Alexander Bondoc

Alexander J. Bondoc

Assistant Professor of Clinical Aff

Childrens Hospital Bldg R

COM Surgery Pediatric - 0054

Department of Pediatric Surgery
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio 45229

Professional Summary

Hepatobiliary, pediatrics, surgical oncology

Education

Bachelor's Degree, Georgetown University 2001 (English Literature)

Medical Degree, University of Michigan 2005

Research and Practice Interests

Biliary atresia, surgical oncology

Clinical Focus

General Surgery

Certifications

American Board of Surgery (Pediatric Surgery)

04/25/2017

American Board of Surgery

03/18/2013

Publications

Peer Reviewed Publications

Chang, Alex L; Cortez, Alexander R; Bondoc, Alexander; Schauer, Daniel P; Fitch, Angela; Shah, Shimul A; Woodle, Steve E; Diwan, Tayyab (2016. ) Metabolic syndrome in liver transplantation: A preoperative and postoperative concern.Surgery, , 160 (4 ) ,1111-7

Reznichenko, Aleksandr A; Bondoc, Alexander; Paterno, Flavio; Shah, Shimul A (2016. ) Hepatic Artery Pseudoaneurysm After Liver Transplantation.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, , 20 (7 ) ,1405-6

Mohanty, Sujit K; Donnelly, Bryan; Bondoc, Alexander; Jafri, Mubeen; Walther, Ashley; Coots, Abigail; McNeal, Monica; Witte, David; Tiao, Gregory M (2013. ) Rotavirus replication in the cholangiocyte mediates the temporal dependence of murine biliary atresia.PloS one, , 8 (7 ) ,e69069

Bondoc, Alexander J; Taylor, Janice A; Alonso, Maria H; Nathan, Jaimie D; Wang, Yu; Balistreri, William F; Bezerra, Jorge A; Ryckman, Frederick C; Tiao, Gregory M (2012. ) The beneficial impact of revision of Kasai portoenterostomy for biliary atresia: an institutional study.Annals of surgery, , 255 (3 ) ,570-6

Wang, Wei; Donnelly, Bryan; Bondoc, Alexander; Mohanty, Sujit K; McNeal, Monica; Ward, Richard; Sestak, Karol; Zheng, Shan; Tiao, Greg (2011. ) The rhesus rotavirus gene encoding VP4 is a major determinant in the pathogenesis of biliary atresia in newborn mice.Journal of virology, , 85 (17 ) ,9069-77

Bondoc, Alexander J; Jafri, Mubeen A; Donnelly, Bryan; Mohanty, Sujit K; McNeal, Monica M; Ward, Richard L; Tiao, Greg M (2009. ) Prevention of the murine model of biliary atresia after live rotavirus vaccination of dams.Journal of pediatric surgery, , 44 (8 ) ,1479-90

Jafri, Mubeen; Donnelly, Bryan; Bondoc, Alex; Allen, Steven; Tiao, Greg (2009. ) Cholangiocyte secretion of chemokines in experimental biliary atresia.Journal of pediatric surgery, , 44 (3 ) ,500-7

Jafri, Mubeen; Donnelly, Bryan; Allen, Steven; Bondoc, Alex; McNeal, Monica; Rennert, Paul D; Weinreb, Paul H; Ward, Richard; Tiao, Greg (2008. ) Cholangiocyte expression of alpha2beta1-integrin confers susceptibility to rotavirus-induced experimental biliary atresia.American journal of physiology. Gastrointestinal and liver physiology, , 295 (1 ) ,G16-G26

Lake C.M.;Tiao G.M.;Bondoc A.J. (12-01-2019. ) Surgical management of locally-advanced and metastatic hepatoblastoma.Seminars in Pediatric Surgery, , 28 (6 ) ,

Cortez A.R.;Kassam A.F.;Jenkins T.M.;Nathan C.J.;Nathan J.D.;Alonso M.H.;Ryckman F.C.;Tiao G.M.;Bondoc A.J. (11-01-2019. ) The role of surgical shunts in the treatment of pediatric portal hypertension.Surgery (United States), , 166 (5 ) ,907-913

Kocoshis S.;Goldschmidt M.;Nathan J.;El-Chammas K.;Bondoc A.;Tiao G.;Alonso M.;Ubesie A.;Cole C.;Kaul A. (07-01-2019. ) Esophageal dysmotility: An intrinsic feature of megacystis, microcolon, hypoperistalsis syndrome (MM.Journal of Pediatric Surgery, , 54 (7 ) ,1303-1307

