Zhongyun Dong

Zhongyun Dong , MD, PhD

Professor

Vontz Center for Molecular Studies
3125 Eden Avenue, Room 1308
ML 0508
Cincinnati, Ohio 45267-0508
Phone 513-558-2176
Fax 513-558-6703
Email zhongyun.dong@uc.edu

Education

Medical Degree: Anhui Medical University 1983

Master's Degree: Peking Union Medical College 1986 (Immunology)

Doctoral Degree: Peking Union Medical College 1989 (Immunology)

Fellowship: The University of Texas MD Anderson Cancer Center 1991

Research and Practice Interests

Prostate Cancer, IFN-b Gene Therapy, Angiogenesis, PCNA inhibitor, Androgen receptor inhibitor, Androgen receptor

Positions and Work Experience

1986 -1989 Assistant Professor, Department of Immunology, Cancer Institute, Chinese Academy of Medical Sciences, Beijing, P.R. of China

1991 -1993 Research Associate, Department of Cell Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX

1994 -1997 Assistant Professor and Assistant Biologist, Department of Cell Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX

1997 -2003 Assistant Professor and Assistant Biologist (tenure-track), Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX

2003 -2004 Associate Professor and Associate Biologist, Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX

2004 -2011 Associate Professor, Department of Internal Medicine, Division of Hematology-Oncology, University of Cincinnati College of Medicine, Cincinnati, OH

2011 -To Present Professor, Department of Internal Medicine, Division of Hematology-Oncology, University of Cincinnati, Cincinnati, OH

Research Support

08-01-2012 -07-31-2014 NSF A pilot microfactory for Nonomedicine devices Role:Co-PI $817497 Active Type:Grant

03-01-2010 -02-28-2011 AREVA Med In vivo Evaluation of a single intravenous injection of AREVA agent in PC-3 orthotopic tumor model Role:PI

09-01-2008 -08-31-2013 NIH/NCI-R01 A novel androgen receptor antagonist Role:PI

Investigators:J Sankar, Z Dong 08-01-2008 -07-31-2013 NSF Revolutionizing Metallic Biomaterials Role:Co-I

2007 -2008 Interdisciplinary Faculty Research Support - UC Development of Luminescent Nanotubes for Cancer Diagnosis and Treatment Role:Co-PI

2006 -2007 UC Cancer Center Pilot Grant Development of Nanobiometric Sensor for detection of cytokines in cancers Role:PI

Grant: #RSG-98-332-04 Investigators:Dong, Zhongyun 07-01-2004 -06-30-2008 American Cancer Society - National Chapter A Novel Therapy for Locally Advanced Prostate Cancer Role:PI $720,000.00 Closed Level:Private Non-Profit

Grant: #R01 CA097099 Investigators:Dong, Zhongyun 08-20-2004 -03-31-2009 National Cancer Institute TGF-Beta 1-Regulated IL-8 Expression in Prostate Cancer Role:PI $1,122,863.00 Closed Level:Federal

Investigators:Dong, Zhongyun 04-01-2004 -12-31-2006 Department of Defense A Novel Therapy System for Occult Protstae Cancer Role:PI $559,223.00 Closed Level:Federal

Grant: #R01 CA131137 Investigators:Dong, Zhongyun; Khan, Sohaib; Lu, Shan; Wortman, Matthew 09-09-2008 -07-31-2014 National Cancer Institute A Novel Synthetic Androgen Receptor Antagonist Role:PI $1,599,078.00 Active Level:Federal

Grant: #260116B / EEC-0812348 Investigators:Behbehani, Michael; Butler, David; Dong, Zhongyun; Halsall, H Brian; Heineman, William; Montemagno, Carlo; Schulz, Mark; Shanov, Vesselin 09-01-2008 -08-31-2014 National Science Foundation Responsive Biosensors for Implants Role:Collaborator $3,800,000.00 Active Level:Federal

Grant: #SRS 006743 Investigators:Dong, Zhongyun; Rixe, Olivier 02-11-2010 -02-28-2012 AREVA Med, LLC. In Vivo Evaluation of a Single Intravenous Injection of AREVA Agent in PC-3 Orthotopic Tumor Model Role:Collaborator $180,000.00 Closed Level:Industry

Grant: #W81XWH-10-1-0367 Investigators:Choubey, Divaker; Dong, Zhongyun; Tarapore, Pheruza 05-15-2010 -05-14-2014 Department of the Army Medical Research and Materiel Command Targeted Delivery of Therapeutic RNA into Prostate Cancers Role:Collaborator $353,250.00 Active Level:Federal

Grant: #CBET-1239779 Investigators:Dong, Zhongyun; Mast, David; Meenakshi, Sundaram Murali; Schulz, Mark; Shanov, Vesselin 09-01-2012 -08-31-2014 National Science Foundation A Pilot Microfactory for Nanomedicine Devices Role:Collaborator $498,084.00 Active Level:Federal

Grant: #OBR Action Fund #994 Investigators:Dong, Zhongyun; Mast, David; Meenakshi, Sundaram Murali; Schulz, Mark; Shanov, Vesselin 07-01-2012 -06-30-2014 Ohio Board of Regents A Pilot Microfactory for Nanomedicine Devices Role:Collaborator $80,000.00 Active Level:State of Ohio

Grant: #W81XWH-10-1-0367 Investigators:Choubey, Divaker; Dong, Zhongyun; Tarapore, Pheruza 05-15-2010 -05-14-2014 Department of the Army Medical Research and Materiel Command Targeted Delivery of Therapeutic RNA into Prostate Cancers Role:Collaborator $353,250.00 Closed Level:Federal

Grant: #R21CA223049 Investigators:Dong, Zhongyun; Lu, Shan 08-01-2018 -07-31-2020 National Cancer Institute Preclinical safety and efficacy assessment of a novel PCNA inhibitor for prostate cancer therapy Role:PI $208,854.00 Active Level:Federal

Grant: #IIP-2016475 Investigators:Dong, Zhongyun; Heineman, William; Zhang, Peng 09-01-2020 -08-31-2022 National Science Foundation Development of visual hydrogen sensor for non-invasive monitoring of biodegradable metal implants Role:Collaborator $249,987.00 Awarded Level:Federal

Publications

Peer Reviewed Publications

Dong, Zhongyun; Meller, Jaroslaw; Succop, Paul; Wang, Jiang; Wikenheiser-Brokamp, Kathryn; Starnes, Sandra; Lu, Shan (2014. ) Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells.International journal of oncology, , 45 (3 ) ,978-84 More Information

