Hassane Amlal

Hassane Amlal

Research Associate Professor of Medicine

Medical Sciences Building

6116

COM IM NEP Amlal Lab - 0585

University of Cincinnati College of Medicine
Room 6116
Cincinnati, Ohio 45267

Education

Bachelor's Degree, University Cadi Ayyad 1989 (Animal Biology)

Certificate of Physiology, University of Nancy I Nancy, France, 1989

Master's Degree, University Pierre et Marie Curie (Paris 6) 1990 (Renal Physiology and Pathophysiology)

Doctoral Degree, University Pierre et Marie Curie (Paris 6) 1994 (Renal Physiology)

Positions and Work Experience

07-1999 -09-2011 Research Assistant Professor of Medicine, Department of Internal Medicine, Division of Nephrology and Hypertension, University of Cincinnati, Cincinnati, OH

09-2011 -To Present Research Associate Professor of Medicine, Department of Internal Medicine Division of Nephrology and Hypertension, University of Cincinnati, Cincinnati, OH

Research and Practice Interests

Molecular and Functional Regulation of Renal Epithelial Salt, Water and Acid-Based Transporters in Health and Disease

Research Support

Grant: #1R01DK083582 Investigators:Hassane Amlal 08-01-2010 -07-31-2015 R01/NIH/NIDDK Regulation of incorganic phosphate metabolism by estrogen Role:PI Type:Grant

Investigators:M Soleimani, H Amlal 04-01-2006 -05-31-2011 Veterans Administration, Merit Review Award SLC26A7, a Basolateral Chloride/Bicarbonate Exchanger in Kidney OMCD Role:Co-Investigator

Grant: #1 R01 DK62809-01A1 Investigators:M Soleimani, H Amlal 01-06-2004 -10-01-2010 R01/NIH/NIDDK Apical Cl-/OH-/HCO3- Exchanger in Kidney and GI Tract Role:Co-Investigator

Investigators:Amlal H 12-01-2002 -11-30-2003 Dialysis Centers Inc. - Paul Teschan Research Fund Coordinated downregulation of mTAL apical Na+-dependent transporters and collection duct water channel AQP2 in metabolic alkalosis Role:PI Completed

Investigators:Soleimani M, Amlal H 10-01-1998 -08-30-2003 NIH R01 (DK-54430) Cloning and charachterization of Na-dependent bicarbonate transporters Role:Co-Investigator Completed

Investigators:Amlal, Hassane 12-01-2002 -11-30-2004 Paul Teschan Research Fund Coordinated Downregulation of mTAL Aical Na+-Dependant Transporters and Collecting Duct Water Channel AQP2 in Metabolic Alkalosis Role:PI $39,354.00 Closed Level:Private Non-Profit

Grant: #R56 DK062809 Investigators:Amlal, Hassane; Lorenz, John; Soleimani, Manoocher 08-15-2009 -07-31-2010 National Inst of Diabetes and Digestive and Kidney Disease Apical Chloride/Bicarbonate Exchanges in Small Intestine and Kidney Role:Collaborator $460,826.00 Active Level:Federal

Grant: #R01 DK083582 Investigators:Amlal, Hassane; Conforti, Laura; Sheriff, Sulaiman 08-26-2010 -07-31-2015 National Inst of Diabetes and Digestive and Kidney Disease Regulation of Inorganic Phosphorus (Pi) Metabolism by Estrogen Role:PI $1,213,889.00 Active Level:Federal

Grant: #R01 HL127455 Investigators:Amlal, Hassane; McCormack, Francis 04-01-2015 -03-31-2019 National Heart, Lung and Blood Institute Pathogenesis-Driven Therapeutic Development for Pulmonary Alveolar Microlithiasis Role:Collaborator $409,364.00 Awarded Level:Federal

Grant: #Contract #20170100_Master Services Agreement Investigators:Amlal, Hassane; Srivastava, Ajay; Thakar, Charuhas 10-20-2016 -10-20-2021 Otsuka Pharmaceutical Development & Commercialization, Inc. Hyponatremia, Congestive Heart Failure, and Kidney Disease: A Vital Connection Role:Collaborator $.00 Active Level:Industry

Grant: #Task 1_2016 Otsuka Pharmaceutical_Thakar Investigators:Amlal, Hassane; Srivastava, Ajay; Thakar, Charuhas 01-31-2017 -12-31-2017 Otsuka Pharmaceutical Development & Commercialization, Inc. Hyponatremia, Congestive Heart Failure, and Kidney Disease: A Vital Connection Role:Collaborator $70,000.00 Active Level:Industry

Grant: #C-3965 Investigators:Amlal, Hassane 04-01-2017 -03-31-2018 Dialysis Clinic, Inc. Possible Role of Glutamine Transport and Metabolism in the Development of Diabetic Nephropathy Role:PI $25,000.00 Active Level:Private Non-Profit

Grant: #C-4095 Investigators:Amlal, Hassane 10-01-2018 -09-20-2020 Dialysis Clinic, Inc. Mechanism(s) of adenine-induced fluid loss in the kidney Role:PI $238,764.00 Awarded Level:Private Non-Profit

Grant: #CRFF-2018-004 Investigators:Amlal, Hassane; Dong, Fei; Kao, Winston Whei Yang 02-01-2019 -01-31-2020 Cystinosis Research Foundation Cell Therapy and Gene Editing for Cystinosis Role:Collaborator $179,834.00 Awarded Level:Private Non-Profit

Grant: #U01DA050330 Investigators:Amlal, Hassane; Crutchfield, Christopher; Dasenbrock-Gamm, Hanna; Kirley, Terence; Norman, Andrew; Rubinstein, Jack; Webster, Rose 09-15-2019 -07-31-2022 National Institute on Drug Abuse IND-Enabling Pre-Clinical Studies to Accelerate the Clinical Development of a Humanized Anti-Cocaine Monoclonal Antibody Role:Collaborator $1,796,316.00 Awarded Level:Federal

Publications

Published Abstracts

Bichara M, Amlal H, Mary F, Paillard M (1991. )NH4+/HCO3 - cotransport in medullar thick ascending limb (MTAL) .[Abstract]J Am Soc Nephrol, 2 ,696

Amlal H, Vernimmen C, Legoff C, Paillard M, Bichara M (1993. )Control of Na+-K+ (NH4+)-2Cl cotransport by angiotensin II (AII)-active transduction pathways in medullary thick ascending limb cells .[Abstract]J Am Soc Nephrol, 4 ,862

Bichara M, Amlal H, Laghmani P, Borensztein P, Paillard M (1995. )Control of NHE-3 transport activity by PKA, PKC, and arachidonic acid in MTAL cells .[Abstract]J Am Soc Nephrol, 6 ,332

