
Ishita Basu, PhD
Asst Professor - Research (F3)
Medical Sciences Building
5352B
COM Neurosurgery Basu Lab - 0515
Education
Doctoral Degree: University of Illinois Chicago, IL, 2012 (Electrical engineering)
Postdoctoral Fellowship: John Hopkins University Baltimore, MD, 2014
Research Fellowship: Massachusetts General Hospital Boston, MA, 2016
Research Instructor: Massachusetts General Hospital Boston, MA, 2020
Research and Practice Interests
1) Develop data driven and model based approaches for understanding brain rhythms underlying pathological states in patients with neurologic and psychiatric disorders.
2) Design brain stimulation paradigms for modulating pathologic brain dynamics towards healthy state.
Positions and Work Experience
10-2016 -05-2020 Instructor, Harvard Medical School, Boston
Research Support
Grant: #R21MH127009 Investigators:Basu, Ishita; Shear, Paula; Torres Reveron, Juan 04-01-2022 -03-31-2024 National Institute of Mental Health A neural population model-based characterization and modulation of neural oscillations underlying cognitive control in healthy and depressed/anxious human subjects Role:PI 202500.00 Awarded Level:Federal
Grant: #TP230311 Investigators:Basu, Ishita; Foreman, Brandon; Hartings, Jed; Jacquez, Farrah; Ngwenya, Laura; Shear, Paula 04-01-2024 -03-31-2027 Department of the Army Medical Research Acquisition Activity Early Neuromodulation for Cognitive Recovery and Rehabilitation in Traumatic Brain Injury Role:PI 810000.00 Hold Level:Federal
Grant: #R61MH133770 Investigators:Awosika, Oluwole; Basu, Ishita; Fleck, David; McElroy, Susan; Romo-Nava, Francisco; Welge, Jeffrey -02-28-2029 National Institute of Mental Health Modulating spinal interoceptive pathways to evaluate their role and therapeutic potential in MDD symptomatic domains Role:Collaborator 0.00 Hold Level:Federal
Publications
Peer Reviewed Publications
Yousefi, Ali; Basu, Ishita; Paulk, Angelique C; Peled, Noam; Eskandar, Emad N; Dougherty, Darin D; Cash, Sydney S; Widge, Alik S; Eden, Uri T (2019). Decoding Hidden Cognitive States From Behavior and Physiology Using a Bayesian Approach. Neural computation, 31 (9) , 1751-1788More Information
Yousefi, Ali; Paulk, Angelique C; Basu, Ishita; Mirsky, Jonathan L; Dougherty, Darin D; Eskandar, Emad N; Eden, Uri T; Widge, Alik S (2018). COMPASS: An Open-Source, General-Purpose Software Toolkit for Computational Psychiatry. Frontiers in neuroscience, 12, 957More Information
Basu, Ishita; Robertson, Madeline M; Crocker, Britni; Peled, Noam; Farnes, Kara; Vallejo-Lopez, Deborah I; Deng, Helen; Thombs, Matthew; Martinez-Rubio, Clarissa; Cheng, Jennifer J; McDonald, Eric; Dougherty, Darin D; Eskandar, Emad N; Widge, Alik S; Paulk, Angelique C; Cash, Sydney SConsistent linear and non-linear responses to invasive electrical brain stimulation across individuals and primate species with implanted electrodes. Brain stimulation, 12 (4) , 877-892More Information
Basu, Ishita; Crocker, Britni; Farnes, Kara; Robertson, Madeline M; Paulk, Angelique C; Vallejo, Deborah I; Dougherty, Darin D; Cash, Sydney S; Eskandar, Emad N; Kramer, Mark M; Widge, Alik S (2018). A neural mass model to predict electrical stimulation evoked responses in human and non-human primate brain. Journal of neural engineering, 15 (6) , 066012More Information
Graupe, Daniel; Khobragade, Nivedita; Tuninetti, Daniela; Basu, Ishita; Slavin, Konstantin V; Verhagen Metman, Leo (2018). Who May Benefit From On-Demand Control of Deep Brain Stimulation? Noninvasive Evaluation of Parkinson Patients. Neuromodulation : journal of the International Neuromodulation Society, 21 (6) , 611-616More Information
