Caroline Billingsley , MD

Bachelor's Degree: College of Charleston Charleston, SC, 2002 (Biology, Philosophy)

Residency: Medical University of South Carolina Charleston, SC, 2012

Fellowship: The Ohio State University Wexner Medical Center Columbus, OH, 2015 (Gynecology Oncology)

American Board of Obstetrics and Gynecology (Gynecologic Oncology) (Certification Date: 04-13-2018 ) - (Recertification Date: to 12-31-2024 )

American Board of Obstetrics and Gynecology (Certification Date: 11-11-2016 ) - (Recertification Date: to 12-31-2024 )

Gynecologic Oncology

Adenomyosis

Adnexal Disease

Adnexal Tumors

Cervical Cancer

Dysgerminoma

Embryonal Carcinoma

Embryonal Tumors

Endometrial Cancer

Endometrial Stromal Sarcoma

Endometriosis

Fallopian Tube Cancer

Fibroids

Germ Cell and Embryona Cancers

Germ Cell Tumor

Gestational Trophoblastic Neoplasia

Human Papilloma Virus (HPV)

Krukenberg Tumor

Other Complicated Gynecologic Cancers

Ovarian Cancer

Ovarian Cyst

Pelvic Cancers

Pelvic Masses

Placenta Accreta

Precancer in the Vagina

Precancer in the Vulva

Precancers in the Cervix

Uterine Fibroids (Uterine leiomyoma)

Uterine Hemorrhage

Uterine Polyps (Endometrial Polyps)

Uterine Sarcoma

Vaginal Cancer

Vulvar Cancer

Gynecologic Oncology

Obstetrics and Gynecology

Gynecologic Oncology, Advanced Pelvic Surgery, Minimally Invasive Surgery - Robotic Surgery, Fertility Sparing Options, Oncofertility

2015 -To Present Assistant Professor, University of Cincinnati College of Medicine, Cincinnati, OH

2015 - Medical Director, Outpatient Clinic- Gynecologic Oncology, University of Cincinnati Cancer Institute, Cincinnati, OH

Grant: #MK3475-C93/GOG-3064 Investigators:Billingsley, Caroline 11-01-2021 -10-31-2024 Merck Sharp & Dohme Corp A Phase 3 study of pembrolizumab vs chemotherapy in dMMR advanced or recurrent endometrial carcinoma Role:PI 832712.50 Hold Level:Industry

Grant: #ACR-368-201 Investigators:Billingsley, Caroline 06-06-2023 -06-06-2026 GOG Foundation, Inc. A PHASE 1B/2 BASKET STUDY OF ACR-368 ASMONOTHERAPY IN COMBINATION WITHGEMCITABINE IN ADULT SUBJECTS WITHPLATINUM -RESISTANT OVARIAN CARCINOMA,ENDOMETRIAL ADENOCARCINOMA, ANDUROTHELIAL CARCINOMA Role:PI 132439.99 Hold Level:Non Profit

Grant: #ZN-c3-004 Investigators:Billingsley, Caroline 10-09-2023 -10-09-2026 K-Group Beta, Inc. A Phase 2 Open-Label, Multicenter Study to Evaluate Efficacy and Safety of ZN-c3 in Adult Women with Recurrent or Persistent Uterine Serous Carcinoma Role:PI 183258.75 Hold Level:Industry

Investigators:Billingsley, Caroline 05-05-2025 -05-05-2028 GOG Foundation, Inc. A Phase III Randomized Trial of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) with Cisplatin versus no HIPEC at the Time of Interval Cytoreductive Surgery followed by Niraparib Maintenance in Pati Role:PI 112856.55 Hold Level:Non Profit

Peer Reviewed Publications

Billingsley C.;Kenne K.;Cansino C.;Backes F.;Cohn D.;O'Malley D.;Copeland L.;Fowler J.;Salani R. (06-2015. ) The Use of Transvaginal Ultrasound in Type II Endometrial Cancer.International Journal of Gynecological Cancer, , 25 (5 ) ,858-862 More Information

Billingsley C.;Cohn D.;Mutch D.;Stephens J.;Suarez A.;Goodfellow P. (02-2015. ) Polymerase ε (POLE) mutations in endometrial cancer: clinical outcomes and implications for Lynch Syndrome testing.Cancer, , 121 (3 ) ,386-394 More Information