Mohanty S.K.;Lobeck I.;Donnelly B.;Dupree P.;Walther A.;Mowery S.;Coots A.;Bondoc A.;Sheridan R.M.;Poling H.M.;Temple H.;McNeal M.;Sestak K.;Bansal R.;Tiao G. (01-01-2019. ) Rotavirus Reassortant–Induced Murine Model of Liver Fibrosis Parallels Human Biliary Atresia.Hepatology, ,

D'Souza A.;Shah R.;Gupta A.;Towbin A.;Alonso M.;Nathan J.;Bondoc A.;Tiao G.;Geller J. (11-01-2018. ) Surgical management of children and adolescents with upfront completely resected hepatocellular carc.Pediatric Blood and Cancer, , 65 (11 ) ,

Lobeck I.N.;Bondoc A.;Nolan H.;Frischer J.S.;Campbell K.M.;Ryan T.D.;Goldstein S.L.;Nathan J.D.;Alonso M.H.;Tiao G.M. (11-01-2018. ) Extracorporeal Membrane Oxygenation in a Patient with Biliary Atresia: Case and Review of Extracorpo.ASAIO journal (American Society for Artificial Internal Organs : 1992), , 64 (6 ) ,e191-e195

Bondoc A.;Abu-El-Haija M.;Nathan J. (08-01-2017. ) Pediatric pancreas transplantation, including total pancreatectomy with islet autotransplantation.Seminars in Pediatric Surgery, , 26 (4 ) ,250-256

Reznichenko A.;Bondoc A.;Paterno F.;Shah S. (07-01-2016. ) Hepatic Artery Pseudoaneurysm After Liver Transplantation.Journal of Gastrointestinal Surgery, , 20 (7 ) ,1405-1406

Knod J.;Bondoc A.;Garrison A.;Bischoff A.;Dickie B.;Frischer J. (11-01-2015. ) Concurrent esophageal atresia with tracheoesophageal fistula and Hirschsprung disease.Journal of Pediatric Surgery Case Reports, , 3 (11 ) ,499-500

Bondoc A.;Tiao G. (01-01-2010. ) Reply to Letter to the Editor by Petersen et al.Journal of Pediatric Surgery, , 45 (1 ) ,286-287

Book Chapter

Bondoc AJ. (2008 ) Sepsis and Surgical Infection The Mont Reid Surgical Handbook, 6th Edition .Philadelphia, Elsevier

Bondoc AJ. (2008 ) Carotid Disease The Mont Reid Surgical Handbook, 6th Edition .Philadelphia, Elsevier

Bondoc AJ. (2008 ) Peripheral Vascular Disease The Mont Reid Surgical Handbook, 6th Edition .Philadelphia, Elsevier

Bondoc A, Tiao G (2011 ) pancreatitis in the pediatric population Operative Pediatric Surgery, 2nd Edition .

Presentations

Poster Presentations

Bondoc A, Lyden T, Chepeha D (11-2002. ) Surgery with postoperative chemoradiation versus concomitant chemo-radiation for the tonsil-palate region: an assessment of speech, swallowing, and quality of life .Annual University of Michigan Medical School Summer Biomedical Research Forum, Ann Arbor, MI. .

Mammen JMV, Howington JA, Bondoc A, Reed MF (05-2006. ) Video-assisted thoracoscopic pneumonectomy for Swyer-James syndrome .Association of VA Surgeons Thirtieth Scientific Symposium, Cincinnati, OH. .

Bondoc A, Jafri M, Donnelly B, McNeal M, Tiao G. (02-2008. ) Prevention of rotavirus induced biliary atresia in a murine model using live rotavirus vaccine .Cincinnati Children’s Hospital Digestive Health Center Annual Retreat, Cincinnati, OH. .

Bondoc A, Donnelly B, Mohanty S, Jafri M, Jegga A, Xu H, Smith S, Tiao G (05-2009. ) Cholangiocyte-mediated initiation of inflammation in the murine model of biliary atresia .Ohio Chapter of the American College of Surgeons, Cleveland, OH. .

Bondoc A, Mohanty S, Donnelly B, Tiao G (05-2009. ) Temporal susceptibility of primary murine cholangiocytes mimics the murine model of biliary atresia .40th Annual American Pediatric Surgical Association Meeting, Fajardo, Puerto Rico. .

