George Babcock

George F. Babcock , PhD


Shriners Hospitals for Children - Cincinnati
Room 446
3229 Burnet Avenue
Cincinnati, Ohio 45229
Phone 513-872-6231


Bachelor's Degree: Muskingum College 1970 (Biology)

Master's Degree: North Dakota State University 1972

Doctoral Degree: University of Nebraska Medical Center 1975 (Medical Microbiology and Immunology)

Postdoctoral Training: University of North Carolina 1978 (Microbiology and Immunology)

Research and Practice Interests

Immunology of Burns, Trauma and Infectious Disease

Research Support

Grant: #SRS 002562 Investigators:Babcock, George 03-19-2007 -03-19-2012 Naval Health Research Center Navy Education Partnership Role:PI $.00 Active Level:Federal

Investigators:Babcock, George 08-01-2003 -07-31-2005 Thrasher Research Fund The Reduction of Infections in Seriously Burned Patients Role:PI $174,836.00 Closed Level:Private Non-Profit

Grant: #07-W911QY-08-P-0469 Investigators:Babcock, George 07-17-2008 -07-16-2009 Naval Health Research Center the Short and Long Term Immunological Response and Long Term Genotoxic Effects of Using Tungsten in Military Munitions Role:PI $80,393.00 Closed Level:Federal

Grant: #W911QY-08-P-0779 Investigators:Babcock, George 09-19-2008 -12-31-2009 Department of the Navy The Effects of Ingestion of Iraqi Particulate Matter on the Intestine and Immune System Role:PI $83,790.00 Closed Level:Federal

Grant: #1006754 Investigators:Babcock, George; Dugan, Amy; Horseman, Nelson 01-01-2009 -12-31-2009 Shriners Hospitals for Children - Cincinnati Shrine Physiology 2009 Consulting Agreements Role:Collaborator $175,036.00 Closed Level:Private Non-Profit

Grant: #W911QY-09-P-0706 Investigators:Babcock, George 09-29-2009 -09-28-2010 Office of Naval Research Effects of Environmental Toxins For Burn Injuries and Severe Trauma Role:PI $80,000.00 Active Level:Federal

Grant: #W911QY-10-C-0103 Investigators:Babcock, George 05-03-2010 -11-30-2011 Naval Health Research Center The Effects of Short-Term Exposure to Tungsten on the Immune Response Role:PI $159,963.00 Closed Level:Federal

Grant: #R21 EY021768 Investigators:Babcock, George; Kao, Winston Whei Yang; Liu, Hongshan 09-30-2011 -08-31-2015 National Eye Institute Cell Therapy of Corneal Diseases with Umbilical Mesenchyme Stem Cells Role:Collaborator $1,705,844.00 Active Level:Federal

Grant: #Prime W81XWH-11-2-0233-P00001 Investigators:Babcock, George; Healy, Daniel 09-30-2011 -03-30-2013 Department of the Army Medical Research Acquisition Activity The use of TheraGauze in the Treatment of Burn Wounds Role:PI $163,595.00 Active Level:Federal

Grant: #Prime W81XWH-11-2-0233-P00001 Investigators:Babcock, George; Healy, Daniel 09-30-2011 -03-30-2013 Department of the Army Medical Research Acquisition Activity The use of TheraGauze in the Treatment of Burn Wounds Role:PI $163,595.00 Closed Level:Federal

Grant: #LP- NCRADA-NMRC-15-9713 Investigators:Babcock, George 03-17-2016 -03-16-2017 Department of the Navy A Limited Purpose Coorperative Research and Development Agreement For Material Transfer Role:PI $.00 Active Level:Federal

Grant: #DoD1-SA1 / W81XWH-15-2-0065 Investigators:Babcock, George; Lentsch, Alex 01-01-2017 -12-31-2017 Department of the Army Medical Research Acquisition Activity Antimicrobial block copolypeptides (A-Blocks): Innovative Therapeutics and Prophylacics for Wound Infection Role:PI $517,802.00 Awarded Level:Federal

Grant: #AMIC-AW1 Investigators:Babcock, George 07-01-2018 -12-31-2018 Amicrobe, Inc. Antimicrobial block copolypeptides (A-Blocks): Innovative Therapeutics and Prophylacics for Wound Infection Role:PI $130,000.00 Active Level:Industry

Grant: #2019 Research Agreement Investigators:Babcock, George 01-01-2019 -03-31-2019 Rem Brands, Inc. Efficacy Study of a Test Compound in a Murine Infection Model Role:PI $45,496.00 Active Level:Industry


Peer Reviewed Publications

Osterburg, Andrew R; Hexley, Philip; Supp, Dorothy M; Robinson, Chad T; Noel, Greg; Ogle, Cora; Boyce, Steven T; Aronow, Bruce J; Babcock, George F (2013. ) Concerns over interspecies transcriptional comparisons in mice and humans after trauma.Proceedings of the National Academy of Sciences of the United States of America, , 110 (36 ) ,E3370 More Information

Swope, Viki B; Jameson, Joshua A; McFarland, Kevin L; Supp, Dorothy M; Miller, William E; McGraw, Dennis W; Patel, Mira A; Nix, Matthew A; Millhauser, Glenn L; Babcock, George F; Abdel-Malek, Zalfa A (2012. ) Defining MC1R regulation in human melanocytes by its agonist ?-melanocortin and antagonists agouti signaling protein and ?-defensin 3.The Journal of investigative dermatology, , 132 (9 ) ,2255-62 More Information

Tichy, Elisia D; Pillai, Resmi; Deng, Li; Tischfield, Jay A; Hexley, Philip; Babcock, George F; Stambrook, Peter J (2012. ) The abundance of Rad51 protein in mouse embryonic stem cells is regulated at multiple levels.Stem cell research, , 9 (2 ) ,124-34 More Information

