Kelly Brunst

Kelly Jo Brunst

Asst Professor

Kettering Lab Complex

140

COM EH Epi Brunst Lab - 0056

160 Panzeca Way
Cincinnati, Ohio 45267

Professional Summary

Kelly J. Brunst, PhD is an Assistant Professor of Epidemiology in the Department of Environmental Health in the College of Medicine.  She earned her B.A. in Biology from Thomas More College (Crestview Hills, KY), her Ph.D. in Epidemiology from the University of Cincinnati (Cincinnati, OH), and completed a postdoctoral fellowship in the Department of Pediatrics at the Icahn School of Medicine at Mount Sinai (New York, NY). Her research focuses on understanding the programming mechanisms by which prenatal/early-life exposure to physical, social and/or nutritional factors influences childhood respiratory health, autonomic function, and neurodevelopment. She was recently awarded a National Institute of Environmental Health Sciences (NIEHS) Pathway to Independence Award to examine the effects of prenatal air pollution and maternal psychosocial stress exposure on childhood neurobehavioral outcomes. Her study utilizes novel mitochondrial DNA biomarkers of oxidative damage to address questions regarding the role of mitochondrial function in the programming of infant neurobehavior. Other research interests include epigenetics and metabolomics.

Education

PhD, University of Cincinnati 2012 (Epidemiology)

BA, Thomas More College 2007 (Biology)

Research Support

Grant: #R00ES024116 National Institute of Environmental Health Sciences Mitochondrial Markers of Pollution, Stress, and Neurobehavior Role:PI Active Type:Grant

Grant: #R00ES024116 Investigators:Brunst, Kelly 06-01-2017 -05-31-2020 National Institute of Environmental Health Sciences Mitochondrial Markers of Pollution, Stress, and Neurobehavior Role:PI $348,249.37 Active Level:Federal

Grant: #R03HD094236 Investigators:Brunst, Kelly; Martin, Vincent; Pinney, Susan; Ying, Jun 08-07-2018 -07-31-2020 National Institute of Child Health and Human Development Headaches and Migraines: Pubertal Parameter and Hormone Predictors in Adolescent Girls Role:Collaborator $86,674.00 Active Level:Federal

Grant: #HHSN302201800207P Investigators:Brunst, Kelly 09-01-2018 -08-31-2019 National Human Genome Research Institute Sequencing in the Classroom Curriculum PIlot Project Role:PI $10,000.00 Awarded Level:Federal

Grant: #17215 / R33ES024717 Investigators:Brunst, Kelly; Dietrich, Kim 12-02-2018 -07-31-2021 University of Illinois at Chicago Validation and Demonstration of Point-Of-Care Sensor for Multi Metal Exposure Assessment Role:PI $50,638.00 Awarded Level:Institution of Higher Education

Grant: #3200002784-20-084/ R01ES026446 Investigators:Brunst, Kelly 09-01-2019 -08-31-2020 National Institute of Environmental Health Sciences Developmental Effects of Manganese Exposure in Rural Adolescents: The CARES Cohort Comes of Age Role:PI $135,440.00 Awarded Level:Federal

Grant: #3210001358-20-109 / R01ES026446 Investigators:Brunst, Kelly 09-01-2019 -08-31-2020 National Institute of Environmental Health Sciences Developmental Effects of Manganese Exposure in Rural Adolescents: The CARES Cohort Comes of Age Role:PI $34,607.00 Awarded Level:Federal

Publications

Peer Reviewed Publications

Haynes, E. N.; Heckel, P.; Ryan, P.; Roda, S.; Leung, Y. K.; Sebastian, K.; Succop, P. (2010. )Environmental manganese exposure in residents living near a ferromanganese refinery in Southeast Ohio: a pilot study .Neurotoxicology, ,31 (5 ),468-74

Brunst, K. J.; Ryan, P. H.; Lockey, J. E.; Bernstein, D. I.; McKay, R. T.; Khurana Hershey, G. K.; Villareal, M.; Biagini Myers, J. M.; Levin, L.; Burkle, J.; Evans, S.; Lemasters, G. K. (2012. )Unraveling the relationship between aeroallergen sensitization, gender, second-hand smoke exposure, and impaired lung function .Pediatr Allergy Immunol, ,23 (5 ),479-87

Brunst, K. J.; Leung, Y. K.; Ryan, P. H.; Khurana Hershey, G. K.; Levin, L.; Ji, H.; Lemasters, G. K.; Ho, S. M. (2013. )Forkhead box protein 3 (FOXP3) hypermethylation is associated with diesel exhaust exposure and risk for childhood asthma .J Allergy Clin Immunol, ,131 (2 ),592-4 e1-3

