George F. Babcock, PhD

Bachelor's Degree: Muskingum College 1970 (Biology)

Master's Degree: North Dakota State University 1972

Doctoral Degree: University of Nebraska Medical Center 1975 (Medical Microbiology and Immunology)

Postdoctoral Training: University of North Carolina 1978 (Microbiology and Immunology)

Immunology of Burns, Trauma and Infectious Disease

Grant: #SRS 002562 Investigators:Babcock, George 03-19-2007 -03-19-2012 Naval Health Research Center Navy Education Partnership Role:PI $.00 Active Level:Federal

Investigators:Babcock, George 08-01-2003 -07-31-2005 Thrasher Research Fund The Reduction of Infections in Seriously Burned Patients Role:PI $174,836.00 Closed Level:Private Non-Profit

Grant: #07-W911QY-08-P-0469 Investigators:Babcock, George 07-17-2008 -07-16-2009 Naval Health Research Center the Short and Long Term Immunological Response and Long Term Genotoxic Effects of Using Tungsten in Military Munitions Role:PI $80,393.00 Closed Level:Federal

Grant: #W911QY-08-P-0779 Investigators:Babcock, George 09-19-2008 -12-31-2009 Department of the Navy The Effects of Ingestion of Iraqi Particulate Matter on the Intestine and Immune System Role:PI $83,790.00 Closed Level:Federal

Grant: #1006754 Investigators:Babcock, George; Dugan, Amy; Horseman, Nelson 01-01-2009 -12-31-2009 Shriners Hospitals for Children - Cincinnati Shrine Physiology 2009 Consulting Agreements Role:Collaborator $175,036.00 Closed Level:Private Non-Profit

Grant: #W911QY-09-P-0706 Investigators:Babcock, George 09-29-2009 -09-28-2010 Office of Naval Research Effects of Environmental Toxins For Burn Injuries and Severe Trauma Role:PI $80,000.00 Active Level:Federal

Grant: #W911QY-10-C-0103 Investigators:Babcock, George 05-03-2010 -11-30-2011 Naval Health Research Center The Effects of Short-Term Exposure to Tungsten on the Immune Response Role:PI $159,963.00 Closed Level:Federal

Grant: #R21 EY021768 Investigators:Babcock, George; Kao, Winston Whei Yang; Liu, Hongshan 09-30-2011 -08-31-2015 National Eye Institute Cell Therapy of Corneal Diseases with Umbilical Mesenchyme Stem Cells Role:Collaborator $1,705,844.00 Active Level:Federal

Grant: #Prime W81XWH-11-2-0233-P00001 Investigators:Babcock, George; Healy, Daniel 09-30-2011 -03-30-2013 Department of the Army Medical Research Acquisition Activity The use of TheraGauze in the Treatment of Burn Wounds Role:PI $163,595.00 Active Level:Federal

Grant: #Prime W81XWH-11-2-0233-P00001 Investigators:Babcock, George; Healy, Daniel 09-30-2011 -03-30-2013 Department of the Army Medical Research Acquisition Activity The use of TheraGauze in the Treatment of Burn Wounds Role:PI $163,595.00 Closed Level:Federal

Grant: #LP- NCRADA-NMRC-15-9713 Investigators:Babcock, George 03-17-2016 -03-16-2017 Department of the Navy A Limited Purpose Coorperative Research and Development Agreement For Material Transfer Role:PI $.00 Active Level:Federal

Grant: #DoD1-SA1 / W81XWH-15-2-0065 Investigators:Babcock, George; Lentsch, Alex 01-01-2017 -12-31-2017 Department of the Army Medical Research Acquisition Activity Antimicrobial block copolypeptides (A-Blocks): Innovative Therapeutics and Prophylacics for Wound Infection Role:PI $517,802.00 Awarded Level:Federal

Grant: #AMIC-AW1 Investigators:Babcock, George 07-01-2018 -12-31-2018 Amicrobe, Inc. Antimicrobial block copolypeptides (A-Blocks): Innovative Therapeutics and Prophylacics for Wound Infection Role:PI $130,000.00 Active Level:Industry

Grant: #2019 Research Agreement Investigators:Babcock, George 01-01-2019 -03-31-2019 Rem Brands, Inc. Efficacy Study of a Test Compound in a Murine Infection Model Role:PI $45,496.00 Active Level:Industry

Peer Reviewed Publications

Osterburg, Andrew R; Hexley, Philip; Supp, Dorothy M; Robinson, Chad T; Noel, Greg; Ogle, Cora; Boyce, Steven T; Aronow, Bruce J; Babcock, George F  (2013). Concerns over interspecies transcriptional comparisons in mice and humans after trauma. Proceedings of the National Academy of Sciences of the United States of America, 110 (36) , E3370More Information

Swope, Viki B; Jameson, Joshua A; McFarland, Kevin L; Supp, Dorothy M; Miller, William E; McGraw, Dennis W; Patel, Mira A; Nix, Matthew A; Millhauser, Glenn L; Babcock, George F; Abdel-Malek, Zalfa A  (2012). Defining MC1R regulation in human melanocytes by its agonist ?-melanocortin and antagonists agouti signaling protein and ?-defensin 3. The Journal of investigative dermatology, 132 (9) , 2255-62More Information

Tichy, Elisia D; Pillai, Resmi; Deng, Li; Tischfield, Jay A; Hexley, Philip; Babcock, George F; Stambrook, Peter J  (2012). The abundance of Rad51 protein in mouse embryonic stem cells is regulated at multiple levels. Stem cell research, 9 (2) , 124-34More Information

