Fred Finkelman

Fred D. Finkelman , MD

Professor-Emeritus

Walter A. & George McDonald Foundation Professorship of Medicine

Health Professions Building
3255 Eden Avenue
Suite 350
Cincinnati, Ohio 45267-0563
Phone (513) 558-4701
Fax (513) 558-3799
Email fred.finkelman@uc.edu

Education

Bacheolor's Degree: Queens College 1967 (Biology)

Medical Degree: Yale University School of Medicine 1971

Internship : Yale-New Haven Hospital 1972 (Internal Medicine )

Junior Assistant Resident : Yale-New Haven Hospital 1973 (Internal Medicine )

Fellowship: University of Texas Health Science Center at Dallas 1977 (Rheumatology Section, Department of Internal Medicine )

Certifications

American Board of Internal Medicine (Certification Date: 06-16-1976 )

American Board of Internal Medicine (Rheumatology) (Certification Date: 06-17-1980 )

Research and Practice Interests

Basic and Disease-related Immunology, Cytokines, Interleukin-4 Gastrointestinal Nematode Infections, Asthma Regulated by Cytokines, in Vivo Mouse Systems and  B cell Membrane Immunoglobulin Crosslinking, T Cell Help and B Cell Survival.

Positions and Work Experience

1973 -1975 Research Associate, Laboratory of Immunology, NIAID, NIH,

1977 -1980 Assistant Professor, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD

1980 -1986 Associate Professor, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD

1984 -1985 Director, Division of Rheumatology, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD

1986 -1995 Professor, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD

1995 -2005 Director, Division of Immunology, University of Cincinnati College of Medicine, Cincinnati, OH

1995 -To Present McDonald Professor of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH

1995 -To Present Director, Rheumatology Division, Cincinnati Veterans Administration Medical Center, Cincinnati, OH

2001 -To Present Professor of Pediatrics, Division of Immunobiology, University of Cincinnati College of Medicine and Children's Hospital Medical Research Foundation, Cincinnati, OH

Research Support

12-2007 -11-2011 United States Veterans Authority Merit Award Pathogenesis and Prevention of Anaphylaxis induced by Ingested Antigens $125,000

Grant: #P01 HL076383 07-01-2004 -06-30-2010 NIH/NIHLBI Project 2: "Unique Effects of IL-13 in Asthma: A Mechanistic Analysis"

Grant: #R01AI072040 09-2007 -08-2012 NIH/NIAID IGG Isotype Regulation of Antibody - Media TED Disorders $250,000

Grant: #R01HL097360 10-2009 -09-2011 NIH/NHLBI Direct IL-4 and IL-13 Effects on Pulmonary Smooth Muscle in Allergic Airway Disease $300,000

Grant: #R01AI070300 12-2007 -11-2012 NIH/NIAID Regulation of CD8+ T Cell Homeostasis by IL-4 $250,000

Grant: #R21AI079947 07-01-2008 -06-30-2010 NIH/NIAID Mechanism of Peanut Allergenicity $125,000

Grant: #R01GM083204 Investigators:D Herbert, F Finkelman 12-01-2007 -11-30-2012 NIH/NIGMS Alternative Macrophage Activation Limits Immunopathology Role:Co-I $250,000

Grant: #CHMC 516 Investigators:Finkelman, Fred 07-01-2006 -06-30-2007 Cincinnati Children's Hospital Medical Center Biology of Response to TNF Blockade in JRA Role:PI $9,739.00 Closed Level:Private Non-Profit

Grant: #SRS 001924 Investigators:Finkelman, Fred 01-01-2007 -12-31-2008 Plexxikon Inc. Evaluation of Enzyme Inhibitors in Anaphylaxis Role:PI $83,592.00 Closed Level:Industry

Grant: #R01-AI-52099 Investigators:Finkelman, Fred 05-15-2003 -04-30-2009 National Institute of Allergy and Infectious Diseases Cellular Targets of IL-4 and IL-13 in Worm Expulsion Role:PI $1,607,561.16 Closed Level:Federal

Grant: #R01-AI-055848 Investigators:Finkelman, Fred 07-01-2003 -12-31-2007 National Institute of Allergy and Infectious Diseases Role of Inflammatory Cytokins in the Allergic Response Role:PI $1,212,052.00 Closed Level:Federal

Investigators:Finkelman, Fred 02-01-2005 -01-31-2007 Food Allergy and Anaphylaxis Network Pathophysiology of Local and Systemic Food Allergy in A Mouse Model Role:PI $150,000.00 Closed Level:Private Non-Profit

Grant: #5-R01-AI-37180-04-A0-S0-E0 Investigators:Finkelman, Fred 08-01-1995 -07-31-1999 National Institute of Allergy and Infectious Diseases Cytokine Enhancement of an Anti-Nematode Vaccine Role:PI $431,114.00 Closed Level:Federal

Grant: #ARTH-101-03-A0-S0-E0 Investigators:Finkelman, Fred 08-01-1995 -07-31-1999 Arthritis Foundation Effects of Membrane Ig Crosslinking on the Lifespan of Mature B Cells In Vivo Role:PI $225,000.00 Closed Level:Private Non-Profit

Grant: #5-R01-AI-35987-10-A0-S0-E0 Investigators:Finkelman, Fred 12-01-1998 -11-30-2004 National Institute of Allergy and Infectious Diseases Role of IL-4R in Immunity to Gastrointestinal Nematode Parasites Role:PI $1,004,326.00 Closed Level:Federal

Grant: #5-R01-AI-44971-04-A0-S0-E0 Investigators:Finkelman, Fred 03-01-1999 -02-28-2004 National Institute of Allergy and Infectious Diseases Regulation of IL-4 Production In Vivo Role:PI $724,075.00 Closed Level:Federal

Grant: #AF-07-03-A0-S0-E0 Investigators:Finkelman, Fred 07-01-1999 -06-30-2002 Arthritis Foundation Regulation of Tolerance and Immunity by Antigen-Presenting Dendritic Cells Role:PI $267,605.00 Closed Level:Private Non-Profit

Grant: #5-R01-AI-45766-05-A0-S0-E0 Investigators:Finkelman, Fred 09-01-1999 -07-31-2005 National Institute of Allergy and Infectious Diseases Cytokine Regulation of a Mouse Model of Asthma Role:PI $1,209,386.00 Closed Level:Federal

Grant: #5-R21-AI-46972-02-A0-S0-E0 Investigators:Finkelman, Fred 09-30-1999 -09-29-2002 National Institute of Allergy and Infectious Diseases A Serum Assay for In Vivo Cytokine Production Role:PI $378,000.00 Closed Level:Federal

Grant: #R01 AI072040 Investigators:Finkelman, Fred; Herbert, Debroski 08-15-2007 -07-31-2013 National Institute of Allergy and Infectious Diseases IgG Isotype Regulation of Antibody-Mediated Disorders Role:PI $1,925,323.00 Active Level:Federal

Grant: #R01-GM083204 Investigators:Finkelman, Fred; Herbert, Debroski 09-30-2007 -07-31-2012 National Institute of General Medical Sciences Macrophages Downmodulate Lethal Pathology Role:Collaborator $661,500.00 Closed Level:Federal

Grant: #200712551 Investigators:Finkelman, Fred 08-05-2007 -08-04-2009 Amgen, Inc Amgen Master Agreement Role:PI $.00 Closed Level:Industry

Grant: #R01 AI070300 Investigators:Finkelman, Fred; Herbert, Debroski; Morris, Suzanne 01-15-2008 -12-31-2013 National Institute of Allergy and Infectious Diseases Regulation of CD8+ TCell Homeostasis by IL-4 Role:PI $1,930,578.00 Active Level:Federal

Grant: #R21 AI079947 Investigators:Finkelman, Fred; Khodoun, Marat 06-18-2008 -05-31-2010 National Institute of Allergy and Infectious Diseases Identification Of Proteins Responsible For Peanut Allergenicity Role:PI $429,000.00 Closed Level:Federal

Grant: #SRS 006447 Investigators:Finkelman, Fred 01-29-2009 -01-14-2010 Abbott Laboratories Mechanism of the Efficacy of Anti-IL-13 Role:PI $21,325.00 Closed Level:Industry

Grant: #R21AI103816 Investigators:Denson, Lee; Finkelman, Fred; Khodoun, Marat 07-01-2012 -06-30-2014 National Institute of Allergy and Infectious Diseases Human IgG-mediated Anaphylaxis Role:PI $425,647.00 Active Level:Federal

Grant: #CFBRE 00100 sub W81XWH-13-1-0497 Investigators:Finkelman, Fred; Khodoun, Marat 09-30-2013 -09-29-2016 Department of the Army Research, Development and Engineering Command Induction of food allergy by inhaled allergen Role:Collaborator $104,381.00 Active Level:Federal

Grant: #R01 AI113162 Investigators:Finkelman, Fred 07-15-2014 -06-30-2018 National Institute of Allergy and Infectious Diseases Suppression of IgE-Mediated Disease by Polyclonal Rapid Desensitization Role:PI $337,775.00 Awarded Level:Federal

Grant: #Research Agreement Investigators:Finkelman, Fred; Khodoun, Marat; Morris, Suzanne 06-01-2014 -05-31-2017 Food Allergy Research & Education, Inc. Rapid suppression of food allergy with anti-Fc epsilon RI alpha antibody Role:PI $734,986.00 Awarded Level:Private Non-Profit

Grant: #R01AI130103 Investigators:Finkelman, Fred; Khodoun, Marat 01-25-2017 -12-31-2021 National Institute of Allergy and Infectious Diseases Wimpy antibody isotypes protect against antibody-mediated disease Role:PI $371,842.00 Active Level:Federal

Grant: #CHMC 136674 sub R01AI112626 Investigators:Finkelman, Fred 05-01-2016 -04-30-2017 National Institute of Allergy and Infectious Diseases Food Allergy and Goblet Cell Antigen Passages Role:PI $3,465.00 Active Level:Federal

Grant: #135643 / W81XWH-15-1-0517 Investigators:Finkelman, Fred 09-30-2016 -09-29-2017 Department of the Army Medical Research Acquisition Activity IL-9-Producing Mast Cell Precursors and Food Allergy Role:PI $11,654.00 Awarded Level:Federal

Grant: #CHMC 135743 sub R01AI112626 Investigators:Finkelman, Fred 05-01-2016 -04-30-2017 National Institute of Allergy and Infectious Diseases Food Allergy and Goblet Cell Antigen Passages Role:PI $3,465.00 Closed Level:Federal

Grant: #20116901 / R01 AI135191 Investigators:Finkelman, Fred 05-15-2018 -04-30-2023 National Institute of Allergy and Infectious Diseases Regulation of gene expression in the anaphylactic pathway Role:PI $15,861.00 Awarded Level:Federal

Grant: #SUBK00009418 / AI112626 Investigators:Finkelman, Fred 05-10-2018 -04-30-2020 National Institute of Allergy and Infectious Diseases Food Allergy and Goblet Cell Antigen Passages Role:PI $9,782.00 Active Level:Federal

Grant: #R01DK116789 Investigators:Finkelman, Fred; Shao, Wenhai; Soleimani, Manoocher 04-01-2019 -03-31-2022 National Inst of Diabetes and Digestive and Kidney Disease Axl receptor tyrosine kinase, a potential therapeutic target in glomerulonephritis Role:Collaborator $240,565.00 Awarded Level:Federal

Grant: #R01AI145991 Investigators:Finkelman, Fred; Khodoun, Marat; Morris, Suzanne 07-05-2018 -06-30-2024 National Institute of Allergy and Infectious Diseases Rapid, safe suppression of IgE-mediated disease with monovalent anti-FceRIa mAb Role:PI $383,995.00 Awarded Level:Federal

Grant: #R01 AI145991 Investigators:Finkelman, Fred; Khodoun, Marat; Morris, Suzanne 07-05-2019 -06-30-2024 National Institute of Allergy and Infectious Diseases Rapid, safe suppression of IgE-mediated disease with monovalent anti-FceRIa mAb Role:PI $383,995.00 Awarded Level:Federal

Grant: #tba; R01AI182277 Investigators:Finkelman, Fred; Morris, Suzanne 12-02-2024 -11-30-2029 National Institute of Allergy and Infectious Diseases Mast Cell Lineage Commitment and Function Role:PI 29219.61 Hold Level:Federal

Publications

Peer Reviewed Publications

Zhen, Yuxuan; Smith, Roger D; Finkelman, Fred D; Shao, Wen-Hai (2020. ) Ezh2-mediated epigenetic modification is required for allogeneic T cell-induced lupus disease.Arthritis research & therapy, , 22 (1 ) ,133 More Information

Khodoun, Marat V; Morris, Suzanne C; Angerman, Elizabeth; Potter, Crystal; Schuman, Richard; Wunderlich, Mark; Maciag, Joseph J; Sullivan Locker, Kathryn C; Mulloy, James C; Herr, Andrew B; Finkelman, Fred D (2020. ) Rapid desensitization of humanized mice with anti-human Fc?RI? monoclonal antibodies.The Journal of allergy and clinical immunology, , 145 (3 ) ,907-921.e3 More Information

McKnight, Christopher G; Potter, Crystal; Finkelman, Fred D (2020. ) IL-4R? expression by airway epithelium and smooth muscle accounts for nearly all airway hyperresponsiveness in murine allergic airway disease.Mucosal immunology, , 13 (2 ) ,283-292 More Information

Rathod, Sanjay; Ramsey, Manda; DiGiorgio, Danielle; Berrios, Roberto; Finkelman, Fred D; Fernandez, Christian A (2019. ) Asparaginase immune complexes induce Fc-?RIII-dependent hypersensitivity in naive mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, , 33 (10 ) ,10996-11005 More Information

Leyva-Castillo, Juan-Manuel; Galand, Claire; Kam, Christy; Burton, Oliver; Gurish, Michael; Musser, Melissa A; Goldsmith, Jeffrey D; Hait, Elizabeth; Nurko, Samuel; Brombacher, Frank; Dong, Chen; Finkelman, Fred D; Lee, Richard T; Ziegler, Steven; Chiu, Isaac; Austen, K Frank; Geha, Raif S (2019. ) Mechanical Skin Injury Promotes Food Anaphylaxis by Driving Intestinal Mast Cell Expansion.Immunity, , 50 (5 ) ,1262-1275.e4 More Information

Dey, Anup; Yang, Wenjing; Gegonne, Anne; Nishiyama, Akira; Pan, Richard; Yagi, Ryoji; Grinberg, Alex; Finkelman, Fred D; Pfeifer, Karl; Zhu, Jinfang; Singer, Dinah; Zhu, Jun; Ozato, Keiko (2019. ) BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses.The EMBO journal, , 38 (7 ) , More Information

Rathod, Sanjay; Ramsey, Manda; Relling, Mary V; Finkelman, Fred D; Fernandez, Christian A (2019. ) Hypersensitivity reactions to asparaginase in mice are mediated by anti-asparaginase IgE and IgG and the immunoglobulin receptors Fc?RI and Fc?RIII.Haematologica, , 104 (2 ) ,319-329 More Information

Li, Yapeng; Liu, Bing; Harmacek, Laura; Long, Zijie; Liang, Jinyi; Lukin, Kara; Leach, Sonia M; O'Connor, Brian; Gerber, Anthony N; Hagman, James; Roers, Axel; Finkelman, Fred D; Huang, Hua (2018. ) The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis.The Journal of allergy and clinical immunology, , 142 (4 ) ,1173-1184 More Information

Yamani, Amnah; Wu, David; Waggoner, Lisa; Noah, Taeko; Koleske, Anthony J; Finkelman, Fred; Hogan, Simon P (2018. ) The vascular endothelial specific IL-4 receptor alpha-ABL1 kinase signaling axis regulates the severity of IgE-mediated anaphylactic reactions.The Journal of allergy and clinical immunology, , 142 (4 ) ,1159-1172.e5 More Information

Zhen, Yuxuan; Lee, Iris J; Finkelman, Fred D; Shao, Wen-Hai (2018. ) Targeted inhibition of Axl receptor tyrosine kinase ameliorates anti-GBM-induced lupus-like nephritis.Journal of autoimmunity, , 93 ,37-44 More Information

Schlaudecker, Elizabeth P; Ambroggio, Lilliam; McNeal, Monica M; Finkelman, Fred D; Way, Sing Sing (2018. ) Declining responsiveness to influenza vaccination with progression of human pregnancy.Vaccine, , 36 (31 ) ,4734-4741 More Information

Huang, Hua; Li, Yapeng; Liang, Jinyi; Finkelman, Fred D (2018. ) Molecular Regulation of Histamine Synthesis.Frontiers in immunology, , 9 ,1392 More Information

Clay, Corey D; Strait, Richard T; Mahler, Ashley; Khodoun, Marat V; Finkelman, Fred D (2018. ) Anti-Fc?RIIB mAb suppresses murine IgG-dependent anaphylaxis by Fc domain targeting of Fc?RIII.The Journal of allergy and clinical immunology, , 141 (4 ) ,1373-1381.e5 More Information

Zhen, Yuxuan; Finkelman, Fred D; Shao, Wen-Hai (2018. ) Mechanism of Mer receptor tyrosine kinase inhibition of glomerular endothelial cell inflammation.Journal of leukocyte biology, , 103 (4 ) ,709-717 More Information

Martin, Rebecca K; Damle, Sheela R; Valentine, Yolander A; Zellner, Matthew P; James, Briana N; Lownik, Joseph C; Luker, Andrea J; Davis, Elijah H; DeMeules, Martha M; Khandjian, Laura M; Finkelman, Fred D; Urban, Joseph F; Conrad, Daniel H (2018. ) B1 Cell IgE Impedes Mast Cell-Mediated Enhancement of Parasite Expulsion through B2 IgE Blockade.Cell reports, , 22 (7 ) ,1824-1834 More Information

Epp, Alexandra; Hobusch, Juliane; Bartsch, Yannic C; Petry, Janina; Lilienthal, Gina-Maria; Koeleman, Carolien A M; Eschweiler, Simon; Möbs, Christian; Hall, Ashley; Morris, Suzanne C; Braumann, Dominique; Engellenner, Christine; Bitterling, Josephine; Rahmöller, Johann; Leliavski, Alexei; Thurmann, Robina; Collin, Mattias; Moremen, Kelley W; Strait, Richard T; Blanchard, Véronique; Petersen, Arnd; Gemoll, Timo; Habermann, Jens K; Petersen, Frank; Nandy, Andreas; Kahlert, Helga; Hertl, Michael; Wuhrer, Manfred; Pfützner, Wolfgang; Jappe, Uta; Finkelman, Fred D; Ehlers, Marc (2018. ) Sialylation of IgG antibodies inhibits IgG-mediated allergic reactions.The Journal of allergy and clinical immunology, , 141 (1 ) ,399-402.e8 More Information

Khodoun, Marat V; Tomar, Sunil; Tocker, Joel E; Wang, Yui Hsi; Finkelman, Fred D (2018. ) Prevention of food allergy development and suppression of established food allergy by neutralization of thymic stromal lymphopoietin, IL-25, and IL-33.The Journal of allergy and clinical immunology, , 141 (1 ) ,171-179.e1 More Information

McKnight, Christopher G; Jude, Joseph A; Zhu, Zhenqi; Panettieri, Reynold A; Finkelman, Fred D (2017. ) House Dust Mite-Induced Allergic Airway Disease Is Independent of IgE and Fc?RI?.American journal of respiratory cell and molecular biology, , 57 (6 ) ,674-682 More Information

McKnight, Christopher G; Morris, Suzanne C; Perkins, Charles; Zhu, Zhenqi; Hildeman, David A; Bendelac, Albert; Finkelman, Fred D (2017. ) NKT cells contribute to basal IL-4 production but are not required to induce experimental asthma.PloS one, , 12 (11 ) ,e0188221 More Information

Via, Charles S; Soloviova, Kateryna; Puliaiev, Maksym; Puliav, Roman; Puliaeva, Irina; Morris, Suzanne C; Finkelman, Fred D (2017. ) In vivo IL-4 prevents allo-antigen driven CD8+ CTL development.Clinical immunology (Orlando, Fla.), , 180 ,11-24 More Information

