Debra Breneman

Debra Lynn Breneman , MD

Adjunct Associate Professor

Medical Sciences Building


COM Dermatology - 0592


Bachelor's Degree: Iowa State University Ames, IA, 1977 (Dual Majors Zoology and Psychology; Minor in Chemistry)

Doctor of Medicine: University of Iowa Iowa City, IA, 1981

Dermatology Residency: University of Cincinnati Medical Center Cincinnati, OH, 1985


American Board of Dermatology (Certification Date: 11-04-1985 )

Clinical Interests


Cutaneous B-cell lymphoma

Cutaneous Lymphoma

Cutaneous T-cell lymphoma

Pruritus (Itchy skin)



Research and Practice Interests

My research interests are in 2 areas:dermato pharmacology;urtaneous lymphomas.Dermatopharmacology:conducting clinical research trials to evaluate the efficacy and safety of various drugs in the treatment of dermatologic diseases.Cutaneous lymphomas:evaluation and treatment of patients with cutaneous lymphomas including B-cell lymphomas including B-cell lymphomas, mycoses fungaide and other cutaneous T-cell lymphoma, and miscellaneous types of cutaneous lymphomas as well as conducting clinical research in this area.

Research Support

Grant: #HS0005 Investigators:Breneman, Debra 12-01-2021 -11-30-2024 Parexel International, LLC A Phase 3, Open-label, parallel group, multicenter, extension study evaluating the long-term treatment of bimekizumab in study participants with moderate to severe hidradenitis suppurativa Role:PI 522345.00 Hold Level:Industry

Grant: #LP0190-1488 Investigators:Breneman, Debra 09-01-2021 -08-31-2024 LEO Pharma A phase 2 trial to evaluate the efficacy and safety of orally-administered LEO 152020 compared with placebo during a 16-week treatment period in adults with moderate to severe atopic dermatitis Role:PI 220313.16 Hold Level:Industry

Grant: #CBI_2022_MF_DevVal_001 Investigators:Breneman, Debra 05-29-2023 -05-28-2026 Castle Biosciences, Inc. Development and Validation of an Ancillary Diagnostic Test for Mycosis Fungoides (SIGNAL-MF) Role:PI 0.00 Hold Level:Industry

Grant: #230LE301 Investigators:Breneman, Debra 05-29-2023 -05-28-2026 IQVIA Clinical Trial Payments A Phase 2/3 Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of BIIB059 in Participants with Active Cutaneous Lupus Erythematosus with or without Sys Role:PI 0.00 Hold Level:Industry

Grant: #INCB 54707-301 Investigators:Breneman, Debra 06-14-2023 -03-12-2026 Incyte Corporation A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Efficacy and Safety Study of Povorcitinib (INCB054707) in Participants With Moderate to Severe Hidradenitis Suppurativa(STOP-HS1) Role:PI 325877.00 Hold Level:Industry


Peer Reviewed Publications

Edinger, James T; Lorenzo, Cynthia R; Breneman, Debra L; Swerdlow, Steven H (2011. ) Primary cutaneous marginal zone lymphoma with subclinical cutaneous involvement and biclonality.Journal of cutaneous pathology, , 38 (9 ) ,724-30 More Information

Breneman, Debra L; Storer, Timothy J; Breneman, John C; Mutasim, Diya F (2008. ) Methotrexate-induced cutaneous ulceration in patients with erythrodermic mycosis fungoides.Therapeutics and clinical risk management, , 4 (5 ) ,1135-41 More Information

Breneman, Debra L; Raju, Uma S; Breneman, John C; Steele, Paul E; McFadden, David W; Cualing, Hernani D; Nussbaum, Michael S; Swerdlow, Steven H (2003. ) Lymph node grading for staging of mycosis fungoides may benefit from examination of multiple excised lymph nodes.Journal of the American Academy of Dermatology, , 48 (5 ) ,702-6 More Information

Kulow, Brittain F; Cualing, Hernani; Steele, Paul; VanHorn, Judi; Breneman, John C; Mutasim, Diya F; Breneman, Debra L Progression of cutaneous B-cell pseudolymphoma to cutaneous B-cell lymphoma.Journal of cutaneous medicine and surgery, , 6 (6 ) ,519-28 More Information

