Alliance for Research on Schizophrenia and Affective Disorders Affective Episode-Related Changes in White Matter Integrity in Patients with Bipolar Disorder: A Diffusion Tensor Imaging Study Role:Principal Investigator

Grant: #5-K23-MH-64086-04-A0-S0-E0 Investigators:Adler, Caleb 01-01-2003 -12-31-2008 National Institute of Mental Health Neurophysiology of Working Memory in Bipolar Disorder: An fMRI Study Role:PI $903,906.00 Closed Level:Federal

Grant: #SRS 004960 Investigators:Adler, Caleb; Chu, Wen-Jang; Jarvis, Kelly; Strakowski, Stephen 07-01-2007 -06-30-2010 National Alliance for Research on Schizophrenia and Depression Clinical 1H MRS Studies of Glutamatergic Neurotransmission in Bipolar Disorder Role:Collaborator $60,000.00 Active Level:Private Non-Profit

Grant: #MH078043-1A1 Investigators:Adler, Caleb 08-14-2007 -05-31-2014 National Institute of Mental Health Neurofunctional and Neurochemical Markers of Treatment Response to Bipolar Mania Role:PI $1,761,394.00 Active Level:Federal

Grant: #F30 MH081461 Investigators:Adler, Caleb; Delbello, Melissa; Eliassen, James; Lamy, Martine; Lee, Jing-Huei; Shear, Paula; Strakowski, Stephen; Succop, Paul 12-01-2008 -06-30-2013 National Institute of Mental Health Neural Mechanisms of Impulsivity and Reward Processing in Bipolar Disorder Role:Collaborator $194,264.00 Active Level:Federal

Grant: #R21 MH083139 Investigators:Adler, Caleb; Komoroski, Richard; Strakowski, Stephen 02-01-2009 -11-30-2011 National Institute of Mental Health Magnetic Resonance Imaging of Lithium in Human Brain Role:Collaborator $431,125.00 Closed Level:Federal

Grant: #R01 MH080973 Investigators:Adler, Caleb; Chu, Wen-Jang; Delbello, Melissa; Komoroski, Richard; Lee, Jing-Huei; Shear, Paula; Strakowski, Stephen; Welge, Jeffrey 08-01-2009 -02-28-2014 National Institute of Mental Health Multimodal Neuroimaging of Treatment Effects in Adolescent Mania Role:Collaborator $3,520,432.00 Active Level:Federal

Grant: #3 R01 MH078043-03S1 Investigators:Adler, Caleb 09-30-2009 -05-31-2012 National Institute of Mental Health ARRA Admin Supplement: Neurofunctional and Neurochemical Markers of Treatment Response in Bipolar Mania Role:PI $730,065.00 Active Level:Federal

Grant: #K25 MH085103 Investigators:Adler, Caleb; Chu, Wen-Jang; Eliassen, James; Lee, Jing-Huei; Nasrallah, Henry; Nelson, Erik; Strakowski, Stephen 04-01-2010 -12-31-2013 National Institute of Mental Health Contrasting Glutamatergic Neurotransmission in Bipolar Disorder and Schizophrenia Role:Collaborator $495,850.00 Active Level:Federal

Grant: #S10OD011944 Investigators:Adler, Caleb; Clark, Joseph; Ho, Shuk Mei; Howarth, Jack; Komoroski, Richard; Lu, Aigang; Pyne-Geithman, Gail Jean; Rosevear, Paul; Strakowski, Stephen 04-02-2012 -03-31-2014 Office of the Director, National Institutes of Health Bruker Avance III Wide-Bore (89-mm, 9.4T), Vertical-Bore 400-Mhz NMR Spectrometer Role:Collaborator $595,000.00 Active Level:Federal

Grant: #Subgrqant Agreement Investigators:Adler, Caleb 11-01-2014 -12-31-2015 Administration for Children and Families Predictors of Outcome in Butler County Children's Services Role:PI $45,183.00 Active Level:Federal

Grant: #10367-002 Investigators:Adler, Caleb; Krikorian, Robert 07-01-2016 -06-30-2018 Department of Agriculture Blueberry Supplementation and Early Intervention in Cognitive Aging Role:Collaborator $175,902.00 Active Level:Federal

Publications

Peer Reviewed Publications

Strakowski, Stephen M; Fleck, David E; DelBello, Melissa P; Adler, Caleb M; Shear, Paula K; Kotwal, Renu; Arndt, Stephan (2010. )Impulsivity across the course of bipolar disorder.Bipolar disorders, ,12 (3 ),285-97

Strawn, Jeffrey R; Adler, Caleb M; Fleck, David E; Hanseman, Dennis; Maue, Danielle K; Bitter, Samantha; Kraft, Elizabeth M; Geracioti, Thomas D; Strakowski, Stephen M; DelBello, Melissa P (2010. )Post-traumatic stress symptoms and trauma exposure in youth with first episode bipolar disorder.Early intervention in psychiatry, ,4 (2 ),169-73

McNamara, Robert K; Able, Jessica; Jandacek, Ronald; Rider, Therese; Tso, Patrick; Eliassen, James C; Alfieri, David; Weber, Wade; Jarvis, Kelly; DelBello, Melissa P; Strakowski, Stephen M; Adler, Caleb M (2010. )Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging study.The American journal of clinical nutrition, ,91 (4 ),1060-7

DelBello, Melissa P; Chang, Kiki; Welge, Jeffrey A; Adler, Caleb M; Rana, Manasi; Howe, Meghan; Bryan, Holly; Vogel, Daniel; Sampang, Suzanne; Delgado, Sergio V; Sorter, Michael; Strakowski, Stephen M (2009. )A double-blind, placebo-controlled pilot study of quetiapine for depressed adolescents with bipolar disorder.Bipolar disorders, ,11 (5 ),483-93

Strakowski, Stephen M; Fleck, David E; DelBello, Melissa P; Adler, Caleb M; Shear, Paula K; McElroy, Susan L; Keck, Paul E; Moss, Quinton; Cerullo, Michael A; Kotwal, Renu; Arndt, Stephan (2009. )Characterizing impulsivity in mania.Bipolar disorders, ,11 (1 ),41-51

Epstein, J N; Delbello, M P; Adler, C M; Altaye, M; Kramer, M; Mills, N P; Strakowski, S M; Holland, S (2009. )Differential patterns of brain activation over time in adolescents with and without attention deficit hyperactivity disorder (ADHD) during performance of a sustained attention task.Neuropediatrics, ,40 (1 ),1-5