Billingsley C, Foote J, Korte J, Gagliardi E, M Kohler, Creasman WT. (12-2013. ) Evaluation of risk factors for infectious morbidity of postoperative gynecologic oncology patients: A Time for a New Paradigm?.Clinical Ovarian and other Gynecologic Cancer, , More Information

Salani R.;Billingsley C.;Crafton S. (01-01-2014. ) Cancer and pregnancy: An overview for obstetricians and gynecologists.American Journal of Obstetrics and Gynecology, , 211 (1 ) ,7-14 More Information

Backes F.;Billingsley C.;Martin D.;Tierney B.;Eisenhauer E.;Cohn D.;O'Malley D.;Salani R.;Copeland L.;Fowler J. (10-2014. ) Does intra-operative radiation at the time of pelvic exenteration improve survival for patients with recurrent, previously irradiated cervical, vaginal, or vulvar cancer? .Gynecologic Oncology, , 135 (1 ) ,95-99 More Information

Salani R.;Billingsley C.;Crafton S. (12-2013. ) Reply: Cancer and pregnancy: An overview for obstetricians and gynecologists.American Journal of Obstetrics and Gynecology, , 211 (1 ) ,83 More Information

Dempsey A.;Billingsley C.;Savage A.;Korte J. (06-01-2012. ) Predictors of long-acting reversible contraception use among unmarried young adults.American Journal of Obstetrics and Gynecology, , 206 (6 ) ,526.e1-526.e5 More Information

Billingsley C.;Kohler M.;Creasman W.;Madory J.;Young J. (04-01-2012. ) A case of parametrial lymph node involvement in stage IA2 squamous cell carcinoma of the cervix trea.Journal of Lower Genital Tract Disease, , 16 (2 ) ,145-148 More Information

Billingsley C.C.;Jacobson S.N.;Crafton S.M.;Crim A.K.;Li Q.;Hade E.M.;Cohn D.E.;Fowler J.M.;Copeland L.J.;Salani R.;Backes F.J.;O'Malley D.M. (09-2015. ) Evaluation of the Hematologic Safety of Same Day Versus Standard Administration (24- to 72-Hour Delay) of Pegfilgrastim in Gynecology Oncology Patients Undergoing Cytotoxic Chemotherapy.International Journal of Gynecological Cancer, , 25 (7 ) ,1331-1336 More Information

Huffman L.B.;Randolph L.K.;McCann G.A.;Billingsley C.;Hopkins M.;Cohn D.E.;Hundley A.F. (10-2013. ) Options for repair of rectus abdominis myocutaneous perineal/vaginal flap prolapse: A case series.Gynecologic Oncology Case Reports, , 7 ,1-3 More Information

Billingsley CC, O’Malley D, Hays J (02-2015. ) The role of anti-angiogenic therapy in the management of gynecologic malignancies: A review.Journal of OncoPathology, , 3 (1 ) ,77-87 More Information

Goodfellow PJ, Billingsley CC, Lankes HA, Ali S, Cohn DE, Broaddus RD, et al. (11-2015. ) Combined MSI, MLH1 methylation analysis and IHC for Lynch syndrome screening for 1002 endometrial cancers from GOG210: An NRG Oncology/Gynecologic Oncology Group study.Journal of Clinical Oncology, , 33 (36 ) ,4301 More Information

Hadad, Laura K; Billingsley, Caroline C (2017. ) Posterior reversible encephalopathy syndrome (PRES) associated with ovarian cancer and voltage-gated potassium channel antibodies: A case report.Gynecologic oncology reports, , 20 ,67-69 More Information

Baucom, Amanda; Herzog, Thomas; Jackson, Amanda; Wahab, Shaun A; Billingsley, Caroline (2021. ) A case of placenta previa with increta with a history of pelvic radiation.Gynecologic oncology reports, , 37 ,100800 More Information

Loreen, Amy; Polen-De, Clarissa; Monk, Bradley J; Jackson, Amanda L; Billingsley, Caroline C; Herzog, Thomas J (2021. ) The role of blinded independent radiologic review in ovarian cancer clinical trials: Discerning the value.Gynecologic oncology, , 161 (2 ) ,491-495 More Information

Wolf, Jennifer L; Billingsley, Caroline C; Kendler, Ady; Jackson, Amanda L (2020. ) Cervical Stratified Mucin-Producing Intraepithelial Lesion: A Systematic Review of Diagnosis and Management.Journal of lower genital tract disease, , 24 (3 ) ,259-264 More Information

