Senu Apewokin

Senu Apewokin

Associate Professor of Clinical

Medical Sciences Building


COM IM Infectious Diseases Division - 0560

Medical Sciences Building
Room 6153B
Cincinnati, Ohio 45267


Bachelor's Degree, Univeristy of Ghana 1998 (Medical Sciences)

Bachelor of Medicine and Surgery (MBChB), University of Ghana Medical School 2002

Residency, Western Pennsylvania Hospital 2007 (Internal Medicine)

Fellowship, University of Alabama at Birmingham 2009 (Infectious Diseases)

Positions and Work Experience

09-30-3013 -09-20-2014 Assist Prof of Medicine, Director of Supportive Care, University of Arkansas for Medical Sciences , Little Rock, Arkansas

06-20-2012 -09-20-2013 Assist Prof of Medicine, Director, Supportive Care Clinical Research, University of Arkansas for Medical Sciences ,

07-20-2014 -BAD DATE Assist Prof of Medicine, Director, Transplant Infectious Diseases, University of Cincinnati , Cincinnati, Ohio

Research and Practice Interests

Infectious Diseases In Transplant Patients

Clinical Focus

Infectious Disease


Infectious Disease

Internal Medicine


American Board of Internal Medicine (Infectious Disease)


American Board of Internal Medicine


Research Support

Grant: #HOPE / U01AI134591 Investigators:Apewokin, Senu 08-01-2018 -07-31-2022 National Institute of Allergy and Infectious Diseases HOPE in Action: A Clinical trial of HIV-to-HIV deceased donor kidnet transplantation Role:PI $3,540.95 Awarded Level:Federal

Grant: #Hope-Liver / U01AI138897 Investigators:Apewokin, Senu 01-01-2019 -07-31-2019 National Institute of Allergy and Infectious Diseases HOPE in Action: A Clinical Trial of HIV-to-HIV Liver Transplantation Role:PI $5,082.19 Awarded Level:Federal

Grant: #P30 ES006096 Investigators:Apewokin, Senu 04-01-2019 -03-31-2020 Centers for Disease Control and Prevention MCRADA - Associations between PFOA exposure and humoral responses to pneumococcal vaccine Role:PI $.00 Active Level:Federal

Grant: #K08CA237735 Investigators:Apewokin, Senu 06-01-2020 -05-31-2025 National Cancer Institute Harnessing Induced Human Intestinal Organoids (iHIOs) and Metagenomics to Unravel Host Immune-microbiota Interactions During Cancer Chemotherapy-associated Clostridium difficile Infections Role:PI $233,957.00 Awarded Level:Federal


Peer Reviewed Publications

Erickson, Stephen W; Raj, Vinay R; Stephens, Owen W; Dhakal, Ishwori; Chavan, Shweta S; Sanathkumar, Naveen; Coleman, Elizabeth Ann; Lee, Jeannette Y; Goodwin, Julia A; Apewokin, Senu; Zhou, Daohong; Epstein, Joshua; Heuck, Christoph J; Vangsted, Annette J (2014. ) Genome-wide scan identifies variant in 2q12.3 associated with risk for multiple myeloma.Blood, , 124 (12 ) ,2001-3

Coleman, Elizabeth Ann; Lee, Jeannette Y; Erickson, Stephen W; Goodwin, Julia A; Sanathkumar, Naveen; Raj, Vinay R; Zhou, Daohong; McKelvey, Kent D; Apewokin, Senu; Stephens, Owen; Enderlin, Carol A; Vangsted, Annette Juul; Reed, Patty J; Anaissie, Elias J (2014. ) GWAS of 972 autologous stem cell recipients with multiple myeloma identifies 11 genetic variants associated with chemotherapy-induced oral mucositis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, ,

Abdallah, Al-ola; Atrash, Shebli; Shahid, Zainab; Jameel, Muzaffar; Grazziutti, Monica; Apewokin, Senu; Kumar, Naveen S; Restrepo, Alejandro; Waheed, Sarah; Van Rhee, Frits; Heuck, Christoph J; Johann, Donald; Barlogie, Bart; Usmani, Saad Z (2014. ) Patterns of central nervous system involvement in relapsed and refractory multiple myeloma.Clinical lymphoma, myeloma & leukemia, , 14 (3 ) ,211-4

Apewokin, Senu; Wontumi, Gold-Marie; Kumar, Naveen S; Matin, Aasiya; Grazziutti, Monica (2014. ) Severe mucositis and Clostridium difficile infection in adult autologous stem cell recipients: another question of the chicken or the egg?.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, , 20 (2 ) ,288

Krishna, S G; Zhao, W; Apewokin, S K; Krishna, K; Chepyala, P; Anaissie, E J (2013. ) Risk factors, preemptive therapy, and antiperistaltic agents for Clostridium difficile infection in cancer patients.Transplant infectious disease : an official journal of the Transplantation Society, , 15 (5 ) ,493-501

Steinbach, William J; Marr, Kieren A; Anaissie, Elias J; Azie, Nkechi; Quan, Shun-Ping; Meier-Kriesche, Herwig-Ulf; Apewokin, Senu; Horn, David L (2012. ) Clinical epidemiology of 960 patients with invasive aspergillosis from the PATH Alliance registry.The Journal of infection, , 65 (5 ) ,453-64

Apewokin, S; Steciuk, M; Griffin, S; Jhala, D (2010. ) Strongyloides hyperinfection diagnosed by bronchoalveolar lavage in an immunocompromized host.Cytopathology : official journal of the British Society for Clinical Cytology, , 21 (5 ) ,345-7

