Ishita Basu , PhD

Doctoral Degree: University of Illinois Chicago, IL, 2012 (Electrical engineering)

Postdoctoral Fellowship: John Hopkins University Baltimore, MD, 2014

Research Fellowship: Massachusetts General Hospital Boston, MA, 2016

Research Instructor: Massachusetts General Hospital Boston, MA, 2020

1) Develop data driven and model based approaches for understanding brain rhythms underlying pathological states in patients with neurologic and psychiatric disorders.  
2) Design brain stimulation paradigms for modulating pathologic brain dynamics towards healthy state.

10-2016 -05-2020 Instructor, Harvard Medical School, Boston

Grant: #R21MH127009 Investigators:Basu, Ishita; Shear, Paula; Torres Reveron, Juan 04-01-2022 -03-31-2024 National Institute of Mental Health A neural population model-based characterization and modulation of neural oscillations underlying cognitive control in healthy and depressed/anxious human subjects Role:PI 202500.00 Awarded Level:Federal

Peer Reviewed Publications

Yousefi, Ali; Basu, Ishita; Paulk, Angelique C; Peled, Noam; Eskandar, Emad N; Dougherty, Darin D; Cash, Sydney S; Widge, Alik S; Eden, Uri T (2019. ) Decoding Hidden Cognitive States From Behavior and Physiology Using a Bayesian Approach.Neural computation, , 31 (9 ) ,1751-1788 More Information

Yousefi, Ali; Paulk, Angelique C; Basu, Ishita; Mirsky, Jonathan L; Dougherty, Darin D; Eskandar, Emad N; Eden, Uri T; Widge, Alik S (2018. ) COMPASS: An Open-Source, General-Purpose Software Toolkit for Computational Psychiatry.Frontiers in neuroscience, , 12 ,957 More Information

Basu, Ishita; Robertson, Madeline M; Crocker, Britni; Peled, Noam; Farnes, Kara; Vallejo-Lopez, Deborah I; Deng, Helen; Thombs, Matthew; Martinez-Rubio, Clarissa; Cheng, Jennifer J; McDonald, Eric; Dougherty, Darin D; Eskandar, Emad N; Widge, Alik S; Paulk, Angelique C; Cash, Sydney S Consistent linear and non-linear responses to invasive electrical brain stimulation across individuals and primate species with implanted electrodes.Brain stimulation, , 12 (4 ) ,877-892 More Information

Basu, Ishita; Crocker, Britni; Farnes, Kara; Robertson, Madeline M; Paulk, Angelique C; Vallejo, Deborah I; Dougherty, Darin D; Cash, Sydney S; Eskandar, Emad N; Kramer, Mark M; Widge, Alik S (2018. ) A neural mass model to predict electrical stimulation evoked responses in human and non-human primate brain.Journal of neural engineering, , 15 (6 ) ,066012 More Information

Graupe, Daniel; Khobragade, Nivedita; Tuninetti, Daniela; Basu, Ishita; Slavin, Konstantin V; Verhagen Metman, Leo (2018. ) Who May Benefit From On-Demand Control of Deep Brain Stimulation? Noninvasive Evaluation of Parkinson Patients.Neuromodulation : journal of the International Neuromodulation Society, , 21 (6 ) ,611-616 More Information

Widge, Alik S; Ellard, Kristen K; Paulk, Angelique C; Basu, Ishita; Yousefi, Ali; Zorowitz, Samuel; Gilmour, Anna; Afzal, Afsana; Deckersbach, Thilo; Cash, Sydney S; Kramer, Mark A; Eden, Uri T; Dougherty, Darin D; Eskandar, Emad N (2017. ) Treating refractory mental illness with closed-loop brain stimulation: Progress towards a patient-specific transdiagnostic approach.Experimental neurology, , 287 (Pt 4 ) ,461-472 More Information

Basu, Ishita; Kudela, Pawel; Korzeniewska, Anna; Franaszczuk, Piotr J; Anderson, William S (2015. ) A study of the dynamics of seizure propagation across micro domains in the vicinity of the seizure onset zone.Journal of neural engineering, , 12 (4 ) ,046016 More Information

Basu, Ishita; Anderson, William (2014. ) Bipolar vs monopolar stimulation for cortical mapping: which is better?.Neurosurgery, , 75 (4 ) ,N16-7 More Information

Graupe, Daniel; Tuninetti, Daniela; Slavin, Konstantin V; Basu, Ishita (2014. ) Closed-loop electrochemical feedback system for DBS.Journal of neurosurgery, , 121 (3 ) ,762-3 More Information

