John C Breneman , MD

John Breneman Professor of Radiation Oncology and Neurosurgery, specializes in pediatric cancers, and tumors of the central nervous system, including the use of stereotactic radiosurgery and other highly conformal radiation techniques

Bachelor's Degree: Illinois Institute of Technology Chicago, IL, 1977 (Physics)

Medical Degree: University of Iowa School of Medicine Iowa City, IA, 1981

Internship: Butterworth Hospital Grand Rapids, MI, 1982 (Internal Medicine)

Residency: University of Cincinnati Cincinnati, OH, 1985 (Radiation Oncology)

American Board of Radiology (Therapeutic Radiology) (Certification Date: 06-06-1985 )

Neurological Complications of Cancer

Radiation Oncology

Acute Lymphocytic Leukemia

Acute Myeloid Leukemia

Adenocarcinoma

Adenosquamous Carcinoma

Advanced Skin Cancer

Basal Cell Carcinoma

Basosquamous Carcinoma

Bowen's Disease

Brain Cancers

Brain Metastases

Brain Stem Tumor

Brain Tumor

Cancer

Central Nervous System Tumors

Cerebellar Cancers

Cerebral Arterial Disease

Cerebral Contusion

Cerebral Hemorrhage

Cerebral Palsy

Cerebral Small Vessel Disease

Cerebral Ventricle Tumor

Chondrosarcoma

Chordoma

Cutaneous B-cell lymphoma

Cutaneous Lymphoma

Cutaneous Melanoma

Cutaneous T-cell lymphoma

Dermatofibrosarcoma Protuberans (DFSP)

Eccrine Porocarcinoma

Ependymoblastoma

Ewing Sarcoma

Ganglioneuroblastoma

Glioma

Glioneuronal Tumor

Gliosarcoma

Hypothalamic Cancers

Infratentorial Cancers

Leptomeningeal Disease

Liposarcoma

Medulloblastoma

Meningeal Cancers

Meningeal Carcinomatosis

Metastasis Cancers

Metastatic Brain Tumor

Mucoepidermoid Carcinoma

Neoplasm

Nerve Sheath Tumors

Nerve Tumors

Neurilemmoma

Neuroblastoma

Neurocytoma

Neurofibrosarcoma

Nonmelanoma Skin Cancer

Olfactory Neuroblastoma (Esthesioneuroblastoma)

Oligodendroglioma

Osteogenic Sarcoma (Osteosarcoma)

Pineoblastoma

Plexiform Neurofibroma

Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Primary Central Nervous System (CNS) Lymphoma

Primitive Neuroectodermal Tumors

Retinoblastoma

Rhabdomyosarcoma

Sebaceous Carcinoma

Skin Cancer

Skin Cancer Melanoma

Skull-Base Tumors

Spinal Arteriovenous Malformation (AVM)

Spinal Cancers

Triple Negative Breast Cancer

Tubular Carcinoma

Pediatric and Neuro Oncology, Proton therapy

Grant: #15500 / U10-CA-98543 Investigators:Breneman, John 03-01-2003 -02-28-2010 National Cancer Institute Children's Oncology Clinical Trial Role:PI $33,002.00 Closed Level:Federal

Grant: #5-U10-CA-024507-26-A0-S0-E0 Investigators:Breneman, John 03-01-2000 -02-28-2003 National Cancer Institute Intergroup Rhabdomyosarcoma Study Role:PI $30,850.00 Closed Level:Federal

Grant: #5-U10-CA-24507-22-A0-S0-E0 Investigators:Breneman, John 07-01-1998 -12-31-1999 National Cancer Institute Intergroup Rhabdomyosarcoma Study Role:PI $10,923.00 Closed Level:Federal

Grant: #19865 Amd 1 Investigators:Breneman, John 03-01-2010 -02-28-2011 National Cancer Institute CureSearch Phase III Clinical Trials Role:PI $1,500.00 Closed Level:Federal

Grant: #AR71096 (U10CA180886) Investigators:Breneman, John 03-01-2023 -02-28-2025 Public Health Institute Radiation Oncology Central Review for COG NCTN Trials Role:PI 1500.00 Hold Level:Non Profit

Peer Reviewed Publications

Arndt, Carola A S; Stoner, Julie A; Hawkins, Douglas S; Rodeberg, David A; Hayes-Jordan, Andrea A; Paidas, Charles N; Parham, David M; Teot, Lisa A; Wharam, Moody D; Breneman, John C; Donaldson, Sarah S; Anderson, James R; Meyer, William H (2009. ) Vincristine, actinomycin, and cyclophosphamide compared with vincristine, actinomycin, and cyclophosphamide alternating with vincristine, topotecan, and cyclophosphamide for intermediate-risk rhabdomyosarcoma: children's oncology group study D9803.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 27 (31 ) ,5182-8 More Information

Blonigen, Brian J; Steinmetz, Ryan D; Levin, Linda; Lamba, Michael A; Warnick, Ronald E; Breneman, John C (2009. ) Irradiated Volume as a Predictor of Brain Radionecrosis after Linear Accelerator Stereotactic Radiosurgery.International journal of radiation oncology, biology, physics, , More Information

Lamba, Michael; Breneman, John C; Warnick, Ronald E (2009. ) Evaluation of image-guided positioning for frameless intracranial radiosurgery.International journal of radiation oncology, biology, physics, , 74 (3 ) ,913-9 More Information