Hexley, Philip; Robinson, Chad T; Osterburg, Andrew R; Babcock, George F  (2012). Circulating microparticles do not all share biophysical light scatter properties with immune complexes when analyzed by flow cytometry. Blood, 120 (7) , 1528-9More Information

Babcock, George F; Hernandez, Laura; Yadav, Ekta; Schwemberger, Sandy; Dugan, Amy  (2012). The burn wound inflammatory response is influenced by midazolam. Inflammation, 35 (1) , 259-70More Information

Kavanaugh, Gina M; Wise-Draper, Trisha M; Morreale, Richard J; Morrison, Monique A; Gole, Boris; Schwemberger, Sandy; Tichy, Elisia D; Lu, Lu; Babcock, George F; Wells, James M; Drissi, Rachid; Bissler, John J; Stambrook, Peter J; Andreassen, Paul R; Wiesmüller, Lisa; Wells, Susanne I  (2011). The human DEK oncogene regulates DNA damage response signaling and repair. Nucleic acids research, 39 (17) , 7465-76More Information

Tichy, Elisia D; Pillai, Resmi; Deng, Li; Liang, Li; Tischfield, Jay; Schwemberger, Sandy J; Babcock, George F; Stambrook, Peter J  (2010). Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks. Stem cells and development, 19 (11) , 1699-711More Information

Jacobson, Eric M; Yang, Heyi; Menconi, Francesca; Wang, Rong; Osman, Roman; Skrabanek, Luce; Li, Cheuk Wun; Fadlalla, Mohammed; Gandhi, Alisha; Chaturvedi, Vijaya; Smith, Eric P; Schwemberger, Sandy; Osterburg, Andrew; Babcock, George F; Tomer, Yaron  (2009). Employing a recombinant HLA-DR3 expression system to dissect major histocompatibility complex II-thyroglobulin peptide dynamism: a genetic, biochemical, and reverse immunological perspective. The Journal of biological chemistry, 284 (49) , 34231-43More Information

Bommireddy, R; Bueno, O F; Martin, J; Ormsby, I; Chen, H; Gard, C; Molkentin, J D; Boivin, G P; Babcock, G F; Doetschman, T  (2009). Calcineurin deficiency decreases inflammatory lesions in transforming growth factor beta1-deficient mice. Clinical and experimental immunology, 158 (3) , 317-24More Information

Azhar, Mohamad; Yin, Moying; Bommireddy, Ramireddy; Duffy, John J; Yang, Junqi; Pawlowski, Sharon A; Boivin, Gregory P; Engle, Sandra J; Sanford, L P; Grisham, Christina; Singh, Ram R; Babcock, George F; Doetschman, Thomas  (2009). Generation of mice with a conditional allele for transforming growth factor beta 1 gene. Genesis (New York, N.Y. : 2000), 47 (6) , 423-31More Information

Fumagalli, Stefano; Di Cara, Alessandro; Neb-Gulati, Arti; Natt, Francois; Schwemberger, Sandy; Hall, Jonathan; Babcock, George F; Bernardi, Rosa; Pandolfi, Pier Paolo; Thomas, George  (2009). Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction. Nature cell biology, 11 (4) , 501-8More Information

Bommireddy, Ramireddy; Babcock, George F; Singh, Ram R; Doetschman, Thomas  (2008). TGFbeta1 deficiency does not affect the generation and maintenance of CD4+CD25+FOXP3+ putative Treg cells, but causes their numerical inadequacy and loss of regulatory function. Clinical immunology (Orlando, Fla.), 127 (2) , 206-13More Information

Caldwell, Julie M; Chen, Yinhuai; Schollaert, Kaila L; Theis, James F; Babcock, George F; Newlon, Carol S; Sanchez, Yolanda  (2008). Orchestration of the S-phase and DNA damage checkpoint pathways by replication forks from early origins. The Journal of cell biology, 180 (6) , 1073-86More Information

Markey, M P; Bergseid, J; Bosco, E E; Stengel, K; Xu, H; Mayhew, C N; Schwemberger, S J; Braden, W A; Jiang, Y; Babcock, G F; Jegga, A G; Aronow, B J; Reed, M F; Wang, J Y J; Knudsen, E S  (2007). Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune function. Oncogene, 26 (43) , 6307-18More Information

Dugan, Amy L; Schwemberger, Sandy; Noel, Greg J; Babcock, George F; Ogle, Cora K; Buckley, Donna J; Horseman, Nelson D; Gregerson, Karen A  (2007). Stress and prolactin effects on bone marrow myeloid cells, serum chemokine and serum glucocorticoid levels in mice. Neuroimmunomodulation, 14 (6) , 287-96More Information

Wetherill, Yelena B; Hess-Wilson, Janet K; Comstock, Clay E S; Shah, Supriya A; Buncher, C Ralph; Sallans, Larry; Limbach, Patrick A; Schwemberger, Sandy; Babcock, George F; Knudsen, Karen E  (2006). Bisphenol A facilitates bypass of androgen ablation therapy in prostate cancer. Molecular cancer therapeutics, 5 (12) , 3181-90More Information

Bommireddy, Ramireddy; Pathak, Leena J; Martin, Jennifer; Ormsby, Ilona; Engle, Sandra J; Boivin, Gregory P; Babcock, George F; Eriksson, Anna U; Singh, Ram R; Doetschman, Thomas  (2006). Self-antigen recognition by TGF beta1-deficient T cells causes their activation and systemic inflammation. Laboratory investigation; a journal of technical methods and pathology, 86 (10) , 1008-19More Information