Widge, Alik S; Ellard, Kristen K; Paulk, Angelique C; Basu, Ishita; Yousefi, Ali; Zorowitz, Samuel; Gilmour, Anna; Afzal, Afsana; Deckersbach, Thilo; Cash, Sydney S; Kramer, Mark A; Eden, Uri T; Dougherty, Darin D; Eskandar, Emad N (2017). Treating refractory mental illness with closed-loop brain stimulation: Progress towards a patient-specific transdiagnostic approach. Experimental neurology, 287 (Pt 4) , 461-472More Information
Basu, Ishita; Kudela, Pawel; Korzeniewska, Anna; Franaszczuk, Piotr J; Anderson, William S (2015). A study of the dynamics of seizure propagation across micro domains in the vicinity of the seizure onset zone. Journal of neural engineering, 12 (4) , 046016More Information
Basu, Ishita; Anderson, William (2014). Bipolar vs monopolar stimulation for cortical mapping: which is better?. Neurosurgery, 75 (4) , N16-7More Information
Graupe, Daniel; Tuninetti, Daniela; Slavin, Konstantin V; Basu, Ishita (2014). Closed-loop electrochemical feedback system for DBS. Journal of neurosurgery, 121 (3) , 762-3More Information
Basu, Ishita; Anderson, William (2014). Bilateral representation of sensory-motor transformations. Neurosurgery, 75 (2) , N15-7More Information
Basu, Ishita; Kudela, Pawel; Anderson, William S (2014). Determination of seizure propagation across microdomains using spectral measures of causality. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2014, 6349-52More Information
Shukla, Pitamber; Basu, Ishita; Tuninetti, Daniela; Graupe, Daniel; Slavin, Konstantin V (2014). On modeling the neuronal activity in movement disorder patients by using the Ornstein Uhlenbeck process. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2014, 2609-12More Information
Shukla, Pitamber; Basu, Ishita; Tuninetti, Daniela (2014). Towards closed-loop deep brain stimulation: decision tree-based essential tremor patient's state classifier and tremor reappearance predictor. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2014, 2605-8More Information
Basu, Ishita; Graupe, Daniel; Tuninetti, Daniela; Shukla, Pitamber; Slavin, Konstantin V; Metman, Leo Verhagen; Corcos, Daniel M (2013). Pathological tremor prediction using surface electromyogram and acceleration: potential use in 'ON-OFF' demand driven deep brain stimulator design. Journal of neural engineering, 10 (3) , 036019More Information
Shukla, Pitamber; Basu, Ishita; Graupe, Daniel; Tuninetti, Daniela; Slavin, Konstantin V (2012). A neural network-based design of an on-off adaptive control for Deep Brain Stimulation in movement disorders. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2012, 4140-3More Information
Basu, Ishita; Tuninetti, Daniela; Graupe, Daniel; Slavin, Konstantin V (2011). Adaptive control of deep brain stimulator for essential tremor: entropy-based tremor prediction using surface-EMG. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2011, 7711-4More Information
Graupe, Daniel; Basu, Ishita; Tuninetti, Daniela; Vannemreddy, Prasad; Slavin, Konstantin V (2010). Adaptively controlling deep brain stimulation in essential tremor patient via surface electromyography. Neurological research, 32 (9) , 899-904More Information
Basu, Ishita; Graupe, Daniel; Tuninetti, Daniela; Slavin, Konstantin V (2010). Stochastic modeling of the neuronal activity in the subthalamic nucleus and model parameter identification from Parkinson patient data. Biological cybernetics, 103 (4) , 273-83More Information