Amlal H, Soleimani M (1996. )Activation of H+-ATPase by hypotonicity: A novel regulatory mechanism for H+ transport inner medulla .[Abstract]J Am Soc Nephrol, 7 ,1250

Amlal H, Soleimani M (1996. )A unique ammonium carrying transporter in the kidney inner medulla .[Abstract]J Am Soc Nephrol, 7 ,1250

Amlal H, Soleimani M (1996. )Induction of H+-ATPase by lethal acid stress: A mechanism for survival and accelerated growth in cultured inner medullary collecting duct cells .[Abstract]J Am Soc Nephrol, 7 ,1250

Amlal H, Wang Z, Burnham C, Soleimani M (1997. )A cloned Na+:HCO3 can function in Na+:OH cotransport mode .[Abstract]J Am Soc Nephrol, 8 ,2A

Burnham C, Amlal H, Wang Z, Shull G, Soleimani M (1997. )Molecular cloning and functional expression of a human Na+:HCO3 cotransporter .[Abstract]J Am Soc Nephrol, 8 ,3A

Nakamura S, Amlal H, Soleimani M, Galla J (1997. )Mechanism of HCO3 reabsorption in the perfused mouse OMCD and IMCD .[Abstract]J Am Soc Nephrol, 8 ,8A

Amlal H, Wang Z, Soleimani M (1997. )Potassium depletion downregulates apical chloride-absorbing transporters in rat kidney .[Abstract]J Am Soc Nephrol, 8 ,28A

Amlal H, Soleimani M (1997. )Induction of colonic H+-K+-ATPase 9cHKA) and upregulation of NHE-3 in proximal colon: compensatory mechanisms for Na+ and HCO3-reabsorption in diarrhea .[Abstract]J Am Soc Nephrol, 8 ,2A

Amlal H, Burnham C, Wang Z, Soleimani M (1998. )Regulation of cloned human Na+-HCO3-cotransport (NBC-1) by protein kinase pathways .[Abstract]J Am Soc Nephrol, 9 ,2A

Amlal H, Kishore B, Krane C, Soleimani M (1998. )Coordinated downregulation of apical Na+-K+2Cl cotransporter and aquaporin2 (AQP-2) in potassium depletion (KD): A basis for nephrogenic diabetes insipidus (DI) .[Abstract]J Am Soc Nephrol, 9 ,15A

Amlal H, Burnham E, Soleimani M (1998. )Potassium depletion upregulates the expression of the basolateral Na+-HCO3-cotransporter (NBC-1) in rat renal nephron segments .[Abstract]J Am Soc Nephrol, 9 ,2A

Nakamura S, Amlal H, Galla J, Soleimani M (1998. )Colonic H+-K+-ATPase is induced and mediates increased HCO3-reabsorption in inner medullary collecting duct (IMCDt) in potassium depletion .[Abstract]J Am Soc Nephrol, 9 ,41A

Nakamura S, Amlal P, Schulteis P, Galls J, Soleimani M (1998. )Compensatory HCO3-reabsorption in the distal nephron of NHE-3 deficient mouse .[Abstract]J Am Soc Nephrol, 9 ,10A

Ali R, Amlal H, Burnham C, Soleimani M (1998. )The effect of glucocorticoids on the expression and activity of the basolateral Na+-HCO3 cotransport (NBC-1) in renal proximal tubule .[Abstract]J Am Soc Nephrol, 9 ,1A

Amlal H, Habo K, Soleimani M (1999. )Potassium deprivation induces the expression of the basolateral Na+:HCO3 cotransporter (NBC-1) in medullary thick ascending limb (mTAL) .[Abstract]J Am Soc Nephrol, 10 ,1A

Burnham C, Shumaker H, Amlal H, Soleimani M (1999. )Magnesium depletion increases the expression of colonic H+-K+ ATPase in rat kidney: A basis for metabolic alkalosis in hypomagnesaemia .[Abstract]J Am Soc Nephrol, 10 ,2A

Nakamura S, Spicer Z, Amlal H, Shull G, Galla J, Soleimani M (1999. )Renal NH4+ secretion in colonic H+K+-ATPase (HKAc) deficient mouse: effect of K+ deprivation .[Abstract]J Am Soc Nephrol, 10 ,7A

Amlal H, Habo K, Wang Z, Soleimani M (1999. )Downregulation of Aquaporin 2 (AQP-2) in fasting rats: a basis for nephrogenic diabetes insipidus (DI) in starvation .[Abstract]J Am Soc Nephrol, 10 ,12A

Amlal H, Habo K, Soleimani M (1999. )Coordinated downregulation of apical Na+-K+-2Cl-(BSC-1) and Aquaporin (AQP-2) in chloride depletion alkalosis (CDA): a basis for alkalosis-induced polyuria .[Abstract]J Am Soc Nephrol, 10 ,12A

Amlal H, Chen Q, Soleimani M (2000. )Coordinated regulation of basolateral Na+: HCO3-cotransporter NBC-1 and apical Na+/H+ exchanger NHE-3 in bicarbonate loading .[Abstract]J Am Soc Nephrol, 11 ,1A

Greeley T, Wang Z, Amlal H, Soleimani M (2000. )Increased expression of rat renal colonic H-K-ATPase (HKAc) in fasting and bicarbonate loading .[Abstract]J Am Soc Nephrol, 2000 (11 ),-4A

Amlal H, Chen Q, Soleimani M (2000. )Effect of adrenalectomy and saline on fasting-induced urinary concentrating defect in rat .[Abstract]J Am Soc Nephrol, 11 ,13A

Amlal H, Chen Q, Soleimani M, (2000. )Metabolic acidosis upregulates the expression of Aquaporin-2 (AQP-2) water channel in rat kidney .[Abstract]J Am Soc Nephrol, 11 ,13A

Amlal H, Ledoussal C, Shull G, Soleimani M (2000. )Urinary concentrating defect in NHE-3 null mice .[Abstract]J Am Soc Nephrol, 11 ,12A

Quian C, Soleimani M, Amlal H (2001. )Thyroparathyroidectomy (TPTX) prevents the downregulation of proximal tubule (PT) apical Na+/H+ exchanger (NHE-3) and the basolateral Na+:HCO3- contransporter (NBC-1) by NaCl loading .[Abstract]J Am Soc Nephrol, 12 ,1A

Quian C, Soleimani M, Amlal H (2011. )Impaired urinary concentrating ability in aged Sprague Dawley rats .[Abstract]J Am Soc Nephrol, 12 ,14A

Quian C, Soleimani M, Amlal H (2001. )Dual effect of long-term fasting on urinary concentrating ability in rat kidney .[Abstract]J Am Soc Nephrol, 12 ,14A

Quian C, Soleimani M, Amlal H (2001. )Possible role of corticosterone in short-term (24hrs) fasting-induced polyuria and downregulation of AQP2 in rat kidney .[Abstract]J Am Soc Nephrol, 12 ,14A

