Stephan Glasser

Stephan W Glasser

Adjunct Associate Professor

Medical Sciences Building

COM Medical Education - 0521

Publications

Peer Reviewed Publications

Glasser, Stephan W; Hagood, James S; Wong, Simon; Taype, Carmen A; Madala, Satish K; Hardie, William D (2016. )Mechanisms of Lung Fibrosis Resolution.The American journal of pathology, ,186 (5 ),1066-77

Glasser, Stephan W; Maxfield, Melissa D; Ruetschilling, Teah L; Akinbi, Henry T; Baatz, John E; Kitzmiller, Joseph A; Page, Kristen; Xu, Yan; Bao, Erik L; Korfhagen, Thomas R (2013. )Persistence of LPS-induced lung inflammation in surfactant protein-C-deficient mice.American journal of respiratory cell and molecular biology, ,49 (5 ),845-54

Glasser, Stephan W; Senft, Albert P; Maxfield, Melissa D; Ruetschilling, Teah L; Baatz, John E; Page, Kristen; Korfhagen, Thomas R (2013. )Genetic replacement of surfactant protein-C reduces respiratory syncytial virus induced lung injury.Respiratory research, ,14 ,19

Wortham, Brian W; Eppert, Bryan L; Motz, Greg T; Flury, Jennifer L; Orozco-Levi, Mauricio; Hoebe, Kasper; Panos, Ralph J; Maxfield, Melissa; Glasser, Stephan W; Senft, Albert P; Raulet, David H; Borchers, Michael T (2012. )NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease.Journal of immunology (Baltimore, Md. : 1950), ,188 (9 ),4468-75

Glasser, Stephan W; Senft, Albert P (2011. )Use of transgenic mouse models to understand the origins of familial pulmonary fibrosis.Current pharmaceutical biotechnology, ,12 (9 ),1447-54

Madala, Satish K; Maxfield, Melissa D; Davidson, Cynthia R; Schmidt, Stephanie M; Garry, Daniel; Ikegami, Machiko; Hardie, William D; Glasser, Stephan W (2011. )Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice.Pulmonary medicine, ,2011 ,653524

Glasser, Stephan W; Hardie, William D; Hagood, James S (2010. )Pathogenesis of Interstitial Lung Disease in Children and Adults.Pediatric allergy, immunology, and pulmonology, ,23 (1 ),9-14

Hardie, William D; Glasser, Stephan W; Hagood, James S (2009. )Emerging concepts in the pathogenesis of lung fibrosis.The American journal of pathology, ,175 (1 ),3-16

Glasser, Stephan W; Witt, Teah L; Senft, Albert P; Baatz, John E; Folger, Dusti; Maxfield, Melissa D; Akinbi, Henry T; Newton, Danforth A; Prows, Daniel R; Korfhagen, Thomas R (2009. )Surfactant protein C-deficient mice are susceptible to respiratory syncytial virus infection.American journal of physiology. Lung cellular and molecular physiology, ,297 (1 ),L64-72

Glasser, Stephan W; Senft, Albert P; Whitsett, Jeffrey A; Maxfield, Melissa D; Ross, Gary F; Richardson, Theresa R; Prows, Daniel R; Xu, Yan; Korfhagen, Thomas R (2008. )Macrophage dysfunction and susceptibility to pulmonary Pseudomonas aeruginosa infection in surfactant protein C-deficient mice.Journal of immunology (Baltimore, Md. : 1950), ,181 (1 ),621-8

Glasser, Stephan W; Nogee, Lawrence M (2006. )Genetically engineered mice in understanding the basis of neonatal lung disease.Seminars in perinatology, ,30 (6 ),341-9

Lawson, William E; Polosukhin, Vasiliy V; Stathopoulos, Georgios T; Zoia, Ornella; Han, Wei; Lane, Kirk B; Li, Bo; Donnelly, Edwin F; Holburn, George E; Lewis, Kenneth G; Collins, Robert D; Hull, William M; Glasser, Stephan W; Whitsett, Jeffrey A; Blackwell, Timothy S (2005. )Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin.The American journal of pathology, ,167 (5 ),1267-77

Glasser, Stephan W; Eszterhas, Susan K; Detmer, Emily A; Maxfield, Melissa D; Korfhagen, Thomas R (2005. )The murine SP-C promoter directs type II cell-specific expression in transgenic mice.American journal of physiology. Lung cellular and molecular physiology, ,288 (4 ),L625-32