Hexley, Philip; Robinson, Chad T; Osterburg, Andrew R; Babcock, George F (2012. ) Circulating microparticles do not all share biophysical light scatter properties with immune complexes when analyzed by flow cytometry.Blood, , 120 (7 ) ,1528-9 More Information

Babcock, George F; Hernandez, Laura; Yadav, Ekta; Schwemberger, Sandy; Dugan, Amy (2012. ) The burn wound inflammatory response is influenced by midazolam.Inflammation, , 35 (1 ) ,259-70 More Information

Kavanaugh, Gina M; Wise-Draper, Trisha M; Morreale, Richard J; Morrison, Monique A; Gole, Boris; Schwemberger, Sandy; Tichy, Elisia D; Lu, Lu; Babcock, George F; Wells, James M; Drissi, Rachid; Bissler, John J; Stambrook, Peter J; Andreassen, Paul R; Wiesmüller, Lisa; Wells, Susanne I (2011. ) The human DEK oncogene regulates DNA damage response signaling and repair.Nucleic acids research, , 39 (17 ) ,7465-76 More Information

Tichy, Elisia D; Pillai, Resmi; Deng, Li; Liang, Li; Tischfield, Jay; Schwemberger, Sandy J; Babcock, George F; Stambrook, Peter J (2010. ) Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks.Stem cells and development, , 19 (11 ) ,1699-711 More Information

Jacobson, Eric M; Yang, Heyi; Menconi, Francesca; Wang, Rong; Osman, Roman; Skrabanek, Luce; Li, Cheuk Wun; Fadlalla, Mohammed; Gandhi, Alisha; Chaturvedi, Vijaya; Smith, Eric P; Schwemberger, Sandy; Osterburg, Andrew; Babcock, George F; Tomer, Yaron (2009. ) Employing a recombinant HLA-DR3 expression system to dissect major histocompatibility complex II-thyroglobulin peptide dynamism: a genetic, biochemical, and reverse immunological perspective.The Journal of biological chemistry, , 284 (49 ) ,34231-43 More Information

Bommireddy, R; Bueno, O F; Martin, J; Ormsby, I; Chen, H; Gard, C; Molkentin, J D; Boivin, G P; Babcock, G F; Doetschman, T (2009. ) Calcineurin deficiency decreases inflammatory lesions in transforming growth factor beta1-deficient mice.Clinical and experimental immunology, , 158 (3 ) ,317-24 More Information

Azhar, Mohamad; Yin, Moying; Bommireddy, Ramireddy; Duffy, John J; Yang, Junqi; Pawlowski, Sharon A; Boivin, Gregory P; Engle, Sandra J; Sanford, L P; Grisham, Christina; Singh, Ram R; Babcock, George F; Doetschman, Thomas (2009. ) Generation of mice with a conditional allele for transforming growth factor beta 1 gene.Genesis (New York, N.Y. : 2000), , 47 (6 ) ,423-31 More Information

Fumagalli, Stefano; Di Cara, Alessandro; Neb-Gulati, Arti; Natt, Francois; Schwemberger, Sandy; Hall, Jonathan; Babcock, George F; Bernardi, Rosa; Pandolfi, Pier Paolo; Thomas, George (2009. ) Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction.Nature cell biology, , 11 (4 ) ,501-8 More Information

Bommireddy, Ramireddy; Babcock, George F; Singh, Ram R; Doetschman, Thomas (2008. ) TGFbeta1 deficiency does not affect the generation and maintenance of CD4+CD25+FOXP3+ putative Treg cells, but causes their numerical inadequacy and loss of regulatory function.Clinical immunology (Orlando, Fla.), , 127 (2 ) ,206-13 More Information

Caldwell, Julie M; Chen, Yinhuai; Schollaert, Kaila L; Theis, James F; Babcock, George F; Newlon, Carol S; Sanchez, Yolanda (2008. ) Orchestration of the S-phase and DNA damage checkpoint pathways by replication forks from early origins.The Journal of cell biology, , 180 (6 ) ,1073-86 More Information

Markey, M P; Bergseid, J; Bosco, E E; Stengel, K; Xu, H; Mayhew, C N; Schwemberger, S J; Braden, W A; Jiang, Y; Babcock, G F; Jegga, A G; Aronow, B J; Reed, M F; Wang, J Y J; Knudsen, E S (2007. ) Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune function.Oncogene, , 26 (43 ) ,6307-18 More Information

Dugan, Amy L; Schwemberger, Sandy; Noel, Greg J; Babcock, George F; Ogle, Cora K; Buckley, Donna J; Horseman, Nelson D; Gregerson, Karen A (2007. ) Stress and prolactin effects on bone marrow myeloid cells, serum chemokine and serum glucocorticoid levels in mice.Neuroimmunomodulation, , 14 (6 ) ,287-96 More Information

Wetherill, Yelena B; Hess-Wilson, Janet K; Comstock, Clay E S; Shah, Supriya A; Buncher, C Ralph; Sallans, Larry; Limbach, Patrick A; Schwemberger, Sandy; Babcock, George F; Knudsen, Karen E (2006. ) Bisphenol A facilitates bypass of androgen ablation therapy in prostate cancer.Molecular cancer therapeutics, , 5 (12 ) ,3181-90 More Information

Bommireddy, Ramireddy; Pathak, Leena J; Martin, Jennifer; Ormsby, Ilona; Engle, Sandra J; Boivin, Gregory P; Babcock, George F; Eriksson, Anna U; Singh, Ram R; Doetschman, Thomas (2006. ) Self-antigen recognition by TGF beta1-deficient T cells causes their activation and systemic inflammation.Laboratory investigation; a journal of technical methods and pathology, , 86 (10 ) ,1008-19 More Information