Cerullo, Michael A; Adler, Caleb M; Delbello, Melissa P; Strakowski, Stephen M (2009. )The functional neuroanatomy of bipolar disorder.International review of psychiatry (Abingdon, England), ,21 (4 ),314-22

Patel, Nick C; Cecil, Kim M; Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P (2008. )Neurochemical alterations in adolescent bipolar depression: a proton magnetic resonance spectroscopy pilot study of the prefrontal cortex.Journal of child and adolescent psychopharmacology, ,18 (6 ),623-7

Jarvis, Kelly; DelBello, Melissa P; Mills, Neil; Elman, Igor; Strakowski, Stephen M; Adler, Caleb M (2008. )Neuroanatomic comparison of bipolar adolescents with and without cannabis use disorders.Journal of child and adolescent psychopharmacology, ,18 (6 ),557-63

Strakowski, Stephen M; Adler, Caleb M; Cerullo, Michael A; Eliassen, James C; Lamy, Martine; Fleck, David E; Lee, Jing-Huei; Delbello, Melissa P (2008. )MRI brain activation in first-episode bipolar mania during a response inhibition task.Early intervention in psychiatry, ,2 (4 ),225-233

Pfeifer, Jonathan C; Welge, Jeffrey; Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P (2008. )Meta-analysis of amygdala volumes in children and adolescents with bipolar disorder.Journal of the American Academy of Child and Adolescent Psychiatry, ,47 (11 ),1289-98

Cecil, Kim M; Brubaker, Christopher J; Adler, Caleb M; Dietrich, Kim N; Altaye, Mekibib; Egelhoff, John C; Wessel, Stephanie; Elangovan, Ilayaraja; Hornung, Richard; Jarvis, Kelly; Lanphear, Bruce P (2008. )Decreased brain volume in adults with childhood lead exposure.PLoS medicine, ,5 (5 ),e112

Singh, Manpreet K; Delbello, Melissa P; Adler, Caleb M; Stanford, Kevin E; Strakowski, Stephen M (2008. )Neuroanatomical characterization of child offspring of bipolar parents.Journal of the American Academy of Child and Adolescent Psychiatry, ,47 (5 ),526-31

Patel, Nick C; DelBello, Melissa P; Cecil, Kim M; Stanford, Kevin E; Adler, Caleb M; Strakowski, Stephen M (2008. )Temporal change in N-acetyl-aspartate concentrations in adolescents with bipolar depression treated with lithium.Journal of child and adolescent psychopharmacology, ,18 (2 ),132-9

Fleck, David E; Nandagopal, Jayasree; Cerullo, Michael A; Eliassen, James C; DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M (2008. )Morphometric magnetic resonance imaging in psychiatry.Topics in magnetic resonance imaging : TMRI, ,19 (2 ),131-42

Strawn, Jeffrey R; Adler, Caleb M; Strakowski, Stephen M; DelBello, Melissa P (2008. )Hyperthermia and rhabdomyolysis in an adolescent treated with topiramate and olanzapine.Journal of child and adolescent psychopharmacology, ,18 (1 ),116-8

DiFrancesco, Mark W; Holland, Scott K; Ris, M Douglas; Adler, Caleb M; Nelson, Shannen; DelBello, Melissa P; Altaye, Mekibib; Brunner, Hermine I (2007. )Functional magnetic resonance imaging assessment of cognitive function in childhood-onset systemic lupus erythematosus: a pilot study.Arthritis and rheumatism, ,56 (12 ),4151-63

Strakowski, Stephen M; Tsai, Shang-Ying; Delbello, Melissa P; Chen, Chiao-Chicy; Fleck, David E; Adler, Caleb M; Arndt, Stephan; Amicone, Jennifer (2007. )Outcome following a first manic episode: cross-national US and Taiwan comparison.Bipolar disorders, ,9 (8 ),820-7

Cerullo, Michael A; Adler, Caleb M; Strakowski, Stephen M; Eliassen, James C; Nasrallah, Henry A; Nasrallah, Amelia T (2007. )Memantine normalizes brain activity in the inferior frontal gyrus: a controlled pilot fMRI study.Schizophrenia research, ,97 (1-3 ),294-6

Adams, John; Adler, Caleb M; Jarvis, Kelly; DelBello, Melissa P; Strakowski, Stephen M (2007. )Evidence of anterior temporal atrophy in college-level soccer players.Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, ,17 (4 ),304-6

DelBello, Melissa P; Adler, Caleb M; Whitsel, Rachel M; Stanford, Kevin E; Strakowski, Stephen M (2007. )A 12-week single-blind trial of quetiapine for the treatment of mood symptoms in adolescents at high risk for developing bipolar I disorder. The Journal of clinical psychiatry, ,68 (5 ),789-95

DelBello, Melissa P; Hanseman, Dennis; Adler, Caleb M; Fleck, David E; Strakowski, Stephen M (2007. )Twelve-month outcome of adolescents with bipolar disorder following first hospitalization for a manic or mixed episode.The American journal of psychiatry, ,164 (4 ),582-90

Adler, Caleb M; DelBello, Melissa P; Jarvis, Kelly; Levine, Ari; Adams, John; Strakowski, Stephen M (2007. )Voxel-based study of structural changes in first-episode patients with bipolar disorder.Biological psychiatry, ,61 (6 ),776-81

Singh, Manpreet K; Delbello, Melissa P; Adler, Caleb M (2007. )Acute dystonia associated with aripiprazole in a child.Journal of the American Academy of Child and Adolescent Psychiatry, ,46 (3 ),306-7

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer (2007. )Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania.Archives of general psychiatry, ,64 (1 ),57-64

Adler, Caleb M; Fleck, David E; Brecher, Martin; Strakowski, Stephen M (2007. )Safety and tolerability of quetiapine in the treatment of acute mania in bipolar disorder.Journal of affective disorders, ,100 Suppl 1 ,S15-22

Barzman, Drew H; DelBello, Melissa P; Adler, Caleb M; Stanford, Kevin E; Strakowski, Stephen M (2006. )The efficacy and tolerability of quetiapine versus divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorder(s).Journal of child and adolescent psychopharmacology, ,16 (6 ),665-70

Patel, Nick C; DelBello, Melissa P; Cecil, Kim M; Adler, Caleb M; Bryan, Holly S; Stanford, Kevin E; Strakowski, Stephen M (2006. )Lithium treatment effects on Myo-inositol in adolescents with bipolar depression.Biological psychiatry, ,60 (9 ),998-1004