Mayhew, Christopher N; Bosco, Emily E; Fox, Sejal R; Okaya, Tomohisa; Tarapore, Pheruza; Schwemberger, Sandy J; Babcock, George F; Lentsch, Alex B; Fukasawa, Kenji; Knudsen, Erik S  (2005). Liver-specific pRB loss results in ectopic cell cycle entry and aberrant ploidy. Cancer research, 65 (11) , 4568-77More Information

Keshavan, Pavitra; Deem, Tracy L; Schwemberger, Sandy J; Babcock, George F; Cook-Mills, Joan M; Zucker, Stephen D  (2005). Unconjugated bilirubin inhibits VCAM-1-mediated transendothelial leukocyte migration. Journal of immunology (Baltimore, Md. : 1950), 174 (6) , 3709-18

Keshavan, Pavitra; Schwemberger, Sandy J; Smith, Darcey L H; Babcock, George F; Zucker, Stephen D  (2004). Unconjugated bilirubin induces apoptosis in colon cancer cells by triggering mitochondrial depolarization. International journal of cancer, 112 (3) , 433-45More Information

Babcock, George F  (2004). Common problems encountered by IACUCs--one chair's perspective. Contemporary topics in laboratory animal science, 43 (3) , 70-1

Babcock, George F  (2004). Intracellular cytokines. Current protocols in cytometry, Chapter 9, Unit 9.9More Information

Dugan, Amy L; Schwemberger, Sandy; Babcock, George F; Buckley, Donna; Buckley, Arthur R; Ogle, Cora K; Horseman, Nelson D  (2004). Effects of prolactin level on burn-induced aberrations in myelopoiesis. Shock (Augusta, Ga.), 21 (2) , 151-9More Information

Babcock, George F  (2003). Predictive medicine: severe trauma and burns. Cytometry. Part B, Clinical cytometry, 53 (1) , 48-53More Information

Bommireddy, Ramireddy; Saxena, Vijay; Ormsby, Ilona; Yin, Moying; Boivin, Gregory P; Babcock, George F; Singh, Ram R; Doetschman, Thomas  (2003). TGF-beta 1 regulates lymphocyte homeostasis by preventing activation and subsequent apoptosis of peripheral lymphocytes. Journal of immunology (Baltimore, Md. : 1950), 170 (9) , 4612-22

Bommireddy, Ramireddy; Ormsby, Ilona; Yin, Moying; Boivin, Gregory P; Babcock, George F; Doetschman, Thomas  (2003). TGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytes. Journal of immunology (Baltimore, Md. : 1950), 170 (7) , 3645-52

Heinen, Christopher D; Goss, Kathleen Heppner; Cornelius, James R; Babcock, George F; Knudsen, Erik S; Kowalik, Timothy; Groden, Joanna  (2002). The APC tumor suppressor controls entry into S-phase through its ability to regulate the cyclin D/RB pathway. Gastroenterology, 123 (3) , 751-63

Gibson, S W; Valente, J F; Alexander, J W; Custer, D A; Li, B G; Frede, S; Babcock, G F; Ogle, C K  (2000). Nutritional immunomodulation leads to enhanced allograft survival in combination with cyclosporine A and rapamycin, but not FK506. Transplantation, 69 (10) , 2034-8

Le Poole, I C; Yang, F; Brown, T L; Cornelius, J; Babcock, G F; Das, P K; Boissy, R E  (1999). Altered gene expression in melanocytes exposed to 4-tertiary butyl phenol (4-TBP): upregulation of the A2b adenosine receptor 1. The Journal of investigative dermatology, 113 (5) , 725-31More Information

Rodeberg, D A; Meyer, J G; Babcock, G F  (1999). Heat shock response: presence and effects in burn patient neutrophils. Journal of leukocyte biology, 66 (5) , 773-80

Jawa, R S; Quaid, G A; Williams, M A; Cave, C M; Robinson, C T; Babcock, G F; Lieberman, M A; Witt, D; Solomkin, J S  (1999). Tumor necrosis factor alpha regulates CXC chemokine receptor expression and function. Shock (Augusta, Ga.), 11 (6) , 385-90

Gibson, S W; Valente, J F; Alexander, J W; Custer, D A; Babcock, G F; Ogle, C K  (1999). The effect of nutritional immunomodulation on cardiac allograft survival in rats receiving mycophenolate mofetil, cyclosporine A, and donor-specific transfusion. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 18 (3) , 185-9

Babcock, G F  (1999). Quantitation of phagocytosis by confocal microscopy. Methods in enzymology, 307, 319-28

King, K L; Moreira, K M; Babcock, G F; Wang, J; Campos, B; Kaetzel, M A; Dedman, J R  (1998). Temporal inhibition of calmodulin in the nucleus. Biochimica et biophysica acta, 1448 (2) , 245-53

Alexander, J W; Valente, J F; Greenberg, N A; Custer, D A; Ogle, C K; Gibson, S W; Babcock, G F  (1998). Dietary omega-3 and omega-9 fatty acids uniquely enhance allograft survival in cyclosporine-treated and donor-specific transfusion-treated rats. Transplantation, 65 (10) , 1304-9

Rodeberg, D A; Morris, R E; Babcock, G F  (1997). Azurophilic granules of human neutrophils contain CD14. Infection and immunity, 65 (11) , 4747-53

Swope, V B; Supp, A P; Cornelius, J R; Babcock, G F; Boyce, S T  (1997). Regulation of pigmentation in cultured skin substitutes by cytometric sorting of melanocytes and keratinocytes. The Journal of investigative dermatology, 109 (3) , 289-95

