Senu Apewokin

Senu Apewokin , MD

Associate Professor of Clinical

Medical Sciences Building
Room 6153B
231 Albert Sabin Way
Cincinnati, Ohio 45267
Phone 513-558-4704
Fax 513-558-2089


Bachelor's Degree: Univeristy of Ghana 1998 (Medical Sciences)

Bachelor of Medicine and Surgery (MBChB): University of Ghana Medical School 2002

Residency: Western Pennsylvania Hospital 2007 (Internal Medicine)

Fellowship: University of Alabama at Birmingham 2009 (Infectious Diseases)

Clinical Interests

Infectious Disease

HIV/AIDS (Human immunodeficiency virus)


Infectious Diseases

Internal Medicine

Research and Practice Interests

Infectious Diseases In Transplant Patients

Positions and Work Experience

09-30-3013 -09-20-2014 Assist Prof of Medicine, Director of Supportive Care, University of Arkansas for Medical Sciences , Little Rock, Arkansas

06-20-2012 -09-20-2013 Assist Prof of Medicine, Director, Supportive Care Clinical Research, University of Arkansas for Medical Sciences ,

07-20-2014 -BAD DATE Assist Prof of Medicine, Director, Transplant Infectious Diseases, University of Cincinnati , Cincinnati, Ohio

Research Support

Grant: #HOPE / U01AI134591 Investigators:Apewokin, Senu 08-01-2018 -07-31-2022 National Institute of Allergy and Infectious Diseases HOPE in Action: A Clinical trial of HIV-to-HIV deceased donor kidnet transplantation Role:PI $3,540.95 Awarded Level:Federal

Grant: #Hope-Liver / U01AI138897 Investigators:Apewokin, Senu 01-01-2019 -07-31-2019 National Institute of Allergy and Infectious Diseases HOPE in Action: A Clinical Trial of HIV-to-HIV Liver Transplantation Role:PI $5,082.19 Awarded Level:Federal

Grant: #P30 ES006096 Investigators:Apewokin, Senu 04-01-2019 -03-31-2020 Centers for Disease Control and Prevention MCRADA - Associations between PFOA exposure and humoral responses to pneumococcal vaccine Role:PI $.00 Active Level:Federal

Grant: #K08CA237735 Investigators:Apewokin, Senu 06-01-2020 -05-31-2025 National Cancer Institute Harnessing Induced Human Intestinal Organoids (iHIOs) and Metagenomics to Unravel Host Immune-microbiota Interactions During Cancer Chemotherapy-associated Clostridium difficile Infections Role:PI $233,957.00 Awarded Level:Federal


Peer Reviewed Publications

Erickson, Stephen W; Raj, Vinay R; Stephens, Owen W; Dhakal, Ishwori; Chavan, Shweta S; Sanathkumar, Naveen; Coleman, Elizabeth Ann; Lee, Jeannette Y; Goodwin, Julia A; Apewokin, Senu; Zhou, Daohong; Epstein, Joshua; Heuck, Christoph J; Vangsted, Annette J (2014. ) Genome-wide scan identifies variant in 2q12.3 associated with risk for multiple myeloma.Blood, , 124 (12 ) ,2001-3 More Information

Coleman, Elizabeth Ann; Lee, Jeannette Y; Erickson, Stephen W; Goodwin, Julia A; Sanathkumar, Naveen; Raj, Vinay R; Zhou, Daohong; McKelvey, Kent D; Apewokin, Senu; Stephens, Owen; Enderlin, Carol A; Vangsted, Annette Juul; Reed, Patty J; Anaissie, Elias J (2014. ) GWAS of 972 autologous stem cell recipients with multiple myeloma identifies 11 genetic variants associated with chemotherapy-induced oral mucositis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, , More Information

Abdallah, Al-ola; Atrash, Shebli; Shahid, Zainab; Jameel, Muzaffar; Grazziutti, Monica; Apewokin, Senu; Kumar, Naveen S; Restrepo, Alejandro; Waheed, Sarah; Van Rhee, Frits; Heuck, Christoph J; Johann, Donald; Barlogie, Bart; Usmani, Saad Z (2014. ) Patterns of central nervous system involvement in relapsed and refractory multiple myeloma.Clinical lymphoma, myeloma & leukemia, , 14 (3 ) ,211-4 More Information