Breneman, John C; Steinmetz, Ryan; Smith, Aaron; Lamba, Michael; Warnick, Ronald E (2009. ) Frameless image-guided intracranial stereotactic radiosurgery: clinical outcomes for brain metastases.International journal of radiation oncology, biology, physics, , 74 (3 ) ,702-6 More Information

Petr, Michael J; McPherson, Christopher M; Breneman, John C; Warnick, Ronald E (2009. ) Management of newly diagnosed single brain metastasis with surgical resection and permanent I-125 seeds without upfront whole brain radiotherapy.Journal of neuro-oncology, , 92 (3 ) ,393-400 More Information

Breneman, Debra L; Storer, Timothy J; Breneman, John C; Mutasim, Diya F (2008. ) Methotrexate-induced cutaneous ulceration in patients with erythrodermic mycosis fungoides. Therapeutics and clinical risk management, , 4 (5 ) ,1135-41

Darakchiev, Borimir J; Albright, Robert E; Breneman, John C; Warnick, Ronald E (2008. ) Safety and efficacy of permanent iodine-125 seed implants and carmustine wafers in patients with recurrent glioblastoma multiforme.Journal of neurosurgery, , 108 (2 ) ,236-42 More Information

Dagnew, Elias; Kanski, Jeffrey; McDermott, Michael W; Sneed, Penny K; McPherson, Christopher; Breneman, John C; Warnick, Ronald E (2007. ) Management of newly diagnosed single brain metastasis using resection and permanent iodine-125 seeds without initial whole-brain radiotherapy: a two institution experience. Neurosurgical focus, , 22 (3 ) ,E3

Gaynon, Paul S; Harris, Richard E; Altman, Arnold J; Bostrom, Bruce C; Breneman, John C; Hawks, Ria; Steele, David; Zipf, Theodore; Stram, Daniel O; Villaluna, Doodjuen; Trigg, Michael E (2006. ) Bone marrow transplantation versus prolonged intensive chemotherapy for children with acute lymphoblastic leukemia and an initial bone marrow relapse within 12 months of the completion of primary therapy: Children's Oncology Group study CCG-1941.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 24 (19 ) ,3150-6 More Information

Warnick, Ronald E; Darakchiev, Borimir J; Breneman, John C Stereotactic radiosurgery for patients with solid brain metastases: current status. Journal of neuro-oncology, , 69 (1-3 ) ,125-37

Michalski, Jeff M; Meza, Jane; Breneman, John C; Wolden, Suzanne L; Laurie, Fran; Jodoin, MaryAnn; Raney, Beverly; Wharam, Moody D; Donaldson, Sarah S (2004. ) Influence of radiation therapy parameters on outcome in children treated with radiation therapy for localized parameningeal rhabdomyosarcoma in Intergroup Rhabdomyosarcoma Study Group trials II through IV.International journal of radiation oncology, biology, physics, , 59 (4 ) ,1027-38 More Information

Augsburger, James J; Schneider, Susan; Narayana, Ashwatha; Breneman, John C; Aron, Bernard S; Barrett, William L; Trichopoulos, Nikolaos (2004. ) Plaque radiotherapy for choroidal and ciliochoroidal melanomas with limited nodular extrascleral extension. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, , 39 (4 ) ,380-7

Abdel-Aziz, Khaled M; Froelich, Sebastien C; Dagnew, Elias; Jean, Walter; Breneman, John C; Zuccarello, Mario; van Loveren, Harry R; Tew, John M (2004. ) Large sphenoid wing meningiomas involving the cavernous sinus: conservative surgical strategies for better functional outcomes. Neurosurgery, , 54 (6 ) ,1375-83; discussion

Wharam, Moody D; Meza, Jane; Anderson, James; Breneman, John C; Donaldson, Sarah S; Fitzgerald, Thomas J; Michalski, Jeff; Teot, Lisa A; Wiener, Eugene S; Meyer, William H (2004. ) Failure pattern and factors predictive of local failure in rhabdomyosarcoma: a report of group III patients on the third Intergroup Rhabdomyosarcoma Study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 22 (10 ) ,1902-8 More Information

Breneman, Debra L; Raju, Uma S; Breneman, John C; Steele, Paul E; McFadden, David W; Cualing, Hernani D; Nussbaum, Michael S; Swerdlow, Steven H (2003. ) Lymph node grading for staging of mycosis fungoides may benefit from examination of multiple excised lymph nodes.Journal of the American Academy of Dermatology, , 48 (5 ) ,702-6 More Information

Breneman, John C; Lyden, Elizabeth; Pappo, Alberto S; Link, Michael P; Anderson, James R; Parham, David M; Qualman, Stephen J; Wharam, Moody D; Donaldson, Sarah S; Maurer, Harold M; Meyer, William H; Baker, K Scott; Paidas, Charles N; Crist, William M (2003. ) Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma--a report from the Intergroup Rhabdomyosarcoma Study IV. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 21 (1 ) ,78-84

Kulow, Brittain F; Cualing, Hernani; Steele, Paul; VanHorn, Judi; Breneman, John C; Mutasim, Diya F; Breneman, Debra L Progression of cutaneous B-cell pseudolymphoma to cutaneous B-cell lymphoma.Journal of cutaneous medicine and surgery, , 6 (6 ) ,519-28 More Information

Link, Michael J; Cohen, Paul L; Breneman, John C; Tew, John M (2002. ) Malignant squamous degeneration of a cerebellopontine angle epidermoid tumor. Case report.Journal of neurosurgery, , 97 (5 ) ,1237-43 More Information

