William Barrett

William L Barrett , M.D.

Department Chair

Co-Director UC Cancer Institute, Medical Director UC Barrett Cancer Center, Charles M. Barrett M.D. Endowed Chair and Professor

UC Health Barrett Cancer Center
Department of Radiation Oncology
234 Goodman Street, ML 0757
Cincinnati, Ohio 45267
Phone 513-584-8216
Fax 513-584-4007
Email barretwl@ucmail.uc.edu

Education

Bachelor's Degree: University of Virginia 1982 (Arts)

Medical Degree: University of Cincinnati College of Medicine 1987

Residency: University Hospital 1991 (Radiation Oncology)

Fellowship: Memorial Sloan-Kettering Cancer Center 1982 (Brachytherapy)

Internship: University Hospital 1988 (General Surgery)

Certifications

American Board of Radiology (Radiation Oncology) (Certification Date: 06-04-1992 )

Clinical Interests

Radiation Oncology

Malignant Melanoma

Thyroid Cancer

Adenocarcinoma

Adenomyosis

Adenosquamous Carcinoma

Adnexal Tumors

Adrenal Cancer

Adrenal Cortex Cancers

Adrenal Gland Cancers

Adrenal Rest Tumor

Adrenal Tumors

Adrenocortical Carcinoma

Advanced Skin Cancer

Anaplastic Thyroid Cancer

Angiocarcinoma

Angiosarcoma

Basal Cell Carcinoma

Basosquamous Carcinoma

Bladder Cancer

Bone cancer

Bone Cancer Sarcoma

Bone Tissue Cancers

Bowen's Disease

BRCA1 Genes

BRCA2 Genes

Breast Cancer

Cancer

Cervical Cancer

Cutaneous B-cell lymphoma

Cutaneous Lymphoma

Cutaneous Melanoma

Cutaneous T-cell lymphoma

Dermatofibrosarcoma Protuberans (DFSP)

Ductal Breast Carcinoma

Ductal Carcinoma

Dysgerminoma

Ear Canal Masses

Ear Cancer

Eccrine Porocarcinoma

Embryonal Carcinoma

Endocrine Cancers

Endometrial Cancer

Endometrial Stromal Sarcoma

Epithelioid Sarcoma

Esthesioneuroblastoma

Follicular Thyroid Cancer

Genitourinary Cancer

Giant Cell Tumor of Tendon Sheath

Gingival Cancers

Head and Neck Cancer

Hemangiosarcoma

Hurthle Cell Thyroid Cancer

Hypopharyngeal Cancers

Hypothalamic Cancers

Intraductal Carcinoma

Intraductal Noninfiltrating Carcinoma

Jaw Cancers

Krukenberg Tumor

Laryngeal Cancer

Leiomyosarcoma

Leydig Cell Tumor

Lip Cancer

Liposarcoma

Male Genitalia Cancers

Mandible Tumors

Melanoma

Merkel Cell Carcinoma

Metastasis Cancers

Mucoepidermoid Carcinoma

Muscle Tissue Cancers

Myxofibrosarcoma

Myxosarcoma

Nasal and Paranasal Tumors

Nasal Masses

Nasopharyngeal Carcinoma

Neck Masses

Neoplasm

Nose and Sinus Cavity Cancer

Oral Cancer

Oral Leukoplakia

Oropharyngeal Cancer

Otorhinolaryngeal Cancer

Palatal Cancers

Papillary Carcinoma

Papillary Thyroid Cancer

Paraganglioma

Paranasal Sinus Cancers

Parathyroid Cancer

Parotid Cancers

Parotid Disease

Parotid tumors

Pelvic Cancers

Penile Cancer

Pharyngeal Cancers

Phyllodes Tumor

Plasma Cell Cancers

Plasmacytoma

Prostate Cancer

Renal Cancer

Renal Cell Carcinoma

Salivary Gland Cancer

Sarcoma

Scrotal masses

Sebaceous Gland Cancer

Seminoma

Sertoli Cell Tumor

Sertoli-Leydig Cell Tumor

Sinonasal Skull Base Tumors

Skin Cancer

Spine Sarcoma

Squamous Cell Carcinoma

Synovial Sarcoma

Temporal Bone Cancer

Teratocarcinoma

Testicular Cancer

Throat Cancer

Thyroid and Parathyroid Disorders

Thyroid Crisis

Thyroid Nodules

Tracheal Tumors

Upper Jaw Cancers

Ureteral Cancer

Urethral Cancer

Urogenital Cancers

Urologic Cancer

Uterine Sarcoma

Vaginal Cancer

Vocal Cord Cancer

Vocal Fold Carcinoma In Situ

Vulvar Cancer

Specialities

Radiation Oncology

Research and Practice Interests

Radiation Oncology, Cancer, Oncology, Head & Neck Cancer, Prostate Cancer, Sarcoma, Brachytherapy