Mayhew, Christopher N; Bosco, Emily E; Fox, Sejal R; Okaya, Tomohisa; Tarapore, Pheruza; Schwemberger, Sandy J; Babcock, George F; Lentsch, Alex B; Fukasawa, Kenji; Knudsen, Erik S (2005. ) Liver-specific pRB loss results in ectopic cell cycle entry and aberrant ploidy.Cancer research, , 65 (11 ) ,4568-77 More Information

Keshavan, Pavitra; Deem, Tracy L; Schwemberger, Sandy J; Babcock, George F; Cook-Mills, Joan M; Zucker, Stephen D (2005. ) Unconjugated bilirubin inhibits VCAM-1-mediated transendothelial leukocyte migration. Journal of immunology (Baltimore, Md. : 1950), , 174 (6 ) ,3709-18

Keshavan, Pavitra; Schwemberger, Sandy J; Smith, Darcey L H; Babcock, George F; Zucker, Stephen D (2004. ) Unconjugated bilirubin induces apoptosis in colon cancer cells by triggering mitochondrial depolarization.International journal of cancer, , 112 (3 ) ,433-45 More Information

Babcock, George F (2004. ) Common problems encountered by IACUCs--one chair's perspective. Contemporary topics in laboratory animal science, , 43 (3 ) ,70-1

Babcock, George F (2004. ) Intracellular cytokines.Current protocols in cytometry, , Chapter 9 ,Unit 9.9 More Information

Dugan, Amy L; Schwemberger, Sandy; Babcock, George F; Buckley, Donna; Buckley, Arthur R; Ogle, Cora K; Horseman, Nelson D (2004. ) Effects of prolactin level on burn-induced aberrations in myelopoiesis.Shock (Augusta, Ga.), , 21 (2 ) ,151-9 More Information

Babcock, George F (2003. ) Predictive medicine: severe trauma and burns.Cytometry. Part B, Clinical cytometry, , 53 (1 ) ,48-53 More Information

Bommireddy, Ramireddy; Saxena, Vijay; Ormsby, Ilona; Yin, Moying; Boivin, Gregory P; Babcock, George F; Singh, Ram R; Doetschman, Thomas (2003. ) TGF-beta 1 regulates lymphocyte homeostasis by preventing activation and subsequent apoptosis of peripheral lymphocytes. Journal of immunology (Baltimore, Md. : 1950), , 170 (9 ) ,4612-22

Bommireddy, Ramireddy; Ormsby, Ilona; Yin, Moying; Boivin, Gregory P; Babcock, George F; Doetschman, Thomas (2003. ) TGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytes. Journal of immunology (Baltimore, Md. : 1950), , 170 (7 ) ,3645-52

Heinen, Christopher D; Goss, Kathleen Heppner; Cornelius, James R; Babcock, George F; Knudsen, Erik S; Kowalik, Timothy; Groden, Joanna (2002. ) The APC tumor suppressor controls entry into S-phase through its ability to regulate the cyclin D/RB pathway. Gastroenterology, , 123 (3 ) ,751-63

Gibson, S W; Valente, J F; Alexander, J W; Custer, D A; Li, B G; Frede, S; Babcock, G F; Ogle, C K (2000. ) Nutritional immunomodulation leads to enhanced allograft survival in combination with cyclosporine A and rapamycin, but not FK506. Transplantation, , 69 (10 ) ,2034-8

Le Poole, I C; Yang, F; Brown, T L; Cornelius, J; Babcock, G F; Das, P K; Boissy, R E (1999. ) Altered gene expression in melanocytes exposed to 4-tertiary butyl phenol (4-TBP): upregulation of the A2b adenosine receptor 1.The Journal of investigative dermatology, , 113 (5 ) ,725-31 More Information

Rodeberg, D A; Meyer, J G; Babcock, G F (1999. ) Heat shock response: presence and effects in burn patient neutrophils. Journal of leukocyte biology, , 66 (5 ) ,773-80

Jawa, R S; Quaid, G A; Williams, M A; Cave, C M; Robinson, C T; Babcock, G F; Lieberman, M A; Witt, D; Solomkin, J S (1999. ) Tumor necrosis factor alpha regulates CXC chemokine receptor expression and function. Shock (Augusta, Ga.), , 11 (6 ) ,385-90

Gibson, S W; Valente, J F; Alexander, J W; Custer, D A; Babcock, G F; Ogle, C K (1999. ) The effect of nutritional immunomodulation on cardiac allograft survival in rats receiving mycophenolate mofetil, cyclosporine A, and donor-specific transfusion. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, , 18 (3 ) ,185-9

Babcock, G F (1999. ) Quantitation of phagocytosis by confocal microscopy. Methods in enzymology, , 307 ,319-28

King, K L; Moreira, K M; Babcock, G F; Wang, J; Campos, B; Kaetzel, M A; Dedman, J R (1998. ) Temporal inhibition of calmodulin in the nucleus. Biochimica et biophysica acta, , 1448 (2 ) ,245-53

Alexander, J W; Valente, J F; Greenberg, N A; Custer, D A; Ogle, C K; Gibson, S W; Babcock, G F (1998. ) Dietary omega-3 and omega-9 fatty acids uniquely enhance allograft survival in cyclosporine-treated and donor-specific transfusion-treated rats. Transplantation, , 65 (10 ) ,1304-9

Rodeberg, D A; Morris, R E; Babcock, G F (1997. ) Azurophilic granules of human neutrophils contain CD14. Infection and immunity, , 65 (11 ) ,4747-53