Amlal H, Wilke C (2002. )Effects of fasting on adrenal steroid metabolism: role in Na+ retention by the kidney .[Abstract]J Am Soc Nephrol, 13 ,76A

Amlal H, Wilke C (2002. )Effects of food deprivation on renal apical Na+-dependent transporters .[Abstract]J Am Soc Nephrol, 13 ,279A

Amlal H, Soleimani M, Wilke C (2003. )Acetazolamide blocks the acidosis-induced upregulation of ammoniagenesis and gluconeogenesis enzymes in mouse kidney .[Abstract]J Am Soc Nephrol, 14 ,305A

Amlal H, Sheriff S, Soleiman M, Wilke C (2003. )Downregulation of medullary thick ascending limb (mTAL) apical Na+-dependent transporters and collecting duct (CD) water channels in metabolic alkalosis .[Abstract]J Am Soc Nephrol, 14 ,310A

Amlal H, Faroqui S (2004. )Metabolic acidosis downregulates the apical calcium channel (ECaC 1) and basolateral Na+/Ca++ exchanger (NCX1) in rat kidney and causes hypercaliuria .[Abstract]J Am Soc Nephrol, 15 ,312A

Amlal H, Faroqui S (2004. )Metabolic acidosis has dual effect on sodium handling by rat kidney .[Abstract]J Am Soc Nephrol, 15 ,312A

Amlal H, Faroqui S, Barone S, Petrovic S, Soleimani M (2004. )Effect of chronic vasopressin treatment on acid-base balance and acid-base transporters in the collecting duct .[Abstract]J Am Soc Nephrol, 15 ,72A

Petrovic A, Amlal H, Ma L, Miskin A, Barone S, Soleimani M (2004. )Effects of vasopressin and aldosterone on Slc26A7 in rat kidney .[Abstract]J Am Soc Nephrol, 77A

Amlal H, Faroqui S (2005. )Escape from hypercalcemia-induced polyuria and urinary concentrating defect in ovariectomized rats .[Abstract]J Am Soc Nephrol, 16 ,130A

Amlal H, Chaudry F, Faroqui S (2005. )Coordinated upregulation of Na+-glutamine cotransporter (SN1) and ammoniagenesis enzymes in the kidney cortex of potassium-deprived rats .[Abstract]J Am Soc Nephrol, 16 ,125A

Faroqui S, Sheriff S, Soleimani M, Amlal H (2005. )High protein diet upregulates the Na+-K+-2Cl cotransporter (NKCC2 or BSC1) in the medullary thick ascending limb of rat kidney .[Abstract]J Am Soc Nephrol, 16 ,348A

Amlal H, Wang Z, Barone S, Soleimani M (2005. )Compensatory upregulation of ion transporters in the kidney proximal tubule of Slc26a6 null mice .[Abstract]J Am Soc Nephrol, 16 ,351A

Amlal H, Barone S, Soleimani M (2006. )Regulation of pendrin in water deprivation and sodium depletion .[Abstract]J Am Soc Nephrol, 17 ,473A

Amlal H, Faroqui S, Khakwani H (2006. )Molecular mechanisms of increased ammoniagenesis in the kidney proximal tubule of potassium-deprived rats .[Abstract]J Am Soc Nephrol, 17 ,533A

Barone S, Amlal H, Wang Z, Soleimani M (2006. )Differential regulation of the CI-/base exchanger SLC26A6 and the Na+/H+ exchanger NHE3 in the proximal tubule and the CI/base exchangers AE1 and SLC26A7 in the OMCD in potassium depletion .[Abstract]J Am Soc Nephrol, 17 ,579A

Amlal H, Khakwani H (2006. )Distribution of glutamine transporters in the kidney and upregulation of ASCT2 in metabolic acidosis .[Abstract]J Am Soc Nephrol, 17 ,817A

Amlal H, Levi M, Faroqui S (2007. )Estrogen downregulates the expression of proximal tubule Na-Pi cotransporter (NaPi-lia) and causes phosphaturia in ovariectomized rats .[Abstract]J Am Soc Nephrol, 18 ,56A

Amlal H (2007. )Acid loading downregulates the expression of Claudin-2 and Claudin-10 in the proximal tubule of rat kidney .[Abstract]J Am Soc Nephrol, 18 ,116A

Singh A, Amlal H, Haas P, Dringenberg U, Fussell S, Barone S, Engelhardt R, Zuo J, Seidler U, Soleimani M (2007. )The chloride/base exchanger Slc26a6 (PAT1) plays an essential role in the pathogenesis of fructose-induced hypertension .[Abstract]J Am Soc Nephrol, 18 ,598A

Shaikh A, Soleimani M, Amlal H (2008. )Estrogen upregulates the Na+-glutamine contransporter (SN1) but does not stimulate ammoniagenesis in ovariectomized rat kidney .[Abstract]J Am Soc Nephrol, 18 ,347A

Amlal H, Barone S, Xu Jie, Soleimani M (2008. )Ablation of the chloride/base exchanger Slc26a6 (PAT1: CFEX) blocks fructose-induced hypertension in part by increasing salt excretion in the kidny .[Abstract]J Am Soc Nephrol, 18 ,347A

Bishop J, Werlander J, Lee H, Wronski J, Amlal H, Handlogten M, Dweiner I (2008. )Role of estrogen in basal renal ammonia metabolism .[Abstract]J Am Soc Nephrol, 18 ,347A

Amlal H, Barone S, Sharif S, Zuo J, Soleimani M (2008. )Deletion of the fructose-facilitated transporter Glut5 confers insulin resistance .[Abstract]J Am Soc Nephrol, 18 ,647A

Barone S, Fussell S, Singh A, Amlal H, Xu J, Seidler U, Zuo J, Soleimani M (2008. )The Slc2a5 (Glut5) is absolutely essential for the absorption of fructose in intestine and generation of fructose-induced hypertension .[Abstract]J Am Soc Nephrol, 18 ,381A

Amlal H, Xu J, Petrovic S, Barone S, Miller M, Soleimani M (2009. )Deletion of Slc26a4 (pendrin) impairs bicarbonate secretion in the collecting duct but does not affect the apical Cl-/HCO3-exchanger activity in B-intercalated cells .[Abstract]J Am Soc Nephrol, 20 ,33A

Xu J, Song P, Nakamura S, Miller M, Barone S, Alper S, Riederer B, Bonhagen J, Arend L, Amlal H, Siedler U, Soleimani M (2009. )Deletion of the chloride/base exchanger Slc26a7 causes distal renal tubular acidosis and impairs gastric acid secretion .[Abstract]J Am Soc Nephrol, 20 ,33A

Amlal H (2009. )Estrogen downregulates the expression of 24-hydroxylase (CYP24A1) in the kidney cortex of ovariectomized rats .[Abstract]J Am Soc Nephrol, 20 ,539A

