Temugin Berta, PhD

Doctoral Degree: University of Lausanne 2008

Post-Doctoral Fellowship: Harvard University 2009

Post-Doctoral Fellowship: Duke University 2012

Grant: #R21 NS100469 Investigators:Baccei, Mark; Berta, Temugin; Seroogy, Kim 06-01-2017 -05-30-2019 National Institute of Neurological Disorders and Stroke Identification of novel analgesic targets in ascending spinal projection neurons Role:Collaborator $199,062.00

Grant: #R21NS106264 Investigators:Berta, Temugin; Davidson, Steve 09-01-2018 -08-31-2020 National Institute of Neurological Disorders and Stroke Purification and Characterization of Mature Murine and Human Satellite Glial Cells Role:PI $240,128.00 Active Level:Federal

Grant: #R01NS113243 Investigators:Berta, Temugin; Strong, Judith; Xie, Wen-Rui; Zhang, Jun-Ming 07-01-2019 -05-31-2024 National Institute of Neurological Disorders and Stroke Targeting sensory ganglia and glial signaling for the treatment of acute and chronic pain Role:PI $2,006,250.00 Awarded Level:Federal

Grant: #Discovery Grant Investigators:Berta, Temugin 08-01-2019 -07-31-2020 National Psoriasis Foundation TRANSIENT RECEPTOR POTENTIAL CHANNEL 4 AS A NOVEL TARGET TO RELIEVE PSORIASIS Role:PI $75,000.00 Awarded Level:Private Non-Profit

Grant: #R21NS121946 Investigators:Berta, Temugin 04-15-2021 -10-14-2022 National Institute of Neurological Disorders and Stroke STING & PAIN: exploring a viral signaling protein in nociception and neuropathy Role:PI $445,031.00 Awarded Level:Federal

Investigators:Berta, Temugin; Strong, Judith; Xie, Wen-Rui; Zhang, Jun-Ming 07-15-2021 -06-30-2026 National Institute of Neurological Disorders and Stroke Study of Activity-Dependent Sympathetic Sprouting" Role:Collaborator 0.00 Awarded Level:Federal

Grant: #R21NS130138 Investigators:Berta, Temugin; Davidson, Steve; Supp, Dorothy 09-08-2022 -08-31-2024 National Institute of Neurological Disorders and Stroke Genetic and physiological comparison of native human sensory neurons and induced pluripotent stem cells differentiated to sensory neurons Role:Collaborator 445500.00 Awarded Level:Federal

Grant: #R01NS136108 Investigators:Berta, Temugin; Davidson, Steve; Lee, Sanghoon; Xie, Wen-Rui; Zhang, Jun-Ming 04-01-2024 -03-31-2029 National Institute of Neurological Disorders and Stroke Cellular Mechanisms and Therapeutic Potential of NR4A1 in Pain Resolution Role:PI 0.00 Hold Level:Federal

Investigators:Berta, Temugin; Strong, Judith; Xie, Wen-Rui; Zhang, Jun-Ming 07-01-2024 -06-30-2029 National Institute of Neurological Disorders and Stroke Neuron vasculature interactions in pain Role:Collaborator 0.00 Hold Level:Federal

Grant: #303002948; RF1-NS131812 Investigators:Berta, Temugin 09-01-2025 -08-31-2026 National Institute of Neurological Disorders and Stroke Targeting checkpoint inhibitors for pain control Role:PI 91169.00 Hold Level:Federal

Peer Reviewed Publications

Lee, Sang Hoon; Cho, Pyung Sun; Tonello, Raquel; Lee, Han Kyu; Jang, Jun Ho; Park, Gi Yeon; Hwang, Sun Wook; Park, Chul-Kyu; Jung, Sung Jun; Berta, Temugin  (2018). Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice. The Journal of allergy and clinical immunologyMore Information

Chamessian, Alexander; Young, Michael; Qadri, Yawar; Berta, Temugin; Ji, Ru-Rong; Van de Ven, Thomas  (2018). Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn. Scientific reports, 8 (1) , 6809More Information

