Lesley Arnold

Lesley Arnold , MD

Professor

Director of the Women’s Health Research Program

Stetson Building
Suite 3200
260 Stetson Street
Cincinnati, Ohio 45219
Phone 513-558-7700
Email lesley.arnold@uc.edu

Professional Summary

Dr. Arnold is a Professor of Psychiatry. She is the Director of the Women’s Health Research Program for the Department of Psychiatry and conducts research full time. Dr. Arnold graduated from Cornell University with a B.A. in 1981 and received her M.D. from the University of Cincinnati College of Medicine in 1986.

Her research interests include Fibromyalgia, Chronic Pain, Women’s Health, and Mood and Anxiety Disorders.

Education

Bachelor's Degree: Cornell University

Medical Degree: University of Cincinnati College of Medicine

Residency: University of Cincinnati College of Medicine

Certifications

American Board of Psychiatry and Neurology (Psychiatry) (Certification Date: 01-30-1992 )

Clinical Interests

Psychiatry

Specialities

Psychiatry

Research and Practice Interests

Research interests include Fibromyalgia, Chronic Pain, Women’s Health, and Mood and Anxiety Disorders.

Research Support

Grant: #CHMC 397 / AR050028 Investigators:Arnold, Lesley 07-01-2004 -06-30-2009 National Institute of Arthritis, Musculoskeletal and Skin Disease Randomized Clinical Trial in Juvenile Fibromyalgia Role:PI $81,120.00 Closed Level:Federal

Grant: #5-N01-AR-9-2235-04-A0-S0-E0 Investigators:Arnold, Lesley 09-30-2000 -09-30-2004 National Institute of Arthritis, Musculoskeletal and Skin Disease Fibromyalgia Family Study Role:PI $24,607.00 Closed Level:Federal

Investigators:Arnold, Lesley 09-30-2002 -06-30-2006 National Institute of Arthritis, Musculoskeletal and Skin Disease Phase II Double-Blind Placebo-Controlled Trial of Gabapentin in the Treatment of Fibromyalgia Role:PI $2,474,716.02 Closed Level:Federal

Grant: #5-R01-AR-46054-03-A0-S0-E0 Investigators:Arnold, Lesley 07-01-1999 -06-30-2003 National Institute of Arthritis, Musculoskeletal and Skin Disease A Controlled Family Study in Patients with Fibromyalgia Role:PI $648,568.00 Closed Level:Federal

Grant: #R01 AR053207 Investigators:Arnold, Lesley 05-18-2007 -04-30-2012 National Institute of Arthritis, Musculoskeletal and Skin Disease Development of Fibromyalgia Responder Index Role:PI $1,062,117.00 Closed Level:Federal

Grant: #CHMC 105591 / R01 AR054842 Investigators:Arnold, Lesley 08-01-2009 -07-31-2013 National Institute of Arthritis, Musculoskeletal and Skin Disease Longitudinal Determination of Outcomes of Adolescents with Fibromyalgia Role:PI $72,704.00 Active Level:Federal

Grant: #CK #1006212888 Investigators:Arnold, Lesley 07-01-2010 -06-30-2011 Pfizer, Inc. Pfizer Visiting Professorships in Neurology/Psychiatry Role:PI $7,500.00 Closed Level:Industry

Grant: #Midwestern Pain Consortium - Consortium Agreement Investigators:Arnold, Lesley 12-04-2013 -12-03-2018 Eli Lilly and Company Midwestern Pain Consortium - Consortium Agreement Role:PI $.00 Active Level:Industry

Grant: #Midwestern Pain Consortium - Lilly Member Organization Agmt Investigators:Arnold, Lesley 12-04-2013 -12-03-2018 Eli Lilly and Company Midwestern CTSA Pain Consortium - Lilly Member Organization Agmt Role:PI $400,000.00 Active Level:Industry

Publications

Peer Reviewed Publications

Kashikar-Zuck, Susmita; Johnston, Megan; Ting, Tracy V; Graham, Brent T; Lynch-Jordan, Anne M; Verkamp, Emily; Passo, Murray; Schikler, Kenneth N; Hashkes, Philip J; Spalding, Steven; Banez, Gerard; Richards, Margaret M; Powers, Scott W; Arnold, Lesley M; Lovell, Daniel (2010. ) Relationship between School Absenteeism and Depressive Symptoms among Adolescents with Juvenile Fibromyalgia.Journal of pediatric psychology, , 35 (9 ) ,996-1004 More Information

Arnold, Lesley M; Clauw, Daniel; Wang, Fujun; Ahl, Jonna; Gaynor, Paula J; Wohlreich, Madelaine M (2010. ) Flexible Dosed Duloxetine in the Treatment of Fibromyalgia: A Randomized, Double-blind, Placebo-controlled Trial.The Journal of rheumatology, , More Information

Kashikar-Zuck, Susmita; Flowers, Stacy R; Verkamp, Emily; Ting, Tracy V; Lynch-Jordan, Anne M; Graham, T Brent; Passo, Murray; Schikler, Kenneth N; Hashkes, Philip J; Spalding, Steven; Banez, Gerard; Richards, Margaret M; Powers, Scott W; Arnold, Lesley M; Lovell, Daniel (2010. ) Actigraphy-based physical activity monitoring in adolescents with juvenile primary fibromyalgia syndrome.The journal of pain : official journal of the American Pain Society, , 11 (9 ) ,885-93 More Information

Arnold, Lesley M; Clauw, Daniel J (2010. ) Fibromyalgia syndrome: practical strategies for improving diagnosis and patient outcomes.The American journal of medicine, , 123 (6 ) ,S2 More Information

