Brian Earl

Brian R. Earl

Associate Professor

Professional Summary

Initially trained as a clinical audiologist at the University of Arizona and the University of Texas Medical Branch, I am currently focusing on developing a clinical test of auditory nerve survival in an animal model of neural degeneration.  This technique was piloted as part of my dissertation and post-doctoral training at the University of Kansas.  Translation of this technique to a clinical setting may help audiologists individualize hearing aid and cochlear implant algorithms and guide future implementation of regenerative therapies. 

Education

Doctoral Degree, University of Kansas 2010 (Audiology)

Master's Degree, University of Arizona 2003 (Audiology)

Bachelor's Degree, Brigham Young University 2001 (Audiology & Speech-Language Pathology)

A.A.S., Ricks College 1997 (Spanish)

Positions and Work Experience

08-2012 - Assistant Professor, Teach courses in Audiology and conduct research focused on developing diagnostic measures of auditory nerve survival in individuals with hearing impairment. , University of Cincinnati, Department of Communication Sciences and Disorders , Cincinnati, OH

09-2010 -07-2012 Postdoctoral Fellow, Auditory Neuroscience Lab of Mark Chertoff, PhD • Participated full-time in translational research funded by two grants to Dr. Chertoff (PI) 1. Clinical measures of auditory linear/nonlinear processes, Action on Hearing Loss, UK 2. Diagnosing outer hair cell health along the cochlear partition, NIH R21/33 , University of Kansas Medical Center, Hearing and Speech Department, Kansas City, Kansas

08-2007 -07-2012 Instructor , Advanced Hearing Aids course for 2nd year graduate students focusing on the theoretical bases, techniques, and clinical application of hearing aids and their assessment, University of Kansas Medical Center, Hearing and Speech Department, Kansas City, Kansas

01-2007 -09-2010 Graduate Research Assistant, Auditory Neuroscience Lab of Mark Chertoff, PhD • Collected and analyzed data and prepared manuscript for study correlating auditory physiology with auditory nerve anatomy , University of Kansas Medical Center, Hearing and Speech Department, Kansas City, Kansas

2007 - Graduate Research Assistant, Human Auditory Research Lab of Tiffany Johnson, PhD • Recruited participants and collected data for a project examining the optimal stimulus parameters for differential diagnosis of hearing loss using distortion product otoacoustic emission measures , University of Kansas Medical Center, Hearing and Speech Department, Kansas City, Kansas

01-2007 -01-2008 Clinical Audiologist, • Provided audiologic evaluations and hearing aid services in adult clinic • Staffed monthly cleft palate clinic • Trained and supervised 2nd year AuD students , University of Kansas Medical Center, Audiology Clinic, Kansas City, Kansas

06-2003 -07-2006 Clinical Audiologist, • Provided full range of audiologic services in adult and pediatric clinics including diagnostic hearing evaluations, hearing aid fittings, auditory processing evaluations, and newborn hearing screenings in neonatal intensive care unit • Trained and supervised 4th year AuD externs • Assisted Deborah Carlson, PhD, with collection and analysis of data for study of auditory function in HIV positive patients , Univeristy of Texas Medical Branch, Center for Audiology and Speech Pathology, Galveston, Texas

2002 - Tutor , Provided tutoring services for undergraduate students with learning disabilities, University of Arizona Strategic Alternative Learning techniques Center, Tucson, Arizona

05-2002 - Graduate Research Assistant, Assisted Theodore Glattke, PhD, and Marilyn Dille, PhD, with collection and analysis of data for a study comparing distortion product and transient evoked otoacoustic emissions recorded in a noisy preschool/nursery environment, University of Arizona , Tucson, Arizona

Research and Practice Interests

My research is focused on developing diagnostic measures of auditory nerve survival in individuals with hearing impairment.  Specifying the pathophysiology leading to hearing impairment may help clinicians individualize amplification and cochlear implant algorithms.  To accomplish this objective, proof of concept experiments involving physiologic and anatomic measures are being completed in animal models of partial auditory nerve lesions.  The physiologic measures include otoacoustic emissions and auditory evoked potentials and the anatomic measures involve confocal imaging of cochlear hair cells and auditory neurons.   