Sneed, Penny K; Suh, John H; Goetsch, Steven J; Sanghavi, Seema N; Chappell, Richard; Buatti, John M; Regine, William F; Weltman, Eduardo; King, Vernon J; Breneman, John C; Sperduto, Paul W; Mehta, Minesh P (2002. ) A multi-institutional review of radiosurgery alone vs. radiosurgery with whole brain radiotherapy as the initial management of brain metastases. International journal of radiation oncology, biology, physics, , 53 (3 ) ,519-26

Raney, Richard Beverly; Meza, Jane; Anderson, James R; Fryer, Christopher J; Donaldson, Sarah S; Breneman, John C; Fitzgerald, Thomas J; Gehan, Edmund A; Michalski, Jeff M; Ortega, Jorge A; Qualman, Stephen J; Sandler, Eric; Wharam, Moody D; Wiener, Eugene S; Maurer, Harold M; Crist, William M (2002. ) Treatment of children and adolescents with localized parameningeal sarcoma: experience of the Intergroup Rhabdomyosarcoma Study Group protocols IRS-II through -IV, 1978-1997. Medical and pediatric oncology, , 38 (1 ) ,22-32

Donaldson, S S; Meza, J; Breneman, J C; Crist, W M; Laurie, F; Qualman, S J; Wharam, M (2001. ) Results from the IRS-IV randomized trial of hyperfractionated radiotherapy in children with rhabdomyosarcoma--a report from the IRSG. International journal of radiation oncology, biology, physics, , 51 (3 ) ,718-28

Smith, L M; Anderson, J R; Qualman, S J; Crist, W M; Paidas, C N; Teot, L A; Pappo, A S; Link, M P; Grier, H E; Wiener, E S; Breneman, J C; Raney, R B; Maurer, H M; Donaldson, S S (2001. ) Which patients with microscopic disease and rhabdomyosarcoma experience relapse after therapy? A report from the soft tissue sarcoma committee of the children's oncology group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 19 (20 ) ,4058-64

Sanghavi, S N; Miranpuri, S S; Chappell, R; Buatti, J M; Sneed, P K; Suh, J H; Regine, W F; Weltman, E; King, V J; Goetsch, S J; Breneman, J C; Sperduto, P W; Scott, C; Mabanta, S; Mehta, M P (2001. ) Radiosurgery for patients with brain metastases: a multi-institutional analysis, stratified by the RTOG recursive partitioning analysis method. International journal of radiation oncology, biology, physics, , 51 (2 ) ,426-34

Spunt, S L; Anderson, J R; Teot, L A; Breneman, J C; Meyer, W H; Pappo, A S (2001. ) Routine brain imaging is unwarranted in asymptomatic patients with rhabdomyosarcoma arising outside of the head and neck region that is metastatic at diagnosis: a report from the Intergroup Rhabdomyosarcoma Study Group. Cancer, , 92 (1 ) ,121-5

Barrett, W L; Aron, B S; Breneman, J C; Narayana, A; Redmond, K P (2001. ) Clinical oncology clerkship for third-year medical students. Journal of cancer education : the official journal of the American Association for Cancer Education, , 16 (4 ) ,182-4

Breneman, J C; Wiener, E S (2000. ) Issues in the local control of rhabdomyosarcoma. Medical and pediatric oncology, , 35 (2 ) ,104-9

Baker, K S; Anderson, J R; Link, M P; Grier, H E; Qualman, S J; Maurer, H M; Breneman, J C; Wiener, E S; Crist, W M (2000. ) Benefit of intensified therapy for patients with local or regional embryonal rhabdomyosarcoma: results from the Intergroup Rhabdomyosarcoma Study IV. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 18 (12 ) ,2427-34

Patel, S; Breneman, J C; Warnick, R E; Albright, R E; Tobler, W D; van Loveren, H R; Tew, J M (2000. ) Permanent iodine-125 interstitial implants for the treatment of recurrent glioblastoma multiforme. Neurosurgery, , 46 (5 ) ,1123-8; discussion 1

Wolden, S L; Anderson, J R; Crist, W M; Breneman, J C; Wharam, M D; Wiener, E S; Qualman, S J; Donaldson, S S (1999. ) Indications for radiotherapy and chemotherapy after complete resection in rhabdomyosarcoma: A report from the Intergroup Rhabdomyosarcoma Studies I to III. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 17 (11 ) ,3468-75

Beech, T R; Moss, R L; Anderson, J A; Maurer, H M; Qualman, S J; Breneman, J C; Wiener, E S; Crist, W M (1999. ) What comprises appropriate therapy for children/adolescents with rhabdomyosarcoma arising in the abdominal wall? A report from the Intergroup Rhabdomyosarcoma Study Group. Journal of pediatric surgery, , 34 (5 ) ,668-71

Fodor, J; Breneman, J C; Lamba, M A; Foster, A E; Elson, H (1998. ) Modification of a linear accelerator table top for non-coplanar conformal brain radiotherapy. Medical dosimetry : official journal of the American Association of Medical Dosimetrists, , 23 (1 ) ,27-9

Steinherz, P G; Gaynon, P S; Breneman, J C; Cherlow, J M; Grossman, N J; Kersey, J H; Johnstone, H S; Sather, H N; Trigg, M E; Uckun, F M; Bleyer, W A (1998. ) Treatment of patients with acute lymphoblastic leukemia with bulky extramedullary disease and T-cell phenotype or other poor prognostic features: randomized controlled trial from the Children's Cancer Group. Cancer, , 82 (3 ) ,600-12