DelBello, Melissa P; Cecil, Kim M; Adler, Caleb M; Daniels, John P; Strakowski, Stephen M (2006. )Neurochemical effects of olanzapine in first-hospitalization manic adolescents: a proton magnetic resonance spectroscopy study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ,31 (6 ),1264-73

Adler, Caleb M; DelBello, Melissa P; Strakowski, Stephen M (2006. )Brain network dysfunction in bipolar disorder. CNS spectrums, ,11 (4 ),312-20; quiz 323-4

DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M (2006. )The neurophysiology of childhood and adolescent bipolar disorder. CNS spectrums, ,11 (4 ),298-311

DelBello, Melissa P; Kowatch, Robert A; Adler, Caleb M; Stanford, Kevin E; Welge, Jeffrey A; Barzman, Drew H; Nelson, Erik; Strakowski, Stephen M (2006. )A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent mania.Journal of the American Academy of Child and Adolescent Psychiatry, ,45 (3 ),305-13

Patel, Nick C; DelBello, Melissa P; Bryan, Holly S; Adler, Caleb M; Kowatch, Robert A; Stanford, Kevin; Strakowski, Stephen M (2006. )Open-label lithium for the treatment of adolescents with bipolar depression.Journal of the American Academy of Child and Adolescent Psychiatry, ,45 (3 ),289-97

Adler, Caleb M; Adams, John; DelBello, Melissa P; Holland, Scott K; Schmithorst, Vince; Levine, Ari; Jarvis, Kelly; Strakowski, Stephen M (2006. )Evidence of white matter pathology in bipolar disorder adolescents experiencing their first episode of mania: a diffusion tensor imaging study.The American journal of psychiatry, ,163 (2 ),322-4

Weinstein, Shannon K; Adler, Caleb M; Strakowski, Stephen M (2006. )Ziprasidone-induced acute dystonic reactions in patients with bipolar disorder. The Journal of clinical psychiatry, ,67 (2 ),327-8

Adler, Caleb M; Delbello, Melissa P; Mills, Neil P; Schmithorst, Vince; Holland, Scott; Strakowski, Stephen M (2005. )Comorbid ADHD is associated with altered patterns of neuronal activation in adolescents with bipolar disorder performing a simple attention task.Bipolar disorders, ,7 (6 ),577-88

Strakowski, Stephen M; Adler, Caleb M; Holland, Scott K; Mills, Neil P; DelBello, Melissa P; Eliassen, James C (2005. )Abnormal FMRI brain activation in euthymic bipolar disorder patients during a counting Stroop interference task.The American journal of psychiatry, ,162 (9 ),1697-705

Mills, Neil P; Delbello, Melissa P; Adler, Caleb M; Strakowski, Stephen M (2005. )MRI analysis of cerebellar vermal abnormalities in bipolar disorder.The American journal of psychiatry, ,162 (8 ),1530-2

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer (2005. )Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania.Archives of general psychiatry, ,62 (8 ),851-8

Adler, Caleb M; Levine, Ari D; DelBello, Melissa P; Strakowski, Stephen M (2005. )Changes in gray matter volume in patients with bipolar disorder.Biological psychiatry, ,58 (2 ),151-7

Strakowski, S M; Delbello, M P; Adler, C M (2005. )The functional neuroanatomy of bipolar disorder: a review of neuroimaging findings.Molecular psychiatry, ,10 (1 ),105-16

Adler, Caleb M; Holland, Scott K; Schmithorst, Vince; Tuchfarber, Michael J; Strakowski, Stephen M (2004. )Changes in neuronal activation in patients with bipolar disorder during performance of a working memory task.Bipolar disorders, ,6 (6 ),540-9

DelBello, Melissa P; Adler, Caleb M; Amicone, Jennifer; Mills, Neil P; Shear, Paula K; Warner, Juliet; Strakowski, Stephen M (2004. )Parametric neurocognitive task design: a pilot study of sustained attention in adolescents with bipolar disorder.Journal of affective disorders, ,82 Suppl 1 ,S79-88

Strakowski, Stephen M; Adler, Caleb M; Holland, Scott K; Mills, Neil; DelBello, Melissa P (2004. )A preliminary FMRI study of sustained attention in euthymic, unmedicated bipolar disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ,29 (9 ),1734-40

Adler, Caleb M; Holland, Scott K; Schmithorst, Vince; Wilke, Marko; Weiss, Kenneth L; Pan, Hai; Strakowski, Stephen M (2004. )Abnormal frontal white matter tracts in bipolar disorder: a diffusion tensor imaging study.Bipolar disorders, ,6 (3 ),197-203

Strakowski, Stephen M; Del Bello, Melissa P; Adler, Caleb M; Keck, Paul E (2003. )Atypical antipsychotics in the treatment of bipolar disorder.Expert opinion on pharmacotherapy, ,4 (5 ),751-60

Adler, Caleb M; Strakowski, Stephen M (2003. )Boundaries of schizophrenia. The Psychiatric clinics of North America, ,26 (1 ),1-23

Strakowski, Stephen M; DelBello, Melissa P; Zimmerman, Molly E; Getz, Glen E; Mills, Neil P; Ret, Jennifer; Shear, Paula; Adler, Caleb M (2002. )Ventricular and periventricular structural volumes in first- versus multiple-episode bipolar disorder. The American journal of psychiatry, ,159 (11 ),1841-7

Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P (2002. )Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder? .Bipolar disorders, ,4 (2 ),80-8

Adler, Caleb M; Malhotra, Anil K; Elman, Igor; Pickar, David; Breier, Alan (2002. )Amphetamine-induced dopamine release and post-synaptic specific binding in patients with mild tardive dyskinesia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ,26 (3 ),295-300

Adler, C M; Sax, K W; Holland, S K; Schmithorst, V; Rosenberg, L; Strakowski, S M (2001. )Changes in neuronal activation with increasing attention demand in healthy volunteers: an fMRI study.Synapse (New York, N.Y.), ,42 (4 ),266-72

Adler, C M; Holland, S K; Enseleit, S; Strakowski, S M (2001. )Age-related changes in regional activation during working memory in young adults: an fMRI study.Synapse (New York, N.Y.), ,42 (4 ),252-7

Strakowski, S M; Sax, K W; Rosenberg, H L; DelBello, M P; Adler, C M (2001. )Human response to repeated low-dose d-amphetamine: evidence for behavioral enhancement and tolerance.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ,25 (4 ),548-54

Elman, I; Goldstein, D S; Adler, C M; Shoaf, S E; Breier, A (2001. )Inverse relationship between plasma epinephrine and testosterone levels during acute glucoprivation in healthy men. Life sciences, ,68 (16 ),1889-98

