Ola Amr Elgamal, PhD

Grant: #New Idea Award Investigators:Elgamal, Ola 01-01-2025 -12-31-2025 CancerFree Kids Identify the impact of targeting DHODH on AML and immune surveillance Role:PI 50000.00 Awarded Level:Non Profit

Peer Reviewed Publications

Bray, Julie K; Elgamal, Ola A; Jiang, Jinmai; Wright, Lais S; Sutaria, Dhruvitkumar S; Badawi, Mohamed; Borcyk, Madeline G; Liu, Xiuli; Fredenburg, Kristianna M; Campbell-Thompson, Martha L; Schmittgen, Thomas D (2020. ) Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury.Cell death & disease, , 11 (2 ) ,138 More Information

Elgamal, Ola A; Mehmood, Abeera; Jeon, Jae Yoon; Carmichael, Bridget; Lehman, Amy; Orwick, Shelley J; Truxall, Jean; Goettl, Virginia M; Wasmuth, Ronni; Tran, Minh; Mitchell, Shaneice; Lapalombella, Rosa; Eathiraj, Sudharshan; Schwartz, Brian; Stegmaier, Kimberly; Baker, Sharyn D; Hertlein, Erin; Byrd, John C (2020. ) Preclinical efficacy for a novel tyrosine kinase inhibitor, ArQule 531 against acute myeloid leukemia.Journal of hematology & oncology, , 13 (1 ) ,8 More Information

Sutaria, Dhruvitkumar S; Jiang, Jinmai; Elgamal, Ola A; Pomeroy, Steven M; Badawi, Mohamed; Zhu, Xiaohua; Pavlovicz, Ryan; Azevedo-Pouly, Ana Clara P; Chalmers, Jeffrey; Li, Chenglong; Phelps, Mitch A; Schmittgen, Thomas D (2017. ) Low active loading of cargo into engineered extracellular vesicles results in inefficient miRNA mimic delivery.Journal of extracellular vesicles, , 6 (1 ) ,1333882 More Information

Zhu, Xiaohua; Badawi, Mohamed; Pomeroy, Steven; Sutaria, Dhruvitkumar S; Xie, Zhiliang; Baek, Alice; Jiang, Jinmai; Elgamal, Ola A; Mo, Xiaokui; Perle, Krista La; Chalmers, Jeffrey; Schmittgen, Thomas D; Phelps, Mitch A (2017. ) Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells.Journal of extracellular vesicles, , 6 (1 ) ,1324730 More Information

Azevedo-Pouly, Ana Clara P; Sutaria, Dhruvitkumar S; Jiang, Jinmai; Elgamal, Ola A; Amari, Foued; Allard, David; Grippo, Paul J; Coppola, Vincenzo; Schmittgen, Thomas D (2017. ) miR-216 and miR-217 expression is reduced in transgenic mouse models of pancreatic adenocarcinoma, knockout of miR-216/miR-217 host gene is embryonic lethal.Functional & integrative genomics, , 17 (2-3 ) ,203-212 More Information

Rosas, Lucia E; Elgamal, Ola A; Mo, Xiaokui; Phelps, Mitch A; Schmittgen, Thomas D; Papenfuss, Tracey L (2016. ) In vitro immunotoxicity assessment of culture-derived extracellular vesicles in human monocytes.Journal of immunotoxicology, , 13 (5 ) ,652-65 More Information

Jiang, Jinmai; Azevedo-Pouly, Ana Clara P; Redis, Roxana S; Lee, Eun Joo; Gusev, Yuriy; Allard, David; Sutaria, Dhruvitkumar S; Badawi, Mohamed; Elgamal, Ola A; Lerner, Megan R; Brackett, Daniel J; Calin, George A; Schmittgen, Thomas D (2016. ) Globally increased ultraconserved noncoding RNA expression in pancreatic adenocarcinoma.Oncotarget, , 7 (33 ) ,53165-53177 More Information