Levy, A E; Alexander, J W; Babcock, G F  (1997). A strategy for generating consistent long-term donor-specific tolerance to solid organ allografts. Transplant immunology, 5 (2) , 83-8

Rodeberg, D A; Bass, R C; Alexander, J W; Warden, G D; Babcock, G F  (1997). Neutrophils from burn patients are unable to increase the expression of CD11b/CD18 in response to inflammatory stimuli. Journal of leukocyte biology, 61 (5) , 575-82

Hess, K L; Babcock, G F; Askew, D S; Cook-Mills, J M  (1997). A novel flow cytometric method for quantifying phagocytosis of apoptotic cells. Cytometry, 27 (2) , 145-52

Goggins, W C; Fisher, R A; Dattilo, J B; Cohen, D S; Tawes, J W; Dattilo, M P; Babcock, G F; Frede, S E; Wakely, P E; Posner, M P  (1997). Analysis of functional renal allograft tolerance with single-dose rapamycin based induction immunosuppression. Transplantation, 63 (2) , 310-4

Frede, S E; Levy, A E; Alexander, J W; Babcock, G F  (1996). An examination of tissue chimerism in the ACI to Lewis rat cardiac transplant model. Transplant immunology, 4 (3) , 227-31

Gennari, R; Alexander, J W; Boyce, S T; Lilly, N; Babcock, G F; Cornaggia, M  (1996). Effects of the angiotensin converting enzyme inhibitor enalapril on bacterial translocation after thermal injury and bacterial challenge. Shock (Augusta, Ga.), 6 (2) , 95-100

Kane, T D; Johnson, S R; Alexander, J W; Babcock, G F; Ogle, C K  (1996). Detection of intestinal bacterial translocation using PCR. The Journal of surgical research, 63 (1) , 59-63More Information

Babcock, G F; Alexander, J W  (1996). The effects of blood transfusion on cytokine production by TH1 and TH2 lymphocytes in the mouse. Transplantation, 61 (3) , 465-8

Peck, M D; Babcock, G F; Alexander, J W; Billiar, T; Ochoa, J  (1995). High doses of dietary arginine during repletion impair weight gain and increase infectious mortality in protein-malnourished mice. The British journal of nutrition, 74 (6) , 787-95

Gennari, R; Alexander, J W; Eaves-Pyles, T; Babcock, G F  (1994). Heparan sulfate increases survival during gut-derived sepsis by decreasing bacterial translocation and enhancing host defense. Shock (Augusta, Ga.), 2 (4) , 246-50

Swope, V B; Sauder, D N; McKenzie, R C; Sramkoski, R M; Krug, K A; Babcock, G F; Nordlund, J J; Abdel-Malek, Z A  (1994). Synthesis of interleukin-1 alpha and beta by normal human melanocytes. The Journal of investigative dermatology, 102 (5) , 749-53

Solomkin, J S; Bass, R C; Bjornson, H S; Tindal, C J; Babcock, G F  (1994). Alterations of neutrophil responses to tumor necrosis factor alpha and interleukin-8 following human endotoxemia. Infection and immunity, 62 (3) , 943-7

Babcock, G F; Dawes, S M  (1994). Immunophenotyping using fixed cells. Methods in cell biology, 41, 81-93

De Stefano, J A; Foy, J M; Sullivan, D W; Dawes, S M; Cushion, M T; Babcock, G F; Sleight, R G; van Halbeek, H; Walzer, P D  (1994). Fractionation of Pneumocystis carinii developmental stages by counterflow centrifugal elutriation and sequential filtrations. Parasitology research, 80 (1) , 1-9

Gianotti, L; Munda, R; Alexander, J W; Tchervenkov, J I; Babcock, G F  (1993). Bacterial translocation: a potential source for infection in acute pancreatitis. Pancreas, 8 (5) , 551-8

Gianotti, L; Alexander, J W; Pyles, T; Fukushima, R; Babcock, G F  (1993). Prostaglandin E1 analogues misoprostol and enisoprost decrease microbial translocation and modulate the immune response. Circulatory shock, 40 (4) , 243-9

Wolos, J A; Frondorf, K A; Babcock, G F; Stripp, S A; Bowlin, T L  (1993). Immunomodulation by an inhibitor of S-adenosyl-L-homocysteine hydrolase: inhibition of in vitro and in vivo allogeneic responses. Cellular immunology, 149 (2) , 402-8More Information

White-Owen, C; Hartmann, S; Alexander, J W; Babcock, G F  (1993). Reduced PMN beta 2 integrins after trauma: a possible role for colony-stimulating factors. Clinical and experimental immunology, 92 (3) , 477-81

Gianotti, L; Pyles, T; Alexander, J W; Fukushima, R; Babcock, G F  (1993). Identification of the blood component responsible for increased susceptibility to gut-derived infection. Transfusion, 33 (6) , 458-65

White-Owen, C; Alexander, J W; Sramkoski, R M; Babcock, G F  (1992). Rapid whole-blood microassay using flow cytometry for measuring neutrophil phagocytosis. Journal of clinical microbiology, 30 (8) , 2071-6

Gianotti, L; Pyles, T; Alexander, J W; Babcock, G F; Carey, M A  (1992). Impact of blood transfusion and burn injury on microbial translocation and bacterial survival. Transfusion, 32 (4) , 312-7

Alexander, J W; Babcock, G F; First, M R; Davies, C B; Madden, R L; Munda, R; Penn, I; Fidler, J P; Cofer, B R; Stephens, G  (1992). The induction of immunologic hyporesponsiveness by preoperative donor-specific transfusions and cyclosporine in human cadaveric transplants. A preliminary trial. Transplantation, 53 (2) , 423-7

