Pierce Boyne

Pierce Boyne

Associate Professor

Co-Director, UC Neurorecovery Laboratory and PhD Program in Health and Rehabilitation Sciences

Health Sciences Building - Rm 267
3225 Eden Avenue
PO Box 670394
Cincinnati, Ohio 45267
Phone 513-558-7499
Fax 513-558-7474
Email pierce.boyne@uc.edu

Professional Summary

Dr. Pierce Boyne, PT, DPT, PhD, NCS is an Associate Professor in the Department of Rehabilitation, Exercise Science and Nutrition Sciences. He earned his Doctorate in Physical Therapy at the University of Cincinnati in 2010, Neurologic Clinical Specialist certification from the American Board of Physical Therapy Specialties in 2013 and his PhD in Epidemiology in 2017, examining aerobic exercise testing and training for people who have had a stroke. His current research aims to understand how the brain contributes to walking capacity, how that control is affected by brain injuries like stroke and how to best intervene to facilitate walking recovery. This work has been supported by the National Institutes of Health, American Heart Association, Foundation for Physical Therapy Research, and other organizations. Dr. Boyne also co-directs the interdisciplinary UC Neurorecovery Laboratory and the PhD Program in Health and Rehabilitation Sciences at UC.

Education

PhD in Epidemiology : University of Cincinnati 2017

Doctorate in Physical Therapy: University of Cincinnati 2010

BS in Health Sciences: University of Cincinnati 2007

Research and Practice Interests

stroke recovery and rehabilitation, neural control of walking, neuroplasticity, aerobic exercise

Research Support

Grant: #R01HD093694 Investigators:Awosika, Oluwole; Boyne, Pierce; Carl, Daniel; Dunning, Kari; Gerson, Myron; Kissela, Brett 04-03-2018 -02-28-2023 National Institute of Child Health and Human Development High-Intensity Interval Training to Recover Walking Post-Stroke: HIT-Stroke Trial Role:PI $717,717.00 Awarded Level:Federal

Grant: #17MCPRP33670446 Investigators:Boyne, Pierce; Dunning, Kari; Kissela, Brett 07-01-2017 -06-30-2019 American Heart Association - National Chapter Priming the Brain for Stroke Recovery: Optimizing the Neurotrophic Effects of Aerobic Exercise Role:PI $76,786.00 Active Level:Private Non-Profit

Grant: #EFIT Nexstim Investigators:Boyne, Pierce; Dunning, Kari; Kissela, Brett 02-01-2017 -01-31-2018 Nexstim, Inc. Efit Trial - Nexstim NBT System Role:Collaborator $356,523.75 Active Level:Industry

Grant: #AY2014-15 Investigators:Boyne, Pierce 05-01-2015 -04-30-2016 UC's University Research Council Optimizing Exercise Testing After Stroke Role:PI $12,000.00 Active Level:Internal UC

Grant: #R01HD093694 Investigators:Awosika, Oluwole; Boyne, Pierce; Carl, Daniel 07-01-2023 -06-30-2028 National Institute of Child Health and Human Development High-Intensity Interval Training to Recover Walking Post-Stroke: HIT-Stroke Trial 2 Role:PI 708953.00 Awarded Level:Federal

Publications

Peer Reviewed Publications

Carl, Daniel; Whitesel, Dustyn; Meyrose, Colleen; Westover, Jennifer; Khoury, Jane; Gerson, Myron; Kissela, Brett; Dunning, Kari; Boyne, Pierce (2022. ) A 3-Min Recumbent Stepper Test in Chronic Stroke.PM & R : the journal of injury, function, and rehabilitation, , More Information

Moore, Sarah A; Boyne, Pierce; Fulk, George; Verheyden, Geert; Fini, Natalie A (2022. ) Walk the Talk: Current Evidence for Walking Recovery After Stroke, Future Pathways and a Mission for Research and Clinical Practice.Stroke, , 53 (11 ) ,3494-3505 More Information

Boyne, Pierce; DiFrancesco, Mark; Awosika, Oluwole O; Williamson, Brady; Vannest, Jennifer (2022. ) Mapping the human corticoreticular pathway with multimodal delineation of the gigantocellular reticular nucleus and high-resolution diffusion tractography.Journal of the neurological sciences, , 434 ,120091 More Information

Awosika, Oluwole O; Chan, Dorothy; Rizik, Bridget A; Sucharew, Heidi J; Boyne, Pierce; Bhattacharya, Amit; Dunning, Kari; Kissela, Brett M (2022. ) Serial Backward Locomotor Treadmill Training Improves Bidirectional Walking Performance in Chronic Stroke.Frontiers in neurology, , 13 ,800757 More Information

