Caroline Billingsley , MD
Associate Professor of Clinical
University of Cincinnati Medical Center
231 Albert Sabin Way, MSB Room 4560
P.O. Box 670526
Cincinnati, Ohio 45267-0526
Phone 513-558-6926
Fax 513-558-3558
Email caroline.billingsley@uc.edu
Education
Bachelor's Degree: College of Charleston Charleston, SC, 2002 (Biology, Philosophy)
Residency: Medical University of South Carolina Charleston, SC, 2012
Fellowship: The Ohio State University Wexner Medical Center Columbus, OH, 2015 (Gynecology Oncology)
Certifications
American Board of Obstetrics and Gynecology (Gynecologic Oncology) (Certification Date: 04-13-2018 ) - (Recertification Date: to 12-31-2022 )
American Board of Obstetrics and Gynecology (Certification Date: 11-11-2016 ) - (Recertification Date: to 12-31-2022 )
Clinical Interests
Gynecologic Oncology
Adenomyosis
Adnexal Disease
Adnexal Tumors
Cervical Cancer
Dysgerminoma
Embryonal Carcinoma
Embryonal Tumors
Endometrial Cancer
Endometrial Stromal Sarcoma
Endometriosis
Fallopian Tube Cancer
Fibroids
Germ Cell and Embryona Cancers
Germ Cell Tumor
Gestational Trophoblastic Neoplasia
Human Papilloma Virus (HPV)
Krukenberg Tumor
Other Complicated Gynecologic Cancers
Ovarian Cancer
Ovarian Cyst
Pelvic Cancers
Pelvic Masses
Placenta Accreta
Precancer in the Vagina
Precancer in the Vulva
Precancers in the Cervix
Uterine Fibroids (Uterine leiomyoma)
Uterine Hemorrhage
Uterine Polyps (Endometrial Polyps)
Uterine Sarcoma
Vaginal Cancer
Vulvar Cancer
Specialities
Gynecologic Oncology
Obstetrics and Gynecology
Research and Practice Interests
Gynecologic Oncology, Advanced Pelvic Surgery, Minimally Invasive Surgery - Robotic Surgery, Fertility Sparing Options, Oncofertility
Positions and Work Experience
2015 -To Present Assistant Professor, University of Cincinnati College of Medicine, Cincinnati, OH
2015 - Medical Director, Outpatient Clinic- Gynecologic Oncology, University of Cincinnati Cancer Institute, Cincinnati, OH
Research Support
Grant: #MK3475-C93/GOG-3064 Investigators:Billingsley, Caroline 11-01-2021 -10-31-2024 Merck Sharp & Dohme Corp A Phase 3 study of pembrolizumab vs chemotherapy in dMMR advanced or recurrent endometrial carcinoma Role:PI 832712.50 Hold Level:Industry
Grant: #ACR-368-201 Investigators:Billingsley, Caroline 06-06-2023 -06-06-2026 GOG Foundation, Inc. A PHASE 1B/2 BASKET STUDY OF ACR-368 ASMONOTHERAPY IN COMBINATION WITHGEMCITABINE IN ADULT SUBJECTS WITHPLATINUM -RESISTANT OVARIAN CARCINOMA,ENDOMETRIAL ADENOCARCINOMA, ANDUROTHELIAL CARCINOMA Role:PI 132439.99 Hold Level:Non Profit
Grant: #ZN-c3-004 Investigators:Billingsley, Caroline 10-09-2023 -10-09-2026 K-Group Beta, Inc. A Phase 2 Open-Label, Multicenter Study to Evaluate Efficacy and Safety of ZN-c3 in Adult Women with Recurrent or Persistent Uterine Serous Carcinoma Role:PI 183258.75 Hold Level:Industry
Publications
Peer Reviewed Publications
Billingsley C.;Kenne K.;Cansino C.;Backes F.;Cohn D.;O'Malley D.;Copeland L.;Fowler J.;Salani R. (06-2015. ) The Use of Transvaginal Ultrasound in Type II Endometrial Cancer.International Journal of Gynecological Cancer, , 25 (5 ) ,858-862 More Information
Billingsley C.;Cohn D.;Mutch D.;Stephens J.;Suarez A.;Goodfellow P. (02-2015. ) Polymerase ε (POLE) mutations in endometrial cancer: clinical outcomes and implications for Lynch Syndrome testing.Cancer, , 121 (3 ) ,386-394 More Information
Billingsley C, Foote J, Korte J, Gagliardi E, M Kohler, Creasman WT. (12-2013. ) Evaluation of risk factors for infectious morbidity of postoperative gynecologic oncology patients: A Time for a New Paradigm?.Clinical Ovarian and other Gynecologic Cancer, , More Information
