Caroline Freiermuth

Caroline Elizabeth Freiermuth , MD

Associate Professor of Clinical

Medical Sciences Building

COM Emergency Medicine - 0769


Bachelor of Science: Xavier University Cincinnati, Ohio, 2002 (Biology)

MD: University of Cincinnati Cincinnati, Ohio, 2006

Residency: University of Cincinnati Cincinnati, Ohio, 2010 (Emergency Medicine)

Masters of Science: Duke University Durham, NC, 2017 (Clinical Research)


American Board of Emergency Medicine (Certification Date: 06-08-2011 ) - (Recertification Date: to 01-01-2022 )

Clinical Interests

Emergency Medicine


Emergency Medicine

Research and Practice Interests

Emergency Medicine

Research Support

Grant: #A030996 / UG3HL137856 Investigators:Freiermuth, Caroline 09-07-2018 -08-31-2019 National Heart, Lung and Blood Institute A comparison of individualized vs. weight based protocols to treat vaso-occlusive episodes in Sickle Cell Disease (COMPARE VOE) Role:PI $41,387.00 Awarded Level:Federal

Grant: #A032460 / UG3HL137856 Investigators:Freiermuth, Caroline 09-20-2019 -08-31-2022 National Heart, Lung and Blood Institute A comparison of individualized vs. weight based protocols to treat vaso-occlusive episodes in Sickle Cell Disease (COMPARE VOE) Role:PI $42,671.00 Awarded Level:Federal

Grant: #AGO Contract #12545 Investigators:Brown, Jennifer; Freiermuth, Caroline; Lyons, Michael; Punches, Brittany; Stolz, Uwe 03-01-2020 -02-28-2022 Ohio Attorney General Identifying genetic markers associated with opioid use disorder Role:PI $2,738,887.00 Awarded Level:State of Ohio

Grant: #Health Collab. "COVID-19 Testing and Data Collect." (US Dept Treasury) Investigators:Calhoun, Dustin; Faryar, Kiran; Freiermuth, Caroline; Lyons, Michael; Punches, Brittany; Ryan, Richard 07-01-2020 -12-30-2020 Department of Treasury Early Intervention Program: COVID-19 Testing, Reporting, and Surveillance Role:Collaborator $7,611,499.00 Awarded Level:Federal

Grant: #EMF Research Grant Investigators:Freiermuth, Caroline 12-15-2020 -12-14-2021 Emergency Medicine Foundation Better Prescribing Better Treatment Program: Innovations to Improve Opioid Prescribing for Acute Pain Role:PI $15,000.00 Awarded Level:Private Non-Profit

Grant: #03140014EC0221 Investigators:Faryar, Kiran; Freiermuth, Caroline; Lyons, Michael; Punches, Brittany; Ryan, Richard 03-01-2021 -08-31-2022 Centers for Disease Control and Prevention UC Early Intervention Program (EIP) Role:Collaborator $1,983,000.00 Awarded Level:Federal

Grant: #03140014IN0223 Investigators:Freiermuth, Caroline; Jarrell, Kelli; Lyons, Michael; Punches, Brittany 09-30-2021 -09-29-2022 Substance Abuse & Mental Health Services Administration UC Early Intervention Program - Integrated Naloxone Access and Infrastructure (IN23) Role:PI 56000.00 Active Level:Federal


Peer Reviewed Publications

Fulton J.J.;LeBlanc T.W.;Cutson T.M.;Porter Starr K.N.;Kamal A.;Ramos K.;Freiermuth C.E.;McDuffie J.R.;Kosinski A.;Adam S.;Nagi A.;Williams J.W. (02-01-2019. ) Integrated outpatient palliative care for patients with advanced cancer: A systematic review and met.Palliative Medicine, , 33 (2 ) ,123-134 More Information

Hughes J.M.;Freiermuth C.E.;Shepherd-Banigan M.;Ragsdale L.;Eucker S.A.;Goldstein K.;Hastings S.N.;Rodriguez R.L.;Fulton J.;Ramos K.;Tabriz A.A.;Gordon A.M.;Gierisch J.M.;Kosinski A.;Williams J.W. (01-01-2019. ) Emergency Department Interventions for Older Adults: A Systematic Review.Journal of the American Geriatrics Society, , More Information