Apewokin, Senu; Wontumi, Gold-Marie; Kumar, Naveen S; Matin, Aasiya; Grazziutti, Monica (2014. ) Severe mucositis and Clostridium difficile infection in adult autologous stem cell recipients: another question of the chicken or the egg?.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, , 20 (2 ) ,288 More Information

Krishna, S G; Zhao, W; Apewokin, S K; Krishna, K; Chepyala, P; Anaissie, E J (2013. ) Risk factors, preemptive therapy, and antiperistaltic agents for Clostridium difficile infection in cancer patients.Transplant infectious disease : an official journal of the Transplantation Society, , 15 (5 ) ,493-501 More Information

Steinbach, William J; Marr, Kieren A; Anaissie, Elias J; Azie, Nkechi; Quan, Shun-Ping; Meier-Kriesche, Herwig-Ulf; Apewokin, Senu; Horn, David L (2012. ) Clinical epidemiology of 960 patients with invasive aspergillosis from the PATH Alliance registry.The Journal of infection, , 65 (5 ) ,453-64 More Information

Apewokin, S; Steciuk, M; Griffin, S; Jhala, D (2010. ) Strongyloides hyperinfection diagnosed by bronchoalveolar lavage in an immunocompromized host.Cytopathology : official journal of the British Society for Clinical Cytology, , 21 (5 ) ,345-7 More Information

Apewokin, Senu K; Geisler, William M; Bachmann, Laura H (2010. ) Spontaneous resolution of extragenital chlamydial and gonococcal infections prior to therapy.Sexually transmitted diseases, , 37 (5 ) ,343-4 More Information

Khan, R; Apewokin, S; Grazziutti, M; Yaccoby, S; Epstein, J; van Rhee, F; Rosenthal, A; Waheed, S; Usmani, S; Atrash, S; Kumar, S; Hoering, A; Crowley, J; Shaughnessy, J D; Barlogie, B (2015. ) Renal insufficiency retains adverse prognostic implications despite renal function improvement following Total Therapy for newly diagnosed multiple myeloma.Leukemia, , More Information

Apewokin, Senu; Vyas, Keyur; Lester, Laura K; Grazzuitti, Monica; Haselow, Dirk T; Wolfe, Frankie; Roberts, Michelle; Bellamy, William; Kumar, Naveen Sanath; Hunter, Dolris; Lee, Jeannette; Laudadio, Jennifer; Wheeler, J Gary; Bradsher, Robert (2014. ) Influenza a outbreak in an ambulatory stem cell transplant center.Open forum infectious diseases, , 1 (2 ) ,ofu050 More Information

Apewokin, Senu; Lee, Jeannette Y; Goodwin, Julia A; McKelvey, Kent D; Stephens, Owen W; Zhou, Daohong; Coleman, Elizabeth Ann (2018. ) Host genetic susceptibility to Clostridium difficile infections in patients undergoing autologous stem cell transplantation: a genome-wide association study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, , 26 (9 ) ,3127-3134 More Information

Clancy, Cornelius J; Pappas, Peter G; Vazquez, Jose; Judson, Marc A; Kontoyiannis, Dimitrios P; Thompson, George R; Garey, Kevin W; Reboli, Annette; Greenberg, Richard N; Apewokin, Senu; Lyon, G Marshall; Ostrosky-Zeichner, Luis; Wu, Alan H B; Tobin, Ellis; Nguyen, M Hong; Caliendo, Angela M (2018. ) Detecting Infections Rapidly and Easily for Candidemia Trial, Part 2 (DIRECT2): A Prospective, Multicenter Study of the T2Candida Panel.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, , 66 (11 ) ,1678-1686 More Information

Bari, Khurram; Luckett, Keith; Kaiser, Tiffany; Diwan, Tayyab; Cuffy, Madison; Schoech, Michael R; Safdar, Kamran; Blackard, Jason T; Apewokin, Senu; Paterno, Flavio; Sherman, Kenneth E; Zucker, Stephen D; Anwar, Nadeem; Shah, Shimul A (2018. ) Hepatitis C transmission from seropositive, nonviremic donors to non-hepatitis C liver transplant recipients.Hepatology (Baltimore, Md.), , 67 (5 ) ,1673-1682 More Information