Arnold, Lesley M (2010. ) The pathophysiology, diagnosis and treatment of fibromyalgia.The Psychiatric clinics of North America, , 33 (2 ) ,375-408 More Information

Arnold, Lesley M; Gendreau, R Michael; Palmer, Robert H; Gendreau, Judy F; Wang, Yong (2010. ) Efficacy and safety of milnacipran 100 mg/day in patients with fibromyalgia: Results of a randomized, double-blind, placebo-controlled trial.Arthritis and rheumatism, , More Information

Arnold, Lesley; Mease, Philip; Silverman, Stuart (2010. ) Pregabalin: an alpha2-delta (alpha2-delta) ligand for the management of fibromyalgia. The American journal of managed care, , 16 (5 Suppl ) ,S138-43

Arnold, Lesley M (2009. ) Strategies for managing fibromyalgia.The American journal of medicine, , 122 (12 Suppl ) ,S31-43 More Information

Hudson, James I; Arnold, Lesley M; Bradley, Laurence A; Choy, Ernest H S; Mease, Philip J; Wang, Fujun; Ahl, Jonna; Wohlreich, Madelaine M (2009. ) What makes patients with fibromyalgia feel better? Correlations between Patient Global Impression of Improvement and changes in clinical symptoms and function: a pooled analysis of 4 randomized placebo-controlled trials of duloxetine.The Journal of rheumatology, , 36 (11 ) ,2517-22 More Information

Arnold, Lesley M (2009. ) Advances in the management of fibromyalgia. CNS spectrums, , 14 (10 Suppl 8 ) ,12-6; discussion 17-

Choy, Ernest H; Arnold, Lesley M; Clauw, Daniel J; Crofford, Leslie J; Glass, Jennifer M; Simon, Lee S; Martin, Susan A; Strand, C Vibeke; Williams, David A; Mease, Philip J (2009. ) Content and criterion validity of the preliminary core dataset for clinical trials in fibromyalgia syndrome.The Journal of rheumatology, , 36 (10 ) ,2330-4 More Information

Mease, Philip; Arnold, Lesley M; Choy, Ernest H; Clauw, Daniel J; Crofford, Leslie J; Glass, Jennifer M; Martin, Susan A; Morea, Jessica; Simon, Lee; Strand, C Vibeke; Williams, David A (2009. ) Fibromyalgia syndrome module at OMERACT 9: domain construct.The Journal of rheumatology, , 36 (10 ) ,2318-29 More Information

Arnold, Lesley M; Hudson, James I; Wang, Fujun; Wohlreich, Madelaine M; Prakash, Apurva; Kajdasz, Daniel K; Chappell, Amy S Comparisons of the efficacy and safety of duloxetine for the treatment of fibromyalgia in patients with versus without major depressive disorder.The Clinical journal of pain, , 25 (6 ) ,461-8 More Information

Arnold, Lesley M (2009. ) Pain and the brain: chronic widespread pain. The Journal of clinical psychiatry, , 70 (4 ) ,e10

Arnold, Lesley M; Bradley, Laurence A; Clauw, Daniel J; Glass, Jennifer M; Goldenberg, Don L (2008. ) Multidisciplinary care and stepwise treatment for fibromyalgia. The Journal of clinical psychiatry, , 69 (12 ) ,e35

Arnold, Lesley M; Clauw, Daniel J; Wohlreich, Madelaine M; Wang, Fujun; Ahl, Jonna; Gaynor, Paula J; Chappell, Amy S (2009. ) Efficacy of duloxetine in patients with fibromyalgia: pooled analysis of 4 placebo-controlled clinical trials.Primary care companion to the Journal of clinical psychiatry, , 11 (5 ) ,237-44 More Information

Arnold, Lesley M; Bradley, Laurence A; Clauw, Daniel J; Glass, Jennifer M; Goldenberg, Don L (2008. ) Evaluating and diagnosing fibromyalgia and comorbid psychiatric disorders. The Journal of clinical psychiatry, , 69 (10 ) ,e28

Arnold, Lesley M; Jain, Rakesh; Glazer, William M (2008. ) Pain and the brain. The Journal of clinical psychiatry, , 69 (9 ) ,e25

Arnold, Lesley M; Meyers, Adam L; Sunderajan, Prabha; Montano, C Brendan; Kass, Ethan; Trivedi, Madhukar; Wohlreich, Madelaine M The effect of pain on outcomes in a trial of duloxetine treatment of major depressive disorder.Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, , 20 (4 ) ,187-93 More Information

Arnold, Lesley M; Crofford, Leslie J; Mease, Philip J; Burgess, Somali Misra; Palmer, Susan C; Abetz, Linda; Martin, Susan A (2008. ) Patient perspectives on the impact of fibromyalgia.Patient education and counseling, , 73 (1 ) ,114-20 More Information

Arnold, Lesley M; Russell, I Jon; Diri, E W; Duan, W Rachel; Young, James P; Sharma, Uma; Martin, Susan A; Barrett, Jeannette A; Haig, George (2008. ) A 14-week, randomized, double-blinded, placebo-controlled monotherapy trial of pregabalin in patients with fibromyalgia.The journal of pain : official journal of the American Pain Society, , 9 (9 ) ,792-805 More Information

Mease, Phillip J; Arnold, Lesley M; Crofford, Leslie J; Williams, David A; Russell, I Jon; Humphrey, Louise; Abetz, Linda; Martin, Susan A (2008. ) Identifying the clinical domains of fibromyalgia: contributions from clinician and patient Delphi exercises.Arthritis and rheumatism, , 59 (7 ) ,952-60 More Information