Freiermuth C.E.;Lavonas E.J.;Anderson V.E.;Kleinschmidt K.C.;Sharma K.;Rapp-Olsson M.;Gerardo C.;Bush S.;Mullins M.;Greene S.;Toschlog E.;Quackenbush E.;Rutherford Rose S.;Schwartz R.;Charlton N.;Lewis B.;Brandehoff N. (01-01-2019. ) Antivenom Treatment Is Associated with Fewer Patients using Opioids after Copperhead Envenomation.Western Journal of Emergency Medicine, , 20 (3 ) ,497-505 More Information

Kopec K.;Freiermuth C.;Maynard S.;Beuhler M. (12-01-2018. ) Dinitrophenol (DNP) Fatality Associated with a Falsely Elevated Salicylate Level: a Case Report with.Journal of Medical Toxicology, , 14 (4 ) ,323-326 More Information

Williams H.;Silva S.;Cline D.;Freiermuth C.;Tanabe P. (05-01-2018. ) Social and behavioral factors in sickle cell disease: Employment predicts decreased health care util.Journal of Health Care for the Poor and Underserved, , 29 (2 ) ,814-829 More Information

Cline D.M.;Silva S.;Freiermuth C.E.;Thornton V.;Tanabe P. (03-01-2018. ) Emergency department (ED), ED observation, day hospital, and hospital admissions for adults with sic.Western Journal of Emergency Medicine, , 19 (2 ) ,311-318 More Information

Gunn A.H.;Smothers Z.P.W.;Schramm-Sapyta N.;Freiermuth C.E.;MacEachern M.;Muzyk A.J. (01-01-2018. ) The emergency department as an opportunity for naloxone distribution.Western Journal of Emergency Medicine, , 19 (6 ) ,1036-1042 More Information

Tanabe P.;Freiermuth C.E.;Cline D.M.;Silva S. (03-01-2017. ) A prospective emergency department quality improvement project to improve the treatment of vaso-occl.Joint Commission Journal on Quality and Patient Safety, , 43 (3 ) ,116-126 More Information

Freiermuth C.E.;Silva S.;Cline D.M.;Tanabe P. (09-01-2016. ) Shift in Emergency Department Provider Attitudes Toward Patients with Sickle Cell Disease.Advanced Emergency Nursing Journal, , 38 (3 ) ,199-212 More Information

Freiermuth C.E.;Chandra A.;Peacock W.F. (01-01-2015. ) Characteristics of patients that do not initially respond to intravenous antihypertensives in the em.Western Journal of Emergency Medicine, , 16 (2 ) ,276-283 More Information

Dedert E.;McDuffie J.;Stein R.;McNiel J.;Kosinski A.;Freiermuth C.;Hemminger A.;Williams J. (01-01-2015. ) Electronic interventions for alcohol misuse and alcohol use disorders: A systematic review.Annals of Internal Medicine, , 163 (3 ) ,205-214 More Information

Thornton V.;Holl J.;Cline D.;Freiermuth C.;Sullivan D.;Tanabe P. (01-01-2014. ) Application of a proactive risk analysis to emergency department sickle cell care.Western Journal of Emergency Medicine, , 15 (4 ) ,446-458 More Information

Freiermuth C.;Haywood C.;Silva S.;Cline D.;Kayle M.;Sullivan D.;Thornton V.;Tanabe P. (01-01-2014. ) Attitudes toward patients with sickle cell disease in a multicenter sample of emergency department p.Advanced Emergency Nursing Journal, , 36 (4 ) ,335-347 More Information

Blomkalns, Andra L; O'Connell, Elise M; Eady, Caroline E; Lindsell, Christopher J; Gibler, W Brian (2006. ) Evaluation of dyslipidemia in the emergency department: impact of cholesterol testing on subsequent therapy.American heart journal, , 152 (6 ) ,1182-6 More Information