Breneman, (1997. ) Genitourinary Rhabdomyosarcoma.Seminars in radiation oncology, , 7 (3 ) ,217-224 More Information

Breneman, J C; Warnick, R E; Albright, R E; Kukiatinant, N; Shaw, J; Armin, D; Tew, J (1997. ) Stereotactic radiosurgery for the treatment of brain metastases. Results of a single institution series. Cancer, , 79 (3 ) ,551-7

Raney, R B; Asmar, L; Newton, W A; Bagwell, C; Breneman, J C; Crist, W; Gehan, E A; Webber, B; Wharam, M; Wiener, E S; Anderson, J R; Maurer, H M (1997. ) Ewing's sarcoma of soft tissues in childhood: a report from the Intergroup Rhabdomyosarcoma Study, 1972 to 1991. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 15 (2 ) ,574-82

Lobe, T E; Wiener, E; Andrassy, R J; Bagwell, C E; Hays, D; Crist, W M; Webber, B; Breneman, J C; Reed, M M; Tefft, M C; Heyn, R (1996. ) The argument for conservative, delayed surgery in the management of prostatic rhabdomyosarcoma. Journal of pediatric surgery, , 31 (8 ) ,1084-7

Steinherz, P G; Gaynon, P S; Breneman, J C; Cherlow, J M; Grossman, N J; Kersey, J H; Johnstone, H S; Sather, H N; Trigg, M E; Chappell, R; Hammond, D; Bleyer, W A (1996. ) Cytoreduction and prognosis in acute lymphoblastic leukemia--the importance of early marrow response: report from the Childrens Cancer Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 14 (2 ) ,389-98

Taha, J M; Lamba, M A; Samaratunga, C; Breneman, J C; Warnick, R E (1996. ) A method to reduce systematic spatial shift associated with magnetic resonance imaging. Stereotactic and functional neurosurgery, , 66 (1-3 ) ,118-22

Tomsick, T A; Ernst, R J; Tew, J M; Brott, T G; Breneman, J C (1995. ) Adult choroidal vein of Galen malformation. AJNR. American journal of neuroradiology, , 16 (4 Suppl ) ,861-5

Goldschmidt, H; Breneman, J C; Breneman, D L (1994. ) Ionizing radiation therapy in dermatology. Journal of the American Academy of Dermatology, , 30 (2 Pt 1 ) ,157-82; quiz 183-6

Cherlow, J M; Steinherz, P G; Sather, H N; Gaynon, P S; Grossman, N J; Kersey, J H; Johnstone, H S; Breneman, J C; Trigg, M E; Hammond, G D (1993. ) The role of radiation therapy in the treatment of acute lymphoblastic leukemia with lymphomatous presentation: a report from the Childrens Cancer Group. International journal of radiation oncology, biology, physics, , 27 (5 ) ,1001-9

Breneman, D L; Breneman, J C (1993. ) Cutaneous T-cell lymphoma mimicking porokeratosis of Mibelli. Journal of the American Academy of Dermatology, , 29 (6 ) ,1046-8

Sawaya, R; Breneman, J C (1993. ) Design of a cap for radioshielding during treatment with interstitial 125I brain implants. Journal of neuro-oncology, , 16 (3 ) ,233-4

Foss, F M; Ihde, D C; Breneman, D L; Phelps, R M; Fischmann, A B; Schechter, G P; Linnoila, I; Breneman, J C; Cotelingam, J D; Ghosh, B C (1992. ) Phase II study of pentostatin and intermittent high-dose recombinant interferon alfa-2a in advanced mycosis fungoides/Sézary syndrome. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 10 (12 ) ,1907-13

Breneman, D L; Nartker, A L; Ballman, E A; Pruemer, J M; Blumsack, R F; Davis, M; Breneman, J C (1991. ) Topical mechlorethamine in the treatment of mycosis fungoides. Uniformity of application and potential for environmental contamination. Journal of the American Academy of Dermatology, , 25 (6 Pt 1 ) ,1059-64

Breneman, J C (1991. ) Irradiation of epithelial skin cancer. International journal of radiation oncology, biology, physics, , 21 (5 ) ,1393

Breneman, J C; Mitchell, S E; Hawley, D K; Aron, B S; Schroder, L E (1991. ) Concurrent radiotherapy and chemotherapy for locally advanced non-small-cell cancer of the lung. Report of a clinical trial and review of the literature. American journal of clinical oncology, , 14 (1 ) ,9-15

Breneman, J C; Elson, H R; Little, R; Lamba, M; Foster, A E; Aron, B S (1990. ) A technique for delivery of total body irradiation for bone marrow transplantation in adults and adolescents. International journal of radiation oncology, biology, physics, , 18 (5 ) ,1233-6

Margolin, S G; Breneman, J C; Denman, D L; LaChapelle, P; Weckbach, L; Aron, B S (1990. ) Management of radiation-induced moist skin desquamation using hydrocolloid dressing. Cancer nursing, , 13 (2 ) ,71-80

VanAken, M L; Breneman, J C; Elson, H R; Foster, A E; Lukes, S J; Little, R (1988. ) Incorporation of patient immobilization, tissue compensation and matchline junction technique for three-field breast treatment. Medical dosimetry : official journal of the American Association of Medical Dosimetrists, , 13 (3 ) ,131-5