Swope, V B; Supp, A P; Cornelius, J R; Babcock, G F; Boyce, S T (1997. ) Regulation of pigmentation in cultured skin substitutes by cytometric sorting of melanocytes and keratinocytes. The Journal of investigative dermatology, , 109 (3 ) ,289-95

Levy, A E; Alexander, J W; Babcock, G F (1997. ) A strategy for generating consistent long-term donor-specific tolerance to solid organ allografts. Transplant immunology, , 5 (2 ) ,83-8

Rodeberg, D A; Bass, R C; Alexander, J W; Warden, G D; Babcock, G F (1997. ) Neutrophils from burn patients are unable to increase the expression of CD11b/CD18 in response to inflammatory stimuli. Journal of leukocyte biology, , 61 (5 ) ,575-82

Hess, K L; Babcock, G F; Askew, D S; Cook-Mills, J M (1997. ) A novel flow cytometric method for quantifying phagocytosis of apoptotic cells. Cytometry, , 27 (2 ) ,145-52

Goggins, W C; Fisher, R A; Dattilo, J B; Cohen, D S; Tawes, J W; Dattilo, M P; Babcock, G F; Frede, S E; Wakely, P E; Posner, M P (1997. ) Analysis of functional renal allograft tolerance with single-dose rapamycin based induction immunosuppression. Transplantation, , 63 (2 ) ,310-4

Frede, S E; Levy, A E; Alexander, J W; Babcock, G F (1996. ) An examination of tissue chimerism in the ACI to Lewis rat cardiac transplant model. Transplant immunology, , 4 (3 ) ,227-31

Gennari, R; Alexander, J W; Boyce, S T; Lilly, N; Babcock, G F; Cornaggia, M (1996. ) Effects of the angiotensin converting enzyme inhibitor enalapril on bacterial translocation after thermal injury and bacterial challenge. Shock (Augusta, Ga.), , 6 (2 ) ,95-100

Kane, T D; Johnson, S R; Alexander, J W; Babcock, G F; Ogle, C K (1996. ) Detection of intestinal bacterial translocation using PCR.The Journal of surgical research, , 63 (1 ) ,59-63 More Information

Babcock, G F; Alexander, J W (1996. ) The effects of blood transfusion on cytokine production by TH1 and TH2 lymphocytes in the mouse. Transplantation, , 61 (3 ) ,465-8

Peck, M D; Babcock, G F; Alexander, J W; Billiar, T; Ochoa, J (1995. ) High doses of dietary arginine during repletion impair weight gain and increase infectious mortality in protein-malnourished mice. The British journal of nutrition, , 74 (6 ) ,787-95

Gennari, R; Alexander, J W; Eaves-Pyles, T; Babcock, G F (1994. ) Heparan sulfate increases survival during gut-derived sepsis by decreasing bacterial translocation and enhancing host defense. Shock (Augusta, Ga.), , 2 (4 ) ,246-50

Swope, V B; Sauder, D N; McKenzie, R C; Sramkoski, R M; Krug, K A; Babcock, G F; Nordlund, J J; Abdel-Malek, Z A (1994. ) Synthesis of interleukin-1 alpha and beta by normal human melanocytes. The Journal of investigative dermatology, , 102 (5 ) ,749-53

Solomkin, J S; Bass, R C; Bjornson, H S; Tindal, C J; Babcock, G F (1994. ) Alterations of neutrophil responses to tumor necrosis factor alpha and interleukin-8 following human endotoxemia. Infection and immunity, , 62 (3 ) ,943-7

Babcock, G F; Dawes, S M (1994. ) Immunophenotyping using fixed cells. Methods in cell biology, , 41 ,81-93

De Stefano, J A; Foy, J M; Sullivan, D W; Dawes, S M; Cushion, M T; Babcock, G F; Sleight, R G; van Halbeek, H; Walzer, P D (1994. ) Fractionation of Pneumocystis carinii developmental stages by counterflow centrifugal elutriation and sequential filtrations. Parasitology research, , 80 (1 ) ,1-9

Gianotti, L; Munda, R; Alexander, J W; Tchervenkov, J I; Babcock, G F (1993. ) Bacterial translocation: a potential source for infection in acute pancreatitis. Pancreas, , 8 (5 ) ,551-8

Gianotti, L; Alexander, J W; Pyles, T; Fukushima, R; Babcock, G F (1993. ) Prostaglandin E1 analogues misoprostol and enisoprost decrease microbial translocation and modulate the immune response. Circulatory shock, , 40 (4 ) ,243-9

Wolos, J A; Frondorf, K A; Babcock, G F; Stripp, S A; Bowlin, T L (1993. ) Immunomodulation by an inhibitor of S-adenosyl-L-homocysteine hydrolase: inhibition of in vitro and in vivo allogeneic responses.Cellular immunology, , 149 (2 ) ,402-8 More Information

White-Owen, C; Hartmann, S; Alexander, J W; Babcock, G F (1993. ) Reduced PMN beta 2 integrins after trauma: a possible role for colony-stimulating factors. Clinical and experimental immunology, , 92 (3 ) ,477-81

Gianotti, L; Pyles, T; Alexander, J W; Fukushima, R; Babcock, G F (1993. ) Identification of the blood component responsible for increased susceptibility to gut-derived infection. Transfusion, , 33 (6 ) ,458-65

White-Owen, C; Alexander, J W; Sramkoski, R M; Babcock, G F (1992. ) Rapid whole-blood microassay using flow cytometry for measuring neutrophil phagocytosis. Journal of clinical microbiology, , 30 (8 ) ,2071-6

Gianotti, L; Pyles, T; Alexander, J W; Babcock, G F; Carey, M A (1992. ) Impact of blood transfusion and burn injury on microbial translocation and bacterial survival. Transfusion, , 32 (4 ) ,312-7