Finkelman, Fred D (2017. ) Identification of IgE as the Allergy-Associated Ig Isotype.Journal of immunology (Baltimore, Md. : 1950), , 198 (1 ) ,3-4 More Information

Minar, Phillip; Jackson, Kimberly; Tsai, Yi-Ting; Rosen, Michael J; Northcutt, Michael; Khodoun, Marat; Finkelman, Fred D; Denson, Lee A (2016. ) A Low Neutrophil CD64 Index Is Associated with Sustained Remission During Infliximab Maintenance Therapy.Inflammatory bowel diseases, , 22 (11 ) ,2641-2647 More Information

Galand, Claire; Leyva-Castillo, Juan Manuel; Yoon, Juhan; Han, Alex; Lee, Margaret S; McKenzie, Andrew N J; Stassen, Michael; Oyoshi, Michiko K; Finkelman, Fred D; Geha, Raif S (2016. ) IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cells.The Journal of allergy and clinical immunology, , 138 (5 ) ,1356-1366 More Information

Tripathi, Pulak; Morris, Suzanne C; Perkins, Charles; Sholl, Allyson; Finkelman, Fred D; Hildeman, David A (2016. ) IL-4 and IL-15 promotion of virtual memory CD8+ T cells is determined by genetic background.European journal of immunology, , 46 (10 ) ,2333-2339 More Information

Strait, Richard T; Thornton, Sherry; Finkelman, Fred D (2016. ) C?1 Deficiency Exacerbates Collagen-Induced Arthritis.Arthritis & rheumatology (Hoboken, N.J.), , 68 (7 ) ,1780-7 More Information

Küçükerden, Melike; Huda, Ruksana; Tüzün, Erdem; Y?lmaz, Abdullah; Skriapa, Lamprini; Trakas, Nikos; Strait, Richard T; Finkelman, Fred D; Kabaday?, Sevil; Zisimopoulou, Paraskevi; Tzartos, Socrates; Christadoss, Premkumar (2016. ) MuSK induced experimental autoimmune myasthenia gravis does not require IgG1 antibody to MuSK.Journal of neuroimmunology, , 295-296 ,84-92 More Information

Finkelman, Fred D; Khodoun, Marat V; Strait, Richard (2016. ) Human IgE-independent systemic anaphylaxis.The Journal of allergy and clinical immunology, , 137 (6 ) ,1674-1680 More Information

Wawrzyniak, Paulina; Akdis, Cezmi A; Finkelman, Fred D; Rothenberg, Marc E (2016. ) Advances and highlights in mechanisms of allergic disease in 2015.The Journal of allergy and clinical immunology, , 137 (6 ) ,1681-1696 More Information

Gieras, Anna; Linhart, Birgit; Roux, Kenneth H; Dutta, Moumita; Khodoun, Marat; Zafred, Domen; Cabauatan, Clarissa R; Lupinek, Christian; Weber, Milena; Focke-Tejkl, Margarete; Keller, Walter; Finkelman, Fred D; Valenta, Rudolf (2016. ) IgE epitope proximity determines immune complex shape and effector cell activation capacity.The Journal of allergy and clinical immunology, , 137 (5 ) ,1557-65 More Information

Kulkarni, Upasana; Karsten, Christian M; Kohler, Thomas; Hammerschmidt, Sven; Bommert, Kurt; Tiburzy, Benjamin; Meng, Lingzhang; Thieme, Lara; Recke, Andreas; Ludwig, Ralf J; Pollok, Karolin; Kalies, Kathrin; Bogen, Bjarne; Boettcher, Martin; Kamradt, Thomas; Hauser, Anja E; Langer, Christian; Huber-Lang, Markus; Finkelman, Fred D; Köhl, Jörg; Wong, David M; Manz, Rudolf Armin (2016. ) IL-10 mediates plasmacytosis-associated immunodeficiency by inhibiting complement-mediated neutrophil migration.The Journal of allergy and clinical immunology, , 137 (5 ) ,1487-1497.e6 More Information

Lee, Jee-Boong; Chen, Chun-Yu; Liu, Bo; Mugge, Luke; Angkasekwinai, Pornpimon; Facchinetti, Valeria; Dong, Chen; Liu, Yong-Jun; Rothenberg, Marc E; Hogan, Simon P; Finkelman, Fred D; Wang, Yui-Hsi (2016. ) IL-25 and CD4(+) TH2 cells enhance type 2 innate lymphoid cell-derived IL-13 production, which promotes IgE-mediated experimental food allergy.The Journal of allergy and clinical immunology, , 137 (4 ) ,1216-1225.e5 More Information

Karo-Atar, D; Bordowitz, A; Wand, O; Pasmanik-Chor, M; Fernandez, I E; Itan, M; Frenkel, R; Herbert, D R; Finkelman, F D; Eickelberg, O; Munitz, A (2016. ) A protective role for IL-13 receptor ? 1 in bleomycin-induced pulmonary injury and repair.Mucosal immunology, , 9 (1 ) ,240-53 More Information

Chen, Chun-Yu; Lee, Jee-Boong; Liu, Bo; Ohta, Shoichiro; Wang, Pin-Yi; Kartashov, Andrey V; Mugge, Luke; Abonia, J Pablo; Barski, Artem; Izuhara, Kenji; Rothenberg, Marc E; Finkelman, Fred D; Hogan, Simon P; Wang, Yui-Hsi (2015. ) Induction of Interleukin-9-Producing Mucosal Mast Cells Promotes Susceptibility to IgE-Mediated Experimental Food Allergy.Immunity, , 43 (4 ) ,788-802 More Information

Wheatley, Lisa M; Plaut, Marshall; Schwaninger, Julie M; Banerji, Aleena; Castells, Mariana; Finkelman, Fred D; Gleich, Gerald J; Guttman-Yassky, Emma; Mallal, Simon A K; Naisbitt, Dean J; Ostrov, David A; Phillips, Elizabeth J; Pichler, Werner J; Platts-Mills, Thomas A E; Roujeau, Jean-Claude; Schwartz, Lawrence B; Trepanier, Lauren A (2015. ) Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy.The Journal of allergy and clinical immunology, , 136 (2 ) ,262-71.e2 More Information

McAlees, J W; Whitehead, G S; Harley, I T W; Cappelletti, M; Rewerts, C L; Holdcroft, A M; Divanovic, S; Wills-Karp, M; Finkelman, F D; Karp, C L; Cook, D N (2015. ) Distinct Tlr4-expressing cell compartments control neutrophilic and eosinophilic airway inflammation.Mucosal immunology, , 8 (4 ) ,863-73 More Information

Huda, Ruksana; Strait, Richard T; Tüzün, Erdem; Finkelman, Fred D; Christadoss, Premkumar (2015. ) IgG1 deficiency exacerbates experimental autoimmune myasthenia gravis in BALB/c mice.Journal of neuroimmunology, , 281 ,68-72 More Information

Fernandez, Christian A; Smith, Colton; Karol, Seth E; Ramsey, Laura B; Liu, Chengcheng; Pui, Ching-Hon; Jeha, Sima; Evans, William E; Finkelman, Fred D; Relling, Mary V (2015. ) Effect of premedications in a murine model of asparaginase hypersensitivity.The Journal of pharmacology and experimental therapeutics, , 352 (3 ) ,541-51 More Information

Strait, Richard T; Posgai, Monica T; Mahler, Ashley; Barasa, Nathaniel; Jacob, Chaim O; Köhl, Jörg; Ehlers, Marc; Stringer, Keith; Shanmukhappa, Shiva Kumar; Witte, David; Hossain, Md Monir; Khodoun, Marat; Herr, Andrew B; Finkelman, Fred D (2015. ) IgG1 protects against renal disease in a mouse model of cryoglobulinaemia.Nature, , 517 (7535 ) ,501-4 More Information

Song, Ying; Liu, Changda; Hui, Yiqun; Srivastava, Kamal; Zhou, Zhenwen; Chen, Jia; Miller, Rachel L; Finkelman, Fred D; Li, Xiu-Min (2014. ) Maternal allergy increases susceptibility to offspring allergy in association with TH2-biased epigenetic alterations in a mouse model of peanut allergy.The Journal of allergy and clinical immunology, , 134 (6 ) ,1339-1345.e7 More Information

Shirey, Kari Ann; Lai, Wendy; Pletneva, Lioubov M; Finkelman, Fred D; Feola, David J; Blanco, Jorge C G; Vogel, Stefanie N (2014. ) Agents that increase AAM differentiation blunt RSV-mediated lung pathology.Journal of leukocyte biology, , 96 (6 ) ,951-5 More Information

Shao, Wen-Hai; Zhen, Yuxuan; Finkelman, Fred D; Cohen, Philip L (2014. ) The Mertk receptor tyrosine kinase promotes T-B interaction stimulated by IgD B-cell receptor cross-linking.Journal of autoimmunity, , 53 ,78-84 More Information

Finkelman, Fred D (2014. ) Diesel exhaust particle exposure during pregnancy promotes development of asthma and atopy.The Journal of allergy and clinical immunology, , 134 (1 ) ,73-4 More Information

Ulusoy, Canan; Kim, Eunmi; Tüzün, Erdem; Huda, Ruksana; Y?lmaz, Vuslat; Poulas, Konstantinos; Trakas, Nikos; Skriapa, Lamprini; Niarchos, Athanasios; Strait, Richard T; Finkelman, Fred D; Turan, Selin; Zisimopoulou, Paraskevi; Tzartos, Socrates; Saruhan-Direskeneli, Güher; Christadoss, Premkumar (2014. ) Preferential production of IgG1, IL-4 and IL-10 in MuSK-immunized mice.Clinical immunology (Orlando, Fla.), , 151 (2 ) ,155-63 More Information

Khodoun, Marat V; Kucuk, Zeynep Yesim; Strait, Richard T; Krishnamurthy, Durga; Janek, Kevin; Clay, Corey D; Morris, Suzanne C; Finkelman, Fred D (2013. ) Rapid desensitization of mice with anti-Fc?RIIb/Fc?RIII mAb safely prevents IgG-mediated anaphylaxis.The Journal of allergy and clinical immunology, , 132 (6 ) ,1375-87 More Information

Chen, Weiguo; Sivaprasad, Umasundari; Gibson, Aaron M; Ericksen, Mark B; Cunningham, Christie M; Bass, Stacey A; Kinker, Kayla G; Finkelman, Fred D; Wills-Karp, Marsha; Khurana Hershey, Gurjit K (2013. ) IL-13 receptor ?2 contributes to development of experimental allergic asthma.The Journal of allergy and clinical immunology, , 132 (4 ) ,951-8.e1-6 More Information

Khodoun, Marat V; Kucuk, Zeynep Yesim; Strait, Richard T; Krishnamurthy, Durga; Janek, Kevin; Lewkowich, Ian; Morris, Suzanne C; Finkelman, Fred D (2013. ) Rapid polyclonal desensitization with antibodies to IgE and Fc?RI?.The Journal of allergy and clinical immunology, , 131 (6 ) ,1555-64 More Information

Kumar, Sachin; Xu, Juying; Perkins, Charles; Guo, Fukun; Snapper, Scott; Finkelman, Fred D; Zheng, Yi; Filippi, Marie-Dominique (2012. ) Cdc42 regulates neutrophil migration via crosstalk between WASp, CD11b, and microtubules.Blood, , 120 (17 ) ,3563-74 More Information

Hogan, Simon P; Wang, Yui Hsi; Strait, Richard; Finkelman, Fred D (2012. ) Food-induced anaphylaxis: mast cells as modulators of anaphylactic severity.Seminars in immunopathology, , 34 (5 ) ,643-53 More Information

Munitz, Ariel; Cole, Eric T; Karo-Atar, Danielle; Finkelman, Fred D; Rothenberg, Marc E (2012. ) Resistin-like molecule-? regulates IL-13-induced chemokine production but not allergen-induced airway responses.American journal of respiratory cell and molecular biology, , 46 (5 ) ,703-13 More Information

Kucuk, Zeynep Yesim; Strait, Richard; Khodoun, Marat V; Mahler, Ashley; Hogan, Simon; Finkelman, Fred D (2012. ) Induction and suppression of allergic diarrhea and systemic anaphylaxis in a murine model of food allergy.The Journal of allergy and clinical immunology, , 129 (5 ) ,1343-8 More Information

Ahrens, Richard; Osterfeld, Heather; Wu, David; Chen, Chun-Yu; Arumugam, Muthuvel; Groschwitz, Katherine; Strait, Richard; Wang, Yui-Hsi; Finkelman, Fred D; Hogan, Simon P (2012. ) Intestinal mast cell levels control severity of oral antigen-induced anaphylaxis in mice.The American journal of pathology, , 180 (4 ) ,1535-46 More Information

Wills-Karp, Marsha; Rani, Reena; Dienger, Krista; Lewkowich, Ian; Fox, James G; Perkins, Charles; Lewis, Lauren; Finkelman, Fred D; Smith, Dirk E; Bryce, Paul J; Kurt-Jones, Evelyn A; Wang, Timothy C; Sivaprasad, Umasundari; Hershey, Gurjit K; Herbert, De'Broski R (2012. ) Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection.The Journal of experimental medicine, , 209 (3 ) ,607-22 More Information

Allen, Jessica L; Flick, Leah M; Divanovic, Senad; Jackson, Shaun W; Bram, Richard; Rawlings, David J; Finkelman, Fred D; Karp, Christopher L (2012. ) Cutting edge: regulation of TLR4-driven B cell proliferation by RP105 is not B cell autonomous.Journal of immunology (Baltimore, Md. : 1950), , 188 (5 ) ,2065-9 More Information

Strait, Richard T; Hicks, Wyenona; Barasa, Nathaniel; Mahler, Ashley; Khodoun, Marat; Köhl, Jörg; Stringer, Keith; Witte, David; Van Rooijen, Nico; Susskind, Brian M; Finkelman, Fred D (2011. ) MHC class I-specific antibody binding to nonhematopoietic cells drives complement activation to induce transfusion-related acute lung injury in mice.The Journal of experimental medicine, , 208 (12 ) ,2525-44 More Information

Khodoun, Marat V; Strait, Richard; Armstrong, Laura; Yanase, Noriko; Finkelman, Fred D (2011. ) Identification of markers that distinguish IgE- from IgG-mediated anaphylaxis.Proceedings of the National Academy of Sciences of the United States of America, , 108 (30 ) ,12413-8 More Information

Wu, David; Ahrens, Richard; Osterfeld, Heather; Noah, Taeko K; Groschwitz, Katherine; Foster, Paul S; Steinbrecher, Kris A; Rothenberg, Marc E; Shroyer, Noah F; Matthaei, Klaus I; Finkelman, Fred D; Hogan, Simon P (2011. ) Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion.The Journal of biological chemistry, , 286 (15 ) ,13357-69 More Information

Perkins, Charles; Yanase, Noriko; Smulian, George; Gildea, Lucy; Orekov, Tatyana; Potter, Crystal; Brombacher, Frank; Aronow, Bruce; Wills-Karp, Marsha; Finkelman, Fred D (2011. ) Selective stimulation of IL-4 receptor on smooth muscle induces airway hyperresponsiveness in mice.The Journal of experimental medicine, , 208 (4 ) ,853-67 More Information

Strait, Richard T; Mahler, Ashley; Hogan, Simon; Khodoun, Marat; Shibuya, Akira; Finkelman, Fred D (2011. ) Ingested allergens must be absorbed systemically to induce systemic anaphylaxis.The Journal of allergy and clinical immunology, , 127 (4 ) ,982-9.e1 More Information

Zhu, Hongyan; Perkins, Charles; Mingler, Melissa K; Finkelman, Fred D; Rothenberg, Marc E (2011. ) The role of neuropeptide S and neuropeptide S receptor 1 in regulation of respiratory function in mice.Peptides, , 32 (4 ) ,818-25 More Information

Finkelman, Fred D (2010. ) Peanut allergy and anaphylaxis.Current opinion in immunology, , 22 (6 ) ,783-8 More Information

Tripathi, Pulak; Kurtulus, Sema; Wojciechowski, Sara; Sholl, Allyson; Hoebe, Kasper; Morris, Suzanne C; Finkelman, Fred D; Grimes, H Leighton; Hildeman, David A (2010. ) STAT5 is critical to maintain effector CD8+ T cell responses.Journal of immunology (Baltimore, Md. : 1950), , 185 (4 ) ,2116-24 More Information

Zuo, Li; Fulkerson, Patricia C; Finkelman, Fred D; Mingler, Melissa; Fischetti, Christine A; Blanchard, Carine; Rothenberg, Marc E (2010. ) IL-13 induces esophageal remodeling and gene expression by an eosinophil-independent, IL-13R alpha 2-inhibited pathway.Journal of immunology (Baltimore, Md. : 1950), , 185 (1 ) ,660-9 More Information

Herbert, De'Broski R; Orekov, Tatyana; Roloson, Amanda; Ilies, Monica; Perkins, Charles; O'Brien, William; Cederbaum, Stephen; Christianson, David W; Zimmermann, Nives; Rothenberg, Marc E; Finkelman, Fred D (2010. ) Arginase I suppresses IL-12/IL-23p40-driven intestinal inflammation during acute schistosomiasis.Journal of immunology (Baltimore, Md. : 1950), , 184 (11 ) ,6438-46 More Information

Steinbrecher, Kris A; Horowitz, Netanel A; Blevins, Elizabeth A; Barney, Kelley A; Shaw, Maureen A; Harmel-Laws, Eleana; Finkelman, Fred D; Flick, Matthew J; Pinkerton, Malinda D; Talmage, Kathryn E; Kombrinck, Keith W; Witte, David P; Palumbo, Joseph S (2010. ) Colitis-associated cancer is dependent on the interplay between the hemostatic and inflammatory systems and supported by integrin alpha(M)beta(2) engagement of fibrinogen.Cancer research, , 70 (7 ) ,2634-43 More Information

Finkelman, Fred D; Hogan, Simon P; Hershey, Gurjit K Khurana; Rothenberg, Marc E; Wills-Karp, Marsha (2010. ) Importance of cytokines in murine allergic airway disease and human asthma.Journal of immunology (Baltimore, Md. : 1950), , 184 (4 ) ,1663-74 More Information

Osterfeld, Heather; Ahrens, Richard; Strait, Richard; Finkelman, Fred D; Renauld, Jean-Christophe; Hogan, Simon P (2010. ) Differential roles for the IL-9/IL-9 receptor alpha-chain pathway in systemic and oral antigen-induced anaphylaxis.The Journal of allergy and clinical immunology, , 125 (2 ) ,469-476.e2 More Information

Finkelman, Fred D; Boyce, Joshua A; Vercelli, Donata; Rothenberg, Marc E (2010. ) Key advances in mechanisms of asthma, allergy, and immunology in 2009.The Journal of allergy and clinical immunology, , 125 (2 ) ,312-8 More Information

Groschwitz, Katherine R; Ahrens, Richard; Osterfeld, Heather; Gurish, Michael F; Han, Xiaonan; Abrink, Magnus; Finkelman, Fred D; Pejler, Gunnar; Hogan, Simon P (2009. ) Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism.Proceedings of the National Academy of Sciences of the United States of America, , 106 (52 ) ,22381-6 More Information

Herbert, De'Broski R; Yang, Jun-Qi; Hogan, Simon P; Groschwitz, Kathryn; Khodoun, Marat; Munitz, Ariel; Orekov, Tatyana; Perkins, Charles; Wang, Quan; Brombacher, Frank; Urban, Joseph F; Rothenberg, Marc E; Finkelman, Fred D (2009. ) Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infection.The Journal of experimental medicine, , 206 (13 ) ,2947-57 More Information

Chen, Weiguo; Sivaprasad, Umasundari; Tabata, Yasuhiro; Gibson, Aaron M; Stier, Matthew T; Finkelman, Fred D; Hershey, Gurjit K Khurana (2009. ) IL-13R alpha 2 membrane and soluble isoforms differ in humans and mice.Journal of immunology (Baltimore, Md. : 1950), , 183 (12 ) ,7870-6 More Information