Kamal, M; Apewokin, S; Anand, M; Abu Jawdeh, B G; Govil, A; Sheikh, M M; Shah, S (2017. ) Late-Onset Allograft Aspergillosis in an HIV-Positive Renal Transplant Recipient: A Case Report.Transplantation proceedings, , 49 (7 ) ,1570-1573 More Information

Vargas, Edwin; Apewokin, Senu; Madan, Rajat (2017. ) Role of the leukocyte response in normal and immunocompromised host after Clostridium difficile infection.Anaerobe, , 45 ,101-105 More Information

Matin, Aasiya; Sharma, Smriti; Mathur, Pankaj; Apewokin, Senu K (2017. ) Myelosuppression-sparing treatment of central nervous system nocardiosis in a multiple myeloma patient utilizing a tedizolid-based regimen: a case report.International journal of antimicrobial agents, , 49 (4 ) ,488-492 More Information

Apewokin, S; Goodwin, J A; Lee, J Y; Erickson, S W; Sanathkumar, N; Raj, V R; Zhou, D; McKelvey, K D; Stephens, O; Coleman, E A (2015. ) Contribution of Clostridium difficile infection to the development of lower gastrointestinal adverse events during autologous stem cell transplantation.Transplant infectious disease : an official journal of the Transplantation Society, , 17 (4 ) ,566-73 More Information

Baddley, John W; Apewokin, Senu (2008. ) Prevention of Invasive Aspergillosis in High-Risk Patients: Universal Versus Preemptive, Targeted Treatment.Current fungal infection reports, , 2 ,61-68 More Information

Mendy, Angelico; Wu, Xiao; Keller, Jason L; Fassler, Cecily S; Apewokin, Senu; Mersha, Tesfaye B; Xie, Changchun; Pinney, Susan M (2021. ) Long-term exposure to fine particulate matter and hospitalization in COVID-19 patients.Respiratory medicine, , 178 ,106313 More Information

Mendy, Angelico; Keller, Jason L; Apewokin, Senu; Morrow, Ardythe L (2020. ) Is Blood Type Associated with COVID-19 Severity?.medRxiv : the preprint server for health sciences, , More Information

Mendy, Angelico; Apewokin, Senu; Wells, Anjanette A; Morrow, Ardythe L (2020. ) Factors Associated with Hospitalization and Disease Severity in a Racially and Ethnically Diverse Population of COVID-19 Patients.medRxiv : the preprint server for health sciences, , More Information

Apewokin, Senu; Onyishi, Ngozi (2020. ) Influenza-like Illness Definition Pertaining to Clinical Practice Guidelines on the Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, , 70 (12 ) ,2749 More Information

Pavia, Andrew T; Ison, Michael G; Wolfe, Cameron R; Uyeki, Timothy M (2020. ) Response to Apewokin and Onyishi.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, , 70 (12 ) ,2749-2750 More Information

Durand, Christine M; Werbel, William; Doby, Brianna; Brown, Diane; Desai, Niraj M; Malinis, Maricar; Price, Jennifer; Chin-Hong, Peter; Mehta, Shikha; Friedman-Moraco, Rachel; Turgeon, Nicole A; Gilbert, Alexander; Morris, Michele I; Stosor, Valentina; Elias, Nahel; Aslam, Saima; Santos, Carlos A Q; Hand, Jonathan M; Husson, Jennifer; Pruett, Timothy L; Agarwal, Avinash; Adebiyi, Oluwafisayo; Pereira, Marcus; Small, Catherine B; Apewokin, Senu; Heun Lee, Dong; Haidar, Ghady; Blumberg, Emily; Mehta, Sapna A; Huprikar, Shirish; Florman, Sander S; Redd, Andrew D; Tobian, Aaron A R; Segev, Dorry L (2020. ) Clarifying the HOPE Act landscape: The challenge of donors with false-positive HIV results.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, , 20 (2 ) ,617-619 More Information

Luckett, Keith; Kaiser, Tiffany E; Bari, Khurram; Safdar, Kamran; Schoech, Michael R; Apewokin, Senu; Diwan, Tayyab S; Cuffy, Madison C; Anwar, Nadeem; Shah, Shimul A (2019. ) Use of Hepatitis C Virus Antibody-Positive Donor Livers in Hepatitis C Nonviremic Liver Transplant Recipients.Journal of the American College of Surgeons, , 228 (4 ) ,560-567 More Information