Strakowski, S M; DelBello, M P; Adler, C M (2001. )Comparative efficacy and tolerability of drug treatments for bipolar disorder. CNS drugs, ,15 (9 ),701-18

Adler, C M; McDonough-Ryan, P; Sax, K W; Holland, S K; Arndt, S; Strakowski, S M fMRI of neuronal activation with symptom provocation in unmedicated patients with obsessive compulsive disorder. Journal of psychiatric research, ,34 (4-5 ),317-24

Adler, C M; Elman, I; Weisenfeld, N; Kestler, L; Pickar, D; Breier, A (2000. )Effects of acute metabolic stress on striatal dopamine release in healthy volunteers.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ,22 (5 ),545-50

Adler, C M; Malhotra, A K; Elman, I; Goldberg, T; Egan, M; Pickar, D; Breier, A (1999. )Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia. The American journal of psychiatry, ,156 (10 ),1646-9

Breier, A; Su, T P; Malhotra, A K; Elman, I; Adler, C M; Weisenfeld, N I; Pickar, D (1999. )Effects of atypical antipsychotic drug treatment on amphetamine-induced striatal dopamine release in patients with psychotic disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ,20 (4 ),340-5

Breier, A F; Malhotra, A K; Su, T P; Pinals, D A; Elman, I; Adler, C M; Lafargue, R T; Clifton, A; Pickar, D (1999. )Clozapine and risperidone in chronic schizophrenia: effects on symptoms, parkinsonian side effects, and neuroendocrine response. The American journal of psychiatry, ,156 (2 ),294-8

Elman, I; Sokoloff, L; Adler, C M; Weisenfeld, N; Breier, A (1999. )The effects of pharmacological doses of 2-deoxyglucose on cerebral blood flow in healthy volunteers. Brain research, ,815 (2 ),243-9

Elman, I; Goldstein, D S; Eisenhofer, G; Folio, J; Malhotra, A K; Adler, C M; Pickar, D; Breier, A (1999. )Mechanism of peripheral noradrenergic stimulation by clozapine.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ,20 (1 ),29-34

Elman, I; Adler, C M; Malhotra, A K; Bir, C; Pickar, D; Breier, A (1998. )Effect of acute metabolic stress on pituitary-adrenal axis activation in patients with schizophrenia. The American journal of psychiatry, ,155 (7 ),979-81

Adler, C M; Goldberg, T E; Malhotra, A K; Pickar, D; Breier, A (1998. )Effects of ketamine on thought disorder, working memory, and semantic memory in healthy volunteers. Biological psychiatry, ,43 (11 ),811-6

Breier, A; Adler, C M; Weisenfeld, N; Su, T P; Elman, I; Picken, L; Malhotra, A K; Pickar, D (1998. )Effects of NMDA antagonism on striatal dopamine release in healthy subjects: application of a novel PET approach.Synapse (New York, N.Y.), ,29 (2 ),142-7

Malhotra, A K; Adler, C M; Kennison, S D; Elman, I; Pickar, D; Breier, A (1997. )Clozapine blunts N-methyl-D-aspartate antagonist-induced psychosis: a study with ketamine. Biological psychiatry, ,42 (8 ),664-8

Malhotra, A K; Pinals, D A; Adler, C M; Elman, I; Clifton, A; Pickar, D; Breier, A (1997. )Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ,17 (3 ),141-50

Adler, C M; Craske, M G; Kirshenbaum, S; Barlow, D H (1989. )'Fear of panic': an investigation of its role in panic occurrence, phobic avoidance, and treatment outcome. Behaviour research and therapy, ,27 (4 ),391-6

Dudley, Jonathan; DelBello, Melissa P; Weber, Wade A; Adler, Caleb M; Strakowski, Stephen M; Lee, Jing-Huei (2016. )Tissue-dependent cerebral energy metabolism in adolescents with bipolar disorder.Journal of affective disorders, ,191 ,248-55

McNamara, Robert K; Jandacek, Ronald; Tso, Patrick; Blom, Thomas J; Welge, Jeffrey A; Strawn, Jeffrey R; Adler, Caleb M; DelBello, Melissa P; Strakowski, Stephen M (2015. )First-episode bipolar disorder is associated with erythrocyte membrane docosahexaenoic acid deficits: Dissociation from clinical response to lithium or quetiapine.Psychiatry research, ,230 (2 ),447-53

McNamara, Robert K; Jandacek, Ronald; Tso, Patrick; Blom, Thomas J; Welge, Jeffrey A; Strawn, Jeffrey R; Adler, Caleb M; Strakowski, Stephen M; DelBello, Melissa P (2015. )Adolescents with or at ultra-high risk for bipolar disorder exhibit erythrocyte docosahexaenoic acid and eicosapentaenoic acid deficits: a candidate prodromal risk biomarker.Early intervention in psychiatry, ,

Davis, Andrew K; DelBello, Melissa P; Eliassen, James; Welge, Jeffrey; Blom, Thomas J; Fleck, David E; Weber, Wade A; Jarvis, Kelly B; Rummelhoff, Emily; Strakowski, Stephen M; Adler, Caleb M (2015. )Neurofunctional effects of quetiapine in patients with bipolar mania.Bipolar disorders, ,17 (4 ),444-9

Wehry, Anna M; McNamara, Robert K; Adler, Caleb M; Eliassen, James C; Croarkin, Paul; Cerullo, Michael A; DelBello, Melissa P; Strawn, Jeffrey R (2015. )Neurostructural impact of co-occurring anxiety in pediatric patients with major depressive disorder: a voxel-based morphometry study.Journal of affective disorders, ,171 ,54-9

Dawson, Erica L; Shear, Paula K; Howe, Steven R; Adler, Caleb M; DelBello, Melissa P; Fleck, David E; Strakowski, Stephen M (2014. )Impulsivity predicts time to reach euthymia in adults with bipolar disorder.Bipolar disorders, ,16 (8 ),846-56

Bitter, Samantha M; Adler, Caleb M; Eliassen, James C; Weber, Wade A; Welge, Jeffrey A; Burciaga, Joaquin; Shear, Paula K; Strakowski, Stephen M; DelBello, Melissa P (2014. )Neurofunctional changes in adolescent cannabis users with and without bipolar disorder.Addiction (Abingdon, England), ,109 (11 ),1901-9

Cerullo, Michael A; Eliassen, James C; Smith, Christopher T; Fleck, David E; Nelson, Erik B; Strawn, Jeffrey R; Lamy, Martine; DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M (2014. )Bipolar I disorder and major depressive disorder show similar brain activation during depression.Bipolar disorders, ,16 (7 ),703-12