Chang, Wonseok; Berta, Temugin; Kim, Yong Ho; Lee, Sanghoon; Lee, Seok-Yong; Ji, Ru-Rong  (2018). Expression and Role of Voltage-Gated Sodium Channels in Human Dorsal Root Ganglion Neurons with Special Focus on Nav1.7, Species Differences, and Regulation by Paclitaxel. Neuroscience bulletin, 34 (1) , 4-12More Information

Berta, Temugin; Perrin, Florence E; Pertin, Marie; Tonello, Raquel; Liu, Yen-Chin; Chamessian, Alexander; Kato, Ann C; Ji, Ru-Rong; Decosterd, Isabelle  (2017). Gene Expression Profiling of Cutaneous Injured and Non-Injured Nociceptors in SNI Animal Model of Neuropathic Pain. Scientific reports, 7 (1) , 9367More Information

Berta, Temugin; Qadri, Yawar; Tan, Ping-Heng; Ji, Ru-Rong  (2017). Targeting dorsal root ganglia and primary sensory neurons for the treatment of chronic pain. Expert opinion on therapeutic targets, 21 (7) , 695-703More Information

Xu, Zhen-Zhong; Kim, Yong Ho; Bang, Sangsu; Zhang, Yi; Berta, Temugin; Wang, Fan; Oh, Seog Bae; Ji, Ru-Rong  (2015). Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade. Nature medicine, 21 (11) , 1326-31More Information

McKelvey, Rebecca; Berta, Temugin; Old, Elizabeth; Ji, Ru-Rong; Fitzgerald, Maria  (2015). Neuropathic pain is constitutively suppressed in early life by anti-inflammatory neuroimmune regulation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 35 (2) , 457-66More Information

Liu, Xing-Jun; Zhang, Yanli; Liu, Tong; Xu, Zhen-Zhong; Park, Chul-Kyu; Berta, Temugin; Jiang, Dianhua; Ji, Ru-Rong  (2014). Nociceptive neurons regulate innate and adaptive immunity and neuropathic pain through MyD88 adapter. Cell research, 24 (11) , 1374-7More Information

Park, Chul-Kyu; Xu, Zhen-Zhong; Berta, Temugin; Han, Qingjian; Chen, Gang; Liu, Xing-Jun; Ji, Ru-Rong  (2014). Extracellular microRNAs activate nociceptor neurons to elicit pain via TLR7 and TRPA1. Neuron, 82 (1) , 47-54More Information

Berta, Temugin; Park, Chul-Kyu; Xu, Zhen-Zhong; Xie, Ruo-Gang; Liu, Tong; Lü, Ning; Liu, Yen-Chin; Ji, Ru-Rong  (2014). Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-? secretion. The Journal of clinical investigation, 124 (3) , 1173-86More Information

Ji, Ru-Rong; Berta, Temugin; Nedergaard, Maiken  (2013). Glia and pain: is chronic pain a gliopathy?. Pain, 154 Suppl 1, S10-28More Information

Liu, Tong; Berta, Temugin; Xu, Zhen-Zhong; Park, Chul-Kyu; Zhang, Ling; Lü, Ning; Liu, Qin; Liu, Yang; Gao, Yong-Jing; Liu, Yen-Chin; Ma, Qiufu; Dong, Xinzhong; Ji, Ru-Rong  (2012). TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice. The Journal of clinical investigation, 122 (6) , 2195-207More Information

Xu, Zhen-Zhong; Zhang, Ling; Liu, Tong; Park, Jong Yeon; Berta, Temugin; Yang, Rong; Serhan, Charles N; Ji, Ru-Rong  (2010). Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions. Nature medicine, 16 (5) , 592-7, 1p following More Information

Tonello, Raquel; Xie, Wenrui; Lee, Sang Hoon; Wang, Min; Liu, Xiaojuan; Strong, Judith A; Zhang, Jun-Ming; Berta, Temugin  (2020). Local Sympathectomy Promotes Antiinflammatory Responses and Relief of Paclitaxel-induced Mechanical and Cold Allodynia in Mice. AnesthesiologyMore Information