Research Support

Investigators:Brian R. Earl, PhD 08-15-2012 -08-15-2014 University of Cincinnati's Vice President for Research Research Start-up Funds $85,955 Completed Level:University

Investigators:Brian R. Earl, PhD 07-01-2013 -06-30-2014 Center for Clinical and Translational Science and Training Towards a Clinical Diagnosis of Auditory Nerve Survival $25,000 Completed Type:Grant

Grant: #URC Faculty 2012-13 Investigators:Earl, Brian 05-01-2013 -06-30-2013 UC Surveying the Integrity of Neurons in the Auditory Periphery (SiNAP) Role:PI $8,000.00 Completed

Investigators:Brian Earl 2013 -2014 Hearing Health Foundation Specifying the Integrity of Neurons in the Auditory Periphery(SiNAP) Role:PI $24,998 Completed

Investigators:Brian Earl 11-01-2015 -06-30-2016 Center for Clinical and Translational Science and Training, University of Cincinnati Using Electrophysiology to Uncover Cochlear Neuropathy Role:PI $7500 Completed Type:Grant Level:University

Grant: #SRS 008636 Investigators:Earl, Brian 07-01-2013 -10-31-2014 Hearing Health Foundation Surveying the Integrity of Neurons in the Auditory Periphery Role:PI $24,998.00 Closed Level:Private Non-Profit

Grant: #UK / R56DC016585 Investigators:Earl, Brian 03-02-2018 -02-28-2019 National Institute on Deafness and Other Communication Disor Detection of noise-induced "hidden" hearing loss Role:PI $42,560.00 Awarded Level:Federal

Publications

Published Abstracts

Earl, B.R., Chertoff, M.E., & Schad, M.L. (2014. )Specifying the integrity of neurons in the auditory periphery: Influence of acoustic overexposure .[Abstract]Association for Research in Otolaryngology, Author

Kamerer, A., Chertoff, M., Peppi, M., & Earl, B.R. (2014. )Predicting outer hair cell loss:Influence of a neural contribution to the cochlear microphonic .[Abstract]Association for Reseach in Otolaryngology,

Peer Reviewed Publications

Earl, B.R., & Chertoff, M.E. (2012. )Mapping auditory nerve firing density using high-level compound action potentials and high-pass noise masking .Journal of the Acoustical Society of America, ,131 (1 ),1

Earl, B.R., & Chertoff, M.E. (2010. )Predicting auditory nerve survival using the compound action potential .Ear and Hearing, ,31 ,7

Dille, M., Glattke, T.J., & Earl, B.R. (2007. )Comparison of transient evoked otoacoustic emissions and distortion product otoacoustic emissions when screening hearing in preschool children in a community setting .InternationalJournal of Pediatric Otorhinolaryngology, ,71 ,1789

Chertoff, M.E., Earl, B.R., Diaz, F., Sorenson, J. (2012. )Using the cochlear microphonic to predict the location of missing outer hair cells .Journal of the Acoustical Society of America, ,

Chertoff, M.E., Earl, B.R., Diaz, F., Sorenson, J. (2012. )Analysis of the cochlear microphonic to a low-frequency tone embedded in filtered noise .Journal of the Acoustical Society of America, ,132 (5 ),3351-62

Earl, B.R. & Chertoff, M.E. (2013. )Amplitude of masked compund action potentials indicates location of laser-induced lesions in the auditory periphery .Association for Research Otolaryngology, ,440-441

Chertoff, Mark E; Earl, Brian R; Diaz, Francisco J; Sorensen, Janna L (2012. )Analysis of the cochlear microphonic to a low-frequency tone embedded in filtered noise.The Journal of the Acoustical Society of America, ,132 (5 ),3351-62

Earl, Brian R; Chertoff, Mark E (2012. )Mapping auditory nerve firing density using high-level compound action potentials and high-pass noise masking.The Journal of the Acoustical Society of America, ,131 (1 ),337-52

Earl, Brian R; Chertoff, Mark E (2010. )Predicting auditory nerve survival using the compound action potential.Ear and hearing, ,31 (1 ),7-21

Dille, Marilyn; Glattke, Theodore J; Earl, Brian R (2007. )Comparison of transient evoked otoacoustic emissions and distortion product otoacoustic emissions when screening hearing in preschool children in a community setting.International journal of pediatric otorhinolaryngology, ,71 (11 ),1789-95

Chertoff, Mark E; Earl, Brian R; Diaz, Francisco J; Sorensen, Janna L; Thomas, Megan L A; Kamerer, Aryn M; Peppi, Marcello (2014. )Predicting the location of missing outer hair cells using the electrical signal recorded at the round window.The Journal of the Acoustical Society of America, ,136 (3 ),1212