De Stefano, J A; Sleight, R G; Babcock, G F; Sramkoski, R M; Walzer, P D  (1992). Isolation of Pneumocystis carinii cysts by flow cytometry. Parasitology research, 78 (3) , 179-82

Alexander, J W; Gianotti, L; Pyles, T; Carey, M A; Babcock, G F  (1991). Distribution and survival of Escherichia coli translocating from the intestine after thermal injury. Annals of surgery, 213 (6) , 558-66; discussion 5

Amoscato, A A; Sramkoski, R M; Babcock, G F; Alexander, J W  (1990). Neutral surface aminopeptidase activity of human tumor cell lines. Biochimica et biophysica acta, 1041 (3) , 317-9

Alexander, J W; Boyce, S T; Babcock, G F; Gianotti, L; Peck, M D; Dunn, D L; Pyles, T; Childress, C P; Ash, S K  (1990). The process of microbial translocation. Annals of surgery, 212 (4) , 496-510; discussion

Sasamoto, Y; Alexander, J W; Babcock, G FProlonged survival of reconstituted skin grafts without immunosuppression. The Journal of burn care & rehabilitation, 11 (3) , 190-200

Fang, C H; Peck, M D; Alexander, J W; Babcock, G F; Warden, G D  (1990). The effect of free radical scavengers on outcome after infection in burned mice. The Journal of trauma, 30 (4) , 453-6

Peck, M D; Alexander, J W; Ogle, C K; Babcock, G F  (1990). The effect of dietary fatty acids on response to Pseudomonas infection in burned mice. The Journal of trauma, 30 (4) , 445-52

Babcock, G F; Alexander, J W; Warden, G D  (1990). Flow cytometric analysis of neutrophil subsets in thermally injured patients developing infection. Clinical immunology and immunopathology, 54 (1) , 117-25

Perez, R V; Babcock, G F; Alexander, J W  (1989). Immunoregulation of transfusion-induced immunosuppression with inhibitors of the arachidonic acid metabolism. Transplantation, 48 (1) , 85-7

Amoscato, A A; Alexander, J W; Babcock, G F  (1989). Surface aminopeptidase activity of human lymphocytes. I. Biochemical and biologic properties of intact cells. Journal of immunology (Baltimore, Md. : 1950), 142 (4) , 1245-52

Babcock, G F; Smith, L A; Alexander, J W  (1988). A comparison of single and multiple blood transfusions in the mixed lymphocyte response of rats. Transplantation proceedings, 20 (6) , 1213-6

Amoscato, A A; Balasubramaniam, A; Alexander, J W; Babcock, G F  (1988). Degradation of thymopentin by human lymphocytes: evidence for aminopeptidase activity. Biochimica et biophysica acta, 955 (2) , 164-74

Zhao, X F; Schroeder, T J; Alexander, J W; Miskell, P; Gonce, S J; Babcock, G F  (1988). The prolongation of skin allograft survival by topical use of cyclosporine A. Transplantation proceedings, 20 (2 Suppl 2) , 670-3

Babcock, G F  (1988). Workshop on flow cytometry methodologies. Cytometry. Supplement : the journal of the Society for Analytical Cytology, 3, 106-7

Lai, C S; Wesseler, T A; Alexander, J W; Babcock, G F  (1987). Long-term survival of skin allografts in rats treated with topical cyclosporine. Transplantation, 44 (1) , 83-7

Bowlin, T L; McKown, B J; Babcock, G F; Sunkara, P S  (1987). Intracellular polyamine biosynthesis is required for interleukin 2 responsiveness during lymphocyte mitogenesis. Cellular immunology, 106 (2) , 420-7

Babcock, G F; Taylor, A F; Hynd, B A; Sramkoski, R M; Alexander, J W  (1987). Flow cytometric analysis of lymphocyte subset phenotypes comparing normal children and adults. Diagnostic and clinical immunology, 5 (4) , 175-9

Banks, R A; Nishioka, K; Kazazi, F; Babcock, G F  (1985). Effect of tuftsin on in vivo development of 3-methylcholanthrene-induced primary fibrosarcoma and Lewis lung carcinoma in mice. Journal of the National Cancer Institute, 74 (5) , 1079-83

Schantz, S P; Romsdahl, M M; Babcock, G F; Nishioka, K; Goepfert, H  (1985). The effect of surgery on natural killer cell activity in head and neck cancer patients: in vitro reversal of a postoperatively suppressed immunosurveillance system. The Laryngoscope, 95 (5) , 588-94

Pollock, R E; Babcock, G F; Romsdahl, M M; Nishioka, K  (1984). Surgical stress-mediated suppression of murine natural killer cell cytotoxicity. Cancer research, 44 (9) , 3888-91

Nishioka, K; Amoscato, A A; Babcock, G F; Banks, R A; Phillips, J H  (1984). Tuftsin: an immunomodulating peptide hormone and its clinical potential as a natural biological response modifier. Cancer investigation, 2 (1) , 39-49

Lanier, L L; Phillips, J H; Warner, N L; Babcock, G F  (1984). A human natural killer cell-associated antigen defined by monoclonal antibody anti-Leu (NKP-15): functional and two-color flow cytometry analysis. Journal of leukocyte biology, 35 (1) , 11-7

Lanier, L L; Le, A M; Phillips, J H; Warner, N L; Babcock, G F  (1983). Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens. Journal of immunology (Baltimore, Md. : 1950), 131 (4) , 1789-96