Hong, Daeho; Saha, Partha; Chou, Da-Tren; Lee, Boeun; Collins, Boyce E; Tan, Zongqing; Dong, Zhongyun; Kumta, Prashant N (2013. ) In vitro degradation and cytotoxicity response of Mg-4% Zn-0.5% Zr (ZK40) alloy as a potential biodegradable material.Acta biomaterialia, , 9 (10 ) ,8534-47 More Information

Chou, Da-Tren; Hong, Daeho; Saha, Partha; Ferrero, Jordan; Lee, Boeun; Tan, Zongqing; Dong, Zhongyun; Kumta, Prashant N (2013. ) In vitro and in vivo corrosion, cytocompatibility and mechanical properties of biodegradable Mg-Y-Ca-Zr alloys as implant materials.Acta biomaterialia, , 9 (10 ) ,8518-33 More Information

Xue, D., Yun Y., Tan Z., Dong Z., and M. J. Schultz (2012. ) In Vivo and In Vitro degradation behavior of magnesium alloys as biomaterials .J. Mat. Sci. Tech., ,

Oleksowicz, L., Jiu, Y., Bracken, R.B, Gaitonde, K., Burke, B., Succop, P., Levin, L., Dong, Z., and Lu,S. (2012. ) Secretory Phospholipase A2-lla is a Target Gene of the HER/HER2-Elicited Pathway and Potential Plasma Biomarket for Poor Prognosis of Prostate Cancer .Prostate, , 72 ,1140-49

Yun, Y., Pixley, S., X. Cui, T., Dong, Z., Collins, B., Shanov, V., Ko, S., Pai1, D., Yarmolenko, S., Schulz, M. J., and J. Sankar (2012. ) Carbon Nanomaterials: From Therapeutics to Regenerative Medicine .Nanomedicine and Biotherapeutic Discovery, , 2 ,1000104

Tan, Z., Chen, P., Schneider, N., Glover, S., Cui, L., Torgue, J., Rixe, O., Spitz, H. B., an Dong, Z. (2012. ) Significant systemic therapeutic effects of high-LET immunoradiation by Pb-trastuzumab against prostatic tumors of androgen-independent human prostate cancer in mice .Int J. Oncol, , 40 ,1881-1888

Cui, L., Dillehay, K. L., Chen, W., Shen, D., Dong, Z., W. Li (2012. ) Association of the CYP1B1 Leu432Val polymorphism with the risk of prostate cancer: a meta-analysis .Mol Biol Reports, , 39 ,7465-71

Cui, L., Chen, P., Tan, Z., and Dong, Z. (2012. ) Hemostatic gelatin sponge is a superior matrix to Matrigel for estabishment of LNCaP human prostate cancer in nude mice .Prostate, , DOI:10 (1002/ ) ,pros. 22520

Tan, Z., Wortman, M., Dillehay, K.L., Seibel, W., Evelyn, C. R., Smith, S. J., Malkas, L., Zheng, Y., Lu, S., and Dong, Z. (2012. ) Small molecule targeting of PCNA chromatin association inhibits tumor cell growth .Mol Pharmacol, , 81 ,811-9

Cui, Lingling; Chen, Pingping; Tan, Zongqing; Li, Wenjie; Dong, Zhongyun (2012. ) Hemostatic gelatin sponge is a superior matrix to matrigel for establishment of LNCaP human prostate cancer in nude mice.The Prostate, , 72 (15 ) ,1669-77 More Information

Oleksowicz, Leslie; Liu, Yin; Bracken, R Bruce; Gaitonde, Krishnanath; Burke, Barbara; Succop, Paul; Levin, Linda; Dong, Zhongyun; Lu, Shan (2012. ) Secretory phospholipase A2-IIa is a target gene of the HER/HER2-elicited pathway and a potential plasma biomarker for poor prognosis of prostate cancer.The Prostate, , 72 (10 ) ,1140-9 More Information

Tan, Zongqing; Chen, Pingping; Schneider, Nathan; Glover, Samuel; Cui, Lingling; Torgue, Julien; Rixe, Olivier; Spitz, Henry B; Dong, Zhongyun (2012. ) Significant systemic therapeutic effects of high-LET immunoradiation by 212Pb-trastuzumab against prostatic tumors of androgen-independent human prostate cancer in mice.International journal of oncology, , 40 (6 ) ,1881-8 More Information

Tan, Zongqing; Wortman, Matthew; Dillehay, Kelsey L; Seibel, William L; Evelyn, Chris R; Smith, Shanna J; Malkas, Linda H; Zheng, Yi; Lu, Shan; Dong, Zhongyun (2012. ) Small-molecule targeting of proliferating cell nuclear antigen chromatin association inhibits tumor cell growth.Molecular pharmacology, , 81 (6 ) ,811-9 More Information

Kupert, Elena; Anderson, Marshall; Liu, Yin; Succop, Paul; Levin, Linda; Wang, Jiang; Wikenheiser-brokamp, Kathryn; Chen, Pingping; Pinney, Susan M; Macdonald, Trudy; Dong, Zhongyun; Starnes, Sandra; Lu, Shan (2011. ) Plasma secretory phospholipase A2-IIa as a potential biomarker for lung cancer in patients with solitary pulmonary nodules.BMC cancer, , 11 ,513 More Information

Kupert, E., Anderson, M. Liu, Y., Succop, P., Levin, L., Wang, J., Wikenheisser-Brokamp, K., Chen, P., Ponney, S., Macdonald, T., Dong, Z., Starnes, S. and Lu, S. (2011. ) Plasma secretory phospholipase A2-lla as a potential biomarker for lung cancer in patients with solitary pulmonary nodules .BMC Cancer, , 11 ,513

Dong, Zhongyun; Liu, Yin; Levin, Linda; Oleksowicz, Leslie; Wang, Jiang; Lu, Shan (2011. ) Vav3 oncogene is involved in regulation of secretory phospholipase A2-IIa expression in prostate cancer.Oncology reports, , 25 (6 ) ,1511-6 More Information

Meng, Qinghang; Peng, Zhimin; Chen, Liang; Si, Jutong; Dong, Zhongyun; Xia, Ying (2010. ) Nuclear Factor-?B modulates cellular glutathione and prevents oxidative stress in cancer cells.Cancer letters, , 299 (1 ) ,45-53 More Information

Lu, Shan; Tan, Zongqin; Wortman, Matthew; Lu, Shan; Dong, Zhongyun (2010. ) Preferential induction of G1 arrest in androgen-responsive human prostate cancer cells by androgen receptor signaling antagonists DL3 and antiandrogen bicalutamide.Cancer letters, , 298 (2 ) ,250-7 More Information