Breneman, J C; Bradshaw, A; Gluckman, J; Aron, B S (1988. ) Prevention of stomal recurrence in patients requiring emergency tracheostomy for advanced laryngeal and pharyngeal tumors. Cancer, , 62 (4 ) ,802-5

Denman, D L; Foster, A E; Lewis, G C; Redmond, K P; Elson, H R; Breneman, J C; Kereiakes, J G; Aron, B S (1988. ) The distribution of power and heat produced by interstitial microwave antenna arrays: II. The role of antenna spacing and insertion depth. International journal of radiation oncology, biology, physics, , 14 (3 ) ,537-45

Denman, D L; Elson, H R; Lewis, G C; Breneman, J C; Clausen, C L; Dine, J; Aron, B S (1988. ) The distribution of power and heat produced by interstitial microwave antenna arrays: I. Comparative phantom and canine studies. International journal of radiation oncology, biology, physics, , 14 (1 ) ,127-37

Raney, Beverly; Anderson, James; Breneman, John; Donaldson, Sarah S; Huh, Winston; Maurer, Harold; Michalski, Jeff; Qualman, Stephen; Ullrich, Fred; Wharam, Moody; Meyer, William (2008. ) Results in patients with cranial parameningeal sarcoma and metastases (Stage 4) treated on Intergroup Rhabdomyosarcoma Study Group (IRSG) Protocols II-IV, 1978-1997: report from the Children's Oncology Group.Pediatric blood & cancer, , 51 (1 ) ,17-22 More Information

Jarrar, Mohammad; Gaynon, Paul S; Periclou, Antonia P; Fu, Cecilia; Harris, Richard E; Stram, Daniel; Altman, Arnold; Bostrom, Bruce; Breneman, John; Steele, David; Trigg, Michael; Zipf, Theodore; Avramis, Vassilios I (2006. ) Asparagine depletion after pegylated E. coli asparaginase treatment and induction outcome in children with acute lymphoblastic leukemia in first bone marrow relapse: a Children's Oncology Group study (CCG-1941).Pediatric blood & cancer, , 47 (2 ) ,141-6 More Information

Rodeberg, David; Arndt, Carola; Breneman, John; Lyden, Elizabeth; Donaldson, Sarah; Paidas, Charles; Andrassy, Richard; Meyer, William; Wiener, Eugene (2005. ) Characteristics and outcomes of rhabdomyosarcoma patients with isolated lung metastases from IRS-IV.Journal of pediatric surgery, , 40 (1 ) ,256-62 More Information

Joshi, D; Anderson, James R; Paidas, C; Breneman, J; Parham, D M; Crist, W (2004. ) Age is an independent prognostic factor in rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.Pediatric blood & cancer, , 42 (1 ) ,64-73 More Information

Glod, John; Koch, Bernadette; Myseros, John; Breneman, John; Collins, Margaret H (2002. ) Issues concerning the treatment of a child with a craniopharyngioma.Medical and pediatric oncology, , 38 (5 ) ,360-7 More Information

Crist, W M; Anderson, J R; Meza, J L; Fryer, C; Raney, R B; Ruymann, F B; Breneman, J; Qualman, S J; Wiener, E; Wharam, M; Lobe, T; Webber, B; Maurer, H M; Donaldson, S S (2001. ) Intergroup rhabdomyosarcoma study-IV: results for patients with nonmetastatic disease. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 19 (12 ) ,3091-102

Pappo, A S; Lyden, E; Breneman, J; Wiener, E; Teot, L; Meza, J; Crist, W; Vietti, T (2001. ) Up-front window trial of topotecan in previously untreated children and adolescents with metastatic rhabdomyosarcoma: an intergroup rhabdomyosarcoma study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 19 (1 ) ,213-9

Moyer, P D; Golnik, K C; Breneman, J (2000. ) Treatment of optic nerve sheath meningioma with three-dimensional conformal radiation. American journal of ophthalmology, , 129 (5 ) ,694-6

Wharam, M D; Hanfelt, J J; Tefft, M C; Johnston, J; Ensign, L G; Breneman, J; Donaldson, S S; Fryer, C; Gehan, E A; Raney, R B; Maurer, H M (1997. ) Radiation therapy for rhabdomyosarcoma: local failure risk for Clinical Group III patients on Intergroup Rhabdomyosarcoma Study II. International journal of radiation oncology, biology, physics, , 38 (4 ) ,797-804

Arndt, C; Tefft, M; Gehan, E; Anderson, J; Jenson, M; Link, M; Donaldson, S; Breneman, J; Wiener, E; Webber, B; Maurer, H A feasibility, toxicity, and early response study of etoposide, ifosfamide, and vincristine for the treatment of children with rhabdomyosarcoma: a report from the Intergroup Rhabdomyosarcoma Study (IRS) IV pilot study. Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology, , 19 (2 ) ,124-9

Donaldson, S S; Asmar, L; Breneman, J; Fryer, C; Glicksman, A S; Laurie, F; Wharam, M; Gehan, E A (1995. ) Hyperfractionated radiation in children with rhabdomyosarcoma--results of an Intergroup Rhabdomyosarcoma Pilot Study. International journal of radiation oncology, biology, physics, , 32 (4 ) ,903-11

Breneman, J; Breneman, D (1995. ) Response to total skin irradiation for mycosis fungoides associated with lymphomatoid papulosis: regarding Wilson et al. International journal of radiation oncology, biology, physics, , 28 (1 ) ,829