Phillips, J H; Nishioka, K; Babcock, G F  (1983). Tuftsin-induced enhancement of murine and human natural cell-mediated cytotoxicity. Annals of the New York Academy of Sciences, 419, 192-204

Lanier, L L; Engleman, E G; Gatenby, P; Babcock, G F; Warner, N L; Herzenberg, L A  (1983). Correlation of functional properties of human lymphoid cell subsets and surface marker phenotypes using multiparameter analysis and flow cytometry. Immunological reviews, 74, 143-60

Babcock, G F; Phillips, J H  (1983). Human NK cells: light and electron microscopic characteristics. Survey of immunologic research, 2 (1) , 88-101

Nishioka, K; Babcock, G F; Phillips, J H; Noyes, R D  (1981). Antitumor effect of tuftsin. Molecular and cellular biochemistry, 41, 13-8

Lanier, L L; Babcock, G F; Raybourne, R B; Arnold, L W; Warner, N L; Haughton, G  (1980). Mechanism of B cell lymphoma immunotherapy with passive xenogeneic anti-idiotype serum. Journal of immunology (Baltimore, Md. : 1950), 125 (4) , 1730-6

Lanier, L L; Babcock, G F; Lynes, M A; Haughton, G  (1979). Antigen-induced murine B-cell lymphomas. III. Passive anti-idiotype serum therapy and its combined effect with chemotherapy. Journal of the National Cancer Institute, 63 (6) , 1417-22

Banks, R A; Babcock, G F; Whitmore, A C; Haughton, G  (1979). Effect of immunologic intervention on in vivo murine Rous sarcoma virus tumorigenesis. Journal of the National Cancer Institute, 63 (6) , 1423-31

Lynes, M A; Lanier, L L; Babcock, G F; Wettstein, P J; Haughton, G  (1978). Antigen-induced murine B cell lymphomas. I. Induction and characterization of CH1 and CH2. Journal of immunology (Baltimore, Md. : 1950), 121 (6) , 2352-7

Haughton, G; Lanier, L L; Babcock, G F  (1978). The murine kappa light chain shift. Nature, 275 (5676) , 154-7

Whitmore, A C; Babcock, G F; Haughton, G  (1978). Genetic control of susceptibility of mice to Rous sarcoma virus tumorigenesis. II. Segregation analysis of strain A.SW-associated resistance to primary tumor induction. Journal of immunology (Baltimore, Md. : 1950), 121 (1) , 213-20

Babcock, G F; Lanier, L L; Lynes, M A; Haughton, G  (1978). A simple method for the preparation of antisera specific for murine immunoglobulin heavy chains. Journal of immunological methods, 23 (1-2) , 1-6

McCarthy, R E; Arnold, L W; Babcock, G F  (1977). Dextran sulphate: an adjuvant for cell-mediated immune responses. Immunology, 32 (6) , 963-74

Lanier L.;Babcock G.;Lynes M.;Haughton G.  (01-01-1979). Curative passive immunotherapy of a murine B cell lymphoma with anti-idiotype serum (A-Id). Proceedings of the American Association for Cancer Research, Vol. 20

Lanier L.;Babcock G.;Lynes M.;Haughton G.  (01-01-1979). Anti-idiotype antiserum (A-Id) therapy and its synergistic effect with chemotherapy in the treatment. Federation Proceedings, 38 (3 II)

Romsdahl M.;Babcock G.;Phillips J.;Nishioka K.  (01-01-1981). The immunopotentiating effect of tuftsin on human natural cell-mediated cytotoxicity. Proceedings of the American Association for Cancer Research, Vol. 22, 1086

Lewis D.;Babcock G.;Templeton J.  (01-01-1984). A rapid and sensitive flow cytometric method for measuring cell and antibody mediated cytotoxicity. Federation Proceedings, 43 (6)

Weiner D.B.;Watson S.R.;Babcock G.;Keller S.J.  (01-01-1986). Expression of human T antigens in interspecies hybridomas. Cellular Immunology, 100 (1) , 197-209More Information

Lai C.;Babcock G.;Alexander J.  (01-01-1986). Indefinite survival of rat skin allografts induced by topical cyclosporin A. Surgical Forum, 37, 603-604

Perez R.;Heyd T.;Munda R.;Babcock G.;Alexander J.  (01-01-1988). Induction of long-term rat cardiac allograft survival in rats with multiple donor specific transfusi. Current Surgery, 45 (1) , 9-12

Banks R.;Babcock G.;Nishioka K.  (01-01-1988). Effect of oral administered or liposome-encapsulated tuftsin on survival of C57BL/6 mic inoculated w. Journal of Experimental and Clinical Cancer Research, 7 (1) , 21-26

Wolos J.;Frondorf K.;Babcock G.;Stripp S.;Bowlin T.  (01-01-1993). Immunomodulation by an inhibitor of s-adenosyl-l-homocysteine hydrolase: Inhibition of in vitro and . Cellular Immunology, 149 (2) , 402-408More Information

ABDEL?MALEK Z.;SWOPE V.;SMALARA D.;BABCOCK G.;DAWES S.;NORDLUND J.  (01-01-1994). Analysis of the UV?Induced Melanogenesis and Growth Arrest of Human Melanocytes. Pigment Cell Research, 7 (5) , 326-332More Information

Nordlund J.;Csato M.;Babcock G.;Takei F.  (01-01-1995). Low ICAM?1 expression in the epidermis of depigmenting C57BL/6J?mi^vit/mi. Experimental Dermatology, 4 (1) , 20-29More Information