Amlal H, Barone S, Xu J, Zahedi K, Soleimani M (2010. )The anion transporter Slc26a9 plays an important role in systemic blood pressure control by regulating renal chloride excretion .[Abstract]J Am Soc Nephrol, 21 ,109A

Amlal H, Barone S, Xi J, Soleimani M (2010. )Pendrin conferes partial resistance to the diuretic effect of loop and thiazide diuretics in mice .[Abstract]J Am Soc Nephrol, 21 ,480A

Amlal H (2010. )Role of glutamine transport and metabolism in the development of renal hypertrophy .[Abstract]J Am Soc Nephrol, 21 ,480A

Li H, Zhaopeng D, Barone S, Amlal H, McDonough A, Wang T, Soleimani M (2011. )Generation and examination of proximal tubule specific Na+/H+ exchanger NHE3 knockout mouse .[Abstract]J Am Soc Nephrol, 22 ,79A

Soleimani M, Amlal H, Barone S, Xu J, Siddiqui F (2011. )Double-knockout of pendrin and NaCl cotransporter causes salt wasting, profound dehydration and nephrogenic diabetes insipidus .[Abstract]J Am Soc Nephrol, 22 ,80A

Siddiqui F, Soleimani M, Amlal H (2011. )Deletion of glutamine/neutral amino acid transporter ASCT2 (ATB0) does not alter acid-base regulation under baseline condition or in response to acid loading .[Abstract]J Am Soc Nephrol, 22 ,264A

Barone S, Xu J, Amlal H, Soleimani M (2011. )Deletion of the Cl-/HCO3-exchanger pendrin downregulates calcium-absorbing proteins in the kidney and causes calcium wasting .[Abstract]J Am Soc Nephrol, 22 ,268A

Siddiqui F, Levi M, Amlal H (2011. )Estrogen causes phosphaturia through specific downregulation of NaPi-IIa via the activation of both estrogen receptors ERx and ERb .[Abstract]J Am Soc Nephrol, 22 ,743A

Peer Reviewed Publications

Petrovic,S.; Barone,S.; Wang,Z.; McDonough,A.A.; Amlal,H.; Soleimani,M. (2008. )Slc26a6 (pat1) deletion downregulates the apical Na+/H + exchanger in the straight segment of the proximal tubule .American Journal of Nephrology, ,28 (2 ),330 -338

Barone,S.; Amlal,H.; Kujala,M.; Xu,J.; Karet,F.; Blanchard,A.; Kere,J.; Soleimani,M. (2007. )Regulation of the basolateral chloride/base exchangers ae1 and slc26a7 in the kidney collecting duct in potassium depletion .Nephrology Dialysis Transplantation, ,22 (12 ),3462 -3470

Wagner,E.A.; Falciglia,G.A.; Amlal,H.; Levin,L.; Soleimani,M. (2007. )Short-term exposure to a high-protein diet differentially affects glomerular filtration rate but not acid-base balance in older compared to younger adults .Journal of the American Dietetic Association, ,107 (8 ),1404 -1408

Faroqui,S.; Sheriff,S.; Amlal,H. (2006. )Metabolic acidosis has dual effects on sodium handling by rat kidney .American Journal of Physiology - Renal Physiology, ,291 (2 ),F322 -F331

Amlal,H.; Sheriff,S.; Faroqui,S.; Ma,L.; Barone,S.; Petrovic,S.; Soleimani,M. (2006. )Regulation of acid-base transporters by vasopressin in the kidney collecting duct of brattleboro rat .American Journal of Nephrology, ,26 (2 ),194 -205

Petrovic,S.; Amlal,H.; Sun,X.; Karet,F.; Barone,S.; Soleimani,M. (2006. )Vasopressin induces expression of the cl-/hco3 - exchanger slc26a7 in kidney medullary collecting ducts of brattleboro rats .American Journal of Physiology - Renal Physiology, ,290 (5 ),F1194 -F1201

Xu,J.; Worrell,R.T.; Li,H.C.; Barone,S.L.; Petrovic,S.; Amlal,H.; Soleimani,M. (2006. )Chloride/bicarbonate exchanger slc26a7 is localized in endosomes in medullary collecting duct cells and is targeted to the basolateral membrane in hypertonicity and potassium depletion .Journal of the American Society of Nephrology, ,17 (4 ),956 -967

Amlal,H.; Faroqui,S.; Balasubramaniam,A.; Sheriff,S. (2006. )Estrogen up-regulates neuropeptide y y1 receptor expression in a human breast cancer cell line .Cancer Research, ,66 (7 ),3706 -3714

Wilke,C.; Sheriff,S.; Soleimani,M.; Amlal,H. (2005. )Vasopressin-independent regulation of collecting duct aquaporin-2 in food deprivation .Kidney International, ,67 (1 ),201 -216

Nonoguchi,H.; Inoue,T.; Mori,T.; Nakayama,Y.; Kohda,Y.; Tomita,K.; Amlal,H.; Sheriff,S.; Soleimani,M. (2004. )Regulation of aquaporin-2 by metabolic acidosis (multiple letters) .American Journal of Physiology - Cell Physiology, ,287 (3 56-3 ),C814 -C815

Barone,S.; Amlal,H.; Xu,J.; Kujala,M.; Kere,J.; Petrovic,S.; Soleimani,M. (2004. )Differential regulation of basolateral cl-/hco3 - exchangers slc26a7 and ae1 in kidney outer medullary collecting duct .Journal of the American Society of Nephrology, ,15 (8 ),2002 -2011

Amlal,H.; Sheriff,S.; Soleimani,M. (2004. )Upregulation of collecting duct aquaporin-2 by metabolic acidosis: role of vasopressin .American Journal of Physiology - Cell Physiology, ,286 (5 55-5 ),C1019 -C1030

Amlal,H.; Ledoussal,C.; Sheriff,S.; Shull,G.E.; Soleimani,M. (2003. )Downregulation of renal aqp2 water channel and nkcc2 in mice lacking the apical na+-h+ exchanger nhe3 .Journal of Physiology, ,553 (2 ),511 -522

Amlal,H.; Wilke,C. (2003. )Resistance of mtal na+-dependent transporters and collecting duct aquaporins to dehydration in 7-month-old rats .Kidney International, ,64 (2 ),544 -554

Xu,J.; Wang,Z.; Barone,S.; Petrovic,M.; Amlal,H.; Conforti,L.; Petrovic,S.; Soleimani,M. (2003. )Expression of the na+-hco3 - cotransporter nbc4 in rat kidney and characterization of a novel nbc4 variant .American Journal of Physiology - Renal Physiology, ,284 (1 53-1 ),F41 -F50