Positions and Work Experience

2010 -To Present Medical Director, UC Barrett Cancer Center, UC Health / University Hospital, Cincinnati, OH

09-2008 -To Present Professor, Department of Radiation Oncology, University of Cincinnati College of Medicine, Cincinnati, Ohio

2008 -To Present Chairman, Department of Radiation Oncology, University of Cincinnati College of Medicine, Cincinnati, OH

2007 -To Present Associate Director, Cincinnati Cancer Center, University of Cincinnati College of Medicine, Cincinnati, OH

2006 -2008 Director, Radiation Oncology Residency Program , University of Cincinnati College of Medicine, Cincinnati OH

06-2004 -08-2008 Associate Professor, Division of Radiation Oncology, Department of Radiology , University of Cincinnati College of Medicine, Cincinnati, Ohio

2002 -To Present Associate Director for Education and Community Outreach, UC Health / University Hospital Barrett Cancer Center, Cincinnati, OH

2002 -To Present Board Member, Precision Radiotherapy Inc., University Pointe, West Chester, OH

1999 -2008 Director, Division of Radiation Oncology, University of Cincinnati College of Medicine, Department of Radiation Oncology, Cincinnati, OH

06-1994 -05-2004 Assistant Professor, Department of Otolaryngology , Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio

09-1992 -05-2004 Assistant Professor, Division of Radiation Oncology, Department of Radiology , University of Cincinnati College of Medicine,

Research Support

Grant: #RPR-13 / AVENTIS-03-A0-S0-E0 Investigators:Barrett, William 02-07-2000 -12-31-2003 Rhone-Poulenc Rorer Pharmaceuticals Role of Docetaxel (Taxotere) as a Radiosensitizer in Prostate Cancer - An In-Vitro Study Role:PI $20,000.00 Closed Level:Industry

Grant: #415810 / DE-AC05-76RL01830 Investigators:Barrett, William; Greis, Kenneth; Lamba, Michael 06-22-2018 -04-30-2020 Department of Energy Ceium Irradiator Replacement Program - University of Cincinnati Proposal Number 463974 Role:Collaborator $203,000.00 Active Level:Federal

Publications

Peer Reviewed Publications

Mierzwa, Michelle L; Barrett, William L; Redmond, Kevin; Shirazi, Reza; Kastl, Ali; Kumar, Nitin; Buncher, Ralph (2008. ) Randomized trial to assess the efficacy of intraoperative steroid use in decreasing acute urinary retention after transperineal radioactive iodine-125 implantation for prostate cancer.Cancer, , 113 (9 ) ,2605-9 More Information

Mierzwa, Michelle L; McCluskey, Connie M; Barrett, William L; Lowy, Andrew; Sussman, Jeffrey; Sorger, Joel (2007. ) Interstitial brachytherapy for soft tissue sarcoma: A single institution experience.Brachytherapy, , 6 (4 ) ,298-303 More Information

Mishra, Mark V; Shirazi, Reza; Barrett, William L (2007. ) Incidence and clinical course of hemorrhagic radiation proctitis after iodine-125 prostate brachytherapy .Clinical genitourinary cancer, , 5 (6 ) ,397-400

Augsburger, James J; Schneider, Susan; Narayana, Ashwatha; Breneman, John C; Aron, Bernard S; Barrett, William L; Trichopoulos, Nikolaos (2004. ) Plaque radiotherapy for choroidal and ciliochoroidal melanomas with limited nodular extrascleral extension .Canadian journal of ophthalmology. Journal canadien d, , 39 (4 ) ,380-7

Gleich, Lyon L; Ryzenman, John; Gluckman, Jack L; Wilson, Keith M; Barrett, William L; Redmond, Kevin P (2004. ) Recurrent advanced (T3 or T4) head and neck squamous cell carcinoma: is salvage possible?.Archives of otolaryngology--head & neck surgery, , 130 (1 ) ,35-8 More Information