Alexander, J W; Babcock, G F; First, M R; Davies, C B; Madden, R L; Munda, R; Penn, I; Fidler, J P; Cofer, B R; Stephens, G (1992. ) The induction of immunologic hyporesponsiveness by preoperative donor-specific transfusions and cyclosporine in human cadaveric transplants. A preliminary trial. Transplantation, , 53 (2 ) ,423-7

De Stefano, J A; Sleight, R G; Babcock, G F; Sramkoski, R M; Walzer, P D (1992. ) Isolation of Pneumocystis carinii cysts by flow cytometry. Parasitology research, , 78 (3 ) ,179-82

Alexander, J W; Gianotti, L; Pyles, T; Carey, M A; Babcock, G F (1991. ) Distribution and survival of Escherichia coli translocating from the intestine after thermal injury. Annals of surgery, , 213 (6 ) ,558-66; discussion 5

Amoscato, A A; Sramkoski, R M; Babcock, G F; Alexander, J W (1990. ) Neutral surface aminopeptidase activity of human tumor cell lines. Biochimica et biophysica acta, , 1041 (3 ) ,317-9

Alexander, J W; Boyce, S T; Babcock, G F; Gianotti, L; Peck, M D; Dunn, D L; Pyles, T; Childress, C P; Ash, S K (1990. ) The process of microbial translocation. Annals of surgery, , 212 (4 ) ,496-510; discussion

Sasamoto, Y; Alexander, J W; Babcock, G F Prolonged survival of reconstituted skin grafts without immunosuppression. The Journal of burn care & rehabilitation, , 11 (3 ) ,190-200

Fang, C H; Peck, M D; Alexander, J W; Babcock, G F; Warden, G D (1990. ) The effect of free radical scavengers on outcome after infection in burned mice. The Journal of trauma, , 30 (4 ) ,453-6

Peck, M D; Alexander, J W; Ogle, C K; Babcock, G F (1990. ) The effect of dietary fatty acids on response to Pseudomonas infection in burned mice. The Journal of trauma, , 30 (4 ) ,445-52

Babcock, G F; Alexander, J W; Warden, G D (1990. ) Flow cytometric analysis of neutrophil subsets in thermally injured patients developing infection. Clinical immunology and immunopathology, , 54 (1 ) ,117-25

Perez, R V; Babcock, G F; Alexander, J W (1989. ) Immunoregulation of transfusion-induced immunosuppression with inhibitors of the arachidonic acid metabolism. Transplantation, , 48 (1 ) ,85-7

Amoscato, A A; Alexander, J W; Babcock, G F (1989. ) Surface aminopeptidase activity of human lymphocytes. I. Biochemical and biologic properties of intact cells. Journal of immunology (Baltimore, Md. : 1950), , 142 (4 ) ,1245-52

Babcock, G F; Smith, L A; Alexander, J W (1988. ) A comparison of single and multiple blood transfusions in the mixed lymphocyte response of rats. Transplantation proceedings, , 20 (6 ) ,1213-6

Amoscato, A A; Balasubramaniam, A; Alexander, J W; Babcock, G F (1988. ) Degradation of thymopentin by human lymphocytes: evidence for aminopeptidase activity. Biochimica et biophysica acta, , 955 (2 ) ,164-74

Zhao, X F; Schroeder, T J; Alexander, J W; Miskell, P; Gonce, S J; Babcock, G F (1988. ) The prolongation of skin allograft survival by topical use of cyclosporine A. Transplantation proceedings, , 20 (2 Suppl 2 ) ,670-3

Babcock, G F (1988. ) Workshop on flow cytometry methodologies. Cytometry. Supplement : the journal of the Society for Analytical Cytology, , 3 ,106-7

Lai, C S; Wesseler, T A; Alexander, J W; Babcock, G F (1987. ) Long-term survival of skin allografts in rats treated with topical cyclosporine. Transplantation, , 44 (1 ) ,83-7

Bowlin, T L; McKown, B J; Babcock, G F; Sunkara, P S (1987. ) Intracellular polyamine biosynthesis is required for interleukin 2 responsiveness during lymphocyte mitogenesis. Cellular immunology, , 106 (2 ) ,420-7

Babcock, G F; Taylor, A F; Hynd, B A; Sramkoski, R M; Alexander, J W (1987. ) Flow cytometric analysis of lymphocyte subset phenotypes comparing normal children and adults. Diagnostic and clinical immunology, , 5 (4 ) ,175-9

Banks, R A; Nishioka, K; Kazazi, F; Babcock, G F (1985. ) Effect of tuftsin on in vivo development of 3-methylcholanthrene-induced primary fibrosarcoma and Lewis lung carcinoma in mice. Journal of the National Cancer Institute, , 74 (5 ) ,1079-83

Schantz, S P; Romsdahl, M M; Babcock, G F; Nishioka, K; Goepfert, H (1985. ) The effect of surgery on natural killer cell activity in head and neck cancer patients: in vitro reversal of a postoperatively suppressed immunosurveillance system. The Laryngoscope, , 95 (5 ) ,588-94

Pollock, R E; Babcock, G F; Romsdahl, M M; Nishioka, K (1984. ) Surgical stress-mediated suppression of murine natural killer cell cytotoxicity. Cancer research, , 44 (9 ) ,3888-91

Nishioka, K; Amoscato, A A; Babcock, G F; Banks, R A; Phillips, J H (1984. ) Tuftsin: an immunomodulating peptide hormone and its clinical potential as a natural biological response modifier. Cancer investigation, , 2 (1 ) ,39-49