Soltys, Scott G; Kirkpatrick, John P; Laack, Nadia N; Kavanagh, Brian D; Breneman, John C; Shih, Helen A (2015. ) Is Less, More? The Evolving Role of Radiation Therapy for Brain Metastases.International journal of radiation oncology, biology, physics, , 92 (5 ) ,963-6 More Information

Walterhouse, David O; Pappo, Alberto S; Meza, Jane L; Breneman, John C; Hayes-Jordan, Andrea A; Parham, David M; Cripe, Timothy P; Anderson, James R; Meyer, William H; Hawkins, Douglas S (2014. ) Shorter-duration therapy using vincristine, dactinomycin, and lower-dose cyclophosphamide with or without radiotherapy for patients with newly diagnosed low-risk rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 32 (31 ) ,3547-52 More Information

Guarnaschelli, Jess N; Vagal, Achala S; McKenzie, Joshua T; McPherson, Christopher M; Warnick, Ronald E; Batra, Vivek; Breneman, John C; Lamba, Michael A Target definition for malignant gliomas: no difference in radiation treatment volumes between 1.5T and 3T magnetic resonance imaging.Practical radiation oncology, , 4 (5 ) ,e195-201 More Information

Wang, Lily L; Leach, James L; Breneman, John C; McPherson, Christopher M; Gaskill-Shipley, Mary F Critical role of imaging in the neurosurgical and radiotherapeutic management of brain tumors.Radiographics : a review publication of the Radiological Society of North America, Inc, , 34 (3 ) ,702-21 More Information

Ghose, Abhimanyu; Morris, John C; Breneman, John C; Essell, James; Wang, Jiang; Benzaquen, Sadia Medulloblastoma in an Adult With Late Extraneural Metastases to the Mediastinum.Journal of investigative medicine high impact case reports, , 2 (2 ) ,2324709614532798 More Information

McKenzie, Joshua T; Guarnaschelli, Jess N; Vagal, Achala S; Warnick, Ronald E; Breneman, John C (2013. ) Hypofractionated stereotactic radiotherapy for unifocal and multifocal recurrence of malignant gliomas.Journal of neuro-oncology, , 113 (3 ) ,403-9 More Information

McPherson, Christopher M; Gerena-Lewis, Margie; Breneman, John C; Warnick, Ronald E (2012. ) Results of phase I study of a multi-modality treatment for newly diagnosed glioblastoma multiforme using local implantation of concurrent BCNU wafers and permanent I-125 seeds followed by fractionated radiation and temozolomide chemotherapy.Journal of neuro-oncology, , 108 (3 ) ,521-5 More Information

Lin, Chi; Donaldson, Sarah S; Meza, Jane L; Anderson, James R; Lyden, Elizabeth R; Brown, Christopher K; Morano, Karen; Laurie, Fran; Arndt, Carola A; Enke, Charles A; Breneman, John C (2012. ) Effect of radiotherapy techniques (IMRT vs. 3D-CRT) on outcome in patients with intermediate-risk rhabdomyosarcoma enrolled in COG D9803--a report from the Children's Oncology Group.International journal of radiation oncology, biology, physics, , 82 (5 ) ,1764-70 More Information

Weiss, Brian D; Dasgupta, Roshni; Gelfand, Michael J; Laor, Tal; Yin, Hong; Breneman, John C; Lavigne, Ruth; Elluru, Ravindhra G; Wagner, Lars M (2011. ) Use of sentinel node biopsy for staging parameningeal rhabdomyosarcoma.Pediatric blood & cancer, , 57 (3 ) ,520-3 More Information

Walterhouse, David O; Meza, Jane L; Breneman, John C; Donaldson, Sarah S; Hayes-Jordan, Andrea; Pappo, Alberto S; Arndt, Carola; Raney, R Beverly; Meyer, William H; Hawkins, Douglas S (2011. ) Local control and outcome in children with localized vaginal rhabdomyosarcoma: a report from the Soft Tissue Sarcoma committee of the Children's Oncology Group.Pediatric blood & cancer, , 57 (1 ) ,76-83 More Information

Raney, R Beverly; Walterhouse, David O; Meza, Jane L; Andrassy, Richard J; Breneman, John C; Crist, William M; Maurer, Harold M; Meyer, William H; Parham, David M; Anderson, James R (2011. ) Results of the Intergroup Rhabdomyosarcoma Study Group D9602 protocol, using vincristine and dactinomycin with or without cyclophosphamide and radiation therapy, for newly diagnosed patients with low-risk embryonal rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , 29 (10 ) ,1312-8 More Information

Turpin, Brian; Pressey, Joseph G; Nagarajan, Rajaram; Weiss, Brian D; Trout, Andrew T; Gelfand, Michael J; Pater, Luke; Vatner, Ralph E; Breneman, John C; Dasgupta, Roshni (2019. ) Sentinel lymph node biopsy in head and neck rhabdomyosarcoma.Pediatric blood & cancer, , 66 (3 ) ,e27532 More Information

Walterhouse, David O; Barkauskas, Donald A; Hall, David; Ferrari, Andrea; De Salvo, Gian Luca; Koscielniak, Ewa; Stevens, Michael C G; Martelli, Hélène; Seitz, Guido; Rodeberg, David A; Shnorhavorian, Margarett; Dasgupta, Roshni; Breneman, John C; Anderson, James R; Bergeron, Christophe; Bisogno, Gianni; Meyer, William H; Hawkins, Douglas S; Minard-Colin, Veronique (2018. ) Demographic and Treatment Variables Influencing Outcome for Localized Paratesticular Rhabdomyosarcoma: Results From a Pooled Analysis of North American and European Cooperative Groups.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, , JCO2018789388 More Information