Russell, I Jon; Mease, Philip J; Smith, Timothy R; Kajdasz, Daniel K; Wohlreich, Madelaine M; Detke, Michael J; Walker, Daniel J; Chappell, Amy S; Arnold, Lesley M (2008. ) Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial.Pain, , 136 (3 ) ,432-44 More Information

Arnold, Lesley M Understanding fatigue in major depressive disorder and other medical disorders.Psychosomatics, , 49 (3 ) ,185-90 More Information

Mease, Philip J; Russell, I Jon; Arnold, Lesley M; Florian, Hana; Young, James P; Martin, Susan A; Sharma, Uma (2008. ) A randomized, double-blind, placebo-controlled, phase III trial of pregabalin in the treatment of patients with fibromyalgia. The Journal of rheumatology, , 35 (3 ) ,502-14

Lawrence, Reva C; Felson, David T; Helmick, Charles G; Arnold, Lesley M; Choi, Hyon; Deyo, Richard A; Gabriel, Sherine; Hirsch, Rosemarie; Hochberg, Marc C; Hunder, Gene G; Jordan, Joanne M; Katz, Jeffrey N; Kremers, Hilal Maradit; Wolfe, Frederick (2008. ) Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II.Arthritis and rheumatism, , 58 (1 ) ,26-35 More Information

Arnold, Lesley M (2008. ) Management of fibromyalgia and comorbid psychiatric disorders. The Journal of clinical psychiatry, , 69 Suppl 2 ,14-9

Arnold, Lesley M; Crofford, Leslie J; Martin, Susan A; Young, James P; Sharma, Uma The effect of anxiety and depression on improvements in pain in a randomized, controlled trial of pregabalin for treatment of fibromyalgia.Pain medicine (Malden, Mass.), , 8 (8 ) ,633-8 More Information

Arnold, Lesley M; Pritchett, Yili Lu; D'Souza, Deborah N; Kajdasz, Daniel K; Iyengar, Smriti; Wernicke, Joachim F (2007. ) Duloxetine for the treatment of fibromyalgia in women: pooled results from two randomized, placebo-controlled clinical trials.Journal of women's health (2002), , 16 (8 ) ,1145-56 More Information

Arnold, Lesley M (2007. ) Duloxetine and other antidepressants in the treatment of patients with fibromyalgia.Pain medicine (Malden, Mass.), , 8 Suppl 2 ,S63-74 More Information

Pigott, Teresa A; Prakash, Apurva; Arnold, Lesley M; Aaronson, Scott T; Mallinckrodt, Craig H; Wohlreich, Madelaine M (2007. ) Duloxetine versus escitalopram and placebo: an 8-month, double-blind trial in patients with major depressive disorder.Current medical research and opinion, , 23 (6 ) ,1303-18 More Information

Mease, Philip; Arnold, Lesley M; Bennett, Robert; Boonen, Annelies; Buskila, Dan; Carville, Serena; Chappell, Amy; Choy, Ernest; Clauw, Daniel; Dadabhoy, Dina; Gendreau, Michael; Goldenberg, Don; Littlejohn, Geoffrey; Martin, Susan; Perera, Philip; Russell, I Jon; Simon, Lee; Spaeth, Michael; Williams, David; Crofford, Leslie (2007. ) Fibromyalgia syndrome. The Journal of rheumatology, , 34 (6 ) ,1415-25

Arnold, Lesley M; Goldenberg, Don L; Stanford, Sharon B; Lalonde, Justine K; Sandhu, H S; Keck, Paul E; Welge, Jeffrey A; Bishop, Fred; Stanford, Kevin E; Hess, Evelyn V; Hudson, James I (2007. ) Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial.Arthritis and rheumatism, , 56 (4 ) ,1336-44 More Information

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer (2007. ) Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania.Archives of general psychiatry, , 64 (1 ) ,57-64 More Information

Arnold, Lesley M; Hudson, James I; Keck, Paul E; Auchenbach, Megan B; Javaras, Kristin N; Hess, Evelyn V (2006. ) Comorbidity of fibromyalgia and psychiatric disorders. The Journal of clinical psychiatry, , 67 (8 ) ,1219-25

Arnold, Lesley M (2006. ) Management of psychiatric comorbidity in fibromyalgia. Current psychiatry reports, , 8 (3 ) ,241-5

Bennett, Aurora J; Arnold, Lesley M; Welge, Jeffrey A Use of standardized patients during a psychiatry clerkship.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry, , 30 (3 ) ,185-90 More Information

Arnold, Lesley M (2006. ) Biology and therapy of fibromyalgia. New therapies in fibromyalgia.Arthritis research & therapy, , 8 (4 ) ,212 More Information

Arnold, Lesley M; Rosen, Amy; Pritchett, Yili Lu; D'Souza, Deborah N; Goldstein, David J; Iyengar, Smriti; Wernicke, Joachim F (2005. ) A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder.Pain, , 119 (1-3 ) ,5-15 More Information

Arnold, Lesley M (2005. ) The nature of painful and somatic complaints in depressive disorders. CNS spectrums, , 10 (12 Suppl 19 ) ,4-5

Bennett, Aurora J; Roman, Brenda; Arnold, Lesley M; Kay, Jerald; Goldenhar, Linda M Professionalism deficits among medical students: models of identification and intervention.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry, , 29 (5 ) ,426-32 More Information

Mease, Philip J; Clauw, Daniel J; Arnold, Lesley M; Goldenberg, Don L; Witter, James; Williams, David A; Simon, Lee S; Strand, C Vibeke; Bramson, Candace; Martin, Susan; Wright, Timothy M; Littman, Bruce; Wernicke, J F; Gendreau, R Michael; Crofford, Leslie J (2005. ) Fibromyalgia syndrome. The Journal of rheumatology, , 32 (11 ) ,2270-7