Dong, Zhongyun; Liu, Yin; Scott, Kieran F; Levin, Linda; Gaitonde, Krishnanath; Bracken, R Bruce; Burke, Barbara; Zhai, Qihui Jim; Wang, Jiang; Oleksowicz, Leslie; Lu, Shan (2010. ) Secretory phospholipase A2-IIa is involved in prostate cancer progression and may potentially serve as a biomarker for prostate cancer.Carcinogenesis, , 31 (11 ) ,1948-55 More Information

Cho, Hoon-Sung; Dong, Zhongyun; Pauletti, Giovanni M; Zhang, Jiaming; Xu, Hong; Gu, Hongchen; Wang, Lumin; Ewing, Rodney C; Huth, Christopher; Wang, Feng; Shi, Donglu (2010. ) Fluorescent, superparamagnetic nanospheres for drug storage, targeting, and imaging: a multifunctional nanocarrier system for cancer diagnosis and treatment.ACS nano, , 4 (9 ) ,5398-404 More Information

Yun, YeoHeung; Dong, Zhongyun; Tan, Zongqing; Schulz, Mark J (2010. ) Development of an electrode cell impedance method to measure osteoblast cell activity in magnesium-conditioned media.Analytical and bioanalytical chemistry, , 396 (8 ) ,3009-15 More Information

Liu, Yin; Wu, Xiaoyang; Dong, Zhongyun; Lu, Shan (2010. ) The molecular mechanism of Vav3 oncogene on upregulation of androgen receptor activity in prostate cancer cells. International journal of oncology, , 36 (3 ) ,623-33

Lu, Shan; Tan, Zongqin; Wortman, Matt; Lu, Shan; Dong, Zhongyun (2010. ) Regulation of heat shock protein 70-1 expression by androgen receptor and its signaling in human prostate cancer cells. International journal of oncology, , 36 (2 ) ,459-67

Yun, Yeo-Heung; Eteshola, Edward; Bhattacharya, Amit; Dong, Zhongyun; Shim, Joon-Sub; Conforti, Laura; Kim, Dogyoon; Schulz, Mark J; Ahn, Chong H; Watts, Nelson (2009. ) Tiny medicine: nanomaterial-based biosensors.Sensors (Basel, Switzerland), , 9 (11 ) ,9275-99 More Information

Guo, Yan; Shi, Donglu; Lian, Jie; Dong, Zhongyun; Wang, Wei; Cho, Hoonsung; Liu, Guokui; Wang, Lumin; Ewing, Rodney C (2008. ) Quantum dot conjugated hydroxylapatite nanoparticles for in vivo imaging.Nanotechnology, , 19 (17 ) ,175102 More Information

Liu, Yin; Mo, Jun Qin; Hu, Qiande; Boivin, Gregory; Levin, Linda; Lu, Shan; Yang, Dianer; Dong, Zhongyun; Lu, Shan (2008. ) Targeted overexpression of vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer.Cancer research, , 68 (15 ) ,6396-406 More Information

Lee, Kiwon; Liu, Yin; Mo, Jun Qin; Zhang, Jinsong; Dong, Zhongyun; Lu, Shan (2008. ) Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer.BMC cancer, , 8 ,158 More Information

Wang, Daren; Lu, Shan; Dong, Zhongyun (2007. ) Regulation of TGF-beta1 gene transcription in human prostate cancer cells by nitric oxide.The Prostate, , 67 (16 ) ,1825-33 More Information

Yun, Yeoheung; Dong, Zhongyun; Shanov, Vesselin N; Schulz, Mark J (2007. ) Electrochemical impedance measurement of prostate cancer cells using carbon nanotube array electrodes in a microfluidic channel.Nanotechnology, , 18 (46 ) ,465505 More Information

Lu, Shan; Lee, Juwon; Revelo, Monica; Wang, Xiaohong; Lu, Shan; Dong, Zhongyun (2007. ) Smad3 is overexpressed in advanced human prostate cancer and necessary for progressive growth of prostate cancer cells in nude mice.Clinical cancer research : an official journal of the American Association for Cancer Research, , 13 (19 ) ,5692-702 More Information

Yun, YeoHeung; Bange, Adam; Shanov, Vesselin N; Heineman, William R; Halsall, H Brian; Dong, Zhongyun; Jazieh, Abdul; Tu, Yi; Wong, Danny; Pixley, Sarah; Behbehani, Michael; Schulz, Mark J (2007. ) A carbon nanotube needle biosensor. Journal of nanoscience and nanotechnology, , 7 (7 ) ,2293-300

Lu, Shan; Wang, Amy; Lu, Shan; Dong, Zhongyun (2007. ) A novel synthetic compound that interrupts androgen receptor signaling in human prostate cancer cells.Molecular cancer therapeutics, , 6 (7 ) ,2057-64 More Information

Yun, Yeoheung; Gollapudi, Ram; Shanov, Vesselin; Schulz, Mark J; Dong, Zhongyun; Jazieh, Abdul; Heineman, William R; Halsall, H Brian; Wong, Danny K Y; Bange, Adam; Tu, Yi; Subramaniam, Srinivas (2007. ) Carbon nanotubes grown on stainless steel to form plate and probe electrodes for chemical/biological sensing. Journal of nanoscience and nanotechnology, , 7 (3 ) ,891-7

Lee, Juwon; Wang, Amy; Hu, Qiande; Lu, Shan; Dong, Zhongyun (2006. ) Adenovirus-mediated interferon-beta gene transfer inhibits angiogenesis in and progression of orthotopic tumors of human prostate cancer cells in nude mice. International journal of oncology, , 29 (6 ) ,1405-12

Dong, Zhongyun; Liu, Yin; Lu, Shan; Wang, Amy; Lee, Kiwon; Wang, Lu-Hai; Revelo, Monica; Lu, Shan (2006. ) Vav3 oncogene is overexpressed and regulates cell growth and androgen receptor activity in human prostate cancer.Molecular endocrinology (Baltimore, Md.), , 20 (10 ) ,2315-25 More Information

Lu, Shan; Dong, Zhongyun (2006. ) Characterization of TGF-beta-regulated interleukin-8 expression in human prostate cancer cells.The Prostate, , 66 (9 ) ,996-1004 More Information

Zhang, Fahao; Lee, Juwon; Wang, Daren; Dong, Zhongyun (2006. ) Differential growth of IFN-beta-engineered tumor cells in nude and IFN receptor-null mice.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, , 26 (2 ) ,108-18 More Information

Liu, Guozhen; Zhang, Fahao; Lee, Juwon; Dong, Zhongyun (2005. ) Selective induction of interleukin-8 expression in metastatic melanoma cells by transforming growth factor-beta 1.Cytokine, , 31 (3 ) ,241-9 More Information