Basu, Ishita; Tuninetti, Daniela; Graupe, Daniel; Slavin, Konstantin V (2010). Stochastic modeling of the neuronal activity in the thalamus of Essential Tremor patient. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2010, 1461-4More Information
Zelmann, Rina; Paulk, Angelique C; Basu, Ishita; Sarma, Anish; Yousefi, Ali; Crocker, Britni; Eskandar, Emad; Williams, Ziv; Cosgrove, G Rees; Weisholtz, Daniel S; Dougherty, Darin D; Truccolo, Wilson; Widge, Alik S; Cash, Sydney S (2020). CLoSES: A platform for closed-loop intracranial stimulation in humans. NeuroImage, 223, 117314More Information
Olsen, Sarah T; Basu, Ishita; Bilge, Mustafa Taha; Kanabar, Anish; Boggess, Matthew J; Rockhill, Alexander P; Gosai, Aishwarya K; Hahn, Emily; Peled, Noam; Ennis, Michaela; Shiff, Ilana; Fairbank-Haynes, Katherine; Salvi, Joshua D; Cusin, Cristina; Deckersbach, Thilo; Williams, Ziv; Baker, Justin T; Dougherty, Darin D; Widge, Alik S (2020). Case Report of Dual-Site Neurostimulation and Chronic Recording of Cortico-Striatal Circuitry in a Patient With Treatment Refractory Obsessive Compulsive Disorder. Frontiers in human neuroscience, 14, 569973More Information
Basu, Ishita; Yousefi, Ali; Crocker, Britni; Zelmann, Rina; Paulk, Angelique C; Peled, Noam; Ellard, Kristen K; Weisholtz, Daniel S; Cosgrove, G Rees; Deckersbach, Thilo; Eden, Uri T; Eskandar, Emad N; Dougherty, Darin D; Cash, Sydney S; Widge, Alik S (2021). Closed-loop enhancement and neural decoding of cognitive control in humans. Nature biomedical engineeringMore Information
Romo-Nava, Francisco; Awosika, Oluwole O; Basu, Ishita; Blom, Thomas J; Welge, Jeffrey; Datta, Abhishek; Guillen, Alexander; Guerdjikova, Anna I; Fleck, David E; Georgiev, Georgi; Mori, Nicole; Patino, Luis R; DelBello, Melissa P; McNamara, Robert K; Buijs, Ruud M; Frye, Mark A; McElroy, Susan L (2023). Effect of non-invasive spinal cord stimulation in unmedicated adults with major depressive disorder: a pilot randomized controlled trial and induced current flow pattern. Molecular psychiatryMore Information
Soper, Daniel J; Reich, Dustine; Ross, Alex; Salami, Pariya; Cash, Sydney S; Basu, Ishita; Peled, Noam; Paulk, Angelique C (2023). Modular pipeline for reconstruction and localization of implanted intracranial ECoG and sEEG electrodes. PloS one, 18 (7) , e0287921More Information
Ross, Alexander; Paulk, Angelique C; Cash, Sydney S; Widge, Alik S; Basu, Ishita (2022). Neural mass model-based study of frontal-temporal theta oscillations in human subjects during the performance of a cognitive control task. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2022, 2937-2940More Information
Agarwal, Shubham; Basu, Ishita; Kumar, Manish; Salami, Pariya; Cash, Sydney S (2022). Classification of Seizure Termination Patterns using Deep Learning on intracranial EEG. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2022, 2933-2936More Information
Widge, Alik S; Ellard, Kristen K; Paulk, Angelique C; Basu, Ishita; Yousefi, Ali; Zorowitz, Samuel; Gilmour, Anna; Afzal, Afsana; Deckersbach, Thilo; Cash, Sydney S; Kramer, Mark A; Eden, Uri T; Dougherty, Darin D; Eskandar, Emad N (2022). Treating Refractory Mental Illness With Closed-Loop Brain Stimulation: Progress Towards a Patient-Specific Transdiagnostic Approach. Focus (American Psychiatric Publishing), 20 (1) , 137-151More Information
Contact Information
Research - University of Cincinnati
231 Albert Sabin Way
Cincinnati
Ohio, 45267
Phone: 513-558-3991
basuia@ucmail.uc.edu