Clark, John Greer; Brady, Matthew; Earl, Brian R; Scheifele, Peter M; Snyder, Lianna; Clark, Suzanne Duchesne (2017. )Use of noise cancellation earphones in out-of-booth audiometric evaluations.International journal of audiology, ,56 (12 ),989-996

Liang, Chun; Earl, Brian; Thompson, Ivy; Whitaker, Kayla; Cahn, Steven; Xiang, Jing; Fu, Qian-Jie; Zhang, Fawen (2016. )Musicians Are Better than Non-musicians in Frequency Change Detection: Behavioral and Electrophysiological Evidence.Frontiers in neuroscience, ,10 ,464

Samy, Ravi N; Earl, Brian R; Lipschitz, Noga; Schweinzger, Ivy; Currier, Mark; Cripe, Timothy (2019. )Engineered oncolytic virus for the treatment of cholesteatoma: A pilot in vivo study.Laryngoscope investigative otolaryngology, ,4 (5 ),532-542

Roggia, Simone Mariotti; de França, Aline Gomes; Morata, Thais C; Krieg, Edward; Earl, Brian R (2019. )Auditory system dysfunction in Brazilian gasoline station workers.International journal of audiology, ,58 (8 ),484-496

Samy, Ravi N; Lipschitz, Noga; Earl, Brian R; Cripe, Timothy P (2019. )Evidence for Oncolytic Viral Eradication of Cholesteatoma In Vitro.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, ,160 (5 ),891-893

Invited Publications

Earl, B.R. (2004. )Contralateral suppression of spontaneous OAEs with speech & speech-like stimuli .The Hearing Journal, 57 (9 ),12

Presentations

Invited Presentations

Earl, B.R., Chertoff, M.E., Durham, D., & Martz A.N. (03-12-2009. )Uncovering the causes of hearing loss .6th Annual Capitol Graduate Research Summit, Topeka, Kansas. Other Institution. .Level:State

Earl, Brian (10-11-2011. )Kansas City Area High School Health Career Awareness Day .University of Kansas Medical Center, Kansas City, KS.

Earl, B.R. (12-17-2012. )Mapping Auditory Nerve Survival using the Masked Compound Action Potential .ENT/CSRC Lab Meeting, Cincinnati Children's Hospital Medical Center. Level:Local

Earl, B.R. (03-15-2013. )Mapping auditory nerve survival with the masked compound action potential .Ohio Speech-Language-Hearing Association Convention, Columbus, Ohio. Level:State

Earl, B.R. (12-17-2012. )Mapping auditory nerve survival using masked compound action potentials .Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. Level:Local

Earl, B.R. (03-06-2014. )What’s a hair cell to do without a neuron? .Annual Convention of the Kentucky Speech-Language-Hearing Association, Covington, Kentucky. Professional Meeting. .Level:State

Poster Presentations

Chertoff, M.E., Earl, B.R., Sorensen, J., & Durham, D. (02-2012. )Using the cochlear microphonic to estimate the location of missing outer hair cells along the cochlear partition .35th Midwinter Meeting of The Association for Research in Otolaryngology, San Diego, California. .Professional Meeting. .Level:National

Earl, B.R., Chertoff, M.E., Martz, A.N., & Ash, M.L. (11-09-2011. )Developing a diagnostic test of auditory nerve survival: Influence of cochlear outer hair cell pathology .Annual Retreat of the Kansas City Chapter of the Society for Neuroscience, Kansas City, Kansas. .Professional Meeting. .Level:Local

Earl, B.R., Chertoff, M.E., & Martz, A.N. (02-2010. )Mapping auditory nerve density using chirp stimuli and high-pass masking .33rd Midwinter Meeting of The Association for Research in Otolaryngology, Anaheim, California. .Professional Meeting. .Level:National

Earl, B.R., Chertoff, M.E., Martz, A.N., & Ash, M.L. (02-2012. )Developing a diagnostic test of auditory nerve survival: Influence of cochlear outer hair cell pathology .34th Midwinter Meeting of The Association for Research in Otolaryngology, Baltimore, Maryland. .Professional Meeting. .Level:National

Martz, A.N., Earl, B.R., Ash, M.L., & Chertoff, M.E. (02-2012. )Locating outer hair cell damage along the cochlear partition .34th Midwinter Meeting of The Association for Research in Otolaryngology, Baltimore, Maryland. .Professional Meeting. .Level:National