Breneman, D L; Hanifin, J M; Berge, C A; Keswick, B H; Neumann, P B (2000. ) The effect of antibacterial soap with 1.5% triclocarban on Staphylococcus aureus in patients with atopic dermatitis. Cutis, , 66 (4 ) ,296-300

Adamick, C M; Breneman, D L (2000. ) Diffuse and progressive papules and nodules. Archives of dermatology, , 136 (6 ) ,793, 796

Adamick, ; Breneman, (2000. ) Off-Center Fold: Diffuse and Progressive Papules and Nodules. Archives of dermatology, , 136 (6 ) ,791-796

Berberian, B J; Breneman, D L; Drake, L A; Gratton, D; Raimir, S S; Phillips, S; Sulica, V I; Bernstein, J E (1999. ) The addition of topical doxepin to corticosteroid therapy: an improved treatment regimen for atopic dermatitis.International journal of dermatology, , 38 (2 ) ,145-8 More Information

Lebwohl, M G; Breneman, D L; Goffe, B S; Grossman, J R; Ling, M R; Milbauer, J; Pincus, S H; Sibbald, R G; Swinyer, L J; Weinstein, G D; Lew-Kaya, D A; Lue, J C; Gibson, J R; Sefton, J (1998. ) Tazarotene 0.1% gel plus corticosteroid cream in the treatment of plaque psoriasis.Journal of the American Academy of Dermatology, , 39 (4 Pt 1 ) ,590-6 More Information

Ploysangam, T; Breneman, D L; Mutasim, D F (1998. ) Cutaneous pseudolymphomas.Journal of the American Academy of Dermatology, , 38 (6 Pt 1 ) ,877-95; quiz 896-7 More Information

Koo, J; Cuffie, C A; Tanner, D J; Bressinck, R; Cornell, R C; DeVillez, R L; Edwards, L; Breneman, D L; Piacquadio, D J; Guzzo, C A; Monroe, E W Mometasone furoate 0.1%-salicylic acid 5% ointment versus mometasone furoate 0.1% ointment in the treatment of moderate-to-severe psoriasis: a multicenter study. Clinical therapeutics, , 20 (2 ) ,283-91

Breneman, D L; Stewart, D; Hevia, O; Hino, P D; Drake, L A (1998. ) A double-blind, multicenter clinical trial comparing efficacy of once-daily metronidazole 1 percent cream to vehicle in patients with rosacea. Cutis, , 61 (1 ) ,44-7

Breneman, D L (1996. ) Cetirizine versus hydroxyzine and placebo in chronic idiopathic urticaria.The Annals of pharmacotherapy, , 30 (10 ) ,1075-9 More Information

Breneman, D L (1996. ) Evaluation of cutaneous lymphomas. Comprehensive therapy, , 22 (3 ) ,169-74

Fivenson, D P; Breneman, D L; Rosen, G B; Hersh, C S; Cardone, S; Mutasim, D (1994. ) Nicotinamide and tetracycline therapy of bullous pemphigoid. Archives of dermatology, , 130 (6 ) ,753-8

Goldschmidt, H; Breneman, J C; Breneman, D L (1994. ) Ionizing radiation therapy in dermatology.Journal of the American Academy of Dermatology, , 30 (2 Pt 1 ) ,157-82; quiz 183-6 More Information

Breneman, D L; Breneman, J C (1993. ) Cutaneous T-cell lymphoma mimicking porokeratosis of Mibelli.Journal of the American Academy of Dermatology, , 29 (6 ) ,1046-8 More Information

Doebbeling, B N; Breneman, D L; Neu, H C; Aly, R; Yangco, B G; Holley, H P; Marsh, R J; Pfaller, M A; McGowan, J E; Scully, B E (1993. ) Elimination of Staphylococcus aureus nasal carriage in health care workers: analysis of six clinical trials with calcium mupirocin ointment. The Mupirocin Collaborative Study Group.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, , 17 (3 ) ,466-74 More Information