Gattlen, Christophe; Deftu, Alexandru-Florian; Tonello, Raquel; Ling, Yuejuan; Berta, Temugin; Ristoiu, Violeta; Suter, Marc René  (2020). The inhibition of Kir2.1 potassium channels depolarizes spinal microglial cells, reduces their proliferation, and attenuates neuropathic pain. GliaMore Information

Liu, Xiaojuan; Tonello, Raquel; Ling, Yuejuan; Gao, Yong-Jing; Berta, Temugin  (2019). Paclitaxel-activated astrocytes produce mechanical allodynia in mice by releasing tumor necrosis factor-? and stromal-derived cell factor 1. Journal of neuroinflammation, 16 (1) , 209More Information

Serafin, Elizabeth K; Chamessian, Alexander; Li, Jie; Zhang, Xiang; McGann, Amanda; Brewer, Chelsie L; Berta, Temugin; Baccei, Mark  (2019). Transcriptional profile of spinal dynorphin-lineage interneurons in the developing mouse. Pain, 160 (10) , 2380-2397More Information

Tonello, Raquel; Lee, Sang Hoon; Berta, Temugin  (2019). Monoclonal Antibody Targeting the Matrix Metalloproteinase 9 Prevents and Reverses Paclitaxel-Induced Peripheral Neuropathy in Mice. The journal of pain : official journal of the American Pain Society, 20 (5) , 515-527More Information

Ibrahim, Shaimaa I A; Xie, Wenrui; Strong, Judith A; Tonello, Raquel; Berta, Temugin; Zhang, Jun-Ming  (2018). Mineralocorticoid Antagonist Improves Glucocorticoid Receptor Signaling and Dexamethasone Analgesia in an Animal Model of Low Back Pain. Frontiers in cellular neuroscience, 12, 453More Information

Song, Zongbin; Xie, Wenrui; Strong, Judith A; Berta, Temugin; Ulrich-Lai, Yvonne M; Guo, Qulian; Zhang, Jun-Ming  (2018). High-fat diet exacerbates postoperative pain and inflammation in a sex-dependent manner. Pain, 159 (9) , 1731-1741More Information

Priebe, Alaini; Hunke, Megan; Tonello, Raquel; Sonawane, Yogesh; Berta, Temugin; Natarajan, Amarnath; Bhuvanesh, Nattamai; Pattabiraman, Mahesh; Chandra, Surabhi  (2018). Ferulic acid dimer as a non-opioid therapeutic for acute pain. Journal of pain research, 11, 1075-1085More Information

Chen, Gang; Luo, Xin; Qadri, M Yawar; Berta, Temugin; Ji, Ru-Rong  (2018). Sex-Dependent Glial Signaling in Pathological Pain: Distinct Roles of Spinal Microglia and Astrocytes. Neuroscience bulletin, 34 (1) , 98-108More Information

Chamessian, Alexander G; Qadri, Yawar J; Cummins, Matthew; Hendrickson, Michele; Berta, Temugin; Buchheit, Thomas; Van de Ven, Thomas  (2017). 5-Hydroxymethylcytosine (5hmC) and Ten-eleven translocation 1-3 (TET1-3) proteins in the dorsal root ganglia of mouse: Expression and dynamic regulation in neuropathic pain. Somatosensory & motor research, 34 (2) , 72-79More Information

Berta, Temugin; Lee, Jee Eun; Park, Chul-Kyu  (2017). Unconventional Role of Caspase-6 in Spinal Microglia Activation and Chronic Pain. Mediators of inflammation, 2017, 9383184More Information

Han, Qingjian; Kim, Yong Ho; Wang, Xiaoming; Liu, Di; Zhang, Zhi-Jun; Bey, Alexandra L; Lay, Mark; Chang, Wonseok; Berta, Temugin; Zhang, Yan; Jiang, Yong-Hui; Ji, Ru-Rong  (2016). SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons. Neuron, 92 (6) , 1279-1293More Information