Salani R.;Billingsley C.;Crafton S. (01-01-2014. ) Cancer and pregnancy: An overview for obstetricians and gynecologists.American Journal of Obstetrics and Gynecology, , 211 (1 ) ,7-14 More Information
Backes F.;Billingsley C.;Martin D.;Tierney B.;Eisenhauer E.;Cohn D.;O'Malley D.;Salani R.;Copeland L.;Fowler J. (10-2014. ) Does intra-operative radiation at the time of pelvic exenteration improve survival for patients with recurrent, previously irradiated cervical, vaginal, or vulvar cancer? .Gynecologic Oncology, , 135 (1 ) ,95-99 More Information
Salani R.;Billingsley C.;Crafton S. (12-2013. ) Reply: Cancer and pregnancy: An overview for obstetricians and gynecologists.American Journal of Obstetrics and Gynecology, , 211 (1 ) ,83 More Information
Dempsey A.;Billingsley C.;Savage A.;Korte J. (06-01-2012. ) Predictors of long-acting reversible contraception use among unmarried young adults.American Journal of Obstetrics and Gynecology, , 206 (6 ) ,526.e1-526.e5 More Information
Billingsley C.;Kohler M.;Creasman W.;Madory J.;Young J. (04-01-2012. ) A case of parametrial lymph node involvement in stage IA2 squamous cell carcinoma of the cervix trea.Journal of Lower Genital Tract Disease, , 16 (2 ) ,145-148 More Information
Billingsley C.C.;Jacobson S.N.;Crafton S.M.;Crim A.K.;Li Q.;Hade E.M.;Cohn D.E.;Fowler J.M.;Copeland L.J.;Salani R.;Backes F.J.;O'Malley D.M. (09-2015. ) Evaluation of the Hematologic Safety of Same Day Versus Standard Administration (24- to 72-Hour Delay) of Pegfilgrastim in Gynecology Oncology Patients Undergoing Cytotoxic Chemotherapy.International Journal of Gynecological Cancer, , 25 (7 ) ,1331-1336 More Information
Huffman L.B.;Randolph L.K.;McCann G.A.;Billingsley C.;Hopkins M.;Cohn D.E.;Hundley A.F. (10-2013. ) Options for repair of rectus abdominis myocutaneous perineal/vaginal flap prolapse: A case series.Gynecologic Oncology Case Reports, , 7 ,1-3 More Information
Billingsley CC, O’Malley D, Hays J (02-2015. ) The role of anti-angiogenic therapy in the management of gynecologic malignancies: A review.Journal of OncoPathology, , 3 (1 ) ,77-87 More Information
Goodfellow PJ, Billingsley CC, Lankes HA, Ali S, Cohn DE, Broaddus RD, et al. (11-2015. ) Combined MSI, MLH1 methylation analysis and IHC for Lynch syndrome screening for 1002 endometrial cancers from GOG210: An NRG Oncology/Gynecologic Oncology Group study.Journal of Clinical Oncology, , 33 (36 ) ,4301 More Information
Hadad, Laura K; Billingsley, Caroline C (2017. ) Posterior reversible encephalopathy syndrome (PRES) associated with ovarian cancer and voltage-gated potassium channel antibodies: A case report.Gynecologic oncology reports, , 20 ,67-69 More Information
Baucom, Amanda; Herzog, Thomas; Jackson, Amanda; Wahab, Shaun A; Billingsley, Caroline (2021. ) A case of placenta previa with increta with a history of pelvic radiation.Gynecologic oncology reports, , 37 ,100800 More Information
Loreen, Amy; Polen-De, Clarissa; Monk, Bradley J; Jackson, Amanda L; Billingsley, Caroline C; Herzog, Thomas J (2021. ) The role of blinded independent radiologic review in ovarian cancer clinical trials: Discerning the value.Gynecologic oncology, , 161 (2 ) ,491-495 More Information
Wolf, Jennifer L; Billingsley, Caroline C; Kendler, Ady; Jackson, Amanda L (2020. ) Cervical Stratified Mucin-Producing Intraepithelial Lesion: A Systematic Review of Diagnosis and Management.Journal of lower genital tract disease, , 24 (3 ) ,259-264 More Information