Madan, Rajat; Demircik, Filiz; Surianarayanan, Sangeetha; Allen, Jessica L; Divanovic, Senad; Trompette, Aurelien; Yogev, Nir; Gu, Yuanyuan; Khodoun, Marat; Hildeman, David; Boespflug, Nicholas; Fogolin, Mariela B; Gröbe, Lothar; Greweling, Marina; Finkelman, Fred D; Cardin, Rhonda; Mohrs, Markus; Müller, Werner; Waisman, Ari; Roers, Axel; Karp, Christopher L (2009. ) Nonredundant roles for B cell-derived IL-10 in immune counter-regulation.Journal of immunology (Baltimore, Md. : 1950), , 183 (4 ) ,2312-20 More Information

Lewis, Christina C; Aronow, Bruce; Hutton, John; Santeliz, Joanna; Dienger, Krista; Herman, Nancy; Finkelman, Fred D; Wills-Karp, Marsha (2009. ) Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lung.The Journal of allergy and clinical immunology, , 123 (4 ) ,795-804.e8 More Information

Khodoun, Marat; Strait, Richard; Orekov, Tatyana; Hogan, Simon; Karasuyama, Hajime; Herbert, De'broski R; Köhl, Jörg; Finkelman, Fred D (2009. ) Peanuts can contribute to anaphylactic shock by activating complement.The Journal of allergy and clinical immunology, , 123 (2 ) ,342-51 More Information

Morris, Suzanne C; Heidorn, Stephanie M; Herbert, De'Broski R; Perkins, Charles; Hildeman, David A; Khodoun, Marat V; Finkelman, Fred D (2009. ) Endogenously produced IL-4 nonredundantly stimulates CD8+ T cell proliferation.Journal of immunology (Baltimore, Md. : 1950), , 182 (3 ) ,1429-38 More Information

Brandt, Eric B; Munitz, Ariel; Orekov, Tatyana; Mingler, Melissa K; McBride, Melissa; Finkelman, Fred D; Rothenberg, Marc E (2009. ) Targeting IL-4/IL-13 signaling to alleviate oral allergen-induced diarrhea.The Journal of allergy and clinical immunology, , 123 (1 ) ,53-8 More Information

Wills-Karp, Marsha; Finkelman, Fred D (2008. ) Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.Science signaling, , 1 (51 ) ,pe55 More Information

Herbert, De'Broski R; Orekov, Tatyana; Perkins, Charles; Finkelman, Fred D (2008. ) IL-10 and TGF-beta redundantly protect against severe liver injury and mortality during acute schistosomiasis.Journal of immunology (Baltimore, Md. : 1950), , 181 (10 ) ,7214-20 More Information

Yamada, Yoshiyuki; Sanchez-Aguilera, Abel; Brandt, Eric B; McBride, Melissa; Al-Moamen, Nabeel J H; Finkelman, Fred D; Williams, David A; Cancelas, Jose A; Rothenberg, Marc E (2008. ) FIP1L1/PDGFRalpha synergizes with SCF to induce systemic mastocytosis in a murine model of chronic eosinophilic leukemia/hypereosinophilic syndrome.Blood, , 112 (6 ) ,2500-7 More Information

Munitz, A; Brandt, E B; Mingler, M; Finkelman, F D; Rothenberg, M E (2008. ) Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis.Proceedings of the National Academy of Sciences of the United States of America, , 105 (20 ) ,7240-5 More Information

Forbes, Elizabeth E; Groschwitz, Katherine; Abonia, J Pablo; Brandt, Eric B; Cohen, Elizabeth; Blanchard, Carine; Ahrens, Richard; Seidu, Luqman; McKenzie, Andrew; Strait, Richard; Finkelman, Fred D; Foster, Paul S; Matthaei, Klaus I; Rothenberg, Marc E; Hogan, Simon P (2008. ) IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity.The Journal of experimental medicine, , 205 (4 ) ,897-913 More Information

Herbert, De'Broski R; Orekov, Tatyana; Perkins, Charles; Rothenberg, Marc E; Finkelman, Fred D (2008. ) IL-4R alpha expression by bone marrow-derived cells is necessary and sufficient for host protection against acute schistosomiasis.Journal of immunology (Baltimore, Md. : 1950), , 180 (7 ) ,4948-55 More Information

Phelan, James D; Orekov, Tatyana; Finkelman, Fred D (2008. ) Cutting edge: mechanism of enhancement of in vivo cytokine effects by anti-cytokine monoclonal antibodies.Journal of immunology (Baltimore, Md. : 1950), , 180 (1 ) ,44-8 More Information

Khodoun, Marat; Lewis, Christina C; Lewis, Christina; Yang, Jun-Qi; Orekov, Tatyana; Potter, Crystal; Wynn, Thomas; Mentink-Kane, Margaret; Hershey, Gurjit K Khurana; Wills-Karp, Marsha; Finkelman, Fred D (2007. ) Differences in expression, affinity, and function of soluble (s)IL-4Ralpha and sIL-13Ralpha2 suggest opposite effects on allergic responses.Journal of immunology (Baltimore, Md. : 1950), , 179 (10 ) ,6429-38 More Information

Finkelman, Fred D (2007. ) Anaphylaxis: lessons from mouse models.The Journal of allergy and clinical immunology, , 120 (3 ) ,506-15; quiz 516-7 More Information

Finkelman, Fred D; Vercelli, Donata (2007. ) Advances in asthma, allergy mechanisms, and genetics in 2006.The Journal of allergy and clinical immunology, , 120 (3 ) ,544-50 More Information

Wojciechowski, Sara; Tripathi, Pulak; Bourdeau, Tristan; Acero, Luis; Grimes, H Leighton; Katz, Jonathan D; Finkelman, Fred D; Hildeman, David A (2007. ) Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis.The Journal of experimental medicine, , 204 (7 ) ,1665-75 More Information

Tripathi, Pulak; Mitchell, Thomas C; Finkelman, Fred; Hildeman, David A (2007. ) Cutting Edge: Limiting amounts of IL-7 do not control contraction of CD4+ T cell responses.Journal of immunology (Baltimore, Md. : 1950), , 178 (7 ) ,4027-31 More Information

Rothenberg, Marc E; Doepker, Matthew P; Lewkowich, Ian P; Chiaramonte, Monica G; Stringer, Keith F; Finkelman, Fred D; MacLeod, Carol L; Ellies, Lesley G; Zimmermann, Nives (2006. ) Cationic amino acid transporter 2 regulates inflammatory homeostasis in the lung.Proceedings of the National Academy of Sciences of the United States of America, , 103 (40 ) ,14895-900 More Information

Perkins, Charles; Wills-Karp, Marsha; Finkelman, Fred D (2006. ) IL-4 induces IL-13-independent allergic airway inflammation.The Journal of allergy and clinical immunology, , 118 (2 ) ,410-9 More Information

Akei, Hiroko Saito; Brandt, Eric B; Mishra, Anil; Strait, Richard T; Finkelman, Fred D; Warrier, Manoj R; Hershey, Gurjit K Khurana; Blanchard, Carine; Rothenberg, Marc E (2006. ) Epicutaneous aeroallergen exposure induces systemic TH2 immunity that predisposes to allergic nasal responses.The Journal of allergy and clinical immunology, , 118 (1 ) ,62-9 More Information

Morris, Suzanne C; Orekhova, Tatyana; Meadows, Michelle J; Heidorn, Stephanie M; Yang, Junqi; Finkelman, Fred D (2006. ) IL-4 induces in vivo production of IFN-gamma by NK and NKT cells.Journal of immunology (Baltimore, Md. : 1950), , 176 (9 ) ,5299-305 More Information

Strait, Richard T; Morris, Suzanne C; Finkelman, Fred D (2006. ) IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and Fc gamma RIIb cross-linking.The Journal of clinical investigation, , 116 (3 ) ,833-41 More Information

Zimmermann, Nives; Doepker, Matthew P; Witte, David P; Stringer, Keith F; Fulkerson, Patricia C; Pope, Samuel M; Brandt, Eric B; Mishra, Anil; King, Nina E; Nikolaidis, Nikolaos M; Wills-Karp, Marsha; Finkelman, Fred D; Rothenberg, Marc E (2005. ) Expression and regulation of small proline-rich protein 2 in allergic inflammation.American journal of respiratory cell and molecular biology, , 32 (5 ) ,428-35 More Information

Finkelman, Fred D; Yang, Mingyan; Perkins, Charles; Schleifer, Kathleen; Sproles, Alyssa; Santeliz, Joanna; Bernstein, Jonathan A; Rothenberg, Marc E; Morris, Suzanne C; Wills-Karp, Marsha (2005. ) Suppressive effect of IL-4 on IL-13-induced genes in mouse lung.Journal of immunology (Baltimore, Md. : 1950), , 174 (8 ) ,4630-8 More Information

Finkelman, Fred D; Rothenberg, Marc E; Brandt, Eric B; Morris, Suzanne C; Strait, Richard T (2005. ) Molecular mechanisms of anaphylaxis: lessons from studies with murine models.The Journal of allergy and clinical immunology, , 115 (3 ) ,449-57; quiz 458 More Information

Sussman, Jeffrey J; Parihar, Robin; Winstead, Karen; Finkelman, Fred D (2004. ) Prolonged culture of vaccine-primed lymphocytes results in decreased antitumor killing and change in cytokine secretion.Cancer research, , 64 (24 ) ,9124-30 More Information

Fulkerson, Patricia C; Zimmermann, Nives; Hassman, Lynn M; Finkelman, Fred D; Rothenberg, Marc E (2004. ) Pulmonary chemokine expression is coordinately regulated by STAT1, STAT6, and IFN-gamma.Journal of immunology (Baltimore, Md. : 1950), , 173 (12 ) ,7565-74 More Information

Khodoun, Marat V; Orekhova, Tatyana; Potter, Crystal; Morris, Suzanne; Finkelman, Fred D (2004. ) Basophils initiate IL-4 production during a memory T-dependent response.The Journal of experimental medicine, , 200 (7 ) ,857-70 More Information

Finkelman, Fred D; Shea-Donohue, Terez; Morris, Suzanne C; Gildea, Lucy; Strait, Richard; Madden, Kathleen B; Schopf, Lisa; Urban, Joseph F (2004. ) Interleukin-4- and interleukin-13-mediated host protection against intestinal nematode parasites.Immunological reviews, , 201 ,139-55 More Information

Finkelman, Fred D; Yang, Mingyan; Orekhova, Tatyana; Clyne, Erin; Bernstein, Jonathan; Whitekus, Michael; Diaz-Sanchez, David; Morris, Suzanne C (2004. ) Diesel exhaust particles suppress in vivo IFN-gamma production by inhibiting cytokine effects on NK and NKT cells.Journal of immunology (Baltimore, Md. : 1950), , 172 (6 ) ,3808-13 More Information

Han, Shuhua; Zhang, Xuejun; Xu, Renling; Finkelman, Fred D; Brombacher, Frank; Zheng, Biao (2004. ) IgD+IgM- B cells mount immune responses that exhibit altered antibody repertoire.European journal of immunology, , 34 (3 ) ,661-668 More Information

Wan, Huajing; Kaestner, Klaus H; Ang, Siew-Lan; Ikegami, Machiko; Finkelman, Fred D; Stahlman, Mildred T; Fulkerson, Patricia C; Rothenberg, Marc E; Whitsett, Jeffrey A (2004. ) Foxa2 regulates alveolarization and goblet cell hyperplasia.Development (Cambridge, England), , 131 (4 ) ,953-64 More Information

Strait, Richard; Morrist, Suzanne C; Finkelman, Fred D (2004. ) Cytokine enhancement of anaphylaxis. Novartis Foundation symposium, , 257 ,80-91; discussion 91

Brandt, Eric B; Strait, Richard T; Hershko, Dan; Wang, Quan; Muntel, Emily E; Scribner, Troy A; Zimmermann, Nives; Finkelman, Fred D; Rothenberg, Marc E (2003. ) Mast cells are required for experimental oral allergen-induced diarrhea.The Journal of clinical investigation, , 112 (11 ) ,1666-77 More Information

Nikolaidis, Nikolaos M; Zimmermann, Nives; King, Nina E; Mishra, Anil; Pope, Samuel M; Finkelman, Fred D; Rothenberg, Marc E (2003. ) Trefoil factor-2 is an allergen-induced gene regulated by Th2 cytokines and STAT6 in the lung.American journal of respiratory cell and molecular biology, , 29 (4 ) ,458-64 More Information

Finkelman, Fred; Morris, Suzanne; Orekhova, Tatyana; Sehy, David (2003. ) The in vivo cytokine capture assay for measurement of cytokine production in the mouse.Current protocols in immunology, , Chapter 6 ,Unit 6.28 More Information

Gildea, Lucy A; Gibbons, Reta; Finkelman, Fred D; Deepe, George S (2003. ) Overexpression of interleukin-4 in lungs of mice impairs elimination of Histoplasma capsulatum.Infection and immunity, , 71 (7 ) ,3787-93 More Information

Singh, Ram Raj; Saxena, Vijay; Zang, Song; Li, Lily; Finkelman, Fred D; Witte, David P; Jacob, Chaim O (2003. ) Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis.Journal of immunology (Baltimore, Md. : 1950), , 170 (9 ) ,4818-25 More Information

Strait, Richard T; Morris, Suzanne C; Smiley, Kristi; Urban, Joseph F; Finkelman, Fred D (2003. ) IL-4 exacerbates anaphylaxis.Journal of immunology (Baltimore, Md. : 1950), , 170 (7 ) ,3835-42 More Information

Woo, Alison L; Gildea, Lucy A; Tack, Leslie M; Miller, Marian L; Spicer, Zachary; Millhorn, David E; Finkelman, Fred D; Hassett, Daniel J; Shull, Gary E (2002. ) In vivo evidence for interferon-gamma-mediated homeostatic mechanisms in small intestine of the NHE3 Na+/H+ exchanger knockout model of congenital diarrhea.The Journal of biological chemistry, , 277 (50 ) ,49036-46 More Information

Morris, Suzanne C; Dragula, Nanette L; Finkelman, Fred D (2002. ) IL-4 promotes Stat6-dependent survival of autoreactive B cells in vivo without inducing autoantibody production.Journal of immunology (Baltimore, Md. : 1950), , 169 (4 ) ,1696-704 More Information

Singh, Ram Raj; Ebling, Fanny M; Albuquerque, D Alves; Saxena, Vijay; Kumar, Vipin; Giannini, Edward H; Marion, Tony N; Finkelman, Fred D; Hahn, Bevra H (2002. ) Induction of autoantibody production is limited in nonautoimmune mice.Journal of immunology (Baltimore, Md. : 1950), , 169 (1 ) ,587-94 More Information

Strait, Richard T; Morris, Suzanne C; Yang, Mingyan; Qu, Xiao-Wu; Finkelman, Fred D (2002. ) Pathways of anaphylaxis in the mouse.The Journal of allergy and clinical immunology, , 109 (4 ) ,658-68 More Information

Thornton, S; Kuhn, K A; Finkelman, F D; Hirsch, R (2001. ) NK cells secrete high levels of IFN-gamma in response to in vivo administration of IL-2.European journal of immunology, , 31 (11 ) ,3355-60 More Information

Finkelman, F D; Urban, J F (2001. ) The other side of the coin: the protective role of the TH2 cytokines.The Journal of allergy and clinical immunology, , 107 (5 ) ,772-80 More Information

Zimmermann, N; Hogan, S P; Mishra, A; Brandt, E B; Bodette, T R; Pope, S M; Finkelman, F D; Rothenberg, M E (2000. ) Murine eotaxin-2: a constitutive eosinophil chemokine induced by allergen challenge and IL-4 overexpression.Journal of immunology (Baltimore, Md. : 1950), , 165 (10 ) ,5839-46 More Information

Thornton, S; Boivin, G P; Kim, K N; Finkelman, F D; Hirsch, R (2000. ) Heterogeneous effects of IL-2 on collagen-induced arthritis.Journal of immunology (Baltimore, Md. : 1950), , 165 (3 ) ,1557-63 More Information

Mori, M; Morris, S C; Orekhova, T; Marinaro, M; Giannini, E; Finkelman, F D (2000. ) IL-4 promotes the migration of circulating B cells to the spleen and increases splenic B cell survival.Journal of immunology (Baltimore, Md. : 1950), , 164 (11 ) ,5704-12 More Information

Morris, S C; Moroldo, M; Giannini, E H; Orekhova, T; Finkelman, F D (2000. ) In vivo survival of autoreactive B cells: characterization of long-lived B cells.Journal of immunology (Baltimore, Md. : 1950), , 164 (6 ) ,3035-46 More Information

Finkelman, F D; Morris, S C; Orekhova, T; Mori, M; Donaldson, D; Reiner, S L; Reilly, N L; Schopf, L; Urban, J F (2000. ) Stat6 regulation of in vivo IL-4 responses.Journal of immunology (Baltimore, Md. : 1950), , 164 (5 ) ,2303-10 More Information

Morris, S C; Gause, W C; Finkelman, F D (2000. ) IL-4 suppression of in vivo T cell activation and antibody production.Journal of immunology (Baltimore, Md. : 1950), , 164 (4 ) ,1734-40 More Information

Finkelman, F D; Morris, S C (1999. ) Development of an assay to measure in vivo cytokine production in the mouse.International immunology, , 11 (11 ) ,1811-8 More Information

Mendenhall, C L; Finkelman, F; Means, R T; Sherman, K E; Nguyen, V T; Grossman, C E; Morris, S C; Rouster, S; Roselle, G A (1999. ) Cytokine response to BCG infection in alcohol-fed mice.Alcohol (Fayetteville, N.Y.), , 19 (1 ) ,57-63 More Information

Finkelman, F D; Wynn, T A; Donaldson, D D; Urban, J F (1999. ) The role of IL-13 in helminth-induced inflammation and protective immunity against nematode infections.Current opinion in immunology, , 11 (4 ) ,420-6 More Information

Morris, S C; Coffman, R L; Finkelman, F D (1998. ) In vivo IL-4 responses to anti-IgD antibody are MHC class II dependent and beta 2-microglobulin independent and develop normally in the absence of IL-4 priming of T cells. Journal of immunology (Baltimore, Md. : 1950), , 160 (7 ) ,3299-304

Finkelman, F D; Shea-Donohue, T; Goldhill, J; Sullivan, C A; Morris, S C; Madden, K B; Gause, W C; Urban, J F (1997. ) Cytokine regulation of host defense against parasitic gastrointestinal nematodes: lessons from studies with rodent models.Annual review of immunology, , 15 ,505-33 More Information

Finkelman, F D; Lees, A; Birnbaum, R; Gause, W C; Morris, S C (1996. ) Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion. Journal of immunology (Baltimore, Md. : 1950), , 157 (4 ) ,1406-14

Huang H.;Li Y.;Liang J.;Finkelman F. (06-20-2018. ) Molecular regulation of histamine synthesis.Frontiers in Immunology, , 9 (JUN ) , More Information

Finkelman F.;Mond J.;Metcalf E. (01-01-2018. ) Antiimmunoglobulin antibody induction of B lymphocyte activation and differentiation in vivo and in .B-Lymphocyte Differentiation, , 41-59 More Information

Strait R.;Posgai M.;Mahler A.;Barasa N.;Jacob C.;Köhl J.;Ehlers M.;Stringer K.;Shanmukhappa S.;Witte D.;Hossain M.;Khodoun M.;Herr A.;Finkelman F. (10-29-2015. ) Erratum: IgG1 protects against renal disease in a mouse model of cryoglobulinaemia (Nature (2015) 51.Nature, , 526 (7575 ) ,728 More Information

Fernandez C.;Stewart E.;Panetta J.;Wilkinson M.;Morrison A.;Finkelman F.;Sandlund J.;Pui C.;Jeha S.;Relling M.;Campbell P. (01-01-2014. ) Successful challenges using native E. coli asparaginase after hypersensitivity reactions to PEGylate.Cancer Chemotherapy and Pharmacology, , 73 (6 ) ,1307-1313 More Information

Bochner B.;Rothenberg M.;Boyce J.;Finkelman F. (03-01-2013. ) Advances in mechanisms of allergy and clinical immunology in 2012.Journal of Allergy and Clinical Immunology, , 131 (3 ) ,661-667 More Information