Liu, Chien-Cheng; Gao, Yong-Jing; Luo, Hao; Berta, Temugin; Xu, Zhen-Zhong; Ji, Ru-Rong; Tan, Ping-Heng  (2016). Interferon alpha inhibits spinal cord synaptic and nociceptive transmission via neuronal-glial interactions. Scientific reports, 6, 34356More Information

Berta, T; Qadri, Y J; Chen, G; Ji, R R  (2016). Microglial Signaling in Chronic Pain with a Special Focus on Caspase 6, p38 MAP Kinase, and Sex Dependence. Journal of dental research, 95 (10) , 1124-31More Information

Chen, Gang; Xie, Rou-Gang; Gao, Yong-Jing; Xu, Zhen-Zhong; Zhao, Lin-Xia; Bang, Sangsu; Berta, Temugin; Park, Chul-Kyu; Lay, Mark; Chen, Wei; Ji, Ru-Rong  (2016). ?-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain. Nature communications, 7, 12531More Information

Taves, Sarah; Berta, Temugin; Liu, Da-Lu; Gan, Sophie; Chen, Gang; Kim, Yong Ho; Van de Ven, Thomas; Laufer, Stefan; Ji, Ru-Rong  (2016). Spinal inhibition of p38 MAP kinase reduces inflammatory and neuropathic pain in male but not female mice: Sex-dependent microglial signaling in the spinal cord. Brain, behavior, and immunity, 55, 70-81More Information

Martini, Alessandra Cadete; Berta, Temugin; Forner, Stefânia; Chen, Gang; Bento, Allisson Freire; Ji, Ru-Rong; Rae, Giles Alexander  (2016). Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection. Journal of neuroinflammation, 13 (1) , 75More Information

Liu, Tong; Han, Qingjian; Chen, Gang; Huang, Ya; Zhao, Lin-Xia; Berta, Temugin; Gao, Yong-Jing; Ji, Ru-Rong  (2016). Toll-like receptor 4 contributes to chronic itch, alloknesis, and spinal astrocyte activation in male mice. Pain, 157 (4) , 806-17More Information

Jiang, Bao-Chun; Cao, De-Li; Zhang, Xin; Zhang, Zhi-Jun; He, Li-Na; Li, Chun-Hua; Zhang, Wen-Wen; Wu, Xiao-Bo; Berta, Temugin; Ji, Ru-Rong; Gao, Yong-Jing  (2016). CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5. The Journal of clinical investigation, 126 (2) , 745-61More Information

Soens, Mieke; Wang, Jeffrey C-F; Berta, Temugin; Strichartz, Gary  (2015). Systemic Progesterone Administration in Early Life Alters the Hyperalgesic Responses to Surgery in the Adult: A Study on Female Rats. Anesthesia and analgesia, 121 (2) , 545-55More Information

Chen, Gang; Park, Chul-Kyu; Xie, Rou-Gang; Berta, Temugin; Nedergaard, Maiken; Ji, Ru-Rong  (2014). Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice. Brain : a journal of neurology, 137 (Pt 8) , 2193-209More Information

Berta, T; Liu, Y-C; Xu, Z-Z; Ji, R-R  (2013). Tissue plasminogen activator contributes to morphine tolerance and induces mechanical allodynia via astrocytic IL-1? and ERK signaling in the spinal cord of mice. Neuroscience, 247, 376-85More Information

Xu, Zhen-Zhong; Liu, Xing-Jun; Berta, Temugin; Park, Chul-Kyu; Lü, Ning; Serhan, Charles N; Ji, Ru-Rong  (2013). Neuroprotectin/protectin D1 protects against neuropathic pain in mice after nerve trauma. Annals of neurology, 74 (3) , 490-5More Information

