
Ishita Basu
Assistant Professor - Research
Medical Sciences Building
5352B
COM Neurosurgery Basu Lab - 0515
Education
PhD, University of Illinois Chicago, 2012 (Electrical engineering)
Positions and Work Experience
10-2016 -05-2020 Instructor, Harvard Medical School, Boston
Research and Practice Interests
1) Develop data driven and model based approaches for understanding brain rhythms underlying pathological states in patients with neurologic and psychiatric disorders.
2) Design brain stimulation paradigms for modulating pathologic brain dynamics towards healthy state.
Publications
Peer Reviewed Publications
Yousefi, Ali; Basu, Ishita; Paulk, Angelique C; Peled, Noam; Eskandar, Emad N; Dougherty, Darin D; Cash, Sydney S; Widge, Alik S; Eden, Uri T (2019. ) Decoding Hidden Cognitive States From Behavior and Physiology Using a Bayesian Approach.Neural computation, , 31 (9 ) ,1751-1788
Yousefi, Ali; Paulk, Angelique C; Basu, Ishita; Mirsky, Jonathan L; Dougherty, Darin D; Eskandar, Emad N; Eden, Uri T; Widge, Alik S (2018. ) COMPASS: An Open-Source, General-Purpose Software Toolkit for Computational Psychiatry.Frontiers in neuroscience, , 12 ,957
Basu, Ishita; Robertson, Madeline M; Crocker, Britni; Peled, Noam; Farnes, Kara; Vallejo-Lopez, Deborah I; Deng, Helen; Thombs, Matthew; Martinez-Rubio, Clarissa; Cheng, Jennifer J; McDonald, Eric; Dougherty, Darin D; Eskandar, Emad N; Widge, Alik S; Paulk, Angelique C; Cash, Sydney S Consistent linear and non-linear responses to invasive electrical brain stimulation across individuals and primate species with implanted electrodes.Brain stimulation, , 12 (4 ) ,877-892
Basu, Ishita; Crocker, Britni; Farnes, Kara; Robertson, Madeline M; Paulk, Angelique C; Vallejo, Deborah I; Dougherty, Darin D; Cash, Sydney S; Eskandar, Emad N; Kramer, Mark M; Widge, Alik S (2018. ) A neural mass model to predict electrical stimulation evoked responses in human and non-human primate brain.Journal of neural engineering, , 15 (6 ) ,066012
Graupe, Daniel; Khobragade, Nivedita; Tuninetti, Daniela; Basu, Ishita; Slavin, Konstantin V; Verhagen Metman, Leo (2018. ) Who May Benefit From On-Demand Control of Deep Brain Stimulation? Noninvasive Evaluation of Parkinson Patients.Neuromodulation : journal of the International Neuromodulation Society, , 21 (6 ) ,611-616
Widge, Alik S; Ellard, Kristen K; Paulk, Angelique C; Basu, Ishita; Yousefi, Ali; Zorowitz, Samuel; Gilmour, Anna; Afzal, Afsana; Deckersbach, Thilo; Cash, Sydney S; Kramer, Mark A; Eden, Uri T; Dougherty, Darin D; Eskandar, Emad N (2017. ) Treating refractory mental illness with closed-loop brain stimulation: Progress towards a patient-specific transdiagnostic approach.Experimental neurology, , 287 (Pt 4 ) ,461-472
Basu, Ishita; Kudela, Pawel; Korzeniewska, Anna; Franaszczuk, Piotr J; Anderson, William S (2015. ) A study of the dynamics of seizure propagation across micro domains in the vicinity of the seizure onset zone.Journal of neural engineering, , 12 (4 ) ,046016
Basu, Ishita; Anderson, William (2014. ) Bipolar vs monopolar stimulation for cortical mapping: which is better?.Neurosurgery, , 75 (4 ) ,N16-7
Graupe, Daniel; Tuninetti, Daniela; Slavin, Konstantin V; Basu, Ishita (2014. ) Closed-loop electrochemical feedback system for DBS.Journal of neurosurgery, , 121 (3 ) ,762-3
Basu, Ishita; Anderson, William (2014. ) Bilateral representation of sensory-motor transformations.Neurosurgery, , 75 (2 ) ,N15-7