Martz, A.N., Earl, B.R., & Chertoff, M.E. (02-2010. )Locating outer hair cell damage using the cochlear microphonic .33rd Midwinter Meeting of The Association for Research in Otolaryngology, Anaheim, California. .Professional Meeting. .Level:National

Earl, B.R., Chertoff, M.E., Durham, D., & Martz A.N. (11-20-2009. )Predicting auditory nerve status using evoked potentials .Annual Convention of the American Speech-Language-Hearing Association, New Orleans, Louisiana. .Conference. .Level:National

Earl, B.R., Chertoff, M.E., Durham, D., & Martz A.N. (04-09-2009. )Predicting auditory nerve status using the compound action potential .Student Research Forum, University of Kansas Medical Center, Kansas City, Kansas. .Other Institution. .Level:University

Earl, B.R., Chertoff, M.E., Durham, D., & Martz A.N. (02-23-2009. )Predicting auditory nerve status using the compound action potential .Graduate Research Competition, University of Kansas, Lawrence, Kansas. .Other Institution. .Level:University

Earl, B.R., Chertoff, M.E., Durham, D., & Martz A.N. (02-2009. )Predicting auditory nerve status using the compound action potential .32nd Midwinter Meeting of The Association for Research in Otolaryngology, Baltimore, Maryland. .Professional Meeting. .Level:National

Earl, B.R., Chertoff, M.E., Durham, D., & Jacobson, D. (10-03-2008. )Estimating the number of auditory nerve fibers using the compound action potential .Annual Convention of Kansas Speech-Language-Hearing Association, Overland Park, Kansas. .Conference. .Level:State

Earl, B.R., Chertoff, M.E., Durham, D., & Jacobson, D. (04-10-2008. )Estimating the number of auditory nerve fibers using the compound action potential .Student Research Forum, University of Kansas Medical Center, Kansas City, Kansas. .Other Institution. .Level:University

Earl, B.R., Chertoff, M.E., Durham, D., & Jacobson, D. (02-2008. )Estimating the number of auditory nerve fibers using the compound action potential .31st Midwinter Meeting of The Association for Research in Otolaryngology, Phoenix, Arizona. .Professional Meeting. .Level:National

Earl, B.R. & Chertoff, M.E. (04-2013. )Specify the integrity of the neurons in the auditory periphery (SiNAP) .Anaheim Convention Center, California. .Level:National

Earl, B.R. & Chertoff, M.E. (02-2013. )Amplitude of masked compound action potentials indicates location of laser-induced lesions in the auditory periphery .Baltimore, Maryland. .

Earl, B.R. & Chertoff, M.E. (10-24-2013. )Specify the integrity of neurons in the auditory periphery (SiNAP) .University of Cincinnati Academic Health Center. .UC. .Level:University

Kamerer, A., Chertoff, M., Peppi, M., & Earl, B.R. (02-2014. )(In Press. )Predicting outer hair cell loss: Influence of a neural contribution to the cochlear microphonic. San Diego, California. .Professional Meeting. .

Liang, C., Schad, M.L., & Earl, B.R. (03-15-2014. )(In Press. )Innovating diagnosis of noise-induced hearing loss. Columbus, Ohio. .Professional Meeting. .Level:State

Liang, C., Schad, M.L., & Earl, B.R. (02-28-2014. )(In Press. )Innovating diagnosis of noise-induced hearing loss. Graduate Poster Forum, Cincinnati, Ohio. .UC. .Level:University

Tisdale, A. Zhang F., Earl B., Valencia G. (2014. )(In Press. )Establishing Normative Data for the Auditory Brainstem Response (ABR) Using the Interacoustics Eclipse. Cincinnati, Ohio. .UC. .Level:University

Paper Presentations

Earl, B.R. & Chertoff, M.E. (07-13-2012. )Mapping auditory nerve survival using the masked compound action potential .Kansas City, Kansas. Conference. Level:Regional

Earl, B.R., Chertoff, M.E., & Martz, A.N. (04-2010. )Mapping auditory nerve pathology: A non-invasive approach to an elusive diagnosis .Kansas City, Kansas. Other Institution. Level:University

Earl, B.R. (07-24-2009. )Etiologic diagnosis of sensorineural hearing loss .Omaha, Nebraska. Conference. Level:Regional

Earl, B.R. (04-02-2004. )Contralateral suppression of spontaneous otoacoustic emissions with speech and speech-like stimuli .Salt Lake City, Utah. Conference. Level:National