Zhang, Fahao; Lee, Juwon; Lu, Shan; Pettaway, Curtis A; Dong, Zhongyun (2005. ) Blockade of transforming growth factor-beta signaling suppresses progression of androgen-independent human prostate cancer in nude mice.Clinical cancer research : an official journal of the American Association for Cancer Research, , 11 (12 ) ,4512-20 More Information

Uehara, Hisanori; Troncoso, Patricia; Johnston, Dennis; Bucana, Corazon D; Dinney, Colin; Dong, Zhongyun; Fidler, Isaiah J; Pettaway, Curtis A (2005. ) Expression of interleukin-8 gene in radical prostatectomy specimens is associated with advanced pathologic stage.The Prostate, , 64 (1 ) ,40-9 More Information

Ozawa, Shutaro; Lu, Weixin; Bucana, Corazon D; Kanayama, Hiro-Omi; Shinohara, Hisashi; Fidler, Isaiah J; Dong, Zhongyun (2003. ) Regression of primary murine colon cancer and occult liver metastasis by intralesional injection of lyophilized preparation of insect cells producing murine interferon-beta. International journal of oncology, , 22 (5 ) ,977-84

Lu, Weixin; Su, Jindong; Kim, Lee Su; Bucana, Corazon D; Donawho, Cherrie; He, Junqing; Fidler, Isaiah J; Dong, Zhongyun (2003. ) Active specific immunotherapy against occult brain metastasis. Cancer research, , 63 (6 ) ,1345-50

Harmey, Judith H; Bucana, Corazon D; Lu, Weixin; Byrne, Anne Marie; McDonnell, Susan; Lynch, Conor; Bouchier-Hayes, David; Dong, Zhongyun (2002. ) Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion.International journal of cancer. Journal international du cancer, , 101 (5 ) ,415-22 More Information

Zhang, Fahao; Lu, Weixin; Dong, Zhongyun (2002. ) Tumor-infiltrating macrophages are involved in suppressing growth and metastasis of human prostate cancer cells by INF-beta gene therapy in nude mice. Clinical cancer research : an official journal of the American Association for Cancer Research, , 8 (9 ) ,2942-51

Lu, Weixin; Dong, Zhongyun; Donawho, Cherrie; Fidler, Isaiah J (2002. ) Specific immunotherapy against occult cancer metastases.International journal of cancer. Journal international du cancer, , 100 (4 ) ,480-5 More Information

Takeuchi, Osamu; Sato, Shintaro; Horiuchi, Takao; Hoshino, Katsuaki; Takeda, Kiyoshi; Dong, Zhongyun; Modlin, Robert L; Akira, Shizuo (2002. ) Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. Journal of immunology (Baltimore, Md. : 1950), , 169 (1 ) ,10-4

Makar, Tapas Kumar; Wilt, Susan; Dong, Zhongyun; Fishman, Paul; Mouradian, M Maral; Dhib-Jalbut, Suhayl (2002. ) IFN-beta gene transfer into the central nervous system using bone marrow cells as a delivery system.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, , 22 (7 ) ,783-91 More Information

Davies, Michael A; Kim, Sun J; Parikh, Nila U; Dong, Zhongyun; Bucana, Corazon D; Gallick, Gary E (2002. ) Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research, , 8 (6 ) ,1904-14

Izawa, Jonathan I; Sweeney, Paul; Perrotte, Paul; Kedar, Daniel; Dong, Zhongyun; Slaton, Joel W; Karashima, Takashi; Inoue, Keji; Benedict, William F; Dinney, Colin P N (2002. ) Inhibition of tumorigenicity and metastasis of human bladder cancer growing in athymic mice by interferon-beta gene therapy results partially from various antiangiogenic effects including endothelial cell apoptosis. Clinical cancer research : an official journal of the American Association for Cancer Research, , 8 (4 ) ,1258-70

Zhao D.;Wu J.;Chou D.T.;Hoagland W.;Benson D.;Dong Z.;Kumta P.N.;Heineman W.R. (01-01-2020. ) Visual Hydrogen Mapping Sensor for Noninvasive Monitoring of Bioresorbable Magnesium Implants In Viv.JOM, , More Information

Lu S.;Dong Z. (01-01-2019. ) Additive effects of a small molecular PCNA inhibitor PCNA-I1S and DNA damaging agents on growth inhi.PLoS ONE, , 14 (10 ) , More Information

Yin Z.;Dong Z.;Cahay M.;Pixley S.;Haworth K.J.;Rahimi M.;Goh S.K.;Starnes S.;Patwardhan M.;Chaudhary S.;Schulz M.J. (01-01-2019. ) Carbon nanotube wire for use in precision medical devices.Nanotube Superfiber Materials: Science, Manufacturing, Commercialization, , 825-849 More Information

Wu J.;Zhao D.;Ohodnicki J.M.;Lee B.;Roy A.;Yao R.;Chen S.;Dong Z.;Heineman W.R.;Kumta P.N. (03-12-2018. ) In Vitro and in Vivo Evaluation of Multiphase Ultrahigh Ductility Mg-Li-Zn Alloys for Cardiovascular.ACS Biomaterials Science and Engineering, , 4 (3 ) ,919-932 More Information

Koo Y.;Lee H.;Dong Z.;Kotoka R.;Sankar J.;Huang N.;Yun Y. (12-01-2017. ) The Effects of Static and Dynamic Loading on Biodegradable Magnesium Pins in Vitro and in Vivo.Scientific Reports, , 7 (1 ) , More Information

Zhao D.;Wang T.;Nahan K.;Guo X.;Zhang Z.;Dong Z.;Chen S.;Chou D.;Hong D.;Kumta P.;Heineman W. (03-01-2017. ) In vivo characterization of magnesium alloy biodegradation using electrochemical H2.Acta Biomaterialia, , 50 ,556-565 More Information

Zhao D.;Wang T.;Hoagland W.;Benson D.;Dong Z.;Chen S.;Chou D.;Hong D.;Wu J.;Kumta P.;Heineman W. (11-01-2016. ) Visual H2 sensor for monitoring biodegradation of magnesium implants in vivo.Acta Biomaterialia, , 45 ,399-409 More Information

Zhao D.;Wang T.;Kuhlmann J.;Dong Z.;Chen S.;Joshi M.;Salunke P.;Shanov V.;Hong D.;Kumta P.;Heineman W. (05-01-2016. ) In vivo monitoring the biodegradation of magnesium alloys with an electrochemical H2.Acta Biomaterialia, , 36 ,361-368 More Information