Lanier, L L; Phillips, J H; Warner, N L; Babcock, G F (1984. ) A human natural killer cell-associated antigen defined by monoclonal antibody anti-Leu (NKP-15): functional and two-color flow cytometry analysis. Journal of leukocyte biology, , 35 (1 ) ,11-7

Lanier, L L; Le, A M; Phillips, J H; Warner, N L; Babcock, G F (1983. ) Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens. Journal of immunology (Baltimore, Md. : 1950), , 131 (4 ) ,1789-96

Phillips, J H; Nishioka, K; Babcock, G F (1983. ) Tuftsin-induced enhancement of murine and human natural cell-mediated cytotoxicity. Annals of the New York Academy of Sciences, , 419 ,192-204

Lanier, L L; Engleman, E G; Gatenby, P; Babcock, G F; Warner, N L; Herzenberg, L A (1983. ) Correlation of functional properties of human lymphoid cell subsets and surface marker phenotypes using multiparameter analysis and flow cytometry. Immunological reviews, , 74 ,143-60

Babcock, G F; Phillips, J H (1983. ) Human NK cells: light and electron microscopic characteristics. Survey of immunologic research, , 2 (1 ) ,88-101

Nishioka, K; Babcock, G F; Phillips, J H; Noyes, R D (1981. ) Antitumor effect of tuftsin. Molecular and cellular biochemistry, , 41 ,13-8

Lanier, L L; Babcock, G F; Raybourne, R B; Arnold, L W; Warner, N L; Haughton, G (1980. ) Mechanism of B cell lymphoma immunotherapy with passive xenogeneic anti-idiotype serum. Journal of immunology (Baltimore, Md. : 1950), , 125 (4 ) ,1730-6

Lanier, L L; Babcock, G F; Lynes, M A; Haughton, G (1979. ) Antigen-induced murine B-cell lymphomas. III. Passive anti-idiotype serum therapy and its combined effect with chemotherapy. Journal of the National Cancer Institute, , 63 (6 ) ,1417-22

Banks, R A; Babcock, G F; Whitmore, A C; Haughton, G (1979. ) Effect of immunologic intervention on in vivo murine Rous sarcoma virus tumorigenesis. Journal of the National Cancer Institute, , 63 (6 ) ,1423-31

Lynes, M A; Lanier, L L; Babcock, G F; Wettstein, P J; Haughton, G (1978. ) Antigen-induced murine B cell lymphomas. I. Induction and characterization of CH1 and CH2. Journal of immunology (Baltimore, Md. : 1950), , 121 (6 ) ,2352-7

Haughton, G; Lanier, L L; Babcock, G F (1978. ) The murine kappa light chain shift. Nature, , 275 (5676 ) ,154-7

Whitmore, A C; Babcock, G F; Haughton, G (1978. ) Genetic control of susceptibility of mice to Rous sarcoma virus tumorigenesis. II. Segregation analysis of strain A.SW-associated resistance to primary tumor induction. Journal of immunology (Baltimore, Md. : 1950), , 121 (1 ) ,213-20

Babcock, G F; Lanier, L L; Lynes, M A; Haughton, G (1978. ) A simple method for the preparation of antisera specific for murine immunoglobulin heavy chains. Journal of immunological methods, , 23 (1-2 ) ,1-6

McCarthy, R E; Arnold, L W; Babcock, G F (1977. ) Dextran sulphate: an adjuvant for cell-mediated immune responses. Immunology, , 32 (6 ) ,963-74

Lanier L.;Babcock G.;Lynes M.;Haughton G. (01-01-1979. ) Curative passive immunotherapy of a murine B cell lymphoma with anti-idiotype serum (A-Id) .Proceedings of the American Association for Cancer Research, , Vol. 20 ,

Lanier L.;Babcock G.;Lynes M.;Haughton G. (01-01-1979. ) Anti-idiotype antiserum (A-Id) therapy and its synergistic effect with chemotherapy in the treatment .Federation Proceedings, , 38 (3 II ) ,

Romsdahl M.;Babcock G.;Phillips J.;Nishioka K. (01-01-1981. ) The immunopotentiating effect of tuftsin on human natural cell-mediated cytotoxicity .Proceedings of the American Association for Cancer Research, , Vol. 22 ,1086

Lewis D.;Babcock G.;Templeton J. (01-01-1984. ) A rapid and sensitive flow cytometric method for measuring cell and antibody mediated cytotoxicity .Federation Proceedings, , 43 (6 ) ,

Weiner D.B.;Watson S.R.;Babcock G.;Keller S.J. (01-01-1986. ) Expression of human T antigens in interspecies hybridomas.Cellular Immunology, , 100 (1 ) ,197-209 More Information

Lai C.;Babcock G.;Alexander J. (01-01-1986. ) Indefinite survival of rat skin allografts induced by topical cyclosporin A .Surgical Forum, , 37 ,603-604

Perez R.;Heyd T.;Munda R.;Babcock G.;Alexander J. (01-01-1988. ) Induction of long-term rat cardiac allograft survival in rats with multiple donor specific transfusi .Current Surgery, , 45 (1 ) ,9-12

Banks R.;Babcock G.;Nishioka K. (01-01-1988. ) Effect of oral administered or liposome-encapsulated tuftsin on survival of C57BL/6 mic inoculated w .Journal of Experimental and Clinical Cancer Research, , 7 (1 ) ,21-26

Wolos J.;Frondorf K.;Babcock G.;Stripp S.;Bowlin T. (01-01-1993. ) Immunomodulation by an inhibitor of s-adenosyl-l-homocysteine hydrolase: Inhibition of in vitro and .Cellular Immunology, , 149 (2 ) ,402-408 More Information