Barker D.;Smalara D.;Im S.;Abdel-Malek Z.;Dixon K.;Mitchell D.;Babcock G.;Medrano E.  (09-15-1995). Comparison of the Responses of Human Melanocytes with Different Melanin Contents to Ultraviolet B Ir. Cancer Research, 55 (18) , 4041-4046

Tada A.;Suzuki I.;Im S.;Davis M.;Cornelius J.;Babcock G.;Nordlund J.;Abdel-Malek Z.  (01-01-1998). Endothelin-1 is a paracrine growth factor that modulates melanogenesis of human melanocytes and part. Cell Growth and Differentiation, 9 (7) , 575-584

Alexander J.;Levy A.;Custer D.;Valente J.;Babcock G.;Ogle C.;Schroeder T.  (01-01-1998). Arginine, fish oil, and donor-specific transfusions independently improve cardiac allograft survival. Journal of Parenteral and Enteral Nutrition, 22 (3) , 152-155More Information

Im S.;Moro O.;Peng F.;Medrano E.;Cornelius J.;Babcock G.;Nordlund J.;Abdel-Malek Z.  (01-01-1998). Activation of the cyclic AMP pathway by ?-melanotropin mediates the response of human melanocytes to. Cancer Research, 58 (1) , 47-54

Alexander J.W.;Valente J.F.;Greenberg N.A.;Custer D.A.;Ogle C.K.;Gibson S.;Babcock G.  (02-01-1999). Dietary amino acids as new and novel agents to enhance allograft survival. Nutrition, 15 (2) , 130-134More Information

Sarangarajan R.;Zhao Y.;Babcock G.;Cornelius J.;Lynn Lamoreux M.;Boissy R.E.  (10-21-2000). Mutant alleles at the brown locus encoding tyrosinase-related protein-1 (TRP-1) affect proliferation. Pigment Cell Research, 13 (5) , 337-344More Information

Le Poole I.C.;Boissy R.E.;Sarancarajan R.;Chen J.;Forristal J.J.;Sheth P.;Westerhof W.;Babcock G.;Das P.K.;Saelinger C.B.  (05-01-2000). PIG3V, an immortalized human vitiligo melanocyte cell line, expresses dilated endoplasmic reticulum. In Vitro Cellular and Developmental Biology - Animal, 36 (5) , 309-319

O'Brien T.;Babcock G.;Cornelius J.;Dingeldein M.;Talaska G.;Warshawsky D.;Mitchell K.  (05-01-2000). A comparison of apoptosis and necrosis induced by hepatotoxins in HepG2 cells. Toxicology and Applied Pharmacology, 164 (3) , 280-290More Information

Healy D.;Silverman P.;Neely A.;Holder I.;Babcock G.  (01-01-2002). Effect of antibiotics on polymorphonuclear neutrophil apoptosis. Pharmacotherapy, 22 (5) , 578-585More Information

Heinen C.;Goss K.;Cornelius J.;Babcock G.;Knudsen E.;Kowalik T.;Groden J.  (01-01-2002). The APC tumor suppressor controls entry into S-phase through its ability to regulate the cyclin D/RB. Gastroenterology, 123 (3) , 751-763More Information

Healy D.;Enzweiler K.;Neely A.;Holder I.;Babcock G.  (12-01-2004). Differential effects of amphotericin B and fluconazole on neutrophil CD11b expression. Journal of Infectious Disease Pharmacotherapy, 6 (4) , 59-74More Information

Lanier L.;Lynes M.;Babcock G.  (01-01-1978). Immunodiagnosis and immunotherapy of a murine B cell lymphoma with a xenogeneic anti-idiotype antise. Federation Proceedings, 37 (6)

Kadekaro A.;Kavanagh R.;Kanto H.;Terzieva S.;Hauser J.;Kobayashi N.;Schwemberger S.;Cornelius J.;Babcock G.;Shertzer H.;Scott G.;Abdel-Malek Z.  (05-15-2005). ?-melanocortin and endothelin-1 activate antiapoptotic pathways and reduce DNA damage in human melan. Cancer Research, 65 (10) , 4292-4299More Information

Greatens A.;Hakozaki T.;Koshoffer A.;Epstein H.;Schwemberger S.;Babcock G.;Bissett D.;Takiwaki H.;Arase S.;Wickett R.R.;Boissy R.E.  (07-01-2005). Effective inhibition of melanosome transfer to keratinocytes by lectins and niacinamide is reversibl. Experimental Dermatology, 14 (7) , 498-508More Information

Knauf J.;Ouyang B.;Knudsen E.;Fukasawa K.;Babcock G.;Fagin J.  (02-17-2006). Oncogenic RAS induces accelerated transition through G2/M and promotes defect. Journal of Biological Chemistry, 281 (7) , 3800-3809More Information

Hauser J.;Kadekaro A.;Kavanagh R.;Wakamatsu K.;Terzieva S.;Schwemberger S.;Babcock G.;Rao M.;Ito S.;Abdel-Malek Z.  (08-01-2006). Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human mela. Pigment Cell Research, 19 (4) , 303-314More Information

Swope V.;Supp A.;Schwemberger S.;Babcock G.;Boyce S.  (10-01-2006). Increased expression of integrins and decreased apoptosis correlate with increased melanocyte retent. Pigment Cell Research, 19 (5) , 424-433More Information

Babcock G.;Rodeberg D.  (12-01-1996). Effects of heat shock on human neutrophil degranulation. FASEB Journal, 10 (6)