Breneman, John C; Donaldson, Sarah S; Constine, Louis; Merchant, Thomas; Marcus, Karen; Paulino, Arnold C; Followill, David; Mahajan, Anita; Laack, Nadia; Esiashvili, Natia; Haas-Kogan, Daphne; Laurie, Fran; Olch, Arthur; Ulin, Kenneth; Hodgson, David; Yock, Torunn I; Terezakis, Stephanie; Krasin, Matt; Panoff, Joseph; Chuba, Paul; Hua, Chia-Ho; Hess, Clayton B; Houghton, Peter J; Wolden, Suzanne; Buchsbaum, Jeff; Fitzgerald, Thomas J; Kalapurakal, John A (2018. ) The Children's Oncology Group Radiation Oncology Discipline: 15 Years of Contributions to the Treatment of Childhood Cancer.International journal of radiation oncology, biology, physics, , 101 (4 ) ,860-874 More Information

Hess, Clayton B; Indelicato, Daniel J; Paulino, Arnold C; Hartsell, William F; Hill-Kayser, Christine E; Perkins, Stephanie M; Mahajan, Anita; Laack, Nadia N; Ermoian, Ralph P; Chang, Andrew L; Wolden, Suzanne L; Mangona, Victor S; Kwok, Young; Breneman, John C; Perentesis, John P; Gallotto, Sara L; Weyman, Elizabeth A; Bajaj, Benjamin V M; Lawell, Miranda P; Yeap, Beow Y; Yock, Torunn I (2018. ) An Update From the Pediatric Proton Consortium Registry.Frontiers in oncology, , 8 ,165 More Information

Minniti, Giuseppe; Soltys, Scott G; Halasz, Lia M; Breneman, John C; Chan, Michael; Laack, Nadia N; Kirkpatrick, John P (2018. ) Stereotactic Radiosurgery for Resected Brain Metastases: New Evidence Supports a Practice Shift, but Questions Remain.International journal of radiation oncology, biology, physics, , 100 (3 ) ,535-538 More Information

Prasad, Rahul N; Breneman, John C; Struve, Timothy; Warnick, Ronald E; Pater, Luke E (2018. ) Linac-based fractionated stereotactic radiosurgery for high-risk meningioma. Journal of radiosurgery and SBRT, , 5 (4 ) ,269-276

Walterhouse, David O; Pappo, Alberto S; Meza, Jane L; Breneman, John C; Hayes-Jordan, Andrea; Parham, David M; Cripe, Timothy P; Anderson, James R; Meyer, William H; Hawkins, Douglas S (2017. ) Reduction of cyclophosphamide dose for patients with subset 2 low-risk rhabdomyosarcoma is associated with an increased risk of recurrence: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.Cancer, , 123 (12 ) ,2368-2375 More Information

Halasz, Lia M; Soltys, Scott G; Breneman, John C; Chan, Michael D; Laack, Nadia N; Minniti, Giuseppe; Kirkpatrick, John P (2017. ) Treatment of Gliomas: A Changing Landscape.International journal of radiation oncology, biology, physics, , 98 (2 ) ,255-258 More Information

Kirkpatrick, John P; Laack, Nadia N; Soltys, Scott G; Halasz, Lia M; Breneman, John C; Shih, Helen A (2016. ) Brain Metastases From Melanoma: Therapy at the Crossroads.International journal of radiation oncology, biology, physics, , 96 (4 ) ,713-716 More Information

Brahimaj, Bledi; Lamba, Michael; Breneman, John C; Warnick, Ronald E (2016. ) Iodine-125 seed migration within brain parenchyma after brachytherapy for brain metastasis: case report.Journal of neurosurgery, , 125 (5 ) ,1167-1170 More Information

Frankart, Andrew J; Breneman, John C; Pater, Luke E (2021. ) Radiation Therapy in the Treatment of Head and Neck Rhabdomyosarcoma.Cancers, , 13 (14 ) , More Information

Lazow, Margot A; Leach, James L; Trout, Andrew T; Breneman, John C; Fouladi, Maryam; Fuller, Christine (2021. ) Extraneural Metastases of Diffuse Midline Glioma, H3 K27M-Mutant at Diagnosis: Case Report, Review of the Literature, and Identifying Targetable Alterations.Journal of pediatric hematology/oncology, , More Information

Tsang, Derek S; Vargo, John Austin; Goddard, Karen; Breneman, John C; Kalapurakal, John A; Marcus, Karen J (2021. ) Palliative radiation therapy for children with cancer.Pediatric blood & cancer, , 68 Suppl 2 ,e28292 More Information

Kalapurakal, John A; Breneman, John C; Janssens, Geert O; Marcus, Karen (2021. ) Introduction to the COG/SIOP/PROS supplement on radiation oncology.Pediatric blood & cancer, , 68 Suppl 2 ,e28768 More Information

Breneman, Debra L; Breneman, Alyssa; Ballman, Elaine; Breneman, John C (2021. ) Long-term effects of total skin electron beam therapy for mycosis fungoides on hair and nail loss and regrowth.The Journal of dermatological treatment, , 1-4 More Information

