Debra Lynn Breneman, MD

Bachelor's Degree: Iowa State University Ames, IA, 1977 (Dual Majors Zoology and Psychology; Minor in Chemistry)

Doctor of Medicine: University of Iowa Iowa City, IA, 1981

Dermatology Residency: University of Cincinnati Medical Center Cincinnati, OH, 1985

American Board of Dermatology (Certification Date: 11-04-1985 )

My research interests are in 2 areas:dermato pharmacology;urtaneous lymphomas.Dermatopharmacology:conducting clinical research trials to evaluate the efficacy and safety of various drugs in the treatment of dermatologic diseases.Cutaneous lymphomas:evaluation and treatment of patients with cutaneous lymphomas including B-cell lymphomas including B-cell lymphomas, mycoses fungaide and other cutaneous T-cell lymphoma, and miscellaneous types of cutaneous lymphomas as well as conducting clinical research in this area.

Grant: #HS0005 Investigators:Breneman, Debra 12-01-2021 -11-30-2024 Parexel International, LLC A Phase 3, Open-label, parallel group, multicenter, extension study evaluating the long-term treatment of bimekizumab in study participants with moderate to severe hidradenitis suppurativa Role:PI 522345.00 Hold Level:Industry

Grant: #LP0190-1488 Investigators:Breneman, Debra 09-01-2021 -08-31-2024 LEO Pharma A phase 2 trial to evaluate the efficacy and safety of orally-administered LEO 152020 compared with placebo during a 16-week treatment period in adults with moderate to severe atopic dermatitis Role:PI 220313.16 Hold Level:Industry

Grant: #CBI_2022_MF_DevVal_001 Investigators:Breneman, Debra 05-29-2023 -05-28-2026 Castle Biosciences, Inc. Development and Validation of an Ancillary Diagnostic Test for Mycosis Fungoides (SIGNAL-MF) Role:PI 0.00 Hold Level:Industry

Grant: #230LE301 Investigators:Breneman, Debra 05-29-2023 -05-28-2026 IQVIA Clinical Trial Payments A Phase 2/3 Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of BIIB059 in Participants with Active Cutaneous Lupus Erythematosus with or without Sys Role:PI 0.00 Hold Level:Industry

Grant: #INCB 54707-301 Investigators:Breneman, Debra 06-14-2023 -03-12-2026 Incyte Corporation A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Efficacy and Safety Study of Povorcitinib (INCB054707) in Participants With Moderate to Severe Hidradenitis Suppurativa(STOP-HS1) Role:PI 325877.00 Hold Level:Industry

Peer Reviewed Publications

Edinger, James T; Lorenzo, Cynthia R; Breneman, Debra L; Swerdlow, Steven H  (2011). Primary cutaneous marginal zone lymphoma with subclinical cutaneous involvement and biclonality. Journal of cutaneous pathology, 38 (9) , 724-30More Information

Breneman, Debra L; Storer, Timothy J; Breneman, John C; Mutasim, Diya F  (2008). Methotrexate-induced cutaneous ulceration in patients with erythrodermic mycosis fungoides. Therapeutics and clinical risk management, 4 (5) , 1135-41More Information

Breneman, Debra L; Raju, Uma S; Breneman, John C; Steele, Paul E; McFadden, David W; Cualing, Hernani D; Nussbaum, Michael S; Swerdlow, Steven H  (2003). Lymph node grading for staging of mycosis fungoides may benefit from examination of multiple excised lymph nodes. Journal of the American Academy of Dermatology, 48 (5) , 702-6More Information

Kulow, Brittain F; Cualing, Hernani; Steele, Paul; VanHorn, Judi; Breneman, John C; Mutasim, Diya F; Breneman, Debra LProgression of cutaneous B-cell pseudolymphoma to cutaneous B-cell lymphoma. Journal of cutaneous medicine and surgery, 6 (6) , 519-28More Information

Breneman, D L; Hanifin, J M; Berge, C A; Keswick, B H; Neumann, P B  (2000). The effect of antibacterial soap with 1.5% triclocarban on Staphylococcus aureus in patients with atopic dermatitis. Cutis, 66 (4) , 296-300

Adamick, C M; Breneman, D L  (2000). Diffuse and progressive papules and nodules. Archives of dermatology, 136 (6) , 793, 796

Adamick, ; Breneman,  (2000). Off-Center Fold: Diffuse and Progressive Papules and Nodules. Archives of dermatology, 136 (6) , 791-796

Berberian, B J; Breneman, D L; Drake, L A; Gratton, D; Raimir, S S; Phillips, S; Sulica, V I; Bernstein, J E  (1999). The addition of topical doxepin to corticosteroid therapy: an improved treatment regimen for atopic dermatitis. International journal of dermatology, 38 (2) , 145-8More Information

Lebwohl, M G; Breneman, D L; Goffe, B S; Grossman, J R; Ling, M R; Milbauer, J; Pincus, S H; Sibbald, R G; Swinyer, L J; Weinstein, G D; Lew-Kaya, D A; Lue, J C; Gibson, J R; Sefton, J  (1998). Tazarotene 0.1% gel plus corticosteroid cream in the treatment of plaque psoriasis. Journal of the American Academy of Dermatology, 39 (4 Pt 1) , 590-6More Information

Ploysangam, T; Breneman, D L; Mutasim, D F  (1998). Cutaneous pseudolymphomas. Journal of the American Academy of Dermatology, 38 (6 Pt 1) , 877-95; quiz 896-7More Information

Koo, J; Cuffie, C A; Tanner, D J; Bressinck, R; Cornell, R C; DeVillez, R L; Edwards, L; Breneman, D L; Piacquadio, D J; Guzzo, C A; Monroe, E WMometasone furoate 0.1%-salicylic acid 5% ointment versus mometasone furoate 0.1% ointment in the treatment of moderate-to-severe psoriasis: a multicenter study. Clinical therapeutics, 20 (2) , 283-91