ABDEL?MALEK Z.;SWOPE V.;SMALARA D.;BABCOCK G.;DAWES S.;NORDLUND J. (01-01-1994. ) Analysis of the UV?Induced Melanogenesis and Growth Arrest of Human Melanocytes.Pigment Cell Research, , 7 (5 ) ,326-332 More Information

Nordlund J.;Csato M.;Babcock G.;Takei F. (01-01-1995. ) Low ICAM?1 expression in the epidermis of depigmenting C57BL/6J?mivit/mi.Experimental Dermatology, , 4 (1 ) ,20-29 More Information

Barker D.;Smalara D.;Im S.;Abdel-Malek Z.;Dixon K.;Mitchell D.;Babcock G.;Medrano E. (09-15-1995. ) Comparison of the Responses of Human Melanocytes with Different Melanin Contents to Ultraviolet B Ir .Cancer Research, , 55 (18 ) ,4041-4046

Tada A.;Suzuki I.;Im S.;Davis M.;Cornelius J.;Babcock G.;Nordlund J.;Abdel-Malek Z. (01-01-1998. ) Endothelin-1 is a paracrine growth factor that modulates melanogenesis of human melanocytes and part .Cell Growth and Differentiation, , 9 (7 ) ,575-584

Alexander J.;Levy A.;Custer D.;Valente J.;Babcock G.;Ogle C.;Schroeder T. (01-01-1998. ) Arginine, fish oil, and donor-specific transfusions independently improve cardiac allograft survival.Journal of Parenteral and Enteral Nutrition, , 22 (3 ) ,152-155 More Information

Im S.;Moro O.;Peng F.;Medrano E.;Cornelius J.;Babcock G.;Nordlund J.;Abdel-Malek Z. (01-01-1998. ) Activation of the cyclic AMP pathway by ?-melanotropin mediates the response of human melanocytes to .Cancer Research, , 58 (1 ) ,47-54

Alexander J.W.;Valente J.F.;Greenberg N.A.;Custer D.A.;Ogle C.K.;Gibson S.;Babcock G. (02-01-1999. ) Dietary amino acids as new and novel agents to enhance allograft survival.Nutrition, , 15 (2 ) ,130-134 More Information

Sarangarajan R.;Zhao Y.;Babcock G.;Cornelius J.;Lynn Lamoreux M.;Boissy R.E. (10-21-2000. ) Mutant alleles at the brown locus encoding tyrosinase-related protein-1 (TRP-1) affect proliferation.Pigment Cell Research, , 13 (5 ) ,337-344 More Information

Le Poole I.C.;Boissy R.E.;Sarancarajan R.;Chen J.;Forristal J.J.;Sheth P.;Westerhof W.;Babcock G.;Das P.K.;Saelinger C.B. (05-01-2000. ) PIG3V, an immortalized human vitiligo melanocyte cell line, expresses dilated endoplasmic reticulum .In Vitro Cellular and Developmental Biology - Animal, , 36 (5 ) ,309-319

O'Brien T.;Babcock G.;Cornelius J.;Dingeldein M.;Talaska G.;Warshawsky D.;Mitchell K. (05-01-2000. ) A comparison of apoptosis and necrosis induced by hepatotoxins in HepG2 cells.Toxicology and Applied Pharmacology, , 164 (3 ) ,280-290 More Information

Healy D.;Silverman P.;Neely A.;Holder I.;Babcock G. (01-01-2002. ) Effect of antibiotics on polymorphonuclear neutrophil apoptosis.Pharmacotherapy, , 22 (5 ) ,578-585 More Information

Heinen C.;Goss K.;Cornelius J.;Babcock G.;Knudsen E.;Kowalik T.;Groden J. (01-01-2002. ) The APC tumor suppressor controls entry into S-phase through its ability to regulate the cyclin D/RB.Gastroenterology, , 123 (3 ) ,751-763 More Information

Healy D.;Enzweiler K.;Neely A.;Holder I.;Babcock G. (12-01-2004. ) Differential effects of amphotericin B and fluconazole on neutrophil CD11b expression.Journal of Infectious Disease Pharmacotherapy, , 6 (4 ) ,59-74 More Information

Lanier L.;Lynes M.;Babcock G. (01-01-1978. ) Immunodiagnosis and immunotherapy of a murine B cell lymphoma with a xenogeneic anti-idiotype antise .Federation Proceedings, , 37 (6 ) ,

Kadekaro A.;Kavanagh R.;Kanto H.;Terzieva S.;Hauser J.;Kobayashi N.;Schwemberger S.;Cornelius J.;Babcock G.;Shertzer H.;Scott G.;Abdel-Malek Z. (05-15-2005. ) ?-melanocortin and endothelin-1 activate antiapoptotic pathways and reduce DNA damage in human melan.Cancer Research, , 65 (10 ) ,4292-4299 More Information

Greatens A.;Hakozaki T.;Koshoffer A.;Epstein H.;Schwemberger S.;Babcock G.;Bissett D.;Takiwaki H.;Arase S.;Wickett R.R.;Boissy R.E. (07-01-2005. ) Effective inhibition of melanosome transfer to keratinocytes by lectins and niacinamide is reversibl.Experimental Dermatology, , 14 (7 ) ,498-508 More Information

Knauf J.;Ouyang B.;Knudsen E.;Fukasawa K.;Babcock G.;Fagin J. (02-17-2006. ) Oncogenic RAS induces accelerated transition through G2/M and promotes defect.Journal of Biological Chemistry, , 281 (7 ) ,3800-3809 More Information

Hauser J.;Kadekaro A.;Kavanagh R.;Wakamatsu K.;Terzieva S.;Schwemberger S.;Babcock G.;Rao M.;Ito S.;Abdel-Malek Z. (08-01-2006. ) Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human mela.Pigment Cell Research, , 19 (4 ) ,303-314 More Information