Li J.;Wang Y.;Tang L.;De Villiers W.;Cohen D.;Woodward J.;Finkelman F.;Eckhardt E. (02-01-2013. ) Dietary medium-chain triglycerides promote oral allergic sensitization and orally induced anaphylaxi.Journal of Allergy and Clinical Immunology, , 131 (2 ) ,442-450 More Information

Finkelman F. (01-01-2013. ) On sharing unique reagents.Journal of Allergy and Clinical Immunology, , 132 (1 ) ,245-246 More Information

Khodoun M.V.;Kucuk Z.Y.;Strait R.T.;Krishnamurthy D.;Janek K.;Clay C.D.;Morris S.C.;Finkelman F.D. (01-01-2013. ) Rapid desensitization of mice with anti-Fc?RIIb/Fc?RIII mAb safely prevents IgG-mediated anaphylaxis.Journal of Allergy and Clinical Immunology, , 132 (6 ) ,1375-1387 More Information

Khodoun M.V.;Kucuk Z.Y.;Strait R.T.;Krishnamurthy D.;Janek K.;Lewkowich I.;Morris S.C.;Finkelman F.D. (01-01-2013. ) Rapid polyclonal desensitization with antibodies to IgE and Fc?RI?.Journal of Allergy and Clinical Immunology, , 131 (6 ) , More Information

Chen W.;Sivaprasad U.;Gibson A.;Ericksen M.;Cunningham C.;Bass S.;Kinker K.;Finkelman F.;Wills-Karp M.;Khurana Hershey G. (01-01-2013. ) IL-13 receptor ?2 contributes to development of experimental allergic asthma.Journal of Allergy and Clinical Immunology, , 132 (4 ) , More Information

Shao W.;Zhen Y.;Finkelman F.;Eisenberg R.;Cohen P. (12-01-2012. ) Intrinsic unresponsiveness of Mertk-/- B cells to chronic graft-versus-host d.Journal of Autoimmunity, , 39 (4 ) ,412-419 More Information

Finkelman F. (10-01-2012. ) Worming their way into the pharmacy: Use of worms and worm products to treat inflammatory diseases.Arthritis and Rheumatism, , 64 (10 ) ,3068-3071 More Information

Huber A.;Finkelman F.;Li C.;Concepcion E.;Smith E.;Jacobson E.;Latif R.;Keddache M.;Zhang W.;Tomer Y. (09-15-2012. ) Genetically driven target tissue overexpression of CD40: A novel mechanism in autoimmune disease.Journal of Immunology, , 189 (6 ) ,3043-3053 More Information

Karsten C.M.;Pandey M.K.;Figge J.;Kilchenstein R.;Taylor P.R.;Rosas M.;McDonald J.U.;Orr S.J.;Berger M.;Petzold D.;Blanchard V.;Winkler A.;Hess C.;Reid D.M.;Majoul I.V.;Strait R.T.;Harris N.L.;Köhl G.;Wex E.;Ludwig R.;Zillikens D.;Nimmerjahn F.;Finkelman F.D.;Brown G.D.;Ehlers M.;Köhl J. (09-01-2012. ) Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of Fc?RIIB and dec.Nature Medicine, , 18 (9 ) ,1401-1406 More Information

Falanga Y.T.;Chaimowitz N.S.;Charles N.;Finkelman F.D.;Pullen N.A.;Barbour S.;Dholaria K.;Faber T.;Kolawole M.;Huang B.;Odom S.;Rivera J.;Carlyon J.;Conrad D.H.;Spiegel S.;Oskeritzian C.A.;Ryan J.J. (05-01-2012. ) Lyn but not Fyn kinase controls IgG-mediated systemic anaphylaxis.Journal of Immunology, , 188 (9 ) ,4360-4368 More Information

Artis D.;Maizels R.;Finkelman F. (04-26-2012. ) Forum: Immunology: Allergy challenged.Nature, , 484 (7395 ) ,458-459 More Information

Boyce J.;Bochner B.;Finkelman F.;Rothenberg M. (01-01-2012. ) Advances in mechanisms of asthma, allergy, and immunology in 2011.Journal of Allergy and Clinical Immunology, , 129 (2 ) ,335-341 More Information

Finkelman F. (12-01-2011. ) IgE-dependent and independent effector mechanisms in human and murine anaphylaxis.Anaphylaxis and Hypersensitivity Reactions, , 127-144 More Information

Wills-Karp M.;Finkelman F. (11-01-2011. ) Innate lymphoid cells wield a double-edged sword.Nature Immunology, , 12 (11 ) ,1025-1027 More Information

Jenkins S.;Ruckerl D.;Cook P.;Jones L.;Finkelman F.;Van Rooijen N.;MacDonald A.;Allen J. (06-10-2011. ) Local macrophage proliferation, rather than recruitment from the blood, is a signature of T .Science, , 332 (6035 ) ,1284-1288 More Information

Foster A.;Soloviova K.;Puliaeva I.;Puliaiev M.;Puliaev R.;Finkelman F.;Via C. (06-01-2011. ) Donor CD8 T cells and IFN-? are critical for sex-based differences in donor CD4 T cell engraftment a.Journal of Immunology, , 186 (11 ) ,6238-6254 More Information

Broide D.;Finkelman F.;Bochner B.;Rothenberg M. (03-01-2011. ) Advances in mechanisms of asthma, allergy, and immunology in 2010.Journal of Allergy and Clinical Immunology, , 127 (3 ) ,689-695 More Information

Arumugam M.;Ahrens R.;Osterfeld H.;Kottyan L.;Shang X.;Maclennan J.;Zimmermann N.;Zheng Y.;Finkelman F.;Hogan S. (02-03-2011. ) Increased susceptibility of 129SvEvBrd mice to IgE-Mast cell mediated anaphylaxis.BMC Immunology, , 12 , More Information

Strait R.;Mahler A.;Hogan S.;Khodoun M.;Shibuya A.;Finkelman F. (01-01-2011. ) Ingested allergens must be absorbed systemically to induce systemic anaphylaxis.Journal of Allergy and Clinical Immunology, , 127 (4 ) , More Information

Milner J.;Orekov T.;Ward J.;Cheng L.;Torres-Velez F.;Junttila I.;Sun G.;Buller M.;Morris S.;Finkelman F.;Paul W. (10-07-2010. ) Sustained IL-4 exposure leads to a novel pathway for hemophagocytosis, inflammation, and tissue macr.Blood, , 116 (14 ) ,2476-2483 More Information

McCoy M.;Finkelman F.;Straus D. (09-15-2010. ) Th2-specific immunity and function of peripheral T cells is regulated by the p56Lck Src homology 3 d.Journal of Immunology, , 185 (6 ) ,3285-3294 More Information

Jones T.;Finkelman F.;Austen K.;Gurish M. (08-01-2010. ) T regulatory cells control antigen-induced recruitment of mast cell progenitors to the lungs of C57B.Journal of Immunology, , 185 (3 ) ,1804-1811 More Information

Morales-Tirado V.;Sojka D.;Katzman S.;Lazarski C.;Finkelman F.;Urban J.;Fowell D. (04-29-2010. ) Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function.Blood, , 115 (17 ) ,3498-3507 More Information

Osterfeld H.;Ahrens R.;Strait R.;Finkelman F.;Renauld J.;Hogan S. (01-01-2010. ) Differential roles for the IL-9/IL-9 receptor ?-chain pathway in systemic and oral antigen-induced a.Journal of Allergy and Clinical Immunology, , 125 (2 ) , More Information

Finkelman F. (11-01-2009. ) Basophils as TH 2-inducing APCs: The dog can sing but is it a diva.Immunology and Cell Biology, , 87 (8 ) ,568-570 More Information

Jones T.;Hallgren J.;Humbles A.;Burwell T.;Finkelman F.;Alcaide P.;Austen K.;Gurish M. (10-15-2009. ) Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restrict.Journal of Immunology, , 183 (8 ) ,5251-5260 More Information

Simons F.E.R.;Frew A.J.;Ansotegui I.J.;Bochner B.S.;Golden D.B.K.;Finkelman F.D.;Leung D.Y.M.;Lotvall J.;Marone G.;Metcalfe D.D.;M-ller U.;Rosenwasser L.J.;Sampson H.A.;Schwartz L.B.;Van Hage M.;Walls A.F. (03-01-2009. ) Practical allergy (PRACTALL) report: Risk assessment in anaphylaxis .Alergia Astma Immunologia, , 14 (1 ) ,14-16

Le Gros G.;Ben-Sasson S.;Seder R.;Finkelman F.;Paul W. (09-01-2008. ) Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required .Journal of immunology (Baltimore, Md. : 1950), , 181 (5 ) ,2943-2951

Finkelman F.;Wills-Karp M. (03-01-2008. ) Usefulness and optimization of mouse models of allergic airway disease.Journal of Allergy and Clinical Immunology, , 121 (3 ) ,603-606 More Information

Finkelman F. (02-01-2008. ) Use of unrestrained, single-chamber barometric plethysmography to evaluate sensitivity to cholinergi.Journal of Allergy and Clinical Immunology, , 121 (2 ) ,334-335 More Information

Simons F.;Frew A.;Ansotegui I.;Bochner B.;Golden D.;Finkelman F. (02-01-2008. ) Practical allergy (PRACTALL) report: Risk assessment in anaphylaxis (Allergy: European Journal of Al.Allergy: European Journal of Allergy and Clinical Immunology, , 63 (2 ) ,250 More Information

Khodoun M.;Lewis C.;Yang J.;Orekov T.;Potter C.;Wynn T.;Mentink-Kane M.;Khurana Hershey G.;Wills-Karp M.;Finkelman F. (01-01-2008. ) Differences in expression, affinity, and function of soluble (s)IL-4R? and sIL-13R?2 suggest opposit .Journal of Immunology, , 180 (1 ) ,664

Simons F.E.R.;Frew A.J.;Ansotegui I.J.;Bochner B.S.;Golden D.B.K.;Finkelman F.D.;Leung D.Y.M.;Lotvall J.;Marone G.;Metcalfe D.D.;Müller U.;Rosenwasser L.J.;Sampson H.A.;Schwartz L.B.;Van Hage M.;Walls A.F. (01-01-2008. ) Practical allergy (PRACTALL) report: Risk assessment in anaphylaxis.Allergy: European Journal of Allergy and Clinical Immunology, , 63 (1 ) ,35-37 More Information

Horsnell W.G.C.;Cutler A.J.;Hoving J.C.;Mearns H.;Myburgh E.;Arendse B.;Finkelman F.D.;Owens G.K.;Erle D.;Brombacher F. (09-01-2007. ) Erratum: Delayed goblet cell hyperplasia, acetylcholine receptor expression, and worm expulsion in S.PLoS Pathogens, , 3 (4 ) ,566 More Information

Simons F.E.R.;Frew A.J.;Ansotegui I.J.;Bochner B.S.;Golden D.B.K.;Finkelman F.D.;Leung D.Y.M.;Lotvall J.;Marone G.;Metcalfe D.D.;Müller U.;Rosenwasser L.J.;Sampson H.A.;Schwartz L.B.;van Hage M.;Walls A.F. (07-01-2007. ) Risk assessment in anaphylaxis: Current and future approaches.Journal of Allergy and Clinical Immunology, , 120 (1 SUPPL. ) , More Information

Munitz A.;Bachelet I.;Finkelman F.;Rothenberg M.;Levi-Schaffer F. (05-01-2007. ) CD48 Is critically involved in allergic eosinophilic airway inflammation.American Journal of Respiratory and Critical Care Medicine, , 175 (9 ) ,911-918 More Information

Horsnell W.G.C.;Cutler A.J.;Hoving C.J.;Mearns H.;Myburgh E.;Arendse B.;Finkelman F.D.;Owens G.K.;Erle D.;Brombacher F. (01-01-2007. ) Delayed goblet cell hyperplasia, acetylcholine receptor expression, and worm expulsion in SMC-specif.PLoS Pathogens, , 3 (1 ) ,0046-0053 More Information

Munitz A.;Bachelet I.;Eliashar R.;Khodoun M.;Finkelman F.;Rothenberg M.;Levi-Schaffer F. (07-01-2006. ) CD48 is an allergen and IL-3-induced activation molecule on eosinophils.Journal of Immunology, , 177 (1 ) ,77-83 More Information

Chinen J.;Finkelman F.;Shearer W. (01-01-2006. ) Advances in basic and clinical immunology.Journal of Allergy and Clinical Immunology, , 118 (2 ) ,489-495 More Information

Zhao A.;Urban J.;Morimoto M.;Elfrey J.;Madden K.;Finkelman F.;Shea-Donohue T. (01-01-2006. ) Contribution of 5-HT2A Receptor in Nematode Infection-Induced Murine Intestin.Gastroenterology, , 131 (2 ) ,568-578 More Information

West E.;Lavoie T.;Orens J.;Chen E.;Ye S.;Finkelman F.;Garcia J.;McDyer J. (01-01-2006. ) Pluripotent allospecific CD8+ effector T cells traffic to lung in murine obli.American Journal of Respiratory Cell and Molecular Biology, , 34 (1 ) ,108-118 More Information

Morimoto M.;Morimoto M.;Zhao A.;Madden K.;Dawson H.;Finkelman F.;Mentink-Kane M.;Urban J.;Wynn T.;Shea-Donohue T. (01-01-2006. ) Functional importance of regional differences in localized gene expression of receptors for IL-13 in.Journal of Immunology, , 176 (1 ) ,491-495 More Information

Zhao A.;Morimoto M.;Dawson H.;Elfrey J.;Madden K.;Gause W.;Min B.;Finkelman F.;Urban J.;Shea-Donohue T. (08-15-2005. ) Immune regulation of protease-activated receptor-1 expression in murine small intestine during Nippo.Journal of Immunology, , 175 (4 ) ,2563-2569 More Information

Smith A.;Madden K.B.;Au Yeung K.J.;Zhao A.;Elfrey J.;Finkelman F.;Levander O.;Shea-Donohue T.;Urban J.F. (04-01-2005. ) Deficiencies in selenium and/or vitamin E lower the resistance of mice to Heligmosomoides polygyrus .Journal of Nutrition, , 135 (4 ) ,830-836

Lui Z.;Liu Q.;Hamed H.;Anthony R.M.;Foster A.;Finkelman F.D.;Urban J.F.;Gause W.C. (02-15-2005. ) IL-2 and autocrine IL-4 drive the in vivo development of antigen-specific Th2 T cells elicited by ne .Journal of Immunology, , 174 (4 ) ,2242-2249

Peng J.;Lin S.;Kung J.;Finkelman F.;Wu-Hsieh B. (02-01-2005. ) The combined effect of IL-4 and IL-10 suppresses the generation of, but does not change the polarity.International Immunology, , 17 (2 ) ,193-205 More Information

Finkelman F.;Galli S.;Golden D.;Lasser E.C.;Pedotti R.;Ring J.;Schwartz L.;Simons E.;Vercelli D. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,91-97

Kricek F.;Finkelman F.;Galli S.;Gould H.;Lasser E.C.;MacGlashan D.;Marone G.;Metzger H.;Sampson H. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,59-64

Kricek F.;Leung D.;MacGlashan D.;Marone G.;Lee T.H.;Vercelli D.;Mosbech H.;Schwartz L.;Sampson H.;Finkelman F. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,260-264

Galli S.;Gould H.;Marone G.;Schwartz L.;MacGlashan D.;Müller U.;Vercelli D.;Simons E.;Lee T.H.;Finkelman F.;Sampson H.;Ring J. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,37-44

Austen K.F.;Finkelman F.;Fisher M.;Galli S.;Golden D.;Müller U.;Ohtsu H.;Ring J.;Sampson H.;Schwartz L.;Simons E.;Vercelli D. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,74-79

Leung D.;Sampson H.;Simons E.;Golden D.;Pumphrey R.;Galli S.;Fisher M.;Muñoz-Furlong A.;Lee T.H.;Ring J.;Finkelman F.;Schwartz L.;Lasser E.C. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,171-176

Galli S.;Frank Austen K.;Finkelman F.;Fisher M.;Golden D.;Lasser E.C.;Mosbech H.;Müller U.;Pumphrey R.;Ring J.;Sampson H.;Schwartz L.;Simons E. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,128-132

Finkelman F.;Fisher M.;Galli S.;Gould H.;Golden D.;Lasser E.C.;Lee T.H.;Marone G.;Metzger H.;Müller U.;Pumphrey R.;Sampson H.;Schwartz L.;Vercelli D. (12-01-2004. ) Final discussion .Novartis Foundation Symposium, , 257 ,275-285

Galli S.;Ring J.;Müller U.;Sampson H.;Fisher M.;Marone G.;Schwartz L.;Austen K.F.;Lee T.H.;Simons E.;Pumphrey R.;Lasser E.C.;Ohtsu H.;Gould H.;Vercelli D.;Finkelman F. (12-01-2004. ) Discussion .Novartis Foundation Symposium, , 257 ,16-24

Zucker S.;Crabbe J.C.;Cooper IV G.;Finkelman F.;Largman C.;Mccarley R.W.;Rice L.;Rubin J.;Richardson B.;Seil F.;Snider G.L.;Vandenbark A.A. (10-01-2004. ) Veterans Administration support for medical research: Opinions of the endangered species of physicia.FASEB Journal, , 18 (13 ) ,1481-1486 More Information

Liu E.;Moriyama H.;Abiru N.;Paronen J.;Devendra D.;Finkelman F.;Eisenbarth G. (09-01-2004. ) Preventing peptide-induced anaphylaxis: Addition of C-terminal amino acids to produce a neutral isoe.Journal of Allergy and Clinical Immunology, , 114 (3 ) ,607-613 More Information

Min B.;Prout M.;Hu-Li J.;Zhu J.;Jankovic D.;Morgan E.;Urban J.;Dvorak A.;Finkelman F.;LeGros G.;Paul W. (08-16-2004. ) Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite.Journal of Experimental Medicine, , 200 (4 ) ,507-517 More Information

Puliaev R.;Nguyen P.;Finkelman F.D.;Via C.S. (07-15-2004. ) Differential requirement for IFN-? in CTL maturation in acute murine graft-versus-host disease.Journal of Immunology, , 173 (2 ) ,910-919 More Information

Liu Q.;Arseculeratne C.;Liu Z.;Whitmire J.;Grusby M.;Finkelman F.;Darling T.;Cheever A.;Swearengen J.;Urban J.;Gause W. (07-01-2004. ) Simultaneous deficiency in CD28 and STAT6 results in chronic ectoparasite-induced inflammatory skin .Infection and Immunity, , 72 (7 ) ,3706-3715 More Information

Madden K.;Yeung K.;Zhao A.;Gause W.;Finkelman F.;Katona I.;Urban J.;Shea-Donohue T. (05-01-2004. ) Enteric Nematodes Induce Stereotypic STAT6-Dependent Alterations in Intestinal Epithelial Cell Funct.Journal of Immunology, , 172 (9 ) ,5616-5621 More Information

Kelly-Welch A.;Wang H.;Wang L.;Pierce J.;Jay G.;Finkelman F.;Keegan A. (03-01-2004. ) Transgenic Expression of Insulin Receptor Substrate 2 in Murine B Cells Alters the Cell Density-Depe.Journal of Immunology, , 172 (5 ) ,2803-2810 More Information

Zhao A.;McDermott J.;Urban J.;Gause W.;Madden K.;Yeung K.;Morris S.;Finkelman F.;Shea-Donohue T. (07-15-2003. ) Dependence of IL-4, IL-13, and nematode-induced alterations in murine small intestinal smooth muscle.Journal of Immunology, , 171 (2 ) ,948-954 More Information

Madden K.;Whitman L.;Sullivan C.;Gause W.;Urban J.;Katona I.;Finkelman F.;Shea-Donohue T. (10-15-2002. ) Role of STAT6 and mast cells in IL-4- and IL-13-induced alterations in murine intestinal epithelial .Journal of Immunology, , 169 (8 ) ,4417-4422 More Information