Breneman, D L; Stewart, D; Hevia, O; Hino, P D; Drake, L A  (1998). A double-blind, multicenter clinical trial comparing efficacy of once-daily metronidazole 1 percent cream to vehicle in patients with rosacea. Cutis, 61 (1) , 44-7

Breneman, D L  (1996). Cetirizine versus hydroxyzine and placebo in chronic idiopathic urticaria. The Annals of pharmacotherapy, 30 (10) , 1075-9More Information

Breneman, D L  (1996). Evaluation of cutaneous lymphomas. Comprehensive therapy, 22 (3) , 169-74

Fivenson, D P; Breneman, D L; Rosen, G B; Hersh, C S; Cardone, S; Mutasim, D  (1994). Nicotinamide and tetracycline therapy of bullous pemphigoid. Archives of dermatology, 130 (6) , 753-8

Goldschmidt, H; Breneman, J C; Breneman, D L  (1994). Ionizing radiation therapy in dermatology. Journal of the American Academy of Dermatology, 30 (2 Pt 1) , 157-82; quiz 183-6More Information

Breneman, D L; Breneman, J C  (1993). Cutaneous T-cell lymphoma mimicking porokeratosis of Mibelli. Journal of the American Academy of Dermatology, 29 (6) , 1046-8More Information

Doebbeling, B N; Breneman, D L; Neu, H C; Aly, R; Yangco, B G; Holley, H P; Marsh, R J; Pfaller, M A; McGowan, J E; Scully, B E  (1993). Elimination of Staphylococcus aureus nasal carriage in health care workers: analysis of six clinical trials with calcium mupirocin ointment. The Mupirocin Collaborative Study Group. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 17 (3) , 466-74More Information

Breneman, D L; Ariano, M C  (1993). Successful treatment of acne vulgaris in women with a new topical sodium sulfacetamide/sulfur lotion. International journal of dermatology, 32 (5) , 365-7More Information

Foss, F M; Ihde, D C; Breneman, D L; Phelps, R M; Fischmann, A B; Schechter, G P; Linnoila, I; Breneman, J C; Cotelingam, J D; Ghosh, B C  (1992). Phase II study of pentostatin and intermittent high-dose recombinant interferon alfa-2a in advanced mycosis fungoides/Sézary syndrome. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 10 (12) , 1907-13More Information

Breneman, D L; Cardone, J S; Blumsack, R F; Lather, R M; Searle, E A; Pollack, V E  (1992). Topical capsaicin for treatment of hemodialysis-related pruritus. Journal of the American Academy of Dermatology, 26 (1) , 91-4More Information

Smith, E B; Breneman, D L; Griffith, R F; Hebert, A A; Hickman, J G; Maloney, J M; Millikan, L E; Sulica, V I; Dromgoole, S H; Sefton, J  (1992). Double-blind comparison of naftifine cream and clotrimazole/betamethasone dipropionate cream in the treatment of tinea pedis. Journal of the American Academy of Dermatology, 26 (1) , 125-7More Information

Breneman, D L; Nartker, A L; Ballman, E A; Pruemer, J M; Blumsack, R F; Davis, M; Breneman, J C  (1991). Topical mechlorethamine in the treatment of mycosis fungoides. Uniformity of application and potential for environmental contamination. Journal of the American Academy of Dermatology, 25 (6 Pt 1) , 1059-64More Information

Kleier, R S; Breneman, D L; Boiko, S  (1991). Generalized pustulation as a manifestation of the anticonvulsant hypersensitivity syndrome. Archives of dermatology, 127 (9) , 1361-4

Supapannachart, N; Breneman, D L; Linnemann, C C  (1991). Isolation of human immunodeficiency virus type 1 in cutaneous blister fluid. Archives of dermatology, 127 (8) , 1198-200

Robinson, M K; Parsell, K W; Breneman, D L; Cruze, C A  (1991). Evaluation of the primary skin irritation and allergic contact sensitization potential of transdermal triprolidine. Fundamental and applied toxicology : official journal of the Society of Toxicology, 17 (1) , 103-19

Fivenson, D P; Breneman, D L; Wander, A H  (1990). Kaposi's varicelliform eruption. Absence of ocular involvement. Archives of dermatology, 126 (8) , 1037-9

Breneman, D L  (1990). Use of mupirocin ointment in the treatment of secondarily infected dermatoses. Journal of the American Academy of Dermatology, 22 (5 Pt 1) , 886-92More Information

Fivenson, D P; Breneman, D L  (1989). A rapidly progressive papulovesicular eruption. Eczema herpeticum/Kaposi's varicelliform eruption. Archives of dermatology, 125 (11) , 1570, 1572-3More Information

Fivenson, D P; Crump, G; Scheele, P; Breneman, D L  (1989). Systemic lupus erythematosus developing in a patient with longstanding pulmonary sarcoidosis. The Journal of rheumatology, 16 (8) , 1116-9

Belz, J; Breneman, D L; Nordlund, J J; Solinger, A  (1989). Successful treatment of a patient with Reiter's syndrome and acquired immunodeficiency syndrome using etretinate. Journal of the American Academy of Dermatology, 20 (5 Pt 2) , 898-903More Information

Breneman, D L; Lucky, A W; Ostrow, R S; Faras, A J; Volger, C; Jenski, L J  (1985). Bowenoid papulosis of the genitalia associated with human papillomavirus DNA type 16 in an infant with atopic dermatitis. Pediatric dermatology, 2 (4) , 297-301

Dermatology,Clinical Research,Dermatopharmacology,Mycosis Fungoide,Cutaneous Lymphoma