Amlal,H.; Chen,Q.; Greeley,T.; Pavelic,L.; Soleimani,M. (2001. )Coordinated down-regulation of nbc-1 and nhe-3 in sodium and bicarbonate loading .Kidney International, ,60 (5 ),1824 -1836

Amlal,H.; Habo,K.; Soleimani,M. (2001. )Erratum: potassium deprivation upregulates expression of renal basolateral na+-hco3 cotransporter (nbc-1) (american journal of physiology (september 2000) 279 (f532-f543)) .American Journal of Physiology - Renal Physiology, ,280 (6 49-6 ),

Amlal,H.; Chen,Q.; Habo,K.; Wang,Z.; Soleimani,M. (2001. )Fasting downregulates renal water channel aqp2 and causes polyuria .American Journal of Physiology - Renal Physiology, ,280 (3 49-3 ),F513 -F523

Wang,Z.; Conforti,L.; Petrovic,S.; Amlal,H.; Burnham,C.E.; Soleimani,M. (2001. )Mouse na+:hco3 - cotransporter isoform nbc-3 (knbc-3): cloning, expression, and renal distribution .Kidney International, ,59 (4 ),1405 -1414

Soleimani,M.; Greeley,T.; Petrovic,S.; Wang,Z.; Amlal,H.; Kopp,P.; Burnham,C.E. (2001. )Pendrin: an apical cl-/oh-/hco3 - exchanger in the kidney cortex .American Journal of Physiology - Renal Physiology, ,280 (2 49-2 ),F356 -F364

Attmane-Elakeb,A.; Amlal,H.; Bichara,M. (2001. )Ammonium carriers in medullary thick ascending limb .American Journal of Physiology - Renal Physiology, ,280 (1 49-1 ),F1 -F9

Amlal,H.; Krane,C.M.; Chen,Q.; Soleimani,M. (2000. )Early polyuria and urinary concentrating defect in potassium deprivation .American Journal of Physiology - Renal Physiology, ,279 (4 48-4 ),F655 -F663

Nakamura,S.; Amlal,H.; Soleimani,M.; Galla,J.H. (2000. )Pathways for hco3 - reabsorption in mouse medullary collecting duct segments .Journal of Laboratory and Clinical Medicine, ,136 (3 ),218 -223

Amlal,H.; Habo,K.; Soleimani,M. (2000. )Potassium deprivation upregulates expression of renal basolateral na+-hco3/- cotransporter (nbc-1) .American Journal of Physiology - Renal Physiology, ,279 (3 48-3 ),F532 -F543

Ali,R.; Amlal,H.; Burnham,C.E.; Soleimani,M. (2000. )Glucocorticoids enhance the expression of the basolateral na+:hco3 - cotransporter in renal proximal tubules .Kidney International, ,57 (3 ),1063 -1071

Nakamura,S.; Amlal,H.; Galla,J.H.; Soleimani,M. (1999. )Nh4 + secretion in inner medullary collecting duct in potassium deprivation: role of colonic h+-k+-atpase .Kidney International, ,56 (6 ),2160 -2167

Amlal,H.; Burnham,C.E.; Soleimani,M. (1999. )Erratum: characterization of na+/hco3/- cotransporter isoform nbc-3 (american journal of physiology-advances in physiology education (june 1999) 276:46 (f903-f913)) .American Journal of Physiology - Advances in Physiology Education, ,22 (1 ),

Amlal,H.; Burnham,C.E.; Soleimani,M. (1999. )Characterization of na+/hco3/- cotransporter isoform nbc-3 .American Journal of Physiology - Renal Physiology, ,276 (6 45-6 ),F903 -F913

Nakamura,S.; Amlal,H.; Schultheis,P.J.; Galla,J.H.; Shull,G.E.; Soleimani,M. (1999. )Hco3/- reabsorption in renal collecting duct of nhe-3-deficient mouse: a compensatory response .American Journal of Physiology - Renal Physiology, ,276 (6 45-6 ),F914 -F921

Shumaker,H.; Amlal,H.; Frizzell,R.; Ulrich II,C.D.; Soleimani,M. (1999. )Cftr drives na+-nhcp3/- cotransport in pancreatic duct cells: a basis for defective hco3/- secretion in cf .American Journal of Physiology - Cell Physiology, ,276 (1 45-1 ),C16 -C25

Amlal,H.; Burnham,C.E.; Soleimani,M. (1999. )Erratum: characterization of na+/hco3/- cotransporter isoform nbc-3 (american journal of physiology - renal physiology (june 1999) 276 (f903- f913)) .American Journal of Physiology - Renal Physiology, ,277 (3 46-3 ),

Nakamura,S.; Amlal,H.; Galla,J.H.; Soleimani,M. (1998. )Colonic h+-k+-atpase is induced and mediates increased hco3- reabsorption in inner medullary collecting duct in potassium depletion .Kidney International, ,54 (4 ),1233 -1239

Amlal,H.; Goel,A.; Soleimani,M. (1998. )Activation of h+-atpase by hypotonicity: a novel regulatory mechanism for h+ secretion in imcd cells .American Journal of Physiology - Renal Physiology, ,275 (4 44-4 ),F487 -F501

Amlal,H.; Wang,Z.; Burnham,C.; Soleimani,M. (1998. )Functional characterization of a cloned human kidney na+:hco3/- cotransporter .Journal of Biological Chemistry, ,273 (27 ),16810 -16815

Burnham,C.E.; Flagella,M.; Wang,Z.; Amlal,H.; Shull,G.E.; Soleimani,M. (1998. )Cloning, renal distribution, and regulation of the rat na+-hco3/- cotransporter .American Journal of Physiology - Renal Physiology, ,274 (6 43-6 ),F1119 -F1126

Amlal,H.; LeGoff,C.; Vernimmen,C.; Soleimani,M.; Paillard,M.; Bichara,M. (1998. )Ang ii controls na+-k+(NH4/+)-2cl- cotransport via 20-hete and pkc in medullary thick ascending limb .American Journal of Physiology - Cell Physiology, ,274 (4 43-4 ),C1047 -C1056

Amlal,H.; Wang,Z.; Soleimani,M. (1998. )Potassium depletion downregulates chloride-absorbing transporters in rat kidney .Journal of Clinical Investigation, ,101 (5 ),1045 -1054

Amlal,H.; Wang,Z.; Soleimani,M. (1997. )Functional upregulation of h+-atpase by lethal acid stress in cultured inner medullary collecting duct cells .American Journal of Physiology - Cell Physiology, ,273 (4 42-4 ),C1194 -C1205

Burnham,C.E.; Amlal,H.; Wang,Z.; Shull,G.E.; Soleimani,M. (1997. )Cloning and functional expression of a human kidney na+:hoc3 - cotransporter .Journal of Biological Chemistry, ,272 (31 ),19111 -19114