Morris S.;Dragula N.;Finkelman F. (08-15-2002. ) IL-4 promotes Stat6-dependent survival of autoreactive B cells in vivo without inducing autoantibody.Journal of Immunology, , 169 (4 ) ,1696-1704 More Information

Singh R.R.;Ebling F.M.;Albuquerque D.A.;Saxena V.;Kumar V.;Giannini E.H.;Marion T.N.;Finkelman F.D.;Hahn B.H. (08-01-2002. ) Erratum: Induction of autoantibody production is limited in nonautoimmune mice (Journal of Immunolog .Journal of Immunology, , 169 (3 ) ,1647

Xu H.;Wipasa J.;Yan H.;Zeng M.;Makobongo M.O.;Finkelman F.D.;Kelso A.;Good M.F. (04-01-2002. ) The mechanism and significance of deletion of parasite-specific CD4+ T cells .Journal of Experimental Medicine, , 195 (7 ) ,881-892 More Information

Liu E.;Moriyama H.;Abiru N.;Miao D.;Yu L.;Taylor R.;Finkelman F.;Eisenbarth G. (01-01-2002. ) Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B.Journal of Clinical Investigation, , 110 (7 ) ,1021-1027 More Information

Seo S.;Fields M.;Buckler J.;Reed A.;Mandik-Nayak L.;Nish S.;Noelle R.;Turka L.;Finkelman F.;Caton A.;Erikson J. (01-01-2002. ) The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells.Immunity, , 16 (4 ) ,535-546 More Information

Via C.S.;Shustov A.;Rus V.;Lang T.;Nguyen P.;Finkelman F.D. (12-15-2001. ) In vivo neutralization of TNF-? promotes humoral autoimmunity by preventing the induction of CTL .Journal of Immunology, , 167 (12 ) ,6821-6826

Urban J.;Noben-Trauth N.;Schopf L.;Madden K.B.;Finkelman F.D. (12-01-2001. ) Cutting edge: IL-4 receptor expression by non-bone marrow-derived cells is required to expel gastroi .Journal of Immunology, , 167 (11 ) ,6078-6081

Shea-Donohue T.;Sullivan C.;Finkelman F.;Madden K.;Morris S.;Goldhill J.;Piñeiro-Carrero V.;Urban J. (08-15-2001. ) The role of IL-4 in Heligmosomoides polygyrus-induced alterations in murine intestinal epithelial ce.Journal of Immunology, , 167 (4 ) ,2234-2239 More Information

Peckham D.;Andersen-Nissen E.;Finkelman F.;Stunz L.;Ashman R. (01-01-2001. ) Difference in apoptosis induction between surface IgD and IgM.International Immunology, , 13 (3 ) ,285-295 More Information

Urban J.;Fang H.;Liu Q.;Ekkens M.J.;Chen S.J.;Nguyen D.;Mitro V.;Donaldson D.D.;Byrd C.;Peach R.;Morris S.C.;Finkelman F.D.;Schopf L.;Gause W.C. (04-15-2000. ) IL-13-mediated worm expulsion is B7 independent and IFN-? sensitive.Journal of Immunology, , 164 (8 ) ,4250-4256 More Information

Urban J.;Schopf L.;Morris S.;Orekhova T.;Madden K.;Betts C.;Gamble H.;Byrd C.;Donaldson D.;Else K.;Finkelman F. (02-15-2000. ) Stat6 signaling promotes protective immunity against Trichinella spiralis through a mast cell- and T.Journal of Immunology, , 164 (4 ) ,2046-2052 More Information

Hirunpetcharat C.;Finkelman F.;Clark I.A.;Good M.F. (06-14-1999. ) Malaria parasite-specific Th1-like T cells simultaneously reduce parasitemia and promote disease.Parasite Immunology, , 21 (6 ) ,319-329 More Information

Greenwald R.;Urban J.;Ekkens M.;Chen S.;Nguyen D.;Fang H.;Finkelman F.;Sharpe A.;Gause W. (04-01-1999. ) B7-2 is required for the progression but not the initiation of the type 2 immune response to a gastr .Journal of Immunology, , 162 (7 ) ,4133-4139

Artis D.;Potten C.S.;Else K.J.;Finkelman F.D.;Grencis R.K. (01-01-1999. ) Trichuris muris: Host intestinal epithelial cell hyperproliferation during chronic infection is regu.Experimental Parasitology, , 92 (2 ) ,144-153 More Information

Comoy E.;Pestel J.;Stewart G.A.;Finkelman F.;Capron A.;Thyphronitis G. (01-01-1999. ) Do allergens induce type-2 immune responses?.International Archives of Allergy and Immunology, , 118 (2-4 ) ,399-402 More Information

Marinaro M.;Boyaka P.N.;Jackson R.J.;Finkelman F.D.;Kiyono H.;Jirillo E.;McGhee J.R. (01-01-1999. ) Use of intranasal IL-12 to target predominantly Th1 responses to nasal and Th2 responses to oral vac .Journal of Immunology, , 162 (1 ) ,114-121

Gause W.;Ekkens M.;Nguyen D.;Mitro V.;Liu Q.;Finkelman F.;Greenwald R.;Urban J. (01-01-1999. ) The development of CD4+ T effector cells during the type 2 immune response.Immunologic Research, , 20 (1 ) ,55-65 More Information

Shustov A.;Nguyen P.;Finkelman F.;Elkon K.;Via C. (09-15-1998. ) Differential expression of Fas and Fas ligand in acute and chronic graft-versus-host disease: Up-reg .Journal of Immunology, , 161 (6 ) ,2848-2855

Else K.;Finkelman F. (08-01-1998. ) Intestinal nematode parasites, cytokines and effector mechanisms.International Journal for Parasitology, , 28 (8 ) ,1145-1158 More Information

Morris S.;Coffman R.;Finkelman F. (03-20-1998. ) In vivo IL-4 responses to ?IgD antibody (ab) develop normally in the absence of IL-4 priming .FASEB Journal, , 12 (5 ) ,

Comoy E.E.;Pestel J.;Duez C.;Stewart G.A.;Vendeville C.;Fournier C.;Finkelman F.;Capron A.;Thyphronitis G. (03-01-1998. ) The house dust mite allergen, Dermatophagoides pteronyssinus, promotes type 2 responses by modulatin .Journal of Immunology, , 160 (5 ) ,2456-2462

Keane-Myers A.;Gause W.;Finkelman F.;Xhou X.;Wills-Karp M. (01-15-1998. ) Development of murine allergic asthma is dependent upon B7-2 costimulation .Journal of Immunology, , 160 (2 ) ,1036-1043

Valenzona H.;Dhanoa S.;Finkelman F.;Osmond D. (01-01-1998. ) Exogenous interleukin 7 as a proliferative stimulant of early precursor B cells in mouse bone marrow.Cytokine, , 10 (6 ) ,404-412 More Information

Urban J.;Noben-Trauth N.;Donaldson D.;Madden K.;Morris S.;Collins M.;Finkelman F. (01-01-1998. ) IL-13, IL-4R?, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Ni.Immunity, , 8 (2 ) ,255-264 More Information

Campbell K.;Studer E.;Kilmon M.;Lees A.;Finkelman F.;Conrad D. (09-09-1997. ) Induction of B cell apoptosis by co-cross-linking CD23 and sIg involves aberrant regulation of c-myc.International Immunology, , 9 (8 ) ,1131-1140 More Information

Brunet L.R.;Finkelman F.D.;Cheever A.W.;Kopf M.A.;Pearce E.J. (07-15-1997. ) IL-4 Protects Against TNF-?-Mediated Cachexia and Death during Acute Schistosomiasis .Journal of Immunology, , 159 (2 ) ,777-785

Grieder F.B.;Davis B.K.;Zhou X.D.;Chen S.J.;Finkelman F.D.;Gause W.C. (07-07-1997. ) Kinetics of cytokine expression and regulation of host protection following infection with molecular.Virology, , 233 (2 ) ,302-312 More Information

Goldhill J.;Morris S.C.;Maliszewski C.;Urban J.F.;Funk C.D.;Finkelman F.D.;Shea-Donohue T. (05-01-1997. ) Interleukin-4 modulates cholinergic neural control of mouse small intestinal longitudinal muscle .American Journal of Physiology - Gastrointestinal and Liver Physiology, , 272 (5 35-5 ) ,

Gause W.;Chen S.;Greenwald R.;Halvorson M.;Lu P.;Di Zhou X.;Morris S.;Lee K.;June C.;Finkelman F.;Urban J.;Abe R. (05-01-1997. ) CD28 Dependence of T Cell Differentiation to IL-4 Production Varies with the Particular Type 2 Immun .Journal of Immunology, , 158 (9 ) ,4082-4087

Greenwald R.;Lu P.;Halvorson M.;Zhou X.;Chen S.;Madden K.;Perrin P.;Morris S.;Finkelman F.;Peach R.;Linsley P.;Urban J.;Gause W. (05-01-1997. ) Effects of Blocking B7-1 and B7-2 Interactions during a Type 2 in Vivo Immune Response .Journal of Immunology, , 158 (9 ) ,4088-4096

Marinaro M.;Boyaka P.N.;Finkelman F.D.;Kiyono H.;Jackson R.J.;Jirillo E.;McGhee J.R. (02-03-1997. ) Oral but not parenteral interleukin (IL)-12 redirects T helper 2 (Th2)- type responses to an oral va.Journal of Experimental Medicine, , 185 (3 ) ,415-427 More Information

Gavett S.H.;O'Hearn D.J.;Karp C.L.;Patel E.A.;Schofield B.H.;Finkelman F.D.;Wills-Karp M. (02-01-1997. ) Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice .American Journal of Physiology - Lung Cellular and Molecular Physiology, , 272 (2 16-2 ) ,

Hoffman S.;Crutcher J.;Puri S.;Ansari A.;Villinger F.;Franke E.;Singh P.;Finkelman F.;Gately M.;Dutta G.;Sedegah M. (01-17-1997. ) Sterile protection of monkeys against malaria after administration of interleukin-12.Nature Medicine, , 3 (1 ) ,80-83 More Information

Finkelman F.;Maliszewski C. (01-01-1997. ) Enhancing cytokine effects in vivo .Immunologist, , 5 (1 ) ,10-14

Gause W.;Halvorson M.;Lu P.;Greenwald R.;Linsley P.;Urban J.;Finkelman F. (01-01-1997. ) The function of costimulatory molecules and the development of IL-4-producing T cells.Immunology Today, , 18 (3 ) ,115-120 More Information

Morris S.;Finkelman F. (12-01-1996. ) Evidence for IL-12 induction of low-level IFN-? secretion by cells other than T cells or NK cells .FASEB Journal, , 10 (6 ) ,

Wills-Karp M.;Gavett S.H.;Schofield B.;Finkelman F. (12-01-1996. ) Role of interleukin-4 in the development of allergic airway inflammation and airway hyperresponsiven .Advances in Experimental Medicine and Biology, , 409 ,343-347

Cause W.;Lu P.;Zhou X.;Chen S.;Finkelman F.;Urban J. (12-01-1996. ) Either b7-1 or b7-2 interactions can provide the essential b7 costimulatory signals for an in vivo m .FASEB Journal, , 10 (6 ) ,

Greenwald R.;Urban J.;Lu P.;Nguyen H.;Finkelman F.;Gause W. (12-01-1996. ) Rapid upregulation and differential expression of B7 occurs during the course of a primary type 2 in .FASEB Journal, , 10 (6 ) ,

Marinate N.;Boyalca P.;Jackson R.;Finkelman F.;Gatelv M.;Kiyono H.;McGhee J. (12-01-1996. ) Mucosal administration of rmIL-12 to mice modulates TK2-type responses induced by an oral vaccine .FASEB Journal, , 10 (6 ) ,

Morawetz R.A.;Gabriele L.;Rizzo L.V.;Noben-Trauth N.;Kühn R.;Rajewsky K.;Müller W.;Doherty T.M.;Finkelman F.;Coffman R.L.;Morse H.C. (11-01-1996. ) Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse.Journal of Experimental Medicine, , 184 (5 ) ,1651-1661 More Information

Urban J.F.;Fayer R.;Sullivan C.;Goldhill J.;Shea-Donohue T.;Madden K.;Morris S.C.;Katona I.;Gause W.;Ruff M.;Mansfield L.S.;Finkelman F.D. (11-01-1996. ) Local TH1 and TH2 responses to parasitic infection in the intestine: Regulation by IFN-gamma and IL-.Veterinary Immunology and Immunopathology, , 54 (1-4 ) ,337-344 More Information

Lu P.;Urban J.;Di Zhou X.;Chen S.;Madden K.;Moorman M.;Nguyen H.;Morris S.;Finkelman F.;Gause W. (05-01-1996. ) CD40-mediated stimulation contributes to lymphocyte proliferation, antibody production, eosinophilia .Journal of Immunology, , 156 (9 ) ,3327-3333

Keane-Myers A.;Maliszewski C.;Finkelman F.;Nickell S. (04-01-1996. ) Recombinant IL-4 treatment augments resistance to Borrelia burgdorferi infections in both normal sus .Journal of Immunology, , 156 (7 ) ,2488-2494

Grillot D.;Merino R.;Pena J.;Fanslow W.;Finkelman F.;Thompson C.;Núñez G. (02-01-1996. ) bcl-x Exhibits regulated expression during B cell development and activation and modulates lymphocyt.Journal of Experimental Medicine, , 183 (2 ) ,381-391 More Information

Marinaro M.;Boyaka P.;Jackson R.;Finkelman F.;Kiyono H.;McGhee J. (01-01-1996. ) Interleukin-12 alters helper T-cell subsets and antibody profiles induced by the mucosal adjuvant ch.Annals of the New York Academy of Sciences, , 795 ,361-365 More Information

Urban J.;Fayer R.;Chen S.;Gause W.;Gately M.;Finkelman F. (01-01-1996. ) IL-12 protects immunocompetent and immunodeficient neonatal mice against infection with Cryptosporid .Journal of Immunology, , 156 (1 ) ,263-268

Le Gros G.;Schultze N.;Walti S.;Einsle K.;Finkelman F.;Kosco-Vilbois M.;Heusser C. (01-01-1996. ) The development of IgE+ memory B cells following primary IgE immune responses.European Journal of Immunology, , 26 (12 ) ,3042-3047 More Information

Cause W.;Pin L.;Zhou X.;Chen S.;Madden K.;Morris S.;Linsley P.;Finkelman F.;Urban J. (01-01-1996. ) H. polygyrus: B7-independence of the secondary type 2 response.Experimental Parasitology, , 84 (2 ) ,264-273 More Information

Gavett S.;O’Hearn D.;Li X.;Huang S.;Finkelman F.;Wills-Karp M. (11-01-1995. ) Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine e.Journal of Experimental Medicine, , 182 (5 ) ,1527-1536 More Information

Finkelman F. (08-01-1995. ) Relationships among antigen presentation, cytokines, immune deviation, and autoimmune disease.Journal of Experimental Medicine, , 182 (2 ) ,279-282 More Information

Finkelman F.D.;Holmes J.M.;Dukhanina O.I.;Morris S.C. (02-01-1995. ) Cross-linking of membrane immunoglobulln d, in the absence of t cell help, kills mature b cells in v.Journal of Experimental Medicine, , 181 (2 ) ,515-525 More Information

CHEEVER A.;FINKELMAN F.;COX T. (01-01-1995. ) Anti?interleukin?4 treatment diminishes secretion of Th2 cytokines and inhibits hepatic fibrosis in .Parasite Immunology, , 17 (2 ) ,103-109 More Information

Goldhill J.;Finkelman F.;Morris S.;Shea-Donohue T. (01-01-1995. ) Neural control of mouse small intestinal longitudinal muscle: Interactions with inflammatory mediato .Journal of Pharmacology and Experimental Therapeutics, , 274 (1 ) ,72-77

Katona I.;Urban J.;Finkelman F.;Gause W.;Madden K. (01-01-1995. ) Cytokine regulation of intestinal mastocytosis in Nippostrongylus brasiliensis infection .Advances in Experimental Medicine and Biology, , 371 (B ) ,971-973

Urban J.;Maliszewski C.;Madden K.;Katona I.;Finkelman F. (01-01-1995. ) IL-4 treatment can cure established gastrointestinal nematode infections in immunocompetent and immu .Journal of Immunology, , 154 (9 ) ,4675-4684

Eltoum I.A.;Wynn T.A.;Poindexter R.W.;Finkelman F.D.;Lewis F.A.;Sher A.;Cheever A.W. (01-01-1995. ) Suppressive effect of interleukin-4 neutralization differs for granulomas around Schistosoma mansoni .Infection and Immunity, , 63 (7 ) ,2532-2536

Lu P.;Di Zhou X.;Chen S.;Moorman M.;Schoneveld A.;Morris S.;Finkelman F.;Linsley P.;Claassen E.;Gause W. (01-01-1995. ) Requirement of CTLA-4 counter receptors for IL-4 but not IL-10 elevations during a primary systemic .Journal of Immunology, , 154 (3 ) ,1078-1087

Strassmann G.;Patil-Koota V.;Finkelman F.;Fong M.;Kambayashi T. (12-01-1994. ) Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal.Journal of Experimental Medicine, , 180 (6 ) ,2365-2370 More Information

Via C.;Rus V.;Cately M.;Finkelman F. (11-01-1994. ) IL-12 stimulates the development of acute graft-versus-host disease in mice that normally would deve .Journal of Immunology, , 153 (9 ) ,4040-4047

Neta R.;Stiefel S.;Finkelman F.;Herrmann S.;Ali N. (11-01-1994. ) IL-12 protects bone marrow from and sensitizes intestinal tract to ionizing radiation .Journal of Immunology, , 153 (9 ) ,4230-4237

Sedegah M.;Finkelman F.;Hoffman S. (10-25-1994. ) Interleukin 12 induction of interferon ?-dependent protection against malaria.Proceedings of the National Academy of Sciences of the United States of America, , 91 (22 ) ,10700-10702 More Information

Lu P.;Zhou X.;Chen S.;Moorman M.;Morris S.;Finkelman F.;Linsley P.;Urban J.;Gause W. (08-01-1994. ) Ctla-4 ligands are required to induce an in vivo interleukin 4 response to a gastrointestinal nemato.Journal of Experimental Medicine, , 180 (2 ) ,693-698 More Information

Cheever A.;Williams M.;Wynn T.;Finkelman F.;Seder R.;Cox T.;Hieny S.;Caspar P.;Sher A. (07-15-1994. ) Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, .Journal of Immunology, , 153 (2 ) ,753-759

Squire C.;Studer E.;Lees A.;Finkelman F.;Conrad D. (05-01-1994. ) Antigen presentation is enhanced by targeting antigen to the Fc?RII by antigen-anti-Fc?RII conjugate .Journal of Immunology, , 152 (9 ) ,4388-4396

Finkelman F.;Madden K.;Cheever A.;Katona I.;Morris S.;Gately M.;Hubbard B.;Gause W.;Urban J. (05-01-1994. ) Effects of interleukin 12 on immune responses and host protection in mice infected with intestinal n.Journal of Experimental Medicine, , 179 (5 ) ,1563-1572 More Information

Morris S.;Lees A.;Finkelman F. (04-15-1994. ) In vivo activation of naive T cells by antigen-presenting B cells .Journal of Immunology, , 152 (8 ) ,3777-3785

Morris S.;Lees A.;Holmes J.;Jeffries R.;Finkelman F. (04-15-1994. ) Induction of B cell and T cell tolerance in vivo by anti-CD23 mAb .Journal of Immunology, , 152 (8 ) ,3768-3776

Jones R.;Finkelman F.;Hester R.;Kayes S. (02-01-1994. ) Toxocara canis: Failure to Find IgE Receptors (Fc?R) on Eosinophils from Infected Mice Suggests That.Experimental Parasitology, , 78 (1 ) ,64-75 More Information

Morris S.C.;Madden K.B.;Adamovicz J.J.;Gause W.C.;Hubbard B.R.;Gately M.K.;Finkelman F.D. (02-01-1994. ) Effects of IL-12 on in vivo cytokine gene expression and Ig isotype selection .Journal of Immunology, , 152 (3 ) ,1047-1056