Wolf, Jennifer; Jackson, Amanda; Herzog, Thomas; Kendler, Ady; Wahab, Shaun A; Billingsley, Caroline (2020. ) A case of a unique presentation of a primary vaginal endometrioid adenocarcinoma arising in the setting of a recurrent peritoneal inclusion cyst fistulized to the vagina.Gynecologic oncology reports, , 33 ,100585 More Information

Perry, Madeline F; Jackson, Amanda L; Herzog, Thomas J; Billingsley, Caroline C (2020. ) Early diagnosis and treatment challenges of endodermal sinus tumors: A case report.Case reports in women's health, , 27 ,e00198 More Information

Rothenberger, Rodger; Jackson, Amanda; Kendler, Ady; Herzog, Thomas; Billingsley, Caroline (2019. ) An unusual case of uterine PEComa presenting with disseminated intravascular coagulation.Gynecologic oncology reports, , 29 ,76-78 More Information

Billingsley, Caroline; Jackson, Amanda; Loreen, Amy (2019. ) 29-year-old with dyspareunia and vulvar mass: An unusual diagnosis of Bartholin's gland carcinoma.Gynecologic oncology reports, , 27 ,15-18 More Information

Bedard, Mary C; Chihanga, Tafadzwa; Carlile, Adrean; Jackson, Robert; Brusadelli, Marion G; Lee, Denis; VonHandorf, Andrew; Rochman, Mark; Dexheimer, Phillip J; Chalmers, Jeffrey; Nuovo, Gerard; Lehn, Maria; Williams, David E J; Kulkarni, Aditi; Carey, Molly; Jackson, Amanda; Billingsley, Caroline; Tang, Alice; Zender, Chad; Patil, Yash; Wise-Draper, Trisha M; Herzog, Thomas J; Ferris, Robert L; Kendler, Ady; Aronow, Bruce J; Kofron, Matthew; Rothenberg, Marc E; Weirauch, Matthew T; Van Doorslaer, Koenraad; Wikenheiser-Brokamp, Kathryn A; Lambert, Paul F; Adam, Mike; Steven Potter, S; Wells, Susanne I (2023. ) Single cell transcriptomic analysis of HPV16-infected epithelium identifies a keratinocyte subpopulation implicated in cancer.Nature communications, , 14 (1 ) ,1975 More Information

Backes, Floor J; Billingsley, Caroline C; Martin, Douglas D; Tierney, Brent J; Eisenhauer, Eric L; Cohn, David E; O'Malley, David M; Salani, Ritu; Copeland, Larry J; Fowler, Jeffrey M (2014. ) Does intra-operative radiation at the time of pelvic exenteration improve survival for patients with recurrent, previously irradiated cervical, vaginal, or vulvar cancer?.Gynecologic oncology, , 135 (1 ) ,95-9 More Information

Khadraoui, Hanaa; Herzog, Thomas J; Jackson, Amanda; Billingsley, Caroline (2023. ) Acute pulmonary complications in the setting of high risk gestational trophoblastic neoplasia and induction of chemotherapy.Gynecologic oncology reports, , 48 ,101224 More Information

Mirza, Mansoor R; Chase, Dana M; Slomovitz, Brian M; dePont Christensen, René; Novák, Zoltán; Black, Destin; Gilbert, Lucy; Sharma, Sudarshan; Valabrega, Giorgio; Landrum, Lisa M; Hanker, Lars C; Stuckey, Ashley; Boere, Ingrid; Gold, Michael A; Auranen, Annika; Pothuri, Bhavana; Cibula, David; McCourt, Carolyn; Raspagliesi, Francesco; Shahin, Mark S; Gill, Sarah E; Monk, Bradley J; Buscema, Joseph; Herzog, Thomas J; Copeland, Larry J; Tian, Min; He, Zangdong; Stevens, Shadi; Zografos, Eleftherios; Coleman, Robert L; Powell, Matthew A (2023. ) Dostarlimab for Primary Advanced or Recurrent Endometrial Cancer.The New England journal of medicine, , 388 (23 ) ,2145-2158 More Information

Editorial

Billingsley C, Copeland L (10-2014. ) OB.GYN. News, (Author)

Academic - University of Cincinnati Medical Center
231 Albert Sabin Way, MSB Room 4560
Cincinnati  Ohio, 45267-0526
Phone: 513-558-6926
Fax: 513-558-3558
caroline.billingsley@uc.edu