Wright, R. J.; Brunst, K. J. (2013. )Programming of respiratory health in childhood: influence of outdoor air pollution .Curr Opin Pediatr, ,25 (2 ),232-9

Wright, R. J.; Brunst, K.J. (2013. )Social Determinants in Children's Environmental Health: The Stress-Health Paradigm .Textbook of Children’s Environmental Health, ,London ,Oxford University Press

Brunst, K. J.; Enlow, M. B.; Kannan, S.; Carroll, K. N.; Coull, B. A.; Wright, R. J. (2014. )Effects of Prenatal Social Stress and Maternal Dietary Fatty Acid Ratio on Infant Temperament: Does Race Matter? .Epidemiology (Sunnyvale), ,4 (4 ),976-91

Brunst, K. J.; Wright, R. O.; DiGioia, K.; Enlow, M. B.; Fernandez, H.; Wright, R. J.; Kannan, S. (2014. )Racial/ethnic and sociodemographic factors associated with micronutrient intakes and inadequacies among pregnant women in an urban US population .Public Health Nutr, ,17 (9 ),1960-70

Brunst, K. J.; Baccarelli, A. A.; Wright, R. J. (2015. )Integrating mitochondriomics in children's environmental health .J Appl Toxicol, ,35 (9 ),976-91

LeMasters, G.; Levin, L.; Bernstein, D. I.; Lockey, S. D. th; Lockey, J. E.; Burkle, J.; Khurana Hershey, G. K.; Brunst, K.; Ryan, P. H. (2015. )Secondhand smoke and traffic exhaust confer opposing risks for asthma in normal and overweight children .Obesity (Silver Spring), ,23 (1 ),32-6

Brunst, K. J.; Ryan, P. H.; Brokamp, C.; Bernstein, D.; Reponen, T.; Lockey, J.; Khurana Hershey, G. K.; Levin, L.; Grinshpun, S. A.; LeMasters, G. (2015. )Timing and Duration of Traffic-related Air Pollution Exposure and the Risk for Childhood Wheeze and Asthma .Am J Respir Crit Care Med, ,192 (4 ),421-7

Brunst, K.J.;Wright, R. J. (2016. )Social Disparities in Lung Growth and Respiratory Health .Health Disparities in Respiratory Medicine, ,New York, NY ,Springer Science+Business Media

Brunst, K. J.; Kannan, S.; Ni, Y. M.; Gennings, C.; Ganguri, H. B.; Wright, R. J. (2016. )Validation of a Food Frequency Questionnaire for Estimating Micronutrient Intakes in an Urban US Sample of Multi-Ethnic Pregnant Women .Matern Child Health J, ,20 (2 ),250-60

Lipton, L.; Brunst, K.J.; Kannan, S.; Ni, Y. M.; Ganguri, H. B.; Wright, R. J.; Bosquet Enlow, M. (2017. )Associations among prenatal stress, maternal antioxidant intakes in pregnancy, and child temperament at age 30 months .J Dev Orig Health Dis, ,

De Carli, M. M.; Baccarelli, A. A.; Trevisi, L.; Pantic, I.; Brennan, K. J.; Hacker, M. R.; Loudon, H.; Brunst, K. J.; Wright, R. O.; Wright, R. J.; Just, A. C. (2017. )Epigenome-wide cross-tissue predictive modeling and comparison of cord blood and placental methylation in a birth cohort .Epigenomics, ,9 (3 ),231-240

Brunst, K. J.; Rosa, M. J.; Jara, C.; Lipton, L. R.; Lee, A.; Coull, B. A.; Wright, R. J. (2017. )Impact of Maternal Lifetime Interpersonal Trauma on Children's Asthma: Mediation Through Maternal Active Asthma During Pregnancy .Psychosom Med, ,79 (1 ),91-100

Brunst, K.J.; Sanchez Guerra, M.; Gennings, C.; Hacker, M. R.; Jara, C.; Bosquet Enlow, M.; Wright, R.O.; Baccarelli, A.; Wright, R. J. (2017. )Maternal lifetime stress and prenatal psychological functioning are associated with decreased placental mitochondrial DNA copy number in the PRISM study .Am J Epidemiol, ,

Bosquet Enlow, M.; Devick, K.; Brunst, K.J.; Lipton, L.R.; Coull, B. A.; Wright, R. J. (2017. )Maternal Lifetime Trauma Exposure, Prenatal Cortisol, and Infant Negative Affectivity.Infancy, ,

Post Graduate Training and Education

09-01-2012-08-02-2016 Postdoctoral Fellow, Pediatric Environmental Health, Icahn School of Medicine at Mount Sinai, ,New York, New York

Contact Information

Academic - 160 Panzeca Way
Cincinnati  Ohio, 45267
Phone: 513-558-1723
kelly.brunst@uc.edu