Cooke M.;Heath A.;Shokat K.;Zeng Y.;Finkelman F.;Linsley P.;Howard M.;Goodnow C. (02-01-1994. ) Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is block.Journal of Experimental Medicine, , 179 (2 ) ,425-438 More Information

Gavett S.;Chen X.;Finkelman F.;Wills-Karp M. (01-01-1994. ) Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary.American journal of respiratory cell and molecular biology, , 10 (6 ) ,587-593 More Information

Duong T.;Finkelman F.;Singh B.;Strejan G. (01-01-1994. ) Effect of anti-interferon-? monoclonal antibody treatment on the development of experimental allergi.Journal of Neuroimmunology, , 53 (1 ) ,101-107 More Information

Else K.;Finkelman F.;Maliszewski C.;Grencis R. (01-01-1994. ) Cytokine-mediated regulation of chronic intestinal helminth infection.Journal of Experimental Medicine, , 179 (1 ) ,347-351 More Information

Miralles G.D.;Stoeckle M.Y.;McDermott D.F.;Finkelman F.D.;Murray H.W. (01-01-1994. ) Th1 and Th2 cell-associated cytokines in experimental visceral Leishmaniasis .Infection and Immunity, , 62 (3 ) ,1058-1063

Maliszewski C.;Sato T.;Davison B.;Jacobs C.;Finkelman F.;Fanslow W. (01-01-1994. ) In Vivo Biological Effects of Recombinant Soluble lnterleukin-4 Receptor.Proceedings of the Society for Experimental Biology and Medicine, , 206 (3 ) ,233-237 More Information

Lees A.;Finkelman F.;Inman J.;Witherspoon K.;Johnson P.;Kennedy J.;Mond J. (01-01-1994. ) Enhanced immunogenicity of protein-dextran conjugates: I. Rapid stimulation of enhanced antibody res.Vaccine, , 12 (13 ) ,1160-1166 More Information

Grabstein K.;Waldschmidt T.;Finkelman F.;Hess B.;Alpert A.;Boiani N.;Namen A.;Morrissey P. (07-01-1993. ) Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukln 7 monoclonal antibody.Journal of Experimental Medicine, , 178 (1 ) ,257-264 More Information

Via C.;Finkelman F. (06-01-1993. ) Critical role of interleukin-2 in the development of acute graft-versus-host disease.International Immunology, , 5 (6 ) ,565-572 More Information

Yamada H.;June C.;Finkelman F.;Brunswick M.;Ring M.;Lees A.;Mond J. (06-01-1993. ) Persistent calcium elevation correlates with the induction of surface immunoglobulin-mediated B cell.Journal of Experimental Medicine, , 177 (6 ) ,1613-1621 More Information

Barton B.;Finkelman F. (01-01-1993. ) Anti-inflammatory properties of cytokines, 19 November, 1992, New York Academy of Sciences, New York.Agents and Actions, , 39 (1-2 ) , More Information

Thyphronitis G.;Katona I.;Gause W.;Finkelman F. (01-01-1993. ) Germline and productive C? gene expression during in vivo IgE responses .Journal of Immunology, , 151 (8 ) ,4128-4136

Mandler R.;Finkelman F.;Levine A.;Snapper C. (01-01-1993. ) IL-4 induction of IgE class switching by lipopolysaccharide-activated murine B cells occurs predomin .Journal of Immunology, , 150 (2 ) ,407-418

Cheever A.;Xu Y.;Sher A.;Finkelman F.;Cox T.;Macedonia J. (01-01-1993. ) Schistosoma japonicum-infected mice show reduced hepatic fibrosis and eosinophilia and selective inh .Infection and Immunity, , 61 (4 ) ,1288-1292

Urban J.;Madden K.;Cheever A.;Trotta P.;Katona I.;Finkelman F. (01-01-1993. ) IFN inhibits inflammatory responses and protective immunity in mice infected with the nematode paras .Journal of Immunology, , 151 (12 ) ,7086-7094

Sato T.;Widmer M.;Finkelman F.;Madani H.;Jacobs C.;Grabstein K.;Maliszewski C. (01-01-1993. ) Recombinant soluble murine IL-4 receptor can inhibit or enhance IgE responses in vivo .Journal of Immunology, , 150 (7 ) ,2717-2723

Finkelman F.;Madden K.;Morris S.;Holmes J.;Boiani N.;Katona I.;Maliszewski C. (01-01-1993. ) Anti-cytokine antibodies as carrier proteins: Prolongation of in vivo effects of exogenous cytokines .Journal of Immunology, , 151 (3 ) ,1235-1244

Svetic A.;Madden K.;Xia di Zhou;Lu P.;Katona I.;Finkelman F.;Urban J.;Gause W. (01-01-1993. ) A primary intestinal helminthic infection rapidly induces a gut- associated elevation of Th2-associa .Journal of Immunology, , 150 (8 I ) ,3434-3441

Finkelman F.;Villacreses N.;Holmes J. (12-01-1992. ) Role of antigen-specific T cell help in the generation of in vivo antibody responses: II. Sustained .Journal of Immunology, , 149 (12 ) ,3845-3850

Morris S.;Lees A.;Inman J.;Finkelman F. (12-01-1992. ) Role of antigen-specific T cell help in the generation of in vivo antibody responses: I. Antigen-spe .Journal of Immunology, , 149 (12 ) ,3836-3844

Finkelman F.;Lees A.;Morris S. (08-01-1992. ) Antigen presentation by B lymphocytes to CD4+ T lymphocytes in vivo: Importan .Seminars in Immunology, , 4 (4 ) ,247-255

Snapper C.;McLntyre T.;Mandler R.;Pecanha L.;Finkelman F.;Lees A.;Mond J. (05-01-1992. ) Induction of igg3 secretion by interferon ?: A model for t cell-independent class switching in respo.Journal of Experimental Medicine, , 175 (5 ) ,1367-1371 More Information

Finkelman F. (01-01-1992. ) Down, but not out for the count.Current Biology, , 2 (4 ) ,214-215 More Information

Finkelman F.;Urban J. (01-01-1992. ) Cytokines: Making the right choice.Parasitology Today, , 8 (9 ) ,311-314 More Information

Duong T.;Finkelman F.;Strejan G. (01-01-1992. ) Effect of interferon-? on myelin basic protein-specific T cell line proliferation in response to ant.Cellular Immunology, , 145 (2 ) ,311-323 More Information

Campbell K.;Lees A.;Finkelman F.;Conrad D. (01-01-1992. ) Co?crosslinking Fc?RII/CD23 and B cell surface immunoglobulin modulates B cell activation.European Journal of Immunology, , 22 (8 ) ,2107-2112 More Information

Mills F.;Thyphronitis G.;Finkelman F.;Max E. (01-01-1992. ) Ig ?-? isotype switch in IL-4-treated human B lymphoblastoid cells: Evidence for a sequential switch .Journal of Immunology, , 149 (3 ) ,1075-1085

Brunswick M.;Burkhardt A.;Finkelman F.;Bolen J.;Mond J. (01-01-1992. ) Comparison of tyrosine kinase activation by mitogenic and nonmitogenic anti-IgD antibodies .Journal of Immunology, , 149 (7 ) ,2249-2254

Duong T.;St. Louis J.;Gilbert J.;Finkelman F.;Strejan G. (01-01-1992. ) Effect of anti-interferon-? and anti-interleukin-2 monoclonal antibody treatment on the development .Journal of Neuroimmunology, , 36 (2-3 ) ,105-115 More Information

Cheever A.;Finkelman F.;Caspar P.;Heiny S.;Macedonia J.;Sher A. (01-01-1992. ) Treatment with anti-IL-2 antibodies reduces hepatic pathology and eosinophilia in Schistosoma manson .Journal of Immunology, , 148 (10 ) ,3244-3248

Seder R.;Boulay J.;Finkelman F.;Barbier S.;Ben-Sasson S.;Le Gros G.;Paul W. (01-01-1992. ) CD8+ T cells can be primed in vitro to produce IL-4 .Journal of Immunology, , 148 (6 ) ,1652-1656

Urban J.;Madden K.;Svetica A.;Cheever A.;Trotta P.;Gause W.;Katona I.;Finkelman F. (01-01-1992. ) The Importance of Th2 Cytokines in Protective Immunity to Nematodes.Immunological Reviews, , 127 (1 ) ,205-220 More Information

Owens J.D.;Finkelman F.D.;Mountz J.D.;Muchinski J.F. (11-06-1991. ) Nonhomologous recombination at sites within the mouse J(H)-C(?) locus accompanies C? deletion and sw .Molecular and Cellular Biology, , 11 (11 ) ,5660-5670

Finkelman F.;Svetic A.;Gresser I.;Snapper C.;Holmes J.;Trotta P.;Katona I.;Gause W. (11-01-1991. ) Regulation by interferon ? of immunoglobulin isotype selection and lymphokine production in mice.Journal of Experimental Medicine, , 174 (5 ) ,1179-1188 More Information

Tamma S.;Amin A.;Finkelman F.;Chen Y.;Thorbecke G.;Coico R. (10-15-1991. ) IgD receptors on murine T-helper cells bind to Fd and Fc regions of immunoglobulin D.Proceedings of the National Academy of Sciences of the United States of America, , 88 (20 ) ,9233-9237 More Information

Urban J.;Katona I.;Paul W.;Finkelman F. (09-04-1991. ) Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice.Proceedings of the National Academy of Sciences of the United States of America, , 88 (13 ) ,5513-5517 More Information

Snapper C.;Yamaguchi H.;Urban J.;Finkelman F. (09-01-1991. ) Induction of Ly-6A/E expression by murine lymphocytes after in vivo immunization is strictly depende.International Immunology, , 3 (9 ) ,845-852 More Information

Thyphronitis G.;Banchereau J.;Heusser C.;Tsokos G.;Levine A.;Finkelman F. (04-01-1991. ) Kinetics of interleukin-4 induction and interferon-? inhibition of IgE secretion by Epstein-Barr vir.Cellular Immunology, , 133 (2 ) ,408-419 More Information

Seder R.;Paul W.;Dvorak A.;Sharkis S.;Kagey-Sobotka A.;Niv Y.;Finkelman F.;Barbieri S.;Galli S.;Plaut M. (04-01-1991. ) Mouse splenic and bone marrow cell populations that express high-affinity Fc?.Proceedings of the National Academy of Sciences of the United States of America, , 88 (7 ) ,2835-2839 More Information

Urban J.;Katona I.;Finkelman F. (01-01-1991. ) Heligmosomoides polygyrus: CD4+ but not CD8+ T cells r.Experimental Parasitology, , 73 (4 ) ,500-511 More Information

Thyphronitis G.;Max E.;Finkelman F. (01-01-1991. ) Generation and cloning of stable human IgE-secreting cells that have rearranged the C? gene .Journal of Immunology, , 146 (5 ) ,1496-1502

Pecanha L.;Snapper C.;Finkelman F.;Mond J. (01-01-1991. ) Dextran-conjugated anti-Ig antibodies as a model for T cell-independent type 2 antigen-mediated stim .Journal of Immunology, , 146 (3 ) ,833-839

Snapper C.;Hooley J.;Urban J.;Finkelman F. (01-01-1991. ) Lack of Fc?RII expression by murine B cells after in vivo immunization is directly associated with I .Journal of Immunology, , 146 (7 ) ,2161-2168

Weiss E.;Tucker P.;Finkelman F.;Yuan D. (01-01-1991. ) Analysis of immunoglobulin heavy chain ? transcription termination in the production of ?S or ?M mRN.Molecular Immunology, , 28 (7 ) ,687-695 More Information

Ryan J.;LeJeune H.;Mond J.;Finkelman F. (01-01-1991. ) Allostimulatory analysis of a newly-defined and widely-distributed Mls superantigen.Immunogenetics, , 34 (2 ) ,88-100 More Information

Finkelman F.;Pearce E.;Urban J.;Sher A. (01-01-1991. ) Regulation and biological function of helminth-induced cytokine responses.Parasitology Today, , 7 (3 ) ,62-66 More Information

Ungar B.;Kao T.;Burris J.;Finkelman F. (01-01-1991. ) Cryptosporidium infection in an adult mouse model: Independent roles for IFN-? and CD4+&l .Journal of Immunology, , 147 (3 ) ,1014-1022

Finkelman F.;Pearce E.;Urban J.;Sher A. (01-01-1991. ) Regulation and biological function of helminth-induced cytokine responses.Immunology Today, , 12 (3 ) , More Information

Katona I.;Urban J.;Kang S.;Paul W.;Finkelman F. (01-01-1991. ) IL-4 requirements for the generation of secondary in vivo IgE responses .Journal of Immunology, , 146 (12 ) ,4215-4221

Goroff D.;Holmes J.;Bazin H.;Nisol F.;Finkelman F. (01-01-1991. ) Polyclonal activation of the murine immune system by an antibody to IgD. XI. Contribution of membran .Journal of Immunology, , 146 (1 ) ,18-25

Takeishi T.;Martin T.;Katona I.;Finkelman F.;Galli S. (01-01-1991. ) Differences in the expression of the cardipulmonary alterations associated with anti-immunoglobulin .Journal of Clinical Investigation, , 88 (2 ) ,598-608 More Information

May R.;Wheeler H.;Finkelman F.;Uhr J.;Vitetta E. (01-01-1991. ) Intracellular routing rather than cross-linking or rate of internalization determines the potency of.Cellular Immunology, , 135 (2 ) ,490-500 More Information

Seder R.;Plaut M.;Barbieri S.;Urban J.;Finkelman F.;Paul W. (01-01-1991. ) Purified Fc?R+ bone marrow and splenic non-B, non-T cells are highly enriched .Journal of Immunology, , 147 (3 ) ,903-909

Madden K.;Urban J.;Ziltener H.;Schrader J.;Finkelman F.;Katona I. (01-01-1991. ) Antibodies to IL-3 and IL-4 suppress helminth-induced intestinal mastocytosis .Journal of Immunology, , 147 (4 ) ,1387-1391

Finkelman F.;Urban J.;Beckmann M.;Schooley K.;Holmes J.;Katona I. (01-01-1991. ) Regulation of murine in vivo IgG and IgE responses by a monoclonal anti-IL-4 receptor antibody.International Immunology, , 3 (6 ) ,599-607 More Information

Seder R.;le Gros G.;Ben?Sasson S.;Urban J.;Finkelman F.;Paul W. (01-01-1991. ) Increased frequency of interleukin 4?producing T cells as a result of polyclonal priming. Use of a s.European Journal of Immunology, , 21 (5 ) ,1241-1247 More Information

Amin A.;Tamma S.;Oppenheim J.;Finkelman F.;Kieda C.;Coico R.;Thorbecke G. (01-01-1991. ) Specificity of the murine IgD receptor on T cells is for N-linked glycans on IgD molecules.Proceedings of the National Academy of Sciences of the United States of America, , 88 (20 ) ,9238-9242 More Information

Kenny J.;Stall A.;Sieckmann D.;Lamers M.;Finkelman F.;Finch L.;Longo D. (01-01-1991. ) Receptor-mediated elimination of phosphocholine-specific B cells in X-linked immune-deficient mice .Journal of Immunology, , 146 (8 ) ,2568-2577

Svetic A.;Finkelman F.;Jian Y.;Dieffenbach C.;Scott D.;McCarthy K.;Steinberg A.;Gause W. (01-01-1991. ) Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody .Journal of Immunology, , 147 (7 ) ,2391-2397

Thyphronitis G.;Kinoshita T.;Inoue K.;Schweinle J.;Tsokos G.;Metcalf E.;Finkelman F.;Balow J. (01-01-1991. ) Modulation of mouse complement receptors 1 and 2 suppresses antibody responses in vivo .Journal of Immunology, , 147 (1 ) ,224-230

Seder R.;Paul W.;Ben-Sasson S.;Legros G.;Plaut M.;Ben-Sasson S.;Kagey-Sobotka A.;Plaut M.;Finkelman F.;Pierce J. (01-01-1991. ) Production of interleukin-4 and other cytokines following stimulation of mast cell lines and in vivo.International Archives of Allergy and Immunology, , 94 (1-4 ) ,137-140 More Information

Gros G.;Ben-Sasson S.;Seder R.;Finkelman F.;Paul W. (09-01-1990. ) Generation of interleukin 4 (114)-producing cells in vivo and in vitro: IIr2 and ILr4 are required f.Journal of Experimental Medicine, , 172 (3 ) ,921-929 More Information

Kinoshita T.;Thyphronitis G.;Tsokos G.C.;Finkelman F.D.;Hong K.;Sakai H.;Inoue K. (07-01-1990. ) Characterization of murine complement receptor type 2 and its immunological cross-reactivity with ty.International Immunology, , 2 (7 ) ,651-659 More Information

Conrad D.;Ben-Sasson S.;Le Gros G.;Finkelman F.;Paul W. (05-01-1990. ) Infection with Nippostrongylus Brasiliensis or injection of anti-IgD antibodies markedly enhances Fc.Journal of Experimental Medicine, , 171 (5 ) ,1497-1508 More Information

Snapper C.;Finkelman F. (01-01-1990. ) Rapid loss of IgM expression by normal murine B cells undergoing IgG1 and IgE class switching after .Journal of Immunology, , 145 (11 ) ,3654-36660

Snapper C.;Hooley J.;Barbieri S.;Finkelman F. (01-01-1990. ) Murine B cells expressing Thy-1 after in vivo immunization selectively secrete IgE .Journal of Immunology, , 144 (8 ) ,2940-2945

Ryan J.;Lejeune H.;Mond J.;Finkelman F. (01-01-1990. ) Genetic analysis of the presentation of minor lymphocyte-stimulating determinants. II. Differing non .Journal of Immunology, , 144 (7 ) ,2506-2517

Ungar B.;Burris J.;Quinn C.;Finkelman F. (01-01-1990. ) New mouse models for chronic Cryptosporidium infection in immunodeficient hosts .Infection and Immunity, , 58 (4 ) ,961-969

Mountz J.;Mushinski J.;Owens J.;Finkelman F. (01-01-1990. ) The in vivo generation of murine IgD-secreting cells is accompanied by deletion of the C? gene and o .Journal of Immunology, , 145 (5 ) ,1583-1591

Scott D.;Gause W.;Finkelman F.;Steinberg A. (01-01-1990. ) Anti-CD3 antibody induces rapid expression of cytokine genes in vivo .Journal of Immunology, , 145 (7 ) ,2183-2188

Tsokos G.;Lambris J.;Finkelman F.;Anastassiou E.;June C. (01-01-1990. ) Monovalent ligands of complement receptor 2 inhibit whereas polyvalent ligands enhance anti-Ig-induc .Journal of Immunology, , 144 (5 ) ,1640-1645

May R.;Finkelman F.;Wheeler H.;Uhr J.;Vitetta E. (01-01-1990. ) Evaluation of ricin A chain-containing immunotoxins directed against different epitopes on the ?-cha .Journal of Immunology, , 144 (9 ) ,3637-3642

Ben-Sasson S.;Le Gros G.;Conrad D.;Finkelman F.;Paul W. (01-01-1990. ) IL-4 production by T cells from naive donors. IL-2 is required for IL-4 production .Journal of Immunology, , 145 (4 ) ,1127-1136

Finkelman F.;Goroff D.;Fultz M.;Morris S.;Holmes J.;Mond J. (01-01-1990. ) Polyclonal activation of the murine immune system by an antibody to IgD. X. Evidence that the precur .Journal of Immunology, , 145 (11 ) ,3562-3569

Lees A.;Morris S.;Thyphronitis G.;Holmes J.;Inman J.;Finkelman F. (01-01-1990. ) Rapid stimulation of large specific antibody responses with conjugates of antigen and anti-IgD antib .Journal of Immunology, , 145 (11 ) ,3594-3600

Tsokos G.C.;Kinoshita T.;Thyphronitis G.;Patel A.D.;Dickler H.B.;Finkelman F.D. (01-01-1990. ) Interactions between murine B lymphocyte surface membrane molecules. Loaded but not free receptors f .Journal of Immunology, , 144 (1 ) ,239-243