Xu, Zhen-Zhong; Berta, Temugin; Ji, Ru-Rong  (2013). Resolvin E1 inhibits neuropathic pain and spinal cord microglial activation following peripheral nerve injury. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 8 (1) , 37-41More Information

Taves, Sarah; Berta, Temugin; Chen, Gang; Ji, Ru-Rong  (2013). Microglia and spinal cord synaptic plasticity in persistent pain. Neural plasticity, 2013, 753656More Information

Tan, P H; Gao, Y J; Berta, T; Xu, Z Z; Ji, R R  (2012). Short small-interfering RNAs produce interferon-?-mediated analgesia. British journal of anaesthesia, 108 (4) , 662-9More Information

Liu, Yen-Chin; Berta, Temugin; Liu, Tong; Tan, Ping-Heng; Ji, Ru-Rong  (2012). Acute morphine induces matrix metalloproteinase-9 up-regulation in primary sensory neurons to mask opioid-induced analgesia in mice. Molecular pain, 8, 19More Information

Berta, Temugin; Liu, Tong; Liu, Yen-Chin; Xu, Zhen-Zhong; Ji, Ru-Rong  (2012). Acute morphine activates satellite glial cells and up-regulates IL-1? in dorsal root ganglia in mice via matrix metalloprotease-9. Molecular pain, 8, 18More Information

Zhang, Ling; Berta, Temugin; Xu, Zhen-Zhong; Liu, Tong; Park, Jong Yeon; Ji, Ru-Rong  (2011). TNF-? contributes to spinal cord synaptic plasticity and inflammatory pain: distinct role of TNF receptor subtypes 1 and 2. Pain, 152 (2) , 419-27More Information

Liu, Tong; Xu, Zhen-Zhong; Park, Chul-Kyu; Berta, Temugin; Ji, Ru-Rong  (2010). Toll-like receptor 7 mediates pruritus. Nature neuroscience, 13 (12) , 1460-2More Information

Suter, Marc R; Berta, Temugin; Gao, Yong-Jing; Decosterd, Isabelle; Ji, Ru-Rong  (2009). Large A-fiber activity is required for microglial proliferation and p38 MAPK activation in the spinal cord: different effects of resiniferatoxin and bupivacaine on spinal microglial changes after spared nerve injury. Molecular pain, 5, 53More Information

Berta, Temugin; Poirot, Olivier; Pertin, Marie; Ji, Ru-Rong; Kellenberger, Stephan; Decosterd, Isabelle  (2008). Transcriptional and functional profiles of voltage-gated Na(+) channels in injured and non-injured DRG neurons in the SNI model of neuropathic pain. Molecular and cellular neurosciences, 37 (2) , 196-208More Information

Poirot, Olivier; Berta, Temugin; Decosterd, Isabelle; Kellenberger, Stephan  (2006). Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury. The Journal of physiology, 576 (Pt 1) , 215-34More Information

Pertin, Marie; Ji, Ru-Rong; Berta, Temugin; Powell, Andrew J; Karchewski, Laurie; Tate, Simon N; Isom, Lori L; Woolf, Clifford J; Gilliard, Nicolas; Spahn, Donat R; Decosterd, Isabelle  (2005). Upregulation of the voltage-gated sodium channel beta2 subunit in neuropathic pain models: characterization of expression in injured and non-injured primary sensory neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 25 (47) , 10970-80More Information

Girard, P; Porte, L; Berta, T; Jordan, M; Wurm, F M  (2001). Calcium phosphate transfection optimization for serum-free suspension culture. Cytotechnology, 35 (3) , 175-80More Information

Zhang, Li; Xie, Wenrui; Zhang, Jingdong; Shanahan, Hailey; Tonello, Raquel; Lee, Sang Hoon; Strong, Judith A; Berta, Temugin; Zhang, Jun-Ming  (2021). Key role of CCR2-expressing macrophages in a mouse model of low back pain and radiculopathy. Brain, behavior, and immunity, 91, 556-567More Information