Breneman, D L; Ariano, M C (1993. ) Successful treatment of acne vulgaris in women with a new topical sodium sulfacetamide/sulfur lotion.International journal of dermatology, , 32 (5 ) ,365-7 More Information

Foss, F M; Ihde, D C; Breneman, D L; Phelps, R M; Fischmann, A B; Schechter, G P; Linnoila, I; Breneman, J C; Cotelingam, J D; Ghosh, B C (1992. ) Phase II study of pentostatin and intermittent high-dose recombinant interferon alfa-2a in advanced mycosis fungoides/Sézary syndrome.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 10 (12 ) ,1907-13 More Information

Breneman, D L; Cardone, J S; Blumsack, R F; Lather, R M; Searle, E A; Pollack, V E (1992. ) Topical capsaicin for treatment of hemodialysis-related pruritus.Journal of the American Academy of Dermatology, , 26 (1 ) ,91-4 More Information

Smith, E B; Breneman, D L; Griffith, R F; Hebert, A A; Hickman, J G; Maloney, J M; Millikan, L E; Sulica, V I; Dromgoole, S H; Sefton, J (1992. ) Double-blind comparison of naftifine cream and clotrimazole/betamethasone dipropionate cream in the treatment of tinea pedis.Journal of the American Academy of Dermatology, , 26 (1 ) ,125-7 More Information

Breneman, D L; Nartker, A L; Ballman, E A; Pruemer, J M; Blumsack, R F; Davis, M; Breneman, J C (1991. ) Topical mechlorethamine in the treatment of mycosis fungoides. Uniformity of application and potential for environmental contamination.Journal of the American Academy of Dermatology, , 25 (6 Pt 1 ) ,1059-64 More Information

Kleier, R S; Breneman, D L; Boiko, S (1991. ) Generalized pustulation as a manifestation of the anticonvulsant hypersensitivity syndrome. Archives of dermatology, , 127 (9 ) ,1361-4

Supapannachart, N; Breneman, D L; Linnemann, C C (1991. ) Isolation of human immunodeficiency virus type 1 in cutaneous blister fluid. Archives of dermatology, , 127 (8 ) ,1198-200

Robinson, M K; Parsell, K W; Breneman, D L; Cruze, C A (1991. ) Evaluation of the primary skin irritation and allergic contact sensitization potential of transdermal triprolidine. Fundamental and applied toxicology : official journal of the Society of Toxicology, , 17 (1 ) ,103-19

Fivenson, D P; Breneman, D L; Wander, A H (1990. ) Kaposi's varicelliform eruption. Absence of ocular involvement. Archives of dermatology, , 126 (8 ) ,1037-9

Breneman, D L (1990. ) Use of mupirocin ointment in the treatment of secondarily infected dermatoses.Journal of the American Academy of Dermatology, , 22 (5 Pt 1 ) ,886-92 More Information

Fivenson, D P; Breneman, D L (1989. ) A rapidly progressive papulovesicular eruption. Eczema herpeticum/Kaposi's varicelliform eruption.Archives of dermatology, , 125 (11 ) ,1570, 1572-3 More Information

Fivenson, D P; Crump, G; Scheele, P; Breneman, D L (1989. ) Systemic lupus erythematosus developing in a patient with longstanding pulmonary sarcoidosis. The Journal of rheumatology, , 16 (8 ) ,1116-9

Belz, J; Breneman, D L; Nordlund, J J; Solinger, A (1989. ) Successful treatment of a patient with Reiter's syndrome and acquired immunodeficiency syndrome using etretinate.Journal of the American Academy of Dermatology, , 20 (5 Pt 2 ) ,898-903 More Information

Breneman, D L; Lucky, A W; Ostrow, R S; Faras, A J; Volger, C; Jenski, L J (1985. ) Bowenoid papulosis of the genitalia associated with human papillomavirus DNA type 16 in an infant with atopic dermatitis. Pediatric dermatology, , 2 (4 ) ,297-301


Dermatology,Clinical Research,Dermatopharmacology,Mycosis Fungoide,Cutaneous Lymphoma