Glasser, Stephan W; Detmer, Emily A; Ikegami, Machiko; Na, Cheng-Lun; Stahlman, Mildred T; Whitsett, Jeffrey A (2003. )Pneumonitis and emphysema in sp-C gene targeted mice.The Journal of biological chemistry, ,278 (16 ),14291-8

Liu, Cong; Glasser, Stephan W; Wan, Huajing; Whitsett, Jeffrey A (2002. )GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression.The Journal of biological chemistry, ,277 (6 ),4519-25

Ikegami, Machiko; Weaver, Timothy E; Conkright, Juliana J; Sly, Peter D; Ross, Gary F; Whitsett, Jeffrey A; Glasser, Stephan W (2002. )Deficiency of SP-B reveals protective role of SP-C during oxygen lung injury.Journal of applied physiology (Bethesda, Md. : 1985), ,92 (2 ),519-26

Whitsett, J A; Glasser, S W; Tichelaar, J W; Perl, A K; Clark, J C; Wert, S E (2001. )Transgenic models for study of lung morphogenesis and repair: Parker B. Francis lecture.Chest, ,120 (1 Suppl ),27S-30S

Glasser, S W; Burhans, M S; Korfhagen, T R; Na, C L; Sly, P D; Ross, G F; Ikegami, M; Whitsett, J A (2001. )Altered stability of pulmonary surfactant in SP-C-deficient mice.Proceedings of the National Academy of Sciences of the United States of America, ,98 (11 ),6366-71

Conkright, J J; Bridges, J P; Na, C L; Voorhout, W F; Trapnell, B; Glasser, S W; Weaver, T E (2001. )Secretion of surfactant protein C, an integral membrane protein, requires the N-terminal propeptide.The Journal of biological chemistry, ,276 (18 ),14658-64

Glasser, S W; Burhans, M S; Eszterhas, S K; Bruno, M D; Korfhagen, T R (2000. )Human SP-C gene sequences that confer lung epithelium-specific expression in transgenic mice.American journal of physiology. Lung cellular and molecular physiology, ,278 (5 ),L933-45

Whitsett, J A; Glasser, S W (1998. )Regulation of surfactant protein gene transcription.Biochimica et biophysica acta, ,1408 (2-3 ),303-11

Bachurski, C J; Kelly, S E; Glasser, S W; Currier, T A (1997. )Nuclear factor I family members regulate the transcription of surfactant protein-C.The Journal of biological chemistry, ,272 (52 ),32759-66

Hardie, W D; Kerlakian, C B; Bruno, M D; Huelsman, K M; Wert, S E; Glasser, S W; Whitsett, J A; Korfhagen, T R (1996. )Reversal of lung lesions in transgenic transforming growth factor alpha mice by expression of mutant epidermal growth factor receptor.American journal of respiratory cell and molecular biology, ,15 (4 ),499-508

Korfhagen, T R; Bruno, M D; Ross, G F; Huelsman, K M; Ikegami, M; Jobe, A H; Wert, S E; Stripp, B R; Morris, R E; Glasser, S W; Bachurski, C J; Iwamoto, H S; Whitsett, J A (1996. )Altered surfactant function and structure in SP-A gene targeted mice.Proceedings of the National Academy of Sciences of the United States of America, ,93 (18 ),9594-9

Kelly, S E; Bachurski, C J; Burhans, M S; Glasser, S W (1996. )Transcription of the lung-specific surfactant protein C gene is mediated by thyroid transcription factor 1.The Journal of biological chemistry, ,271 (12 ),6881-8

Bachurski, C J; Pryhuber, G S; Glasser, S W; Kelly, S E; Whitsett, J A (1995. )Tumor necrosis factor-alpha inhibits surfactant protein C gene transcription.The Journal of biological chemistry, ,270 (33 ),19402-7

Glasser, S W; Korfhagen, T R; Wert, S E; Whitsett, J A (1994. )Transgenic models for study of pulmonary development and disease.The American journal of physiology, ,267 (5 Pt 1 ),L489-97

Korfhagen, T R; Glasser, S W; Stripp, B R (1994. )Regulation of gene expression in the lung. Current opinion in pediatrics, ,6 (3 ),255-61