Lee, Sang Hoon; Tonello, Raquel; Choi, Youngin; Jung, Sung Jun; Berta, Temugin  (2020). Sensory Neuron-Expressed TRPC4 Is a Target for the Relief of Psoriasiform Itch and Skin Inflammation in Mice. The Journal of investigative dermatology, 140 (11) , 2221-2229.e6More Information

Lee, Sang Hoon; Tonello, Raquel; Im, Sang-Taek; Jeon, Hawon; Park, Jeongsu; Ford, Zachary; Davidson, Steve; Kim, Yong Ho; Park, Chul-Kyu; Berta, Temugin  (2020). Resolvin D3 controls mouse and human TRPV1-positive neurons and preclinical progression of psoriasis. Theranostics, 10 (26) , 12111-12126More Information

Tonello, Raquel; Xie, Wenrui; Lee, Sang Hoon; Wang, Min; Liu, Xiaojuan; Strong, Judith A; Zhang, Jun-Ming; Berta, Temugin  (2020). Local Sympathectomy Promotes Anti-inflammatory Responses and Relief of Paclitaxel-induced Mechanical and Cold Allodynia in Mice. Anesthesiology, 132 (6) , 1540-1553More Information

Luo, Xin; Chen, Ouyang; Wang, Zilong; Bang, Sangsu; Ji, Jasmine; Lee, Sang Hoon; Huh, Yul; Furutani, Kenta; He, Qianru; Tao, Xueshu; Ko, Mei-Chuan; Bortsov, Andrey; Donnelly, Christopher R; Chen, Yong; Nackley, Andrea; Berta, Temugin; Ji, Ru-Rong  (2021). IL-23/IL-17A/TRPV1 axis produces mechanical pain via macrophage-sensory neuron crosstalk in female mice. Neuron, 109 (17) , 2691-2706.e5More Information

Xie, Wenrui; Lückemeyer, Debora Denardin; Qualls, Katherine A; Prudente, Arthur Silveira; Berta, Temugin; Gu, Mingxia; Strong, Judith A; Dong, Xinzhong; Zhang, Jun-Ming  (2025). Vascular motion in the dorsal root ganglion sensed by Piezo2 in sensory neurons triggers episodic neuropathic pain. NeuronMore Information

Hwang, Sung-Min; Roh, Jueun; Go, Eun Jin; Pan, Jing-Ying; Park, Jaeik; Rahman, Mahbubur; Jung, YunJae; Lee, Sun-Ho; Han, Inbo; Chung, Gehoon; Lee, Sang Hoon; Berta, Temugin; Park, Chul-Kyu; Kim, Yong Ho  (2025). The LRP1-SHP2 pathway regulates TRPV1 sensitivity in the peripheral nervous system: Insights from amyloid beta 1-42 modulation. Journal of advanced researchMore Information

Hwang, Sung-Min; Rahman, Md Mahbubur; Go, Eun Jin; Roh, Jueun; Park, Rayoung; Lee, Sung-Gwon; Nahm, Minyeop; Berta, Temugin; Kim, Yong Ho; Park, Chul-Kyu  (2025). Modulation of pain sensitivity by Ascl1- and Lhx6-dependent GABAergic neuronal function in streptozotocin diabetic mice. Molecular therapy : the journal of the American Society of Gene Therapy, 33 (2) , 786-804More Information

Lee, Sang Hoon; Tonello, Raquel; Lee, Kihwan; Roh, Jueun; Prudente, Arthur Silveira; Kim, Yong Ho; Park, Chul-Kyu; Berta, Temugin  (2024). The Parkinson's disease DJ-1/PARK7 gene controls peripheral neuronal excitability and painful neuropathy. Brain : a journal of neurologyMore Information

Go, Eun Jin; Hwang, Sung-Min; Jo, Hyunjung; Rahman, Md Mahbubur; Park, Jaeik; Lee, Ji Yeon; Jo, Youn Yi; Lee, Byung-Gil; Jung, YunJae; Berta, Temugin; Kim, Yong Ho; Park, Chul-Kyu  (2024). GLP-1 and its derived peptides mediate pain relief through direct TRPV1 inhibition without affecting thermoregulation. Experimental & molecular medicine, 56 (11) , 2449-2464More Information