Le Gros G.;Ben-Sasson S.;Conrad D.;Clark-Lewis I.;Finkelman F.;Plaut M.;Paul W. (01-01-1990. ) IL-3 Promotes production of IL-4 by splenic non-B, non-T cells in response to Fc receptor cross-link .Journal of Immunology, , 145 (8 ) ,2500-2506

Finkelman F.;Holmes J.;Katona I.;Urban J.;Beckmann M.;Park L.;Schooley K.;Coffman R.;Mosmann T.;Paul W. (01-01-1990. ) Lymphokine control of in vivo immunoglobulin isotype selection .Annual Review of Immunology, , 8 ,303-330

Finkelman F.;Katona I.;Urban J.;Paul W. (12-01-1989. ) Control of in vivo IgE production in the mouse by interleukin 4. Ciba Foundation symposium, , 147 ,3-17; discussion 17

Snapper C.;Hooley J.;Atasoy U.;Finkelman F.;Paul W. (11-02-1989. ) Differential regulation of murine B cell Fc?RII expression by CD4+ T helper s .Journal of Immunology, , 143 (7 ) ,2133-2141

Fultz M.;Finkelman F.;Metcalf E. (01-01-1989. ) Altered expression of the Salmonella typhimurium-specific B-cell repertoire in mice chronically trea .Infection and Immunity, , 57 (2 ) ,432-437

Brunswick M.;June C.;Finkelman F.;Mond J. (01-01-1989. ) Different patterns of inositol polyphosphate production are seen in B lymphocytes after cross-linkin .Journal of Immunology, , 143 (5 ) ,1414-1421

Fultz M.;Carman J.;Finkelman F.;Mond J. (01-01-1989. ) Neonatal suppression with anti-Ia antibody. III. In vivo responses to the type 2 antigen TNP-Ficoll .Journal of Immunology, , 143 (2 ) ,403-406

Thyphronitis G.;Tsokos G.;June C.;Levine A.;Finkelman F. (01-01-1989. ) IgE secretion by Epstein-Barr virus-infected purified human B lymphocytes is stimulated by interleuk.Proceedings of the National Academy of Sciences of the United States of America, , 86 (14 ) ,5580-5584 More Information

Mond J.;Hunter K.;Kenny J.;Finkelman F.;Witherspoon K. (01-01-1989. ) 8-mercaptoguanosine-mediated enhancement of in vivo IgGl, IgG2 and IgG3 antibody responses to polysa.Immunopharmacology, , 18 (3 ) ,205-212 More Information

Finkelman F.;Holmes J.;Urban J.;Paul W.;Katona I. (01-01-1989. ) T help requirements for the generation of an in vivo IgE response: A late acting form of T cell help .Journal of Immunology, , 142 (2 ) ,403-408

Brunswick M.;June C.;Finkelman F.;Dintzis H.;Inman J.;Mond J. (01-01-1989. ) Surface immunoglobulin-mediated B-cell activation in the absence of detectable elevations in intrace.Proceedings of the National Academy of Sciences of the United States of America, , 86 (17 ) ,6724-6728 More Information

Kenny J.;Finkelman F.;Macchiarini F.;Kopp W.;Storb U.;Longo D. (01-01-1989. ) Alteration of the B cell surface phenotype, immune response to phosphocholine and the B cell reperto .Journal of Immunology, , 142 (12 ) ,4466-4474

Mushinski J.F.;Mountz J.D.;Pierce J.H.;Pumphrey J.G.;Skurla R.M.;Finkelman F.D.;Givol D.;Davidson W.F. (12-01-1988. ) Expression of the murine proto-oncogene bcl-2 is stage specific and cell-type specific. Current topics in microbiology and immunology, , 141 ,332-336

Goroff D.;Finkelman F. (01-01-1988. ) Activation of B cells in vivo by a Fab/Fc fragment of a monoclonal anti-IgD antibody requires an int .Journal of Immunology, , 140 (9 ) ,2919-2924

Snapper C.;Finkelman F.;Paul W. (01-01-1988. ) Differential regulation of iggi and ige synthesis by interleukin 4.Journal of Experimental Medicine, , 167 (1 ) ,183-196 More Information

Katona I.;Urban J.;Finkelman F. (01-01-1988. ) The role of L3T4+ and Lyt-2+ T cells in the IgE respon .Journal of Immunology, , 140 (9 ) ,3206-3211

Snapper C.;Finkelman F.;Paul W. (01-01-1988. ) Regulation of IgG1 and IgE Production by Interleukin 4.Immunological Reviews, , 102 (1 ) ,51-75 More Information

Ryan J.;Mond J.;Finkelman F. (01-01-1988. ) Genetic analysis of the presentation of minor lymphocyte stimulating determinants I. Combined import .Journal of Immunology, , 141 (4 ) ,1063-1073

Wilson H.;Greenblatt D.;Finkelman F.;Chused T. (01-01-1988. ) Optical measurement in single cells of membrane potential changes linked to T and B lymphocyte antig .Society of General Physiologists series, , 43 ,253-263

Mountz J.;Gause W.;Finkelman F.;Steinberg A. (01-01-1988. ) Prevention of lymphadenopathy in MRL-lpr/lpr mice by blocking peripheral lymph node homing with Mel- .Journal of Immunology, , 140 (9 ) ,2943-2949

Deuster P.;Curiale A.;Cowan M.;Finkelman F. (01-01-1988. ) Exercise-induced changes in populations of peripheral blood mononuclear cells.Medicine and Science in Sports and Exercise, , 20 (3 ) ,276-280 More Information

Finkelman F.;Katona I.;Mosmann T.;Coffman R. (01-01-1988. ) IFN-? regulates the isotypes of Ig secreted during in vivo humoral immune responses .Journal of Immunology, , 140 (4 ) ,1022-1027

Ryan J.;Thompson C.;Mond J.;Finkelman F. (01-01-1988. ) AUGMENTED IN VITRO PRESENTATION OF Mls DETERMINANTS AFTER ANTI?IMMUNOGLOBULIN?INDUCED B CELL ACTIVAT.International Journal of Immunogenetics, , 15 (1-3 ) ,121-133 More Information

Tsokos G.;Thyphronitis G.;Jack R.;Finkelman F. (01-01-1988. ) Ligand-loaded but not free complement receptors for C3b/C4b and C3d co-cap with cross-linked B cell .Journal of Immunology, , 141 (4 ) ,1261-1266

Amin A.;Coico R.;Finkelman F.;Siskind G.;Thorbecke G. (01-01-1988. ) Release of IgD-binding factor by T cells under the influence of interleukin 2, interleukin 4, or cro.Proceedings of the National Academy of Sciences of the United States of America, , 85 (23 ) ,9179-9183 More Information

McMillan V.;Dennis G.;Glimcher L.;Finkelman F.;Mond J. (01-01-1988. ) Corticosteroid induction of Ig+Ia- B cells in vitro is .Journal of Immunology, , 140 (8 ) ,2549-2555

Snapper C.;Finkelman F.;Stefany D.;Conrad D.;Paul W. (01-01-1988. ) IL-4 induces co-expression of intrinsic membrane IgG1 and IgE by murine B cells stimulated with lipo .Journal of Immunology, , 141 (2 ) ,489-498

Gause W.;Takashi T.;Mountz J.;Finkelman F.;Steinberg A. (01-01-1988. ) Activation of CD 4-, CD 8- thymocytes with IL 4 vs IL .Journal of Immunology, , 141 (7 ) ,2240-2245

Coico R.;Finkelman F.;Swenson C.;Siskind G.;Thorbecke G. (01-01-1988. ) Exposure to crosslinked IgD induces receptors for IgD on T cells in vivo and in vitro.Proceedings of the National Academy of Sciences of the United States of America, , 85 (2 ) ,559-563 More Information

Brunswick M.;Finkelman F.;Highet P.;Inman J.;Dintzis H.;Mond J. (01-01-1988. ) Picogram quantities of anti-Ig antibodies coupled to dextran induce B cell proliferation .Journal of Immunology, , 140 (10 ) ,3364-3372

Finkelman F.;Katona I.;Urban J.;Holmes J.;Ohara J.;Tung A.;Sample vG. J.;Paul W. (01-01-1988. ) IL-4 is required to generate and sustain in vivo IgE responses .Journal of Immunology, , 141 (7 ) ,2335-2341

Coffman R.;Seymour B.;Lebman D.;Hiraki D.;Christiansen J.;Shrader B.;Cherwinski H.;Savelkoul H.;Finkelman F.;Bond M.;Mosmann T. (01-01-1988. ) The Role of Helper T Cell Products in Mouse B Cell Differentiation and Isotype Regulation.Immunological Reviews, , 102 (1 ) ,5-28 More Information

Dennis G.J.;Mizuguchi J.;McMillan V.;Finkelman F.D.;Ohara J.;Mond J.J. (08-19-1987. ) Comparison of the calcium requirement for the induction and maintenance of B cell class II molecule .Journal of Immunology, , 138 (12 ) ,4307-4312

Alexander Wilson H.;Greenblatt D.;Poenie M.;Finkelman F.;Tsien R. (08-01-1987. ) Crosslinkage of B lymphocyte surface immunoglobulin by anti-Ig or antigen induces prolonged oscillat.Journal of Experimental Medicine, , 166 (2 ) ,601-606 More Information

Ryan J.;Miner D.;Mond J.;Finkelman F.;Woody J. (06-05-1987. ) Regulation of the in vitro presentation of minor lymphocyte stimulating determinants by major histoc .Journal of Immunology, , 138 (8 ) ,2392-2401

Wilson H.;Greenblatt D.;Taylor C.;Putney J.;Tsien R.;Finkelman F.;Chused T. (05-19-1987. ) The B lymphocyte calcium response to anti-Ig is diminished by membrane immunoglobulin cross-linkage .Journal of Immunology, , 138 (6 ) ,1712-1718

Weber R.;Finkelman F. (01-01-1987. ) Increased expression of the B lymphocyte receptor for transferrin is stimulated by in vivo crosslink.Cellular Immunology, , 104 (2 ) ,400-408 More Information

Fultz M.;Finkelman F.;Metcalf E. (01-01-1987. ) Comparison of the clonal diversity of the B cell repertoires in adult mice that differ in the expres.European Journal of Immunology, , 17 (8 ) ,1137-1143 More Information

Ryan J.;Mond J.;Finkelman F. (01-01-1987. ) The Mls(d)-defined primary mixed lymphocyte reaction: A composite response to Mlsa.Journal of Immunology, , 138 (12 ) ,4085-4092

Laurindo I.;Finkelman F.D.;Mizuguchi J.;Mond J.J. (01-01-1987. ) B-cell activation stimulated by monoclonal anti-Lyb2.1 antibody is mediated through a receptor disti.Cellular Immunology, , 108 (2 ) ,473-482 More Information

Finkelman F.;Snapper C.;Mountz J.;Katona I. (01-01-1987. ) Polyclonal activation of the murine immune system by a goat antibody to mouse IgD. IX. Induction of .Journal of Immunology, , 138 (9 ) ,2826-2830

Abe R.;Ryan J.;Finkelman F.;Hodes R. (01-01-1987. ) T cell recognition of Mls. T cell clones demonstrate polymorphism between Mlsa.Journal of Immunology, , 138 (2 ) ,373-379

Mountz J.;Smith J.;Snapper C.;Mushinski J.;Finkelman F. (01-01-1987. ) Polyclonal activation of the murine immune system by an antibody to IgD. VIII. Stimulation of IgD se .Journal of Immunology, , 139 (7 ) ,2172-2178

Mond J.;Feuerstein N.;Finkelman F.;Huang F.;Huang K.;Dennis G. (01-01-1987. ) B-lymphocyte activation mediated by anti-immunoglobulin antibody in the absence of protein kinase C.Proceedings of the National Academy of Sciences of the United States of America, , 84 (23 ) ,8588-8592 More Information

Chused T.;Wilson H.;Greenblatt D.;Ishida Y.;Edison L.;Tsien R.;Finkelman F. (01-01-1987. ) Flow cytometric analysis of murine splenic B lymphocyte cytosolic free calcium response to anti?IgM .Cytometry, , 8 (4 ) ,396-404 More Information

Dennis G.;June C.H.;Mizuguchi J.;Ohara J.;Witherspoon K.;Finkelman F.D.;McMillan V.;Mond J.J. (01-01-1987. ) Glucocorticoids suppress calcium mobilization and phospholipid hydrolysis in anti-Ig antibody-stimul .Journal of Immunology, , 139 (8 ) ,2516-2523

Alizadeh H.;Urban J.;Katona I.;Finkelman F. (12-01-1986. ) Cells containing IgE in the intestinal mucosa of mice infected with the nematode parasite Trichinell .Journal of Immunology, , 137 (8 ) ,2555-2560

Mond J.;Carman J.;Sarma C.;Ohara J.;Finkelman F. (12-01-1986. ) Interferon-? suppresses B cell stimulation factor (BSF-1) induction of class II MHC determinants on .Journal of Immunology, , 137 (11 ) ,3534-3537

Finkelman F.;Ohara J.;Goroff D.;Smith J.;Villacreses N.;Mond J.;Paul W. (12-01-1986. ) Production of BSF-1 during an in vivo, T-dependent immune response .Journal of Immunology, , 137 (9 ) ,2878-2885

Goroff D.;Stall A.;Mond J.;Finkelman F. (01-01-1986. ) In vitro and in vivo B lymphocyte-activating properties of monoclonal anti-? antibodies. I. Determin .Journal of Immunology, , 136 (7 ) ,2382-2392

Finkelman F.;Malek T.;Shevach E.;Mond J. (01-01-1986. ) In vivo and in vitro expression of an interleukin 2 receptor by murine B and T lymphocytes .Journal of Immunology, , 137 (7 ) ,2252-2259

Finkelman F.;Katona I.;Urban J.;Snapper C.;Ohara J.;Paul W. (01-01-1986. ) Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stim.Proceedings of the National Academy of Sciences of the United States of America, , 83 (24 ) ,9675-9678 More Information

Mond J.;Finkelman F.;Sarma C.;Ohara J.;Serrate S. (12-01-1985. ) Recombinant interferon-? inhibits the B cell proliferative response stimulated by soluble but not by .Journal of Immunology, , 135 (4 ) ,2513-2517

Mond J.;Thompson C.;Finkelman F.;Farrar J.;Schaefer M.;Robb R. (07-11-1985. ) Affinity-purified interleukin 2 induces proliferation of large but not small B cells.Proceedings of the National Academy of Sciences of the United States of America, , 82 (5 ) ,1518-1521 More Information

Thompson C.;Schaefer M.;Finkelman F.;Scher I.;Farrar J.;Mond J. (03-06-1985. ) T-cell-derived B cell growth factor(s) can induce stimulation of both resting and activated B cells .Journal of Immunology, , 134 (1 ) ,369-374

Hunter K.W.;Brimfield A.A.;Miller M.;Finkelman F.D.;Chu S.F. (02-27-1985. ) Preparation and characterization of monoclonal antibodies to the trichothecene mycotoxin T-2 .Applied and Environmental Microbiology, , 49 (1 ) ,168-172

Smith-Gill S.;Finkelman F.;Potter M. (01-01-1985. ) [7] Plasmacytomas and murine immunoglobulins.Methods in Enzymology, , 116 (C ) ,121-145 More Information

Katona I.;Urban J.;Finkelman F. (01-01-1985. ) B cells that simultaneously express surface IgM and IgE in Nippostrongylus brasiliensis-infected SJA.Proceedings of the National Academy of Sciences of the United States of America, , 82 (2 ) ,511-515 More Information

Dennis G.;Finkelman F.;Mond J. (01-01-1985. ) Corticosteroid decrease expression of B cell sIa on resting but not activated B cells .Federation Proceedings, , 44 (4 ) ,

Finkelman F.;Malek T.;Shevach E.;Mond J. (01-01-1985. ) B cell IL2 receptor (IL2R) expression in vivo and in vitro .Federation Proceedings, , 44 (5 ) ,

Johnson D.;Diehl A.;Finkelman F.;Cattau E. (01-01-1985. ) Crohn's Disease and Systemic Lupus Erythematosus.The American Journal of Gastroenterology, , 80 (11 ) ,869-870 More Information

Thiele C.;Owens J.;Finkelman F.;Mushinski J. (01-01-1985. ) Mouse IgD half molecules with shortened IgD heavy chain result from alterations within C? locus .Journal of Immunology, , 134 (2 ) ,1251-1256

Goroff D.;Stall A.;Mond J.;Finkelman F. (01-01-1985. ) Determinants of B cell activating ability of monoclonal anti-IgD antibodies .Federation Proceedings, , 44 (4 ) ,

Finkelman F.;Smith J.;Villacreses N.;Metcalf E. (01-01-1985. ) Polyclonal activation of the murine immune system by an antibody to IgD. VI. Influence of doses of g.European Journal of Immunology, , 15 (4 ) ,315-320 More Information

Thompson C.;Scher I.;Schaefer M.;Lindsten T.;Finkelman F.;Mond J. (12-01-1984. ) Size-dependent B lymphocyte subpopulations: Relationship of cell volume to surface phenotype, cell c .Journal of Immunology, , 133 (5 ) ,2333-2342

Katona I.;Urban J.;Titus J.;Stephany D.;Segal D.;Finkelman F. (10-11-1984. ) Characterization of murine lymphocyte IgE receptors by flow microfluorometry .Journal of Immunology, , 133 (3 ) ,1521-1528

Titus J.;Finkelman F.;Stephany D.;Jones J.;Segal D. (09-20-1984. ) Quantitative analysis of Fc? receptors on murine spleen cell populations by using dual parameter flo .Journal of Immunology, , 133 (2 ) ,556-561

Sieckmann D.;Finkelman F.;Thompson C.;Scher I. (04-15-1984. ) Activation of mouse lymphocytes by anti-immunoglobulin. IV. Stimulation with soluble heterologous an.Cellular Immunology, , 85 (1 ) ,1-14 More Information

Lindsten T.;Thompson C.B.;Finkelman F.D.;Andersson B.;Scher I. (02-23-1984. ) Changes in the expression of B cell surface markers on complement receptor-positive and complement r .Journal of Immunology, , 132 (1 ) ,235-239

Weber R.;Finkelman F. (01-01-1984. ) Increased expression of transferrin receptor on B cells after in vivo cross-linking of surface IgD .Federation Proceedings, , 43 (6 ) ,

Finkelman F.;Vitetta E. (01-01-1984. ) Role of surface immunoglobulin in B lymphocyte activation .Federation Proceedings, , 43 (11 ) ,2624-2632

Boling E.;Nussenblatt R.;Finkelman F. (01-01-1984. ) The effects of CSA upon humoral immunity in mice .Federation Proceedings, , 43 (6 ) ,

Flotte T.J.;Finkelman F.D.;Jeanette Thorbecke G. (01-01-1984. ) Polyclonal activation of the murine immune system by an antibody to IgD V. Effect on germinal center.European Journal of Immunology, , 14 (8 ) ,725-728 More Information

Fultz M.;Finkelman F.;Mond J. (01-01-1984. ) In vivo administration of anti-I-A antibody induces the internalization of B cell surface I-A and I- .Journal of Immunology, , 133 (1 ) ,91-97

Finkelman F.;Smith J.;Villacreses N. (01-01-1984. ) The role of antigen specific T help (ASTH) in an in vivo antibody response .Federation Proceedings, , 43 (6 ) ,

Mond J.;Thompson C.;Finkelman F. (01-01-1984. ) Immuno-affinity purified interleukin 2 (IL2) induces proliferation of large but not small B cells .Federation Proceedings, , 43 (6 ) ,

Finkelman F.;Smith J.;Villacreses N.;Metcalf E. (01-01-1984. ) Polyclonal activation of the murine immune system by an antibody to IgD. VII. Demonstration of the r .Journal of Immunology, , 133 (2 ) ,550-555

Lindsten T.;Finkelman F.D.;Thompson C.B.;Andersson B.;Scher I. (01-01-1984. ) Surface immunoglobulin phenotype of complement receptor?positive and complement receptor?negative B .European Journal of Immunology, , 14 (4 ) ,329-335 More Information