Barrett, William L; Gluckman, Jack L; Wilson, Keith M; Gleich, Lyon L (2004. ) A comparison of treatments of squamous cell carcinoma of the base of tongue: surgical resection combined with external radiation therapy, external radiation therapy alone, and external radiation therapy combined with interstitial radiation.Brachytherapy, , 3 (4 ) ,240-5 More Information

Barrett, William L; Kassing, William M; Shirazi, Reza (2004. ) Efficacy of brachytherapy for prostate cancer in African Americans compared with Caucasians.Brachytherapy, , 3 (1 ) ,30-3 More Information

Slate, Lawrence J; Elson, Howard R; Lamba, Michael A S; Kassing, William M; Soldano, Michael; Barrett, William L (2004. ) A Monte Carlo brachytherapy study for dose distribution prediction in an inhomogeneous medium.Medical dosimetry : official journal of the American Association of Medical Dosimetrists, , 29 (4 ) ,271-8 More Information

Mierzwa, Michelle L; Barrett, William L; Gluckman, Jack L (2003. ) Radiation therapy for recurrent orbital hemangioma.Head & neck, , 25 (5 ) ,412-5 More Information

Gleich, Lyon L; Collins, C Michael; Gartside, Peter S; Gluckman, Jack L; Barrett, William L; Wilson, Keith M; Biddinger, Paul W; Redmond, Kevin P (2003. ) Therapeutic decision making in stages III and IV head and neck squamous cell carcinoma .Archives of otolaryngology--head & neck surgery, , 129 (1 ) ,26-35

Barrett, William L; Gleich, Lyon; Wilson, Keith; Gluckman, Jack (2002. ) Organ preservation with interstitial radiation for base of tongue cancer .American journal of clinical oncology, , 25 (5 ) ,485-8

Robertson, M L; Gleich, L L; Barrett, W L; Gluckman, J L (2001. ) Base-of-tongue cancer: survival, function, and quality of life after external-beam irradiation and brachytherapy.The Laryngoscope, , 111 (8 ) ,1362-5 More Information

Barrett, W L; Aron, B S; Breneman, J C; Narayana, A; Redmond, K P (2001. ) Clinical oncology clerkship for third-year medical students .Journal of cancer education : the official journal of the American Association for Cancer Education, , 16 (4 ) ,182-4

Campbell, A C; Gleich, L L; Barrett, W L; Gluckman, J L (1999. ) Cancerous seeding of the tracheotomy site in patients with upper aerodigestive tract squamous cell carcinoma.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, , 120 (4 ) ,601-3 More Information

Barrett, W L; Gluckman, J L; Aron, B S (1997. ) Safety of radiating jejunal interposition grafts in head and neck cancer .American journal of clinical oncology, , 20 (6 ) ,609-12

Barrett, W L; First, M R; Aron, B S; Penn, I (1993. ) Clinical course of malignancies in renal transplant recipients .Cancer, , 72 (7 ) ,2186-9

McFadden, D W; Kelley, D J; Sigmund, D A; Barrett, W L; Dickson, B; Aron, B S (1992. ) Embryonal sarcoma of the liver in an adult treated with preoperative chemotherapy, radiation therapy, and hepatic lobectomy .Cancer, , 69 (1 ) ,39-44

Barrett WL, Hertzfeld KE. (2010. ) Undetectable PSA level following prostate brachytherapy: An apples-to-apples comparison with radical prostatectomy. .UroToday: International Journal of Urologic Oncology 3(2)., , 3 (2 ) ,

Barrett WL, Breneman JC, Lavigne R, Redmond K, Elson H, Lamba M. (2011. ) Tribute to Dr. Bernard S. Aron. .Int. J. Radiation Oncology Biol. Phys., , 78 (2 ) ,323-324

Coombs C, Barrett WL, Hertzfeld KE. (2012. ) Outcomes in Transplant Patients Undergoing Brachytherapy for Prostate Cancer. .Am J Clin Oncol , , 35 (1 ) ,40-44

pater LE, Hart KW, Blonigen BJ, Lindsell CJ, Barrett WL. (2012. ) Relationship between prostate-specific antigen, age and body mass index in a prostate cancer screening population. .Am J Clin Oncol , , 35 (5 ) ,490-492