Lee, Sang Hoon; Bonifacio, Fabio; Prudente, Arthur Silveira; Choi, Y I; Roh, Jueun; Adjafre, Beatriz Lima; Park, Chul-Kyu; Jung, Sung Jun; Cunha, Thiago M; Berta, Temugin  (2024). STING recognition of viral dsDNA by nociceptors mediates pain in mice. Brain, behavior, and immunity, 121, 29-42More Information

Chen, Ouyang; Jiang, Changyu; Berta, Temugin; Powell Gray, Bethany; Furutani, Kenta; Sullenger, Bruce A; Ji, Ru-Rong  (2024). MicroRNA let-7b enhances spinal cord nociceptive synaptic transmission and induces acute and persistent pain through neuronal and microglial signaling. Pain, 165 (8) , 1824-1839More Information

Li, Xinmeng; Prudente, Arthur Silveira; Prato, Vincenzo; Guo, Xianchuan; Hao, Han; Jones, Frederick; Figoli, Sofia; Mullen, Pierce; Wang, Yujin; Tonello, Raquel; Lee, Sang Hoon; Shah, Shihab; Maffei, Benito; Berta, Temugin; Du, Xiaona; Gamper, Nikita  (2024). Peripheral gating of mechanosensation by glial diazepam binding inhibitor. The Journal of clinical investigation, 134 (16) More Information

Park, Chul-Kyu; Go, Eun Jin; Jo, Hyunjung; Hwang, Sung-Min; Rahman, Md Mahbubur; Park, Jaeik; Lee, Ji Yeon; Jo, Youn Yi; Jung, YunJae; Berta, Temugin; Kim, Yong Ho  (2024). GLP-1 and Its Derived Peptides Mediate Pain Relief Through Direct TRPV1 Inhibition Without Affecting Thermoregulation. Research squareMore Information

Bang, Sangsu; Jiang, Changyu; Xu, Jing; Chandra, Sharat; McGinnis, Aidan; Luo, Xin; He, Qianru; Li, Yize; Wang, Zilong; Ao, Xiang; Parisien, Marc; Fernandes de Araujo, Lorenna Oliveira; Jahangiri Esfahani, Sahel; Zhang, Qin; Tonello, Raquel; Berta, Temugin; Diatchenko, Luda; Ji, Ru-Rong  (2024). Satellite glial GPR37L1 and its ligand maresin 1 regulate potassium channel signaling and pain homeostasis. The Journal of clinical investigation, 134 (9) More Information

Silveira Prudente, Arthur; Hoon Lee, Sang; Roh, Jueun; Luckemeyer, Debora D; Cohen, Cinder F; Pertin, Marie; Park, Chul-Kyu; Suter, Marc R; Decosterd, Isabelle; Zhang, Jun-Ming; Ji, Ru-Rong; Berta, Temugin  (2024). Microglial STING activation alleviates nerve injury-induced neuropathic pain in male but not female mice. Brain, behavior, and immunity, 117, 51-65More Information

Tonello, Raquel; Davidson, Steve; Berta, Temugin  (2023). Dissociation and Culture of Adult Mouse Satellite Glial Cells. Bio-protocol, 13 (24) , e4906More Information

Bang, Sangsu; Jiang, Changyu; Xu, Jing; Chandra, Sharat; McGinnis, Aidan; Luo, Xin; He, Qianru; Li, Yize; Wang, Zilong; Ao, Xiang; Parisien, Marc; Fernandes de Araujo, Lorenna Oliveira; Esfahan, Sahel Jahangiri; Zhang, Qin; Tonello, Raquel; Berta, Temugin; Diatchenko, Luda; Ji, Ru-Rong  (2023). Satellite glial GPR37L1 regulates maresin and potassium channel signaling for pain control. bioRxiv : the preprint server for biologyMore Information