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer (2005. ) Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania.Archives of general psychiatry, , 62 (8 ) ,851-8 More Information

Hudson, James I; Arnold, Lesley M; Keck, Paul E; Auchenbach, Megan B; Pope, Harrison G (2004. ) Family study of fibromyalgia and affective spectrum disorder.Biological psychiatry, , 56 (11 ) ,884-91 More Information

Arnold, Lesley M; Hudson, James I (2004. ) Comment on: Familial aggregation of depression in fibromyalgia: a community-based test of alternative hypotheses, Raphael et al., Pain 110 (2004) 449-460.Pain, , 112 (3 ) ,409-10; author reply More Information

McElroy, Susan L; Shapira, Nathan A; Arnold, Lesley M; Keck, Paul E; Rosenthal, Norman R; Wu, Shu-Chen; Capece, Julie A; Fazzio, Lydia; Hudson, James I (2004. ) Topiramate in the long-term treatment of binge-eating disorder associated with obesity. The Journal of clinical psychiatry, , 65 (11 ) ,1463-9

Bennett, Aurora J; Arnold, Lesley M (2004. ) Use of a computerized evaluation system in a psychiatry clerkship.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry, , 28 (3 ) ,197-203 More Information

Arnold, Lesley M; Lu, Yili; Crofford, Leslie J; Wohlreich, Madelaine; Detke, Michael J; Iyengar, Smriti; Goldstein, David J (2004. ) A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder.Arthritis and rheumatism, , 50 (9 ) ,2974-84 More Information

Arnold, Lesley M; Keck, Paul E; Collins, Jacqueline; Wilson, Rodgers; Fleck, David E; Corey, Kimberly B; Amicone, Jennifer; Adebimpe, Victor R; Strakowski, Stephen M (2004. ) Ethnicity and first-rank symptoms in patients with psychosis.Schizophrenia research, , 67 (2-3 ) ,207-12 More Information

Arnold, Lesley M; Hudson, James I; Hess, Evelyn V; Ware, Avis E; Fritz, Deborah A; Auchenbach, Megan B; Starck, Linsey O; Keck, Paul E (2004. ) Family study of fibromyalgia.Arthritis and rheumatism, , 50 (3 ) ,944-52 More Information

Arnold, Lesley M; Strakowski, Stephen M; Schwiers, Michael L; Amicone, Jennifer; Fleck, David E; Corey, Kimberly B; Farrow, Jenni E (2004. ) Sex, ethnicity, and antipsychotic medication use in patients with psychosis.Schizophrenia research, , 66 (2-3 ) ,169-75 More Information

Arnold, Lesley M (2003. ) Gender differences in bipolar disorder. The Psychiatric clinics of North America, , 26 (3 ) ,595-620

Strakowski, Stephen M; Keck, Paul E; Arnold, Lesley M; Collins, Jacqueline; Wilson, Rodgers M; Fleck, David E; Corey, Kimberly B; Amicone, Jennifer; Adebimpe, Victor R (2003. ) Ethnicity and diagnosis in patients with affective disorders. The Journal of clinical psychiatry, , 64 (7 ) ,747-54

McElroy, Susan L; Arnold, Lesley M; Shapira, Nathan A; Keck, Paul E; Rosenthal, Norman R; Karim, M Rezaul; Kamin, Marc; Hudson, James I (2003. ) Topiramate in the treatment of binge eating disorder associated with obesity: a randomized, placebo-controlled trial. The American journal of psychiatry, , 160 (2 ) ,255-61

Arnold, Lesley M; McElroy, Susan L; Hudson, James I; Welge, Jeffrey A; Bennett, Aurora J; Keck, Paul E (2002. ) A placebo-controlled, randomized trial of fluoxetine in the treatment of binge-eating disorder. The Journal of clinical psychiatry, , 63 (11 ) ,1028-33

Arnold, Lesley M (2002. ) Phenomenology and therapeutic options for dermatotillomania.Expert review of neurotherapeutics, , 2 (5 ) ,725-30 More Information

Arnold, Lesley M; Hess, Evelyn V; Hudson, James I; Welge, Jeffrey A; Berno, Sarah E; Keck, Paul E (2002. ) A randomized, placebo-controlled, double-blind, flexible-dose study of fluoxetine in the treatment of women with fibromyalgia. The American journal of medicine, , 112 (3 ) ,191-7

Arnold, Lesley M. (1999. ) A Case Series of Women With Postpartum-Onset Obsessive-Compulsive Disorder. Primary care companion to the Journal of clinical psychiatry, , 1 (4 ) ,103-108

Ailani, Jessica; Lipton, Richard B; Goadsby, Peter J; Guo, Hua; Miceli, Rosa; Severt, Lawrence; Finnegan, Michelle; Trugman, Joel M (2021. ) Atogepant for the Preventive Treatment of Migraine.The New England journal of medicine, , 385 (8 ) ,695-706 More Information

Kleykamp, Bethea A; Ferguson, McKenzie C; McNicol, Ewan; Bixho, Ida; Arnold, Lesley M; Edwards, Robert R; Fillingim, Roger; Grol-Prokopczyk, Hanna; Turk, Dennis C; Dworkin, Robert H (2021. ) The Prevalence of Psychiatric and Chronic Pain Comorbidities in Fibromyalgia: an ACTTION systematic review.Seminars in arthritis and rheumatism, , 51 (1 ) ,166-174 More Information