Hentz C, Barrett WL. (2014. ) Efficacy and Morbidity of Temporary I-125 Brachtherapy in Pediatric Rhabdomyosarcomas. .Brachytherapy , , 13 ,196-202

Marwaha G, Barrett WL. (2014. ) Stage III and IV head and neck cancer: Does everyone need chemotherapy? . Int. J. Otolaryngology and Head & Neck Surgery, , 3 ,26-28

Fakhry, Carole; Zhang, Qiang; Gillison, Maura L; Nguyen-Tân, Phuc Felix; Rosenthal, David I; Weber, Randal S; Lambert, Louise; Trotti, Andy M; Barrett, William L; Thorstad, Wade L; Yom, Sue S; Wong, Stuart J; Ridge, John A; Rao, Shyam S D; Spencer, Sharon; Fortin, Andre; Raben, David; Harris, Jonathan; Le, Quynh-Thu (2019. ) Validation of NRG oncology/RTOG-0129 risk groups for HPV-positive and HPV-negative oropharyngeal squamous cell cancer: Implications for risk-based therapeutic intensity trials.Cancer, , 125 (12 ) ,2027-2038 More Information

Davis, Harold W; Vallabhapurapu, Subrahmanya D; Chu, Zhengtao; Vallabhapurapu, Swarajya L; Franco, Robert S; Mierzwa, Michelle; Kassing, William; Barrett, William L; Qi, Xiaoyang (2019. ) Enhanced phosphatidylserine-selective cancer therapy with irradiation and SapC-DOPS nanovesicles.Oncotarget, , 10 (8 ) ,856-868 More Information

Eckman MH, Ying J, Hertzfeld K, Kumar N, Barrett WL. (2010. ) Longitudinal Analysis of Genitourinary and Bowel Symptoms in Prostate Cancer Patients Following Brachytherapy .Am J Clin Oncol , , 33 (1 ) ,1 --10

Fakhry, Carole; Nguyen-Tân, Phuc Felix; Lambert, Louise; Rosenthal, David I; Weber, Randal S; Gillison, Maura L; Trotti, Andy M; Barrett, William L; Thorstad, Wade L; Jones, Christopher U; Yom, Sue S; Wong, Stuart J; Ridge, John A; Rao, Shyam S D; Bonner, James A; Vigneault, Eric; Raben, David; Kudrimoti, Mahesh R; Harris, Jonathan; Le, Quynh-Thu (2018. ) In Regard to Bossi et al.International journal of radiation oncology, biology, physics, , 102 (3 ) ,669-670 More Information

Barrett WL, Hertzfeld KE. (2010. ) Undetectable PSA level following prostate brachytherapy: An apples-to-apples comparison with radical prostatectomy. .Uro Today, ,

Fakhry, Carole; Zhang, Qiang; Nguyen-Tân, Phuc Felix; Rosenthal, David I; Weber, Randal S; Lambert, Louise; Trotti, Andy M; Barrett, William L; Thorstad, Wade L; Jones, Christopher U; Yom, Sue S; Wong, Stuart J; Ridge, John A; Rao, Shyam S D; Bonner, James A; Vigneault, Eric; Raben, David; Kudrimoti, Mahesh R; Harris, Jonathan; Le, Quynh-Thu; Gillison, Maura L (2017. ) Development and Validation of Nomograms Predictive of Overall and Progression-Free Survival in Patients With Oropharyngeal Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 35 (36 ) ,4057-4065 More Information

Pater, Luke E; Hart, Kimberly W; Blonigen, Brian J; Lindsell, Christopher J; Barrett, William L (2012. ) Relationship between prostate-specific antigen, age, and body mass index in a prostate cancer screening population.American journal of clinical oncology, , 35 (5 ) ,490-2 More Information