Strawn, Jeffrey R; John Wegman, C; Dominick, Kelli C; Swartz, Max S; Wehry, Anna M; Patino, Luis R; Strakowski, Stephen M; Adler, Caleb M; Eliassen, James C; DelBello, Melissa P (2014. )Cortical surface anatomy in pediatric patients with generalized anxiety disorder.Journal of anxiety disorders, ,28 (7 ),717-23

Schneider, Marguerite Reid; Klein, Christina C; Weber, Wade; Bitter, Samantha M; Elliott, Kimberly B; Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P (2014. )The effects of carbamazepine on prefrontal activation in manic youth with bipolar disorder.Psychiatry research, ,223 (3 ),268-70

Strawn, Jeffrey R; Adler, Caleb M; McNamara, Robert K; Welge, Jeffrey A; Bitter, Samantha M; Mills, Neil P; Barzman, Drew H; Cerullo, Michael A; Chang, Kiki D; Strakowski, Stephen M; DelBello, Melissa P (2014. )Antidepressant tolerability in anxious and depressed youth at high risk for bipolar disorder: a prospective naturalistic treatment study.Bipolar disorders, ,16 (5 ),523-30

Stephens, Jacob R; Heffner, Jaimee L; Adler, Caleb M; Blom, Thomas J; Anthenelli, Robert M; Fleck, David E; Welge, Jeffrey A; Strakowski, Stephen M; DelBello, Melissa P (2014. )Risk and protective factors associated with substance use disorders in adolescents with first-episode mania.Journal of the American Academy of Child and Adolescent Psychiatry, ,53 (7 ),771-9

McNamara, Robert K; Jandacek, Ronald; Rider, Therese; Tso, Patrick; Chu, Wen-Jang; Weber, Wade A; Welge, Jeffrey A; Strawn, Jeffrey R; Adler, Caleb M; DelBello, Melissa P (2014. )Effects of fish oil supplementation on prefrontal metabolite concentrations in adolescents with major depressive disorder: A preliminary (1)H MRS study.Nutritional neuroscience, ,

Bitter, Samantha M; Weber, Wade A; Chu, Wen-Jang; Adler, Caleb M; Eliassen, James C; Strakowski, Stephen M; DelBello, Melissa P (2014. )N-acetyl aspartate levels in adolescents with bipolar and/or cannabis use disorders.Journal of dual diagnosis, ,10 (1 ),39-43

Heffner, Jaimee L; Anthenelli, Robert M; Adler, Caleb M; Strakowski, Stephen M; Beavers, Jennifer; DelBello, Melissa P (2013. )Prevalence and correlates of heavy smoking and nicotine dependence in adolescents with bipolar and cannabis use disorders.Psychiatry research, ,210 (3 ),857-62

Chu, Wen-Jang; Delbello, Melissa P; Jarvis, Kelly B; Norris, Mathew M; Kim, Mi-Jung; Weber, Wade; Lee, Jing-Huei; Strakowski, Stephen M; Adler, Caleb M (2013. )Magnetic resonance spectroscopy imaging of lactate in patients with bipolar disorder.Psychiatry research, ,213 (3 ),230-4

Weber, Wade A; Dudley, Jonathan; Lee, Jing-Huei; Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P (2013. )A pilot study of alterations in high energy phosphoryl compounds and intracellular pH in unmedicated adolescents with bipolar disorder.Journal of affective disorders, ,150 (3 ),1109-13

Strakowski, Stephen M; Adler, Caleb M; Delbello, Melissa P (2013. )Is depression simply a nonspecific response to brain injury?.Current psychiatry reports, ,15 (9 ),386

Strawn, Jeffrey R; Wehry, Anna M; Chu, Wen-Jang; Adler, Caleb M; Eliassen, James C; Cerullo, Michael A; Strakowski, Stephen M; Delbello, Melissa P (2013. )Neuroanatomic abnormalities in adolescents with generalized anxiety disorder: a voxel-based morphometry study.Depression and anxiety, ,30 (9 ),842-8

Adler, Caleb M; DelBello, Melissa P; Weber, Wade A; Jarvis, Kelly B; Welge, Jeffrey; Chu, Wen-Jang; Rummelhoff, Emily; Kim, Mi-Jung; Lee, Jing-Huei; Strakowski, Stephen M (2013. )Neurochemical effects of quetiapine in patients with bipolar mania: a proton magnetic resonance spectroscopy study.Journal of clinical psychopharmacology, ,33 (4 ),528-32

McNamara, Robert K; Jandacek, Ronald; Tso, Patrick; Weber, Wade; Chu, Wen-Jang; Strakowski, Stephen M; Adler, Caleb M; Delbello, Melissa P (2013. )Low docosahexaenoic acid status is associated with reduced indices in cortical integrity in the anterior cingulate of healthy male children: a 1H MRS Study.Nutritional neuroscience, ,16 (4 ),183-90

Patino, Luis R; Adler, Caleb M; Mills, Neil P; Strakowski, Stephen M; Fleck, David E; Welge, Jeffrey A; DelBello, Melissa P (2013. )Conflict monitoring and adaptation in individuals at familial risk for developing bipolar disorder.Bipolar disorders, ,15 (3 ),264-71

Southammakosane, C; Danielyan, A; Welge, J A; Blom, T J; Adler, C M; Chang, K D; Howe, M; DelBello, M P (2013. )Characteristics of the child behavior checklist in adolescents with depression associated with bipolar disorder.Journal of affective disorders, ,145 (3 ),405-8

Strawn, Jeffrey R; Chu, Wen-Jang; Whitsel, Rachel M; Weber, Wade A; Norris, Matthew M; Adler, Caleb M; Eliassen, James C; Phan, K Luan; Strakowski, Stephen M; DelBello, Melissa P (2013. )A pilot study of anterior cingulate cortex neurochemistry in adolescents with generalized anxiety disorder.Neuropsychobiology, ,67 (4 ),224-9

Heffner, Jaimee L; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Strakowski, Stephen M (2012. )Unplanned pregnancies in adolescents with bipolar disorder.The American journal of psychiatry, ,169 (12 ),1319

Heffner, Jaimee L; Fleck, David E; DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M (2012. )Cigarette smoking and impulsivity in bipolar disorder.Bipolar disorders, ,14 (7 ),735-42

Schneider, Marguerite Reid; DelBello, Melissa P; McNamara, Robert K; Strakowski, Stephen M; Adler, Caleb M (2012. )Neuroprogression in bipolar disorder.Bipolar disorders, ,14 (4 ),356-74