Basu, Ishita; Anderson, William (2014. ) Bilateral representation of sensory-motor transformations.Neurosurgery, , 75 (2 ) ,N15-7 More Information

Basu, Ishita; Kudela, Pawel; Anderson, William S (2014. ) Determination of seizure propagation across microdomains using spectral measures of causality.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, , 2014 ,6349-52 More Information

Shukla, Pitamber; Basu, Ishita; Tuninetti, Daniela; Graupe, Daniel; Slavin, Konstantin V (2014. ) On modeling the neuronal activity in movement disorder patients by using the Ornstein Uhlenbeck process.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, , 2014 ,2609-12 More Information

Shukla, Pitamber; Basu, Ishita; Tuninetti, Daniela (2014. ) Towards closed-loop deep brain stimulation: decision tree-based essential tremor patient's state classifier and tremor reappearance predictor.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, , 2014 ,2605-8 More Information

Basu, Ishita; Graupe, Daniel; Tuninetti, Daniela; Shukla, Pitamber; Slavin, Konstantin V; Metman, Leo Verhagen; Corcos, Daniel M (2013. ) Pathological tremor prediction using surface electromyogram and acceleration: potential use in 'ON-OFF' demand driven deep brain stimulator design.Journal of neural engineering, , 10 (3 ) ,036019 More Information

Shukla, Pitamber; Basu, Ishita; Graupe, Daniel; Tuninetti, Daniela; Slavin, Konstantin V (2012. ) A neural network-based design of an on-off adaptive control for Deep Brain Stimulation in movement disorders.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, , 2012 ,4140-3 More Information

Basu, Ishita; Tuninetti, Daniela; Graupe, Daniel; Slavin, Konstantin V (2011. ) Adaptive control of deep brain stimulator for essential tremor: entropy-based tremor prediction using surface-EMG.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, , 2011 ,7711-4 More Information

Graupe, Daniel; Basu, Ishita; Tuninetti, Daniela; Vannemreddy, Prasad; Slavin, Konstantin V (2010. ) Adaptively controlling deep brain stimulation in essential tremor patient via surface electromyography.Neurological research, , 32 (9 ) ,899-904 More Information

Basu, Ishita; Graupe, Daniel; Tuninetti, Daniela; Slavin, Konstantin V (2010. ) Stochastic modeling of the neuronal activity in the subthalamic nucleus and model parameter identification from Parkinson patient data.Biological cybernetics, , 103 (4 ) ,273-83 More Information

Basu, Ishita; Tuninetti, Daniela; Graupe, Daniel; Slavin, Konstantin V (2010. ) Stochastic modeling of the neuronal activity in the thalamus of Essential Tremor patient.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, , 2010 ,1461-4 More Information

Zelmann, Rina; Paulk, Angelique C; Basu, Ishita; Sarma, Anish; Yousefi, Ali; Crocker, Britni; Eskandar, Emad; Williams, Ziv; Cosgrove, G Rees; Weisholtz, Daniel S; Dougherty, Darin D; Truccolo, Wilson; Widge, Alik S; Cash, Sydney S (2020. ) CLoSES: A platform for closed-loop intracranial stimulation in humans.NeuroImage, , 223 ,117314 More Information

Olsen, Sarah T; Basu, Ishita; Bilge, Mustafa Taha; Kanabar, Anish; Boggess, Matthew J; Rockhill, Alexander P; Gosai, Aishwarya K; Hahn, Emily; Peled, Noam; Ennis, Michaela; Shiff, Ilana; Fairbank-Haynes, Katherine; Salvi, Joshua D; Cusin, Cristina; Deckersbach, Thilo; Williams, Ziv; Baker, Justin T; Dougherty, Darin D; Widge, Alik S (2020. ) Case Report of Dual-Site Neurostimulation and Chronic Recording of Cortico-Striatal Circuitry in a Patient With Treatment Refractory Obsessive Compulsive Disorder.Frontiers in human neuroscience, , 14 ,569973 More Information

Basu, Ishita; Yousefi, Ali; Crocker, Britni; Zelmann, Rina; Paulk, Angelique C; Peled, Noam; Ellard, Kristen K; Weisholtz, Daniel S; Cosgrove, G Rees; Deckersbach, Thilo; Eden, Uri T; Eskandar, Emad N; Dougherty, Darin D; Cash, Sydney S; Widge, Alik S (2021. ) Closed-loop enhancement and neural decoding of cognitive control in humans.Nature biomedical engineering, , More Information