Zhao D.;Wang T.;Guo X.;Kuhlmann J.;Doepke A.;Dong Z.;Shanov V.;Heineman W. (04-01-2016. ) Monitoring Biodegradation of Magnesium Implants with Sensors.JOM, , 68 (4 ) ,1204-1208 More Information

Joshi M.;Salunke P.;Zhang G.;Chaswal V.;Dong Z.;Shanov V. (09-04-2015. ) Magnesium Single Crystal as a Biodegradable Implant Material.Biomaterials Science: Processing, Properties and Applications V: Ceramic Transactions, Volume 254, , 97-113 More Information

Dillehay K.;Seibel W.;Zhao D.;Lu S.;Dong Z. (03-01-2015. ) Target validation and structure-activity analysis of a series of novel PCNA inhibitors.Pharmacology Research and Perspectives, , 3 (2 ) , More Information

Jang Y.;Tan Z.;Jurey C.;Xu Z.;Dong Z.;Collins B.;Yun Y.;Sankar J. (03-01-2015. ) Understanding corrosion behavior of Mg-Zn-Ca alloys from subcutaneous mouse model: Effect of Zn elem.Materials Science and Engineering C, , 48 ,28-40 More Information

Smith S.J.;Gu L.;Phipps E.A.;Dobrolecki L.E.;Mabrey K.S.;Gulley P.;Dillehay K.L.;Dong Z.;Fields G.B.;Chen Y.R.;Ann D.;Hickey R.J.;Malkas L.H. (02-01-2015. ) A peptide mimicking a region in proliferating cell nuclear antigen specific to key protein interacti.Molecular Pharmacology, , 87 (2 ) ,263-276 More Information

Joshi M.;Salunke P.;Zhang G.;Chaswal V.;Dong Z.;Shanov V. (01-01-2015. ) Magnesium single crystal as a biodegradable implant material .Ceramic Transactions, , 254 ,97-113

Dillehay K.;Lu S.;Dong Z. (12-01-2014. ) Antitumor effects of a novel small molecule targeting PCNA chromatin association in prostate cancer.Molecular Cancer Therapeutics, , 13 (12 ) ,2817-2826 More Information

Jang Y.;Tan Z.;Jurey C.;Collins B.;Badve A.;Dong Z.;Park C.;Kim C.S.;Sankar J.;Yun Y. (12-01-2014. ) Systematic understanding of corrosion behavior of plasma electrolytic oxidation treated AZ31 magnesi.Materials Science and Engineering C, , 45 ,45-55 More Information

Yun Y.;Jang Y.;Wang J.;Dong Z.;Shanov V.;Sankar J.;Koo Y.;White L.;Collins B. (01-01-2014. ) Biodegradable magnesium implant: In vivo and in vitro convergence.ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE), , 14 , More Information

Schneider N.;Lobaugh M.;Tan Z.;Sandwall P.;Chen P.;Glover S.;Cui L.;Murry M.;Dong Z.;Torgue J.;Spitz H. (04-01-2013. ) Biodistribution of 212Pb conjugated trastuzumab in mice.Journal of Radioanalytical and Nuclear Chemistry, , 296 (1 ) ,75-81 More Information

Cui L.;Dillehay K.;Chen W.;Shen D.;Dong Z.;Li W. (07-01-2012. ) Association of the CYP1B1 Leu432Val polymorphism with the risk of prostate cancer: A meta-analysis.Molecular Biology Reports, , 39 (7 ) ,7465-7471 More Information

Xue D.;Tan Z.;Schulz M.;Vanooij W.;Sankar J.;Yun Y.;Dong Z. (07-01-2012. ) Corrosion studies of modified organosilane coated magnesium-yttrium alloy in different environments.Materials Science and Engineering C, , 32 (5 ) ,1230-1236 More Information

Xue D.;Yun Y.;Tan Z.;Dong Z.;Schulz M. (03-01-2012. ) In Vivo and In Vitro Degradation Behavior of Magnesium Alloys as Biomaterials.Journal of Materials Science and Technology, , 28 (3 ) ,261-267 More Information

Schulz M.;Doepke A.;Guo X.;Kuhlmann J.;Halsall B.;Heineman W.;Dong Z.;Tan Z.;Xue D.;Lee N.;Yun Y.;Liu Y.;Hurd D.;Shanov V.;Rai D.;Witte F.;Kumar D.;Yarmolenko S.;Pixley S.;Hopkins T.;Jayasinghe C.;Sundaramurthy S. (01-01-2010. ) Responsive biosensors for biodegradable magnesium implants.ASME International Mechanical Engineering Congress and Exposition, Proceedings, , 14 ,109-116 More Information

Shi D.;Cho H.;Huth C.;Wang F.;Dong Z.;Pauletti G.;Lian J.;Wang W.;Liu G.;Bud'Ko S.;Wang L.;Ewing R. (12-18-2009. ) Conjugation of quantum dots and Fe3 O4 on carbon nanot.Applied Physics Letters, , 95 (22 ) , More Information

Yun Y.H.;Shanov V.N.;Bange A.;Heineman W.R.;Halsall H.B.;Seth G.;Pixley S.K.;Behbehani M.;Bhattacharya A.;Dong Z.;Yarmolenko S.;Kang I.;Schulz M.J. (12-01-2009. ) Carbon nanotube smart materials for biology and medicine.NanoScience in Biomedicine, , 451-484 More Information

Yun Y.;Eteshola E.;Bhattacharya A.;Dong Z.;Shim J.;Conforti L.;Kim D.;Schulz M.;Ahn C.;Watts N. (11-01-2009. ) Tiny medicine: Nanomaterial-based biosensors.Sensors, , 9 (11 ) ,9275-9299 More Information

Yun Y.;Dong Z.;Yang D.;Shanov V.;Yarmolenko S.;Xu Z.;Kumta P.;Sfeir C.;Doepke A.;Schulz M. (09-17-2009. ) Biodegradable Mg for bone implants: Corrosion and osteoblast culture studies.ASME International Mechanical Engineering Congress and Exposition, Proceedings, , 15 ,125-129 More Information

Yun Y.;Dong Z.;Yang D.;Schulz M.;Shanov V.;Yarmolenko S.;Xu Z.;Kumta P.;Sfeir C. (08-01-2009. ) Biodegradable Mg corrosion and osteoblast cell culture studies.Materials Science and Engineering C, , 29 (6 ) ,1814-1821 More Information

Shi D.;Cho H.S.;Chen Y.;Xu H.;Gu H.;Lian J.;Wang W.;Liu G.;Huth C.;Wang L.;Ewing R.C.;Budko S.;Pauletti G.M.;Dong Z. (06-05-2009. ) Fluorescent polystyrene-Fe3O4 composite nanospheres fo.Advanced Materials, , 21 (21 ) ,2170-2173 More Information