Basu, Ishita; Kudela, Pawel; Anderson, William S (2014. ) Determination of seizure propagation across microdomains using spectral measures of causality.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, , 2014 ,6349-52
Shukla, Pitamber; Basu, Ishita; Tuninetti, Daniela; Graupe, Daniel; Slavin, Konstantin V (2014. ) On modeling the neuronal activity in movement disorder patients by using the Ornstein Uhlenbeck process.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, , 2014 ,2609-12
Shukla, Pitamber; Basu, Ishita; Tuninetti, Daniela (2014. ) Towards closed-loop deep brain stimulation: decision tree-based essential tremor patient's state classifier and tremor reappearance predictor.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, , 2014 ,2605-8
Basu, Ishita; Graupe, Daniel; Tuninetti, Daniela; Shukla, Pitamber; Slavin, Konstantin V; Metman, Leo Verhagen; Corcos, Daniel M (2013. ) Pathological tremor prediction using surface electromyogram and acceleration: potential use in 'ON-OFF' demand driven deep brain stimulator design.Journal of neural engineering, , 10 (3 ) ,036019
Shukla, Pitamber; Basu, Ishita; Graupe, Daniel; Tuninetti, Daniela; Slavin, Konstantin V (2012. ) A neural network-based design of an on-off adaptive control for Deep Brain Stimulation in movement disorders.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, , 2012 ,4140-3
Basu, Ishita; Tuninetti, Daniela; Graupe, Daniel; Slavin, Konstantin V (2011. ) Adaptive control of deep brain stimulator for essential tremor: entropy-based tremor prediction using surface-EMG.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, , 2011 ,7711-4
Graupe, Daniel; Basu, Ishita; Tuninetti, Daniela; Vannemreddy, Prasad; Slavin, Konstantin V (2010. ) Adaptively controlling deep brain stimulation in essential tremor patient via surface electromyography.Neurological research, , 32 (9 ) ,899-904
Basu, Ishita; Graupe, Daniel; Tuninetti, Daniela; Slavin, Konstantin V (2010. ) Stochastic modeling of the neuronal activity in the subthalamic nucleus and model parameter identification from Parkinson patient data.Biological cybernetics, , 103 (4 ) ,273-83
Basu, Ishita; Tuninetti, Daniela; Graupe, Daniel; Slavin, Konstantin V (2010. ) Stochastic modeling of the neuronal activity in the thalamus of Essential Tremor patient.Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, , 2010 ,1461-4
Zelmann, Rina; Paulk, Angelique C; Basu, Ishita; Sarma, Anish; Yousefi, Ali; Crocker, Britni; Eskandar, Emad; Williams, Ziv; Cosgrove, G Rees; Weisholtz, Daniel S; Dougherty, Darin D; Truccolo, Wilson; Widge, Alik S; Cash, Sydney S (2020. ) CLoSES: A platform for closed-loop intracranial stimulation in humans.NeuroImage, , 223 ,117314
Olsen, Sarah T; Basu, Ishita; Bilge, Mustafa Taha; Kanabar, Anish; Boggess, Matthew J; Rockhill, Alexander P; Gosai, Aishwarya K; Hahn, Emily; Peled, Noam; Ennis, Michaela; Shiff, Ilana; Fairbank-Haynes, Katherine; Salvi, Joshua D; Cusin, Cristina; Deckersbach, Thilo; Williams, Ziv; Baker, Justin T; Dougherty, Darin D; Widge, Alik S (2020. ) Case Report of Dual-Site Neurostimulation and Chronic Recording of Cortico-Striatal Circuitry in a Patient With Treatment Refractory Obsessive Compulsive Disorder.Frontiers in human neuroscience, , 14 ,569973
Post Graduate Training and Education
2012-2014 Postdoctoral fellow, Johns Hopkins University, , Baltimore
2015-2016 Research fellow, Massachusetts General Hospital, , Boston
2017-2020 Research Instructor, Massachusetts General Hospital, , Boston