Apewokin, Senu K; Geisler, William M; Bachmann, Laura H (2010. ) Spontaneous resolution of extragenital chlamydial and gonococcal infections prior to therapy.Sexually transmitted diseases, , 37 (5 ) ,343-4

Khan, R; Apewokin, S; Grazziutti, M; Yaccoby, S; Epstein, J; van Rhee, F; Rosenthal, A; Waheed, S; Usmani, S; Atrash, S; Kumar, S; Hoering, A; Crowley, J; Shaughnessy, J D; Barlogie, B (2015. ) Renal insufficiency retains adverse prognostic implications despite renal function improvement following Total Therapy for newly diagnosed multiple myeloma.Leukemia, ,

Apewokin, Senu; Vyas, Keyur; Lester, Laura K; Grazzuitti, Monica; Haselow, Dirk T; Wolfe, Frankie; Roberts, Michelle; Bellamy, William; Kumar, Naveen Sanath; Hunter, Dolris; Lee, Jeannette; Laudadio, Jennifer; Wheeler, J Gary; Bradsher, Robert (2014. ) Influenza a outbreak in an ambulatory stem cell transplant center.Open forum infectious diseases, , 1 (2 ) ,ofu050

Apewokin, Senu; Lee, Jeannette Y; Goodwin, Julia A; McKelvey, Kent D; Stephens, Owen W; Zhou, Daohong; Coleman, Elizabeth Ann (2018. ) Host genetic susceptibility to Clostridium difficile infections in patients undergoing autologous stem cell transplantation: a genome-wide association study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, , 26 (9 ) ,3127-3134

Clancy, Cornelius J; Pappas, Peter G; Vazquez, Jose; Judson, Marc A; Kontoyiannis, Dimitrios P; Thompson, George R; Garey, Kevin W; Reboli, Annette; Greenberg, Richard N; Apewokin, Senu; Lyon, G Marshall; Ostrosky-Zeichner, Luis; Wu, Alan H B; Tobin, Ellis; Nguyen, M Hong; Caliendo, Angela M (2018. ) Detecting Infections Rapidly and Easily for Candidemia Trial, Part 2 (DIRECT2): A Prospective, Multicenter Study of the T2Candida Panel.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, , 66 (11 ) ,1678-1686

Bari, Khurram; Luckett, Keith; Kaiser, Tiffany; Diwan, Tayyab; Cuffy, Madison; Schoech, Michael R; Safdar, Kamran; Blackard, Jason T; Apewokin, Senu; Paterno, Flavio; Sherman, Kenneth E; Zucker, Stephen D; Anwar, Nadeem; Shah, Shimul A (2018. ) Hepatitis C transmission from seropositive, nonviremic donors to non-hepatitis C liver transplant recipients.Hepatology (Baltimore, Md.), , 67 (5 ) ,1673-1682

Kamal, M; Apewokin, S; Anand, M; Abu Jawdeh, B G; Govil, A; Sheikh, M M; Shah, S (2017. ) Late-Onset Allograft Aspergillosis in an HIV-Positive Renal Transplant Recipient: A Case Report.Transplantation proceedings, , 49 (7 ) ,1570-1573

Vargas, Edwin; Apewokin, Senu; Madan, Rajat (2017. ) Role of the leukocyte response in normal and immunocompromised host after Clostridium difficile infection.Anaerobe, , 45 ,101-105

Matin, Aasiya; Sharma, Smriti; Mathur, Pankaj; Apewokin, Senu K (2017. ) Myelosuppression-sparing treatment of central nervous system nocardiosis in a multiple myeloma patient utilizing a tedizolid-based regimen: a case report.International journal of antimicrobial agents, , 49 (4 ) ,488-492

Apewokin, S; Goodwin, J A; Lee, J Y; Erickson, S W; Sanathkumar, N; Raj, V R; Zhou, D; McKelvey, K D; Stephens, O; Coleman, E A (2015. ) Contribution of Clostridium difficile infection to the development of lower gastrointestinal adverse events during autologous stem cell transplantation.Transplant infectious disease : an official journal of the Transplantation Society, , 17 (4 ) ,566-73

Baddley, John W; Apewokin, Senu (2008. ) Prevention of Invasive Aspergillosis in High-Risk Patients: Universal Versus Preemptive, Targeted Treatment.Current fungal infection reports, , 2 ,61-68


Invited Presentations

Senu Apewokin (03-20-2013. ) (In Press. ) Infection Prevention in Multiple Myeloma patients . Level:International

Senu Apewokin,S. Susanibaradaniya MD, A. Pande, S. Parajuli MD, MD, Monica Grazzuitti MD (09-20-2015. ) (In Progress. ) Procalcitonin Guided Antimicrobial Stewardship During Engraftment in Autologous Stemcell Transplant Recipients: A Prospective Cohort Study of 100 pts .ICAAC 2015 ASM’s Interscience Conference of Antimicrobial Agents and Chemotherapy, San Diego, USA, San Diego. Conference. . Level:International


Department of Defense (Healthcare-Associated Infection Reduction (HCAIR) ) Reviewer Type:Grant Panel Level:National 05-19-2015 -To Present

Visual Dx : WWW.VISUALDX.COM (Infectious Disease editorial board ) Editorial Board Member Type:Editorial Service Level:International 07-01-2009 -To Present

T1 Grant reviews CTSA (T1 study section ) Member Type:Grant Panel Level:Local 01-15-2015

World Journal of Gastroenterology Reviewer Type:Editorial Service Level:International 04-01-2014

The American Journal of Medical Sciences Reviewer Type:Editorial Service Level:National 10-01-2014

Contact Information

Academic - Medical Sciences Building
Room 6153B
Cincinnati  Ohio, 45267
Phone: 513-558-4704
Fax: 513-558-2089