Korfhagen, T R; Swantz, R J; Wert, S E; McCarty, J M; Kerlakian, C B; Glasser, S W; Whitsett, J A (1994. )Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice.The Journal of clinical investigation, ,93 (4 ),1691-9

Baatz, J E; Bruno, M D; Ciraolo, P J; Glasser, S W; Stripp, B R; Smyth, K L; Korfhagen, T R (1994. )Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture.Proceedings of the National Academy of Sciences of the United States of America, ,91 (7 ),2547-51

Wert, S E; Glasser, S W; Korfhagen, T R; Whitsett, J A (1993. )Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice.Developmental biology, ,156 (2 ),426-43

Wispé, J R; Warner, B B; Clark, J C; Dey, C R; Neuman, J; Glasser, S W; Crapo, J D; Chang, L Y; Whitsett, J A (1992. )Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury. The Journal of biological chemistry, ,267 (33 ),23937-41

Korfhagen, T R; Bruno, M D; Glasser, S W; Ciraolo, P J; Whitsett, J A; Lattier, D L; Wikenheiser, K A; Clark, J C (1992. )Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity.The American journal of physiology, ,263 (5 Pt 1 ),L546-54

Moore, K J; D'Amore-Bruno, M A; Korfhagen, T R; Glasser, S W; Whitsett, J A; Jenkins, N A; Copeland, N G (1992. )Chromosomal localization of three pulmonary surfactant protein genes in the mouse.Genomics, ,12 (2 ),388-93

Glasser, S W; Korfhagen, T R; Wert, S E; Bruno, M D; McWilliams, K M; Vorbroker, D K; Whitsett, J A (1991. )Genetic element from human surfactant protein SP-C gene confers bronchiolar-alveolar cell specificity in transgenic mice.The American journal of physiology, ,261 (4 Pt 1 ),L349-56

Korfhagen, T R; Glasser, S W; Bruno, M D; McMahan, M J; Whitsett, J A (1991. )A portion of the human surfactant protein A (SP-A) gene locus consists of a pseudogene.American journal of respiratory cell and molecular biology, ,4 (5 ),463-9

Glasser, S W; Korfhagen, T R; Bruno, M D; Dey, C; Whitsett, J A (1990. )Structure and expression of the pulmonary surfactant protein SP-C gene in the mouse. The Journal of biological chemistry, ,265 (35 ),21986-91

Korfhagen, T R; Glasser, S W; Wert, S E; Bruno, M D; Daugherty, C C; McNeish, J D; Stock, J L; Potter, S S; Whitsett, J A (1990. )Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice.Proceedings of the National Academy of Sciences of the United States of America, ,87 (16 ),6122-6

Pilot-Matias, T J; Kister, S E; Fox, J L; Kropp, K; Glasser, S W; Whitsett, J A (1989. )Structure and organization of the gene encoding human pulmonary surfactant proteolipid SP-B.DNA (Mary Ann Liebert, Inc.), ,8 (2 ),75-86

Glasser, S W; Korfhagen, T R; Perme, C M; Pilot-Matias, T J; Kister, S E; Whitsett, J A (1988. )Two SP-C genes encoding human pulmonary surfactant proteolipid. The Journal of biological chemistry, ,263 (21 ),10326-31

Glasser, S W; Korfhagen, T R; Weaver, T E; Clark, J C; Pilot-Matias, T; Meuth, J; Fox, J L; Whitsett, J A (1988. )cDNA, deduced polypeptide structure and chromosomal assignment of human pulmonary surfactant proteolipid, SPL(pVal). The Journal of biological chemistry, ,263 (1 ),9-12

Whitsett, J A; Weaver, T E; Clark, J C; Sawtell, N; Glasser, S W; Korfhagen, T R; Hull, W M (1987. )Glucocorticoid enhances surfactant proteolipid Phe and pVal synthesis and RNA in fetal lung. The Journal of biological chemistry, ,262 (32 ),15618-23

Glasser, S W; Korfhagen, T R; Weaver, T; Pilot-Matias, T; Fox, J L; Whitsett, J A (1987. )cDNA and deduced amino acid sequence of human pulmonary surfactant-associated proteolipid SPL(Phe).Proceedings of the National Academy of Sciences of the United States of America, ,84 (12 ),4007-11