Wolf, Jennifer; Jackson, Amanda; Herzog, Thomas; Kendler, Ady; Wahab, Shaun A; Billingsley, Caroline (2020. ) A case of a unique presentation of a primary vaginal endometrioid adenocarcinoma arising in the setting of a recurrent peritoneal inclusion cyst fistulized to the vagina.Gynecologic oncology reports, , 33 ,100585 More Information
Perry, Madeline F; Jackson, Amanda L; Herzog, Thomas J; Billingsley, Caroline C (2020. ) Early diagnosis and treatment challenges of endodermal sinus tumors: A case report.Case reports in women's health, , 27 ,e00198 More Information
Rothenberger, Rodger; Jackson, Amanda; Kendler, Ady; Herzog, Thomas; Billingsley, Caroline (2019. ) An unusual case of uterine PEComa presenting with disseminated intravascular coagulation.Gynecologic oncology reports, , 29 ,76-78 More Information
Billingsley, Caroline; Jackson, Amanda; Loreen, Amy (2019. ) 29-year-old with dyspareunia and vulvar mass: An unusual diagnosis of Bartholin's gland carcinoma.Gynecologic oncology reports, , 27 ,15-18 More Information
Bedard, Mary C; Chihanga, Tafadzwa; Carlile, Adrean; Jackson, Robert; Brusadelli, Marion G; Lee, Denis; VonHandorf, Andrew; Rochman, Mark; Dexheimer, Phillip J; Chalmers, Jeffrey; Nuovo, Gerard; Lehn, Maria; Williams, David E J; Kulkarni, Aditi; Carey, Molly; Jackson, Amanda; Billingsley, Caroline; Tang, Alice; Zender, Chad; Patil, Yash; Wise-Draper, Trisha M; Herzog, Thomas J; Ferris, Robert L; Kendler, Ady; Aronow, Bruce J; Kofron, Matthew; Rothenberg, Marc E; Weirauch, Matthew T; Van Doorslaer, Koenraad; Wikenheiser-Brokamp, Kathryn A; Lambert, Paul F; Adam, Mike; Steven Potter, S; Wells, Susanne I (2023. ) Single cell transcriptomic analysis of HPV16-infected epithelium identifies a keratinocyte subpopulation implicated in cancer.Nature communications, , 14 (1 ) ,1975 More Information
Backes, Floor J; Billingsley, Caroline C; Martin, Douglas D; Tierney, Brent J; Eisenhauer, Eric L; Cohn, David E; O'Malley, David M; Salani, Ritu; Copeland, Larry J; Fowler, Jeffrey M (2014. ) Does intra-operative radiation at the time of pelvic exenteration improve survival for patients with recurrent, previously irradiated cervical, vaginal, or vulvar cancer?.Gynecologic oncology, , 135 (1 ) ,95-9 More Information
Khadraoui, Hanaa; Herzog, Thomas J; Jackson, Amanda; Billingsley, Caroline (2023. ) Acute pulmonary complications in the setting of high risk gestational trophoblastic neoplasia and induction of chemotherapy.Gynecologic oncology reports, , 48 ,101224 More Information
Mirza, Mansoor R; Chase, Dana M; Slomovitz, Brian M; dePont Christensen, René; Novák, Zoltán; Black, Destin; Gilbert, Lucy; Sharma, Sudarshan; Valabrega, Giorgio; Landrum, Lisa M; Hanker, Lars C; Stuckey, Ashley; Boere, Ingrid; Gold, Michael A; Auranen, Annika; Pothuri, Bhavana; Cibula, David; McCourt, Carolyn; Raspagliesi, Francesco; Shahin, Mark S; Gill, Sarah E; Monk, Bradley J; Buscema, Joseph; Herzog, Thomas J; Copeland, Larry J; Tian, Min; He, Zangdong; Stevens, Shadi; Zografos, Eleftherios; Coleman, Robert L; Powell, Matthew A (2023. ) Dostarlimab for Primary Advanced or Recurrent Endometrial Cancer.The New England journal of medicine, , 388 (23 ) ,2145-2158 More Information
Additional Publications
Editorial
Billingsley C, Copeland L (10-2014. ) OB.GYN. News, (Author)
Contact Information
Academic - University of Cincinnati Medical Center
231 Albert Sabin Way, MSB Room 4560
Cincinnati
Ohio, 45267-0526
Phone: 513-558-6926
Fax: 513-558-3558
caroline.billingsley@uc.edu