Strakowski, Stephen M; Adler, Caleb M; Almeida, Jorge; Altshuler, Lori L; Blumberg, Hilary P; Chang, Kiki D; DelBello, Melissa P; Frangou, Sophia; McIntosh, Andrew; Phillips, Mary L; Sussman, Jessika E; Townsend, Jennifer D (2012. )The functional neuroanatomy of bipolar disorder: a consensus model.Bipolar disorders, ,14 (4 ),313-25

Strawn, Jeffrey R; Patel, Nick C; Chu, Wen-Jang; Lee, Jing-Huei; Adler, Caleb M; Kim, Mi Jung; Bryan, Holly S; Alfieri, David C; Welge, Jeffrey A; Blom, Thomas J; Nandagopal, Jayasree J; Strakowski, Stephen M; DelBello, Melissa P (2012. )Glutamatergic effects of divalproex in adolescents with mania: a proton magnetic resonance spectroscopy study.Journal of the American Academy of Child and Adolescent Psychiatry, ,51 (6 ),642-51

Cerullo, Michael A; Fleck, David E; Eliassen, James C; Smith, Matt S; DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M (2012. )A longitudinal functional connectivity analysis of the amygdala in bipolar I disorder across mood states.Bipolar disorders, ,14 (2 ),175-84

Fleck, D E; Eliassen, J C; Durling, M; Lamy, M; Adler, C M; DelBello, M P; Shear, P K; Cerullo, M A; Lee, J-H; Strakowski, S M (2012. )Functional MRI of sustained attention in bipolar mania.Molecular psychiatry, ,17 (3 ),325-36

Heffner, Jaimee L; DelBello, Melissa P; Anthenelli, Robert M; Fleck, David E; Adler, Caleb M; Strakowski, Stephen M (2012. )Cigarette smoking and its relationship to mood disorder symptoms and co-occurring alcohol and cannabis use disorders following first hospitalization for bipolar disorder.Bipolar disorders, ,14 (1 ),99-108

Schneider, Marguerite Reid; Adler, Caleb M; Whitsel, Rachel; Weber, Wade; Mills, Neil P; Bitter, Samantha M; Eliassen, James; Strakowski, Stephen M; DelBello, Melissa P (2012. )The effects of ziprasidone on prefrontal and amygdalar activation in manic youth with bipolar disorder. The Israel journal of psychiatry and related sciences, ,49 (2 ),112-20

Macfadden, Wayne; Adler, Caleb M; Turkoz, Ibrahim; Haskins, John T; Turner, Norris; Alphs, Larry (2011. )Adjunctive long-acting risperidone in patients with bipolar disorder who relapse frequently and have active mood symptoms.BMC psychiatry, ,11 ,171

Bitter, Samantha M; Mills, Neil P; Adler, Caleb M; Strakowski, Stephen M; DelBello, Melissa P (2011. )Progression of amygdala volumetric abnormalities in adolescents after their first manic episode.Journal of the American Academy of Child and Adolescent Psychiatry, ,50 (10 ),1017-26

Nandagopal, Jayasree J; Fleck, David E; Adler, Caleb M; Mills, Neil P; Strakowski, Stephen M; DelBello, Melissa P (2011. )Impulsivity in adolescents with bipolar disorder and/or attention-deficit/hyperactivity disorder and healthy controls as measured by the Barratt Impulsiveness Scale.Journal of child and adolescent psychopharmacology, ,21 (5 ),465-8

Fleck, David E; Kotwal, Renu; Eliassen, James C; Lamy, Martine; Delbello, Melissa P; Adler, Caleb M; Durling, Michelle; Cerullo, Michael A; Strakowski, Stephen M (2011. )Preliminary evidence for increased frontosubcortical activation on a motor impulsivity task in mixed episode bipolar disorder.Journal of affective disorders, ,133 (1-2 ),333-9

Lisy, Megan E; Jarvis, Kelly B; DelBello, Melissa P; Mills, Neil P; Weber, Wade A; Fleck, David; Strakowski, Stephen M; Adler, Caleb M (2011. )Progressive neurostructural changes in adolescent and adult patients with bipolar disorder.Bipolar disorders, ,13 (4 ),396-405

Strakowski, Stephen M; Eliassen, James C; Lamy, Martine; Cerullo, Michael A; Allendorfer, Jane B; Madore, Michelle; Lee, Jing-Huei; Welge, Jeffrey A; DelBello, Melissa P; Fleck, David E; Adler, Caleb M (2011. )Functional magnetic resonance imaging brain activation in bipolar mania: evidence for disruption of the ventrolateral prefrontal-amygdala emotional pathway.Biological psychiatry, ,69 (4 ),381-8

Strakowski, Stephen M; Fleck, David E; DelBello, Melissa P; Adler, Caleb M; Shear, Paula K; Kotwal, Renu; Arndt, Stephan (2010. )Impulsivity across the course of bipolar disorder.Bipolar disorders, ,12 (3 ),285-97

Strawn, Jeffrey R; Adler, Caleb M; Fleck, David E; Hanseman, Dennis; Maue, Danielle K; Bitter, Samantha; Kraft, Elizabeth M; Geracioti, Thomas D; Strakowski, Stephen M; DelBello, Melissa P (2010. )Post-traumatic stress symptoms and trauma exposure in youth with first episode bipolar disorder.Early intervention in psychiatry, ,4 (2 ),169-73

McNamara, Robert K; Able, Jessica; Jandacek, Ronald; Rider, Therese; Tso, Patrick; Eliassen, James C; Alfieri, David; Weber, Wade; Jarvis, Kelly; DelBello, Melissa P; Strakowski, Stephen M; Adler, Caleb M (2010. )Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging, functional magnetic resonance imaging study.The American journal of clinical nutrition, ,91 (4 ),1060-7

DelBello, Melissa P; Chang, Kiki; Welge, Jeffrey A; Adler, Caleb M; Rana, Manasi; Howe, Meghan; Bryan, Holly; Vogel, Daniel; Sampang, Suzanne; Delgado, Sergio V; Sorter, Michael; Strakowski, Stephen M (2009. )A double-blind, placebo-controlled pilot study of quetiapine for depressed adolescents with bipolar disorder.Bipolar disorders, ,11 (5 ),483-93

Cerullo, Michael A; Adler, Caleb M; Lamy, Martine; Eliassen, James C; Fleck, David E; Strakowski, Stephen M; DelBello, Melissa P (2009. )Differential brain activation during response inhibition in bipolar and attention-deficit hyperactivity disorders.Early intervention in psychiatry, ,3 (3 ),189-97