Holt, Douglas E; Hiniker, Susan M; Kalapurakal, John A; Breneman, John C; Shiao, Jay C; Boik, Nicole; Cooper, Benjamin T; Dorn, Paige L; Hall, Matthew D; Logie, Natalie; Lucas, John T; MacEwan, Iain J; Olson, Adam C; Palmer, Joshua D; Patel, Samir; Pater, Luke E; Surgener, Stephanie; Tsang, Derek S; Vogel, Jennifer H; Wojcik, Alyssa; Wu, Cheng-Chia; Milgrom, Sarah A (2021. ) Improving the Pediatric Patient Experience During Radiation Therapy-A Children's Oncology Group Study.International journal of radiation oncology, biology, physics, , 109 (2 ) ,505-514 More Information

Hua, Chia-Ho; Vern-Gross, Tamara Z; Hess, Clayton B; Olch, Arthur J; Alaei, Parham; Sathiaseelan, Vythialingam; Deng, Jun; Ulin, Kenneth; Laurie, Fran; Gopalakrishnan, Mahesh; Esiashvili, Natia; Wolden, Suzanne L; Krasin, Matthew J; Merchant, Thomas E; Donaldson, Sarah S; FitzGerald, Thomas J; Constine, Louis S; Hodgson, David C; Haas-Kogan, Daphne A; Mahajan, Anita; Laack, Nadia N; Marcus, Karen J; Taylor, Paige A; Ahern, Verity A; Followill, David S; Buchsbaum, Jeffrey C; Breneman, John C; Kalapurakal, John A (2020. ) Practice patterns and recommendations for pediatric image-guided radiotherapy: A Children's Oncology Group report.Pediatric blood & cancer, , 67 (10 ) ,e28629 More Information

Rassiah, Prema; Esiashvili, Natia; Olch, Arthur J; Hua, Chia-Ho; Ulin, Ken; Molineu, Andrea; Marcus, Karen; Gopalakrishnan, Mahesh; Pillai, Susha; Kovalchuk, Nataliya; Liu, An; Niyazov, Greg; Peñagarícano, Jose; Cheung, Fred; Olson, Adam C; Wu, Cheng-Chia; Malhotra, Harish K; MacEwan, Iain J; Faught, Jacqueline; Breneman, John C; Followill, David S; FitzGerald, Thomas J; Kalapurakal, John A (2021. ) Practice Patterns of Pediatric Total Body Irradiation Techniques: A Children's Oncology Group Survey.International journal of radiation oncology, biology, physics, , 111 (5 ) ,1155-1164 More Information

Lazow, Margot A; Johnson, Sheryl L; Johnson, Neil D; Breneman, John C; Dexheimer, Phillip J; Szabo, Sara; Pressey, Joseph G (2020. ) Genome-Driven Therapy for Chemotherapy-Resistant Metastatic CDK6-Amplified Osteosarcoma.JCO precision oncology, , 4 ,498-504 More Information

Gutkin, Paulina M; Skinner, Lawrie; Jiang, Alice; Donaldson, Sarah S; Loo, Billy W; Oh, Justin; Wang, Yi Peng; von Eyben, Rie; Snyder, John; Bredfeldt, Jeremy S; Breneman, John C; Constine, Louis S; Faught, Austin M; Haas-Kogan, Daphne; Holmes, Jordan A; Krasin, Matthew; Larkin, Charlene; Marcus, Karen J; Maxim, Peter G; McClelland, Shearwood; Murphy, Blair; Palmer, Joshua D; Perkins, Stephanie M; Shen, Colette J; Terezakis, Stephanie; Bush, Karl; Hiniker, Susan M (2023. ) Feasibility of the Audio-Visual Assisted Therapeutic Ambience in Radiotherapy (AVATAR) System for Anesthesia Avoidance in Pediatric Patients: A Multicenter Trial.International journal of radiation oncology, biology, physics, , 117 (1 ) ,96-104 More Information

Mascia, Anthony E; Daugherty, Emily C; Breneman, John C (2023. ) FLASH Radiotherapy in a Value-Based Health Care Environment-Reply.JAMA oncology, , 9 (5 ) ,727 More Information

Mascia, Anthony E; Daugherty, Emily C; Zhang, Yongbin; Lee, Eunsin; Xiao, Zhiyan; Sertorio, Mathieu; Woo, Jennifer; Backus, Lori R; McDonald, Julie M; McCann, Claire; Russell, Kenneth; Levine, Lisa; Sharma, Ricky A; Khuntia, Dee; Bradley, Jeffrey D; Simone, Charles B; Perentesis, John P; Breneman, John C (2023. ) Proton FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases: The FAST-01 Nonrandomized Trial.JAMA oncology, , 9 (1 ) ,62-69 More Information

Poster Presentations

Guarnaschelli JN, Ying J, Warnick R, McPherson C, Imwalle L, Breneman JC (11-2010. ) Treatment for elderly glioblastoma patients: University of Cincinnati Experience .15th Annual Scientific Meeting of the Society for Neuro-Oncology, Montreal, Canada. . Conference. . Level:International

07-2011 -06-2012 Best Doctors in America Status:Recipient Level:National

Diagnosis,Cancer,Therapy,Cancer Therapy,Respiratory System

Academic - UC Health Barrett Cancer Center
Department of Radiation Oncology
Cincinnati  Ohio, 45267-0757
Phone: 513-584-5327
Fax: 513-584-4007
brenemjc@ucmail.uc.edu

UCH Proton Therapy Center
Liberty Township  Ohio, 45044
Phone: 513-584-BEAM
brenemjc@ucmail.uc.edu