Amlal,H.; Soleimani,M. (1997. )K+/nh4 + antiporter: a unique ammonium carrying transporter in the kidney inner medulla .Biochimica et Biophysica Acta - Biomembranes, ,1323 (2 ),319 -333

Amlal,H.; Soleimani,M. (1996. )Induction of h+-atpase by lethal acid stress: a mechanism for survival and accelerated growth in cultured inner medullary collecting duct cells .Journal of the American Society of Nephrology, ,7 (9 ),1250

Amlal,H.; Soleimani,M. (1996. )Activation of h+-atpase by hypotonicity: a novel regulatory mechanism for h+ transport in inner medulla .Journal of the American Society of Nephrology, ,7 (9 ),1250

Amlal,H.; Soleimani,M. (1996. )K+/nh4+ antiporter: a unique ammonium carrying transporter in the kidney inner medulla .Journal of the American Society of Nephrology, ,7 (9 ),1250

Amlal,H.; Legoff,C.; Vernimmen,C.; Paillard,M.; Bichara,M. (1996. )Na+-k+(nh4/+)-2cl- cotransport in medullary thick ascending limb: control by pka, pkc, and 20-hete .American Journal of Physiology - Cell Physiology, ,271 (2 40-2 ),C455 -C463

Amlal,H.; Paillard,M.; Bichara,M. (1994. )Cl--dependent nh4/+ transport mechanisms in medullary thick ascending limb cells .American Journal of Physiology - Cell Physiology, ,267 (6 36-6 ),C1607 -C1615

Amlal,H.; Paillard,M.; Bichara,M. (1994. )Nh4/+ transport pathways in cells of medullary thick ascending limb of rat kidney. nh4/+ conductance and k+/nh4/+(h+) antiport .Journal of Biological Chemistry, ,269 (35 ),21962 -21971

Barone, Sharon; Amlal, Hassane; Xu, Jie; Soleimani, Manoocher (2012. )Deletion of the Cl-/HCO3- exchanger pendrin downregulates calcium-absorbing proteins in the kidney and causes calcium wasting.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, ,27 (4 ),1368-79

Abu Hossain, Shaikh; Chaudhry, Farrukh A; Zahedi, Kamyar; Siddiqui, Faraaz; Amlal, Hassane (2011. )Cellular and molecular basis of increased ammoniagenesis in potassium deprivation.American journal of physiology. Renal physiology, ,301 (5 ),F969-78

Amlal, Hassane; Soleimani, Manoocher (2011. )Pendrin as a novel target for diuretic therapy.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, ,28 (3 ),521-6

Zahedi, Kamyar; Barone, Sharon; Kramer, Debora L; Amlal, Hassane; Alhonen, Leena; Jänne, Juhani; Porter, Carl W; Soleimani, Manoocher (2010. )The role of spermidine/spermine N1-acetyltransferase in endotoxin-induced acute kidney injury.American journal of physiology. Cell physiology, ,299 (1 ),C164-74

Amlal, Hassane; Petrovic, Snezana; Xu, Jie; Wang, Zhaohui; Sun, Xuming; Barone, Sharon; Soleimani, Manoocher (2010. )Deletion of the anion exchanger Slc26a4 (pendrin) decreases apical Cl(-)/HCO3(-) exchanger activity and impairs bicarbonate secretion in kidney collecting duct.American journal of physiology. Cell physiology, ,299 (1 ),C33-41

Sheriff, Sulaiman; Ali, Marwan; Yahya, Ayesha; Haider, Khawaja H; Balasubramaniam, Ambikaipakan; Amlal, Hassane (2010. )Neuropeptide Y Y5 receptor promotes cell growth through extracellular signal-regulated kinase signaling and cyclic AMP inhibition in a human breast cancer cell line.Molecular cancer research : MCR, ,8 (4 ),604-14

Xu, Jie; Song, Penghong; Nakamura, Suguru; Miller, Marian; Barone, Sharon; Alper, Seth L; Riederer, Brigitte; Bonhagen, Janina; Arend, Lois J; Amlal, Hassane; Seidler, Ursula; Soleimani, Manoocher (2009. )Deletion of the chloride transporter slc26a7 causes distal renal tubular acidosis and impairs gastric acid secretion.The Journal of biological chemistry, ,284 (43 ),29470-9

Balkovetz, Daniel F; Chumley, Phillip; Amlal, Hassane (2009. )Downregulation of claudin-2 expression in renal epithelial cells by metabolic acidosis.American journal of physiology. Renal physiology, ,297 (3 ),F604-11

Barone, Sharon; Fussell, Stacey L; Singh, Anurag Kumar; Lucas, Fred; Xu, Jie; Kim, Charles; Wu, Xudong; Yu, Yiling; Amlal, Hassane; Seidler, Ursula; Zuo, Jian; Soleimani, Manoocher (2009. )Slc2a5 (Glut5) is essential for the absorption of fructose in the intestine and generation of fructose-induced hypertension.The Journal of biological chemistry, ,284 (8 ),5056-66

Singh, Anurag Kumar; Amlal, Hassane; Haas, Patrick J; Dringenberg, Ulrike; Fussell, Stacey; Barone, Sharon L; Engelhardt, Regina; Zuo, Jian; Seidler, Ursula; Soleimani, Manoocher (2008. )Fructose-induced hypertension: essential role of chloride and fructose absorbing transporters PAT1 and Glut5.Kidney international, ,74 (4 ),438-47

Petrovic, Snezana; Barone, Sharon; Wang, Zhaohui; McDonough, Alicia A; Amlal, Hassane; Soleimani, Manoocher (2008. )Slc26a6 (PAT1) deletion downregulates the apical Na+/H+ exchanger in the straight segment of the proximal tubule.American journal of nephrology, ,28 (2 ),330-8

Barone, Sharon; Amlal, Hassane; Kujala, Minna; Xu, Jie; Karet, Fiona; Blanchard, Ann; Kere, Juha; Soleimani, Manoocher (2007. )Regulation of the basolateral chloride/base exchangers AE1 and SLC26A7 in the kidney collecting duct in potassium depletion.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, ,22 (12 ),3462-70

Wagner, Erin A; Falciglia, Grace A; Amlal, Hassane; Levin, Linda; Soleimani, Manoocher (2007. )Short-term exposure to a high-protein diet differentially affects glomerular filtration rate but not Acid-base balance in older compared to younger adults.Journal of the American Dietetic Association, ,107 (8 ),1404-8

Faroqui, Somia; Sheriff, Sulaiman; Amlal, Hassane (2006. )Metabolic acidosis has dual effects on sodium handling by rat kidney.American journal of physiology. Renal physiology, ,291 (2 ),F322-31

Petrovic, Snezana; Amlal, Hassane; Sun, Xuming; Karet, Fiona; Barone, Sharon; Soleimani, Manoocher (2006. )Vasopressin induces expression of the Cl-/HCO3- exchanger SLC26A7 in kidney medullary collecting ducts of Brattleboro rats.American journal of physiology. Renal physiology, ,290 (5 ),F1194-201