Mohanty SK, Donnelly B, Bondoc A, Tiao G (10-2010. ) Role of T-bet in the pathogenesis of biliary atresia .American Association for the Study of Liver Diseases 61st Annual Meeting, Boston, MA. .

Mohanty SK, Jafri M, Donnelly B, Bondoc A, McNeal MM, Witte D, Tiao G (11-2011. ) Distinct cholangiocyte response to injury determines the pathogenesis of the temporal component of murine biliary atresia .American Association for the Study of Liver Diseases 62nd Annual Meeting, San Francisco, CA. .

Paper Presentations

Bondoc A, Jafri M, Donnelly B, Tiao G (02-2008. ) Prevention of Rotavirus Induced Biliary Atresia in a Murine Model Using Live Rotavirus Vaccine .

Taylor J, Bondoc A, Tiao G, Alonso M, Ryckman F (05-2008. ) Revision of Kasai Portoenterostomy in a Select Population of Patients for Biliary Atresia: An Institutional Outcome Study .

Bondoc A, Jafri M, Donnelly B, McNeal M, Ward R, Tiao G (05-2008. ) Prevention of Rotavirus Induced Biliary Atresia in a Murine Model Using Live Rotavirus Vaccine .Cincinnati, OH.

Bondoc A, Jafri M, Donnelly B, Tiao G (06-2008. ) Prevention of Rotavirus Induced Biliary Atresia in a Murine Model Using Live Rotavirus Vaccine .Cincinnati, OH.

Bondoc A (11-2008. ) The Response of Biliary Epithelial Cells to Rotavirus Infection in the Murine Model of Biliary Atresia .Cincinnati, OH.

Bondoc A, Donnelly B, Mohanty S, Jafri M, Jegga A, Xu H, Smith S, Tiao G (05-2009. ) Cholangiocyte-mediated initiation of inflammation in the murine model of biliary atresia .Cincinnati, OH.

McNeal MM, Bondoc AJ, Jafri MA, Donnelly B, Mohanty SK, Ward RL, Tiao GM (06-2009. ) Prevention of Rotavirus Induced Biliary Atresia in a Murine Model Using Live Rotavirus Vaccine .Hamilton Island, Australia.

Bondoc A, Donnelly B, Mohanty S, Jafri M, Jegga A, Xu H, Smith S, Tiao G (10-2009. ) Cholangiocyte-mediated initiation of inflammation in the murine model of biliary atresia .Chicago, IL.

Donnelly B, Mohanty SK, Wang W, Bondoc A, McNeal MM, Ward RL, Meller J, Sestak K, Tiao G (10-2010. ) Rhesus rotavirus gene segment 4 induces the murine model of biliary atresia .Boston, MA.

Honors and Awards

NIH T32 Grant, Summer Biomedical Research Program, University of Michigan Medical School, 2002

Alpha Sigma Nu Honor Society, Georgetown University, May 2001

Phi Beta Kappa Honor Society, Georgetown University, May 2001

Finalist, Cincinnati Surgical Society Resident Research Competition, 2008

Finalist, University of Cincinnati Resident Research Competition, 2008

First Place Abstract, University of Cincinnati Resident Research Competition, 2009

Alpha Omega Alpha Honor Society, University of Cincinnati, 2011

Post Graduate Training and Education

07-2005-To Present Resident in General Surgery, University of Cincinnati College of Medicine,

07-2007-06-2009 Pediatric Surgery Research Fellow, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH,

Professional Affiliation

American College of Surgeons (ACS), Resident Member, 2005 to present

1998 -2001: EMT-Basic, Georgetown Emergency Response Medical Service, Washington, DC

1998: Patient Assistant and Transport Volunteer, Good Samaritan Hospital, Cincinnati, OH

2000 -2001: Georgetown Writing Center Tutor and English Literature Teaching Assistant, Georgetown University

2000: Research Intern, The National Assembly on School-Based Health Care, Washington, DC

2002 -2005: Research Assistant, Department of Otolaryngology (Dr. Douglas Chepeha), University of Michigan Medical School

07-2005 -To Present: Clinical Instructor, University of Cincinnati College of Medicine, Cincinnati, OH

Ad Hoc Reviewer, Archives of Surgery, 2009-present

Contact Information

Academic - Department of Pediatric Surgery
Cincinnati Children's Hospital Medical Center
Cincinnati  Ohio, 45229
Phone: 513-636-4371
alex.bondoc@cchmc.org