Arnold, Lesley M; Whitaker, Susan; Hsu, Ching; Jacobs, David; Merante, Domenico (2019. ) Efficacy and safety of mirogabalin for the treatment of fibromyalgia: results from three 13-week randomized, double-blind, placebo- and active-controlled, parallel-group studies and a 52-week open-label extension study.Current medical research and opinion, , 35 (10 ) ,1825-1835 More Information

Arnold, Lesley M; Bennett, Robert M; Crofford, Leslie J; Dean, Linda E; Clauw, Daniel J; Goldenberg, Don L; Fitzcharles, Mary-Ann; Paiva, Eduardo S; Staud, Roland; Sarzi-Puttini, Piercarlo; Buskila, Dan; Macfarlane, Gary J (2019. ) Response to Wolfe. Letter to the Editor, "Fibromyalgia Criteria".The journal of pain, , 20 (6 ) ,741-742 More Information

Arnold, Lesley M; Bennett, Robert M; Crofford, Leslie J; Dean, Linda E; Clauw, Daniel J; Goldenberg, Don L; Fitzcharles, Mary-Ann; Paiva, Eduardo S; Staud, Roland; Sarzi-Puttini, Piercarlo; Buskila, Dan; Macfarlane, Gary J (2019. ) AAPT Diagnostic Criteria for Fibromyalgia.The journal of pain, , 20 (6 ) ,611-628 More Information

Upadhyaya, Himanshu P; Arnold, Lesley M; Alaka, Karla; Qiao, Meihua; Williams, David; Mehta, Renata (2019. ) Efficacy and safety of duloxetine versus placebo in adolescents with juvenile fibromyalgia: results from a randomized controlled trial.Pediatric rheumatology online journal, , 17 (1 ) ,27 More Information

Kashikar-Zuck, Susmita; Cunningham, Natoshia; Peugh, James; Black, William R; Nelson, Sarah; Lynch-Jordan, Anne M; Pfeiffer, Megan; Tran, Susan T; Ting, Tracy V; Arnold, Lesley M; Carle, Adam; Noll, Jennie; Powers, Scott W; Lovell, Daniel J (2019. ) Long-term outcomes of adolescents with juvenile-onset fibromyalgia into adulthood and impact of depressive symptoms on functioning over time.Pain, , 160 (2 ) ,433-441 More Information

Arnold, Lesley M; Choy, Ernest; Clauw, Daniel J; Oka, Hiroshi; Whalen, Ed; Semel, David; Pauer, Lynne; Knapp, Lloyd (2018. ) An evidence-based review of pregabalin for the treatment of fibromyalgia.Current medical research and opinion, , 34 (8 ) ,1397-1409 More Information

Dean, Linda E; Arnold, Lesley; Crofford, Leslie; Bennett, Robert; Goldenberg, Don; Fitzcharles, Mary-Ann; Paiva, Eduardo S; Staud, Roland; Clauw, Dan; Sarzi-Puttini, Piercarlo; Jones, Gareth T; Ayorinde, Abimbola; Flüß, Elisa; Beasley, Marcus; Macfarlane, Gary J (2017. ) Impact of Moving From a Widespread to Multisite Pain Definition on Other Fibromyalgia Symptoms.Arthritis care & research, , 69 (12 ) ,1878-1886 More Information

Arnold, Lesley M; McCarberg, Bill H; Clair, Andrew G; Whalen, Ed; Thomas, Neal; Jorga, Anamaria; Pauer, Lynne; Vissing, Richard; Park, Peter W (2017. ) Dose-response of pregabalin for diabetic peripheral neuropathy, postherpetic neuralgia, and fibromyalgia.Postgraduate medicine, , 129 (8 ) ,921-933 More Information

Arnold, Lesley M; Clauw, Daniel J (2017. ) Challenges of implementing fibromyalgia treatment guidelines in current clinical practice.Postgraduate medicine, , 129 (7 ) ,709-714 More Information

Arnold, Lesley M; Arsenault, Pierre; Huffman, Cynthia; Patrick, Jeffrey; Messig, Michael; Chew, Marci; Sanin, Luis; Scavone, Joseph; Pauer, Lynne; Clair, Andrew (2017. ) Corrections to: Once-daily controlled-release pregabalin in the treatment of patients with fibromyalgia: a phase III, double-blind, randomized withdrawal, placebo-controlled study.Current medical research and opinion, , 33 (4 ) ,795-796 More Information

Arnold, Lesley M; Choy, Ernest; Clauw, Daniel J; Goldenberg, Don L; Harris, Richard E; Helfenstein, Milton; Jensen, Troels Staehelin; Noguchi, Koichi; Silverman, Stuart L; Ushida, Takahiro; Wang, Guochun (2016. ) Fibromyalgia and Chronic Pain Syndromes: A White Paper Detailing Current Challenges in the Field.The Clinical journal of pain, , 32 (9 ) ,737-46 More Information

Arnold, Lesley M; Schikler, Kenneth N; Bateman, Lucinda; Khan, Tahira; Pauer, Lynne; Bhadra-Brown, Pritha; Clair, Andrew; Chew, Marci L; Scavone, Joseph (2016. ) Safety and efficacy of pregabalin in adolescents with fibromyalgia: a randomized, double-blind, placebo-controlled trial and a 6-month open-label extension study.Pediatric rheumatology online journal, , 14 (1 ) ,46 More Information

Kashikar-Zuck, Susmita; King, Christopher; Ting, Tracy V; Arnold, Lesley M (2016. ) Juvenile Fibromyalgia: Different from the Adult Chronic Pain Syndrome?.Current rheumatology reports, , 18 (4 ) ,19 More Information