Amlal, Hassane; Faroqui, Somia; Balasubramaniam, Ambikaipakan; Sheriff, Sulaiman (2006. )Estrogen up-regulates neuropeptide Y Y1 receptor expression in a human breast cancer cell line.Cancer research, ,66 (7 ),3706-14

Xu, Jie; Worrell, Roger T; Li, Hong C; Barone, Sharon L; Petrovic, Snezana; Amlal, Hassane; Soleimani, Manoocher (2006. )Chloride/bicarbonate exchanger SLC26A7 is localized in endosomes in medullary collecting duct cells and is targeted to the basolateral membrane in hypertonicity and potassium depletion.Journal of the American Society of Nephrology : JASN, ,17 (4 ),956-67

Amlal, Hassane; Sheriff, Sulaiman; Faroqui, Somia; Ma, Liyun; Barone, Sharone; Petrovic, Snezana; Soleimani, Manoocher (2006. )Regulation of acid-base transporters by vasopressin in the kidney collecting duct of Brattleboro rat.American journal of nephrology, ,26 (2 ),194-205

Wilke, Catherine; Sheriff, Sulaiman; Soleimani, Manoocher; Amlal, Hassane (2005. )Vasopressin-independent regulation of collecting duct aquaporin-2 in food deprivation.Kidney international, ,67 (1 ),201-16

Barone, Sharon; Amlal, Hassane; Xu, Jie; Kujala, Minna; Kere, Juha; Petrovic, Snezana; Soleimani, Manoocher (2004. )Differential regulation of basolateral Cl-/HCO3- exchangers SLC26A7 and AE1 in kidney outer medullary collecting duct.Journal of the American Society of Nephrology : JASN, ,15 (8 ),2002-11

Amlal, Hassane; Sheriff, Sulaiman; Soleimani, Manoocher (2004. )Upregulation of collecting duct aquaporin-2 by metabolic acidosis: role of vasopressin.American journal of physiology. Cell physiology, ,286 (5 ),C1019-30

Amlal, Hassane; Ledoussal, Clara; Sheriff, Sulaiman; Shull, Gary E; Soleimani, Manoocher (2003. )Downregulation of renal AQP2 water channel and NKCC2 in mice lacking the apical Na+-H+ exchanger NHE3.The Journal of physiology, ,553 (Pt 2 ),511-22

Amlal, Hassane; Wilke, Catherine (2003. )Resistance of mTAL Na+-dependent transporters and collecting duct aquaporins to dehydration in 7-month-old rats.Kidney international, ,64 (2 ),544-54

Xu, Jie; Wang, Zhaohui; Barone, Sharone; Petrovic, Milan; Amlal, Hassane; Conforti, Laura; Petrovic, Snezana; Soleimani, Manoocher (2003. )Expression of the Na+-HCO-3 cotransporter NBC4 in rat kidney and characterization of a novel NBC4 variant.American journal of physiology. Renal physiology, ,284 (1 ),F41-50

Webster, Rose; Sheriff, Sulaiman; Faroqui, Rashma; Siddiqui, Faraaz; Hawse, John R; Amlal, Hassane (2016. )Klotho/fibroblast growth factor 23- and PTH-independent estrogen receptor-?-mediated direct downregulation of NaPi-IIa by estrogen in the mouse kidney.American journal of physiology. Renal physiology, ,311 (2 ),F249-59

Saito, Atsushi; Nikolaidis, Nikolaos M; Amlal, Hassane; Uehara, Yasuaki; Gardner, Jason C; LaSance, Kathleen; Pitstick, Lori B; Bridges, James P; Wikenheiser-Brokamp, Kathryn A; McGraw, Dennis W; Woods, Jason C; Sabbagh, Yves; Schiavi, Susan C; Altini?ik, Göksel; Jakopovi?, Marko; Inoue, Yoshikazu; McCormack, Francis X (2015. )Modeling pulmonary alveolar microlithiasis by epithelial deletion of the Npt2b sodium phosphate cotransporter reveals putative biomarkers and strategies for treatment.Science translational medicine, ,7 (313 ),313ra181

Burris, Dara; Webster, Rose; Sheriff, Sulaiman; Faroqui, Rashma; Levi, Moshe; Hawse, John R; Amlal, Hassane (2015. )Estrogen directly and specifically downregulates NaPi-IIa through the activation of both estrogen receptor isoforms (ER? and ER?) in rat kidney proximal tubule.American journal of physiology. Renal physiology, ,308 (6 ),F522-34

Hsieh, H; Amlal, H; Genter, M B (2015. )Evaluation of the toxicity of zinc in the rat olfactory neuronal cell line, Odora.Human & experimental toxicology, ,34 (3 ),308-14

Amlal, Hassane; Xu, Jie; Barone, Sharon; Zahedi, Kamyar; Soleimani, Manoocher (2013. )The chloride channel/transporter Slc26a9 regulates the systemic arterial pressure and renal chloride excretion.Journal of molecular medicine (Berlin, Germany), ,91 (5 ),561-72

Zahedi, Kamyar; Barone, Sharon L; Xu, Jie; Steinbergs, Nora; Schuster, Rebecca; Lentsch, Alex B; Amlal, Hassane; Wang, Jiang; Casero, Robert A; Soleimani, Manoocher (2012. )Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCl4-induced acute liver injury.American journal of physiology. Gastrointestinal and liver physiology, ,303 (5 ),G546-60

Soleimani, Manoocher; Barone, Sharon; Xu, Jie; Shull, Gary E; Siddiqui, Faraz; Zahedi, Kamyar; Amlal, Hassane (2012. )Double knockout of pendrin and Na-Cl cotransporter (NCC) causes severe salt wasting, volume depletion, and renal failure.Proceedings of the National Academy of Sciences of the United States of America, ,109 (33 ),13368-73

Faroqui, S; Levi, M; Soleimani, M; Amlal, H (2008. )Estrogen downregulates the proximal tubule type IIa sodium phosphate cotransporter causing phosphate wasting and hypophosphatemia.Kidney international, ,73 (10 ),1141-50

Amlal, H; Chen, Q; Greeley, T; Pavelic, L; Soleimani, M (2001. )Coordinated down-regulation of NBC-1 and NHE-3 in sodium and bicarbonate loading.Kidney international, ,60 (5 ),1824-36

Wang, Z; Conforti, L; Petrovic, S; Amlal, H; Burnham, C E; Soleimani, M (2001. )Mouse Na+: HCO3- cotransporter isoform NBC-3 (kNBC-3): cloning, expression, and renal distribution.Kidney international, ,59 (4 ),1405-14