Honors and Awards

08-2012 -08-2014 Selected Participant University of Cincinnati New Faculty Institute Level:University

03-2011 Editor's Award for Oustanding Research in Audiology and the Hearing Sciences Ear and Hearing: The Official Journal of the American Auditory Society

02-2010 Debra L. Park Award for the Outstanding Student in Hearing Science Hearing and Speech Department, University of Kansas Medical Center,

11-2009 Student Research Travel Award Annual Convention of the American Speech-Language-Hearing Association, New Orleans, Louisiana

04-2009 First Place Award Student Research Forum Poster Session, University of Kansas Medical Center, Kansas City, Kansas

03-2009 Invited student representative University of Kansas Medical Center, School of Allied Health, 6th Annual Capitol Graduate Research Summit, Topeka, KS

02-2008 Audiologist Travel Award Association for Research in Otolaryngology

2006 -2007 First Year Graduate Fellowship University of Kansas, Lawrence, Kansas

2006 Nominated for Chancellor’s Fellowship University of Kansas, Lawrence, Kansas

04-2004 Student Research Forum Award American Academy of Audiology Convention

2001 -2003 Graduate Tuition Scholarship University of Arizona, Tucson, Arizona

1997 -1998 University Scholarship Brigham Young University, Provo, Utah

2000 -2001 University Scholarship Brigham Young University, Provo, Utah

1993 Academic Scholarship Brigham Young University-Idaho, Rexburg, Idaho

1996 -1997 Academic Scholarship Brigham Young University-Idaho, Rexburg, Idaho

Service

 American Speech-Language and Hearing Association (Convention Program Committee (Hearing Science) )Reviewer Type:Service to Professional Associations Level:National 2012

University of Kansas Medical Center (AuD Task Force )Member Type:Departmental Service Level:Department 09-2011 -07-2012

University of Kansas Medical Center (Research Advisory Council )Council Member Type:University/College Service Level:University 01-2010 -12-2010

Special Olympics (Hearing Screening Audiologist )Outside Type:Community Service Level:Local 11-2007

University of Kansas Student Speech-Language-Hearing Association (Meet the Professionals Night )Discussant Type:Service to Student Groups Level:University 04-09-2007

Galveston County Health Fair (Volunteer Audiologist )Outside Type:Community Service Level:Local 2004 -2005

Cleft Palate Clinic, Oaxaca, Mexico (Spanish Interpreter )Other Type:Community Service Level:International 02-2004

Children's Carnival, Galveston, Texas (Volunteer Audiologist )Type:Community Service Level:Local 10-25-2003

American Auditory Society Annual Meeting (Student Volunteer )Type:Service to Professional Associations Level:National 2002 -2003

Hermosillo School for the Deaf, Hermosillo, Sonora, Mexico (Student Clinician & Spanish Interpreter )Type:Community Service Level:International 2001 -2003

St. Andrew's Children's Clinic (Student Clinician & Spanish Interpreter )Type:Community Service Level:International 09-2001 -05-2003

University of Arizona Chapter of National Student Speech-Language-Hearing Association (Philanthropy Committee Chair )Type:Service to Student Groups Level:University 2002 -2003

Festival of Hope Hearing Screening, Tucson, Arizona (Student Volunteer )Type:Community Service Level:Local 10-27-2001

Program Coordinator Type:Service to Student Groups Level:University 2013

Department Liaison Type:Departmental Service Level:Regional

(Hearing Science )Committee Member Type:Service to Professional Associations Level:National 11-2012

Post Graduate Training and Education

09-2010-07-2012 Postdoctoral Fellow, Auditory Neurscience Lab of Mark Chertoff, PhD, University of Kansas Medical Center, ,Kansas City, Kansas

Keywords

Audiology, Auditory Neurophysiology

Professional Affiliation

American Speech-Language-Hearing Association CCC-A

American Academy of Audiology Fellow Member

The Association for Research in Otolaryngology Associate Member

American Auditory Society Member

Kansas Department of Health and Environment Credentialed Audiologist

Courses Taught

Medical Audiology Level:Graduate

Diagnostic Audiology Level:Graduate

-CSD-4094 HONORS IN CSD Level:Undergraduate

-CSD-4095 CAPSTONE IN CSD Level:Undergraduate

Contact Information

Academic - Department of Communication Sciences & Disorders
3225 Eden Ave.
Cincinnati  Ohio, 45267
Phone: 513-558-8770
Fax: 513-558-8500
earlbn@uc.edu