Boyne, Pierce; Doren, Sarah; Scholl, Victoria; Staggs, Emily; Whitesel, Dustyn; Carl, Daniel; Shatz, Rhonna; Sawyer, Russell; Awosika, Oluwole O; Reisman, Darcy S; Billinger, Sandra A; Kissela, Brett; Vannest, Jennifer; Dunning, Kari (2022. ) Preliminary Outcomes of Combined Treadmill and Overground High-Intensity Interval Training in Ambulatory Chronic Stroke.Frontiers in neurology, , 13 ,812875 More Information

Awosika, Oluwole O; Chan, Dorothy; Sucharew, Heidi J; Boyne, Pierce; Bhattacharya, Amit; Dunning, Kari; Kissela, Brett M (2022. ) Backward Locomotor Treadmill Training Differentially Improves Walking Performance across Stroke Walking Impairment Levels.Brain sciences, , 12 (2 ) , More Information

Boyne, Pierce; Awosika, Oluwole O; Luo, Yu (2021. ) Mapping the corticoreticular pathway from cortex-wide anterograde axonal tracing in the mouse.Journal of neuroscience research, , 99 (12 ) ,3392-3405 More Information

Miller, Allison; Reisman, Darcy S; Billinger, Sandra A; Dunning, Kari; Doren, Sarah; Ward, Jaimie; Wright, Henry; Wagner, Erin; Carl, Daniel; Gerson, Myron; Awosika, Oluwole; Khoury, Jane; Kissela, Brett; Boyne, Pierce (2021. ) Moderate-intensity exercise versus high-intensity interval training to recover walking post-stroke: protocol for a randomized controlled trial.Trials, , 22 (1 ) ,457 More Information

Boyne, Pierce; Doren, Sarah; Scholl, Victoria; Staggs, Emily; Whitesel, Dustyn; Maloney, Thomas; Awosika, Oluwole; Kissela, Brett; Dunning, Kari; Vannest, Jennifer (2021. ) Functional magnetic resonance brain imaging of imagined walking to study locomotor function after stroke.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, , 132 (1 ) ,167-177 More Information

Fulk, George D; Boyne, Pierce; Hauger, Makenzie; Ghosh, Raktim; Romano, Samantha; Thomas, Jonathan; Slutzky, Amy; Klingman, Karen (2020. ) The Impact of Sleep Disorders on Functional Recovery and Participation Following Stroke: A Systematic Review and Meta-Analysis.Neurorehabilitation and neural repair, , 34 (11 ) ,1050-1061 More Information

Awosika, Oluwole O; Matthews, Saira; Staggs, Emily J; Boyne, Pierce; Song, Xiao; Rizik, Bridget A; Sucharew, Heidi J; Zhang, Christina; Mungcal, Gabrielle; Moudgal, Rohitha; Bhattacharya, Amit; Dunning, Kari; Woo, Daniel; Kissela, Brett M (2020. ) Backward locomotor treadmill training combined with transcutaneous spinal direct current stimulation in stroke: a randomized pilot feasibility and safety study.Brain communications, , 2 (1 ) ,fcaa045 More Information

Boyne, Pierce; Meyrose, Colleen; Westover, Jennifer; Whitesel, Dustyn; Hatter, Kristal; Reisman, Darcy S; Carl, Daniel; Khoury, Jane C; Gerson, Myron; Kissela, Brett; Dunning, Kari (2020. ) Effects of Exercise Intensity on Acute Circulating Molecular Responses Poststroke.Neurorehabilitation and neural repair, , 34 (3 ) ,222-234 More Information

Boyne, Pierce; Scholl, Victoria; Doren, Sarah; Carl, Daniel; Billinger, Sandra A; Reisman, Darcy S; Gerson, Myron; Kissela, Brett; Vannest, Jennifer; Dunning, Kari (2020. ) Locomotor training intensity after stroke: Effects of interval type and mode.Topics in stroke rehabilitation, , 1-11 More Information

Roediger, Jan; Artusi, Carlo Alberto; Romagnolo, Alberto; Boyne, Pierce; Zibetti, Maurizio; Lopiano, Leonardo; Espay, Alberto J; Fasano, Alfonso; Merola, Aristide (2019. ) Effect of subthalamic deep brain stimulation on posture in Parkinson's disease: A blind computerized analysis.Parkinsonism & related disorders, , 62 ,122-127 More Information

Boyne, Pierce; Meyrose, Colleen; Westover, Jennifer; Whitesel, Dustyn; Hatter, Kristal; Reisman, Darcy S; Cunningham, David; Carl, Daniel; Jansen, Connor; Khoury, Jane C; Gerson, Myron; Kissela, Brett; Dunning, Kari (2019. ) Exercise intensity affects acute neurotrophic and neurophysiological responses poststroke.Journal of applied physiology (Bethesda, Md. : 1985), , 126 (2 ) ,431-443 More Information