Yun Y.H.;Dong Z.;Tan Z.;Schulz M.J.;Shanov V. (04-30-2009. ) Fibroblast cell behavior on chemically functionalized carbon nanomaterials.Materials Science and Engineering C, , 29 (3 ) ,719-725 More Information

Yun Y.;Dong Z.;Lee N.;Liu Y.;Xue D.;Guo X.;Kuhlmann J.;Doepke A.;Halsall H.;Heineman W.;Sundaramurthy S.;Schulz M.;Yin Z.;Shanov V.;Hurd D.;Nagy P.;Li W.;Fox C. (01-01-2009. ) Revolutionizing biodegradable metals.Materials Today, , 12 (10 ) ,22-32 More Information

Guo Y.;Shi D.;Cho H.;Dong Z.;Kulkarni A.;Pauletti G.;Wang W.;Lian J.;Liu W.;Ren L.;Zhang Q.;Liu G.;Huth C.;Wang L.;Ewing R. (09-10-2008. ) In vivo imaging and drug storage by quantum-dot-conjugated carbon nanotubes.Advanced Functional Materials, , 18 (17 ) ,2489-2497 More Information

Yun Y.;Dong Z.;Shanov V.;Doepke A.;Heineman W.;Halsall H.;Bhattacharya A.;Wong D.;Schulz M. (07-28-2008. ) Fabrication and characterization of carbon nanotube array electrodes with gold nanoparticle tips.Sensors and Actuators, B: Chemical, , 133 (1 ) ,208-212 More Information

Guo Y.;Shi D.;Lian J.;Dong Z.;Wang W.;Cho H.;Liu G.;Wang L.;Ewing R. (04-30-2008. ) Quantum dot conjugated hydroxylapatite nanoparticles for in vivo imaging.Nanotechnology, , 19 (17 ) , More Information

Shi D.;Guo Y.;Dong Z.;Lian J.;Wang W.;Liu G.;Wang L.;Ewing R. (04-21-2008. ) Quantum-dot-activated luminescent carbon nanotubes via a nano scale surface functionalization for in.Advanced Materials, , 20 (8 ) ,1 More Information

Yun Y.H.;Dong Z.;Shanov V.;Heineman W.R.;Halsall H.B.;Bhattacharya A.;Conforti L.;Narayan R.K.;Ball W.S.;Schulz M.J. (12-01-2007. ) Nanotube electrodes and biosensors.Nano Today, , 2 (6 ) ,30-37 More Information

Yun Y.;Dong Z.;Shanov V.;Schulz M. (11-21-2007. ) Electrochemical impedance measurement of prostate cancer cells using carbon nanotube array electrode.Nanotechnology, , 18 (46 ) , More Information

Shi D.;Guo Y.;Dong Z.;Lian J.;Wang W.;Liu G.;Wang L.;Ewing R. (11-19-2007. ) Quantum-dot-activated luminescent carbon nanotubes via a nano scale surface functionalization for in.Advanced Materials, , 19 (22 ) ,4033-4037 More Information

Yun Y.;Dong Z.;Shanov V.;Bange A.;Heineman W.;Halsall H.;Conforti L.;Bhattacharya A.;Schulz M. (11-01-2007. ) On-line carbon nanotube-based biosensors in microfluidic channels.Proceedings of SPIE - The International Society for Optical Engineering, , 6528 , More Information

Guo Y.;Wang W.;Cho H.S.;Lian J.;Ewing R.;Wang L.;Liu G.K.;Dong Z.Y.;Shi D. (08-23-2007. ) Luminescent carbon nanotubes for biomedical diagnosis and treatment .2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings, , 2 ,251-254

Yun Y.H.;Bange A.;Heineman W.R.;Halsall H.B.;Shanov V.N.;Dong Z.;Pixley S.;Behbehani M.;Jazieh A.;Tu Y.;Wong D.K.Y.;Bhattacharya A.;Schulz M.J. (04-10-2007. ) A nanotube array immunosensor for direct electrochemical detection of antigen-antibody binding.Sensors and Actuators, B: Chemical, , 123 (1 ) ,177-182 More Information

Yun Y.H.;Shanov V.;Schulz M.J.;Dong Z.;Jazieh A.;Heineman W.R.;Halsall H.B.;Wong D.K.Y.;Bange A.;Tu Y.;Subramaniam S. (12-14-2006. ) High sensitivity carbon nanotube tower electrodes.Sensors and Actuators, B: Chemical, , 120 (1 ) ,298-304 More Information

Yun Y.H.;Bange A.;Shanov V.N.;Heineman W.R.;Brian Halsall H.;Dong Z.;Jazieh A.;Tu Y.;Wong D.;Pixley S.;Behbehani M.;Schulz M.J. (12-01-2006. ) Fabrication and characterization of a multiwall carbon nanotube needle biosensor .2006 6th IEEE Conference on Nanotechnology, IEEE-NANO 2006, , 1 ,280-283

Shi D.;Guo Y.;Wang W.;Cho H.;Lian J.;Wang L.;Ewing R.G.;Liu G.;Dong Z. (11-28-2006. ) Deposition of rare-earth doped nanophosphors on multi-wall carbon nanotube surfaces - a new approach .Proceedings of the International Conference on Manufacturing Science and Engineering, , 2006 ,

Yun Y.;Bange A.;Shanov V.;Heineman W.;Brian Halsall H.;Pixley S.;Behbehani M.;Dong Z.;Tu Y.;Yarmolenko S.;Neralla S.;Schulz M. (07-20-2006. ) Carbon nanotube array smart materials.Proceedings of SPIE - The International Society for Optical Engineering, , 6172 , More Information

Olson M.;Lee J.;Zhang F.;Wang A.;Dong Z. (07-17-2006. ) Inducible nitric oxide synthase activity is essential for inhibition of prostatic tumor growth by in.Cancer Gene Therapy, , 13 (7 ) ,676-685 More Information

Yun Y.;Schulz M.;Bange A.;Heineman W.;Halsall H.;Shanov V.;Behbehani M.;Pixley S.;Bhattacharya A.;Dong Z.;Wong D. (06-01-2006. ) A nanotube composite microelectrode for monitoring dopamine levels using cyclic voltammetry and diff.Proceedings of the Institution of Mechanical Engineers, Part N: Journal of Nanoengineering and Nanosystems, , 220 (2 ) ,53-60 More Information

Shi D.;Lian J.;Wang W.;Liu G.;He P.;Dong Z.;Wang L.;Ewing R. (01-19-2006. ) Luminescent carbon nanotubes by surface functionalization.Advanced Materials, , 18 (2 ) ,189-193 More Information