Adamson, P; Auty, D J; Ayres, D S; Backhouse, C; Barr, G; Barrett, W L; Bishai, M; Blake, A; Bock, G J; Boehnlein, D J; Bogert, D; Bower, C; Budd, S; Cavanaugh, S; Cherdack, D; Childress, S; Choudhary, B C; Coelho, J A B; Cobb, J H; Coleman, S J; Corwin, L; Cravens, J P; Cronin-Hennessy, D; Danko, I Z; de Jong, J K; Devenish, N E; Diwan, M V; Dorman, M; Escobar, C O; Evans, J J; Falk, E; Feldman, G J; Frohne, M V; Gallagher, H R; Gomes, R A; Goodman, M C; Gouffon, P; Gran, R; Grant, N; Grzelak, K; Habig, A; Harris, D; Harris, P G; Hartnell, J; Hatcher, R; Himmel, A; Holin, A; Huang, X; Hylen, J; Ilic, J; Irwin, G M; Isvan, Z; Jaffe, D E; James, C; Jensen, D; Kafka, T; Kasahara, S M S; Koizumi, G; Kopp, S; Kordosky, M; Krahn, Z; Kreymer, A; Lang, K; Lefeuvre, G; Ling, J; Litchfield, P J; Loiacono, L; Lucas, P; Mann, W A; Marshak, M L; Mayer, N; McGowan, A M; Mehdiyev, R; Meier, J R; Messier, M D; Michael, D G; Miller, J L; Miller, W H; Mishra, S R; Mitchell, J; Moore, C D; Mualem, L; Mufson, S; Musser, J; Naples, D; Nelson, J K; Newman, H B; Nichol, R J; Oliver, W P; Orchanian, M; Paley, J; Patterson, R B; Patzak, T; Pawloski, G; Pearce, G F; Pittam, R; Plunkett, R K; Ratchford, J; Raufer, T M; Rebel, B; Rodrigues, P A; Rosenfeld, C; Rubin, H A; Ryabov, V A; Sanchez, M C; Saoulidou, N; Schneps, J; Schreiner, P; Semenov, V K; Shanahan, P; Smart, W; Sousa, A; Strait, M; Tagg, N; Talaga, R L; Thomas, J; Thomson, M A; Tinti, G; Toner, R; Tzanakos, G; Urheim, J; Vahle, P; Viren, B; Weber, A; Webb, R C; White, C; Whitehead, L; Wojcicki, S G; Wright, D M; Yang, T; Zois, M; Zwaska, R (2010. ) Search for Lorentz invariance and CPT violation with the MINOS far detector. Physical review letters, , 105 (15 ) ,151601

Eckman MH, Ying J, Hertzfeld K, Kumar N, Barrett WL. (02-2010. ) Longitudinal Analysis of Genitourinary and Bowel Symptoms in Prostate Cancer Patients Following Brachytherapy. Am J Clin Oncol 2010 , , 33 (1 ) ,1-10

Honors and Awards

2011 -2012 Best Doctors in America® Includes the nation’s most respected specialists and outstanding primary care physicians. Selected by peers

2010 Finalist for Jefferson Award for Public Service Cincinnati Rotary Club Status:Nomination Level:National Type:Recognition

2011 Best Doctors, Recognition by Peers Also in previous years: 2010, 2009, 2008, 2007, 2000, 1998 Cincinnati Magazine Status:Recipient Level:Regional Type:Recognition

2009 Health Care Hero, Finalist in Community Category Cincinnati Business Courier Status:Nomination Level:Regional

2009 Honoree, Ninth Annual Martin Luther King Jr. “Keep the Dream Alive” Award Ceremony , St. Mark’s Church, Cincinnati, Ohio Status:Recipient Level:Local

2006 Community Achievement Award American Cancer Society Status:Recipient Level:Regional Type:Recognition

2006 Distinguished Service Award Department of Otolaryngology/Head and Neck Surgery, University of Cincinnati Status:Recipient Level:University Type:Recognition

2006 Hero Award Nominee University Hospital, Cincinnati,OH Status:Nomination Level:Professional Org. Type:Recognition

2006 Honoree Closing the Health Care Gap Conference, Cincinnati Ohio Status:Recipient Level:Local

2005 Honoree Prostate Cancer Education, Research and Treatment Foundation Status:Recipient Level:National Type:Recognition

2005 Health Care Hero, Provider Category Cincinnati Business Courier Status:Recipient Level:Regional Type:Recognition

2004 Health Care Hero, Provider Category Cincinnati Business Courier Status:Recipient Level:Regional Type:Recognition

2004 Keynote Speaker, Volunteer and Cancer Survivor Recognition Banquet American Cancer Society of Southwest Ohio Level:Regional

2001 Honoree, Black Tie Gala American Cancer Society Status:Recipient Level:Regional Type:Recognition

2011 Honoree, Queen City Ball

Contact Information

Academic - UC Health Barrett Cancer Center
Department of Radiation Oncology
Cincinnati  Ohio, 45267
Phone: 513-584-8216
Fax: 513-584-4007
barretwl@ucmail.uc.edu