Apewokin, S; Madan, R; Restrepo, A; Hemmige, V S; Arora, S (2018. ) Clinical and Health Care Utilization Outcomes of Kidney Transplantation in HIV-Positive Recipients: A Nationwide Analysis From 2008-2013.Transplantation proceedings, , 50 (10 ) ,3361-3366 More Information

Kharofa, Jordan; Apewokin, Senu; Alenghat, Theresa; Ollberding, Nicholas J (2022. ) Metagenomic analysis of the fecal microbiome in colorectal cancer patients compared to healthy controls as a function of age.Cancer medicine, , More Information

Hillenbrand, Molly; Mendy, Angelico; Patel, Kavya; Wilkinson, Racheal; Liao, Siyun; Robertson, Jamie; Apewokin, Senu (2022. ) The Incidence of Ocular Complications in Candidemic Patients and Implications for the Practice of Routine ?Eye Exams.Open forum infectious diseases, , 9 (4 ) ,ofac045 More Information

Durand, Christine M; Florman, Sander; Motter, Jennifer D; Brown, Diane; Ostrander, Darin; Yu, Sile; Liang, Tao; Werbel, William A; Cameron, Andrew; Ottmann, Shane; Hamilton, James P; Redd, Andrew D; Bowring, Mary G; Eby, Yolanda; Fernandez, Reinaldo E; Doby, Brianna; Labo, Nazzarena; Whitby, Denise; Miley, Wendell; Friedman-Moraco, Rachel; Turgeon, Nicole; Price, Jennifer C; Chin-Hong, Peter; Stock, Peter; Stosor, Valentina; Kirchner, Varvara A; Pruett, Timothy; Wojciechowski, David; Elias, Nahel; Wolfe, Cameron; Quinn, Thomas C; Odim, Jonah; Morsheimer, Megan; Mehta, Sapna A; Rana, Meenakshi M; Huprikar, Shirish; Massie, Allan; Tobian, Aaron A R; Segev, Dorry L (2022. ) HOPE in action: A prospective multicenter pilot study of liver transplantation from donors with HIV to recipients with HIV.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, , 22 (3 ) ,853-864 More Information

Jose, Arun; Apewokin, Senu; Hussein, Walaa E; Ollberding, Nicholas J; Elwing, Jean M; Haslam, David B (2022. ) A unique gut microbiota signature in pulmonary arterial hypertension: A pilot study.Pulmonary circulation, , 12 (1 ) ,e12051 More Information

Mendy, Angelico; Wu, Xiao; Keller, Jason L; Fassler, Cecily S; Apewokin, Senu; Mersha, Tesfaye B; Xie, Changchun; Pinney, Susan M (2021. ) Air pollution and the pandemic: Long-term PM2.5 exposure and disease severity in COVID-19 patients.Respirology (Carlton, Vic.), , 26 (12 ) ,1181-1187 More Information


Invited Presentations

Senu Apewokin (03-20-2013. ) (In Press. ) Infection Prevention in Multiple Myeloma patients . Level:International

Senu Apewokin,S. Susanibaradaniya MD, A. Pande, S. Parajuli MD, MD, Monica Grazzuitti MD (09-20-2015. ) (In Progress. ) Procalcitonin Guided Antimicrobial Stewardship During Engraftment in Autologous Stemcell Transplant Recipients: A Prospective Cohort Study of 100 pts .ICAAC 2015 ASM’s Interscience Conference of Antimicrobial Agents and Chemotherapy, San Diego, USA, San Diego. Conference. . Level:International


Department of Defense (Healthcare-Associated Infection Reduction (HCAIR) ) Reviewer Type:Grant Panel Level:National 05-19-2015 -To Present

Visual Dx : WWW.VISUALDX.COM (Infectious Disease editorial board ) Editorial Board Member Type:Editorial Service Level:International 07-01-2009 -To Present

T1 Grant reviews CTSA (T1 study section ) Member Type:Grant Panel Level:Local 01-15-2015

World Journal of Gastroenterology Reviewer Type:Editorial Service Level:International 04-01-2014

The American Journal of Medical Sciences Reviewer Type:Editorial Service Level:National 10-01-2014

Contact Information

Academic - Medical Sciences Building
Room 6153B
Cincinnati  Ohio, 45267
Phone: 513-558-4704
Fax: 513-558-2089