Azevedo-Pouly, Ana Clara P; Elgamal, Ola A; Schmittgen, Thomas D (2014. ) RNA isolation from mouse pancreas: a ribonuclease-rich tissue.Journal of visualized experiments : JoVE, , (90 ) ,e51779 More Information

Elgamal, Ola A; Park, Jong-Kook; Gusev, Yuriy; Azevedo-Pouly, Ana Clara P; Jiang, Jinmai; Roopra, Avtar; Schmittgen, Thomas D (2013. ) Tumor suppressive function of mir-205 in breast cancer is linked to HMGB3 regulation.PloS one, , 8 (10 ) ,e76402 More Information

Elgamal, Ola A; Fobare, Sydney; Vibhute, Sandip; Mehmood, Abeera; Vroom, Dennis C; Johnson, Mariah L; Stearns, Blaise; Lerma, James R; Truxall, Jean; Stahl, Emily; Carmichael, Bridget; Orwick, Shelley J; Mims, Alice S; Curran, Emily; Santhanam, Ramasamy; Tridandapani, Susheela; Phelps, Mitch A; Xie, Zhiliang; Coss, Christopher C; Baker, Sharyn D; Patrick, Jeffrey; Ezzell, Janel K; Rai, Jayesh; Pan, Jianmin; Rai, Shesh N; Stillwell, Cody; Wunderlich, Mark; Abdulrahim, Mouad; Goodwin, Thomas E; Hilinski, Gerard; Bennett, Chad E; Hertlein, Erin; Byrd, John C (2024. ) Pyrimidine depletion enhances targeted and immune therapy combinations in acute myeloid leukemia.JCI insight, , 9 (8 ) , More Information

Fobare, Sydney; Elgamal, Ola A; Wunderlich, Mark; Stahl, Emily; Mehmood, Abeera; Furby, Casie; Lerma, James R; Sesterhenn, Thomas M; Pan, Jianmin; Rai, Jayesh; Johnstone, Megan E; Abdul-Aziz, Amina; Johnson, Mariah L; Rai, Shesh N; Byrd, John C; Hertlein, Erin (2024. ) Inhibition of Enhancer of Zeste Homolog 2 Induces Blast Differentiation, Impairs Engraftment and Prolongs Survival in Murine Models of Acute Myeloid Leukemia.Cancers, , 16 (3 ) , More Information

Elgamal, Ola A; Fobare, Sydney; Vibhute, Sandip; Mehmood, Abeera; Vroom, Dennis C; Johnson, Mariah L; Stearns, Blaise; Lerma, James R; Truxall, Jean; Stahl, Emily; Carmichael, Bridget; Orwick, Shelley J; Mims, Alice S; Curran, Emily; Santhanam, Ramasamy; Tridandapani, Susheela; Phelps, Mitch A; Xie, Zhiliang; Coss, Christopher C; Baker, Sharyn D; Patrick, Jeffrey; Ezzell, Janel K; Rai, Jayesh; Pan, Jianmin; Rai, Shesh N; Stillwell, Cody; Wunderlich, Mark; Abdulrahim, Mouad; Goodwin, Thomas E; Hilinski, Gerard; Bennett, Chad E; Hertlein, Erin; Byrd, John C (2024. ) Pyrimidine depletion enhances targeted and immune therapy combinations in acute myeloid leukemia.JCI insight, , 9 (8 ) , More Information

Fobare, Sydney; Elgamal, Ola A; Wunderlich, Mark; Stahl, Emily; Mehmood, Abeera; Furby, Casie; Lerma, James R; Sesterhenn, Thomas M; Pan, Jianmin; Rai, Jayesh; Johnstone, Megan E; Abdul-Aziz, Amina; Johnson, Mariah L; Rai, Shesh N; Byrd, John C; Hertlein, Erin (2024. ) Inhibition of Enhancer of Zeste Homolog 2 Induces Blast Differentiation, Impairs Engraftment and Prolongs Survival in Murine Models of Acute Myeloid Leukemia.Cancers, , 16 (3 ) , More Information