Swope V.;Supp A.;Schwemberger S.;Babcock G.;Boyce S. (10-01-2006. ) Increased expression of integrins and decreased apoptosis correlate with increased melanocyte retent.Pigment Cell Research, , 19 (5 ) ,424-433 More Information

Babcock G.;Rodeberg D. (12-01-1996. ) Effects of heat shock on human neutrophil degranulation .FASEB Journal, , 10 (6 ) ,

Babcock G.;Meyer J. (03-20-1998. ) The effects of stress on neutrophil function receptor expression, and apoptosis .FASEB Journal, , 12 (5 ) ,

Abdel-Malek Z.A.;Kadekaro A.L.;Kavanagh R.J.;Todorovic A.;Koikov L.N.;McNulty J.C.;Jackson P.J.;Millhauser G.L.;Schwemberger S.;Babcock G.;Haskell-Luevano C.;Knittel J.J. (07-01-2006. ) Melanoma prevention strategy based on using tetrapeptide ?-MSH analogs that protect human melanocyte.FASEB Journal, , 20 (9 ) , More Information

Dugan A.;Schwemberger S.;Noel G.;Babcock G.;Ogle C.;Horseman N. (02-01-2007. ) Psychogenic stress prior to burn injury has differential effects on bone marrow and cytokine respons .Experimental Biology and Medicine, , 232 (2 ) ,253-261

Abdala-Valencia H.;Earwood J.;Bansal S.;Jansen M.;Babcock G.;Garvy B.;Wills-Karp M.;Cook-Mills J. (05-01-2007. ) Nonhematopoietic NADPH oxidase regulation of lung eosinophilia and airway hyperresponsiveness in exp.American Journal of Physiology - Lung Cellular and Molecular Physiology, , 292 (5 ) , More Information

Weng D.;Zhang Y.;Hayashi Y.;Kuan C.;Liu C.;Babcock G.;Weng W.;Schwemberger S.;Kao W. (03-20-2008. ) Promiscuous recombination of LoxP alleles during gametogenesis in cornea Cre driver mice .Molecular Vision, , 14 ,562-571

Osterburg A.;Gardner J.;Hyon S.;Neely A.;Babcock G. (01-01-2009. ) Highly antibiotic-resistant Acinetobacter baumannii clinical isolates are killed by the green tea po.Clinical Microbiology and Infection, , 15 (4 ) ,341-346 More Information

Hayashi Y.;Call M.;Chikama T.;Liu H.;Carlson E.;Sun Y.;Pearlman E.;Funderburgh J.;Babcock G.;Liu C.;Ohashi Y.;Kao W. (09-01-2010. ) Lumican is required for neutrophil extravasation following corneal injury and wound healing.Journal of Cell Science, , 123 (17 ) ,2987-2995 More Information

Hayashi Y.;Call M.;Liu C.;Hayashi M.;Babcock G.;Ohashi Y.;Kao W. (09-01-2010. ) Monoallelic expression Of Krt12 gene during corneal-type epithelium differentiation Of limbal stem c.Investigative Ophthalmology and Visual Science, , 51 (9 ) ,4562-4568 More Information

Kadekaro A.L.;Leachman S.;Kavanagh R.J.;Swope V.;Cassidy P.;Supp D.;Sartor M.;Schwemberger S.;Babcock G.;Wakamatsu K.;Ito S.;Koshoffer A.;Boissy R.E.;Manga P.;Sturm R.A.;Abdel-Malek Z.A. (01-01-2010. ) Melanocortin 1 receptor genotype: An important determinant of the damage response of melanocytes to .FASEB Journal, , 24 (10 ) ,3850-3860 More Information

Tichy E.;Liang L.;Deng L.;Tischfield J.;Schwemberger S.;Babcock G.;Stambrook P. (04-03-2011. ) Mismatch and base excision repair proficiency in murine embryonic stem cells.DNA Repair, , 10 (4 ) ,445-451 More Information

Ebanks J.;Koshoffer A.;Wickett R.;Schwemberger S.;Babcock G.;Hakozaki T.;Boissy R. (01-01-2011. ) Epidermal keratinocytes from light vs. Dark skin exhibit differential degradation of melanosomes.Journal of Investigative Dermatology, , 131 (6 ) ,1226-1233 More Information

Swope V.B.;Jameson J.A.;McFarland K.L.;Supp D.M.;Miller W.E.;McGraw D.W.;Patel M.A.;Nix M.A.;Millhauser G.L.;Babcock G.F.;Abdel-Malek Z.A. (01-01-2012. ) Defining MC1R regulation in human melanocytes by its agonist ?-melanocortin and antagonists agouti s.Journal of Investigative Dermatology, , 132 (9 ) ,2255-2262 More Information

Osterburg A.;Mumy K.;Babcock G. (08-29-2013. ) Antibacterial -Acinetobacter baumannii - Activity of Epigallocatechin-3-Gallate (EGCG).Tea in Health and Disease Prevention, , 1195-1206 More Information

Swope V.;Alexander C.;Starner R.;Schwemberger S.;Babcock G.;Abdel-Malek Z. (01-01-2014. ) Significance of the melanocortin 1 receptor in the DNA damage response of human melanocytes to ultra.Pigment Cell and Melanoma Research, , 27 (4 ) ,601-610 More Information


Immunologist,Microbiologist,Cell Biologist,Transplantation Biologist,Immunity,Resistance to Cancer,Immunology,Antibodies,Antigens,Immunogenetics,Immunoregulation,Immunosuppression,Burns,Infectious Diseases,Nutrition and Immunity,Transfusion,Transfusion Problems,Flow Cytometry,Lymphatic,Reticuloendothelial

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Division of Burn Surgery,

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