Cunningham, Natoshia Raishevich; Tran, Susan T; Lynch-Jordan, Anne M; Ting, Tracy V; Sil, Soumitri; Strotman, Daniel; Noll, Jennie G; Powers, Scott W; Arnold, Lesley M; Kashikar-Zuck, Susmita (2015. ) Psychiatric Disorders in Young Adults Diagnosed with Juvenile Fibromyalgia in Adolescence.The Journal of rheumatology, , 42 (12 ) ,2427-33 More Information

Arnold, Lesley M; Sarzi-Puttini, Piercarlo; Arsenault, Pierre; Khan, Tahira; Bhadra Brown, Pritha; Clair, Andrew; Scavone, Joseph M; Driscoll, Joseph; Landen, Jaren; Pauer, Lynne (2015. ) Efficacy and Safety of Pregabalin in Patients with Fibromyalgia and Comorbid Depression Taking Concurrent Antidepressant Medication: A Randomized, Placebo-controlled Study.The Journal of rheumatology, , 42 (7 ) ,1237-44 More Information

Arnold, Lesley M; Bateman, Lucinda; Palmer, Robert H; Lin, Yuhua (2015. ) Preliminary experience using milnacipran in patients with juvenile fibromyalgia: lessons from a clinical trial program.Pediatric rheumatology online journal, , 13 ,27 More Information

Arnold, Lesley M; Blom, Thomas J; Welge, Jeffrey A; Mariutto, Elizabeth; Heller, Alicia A randomized, placebo-controlled, double-blinded trial of duloxetine in the treatment of general fatigue in patients with chronic fatigue syndrome.Psychosomatics, , 56 (3 ) ,242-53 More Information

Arnold, Lesley M; Emir, Birol; Pauer, Lynne; Resnick, Malca; Clair, Andrew (2015. ) Time to improvement of pain and sleep quality in clinical trials of pregabalin for the treatment of fibromyalgia.Pain medicine (Malden, Mass.), , 16 (1 ) ,176-85 More Information

Arnold, Lesley M; Arsenault, Pierre; Huffman, Cynthia; Patrick, Jeffrey L; Messig, Michael; Chew, Marci L; Sanin, Luis; Scavone, Joseph M; Pauer, Lynne; Clair, Andrew G (2014. ) Once daily controlled-release pregabalin in the treatment of patients with fibromyalgia: a phase III, double-blind, randomized withdrawal, placebo-controlled study.Current medical research and opinion, , 30 (10 ) ,2069-83 More Information

Kleinman, Leah; Mannix, Sally; Arnold, Lesley M; Burbridge, Claire; Howard, Kellee; McQuarrie, Kelly; Pitman, Verne; Resnick, Malca; Roth, Tom; Symonds, Tara (2014. ) Assessment of sleep in patients with fibromyalgia: qualitative development of the fibromyalgia sleep diary.Health and quality of life outcomes, , 12 ,111 More Information

Sil, Soumitri; Arnold, Lesley M; Lynch-Jordan, Anne; Ting, Tracy V; Peugh, James; Cunningham, Natoshia; Powers, Scott W; Lovell, Daniel J; Hashkes, Philip J; Passo, Murray; Schikler, Kenneth N; Kashikar-Zuck, Susmita (2014. ) Identifying treatment responders and predictors of improvement after cognitive-behavioral therapy for juvenile fibromyalgia.Pain, , 155 (7 ) ,1206-1212 More Information

Roth, Thomas; Arnold, Lesley M; Garcia-Borreguero, Diego; Resnick, Malca; Clair, Andrew G (2014. ) A review of the effects of pregabalin on sleep disturbance across multiple clinical conditions.Sleep medicine reviews, , 18 (3 ) ,261-71 More Information

Martin, Susan A; Coon, Cheryl D; McLeod, Lori D; Chandran, Arthi; Arnold, Lesley M (2014. ) Evaluation of the fibromyalgia diagnostic screen in clinical practice.Journal of evaluation in clinical practice, , 20 (2 ) ,158-65 More Information

Fillingim, Roger B; Bruehl, Stephen; Dworkin, Robert H; Dworkin, Samuel F; Loeser, John D; Turk, Dennis C; Widerstrom-Noga, Eva; Arnold, Lesley; Bennett, Robert; Edwards, Robert R; Freeman, Roy; Gewandter, Jennifer; Hertz, Sharon; Hochberg, Marc; Krane, Elliot; Mantyh, Patrick W; Markman, John; Neogi, Tuhina; Ohrbach, Richard; Paice, Judith A; Porreca, Frank; Rappaport, Bob A; Smith, Shannon M; Smith, Thomas J; Sullivan, Mark D; Verne, G Nicholas; Wasan, Ajay D; Wesselmann, Ursula (2014. ) The ACTTION-American Pain Society Pain Taxonomy (AAPT): an evidence-based and multidimensional approach to classifying chronic pain conditions.The journal of pain, , 15 (3 ) ,241-9 More Information

Kashikar-Zuck, Susmita; Cunningham, Natoshia; Sil, Soumitri; Bromberg, Maggie H; Lynch-Jordan, Anne M; Strotman, Daniel; Peugh, James; Noll, Jennie; Ting, Tracy V; Powers, Scott W; Lovell, Daniel J; Arnold, Lesley M (2014. ) Long-term outcomes of adolescents with juvenile-onset fibromyalgia in early adulthood.Pediatrics, , 133 (3 ) ,e592-600 More Information

Arnold, Lesley M; Palmer, Robert H; Ma, Yimin (2013. ) A 3-year, open-label, flexible-dosing study of milnacipran for the treatment of fibromyalgia.The Clinical journal of pain, , 29 (12 ) ,1021-8 More Information