Amlal, H; Chen, Q; Habo, K; Wang, Z; Soleimani, M (2001. )Fasting downregulates renal water channel AQP2 and causes polyuria. American journal of physiology. Renal physiology, ,280 (3 ),F513-23

Soleimani, M; Greeley, T; Petrovic, S; Wang, Z; Amlal, H; Kopp, P; Burnham, C E (2001. )Pendrin: an apical Cl-/OH-/HCO3- exchanger in the kidney cortex. American journal of physiology. Renal physiology, ,280 (2 ),F356-64

Amlal, H; Krane, C M; Chen, Q; Soleimani, M (2000. )Early polyuria and urinary concentrating defect in potassium deprivation. American journal of physiology. Renal physiology, ,279 (4 ),F655-63

Amlal, H; Habo, K; Soleimani, M (2000. )Potassium deprivation upregulates expression of renal basolateral Na(+)-HCO(3)(-) cotransporter (NBC-1). American journal of physiology. Renal physiology, ,279 (3 ),F532-43

Nakamura, S; Amlal, H; Soleimani, M; Galla, J H (2000. )Pathways for HCO3-reabsorption in mouse medullary collecting duct segments.The Journal of laboratory and clinical medicine, ,136 (3 ),218-23

Ali, R; Amlal, H; Burnham, C E; Soleimani, M (2000. )Glucocorticoids enhance the expression of the basolateral Na+:HCO3- cotransporter in renal proximal tubules.Kidney international, ,57 (3 ),1063-71

Nakamura, S; Amlal, H; Schultheis, P J; Galla, J H; Shull, G E; Soleimani, M (1999. )HCO-3 reabsorption in renal collecting duct of NHE-3-deficient mouse: a compensatory response. The American journal of physiology, ,276 (6 Pt 2 ),F914-21

Amlal, H; Burnham, C E; Soleimani, M (1999. )Characterization of Na+/HCO-3 cotransporter isoform NBC-3. The American journal of physiology, ,276 (6 Pt 2 ),F903-13

Shumaker, H; Amlal, H; Frizzell, R; Ulrich, C D; Soleimani, M (1999. )CFTR drives Na+-nHCO-3 cotransport in pancreatic duct cells: a basis for defective HCO-3 secretion in CF. The American journal of physiology, ,276 (1 Pt 1 ),C16-25

Amlal, H; Goel, A; Soleimani, M (1998. )Activation of H+-ATPase by hypotonicity: a novel regulatory mechanism for H+ secretion in IMCD cells. The American journal of physiology, ,275 (4 Pt 2 ),F487-501

Nakamura, S; Amlal, H; Galla, J H; Soleimani, M (1998. )Colonic H+-K+-ATPase is induced and mediates increased HCO3- reabsorption in inner medullary collecting duct in potassium depletion.Kidney international, ,54 (4 ),1233-9

Amlal, H; Wang, Z; Burnham, C; Soleimani, M (1998. )Functional characterization of a cloned human kidney Na+:HCO3- cotransporter. The Journal of biological chemistry, ,273 (27 ),16810-5

Burnham, C E; Flagella, M; Wang, Z; Amlal, H; Shull, G E; Soleimani, M (1998. )Cloning, renal distribution, and regulation of the rat Na+-HCO3- cotransporter. The American journal of physiology, ,274 (6 Pt 2 ),F1119-26

Amlal, H; Wang, Z; Soleimani, M (1998. )Potassium depletion downregulates chloride-absorbing transporters in rat kidney.The Journal of clinical investigation, ,101 (5 ),1045-54

Amlal, H; Wang, Z; Soleimani, M (1997. )Functional upregulation of H+-ATPase by lethal acid stress in cultured inner medullary collecting duct cells. The American journal of physiology, ,273 (4 Pt 1 ),C1194-205

Burnham, C E; Amlal, H; Wang, Z; Shull, G E; Soleimani, M (1997. )Cloning and functional expression of a human kidney Na+:HCO3- cotransporter. The Journal of biological chemistry, ,272 (31 ),19111-4

Amlal, H; Soleimani, M (1997. )K+/NH4+ antiporter: a unique ammonium carrying transporter in the kidney inner medulla. Biochimica et biophysica acta, ,1323 (2 ),319-33

Dos Santos, Ingrid F; Sheriff, Sulaiman; Amlal, Sihame; Ahmed, Rafeeq P H; Thakar, Charuhas V; Amlal, Hassane (2019. )Adenine acts in the kidney as a signaling factor and causes salt- and water-losing nephropathy: early mechanism of adenine-induced renal injury.American journal of physiology. Renal physiology, ,316 (4 ),F743-F757

Honors and Awards

1984 -1988 Government Scholarship for Undergraduate Studies, Morocco

1988 -1994 Government Scholarship for Graduate Studies, Morocco

1991 -1994 Government Scholarship for Graduate Studies form INSERM (National Institute of Health and Medical Research), France

1997 2nd Prize Fellows' Grand Rounds Department of Internal Medicine, University of Cincinnati

Service

University of Cincinnati (Research Committee )Member Type:University/College Service 2009 -To Present

University of Cincinnati (Merit Pay Increase Committee )Member Type:University/College Service 2010 -To Present

Journal of Nephrology and Renal Transplantation (Editorial Board )Member 2009 -To Present

University of Cincinnati (Annual Poster Forum )Judge 2008 -To Present

Department of Internal Medicine, University of Cincinnati (Post-Doctoral Fellows Annual Poster Session )Judge 2009 -To Present

Journal of the American Society of Nephrology (Manuscript ) Reviewer

American Journal of Physiology-Renal Physiology (Manuscript )Reviewer

Kidney International (Manuscript )Reviewer

Acta Physiologica (Manuscript )Reviewer

Biochemica Biophysica Acta (Manuscript )Reviewer

Kidney and Blood Pressure (Manuscript ) Reviewer

Veterans Affairs / Nephrology Study Section (Grant )Reviewer 06-2011 -To Present

ASN (Acid-Base Session )Co-Chair 11-2011

Post Graduate Training and Education

1995-1999 Post Doctoral Fellow, Division of Nephrology and Hypertension, University of Cincinnati, ,Cincinnati, OH

1989-1990 Master's, Renal Physiology and Pathophysiology, University Pierre et Marie Curie (Paris 6), ,Paris, France

1990-1994 Ph.D., Renal Physiology, University Pierre et Marie Curie (Paris 6), ,Paris, France

Keywords

Gluatmine, ion transport, acid-base

Professional Affiliation

1996 -To Present: Member TOKTEN (Transfer of Knowledge Through Expatriate Nationals) Program United Nations / Morocco

Contact Information

Academic - University of Cincinnati College of Medicine
Room 6116
Cincinnati  Ohio, 45267
Phone: 513-558-2880
Fax: 513-558-4309
hassane.amlal@uc.edu