Babcock G.;Meyer J.  (03-20-1998). The effects of stress on neutrophil function receptor expression, and apoptosis. FASEB Journal, 12 (5)

Abdel-Malek Z.A.;Kadekaro A.L.;Kavanagh R.J.;Todorovic A.;Koikov L.N.;McNulty J.C.;Jackson P.J.;Millhauser G.L.;Schwemberger S.;Babcock G.;Haskell-Luevano C.;Knittel J.J.  (07-01-2006). Melanoma prevention strategy based on using tetrapeptide ?-MSH analogs that protect human melanocyte. FASEB Journal, 20 (9) More Information

Dugan A.;Schwemberger S.;Noel G.;Babcock G.;Ogle C.;Horseman N.  (02-01-2007). Psychogenic stress prior to burn injury has differential effects on bone marrow and cytokine respons. Experimental Biology and Medicine, 232 (2) , 253-261

Abdala-Valencia H.;Earwood J.;Bansal S.;Jansen M.;Babcock G.;Garvy B.;Wills-Karp M.;Cook-Mills J.  (05-01-2007). Nonhematopoietic NADPH oxidase regulation of lung eosinophilia and airway hyperresponsiveness in exp. American Journal of Physiology - Lung Cellular and Molecular Physiology, 292 (5) More Information

Weng D.;Zhang Y.;Hayashi Y.;Kuan C.;Liu C.;Babcock G.;Weng W.;Schwemberger S.;Kao W.  (03-20-2008). Promiscuous recombination of LoxP alleles during gametogenesis in cornea Cre driver mice. Molecular Vision, 14, 562-571

Osterburg A.;Gardner J.;Hyon S.;Neely A.;Babcock G.  (01-01-2009). Highly antibiotic-resistant Acinetobacter baumannii clinical isolates are killed by the green tea po. Clinical Microbiology and Infection, 15 (4) , 341-346More Information

Hayashi Y.;Call M.;Chikama T.;Liu H.;Carlson E.;Sun Y.;Pearlman E.;Funderburgh J.;Babcock G.;Liu C.;Ohashi Y.;Kao W.  (09-01-2010). Lumican is required for neutrophil extravasation following corneal injury and wound healing. Journal of Cell Science, 123 (17) , 2987-2995More Information

Hayashi Y.;Call M.;Liu C.;Hayashi M.;Babcock G.;Ohashi Y.;Kao W.  (09-01-2010). Monoallelic expression Of Krt12 gene during corneal-type epithelium differentiation Of limbal stem c. Investigative Ophthalmology and Visual Science, 51 (9) , 4562-4568More Information

Kadekaro A.L.;Leachman S.;Kavanagh R.J.;Swope V.;Cassidy P.;Supp D.;Sartor M.;Schwemberger S.;Babcock G.;Wakamatsu K.;Ito S.;Koshoffer A.;Boissy R.E.;Manga P.;Sturm R.A.;Abdel-Malek Z.A.  (01-01-2010). Melanocortin 1 receptor genotype: An important determinant of the damage response of melanocytes to . FASEB Journal, 24 (10) , 3850-3860More Information

Tichy E.;Liang L.;Deng L.;Tischfield J.;Schwemberger S.;Babcock G.;Stambrook P.  (04-03-2011). Mismatch and base excision repair proficiency in murine embryonic stem cells. DNA Repair, 10 (4) , 445-451More Information

Ebanks J.;Koshoffer A.;Wickett R.;Schwemberger S.;Babcock G.;Hakozaki T.;Boissy R.  (01-01-2011). Epidermal keratinocytes from light vs. Dark skin exhibit differential degradation of melanosomes. Journal of Investigative Dermatology, 131 (6) , 1226-1233More Information

Swope V.B.;Jameson J.A.;McFarland K.L.;Supp D.M.;Miller W.E.;McGraw D.W.;Patel M.A.;Nix M.A.;Millhauser G.L.;Babcock G.F.;Abdel-Malek Z.A.  (01-01-2012). Defining MC1R regulation in human melanocytes by its agonist ?-melanocortin and antagonists agouti s. Journal of Investigative Dermatology, 132 (9) , 2255-2262More Information

Osterburg A.;Mumy K.;Babcock G.  (08-29-2013). Antibacterial -Acinetobacter baumannii - Activity of Epigallocatechin-3-Gallate (EGCG). Tea in Health and Disease Prevention, 1195-1206More Information

Swope V.;Alexander C.;Starner R.;Schwemberger S.;Babcock G.;Abdel-Malek Z.  (01-01-2014). Significance of the melanocortin 1 receptor in the DNA damage response of human melanocytes to ultra. Pigment Cell and Melanoma Research, 27 (4) , 601-610More Information

Chatterjee, Ranjit; Riddle, Tara M; Poskarbiewicz, Melisa K; Babcock, George F  (2021). A Novel Approach to Negative Pressure Wound Therapy: Use of High Suction Capillary Device to Improve Wound Healing. Military medicine, 186 (Suppl 1) , 364-369More Information

Immunologist,Microbiologist,Cell Biologist,Transplantation Biologist,Immunity,Resistance to Cancer,Immunology,Antibodies,Antigens,Immunogenetics,Immunoregulation,Immunosuppression,Burns,Infectious Diseases,Nutrition and Immunity,Transfusion,Transfusion Problems,Flow Cytometry,Lymphatic,Reticuloendothelial

Division of Burn Surgery,

Academic - Shriners Hospitals for Children - Cincinnati
Room 446
Cincinnati  Ohio, 45229
Phone: 513-872-6231
george.babcock@uc.edu