Li, Xinmeng; Prudente, Arthur Silveira; Prato, Vincenzo; Guo, Xianchuan; Hao, Han; Jones, Frederick; Figoli, Sofia; Mullen, Pierce; Wang, Yujin; Tonnello, Raquel; Lee, Sang Hoon; Shah, Shihab; Maffei, Benito; Berta, Temugin; Du, Xiaona; Gamper, Nikita  (2023). Peripheral gating of pain by glial endozepine. bioRxiv : the preprint server for biologyMore Information

Tonello, Raquel; Silveira Prudente, Arthur; Hoon Lee, Sang; Faith Cohen, Cinder; Xie, Wenrui; Paranjpe, Aditi; Roh, Jueun; Park, Chul-Kyu; Chung, Gehoon; Strong, Judith A; Zhang, Jun-Ming; Berta, Temugin  (2023). Single-cell analysis of dorsal root ganglia reveals metalloproteinase signaling in satellite glial cells and pain. Brain, behavior, and immunity, 113, 401-414More Information

Lückemeyer, Debora Denardin; Xie, Wenrui; Prudente, Arthur Silveira; Qualls, Katherine A; Tonello, Raquel; Strong, Judith A; Berta, Temugin; Zhang, Jun-Ming  (2023). The Antinociceptive Effect of Sympathetic Block is Mediated by Transforming Growth Factor β in a Mouse Model of Radiculopathy. Neuroscience bulletin, 39 (9) , 1363-1374More Information

Berta, Temugin; Strong, Judith A; Zhang, Jun-Ming; Ji, Ru-Rong  (2023). Targeting dorsal root ganglia and primary sensory neurons for the treatment of chronic pain: an update. Expert opinion on therapeutic targets, 27 (8) , 665-678More Information

Cohen, Cinder Faith; Roh, Jueun; Lee, Sang Hoon; Park, Chul-Kyu; Berta, Temugin  (2023). Targeting Nociceptive Neurons and Transient Receptor Potential Channels for the Treatment of Migraine. International journal of molecular sciences, 24 (9) More Information

Lei, Beilei; Ho Kim, Yong; Qi, Wenjing; Berta, Temugin; Covington, Anna; Lusk, Jay B; Warner, David S; Ji, Ru-Rong; James, Michael L  (2022). In vivo single microglial cell isolation after intracerebral hemorrhage in mice. Neuroscience letters, 787, 136822More Information

Hwang, Sung-Min; Jo, Youn-Yi; Cohen, Cinder Faith; Kim, Yong-Ho; Berta, Temugin; Park, Chul-Kyu  (2022). Venom Peptide Toxins Targeting the Outer Pore Region of Transient Receptor Potential Vanilloid 1 in Pain: Implications for Analgesic Drug Development. International journal of molecular sciences, 23 (10) More Information

Iwasawa, Eri; Brown, Farrah N; Shula, Crystal; Kahn, Fatima; Lee, Sang Hoon; Berta, Temugin; Ladle, David R; Campbell, Kenneth; Mangano, Francesco T; Goto, June  (2022). The Anti-Inflammatory Agent Bindarit Attenuates the Impairment of Neural Development through Suppression of Microglial Activation in a Neonatal Hydrocephalus Mouse Model. The Journal of neuroscience : the official journal of the Society for Neuroscience, 42 (9) , 1820-1844More Information

Cohen, Cinder Faith; Prudente, Arthur Silveira; Berta, Temugin; Lee, Sang Hoon  (2021). Transient Receptor Potential Channel 4 Small-Molecule Inhibition Alleviates Migraine-Like Behavior in Mice. Frontiers in molecular neuroscience, 14, 765181More Information

Go, Eun Jin; Ji, Jeongkyu; Kim, Yong Ho; Berta, Temugin; Park, Chul-Kyu  (2021). Transient Receptor Potential Channels and Botulinum Neurotoxins in Chronic Pain. Frontiers in molecular neuroscience, 14, 772719More Information

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temugin.berta@uc.edu