Joffe, Naomi E; Lynch-Jordan, Anne; Ting, Tracy V; Arnold, Lesley M; Hashkes, Philip J; Lovell, Daniel J; Passo, Murray H; Powers, Scott W; Schikler, Kenneth N; Kashikar-Zuck, Susmita (2013. ) Utility of the PedsQL rheumatology module as an outcome measure in juvenile fibromyalgia.Arthritis care & research, , 65 (11 ) ,1820-7 More Information

Wells, Alvin F; Arnold, Lesley M; Curtis, Cassandra E; Dunegan, L Jean; Lapp, Charles W; McCarberg, Bill H; Clair, Andrew (2013. ) Integrating health information technology and electronic health records into the management of fibromyalgia.Postgraduate medicine, , 125 (4 ) ,70-7 More Information

Arnold, Lesley M; Cappelleri, Joseph C; Clair, Andrew; Masters, Elizabeth T (2013. ) Interpreting effect sizes and clinical relevance of pharmacological interventions for fibromyalgia.Pain and therapy, , 2 (1 ) ,65-71 More Information

Kashikar-Zuck, Susmita; Sil, Soumitri; Lynch-Jordan, Anne M; Ting, Tracy V; Peugh, James; Schikler, Kenneth N; Hashkes, Philip J; Arnold, Lesley M; Passo, Murray; Richards-Mauze, Margaret M; Powers, Scott W; Lovell, Daniel J (2013. ) Changes in pain coping, catastrophizing, and coping efficacy after cognitive-behavioral therapy in children and adolescents with juvenile fibromyalgia.The journal of pain, , 14 (5 ) ,492-501 More Information

Arnold, Lesley M; Fan, Jinbo; Russell, I Jon; Yunus, Muhammad B; Khan, Muhammad Asim; Kushner, Irving; Olson, Jane M; Iyengar, Sudha K (2013. ) The fibromyalgia family study: a genome-wide linkage scan study.Arthritis and rheumatism, , 65 (4 ) ,1122-8 More Information

Arnold, Lesley M; Zhang, Shuyu; Pangallo, Beth A Efficacy and safety of duloxetine 30 mg/d in patients with fibromyalgia: a randomized, double-blind, placebo-controlled study.The Clinical journal of pain, , 28 (9 ) ,775-81 More Information

Chandran, Arthi B; Coon, Cheryl D; Martin, Susan A; McLeod, Lori D; Coles, Theresa M; Arnold, Lesley M Sphygmomanometry-evoked allodynia in chronic pain patients with and without fibromyalgia.Nursing research, , 61 (5 ) ,363-8 More Information

Arnold, Lesley M; Hirsch, Ian; Sanders, Paul; Ellis, Amanda; Hughes, Bernadette (2012. ) Safety and efficacy of esreboxetine in patients with fibromyalgia: a fourteen-week, randomized, double-blind, placebo-controlled, multicenter clinical trial.Arthritis and rheumatism, , 64 (7 ) ,2387-97 More Information

Mohs, Richard; Mease, Philip; Arnold, Lesley M; Wang, Fujun; Ahl, Jonna; Gaynor, Paula J; Wohlreich, Madelaine M The effect of duloxetine treatment on cognition in patients with fibromyalgia.Psychosomatic medicine, , 74 (6 ) ,628-34 More Information

Arnold, Lesley M; Palmer, Robert H; Gendreau, R Michael; Chen, Wei Relationships among pain, depressed mood, and global status in fibromyalgia patients: post hoc analyses of a randomized, placebo-controlled trial of milnacipran.Psychosomatics, , 53 (4 ) ,371-9 More Information

Gara, Michael A; Vega, William A; Arndt, Stephan; Escamilla, Michael; Fleck, David E; Lawson, William B; Lesser, Ira; Neighbors, Harold W; Wilson, Daniel R; Arnold, Lesley M; Strakowski, Stephen M (2012. ) Influence of patient race and ethnicity on clinical assessment in patients with affective disorders.Archives of general psychiatry, , 69 (6 ) ,593-600 More Information

Arnold, Lesley M; Emir, Birol; Murphy, T Kevin; Zeiher, Bernhardt G; Pauer, Lynne; Scott, Gayle; Petersel, Danielle (2012. ) Safety profile and tolerability of up to 1 year of pregabalin treatment in 3 open-label extension studies in patients with fibromyalgia.Clinical therapeutics, , 34 (5 ) ,1092-102 More Information

Saxe, Philippe A; Arnold, Lesley M; Palmer, Robert H; Gendreau, R Michael; Chen, Wei (2012. ) Short-term (2-week) effects of discontinuing milnacipran in patients with fibromyalgia.Current medical research and opinion, , 28 (5 ) ,815-21 More Information

Arnold, Lesley M; Clauw, Daniel J; Dunegan, L Jean; Turk, Dennis C (2012. ) A framework for fibromyalgia management for primary care providers.Mayo Clinic proceedings, , 87 (5 ) ,488-96 More Information

Mariutto, Elizabeth N; Stanford, Sharon B; Kashikar-Zuck, Susmita; Welge, Jeffrey A; Arnold, Lesley M (2012. ) An exploratory, open trial of fluoxetine treatment of juvenile fibromyalgia.Journal of clinical psychopharmacology, , 32 (2 ) ,293-5 More Information