Boyne, Pierce; Maloney, Thomas; DiFrancesco, Mark; Fox, Michael D; Awosika, Oluwole; Aggarwal, Pushkar; Woeste, Jennifer; Jaroch, Laurel; Braswell, Daniel; Vannest, Jennifer (2018. ) Resting-state functional connectivity of subcortical locomotor centers explains variance in walking capacity.Human brain mapping, , 39 (12 ) ,4831-4843 More Information

Boyne, Pierce; Billinger, Sandra; MacKay-Lyons, Marilyn; Barney, Brian; Khoury, Jane; Dunning, Kari (2017. ) Aerobic Exercise Prescription in Stroke Rehabilitation: A Web-Based Survey of US Physical Therapists.Journal of neurologic physical therapy : JNPT, , 41 (2 ) ,119-128 More Information

Carl, Daniel L; Boyne, Pierce; Rockwell, Bradley; Gerson, Myron; Khoury, Jane; Kissela, Brett; Dunning, Kari (2017. ) Preliminary safety analysis of high-intensity interval training (HIIT) in persons with chronic stroke.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, , 42 (3 ) ,311-318 More Information

Boyne, Pierce; Welge, Jeffrey; Kissela, Brett; Dunning, Kari (2017. ) Factors Influencing the Efficacy of Aerobic Exercise for Improving Fitness and Walking Capacity After Stroke: A Meta-Analysis With Meta-Regression.Archives of physical medicine and rehabilitation, , 98 (3 ) ,581-595 More Information

Boyne, Pierce; Reisman, Darcy; Brian, Michael; Barney, Brian; Franke, Ava; Carl, Daniel; Khoury, Jane; Dunning, Kari (2017. ) Ventilatory threshold may be a more specific measure of aerobic capacity than peak oxygen consumption rate in persons with stroke.Topics in stroke rehabilitation, , 24 (2 ) ,149-157 More Information

Fulk, George D; He, Ying; Boyne, Pierce; Dunning, Kari (2017. ) Predicting Home and Community Walking Activity Poststroke.Stroke, , 48 (2 ) ,406-411 More Information

Boyne, Pierce; Dunning, Kari; Carl, Daniel; Gerson, Myron; Khoury, Jane; Rockwell, Bradley; Keeton, Gabriela; Westover, Jennifer; Williams, Alesha; McCarthy, Michael; Kissela, Brett (2016. ) High-Intensity Interval Training and Moderate-Intensity Continuous Training in Ambulatory Chronic Stroke: Feasibility Study.Physical therapy, , 96 (10 ) ,1533-1544 More Information

Boyne, Pierce; Buhr, Sarah; Rockwell, Bradley; Khoury, Jane; Carl, Daniel; Gerson, Myron; Kissela, Brett; Dunning, Kari (2015. ) Predicting Heart Rate at the Ventilatory Threshold for Aerobic Exercise Prescription in Persons With Chronic Stroke.Journal of neurologic physical therapy : JNPT, , 39 (4 ) ,233-40 More Information

Boyne, Pierce; Dunning, Kari; Carl, Daniel; Gerson, Myron; Khoury, Jane; Kissela, Brett (2015. ) Within-session responses to high-intensity interval training in chronic stroke.Medicine and science in sports and exercise, , 47 (3 ) ,476-84 More Information

Billinger, Sandra A; Boyne, Pierce; Coughenour, Eileen; Dunning, Kari; Mattlage, Anna (2015. ) Does aerobic exercise and the FITT principle fit into stroke recovery?.Current neurology and neuroscience reports, , 15 (2 ) ,519 More Information

Page, Stephen J; Fulk, George D; Boyne, Pierce (2012. ) Clinically important differences for the upper-extremity Fugl-Meyer Scale in people with minimal to moderate impairment due to chronic stroke.Physical therapy, , 92 (6 ) ,791-8 More Information

Boyne, Pierce; Israel, Susan; Dunning, Kari (2011. ) Speed-dependent body weight supported sit-to-stand training in chronic stroke: a case series.Journal of neurologic physical therapy : JNPT, , 35 (4 ) ,178-84 More Information

Badke, Mary Beth; Sherman, Jack; Boyne, Pierce; Page, Stephen; Dunning, Kari (2011. ) Tongue-based biofeedback for balance in stroke: results of an 8-week pilot study.Archives of physical medicine and rehabilitation, , 92 (9 ) ,1364-70 More Information