Mond J.J.;Thompson C.;Schaefer M.;Finkelman F.D.;Robb R. (01-01-1984. ) Immuno affinity purified interleukin 2 (IL2) induces B cell growth. Current Topics in Microbiology and Immunology, , 113 ,102-103

Mond J.;Norton G.;Paul W.;Scher I.;Finkelman F.;House S.;Schaefer M.;Mongini P.;Hansen C.;Bona C. (11-01-1983. ) Establishment of an inbred line of mice that express a synergistic immune defect precluding in vitro.Journal of Experimental Medicine, , 158 (5 ) ,1401-1414 More Information

Katona I.;Urban J.;Scher I.;Kanellopoulos-Langevin C.;Finkelman F. (03-03-1983. ) Induction of an IgE response in mice by Nippostrogylus brasiliensis: Characterization of lymphoid ce .Journal of Immunology, , 130 (1 ) ,350-356

Yaffe L.;Finkelman F. (01-01-1983. ) Induction of a B-lymphocyte receptor for a T cell-replacing factor by the crosslinking of surface Ig.Proceedings of the National Academy of Sciences of the United States of America, , 80 (1 ) ,293-297 More Information

Muul L.;Mond J.;Finkelman F. (01-01-1983. ) Polyclonal activation of the murine immune system by an antibody to IgD III. Ontogeny.European Journal of Immunology, , 13 (11 ) ,900-905 More Information

Scher I.;Titus J.;Finkelman F. (01-01-1983. ) The ontogeny and distribution of B cells in normal and mutant immune-defective CBA/N mice: Two param .Journal of Immunology, , 130 (2 ) ,619-625

Metcalf E.;Mond J.;Finkelman F. (01-01-1983. ) Effects of neonatal anti-? antibody treatment on the murine immune system. II. Functional capacity o .Journal of Immunology, , 131 (2 ) ,601-605

Finkelman F.;Mond J.;Metcalf E. (01-01-1983. ) Effects of neonatal anti-? antibody treatment on the murine immune system. I. Suppression of develop .Journal of Immunology, , 131 (2 ) ,593-600

Ryan J.;Mond J.;Finkelman F.;Scher I. (01-01-1983. ) Enhancement of the mixed lymphocyte reaction by in vivo treatment of stimulator spleen cells with an .Journal of Immunology, , 130 (6 ) ,2534-2541

Muul L.;Scher I.;Mond J.;Finkelman F. (01-01-1983. ) Polyclonal activation of the murine immune system by an antibody to IgD. IV. In vivo activation of B .Journal of Immunology, , 131 (5 ) ,2226-2231

Mond J.;Schaefer M.;Smith J.;Finkelman F. (01-01-1983. ) Lyb-5- B cells of CBA/N mice can be induced to synthesize DNA by culture with .Journal of Immunology, , 131 (5 ) ,2107-2109

Thompson C.;Ryan J.;Sieckmann D.;Finkelman F.;Mond J.;Scher I. (01-01-1983. ) A method for size separation of murine spleen cells using counterflow centrifugation.Journal of Immunological Methods, , 63 (3 ) ,299-307 More Information

Fultz M.;Scher I.;Finkelman F.;Kincade P.;Mond J. (10-25-1982. ) Neonatal suppression with anti-Ia antibody. I. Suppression of murine B lymphocyte development .Journal of Immunology, , 129 (3 ) ,992-995

Finkelman F.;Scher I.;Mond J.;Kung J.;Metcalf E. (10-11-1982. ) Polyclonal activation of the murine immune system by an antibody to IgD. I. Increase in cell size an .Journal of Immunology, , 129 (2 ) ,629-637

Finkelman F.;Scher I.;Mond J.;Kessler S.;Kung J.;Metcalf E. (10-11-1982. ) Polyclonal activation of the murine immune system by an antibody to IgD. II. Generation of polyclona .Journal of Immunology, , 129 (2 ) ,638-646

Yaffe L.;Finkelman F. (01-01-1982. ) POSSIBLE INDUCTION OF A TRF RECEPTOR BY ANTI?IgD ANTIBODY.Annals of the New York Academy of Sciences, , 399 (1 ) ,402-404 More Information

Mond J.;Finkelman F. (01-01-1982. ) ANTI?IgD INDUCED INCREASE IN sIa IS ASSOCIATED WITH AN INCREASE IN B?CELL RECEPTIVITY TO HELP AND/OR.Annals of the New York Academy of Sciences, , 399 (1 ) ,221-226 More Information

Sieckmann D.;Finkelman F.;Scher I. (01-01-1982. ) IgD AS A RECEPTOR IN SIGNALING THE PROLIFERATION OF MOUSE B?LYMPHOCYTES.Annals of the New York Academy of Sciences, , 399 (1 ) ,277-289 More Information

Dickler H.B.;Kubicek M.T.;Finkelman F.D. (01-01-1982. ) Interactions between lymphocyte membrane molecules. II. Characterization of an interaction between B .Journal of Immunology, , 128 (3 ) ,1271-1277

Ryan J.;Mond J.;Finkelman F.;Scher I. (01-01-1982. ) ANTI?IgD TREATED STIMULATOR SPLEEN CELLS ENHANCE THE MURINE MIXED LYMPHOCYTE REACTION.Annals of the New York Academy of Sciences, , 399 (1 ) ,397-399 More Information

Muul L.;Scher I.;Mond J.;Finkelman F. (01-01-1982. ) IN VIVO POLYCLONAL ACTIVATION OF IMMUNE DEFECTIVE B?LYMPHOCYTES BY AN ANTIBODY TO IgD.Annals of the New York Academy of Sciences, , 399 (1 ) ,390-391 More Information

Metcalf E.;Mond J.;Scher I.;LaVeck M.;Finkelman F. (01-01-1982. ) B?CELL FUNCTION IN MICE TREATED WITH ANTI?IgD FROM BIRTH.Annals of the New York Academy of Sciences, , 399 (1 ) ,351-359 More Information

Scher I.;Titus J.;Sharrow S.;Mond J.;Finkelman F. (01-01-1982. ) THE DISTRIBUTION OF SURFACE IgD ON B?LYMPHOCYTES OF MICE: TWO PARAMETERON CORRELATION WITH SURFACE I.Annals of the New York Academy of Sciences, , 399 (1 ) ,204-220 More Information

Winfield J.;Cohen P.;Bradley L.;Finkelman F.;Eisenberg R.;Wistar R.;Whisnant J. (01-01-1982. ) IgM cryoprecipitation and anti-immunoglobulin activity in dysgammaglobulinemia type I.Clinical Immunology and Immunopathology, , 23 (1 ) ,58-69 More Information

Mond J.;Scher I.;Cossman J.;Kessler S.;Mongini P.;Hansen C.;Finkelman F.;Paul W. (01-01-1982. ) Role of the thymus in directing the development of a subset of B lymphocytes.Journal of Experimental Medicine, , 155 (3 ) ,924-936 More Information

Finkelman F.;Muul L.;Yaffe L.;Scher I.;Mond J.;Kessler S.;Ryan J.;Kung J.;Metcalf E. (01-01-1982. ) STIMULATION OF THE MURINE IMMUNE SYSTEM BY ANTI?IgD ANTIBODIES: A POLYCLONAL MODEL OF B?LYMPHOCYTE A.Annals of the New York Academy of Sciences, , 399 (1 ) ,316-328 More Information

Basham T.Y.;Toyoshima S.;Finkelman F.;Waxdal M.J. (09-01-1981. ) A series of murine interleukin molecules which stimulate both murine and human lymphocytes. I. Produ.Cellular Immunology, , 63 (1 ) ,118-133 More Information

Finkelman F.;Kessler S.;Mushinski J.;Potter M. (01-01-1981. ) IgD-secreting murine plasmacytomas: Identification and partial characterization of two IgD myeloma p .Journal of Immunology, , 126 (2 ) ,680-687

Mond J.;Seghal E.;Kung J.;Finkelman F. (01-01-1981. ) Increased expression of I-region-associated antigen (Ia) on B cells after cross-linking of surface i .Journal of Immunology, , 127 (3 ) ,881-887

Woods V.;Kessler S.;Finkelman F.;Lieberman R.;Scher I.;Paul W. (12-01-1980. ) IgD allotypic determinants. I. Determinants expressed on murine IgD of the a allotype .Journal of Immunology, , 125 (6 ) ,2699-2707

Mushinski J.;Blattner F.;Owens J.;Finkelman F.;Kessler S.;Fitzmaurice L.;Potter M.;Tucker P. (12-01-1980. ) Mouse immunoglobulin D: Construction and characterization of a cloned ? chain cDNA.Proceedings of the National Academy of Sciences of the United States of America, , 77 (12 II ) ,7405-7409 More Information

Hunter K.;Finkelman F.;Strickland G.;Sayles P.;Scher I. (10-27-1980. ) Murine malaria: Analysis of erythrocyte surface-bound immunoglobulin by flow microfluorimetry .Journal of Immunology, , 125 (1 ) ,169-174

Mond J.;Kessler S.;Finkelman F.;Paul W.;Scher I. (07-04-1980. ) Heterogeneity of Ia expression on normal B cells, neonatal B cells, and on cells from B cell-defecti .Journal of Immunology, , 124 (4 ) ,1675-1682

Finkelman F.D.;Woods V.L.;Wilburn S.B. (01-01-1980. ) Augmentation of in vitro humoral immune responses in the mouse by an antibody to IgD .Journal of Experimental Medicine, , 152 (3 ) ,493-506

Scher I.;Berning A.;Kessler S.;Finkelman F. (01-01-1980. ) Development of B lymphocytes in the mouse: Studies of the frequency and distribution of surface IgM .Journal of Immunology, , 125 (4 ) ,1686-1693

Isakson P.C.;Uhr J.W.;Krolick K.A.;Finkelman F.;Vitetta E.S. (01-01-1980. ) Acquisition of cell surface IgD after in vitro culture of neoplastic B cells from the murine tumor B.Journal of Experimental Medicine, , 151 (3 ) ,749-754 More Information

Finkelman F.;Mond J.;Woods V.;Wilburn S.;Berning A.;Sehgal E.;Scher I. (01-01-1980. ) Effects of Anti?Immunoglobulin Antibodies on Murine B Lymphocytes and Humoral Immune Responses.Immunological Reviews, , 52 (1 ) ,55-74 More Information

Ginsburg W.;Finkelman F.;Lipsky P. (12-01-1979. ) Circulating and pokeweed mitogen-induced immunoglobulin-secreting cells in systemic lupus erythemato .Clinical and Experimental Immunology, , 35 (1 ) ,76-88

Kessler S.;Woods V.;Finkelman F.;Scher I. (12-01-1979. ) Membrane orientation and location of multiple and distinct allotypic determinants of mouse lymphocyt .Journal of Immunology, , 123 (6 ) ,2772-2778

Hunter K.;Finkelman F.;Strickland G.;Sayles P.;Scher I. (12-01-1979. ) Defective resistance to Plasmodium yoelii in CBA/N mice .Journal of Immunology, , 123 (1 ) ,133-137

Finkelman F.;Scher I. (01-01-1979. ) Rhesus monkey B lymphocyte surface immunoglobulin: Analysis with a fluorescence-activated cell sorte .Journal of Immunology, , 122 (5 ) ,1757-1762

Finkelman F.;Lipsky P. (01-01-1979. ) The Role of Cell Membrane Immunoglobulin in Primate B Lymphocyte Differentiation.Immunological Reviews, , 45 (1 ) ,117-139 More Information

Finkelman F.;Kessler S.;Scher I. (01-01-1979. ) Preparation of an antibody to mouse serum IgD .Journal of Immunology, , 123 (2 ) ,952-954

Basham T.Y.;Toyoshima S.;Finkelman F.;Waxdal M.J. (01-01-1979. ) Production of helper factor by murine T cells stimulated with the pokeweed mitogen PA-2 .Journal of Supramolecular and Cellular Biochemistry, , Suppl.3 ,760

Finkelman F.;Woods V.;Berning A.;Scher I. (01-01-1979. ) Demonstration of mouse serum IgD .Journal of Immunology, , 123 (3 ) ,1253-1259

Finkelman F.;Lipsky P. (12-01-1978. ) Immunoglobulin secretion by human splenic lymphocytes in vitro: The effects of antibodies to IgM and .Journal of Immunology, , 120 (5 ) ,1465-1472

Ginsburg W.;Finkelman F.;Lipsky P. (01-01-1978. ) Circulating and mitogen-induced immunoglobulin-secreting cells in human peripheral blood: evaluation .Journal of Immunology, , 120 (1 ) ,33-39

Lipsky P.;Ginsburg W.;Finkelman F.;Ziff M. (01-01-1978. ) Control of human B lymphocyte responsiveness: enhanced suppressor T cell activity after in vitro inc .Journal of Immunology, , 120 (3 ) ,902-910

Edelson R.;Finkelman F.;Steinberg A.;Ahmed A.;Broder S.;Strong M.;Green I. (01-01-1978. ) Reactivity of lupus erythematosus antibodies with leukemic helper T cells.Journal of Investigative Dermatology, , 70 (1 ) ,42-44 More Information

Finkelman F.;Van Boxel J.;Asofsky R.;Paul W. (12-01-1976. ) Cell membrane IgD: demonstration of IgD on human lymphocytes by enzyme catalyzed iodination and comp .Journal of Immunology, , 116 (4 ) ,1173-1181

Shevach E.;Ben-Sasson S.;Finkelman F.;Paul W.;Green I. (06-01-1975. ) Mechanisms of action of genes controlling the immune response. Transplantation Proceedings, , 7 (2 ) ,141-147

Finkelman F.;Smith A.;Scher I.;Paul W. (01-01-1975. ) Abnormal ratio of membrane immunoglobulin classes in mice with an X-linked B-lymphocyte defect.Journal of Experimental Medicine, , 142 (5 ) ,1316-1321 More Information

Schwartz B.;Finkelman F.;Paul W.;Shevach E. (01-01-1975. ) Structural characteristics of guinea pig MHC antigens .Federation Proceedings, , 34 (3 ) ,

Shevach E.;Finkelman F.;Ben?Sasson S.;Green I.;Paul W. (01-01-1975. ) Ir GENES AND ANTIGEN RECOGNITION.Annals of the New York Academy of Sciences, , 249 (1 ) ,541-547 More Information

Eshleman, Emily M; Rice, Taylor; Potter, Crystal; Waddell, Amanda; Hashimoto-Hill, Seika; Woo, Vivienne; Field, Sydney; Engleman, Laura; Lim, Hee-Woong; Schumacher, Michael A; Frey, Mark R; Denson, Lee A; Finkelman, Fred D; Alenghat, Theresa (2024. ) Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity.Immunity, , 57 (2 ) ,319-332.e6 More Information

Li, Yapeng; Gao, Junfeng; Zhao, Dianzheng; Guan, Xiaoyu; Morris, Suzanne C; Finkelman, Fred D; Huang, Hua (2023. ) The Hdc GC box is critical for Hdc gene transcription and histamine-mediated anaphylaxis.The Journal of allergy and clinical immunology, , 152 (1 ) ,195-204.e3 More Information

Udoye, Christopher C; Rau, Christina N; Freye, Sarah M; Almeida, Larissa N; Vera-Cruz, Sarah; Othmer, Kai; Korkmaz, Rabia Ü; Clauder, Ann-Katrin; Lindemann, Timo; Niebuhr, Markus; Ott, Fabian; Kalies, Kathrin; Recke, Andreas; Busch, Hauke; Fähnrich, Anke; Finkelman, Fred D; Manz, Rudolf A (2022. ) B-cell receptor physical properties affect relative IgG1 and IgE responses in mouse egg allergy.Mucosal immunology, , 15 (6 ) ,1375-1388 More Information

Zhen, Yuxuan; McGaha, Tracy L; Finkelman, Fred D; Shao, Wen-Hai (2022. ) The Akt-mTORC1 pathway mediates Axl receptor tyrosine kinase-induced mesangial cell proliferation.Journal of leukocyte biology, , 111 (3 ) ,563-571 More Information

Morris, Suzanne C; Perkins, Charles; Potter, Crystal; Parsons, David; Schuman, Richard; Khodoun, Marat V; Samavedam, Unni; Strait, Richard; Finkelman, Fred D (2022. ) Optimizing drug inhibition of IgE-mediated anaphylaxis in mice.The Journal of allergy and clinical immunology, , 149 (2 ) ,671-684.e9 More Information

Khodoun, Marat V; Morris, Suzanne C; Shao, Wen-Hai; Potter, Crystal; Angerman, Elizabeth; Kiselev, Artem; Yarawsky, Alexander E; Herr, Andrew B; Klausz, Katja; Otte, Anna; Peipp, Matthias; Finkelman, Fred D (2021. ) Suppression of IgE-mediated anaphylaxis and food allergy with monovalent anti-FcεRIα mAbs.The Journal of allergy and clinical immunology, , 147 (5 ) ,1838-1854.e4 More Information

Farazuddin, Mohammad; Landers, Jeffrey J; Janczak, Katarzyna W; Lindsey, Hayley K; Finkelman, Fred D; Baker, James R; O'Konek, Jessica J (2021. ) Mucosal Nanoemulsion Allergy Vaccine Suppresses Alarmin Expression and Induces Bystander Suppression of Reactivity to Multiple Food Allergens.Frontiers in immunology, , 12 ,599296 More Information

Link, Christopher W M; Rau, Christina N; Udoye, Christopher C; Ragab, Mohab; Korkmaz, Rabia Ü; Comdühr, Sara; Clauder, Ann-Katrin; Lindemann, Timo; Frehse, Britta; Hofmann, Katharina; Almeida, Larissa N; Laumonnier, Yves; Beidaq, Asmaa El; Finkelman, Fred D; Manz, Rudolf A (2020. ) IL-2-Agonist-Induced IFN-γ Exacerbates Systemic Anaphylaxis in Food Allergen-Sensitized Mice.Frontiers in immunology, , 11 ,596772 More Information

Paranjape, Anuya; Haque, Tamara T; Kiwanuka, Kasalina N; Qayum, Amina Abdul; Barnstein, Brian O; Finkelman, Fred D; Nigrovic, Peter A; Ryan, John J (2020. ) The Fyn-Stat5 cascade is required for Fcγ receptor-mediated mast cell function.Cellular immunology, , 356 ,104134 More Information

Rathod, Sanjay; Ramsey, Manda; Finkelman, Fred D; Fernandez, Christian A (2020. ) Genetic inhibition of NFATC2 attenuates asparaginase hypersensitivity in mice.Blood advances, , 4 (18 ) ,4406-4416 More Information

Honors and Awards

1967 Phi Beta Kappa Queens College

1970 Alpha Omega Alpha Yale University School of Medicine

American Society of Clinical Investigation

American Association of Immunologists

American College of Rheumatology

American Association of Physicians

American Association for Allergy, Asthma, and Immunology

Fellow - American Association for the Advancement of Science

One of 100 most-cited immunologists

Arthritis Foundation "Arthritis Hero"

2009 AAAAI Jerry Dolovich Memorial Lectureship

Keywords

Vaccine,Cytokine,Immunity,Nematoda,Hybridoma,Mast Cell,Lymphocyte,Interleukin,B Lymphocyte,Superantigen,T Lymphocyte,Disease Model,Laboratory Rat,Epitope Mapping,Gene Expression,Immunomodulator,T Cell Receptor,Escherichia Coli,Interferon Gamma,Laboratory Mouse,Cellular Immunity,Chemical Kinetics,Transgenic Animal,Helminthic Antigen,Autoimmune Disorder,Immunocytochemistry,Monoclonal Antibody,Cell Differentiation,Protein Purification,Neutralizing Antibody,Cytotoxic T Lymphocyte,Microorganism Immunology,Host Organism Interaction,Polymerase Chain Reaction,Gastrointestinal Infection,Nonhuman Therapy Evaluation,Drug Design Synthesis Production,Enzyme Linked Immunosorbent Assay,Leukocyte Activation Transformation,High Performance Liquid Chromatography

Contact Information

Academic - Health Professions Building
3255 Eden Avenue
Cincinnati  Ohio, 45267-0563
Phone: (513) 558-4701
Fax: (513) 558-3799
fred.finkelman@uc.edu