Arnold, Lesley M; Williams, David A; Hudson, James I; Martin, Susan A; Clauw, Daniel J; Crofford, Leslie J; Wang, Fujun; Emir, Birol; Lai, Chinglin; Zablocki, Rong; Mease, Philip J (2012. ) Development of responder definitions for fibromyalgia clinical trials.Arthritis and rheumatism, , 64 (3 ) ,885-94 More Information

Arnold, Lesley M; Stanford, Sharon B; Welge, Jeffrey A; Crofford, Leslie J (2012. ) Development and testing of the fibromyalgia diagnostic screen for primary care.Journal of women's health (2002), , 21 (2 ) ,231-9 More Information

Kashikar-Zuck, Susmita; Ting, Tracy V; Arnold, Lesley M; Bean, Judy; Powers, Scott W; Graham, T Brent; Passo, Murray H; Schikler, Kenneth N; Hashkes, Philip J; Spalding, Steven; Lynch-Jordan, Anne M; Banez, Gerard; Richards, Margaret M; Lovell, Daniel J (2012. ) Cognitive behavioral therapy for the treatment of juvenile fibromyalgia: a multisite, single-blind, randomized, controlled clinical trial.Arthritis and rheumatism, , 64 (1 ) ,297-305 More Information

Arnold, Lesley M; Palmer, Robert H; Hufford, Michael R; Chen, Wei (2012. ) Effect of milnacipran on body weight in patients with fibromyalgia.International journal of general medicine, , 5 ,879-87 More Information

Williams, David A; Arnold, Lesley M (2011. ) Measures of fibromyalgia: Fibromyalgia Impact Questionnaire (FIQ), Brief Pain Inventory (BPI), Multidimensional Fatigue Inventory (MFI-20), Medical Outcomes Study (MOS) Sleep Scale, and Multiple Ability Self-Report Questionnaire (MASQ).Arthritis care & research, , 63 Suppl 11 ,S86-97 More Information

Wang, Fujun; Ruberg, Stephen J; Gaynor, Paula J; Heinloth, Alexandra N; Arnold, Lesley M (2011. ) Early improvement in pain predicts pain response at endpoint in patients with fibromyalgia.The journal of pain, , 12 (10 ) ,1088-94 More Information

Clauw, Daniel J; Arnold, Lesley M; McCarberg, Bill H (2011. ) The science of fibromyalgia.Mayo Clinic proceedings, , 86 (9 ) ,907-11 More Information

Mease, Philip J; Clauw, Daniel J; Christensen, Robin; Crofford, Leslie J; Gendreau, R Michael; Martin, Susan A; Simon, Lee S; Strand, Vibeke; Williams, David A; Arnold, Lesley M (2011. ) Toward development of a fibromyalgia responder index and disease activity score: OMERACT module update.The Journal of rheumatology, , 38 (7 ) ,1487-95 More Information

Arnold, Lesley M; Wang, Fujun; Ahl, Jonna; Gaynor, Paula J; Wohlreich, Madelaine M (2011. ) Improvement in multiple dimensions of fatigue in patients with fibromyalgia treated with duloxetine: secondary analysis of a randomized, placebo-controlled trial.Arthritis research & therapy, , 13 (3 ) ,R86 More Information

Mease, Philip J; Spaeth, Michael; Clauw, Daniel J; Arnold, Lesley M; Bradley, Laurence A; Russell, I Jon; Kajdasz, Daniel K; Walker, Daniel J; Chappell, Amy S (2011. ) Estimation of minimum clinically important difference for pain in fibromyalgia.Arthritis care & research, , 63 (6 ) ,821-6 More Information

Arnold, Lesley M; Clauw, Daniel J; McCarberg, Bill H (2011. ) Improving the recognition and diagnosis of fibromyalgia.Mayo Clinic proceedings, , 86 (5 ) ,457-64 More Information

Arnold, Lesley M; Zlateva, Gergana; Sadosky, Alesia; Emir, Birol; Whalen, Ed (2011. ) Correlations between fibromyalgia symptom and function domains and patient global impression of change: a pooled analysis of three randomized, placebo-controlled trials of pregabalin.Pain medicine (Malden, Mass.), , 12 (2 ) ,260-7 More Information

Arnold, Lesley M; Leon, Teresa; Whalen, Ed; Barrett, Jeannette Relationships among pain and depressive and anxiety symptoms in clinical trials of pregabalin in fibromyalgia.Psychosomatics, , 51 (6 ) ,489-97 More Information

Arnold, Lesley M; Chatamra, Krai; Hirsch, Ian; Stoker, Malcolm (2010. ) Safety and efficacy of esreboxetine in patients with fibromyalgia: An 8-week, multicenter, randomized, double-blind, placebo-controlled study.Clinical therapeutics, , 32 (9 ) ,1618-32 More Information

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer (2007. ) Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania.Archives of general psychiatry, , 64 (1 ) ,57-64 More Information

Strakowski, Stephen M; DelBello, Melissa P; Fleck, David E; Adler, Caleb M; Anthenelli, Robert M; Keck, Paul E; Arnold, Lesley M; Amicone, Jennifer (2005. ) Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania.Archives of general psychiatry, , 62 (8 ) ,851-8 More Information

Other Information

Lesley Arnold, MD, is a doctor with University of Cincinnati Physicians.

Practice Location:
UC Health Psychiatry (Stetson Building)
260 Stetson Street
Suite 3200
Cincinnati, OH 45219

Clinical Specialties:
Psychiatry/Psychology, Fibromyalgia, Chronic Fatigue Syndrome, Depression, Women's Health Research Program

To make an appointment, please call (513) 475-8000.

 

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Contact Information

Academic - Stetson Building
Suite 3200
Cincinnati  Ohio, 45219
Phone: 513-558-7700
lesley.arnold@uc.edu