Fulk, George D; Ludwig, Miriam; Dunning, Kari; Golden, Sue; Boyne, Pierce; West, Trent (2011. ) Estimating clinically important change in gait speed in people with stroke undergoing outpatient rehabilitation.Journal of neurologic physical therapy : JNPT, , 35 (2 ) ,82-9 More Information

Boyne, Pierce; Dunning, Kari; Levine, Peter; Hermann, Valerie Hill; Page, Stephen J (2010. ) Orthotic functional electrical stimulation following botulinum toxin for a young adult with severe hand impairment due to childhood stroke.Physiotherapy theory and practice, , 26 (4 ) ,267-74 More Information

Fulk, George D; Ludwig, Miriam; Dunning, Kari; Golden, Sue; Boyne, Pierce; West, Trent How much change in the stroke impact scale-16 is important to people who have experienced a stroke?.Topics in stroke rehabilitation, , 17 (6 ) ,477-83 More Information

Boyne, Pierce; Dunning, Kari; Carl, Daniel; Gerson, Myron; Khoury, Jane; Kissela, Brett High-intensity interval training in stroke rehabilitation.Topics in stroke rehabilitation, , 20 (4 ) ,317-30 More Information

Palmer, Jacqueline A; Whitaker, Alicen A; Payne, Aiden M; Bartsch, Bria L; Reisman, Darcy S; Boyne, Pierce E; Billinger, Sandra A (2023. ) Aerobic Exercise Improves Cortical Inhibitory Function After Stroke: A Preliminary Investigation.Journal of neurologic physical therapy : JNPT, , More Information

Lin, David J; Hardstone, Richard; DiCarlo, Julie A; Mckiernan, Sydney; Snider, Samuel B; Jacobs, Hannah; Erler, Kimberly S; Rishe, Kelly; Boyne, Pierce; Goldsmith, Jeff; Ranford, Jessica; Finklestein, Seth P; Schwamm, Lee H; Hochberg, Leigh R; Cramer, Steven C (2023. ) Distinguishing Distinct Neural Systems for Proximal vs Distal Upper Extremity Motor Control After Acute Stroke.Neurology, , More Information

Boyne, Pierce; Billinger, Sandra A; Reisman, Darcy S; Awosika, Oluwole O; Buckley, Sofia; Burson, Jamiah; Carl, Daniel; DeLange, Matthew; Doren, Sarah; Earnest, Melinda; Gerson, Myron; Henry, Madison; Horning, Alli; Khoury, Jane C; Kissela, Brett M; Laughlin, Abigail; McCartney, Kiersten; McQuaid, Thomas; Miller, Allison; Moores, Alexandra; Palmer, Jacqueline A; Sucharew, Heidi; Thompson, Elizabeth D; Wagner, Erin; Ward, Jaimie; Wasik, Emily Patton; Whitaker, Alicen A; Wright, Henry; Dunning, Kari (2023. ) Optimal Intensity and Duration of Walking Rehabilitation in Patients With Chronic Stroke: A Randomized Clinical Trial.JAMA neurology, , 80 (4 ) ,342-351 More Information

Boyne, Pierce; Miller, Allison; Schwab, Sarah M; Sucharew, Heidi; Carl, Daniel; Billinger, Sandra A; Reisman, Darcy S (2023. ) Training parameters and longitudinal adaptations that most strongly mediate walking capacity gains from high-intensity interval training post-stroke.medRxiv : the preprint server for health sciences, , More Information

Honors and Awards

2020 Faculty Excellence Award University of Cincinnati Offices of Research & the Provost

2017 -2023 Loan Repayment Program Award National Institutes of Health

2017 Excellence in Research Award UC College of Allied Health Sciences

2016 -2018 KL2 Training Grant “Mechanisms of Walking Recovery After Stroke” Subaward to KL2TR001426 “Cincinnati Center for Clinical and Translational Sciences and Training” National Institutes of Health

2015 PT Rock Star Ohio Physical Therapy Association Annual Conference

2014 Scot C. Irwin Award for outstanding cardiovascular/pulmonary studies American Physical Therapy Association, Cardiovascular/Pulmonary Section

2014 Promotion of Doctoral Studies (PODS I) Scholarship Foundation for Physical Therapy

2012 Recent Graduate Achievement Award UC College of Allied Health Sciences

2009 Scholarship of Excellence Association of Schools of Allied Health Professions

2008 Physical Therapy Student of the Year Nomination Ohio Physical Therapy Association

2007 ”Doing the RITE Thing” Award Christ Hospital, Cincinnati, OH

Contact Information

Academic - Health Sciences Building - Rm 267
3225 Eden Avenue
Cincinnati  Ohio, 45267
Phone: 513-558-7499
Fax: 513-558-7474
pierce.boyne@uc.edu