Lu W.;Dong Z.;Donawho C.;Fidler I. (08-01-2002. ) ICAM-1 expression and the soluble ICAM-1 level for evaluating the metastatic potential of gastric ca.International Journal of Cancer, , 100 (4 ) ,486-490 More Information

Cao G.;Su J.;Lu W.;Zhang F.;Zhao G.;Marteralli D.;Dong Z. (01-01-2002. ) Multiple arteriovenous malformations with hemorrhage.Acta Neurochirurgica, , 144 (1 ) ,97-101 More Information

Zhang F.;Zhao G.;Dong Z. (07-07-2001. ) Phosphatidylcholine-specific phospholipase C regulates activation of RAW264.7 macrophage-like cells .Journal of Leukocyte Biology, , 69 (6 ) ,1060-1066

Zhang F.;Zhao G.;Dong Z. (06-21-2001. ) Phosphatidylcholine-specific phospholipase C and D in stimulation of RAW264.7 mouse macrophage-like .International Immunopharmacology, , 1 (7 ) ,1375-1384 More Information

Cao G.;Su J.;Lu W.;Zhang F.;Zhao G.;Marteralli D.;Dong Z. (01-01-2001. ) Adenovirus-mediated interferon-? gene therapy suppresses growth and metastasis of human prostate can.Cancer Gene Therapy, , 8 (7 ) ,497-505 More Information

Fidler I.J.;Singh R.K.;Yoneda J.;Kumar R.;Xu L.;Dong Z.;Bielenberg D.R.;McCarty M.;Ellis L.M. (05-01-2000. ) Critical determinants of neoplastic angiogenesis .Cancer Journal, , 6 (SUPPL. 3 ) ,

Kumar R.;Xie K.;Eue I.;Dong Z.;Killion J.;Fidler I. (01-01-2000. ) Differential regulation of type IV collagenases and metalloelastase in murine macrophages by the syn.International Journal of Immunopharmacology, , 22 (6 ) ,431-443 More Information

Bruns C.;Shinohara H.;Harbison M.;Davis D.;Nelkin G.;Killion J.;McConkey D.;Dong Z.;Fidler I. (01-01-2000. ) Therapy of human pancreatic carcinoma implants by irinotecan and the oral immunomodulator JBT 3002 i .Cancer Research, , 60 (1 ) ,2-7

Lu W.;Fidler I.;Dong Z. (10-15-1999. ) Eradication of primary murine fibrosarcomas and induction of systemic immunity by adenovirus mediate .Cancer Research, , 59 (20 ) ,5202-5208

Dong Z.;Greene G.;Pettaway C.;Dinney C.;Eue I.;Lu W.;Bucana C.;Balbay M.;Bielenberg D.;Fidler I. (02-15-1999. ) Suppression of angiogenesis, tumorigenicity, and metastasis by human prostate cancer cells engineere .Cancer Research, , 59 (4 ) ,872-879

Kumar R.;Yoneda J.;Fidler I.J.;Dong Z. (01-01-1999. ) GM-CSF-transduced B16 melanoma cells are highly susceptible to lysis by normal murine macrophages an.Journal of Leukocyte Biology, , 65 (1 ) ,102-108 More Information

Dong Z.;Yoneda J.;Kumar R.;Fidler I.J. (08-17-1998. ) Angiostatin-mediated suppression of cancer metastases by primary neoplasms engineered to produce gra.Journal of Experimental Medicine, , 188 (4 ) ,755-763 More Information

Eue I.;Kumar R.;Dong Z.;Killion J.;Fidler I. (01-01-1998. ) Induction of nitric oxide production and tumoricidal properties in murine macrophages by a new synth.Journal of Immunotherapy, , 21 (5 ) ,340-351 More Information

Dong Z.;Killion J.;Kumar R.;Eue I.;Yang X.;Lu W.;Su B.;Fidler I. (01-01-1998. ) Activation of cytokine production, tumoricidal properties, and tyrosine phosphorylation of MAPKs in .Journal of Leukocyte Biology, , 63 (6 ) ,766-774 More Information

Dong Z.;Juang S.;Kumar R.;Eue I.;Xie K.;Bielenberg D.;Lu W.;Bucana C.;Yang X.;Fidler I. (01-01-1998. ) Suppression of tumorigenicity and metastasis in murine UV-2237 fibrosarcoma cells by infection with .Cancer Immunology Immunotherapy, , 46 (3 ) ,137-146 More Information

Xie K.;Bielenberg D.;Huang S.;Xu L.;Salas T.;Juang S.;Dong Z.;Fidler I. (12-01-1997. ) Abrogation of tumorigenicity and metastasis of murine and human tumor cells by transfection with the .Clinical Cancer Research, , 3 (12 I ) ,2283-2294

Dong Z.;Kumar R.;Yang X.;Fidler I. (03-21-1997. ) Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung ca.Cell, , 88 (6 ) ,801-810 More Information

Xie K.;Huang S.;Dong Z.;Juang S.;Wang Y.;Fidler I. (03-19-1997. ) Destruction of bystander cells by tumor cells transfected with inducible nitric oxide (NO) synthase .Journal of the National Cancer Institute, , 89 (6 ) ,421-427 More Information

Dong Z.;Yang X.;Fidler I. (01-01-1997. ) Neutralization of endogenous interferon-? increases the efficiency of adenoviral vector-mediated gen.Journal of Interferon and Cytokine Research, , 17 (7 ) ,401-407 More Information

Kumar R.;Eue I.;Dong Z.;Killion J.;Fidler I. (01-01-1997. ) Expression of inflammatory cytokines by murine macrophages activated with a new synthetic lipopeptid.Cancer Biotherapy and Radiopharmaceuticals, , 12 (5 ) ,333-340 More Information

Wei Q.;Cheng L.;Xie K.;Bucana C.;Dong Z. (01-01-1997. ) Direct correlation between DNA repair capacity and metastatic potential of K-1735 murine melanoma ce.Journal of Investigative Dermatology, , 108 (1 ) ,3-6 More Information

Dinney C.;Parker C.;Dong Z.;Fan D.;Eve B.;Bucana C.;Radinsky R. (01-01-1997. ) Therapy of human transitioneal cell carcinoma of the bladder by oral administration of the epidermal .Clinical Cancer Research, , 3 (2 ) ,161-168

Kumar R.;Dong Z.;Fidler I. (12-01-1996. ) Differential Regulation of Metalloelastase Activity in Murine Peritoneal Macrophages by Granulocyte- .Journal of Immunology, , 157 (11 ) ,5104-5111