Strakowski, Stephen M; Fleck, David E; DelBello, Melissa P; Adler, Caleb M; Shear, Paula K; McElroy, Susan L; Keck, Paul E; Moss, Quinton; Cerullo, Michael A; Kotwal, Renu; Arndt, Stephan (2009. )Characterizing impulsivity in mania.Bipolar disorders, ,11 (1 ),41-51

Cerullo, Michael A; Adler, Caleb M; Delbello, Melissa P; Strakowski, Stephen M (2009. )The functional neuroanatomy of bipolar disorder.International review of psychiatry (Abingdon, England), ,21 (4 ),314-22

Patel, Nick C; Cecil, Kim M; Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P (2008. )Neurochemical alterations in adolescent bipolar depression: a proton magnetic resonance spectroscopy pilot study of the prefrontal cortex.Journal of child and adolescent psychopharmacology, ,18 (6 ),623-7

Jarvis, Kelly; DelBello, Melissa P; Mills, Neil; Elman, Igor; Strakowski, Stephen M; Adler, Caleb M (2008. )Neuroanatomic comparison of bipolar adolescents with and without cannabis use disorders.Journal of child and adolescent psychopharmacology, ,18 (6 ),557-63

Strakowski, Stephen M; Adler, Caleb M; Cerullo, Michael A; Eliassen, James C; Lamy, Martine; Fleck, David E; Lee, Jing-Huei; DelBello, Melissa P (2008. )Magnetic resonance imaging brain activation in first-episode bipolar mania during a response inhibition task.Early intervention in psychiatry, ,2 (4 ),225-33

Pfeifer, Jonathan C; Welge, Jeffrey; Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P (2008. )Meta-analysis of amygdala volumes in children and adolescents with bipolar disorder.Journal of the American Academy of Child and Adolescent Psychiatry, ,47 (11 ),1289-98

Singh, Manpreet K; Delbello, Melissa P; Adler, Caleb M; Stanford, Kevin E; Strakowski, Stephen M (2008. )Neuroanatomical characterization of child offspring of bipolar parents.Journal of the American Academy of Child and Adolescent Psychiatry, ,47 (5 ),526-31

Patel, Nick C; DelBello, Melissa P; Cecil, Kim M; Stanford, Kevin E; Adler, Caleb M; Strakowski, Stephen M (2008. )Temporal change in N-acetyl-aspartate concentrations in adolescents with bipolar depression treated with lithium.Journal of child and adolescent psychopharmacology, ,18 (2 ),132-9

Fleck, David E; Nandagopal, Jayasree; Cerullo, Michael A; Eliassen, James C; DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M (2008. )Morphometric magnetic resonance imaging in psychiatry.Topics in magnetic resonance imaging : TMRI, ,19 (2 ),131-42

Strawn, Jeffrey R; Adler, Caleb M; Strakowski, Stephen M; DelBello, Melissa P (2008. )Hyperthermia and rhabdomyolysis in an adolescent treated with topiramate and olanzapine.Journal of child and adolescent psychopharmacology, ,18 (1 ),116-8

DiFrancesco, Mark W; Holland, Scott K; Ris, M Douglas; Adler, Caleb M; Nelson, Shannen; DelBello, Melissa P; Altaye, Mekibib; Brunner, Hermine I (2007. )Functional magnetic resonance imaging assessment of cognitive function in childhood-onset systemic lupus erythematosus: a pilot study.Arthritis and rheumatism, ,56 (12 ),4151-63

Strakowski, Stephen M; Tsai, Shang-Ying; Delbello, Melissa P; Chen, Chiao-Chicy; Fleck, David E; Adler, Caleb M; Arndt, Stephan; Amicone, Jennifer (2007. )Outcome following a first manic episode: cross-national US and Taiwan comparison.Bipolar disorders, ,9 (8 ),820-7

Adams, John; Adler, Caleb M; Jarvis, Kelly; DelBello, Melissa P; Strakowski, Stephen M (2007. )Evidence of anterior temporal atrophy in college-level soccer players.Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, ,17 (4 ),304-6

DelBello, Melissa P; Adler, Caleb M; Whitsel, Rachel M; Stanford, Kevin E; Strakowski, Stephen M (2007. )A 12-week single-blind trial of quetiapine for the treatment of mood symptoms in adolescents at high risk for developing bipolar I disorder. The Journal of clinical psychiatry, ,68 (5 ),789-95

DelBello, Melissa P; Hanseman, Dennis; Adler, Caleb M; Fleck, David E; Strakowski, Stephen M (2007. )Twelve-month outcome of adolescents with bipolar disorder following first hospitalization for a manic or mixed episode.The American journal of psychiatry, ,164 (4 ),582-90

Adler, Caleb M; DelBello, Melissa P; Jarvis, Kelly; Levine, Ari; Adams, John; Strakowski, Stephen M (2007. )Voxel-based study of structural changes in first-episode patients with bipolar disorder.Biological psychiatry, ,61 (6 ),776-81

Singh, Manpreet K; Delbello, Melissa P; Adler, Caleb M (2007. )Acute dystonia associated with aripiprazole in a child.Journal of the American Academy of Child and Adolescent Psychiatry, ,46 (3 ),306-7

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer (2007. )Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania.Archives of general psychiatry, ,64 (1 ),57-64

Barzman, Drew H; DelBello, Melissa P; Adler, Caleb M; Stanford, Kevin E; Strakowski, Stephen M (2006. )The efficacy and tolerability of quetiapine versus divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorder(s).Journal of child and adolescent psychopharmacology, ,16 (6 ),665-70

Patel, Nick C; DelBello, Melissa P; Cecil, Kim M; Adler, Caleb M; Bryan, Holly S; Stanford, Kevin E; Strakowski, Stephen M (2006. )Lithium treatment effects on Myo-inositol in adolescents with bipolar depression.Biological psychiatry, ,60 (9 ),998-1004

DelBello, Melissa P; Cecil, Kim M; Adler, Caleb M; Daniels, John P; Strakowski, Stephen M (2006. )Neurochemical effects of olanzapine in first-hospitalization manic adolescents: a proton magnetic resonance spectroscopy study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ,31 (6 ),1264-73

Adler, Caleb M; DelBello, Melissa P; Strakowski, Stephen M (2006. )Brain network dysfunction in bipolar disorder. CNS spectrums, ,11 (4 ),312-20; quiz 323-4

DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M (2006. )The neurophysiology of childhood and adolescent bipolar disorder. CNS spectrums, ,11 (4 ),298-311

DelBello, Melissa P; Kowatch, Robert A; Adler, Caleb M; Stanford, Kevin E; Welge, Jeffrey A; Barzman, Drew H; Nelson, Erik; Strakowski, Stephen M (2006. )A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent mania.Journal of the American Academy of Child and Adolescent Psychiatry, ,45 (3 ),305-13

Patel, Nick C; DelBello, Melissa P; Bryan, Holly S; Adler, Caleb M; Kowatch, Robert A; Stanford, Kevin; Strakowski, Stephen M (2006. )Open-label lithium for the treatment of adolescents with bipolar depression.Journal of the American Academy of Child and Adolescent Psychiatry, ,45 (3 ),289-97

Adler, Caleb M; Adams, John; DelBello, Melissa P; Holland, Scott K; Schmithorst, Vince; Levine, Ari; Jarvis, Kelly; Strakowski, Stephen M (2006. )Evidence of white matter pathology in bipolar disorder adolescents experiencing their first episode of mania: a diffusion tensor imaging study.The American journal of psychiatry, ,163 (2 ),322-4

Adler, Caleb M; Delbello, Melissa P; Mills, Neil P; Schmithorst, Vince; Holland, Scott; Strakowski, Stephen M (2005. )Comorbid ADHD is associated with altered patterns of neuronal activation in adolescents with bipolar disorder performing a simple attention task.Bipolar disorders, ,7 (6 ),577-88

Strakowski, Stephen M; Adler, Caleb M; Holland, Scott K; Mills, Neil P; DelBello, Melissa P; Eliassen, James C (2005. )Abnormal FMRI brain activation in euthymic bipolar disorder patients during a counting Stroop interference task.The American journal of psychiatry, ,162 (9 ),1697-705

Mills, Neil P; Delbello, Melissa P; Adler, Caleb M; Strakowski, Stephen M (2005. )MRI analysis of cerebellar vermal abnormalities in bipolar disorder.The American journal of psychiatry, ,162 (8 ),1530-2

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer (2005. )Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania.Archives of general psychiatry, ,62 (8 ),851-8

Adler, Caleb M; Levine, Ari D; DelBello, Melissa P; Strakowski, Stephen M (2005. )Changes in gray matter volume in patients with bipolar disorder.Biological psychiatry, ,58 (2 ),151-7

Hopper, J W; Karlsgodt, K H; Adler, C M; Macklin, E A; Lukas, S E; Elman, I (2004. )Effects of acute cortisol and cocaine administration on attention, recall and recognition task performance in individuals with cocaine dependence.Human psychopharmacology, ,19 (7 ),511-6

DelBello, Melissa P; Adler, Caleb M; Amicone, Jennifer; Mills, Neil P; Shear, Paula K; Warner, Juliet; Strakowski, Stephen M (2004. )Parametric neurocognitive task design: a pilot study of sustained attention in adolescents with bipolar disorder.Journal of affective disorders, ,82 Suppl 1 ,S79-88

Strakowski, Stephen M; Adler, Caleb M; Holland, Scott K; Mills, Neil; DelBello, Melissa P (2004. )A preliminary FMRI study of sustained attention in euthymic, unmedicated bipolar disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, ,29 (9 ),1734-40

Strakowski, Stephen M; DelBello, Melissa P; Zimmerman, Molly E; Getz, Glen E; Mills, Neil P; Ret, Jennifer; Shear, Paula; Adler, Caleb M (2002. )Ventricular and periventricular structural volumes in first- versus multiple-episode bipolar disorder.The American journal of psychiatry, ,159 (11 ),1841-7

Strakowski, Stephen M; Adler, Caleb M; DelBello, Melissa P (2002. )Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder? .Bipolar disorders, ,4 (2 ),80-8

Hillhouse, J J; Adler, C M (1997. )Investigating stress effect patterns in hospital staff nurses: results of a cluster analysis. Social science & medicine (1982), ,45 (12 ),1781-8

Hillhouse, J J; Adler, C M; Drinnon, J; Turrisi, R (1997. )Application of Azjen's theory of planned behavior to predict sunbathing, tanning salon use, and sunscreen use intentions and behaviors. Journal of behavioral medicine, ,20 (4 ),365-78

Hillhouse, J J; Stair, A W; Adler, C M (1996. )Predictors of sunbathing and sunscreen use in college undergraduates. Journal of behavioral medicine, ,19 (6 ),543-61

Scouten, W H; Adler, C M; Rongen, R; Mallee, L (1992. )Evaluation of the mode of binding of immunoglobulin to activated agarose. Journal of chromatography, ,597 (1-2 ),231-8

Rongen, R M; Adler, C M; Scouten, W H (1991. )S-Zephyr, a new high performance ion exchange chromatography column matrix. Bioseparation, ,2 (5 ),297-308

Dehm, E J; Puliafito, C A; Adler, C M; Steinert, R F (1986. )Corneal endothelial injury in rabbits following excimer laser ablation at 193 and 248 nm. Archives of ophthalmology (Chicago, Ill. : 1960), ,104 (9 ),1364-8

Puliafito, C A; Steinert, R F; Deutsch, T F; Hillenkamp, F; Dehm, E J; Adler, C M (1985. )Excimer laser ablation of the cornea and lens. Experimental studies. Ophthalmology, ,92 (6 ),741-8

Numan, R; Naparzewska, A M; Adler, C M (1984. )Absence of reinforcement with low dose intravenous ethanol self-administration in rats. Pharmacology, biochemistry, and behavior, ,21 (4 ),609-15

Honors and Awards

Lilly Fellowship Award, Society of Biological Psychiatry

Young Investigators Research Colloquium, American Psychiatric Association (twice)

Fellows Award for Research Excellence in Psychiatry (twice)

National Instututes of Health; Bristol-Myers Squibb Travel Award

American College of Neuropsychophamaology, Selected to Future Leaders in Psychiatry

Young Investigator Travel Award, International Congress for Schizophrenia Research

James A. Bain Travel Award, American Society for Pharmacology and Experimental Therapeutics

Other Information

Cal Adler, MD, is a physician with University of Cincinnati Physicians.

Practice Location:
Stetson Building
260 Stetson Street, Suite 3200
Cincinnati, OH  45219

Clinical Specialties:
Psychiatry/Psychology, Mood Disorders, Bipolar Disorder

To make an appointment, please call (513) 475-8000.


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Contact Information

Academic - Stenson Building
Suite 3200
Cincinnati  Ohio, 45219
Phone: 513-558-7700
caleb.adler@uc.edu