Xie K.;Huang S.;Wang Y.;Beltran P.;Juang S.;Dong Z.;Reed J.;McDonnell T.;McConkey D.;Fidler I. (11-27-1996. ) Bcl-2 protects cells from cytokine-induced nitric-oxide-dependent apoptosis.Cancer Immunology Immunotherapy, , 43 (2 ) ,109-115 More Information

Xie K.;Dong Z.;Fidler I. (01-01-1996. ) Activation of nitric oxide synthase gene for inhibition of cancer metastasis.Journal of Leukocyte Biology, , 59 (6 ) ,797-803 More Information

Killion J.;Bucana C.;Radinsky R.;Dong Z.;O'Reilly T.;Bilbe G.;Tarcsay L.;Fidler I. (01-01-1996. ) Maintenance of intestinal epithelium structural integrity and mucosal leukocytes during chemotherapy.Cancer Biotherapy and Radiopharmaceuticals, , 11 (6 ) ,363-371 More Information

Xie K.;Huang S.;Dong Z.;Gutman M.;Fidler I. (07-15-1995. ) Direct Correlation between Expression of Endogenous Inducible Nitric Oxide Synthase and Regression o .Cancer Research, , 55 (14 ) ,3123-3131

Xie K.;Huang S.;Dong Z.;Juang S.;Gutman M.;Xie Q.;Nathan C.;Fidler I. (04-01-1995. ) Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates m.Journal of Experimental Medicine, , 181 (4 ) ,1333-1343 More Information

Dong Z.;Yang X.;Xie K.;Juang S.;Llansa N.;Fidler I. (01-01-1995. ) Activation of inducible nitric oxide synthase gene in murine macrophages requires protein phosphatas.Journal of Leukocyte Biology, , 58 (6 ) ,725-732 More Information

Radinsky R.;Risin S.;Fan D.;Dong Z.;Bielenberg D.;Bucana C.;Fidler I. (01-01-1995. ) Level and Function of Epidermal Growth Factor Receptor Predict the Metastatic Potential of Human Col .Clinical Cancer Research, , 1 (1 ) ,19-31

Dong Z.;Radinsky R.;Fan D.;Tsan R.;Bucana C.D.;Wilmanns C.;Fidler I.J. (06-15-1994. ) Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon ca.Journal of the National Cancer Institute, , 86 (12 ) ,913-920 More Information

Fidler I.J.;Wilmanns C.;Staroselsky A.;Radinsky R.;Dong Z.;Fan D. (06-01-1994. ) Modulation of tumor cell response to chemotherapy by the organ environment.Cancer and Metastasis Reviews, , 13 (2 ) ,209-222 More Information

Xie B.;Dong Z.;Fidler I. (04-01-1994. ) Regulatory mechanisms for the expression of type IV collagenases/gelatinases in murine macrophages .Journal of Immunology, , 152 (7 ) ,3637-3644

Dong Z.;Staroselsky A.;Qi X.;Xie K.;Fidler I. (01-01-1994. ) Inverse Correlation between Expression of Inducible Nitric Oxide Synthase Activity and Production of .Cancer Research, , 54 (3 ) ,789-793

Fan D.;Poste G.;Ruffolo R.;Dong Z.;Seid C.;Earnest L.;Campbell T.;Clyne R.;Beltran P.;Fidler I. (01-01-1994. ) Circumvention of multidrug resistance in murine fibrosarcoma and colon carcinoma cells by treatment .International Journal of Oncology, , 4 (4 ) ,789-798

Killion J.;Radinsky R.;Dong Z.;Fishbeck R.;Whitworth P.;Fidler I. (11-01-1993. ) The immunogenic properties of drug-resistant murine tumor cells do not correlate with expression of .Cancer Immunology Immunotherapy, , 36 (6 ) ,381-386 More Information

Dong Z.;Qi X.;Fidler I. (04-01-1993. ) Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine .Journal of Experimental Medicine, , 177 (4 ) ,1071-1077 More Information

Dong Z.;O'Brian C.;Fidler I. (01-01-1993. ) Activation of tumoricidal properties in macrophages by lipopolysaccharide requires protein-tyrosine .Journal of Leukocyte Biology, , 53 (1 ) ,53-60 More Information

Xie K.;Huang S.;Dong Z.;Fidler I.J. (01-01-1993. ) Cytokine-induced apoptosis in transformed murine fibroblasts involves synthesis of endogenous nitric .International Journal of Oncology, , 3 (6 ) ,1043-1048

Dong Z.;Qi X.;Xie K.;Fidler I. (01-01-1993. ) Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolys .Journal of Immunology, , 151 (5 ) ,2717-2724

Bucana C.;Radinsky R.;Dong Z.;Sanchez R.;Brigati D.;Fidler I. (01-01-1993. ) A rapid colorimetric in situ mRNA hybridization technique using hyperbiotinylated oligonucleotide pr.Journal of Histochemistry and Cytochemistry, , 41 (4 ) ,499-506 More Information

O'Brian C.A.;Fan D.;Ward N.E.;Dong Z.;Iwamoto L.;Gupta K.P.;Earnest L.E.;Fidler I.J. (03-01-1991. ) Transient enhancement of multidrug resistance by the bile acid deoxycholate in murine fibrosarcoma c.Biochemical Pharmacology, , 41 (5 ) ,797-806 More Information

Dong Z.;Ward N.E.;Fan D.;Gupta K.P.;O'Brian C.A. (01-01-1991. ) In vitro model for intrinsic drug resistance: Effects of protein kinase C activators on the chemosen .Molecular Pharmacology, , 39 (4 ) ,563-569

Dong Z.;Lu S.;Zhang Y. (01-01-1989. ) Effects of Pretreatment with Protein Kinase C Activators on Macrophage Activation for Tumor Cytotoxi.Immunobiology, , 179 (4-5 ) ,382-394 More Information

Dong Z.Y.;Zhang Y.H. (01-01-1987. ) Inhibitory effect of a mycotoxin, Fusarin C, on macrophage activation and macrophage mediated cytoto .Journal of Experimental and Clinical Cancer Research, , 6 (1 ) ,31-38

Honors and Awards

1990 Science Advance Award Chinese Academy of Medical Sciences

Keywords

angiostatin, angiogenesis, IFN-b gene, prostate cancer, tumorigenicity, PCNA inhibitor, androgen receptor inhibitor, androgen receptor

Contact Information

Academic - Vontz Center for Molecular Studies
3125 Eden Avenue, Room 1308
CincinnatiĀ  Ohio, 45267-0508
Phone: 513-558-2176
Fax: 513-558-6703
zhongyun.dong@uc.edu