Publications
Peer Reviewed Publications
Glasser, Stephan W; Hagood, James S; Wong, Simon; Taype, Carmen A; Madala, Satish K; Hardie, William D (2016). Mechanisms of Lung Fibrosis Resolution. The American journal of pathology, 186 (5) , 1066-77More Information
Glasser, Stephan W; Maxfield, Melissa D; Ruetschilling, Teah L; Akinbi, Henry T; Baatz, John E; Kitzmiller, Joseph A; Page, Kristen; Xu, Yan; Bao, Erik L; Korfhagen, Thomas R (2013). Persistence of LPS-induced lung inflammation in surfactant protein-C-deficient mice. American journal of respiratory cell and molecular biology, 49 (5) , 845-54More Information
Glasser, Stephan W; Senft, Albert P; Maxfield, Melissa D; Ruetschilling, Teah L; Baatz, John E; Page, Kristen; Korfhagen, Thomas R (2013). Genetic replacement of surfactant protein-C reduces respiratory syncytial virus induced lung injury. Respiratory research, 14, 19More Information
Wortham, Brian W; Eppert, Bryan L; Motz, Greg T; Flury, Jennifer L; Orozco-Levi, Mauricio; Hoebe, Kasper; Panos, Ralph J; Maxfield, Melissa; Glasser, Stephan W; Senft, Albert P; Raulet, David H; Borchers, Michael T (2012). NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease. Journal of immunology (Baltimore, Md. : 1950), 188 (9) , 4468-75More Information
Glasser, Stephan W; Senft, Albert P (2011). Use of transgenic mouse models to understand the origins of familial pulmonary fibrosis. Current pharmaceutical biotechnology, 12 (9) , 1447-54More Information
Madala, Satish K; Maxfield, Melissa D; Davidson, Cynthia R; Schmidt, Stephanie M; Garry, Daniel; Ikegami, Machiko; Hardie, William D; Glasser, Stephan W (2011). Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice. Pulmonary medicine, 2011, 653524More Information
Glasser, Stephan W; Hardie, William D; Hagood, James S (2010). Pathogenesis of Interstitial Lung Disease in Children and Adults. Pediatric allergy, immunology, and pulmonology, 23 (1) , 9-14More Information
Hardie, William D; Glasser, Stephan W; Hagood, James S (2009). Emerging concepts in the pathogenesis of lung fibrosis. The American journal of pathology, 175 (1) , 3-16More Information
Glasser, Stephan W; Witt, Teah L; Senft, Albert P; Baatz, John E; Folger, Dusti; Maxfield, Melissa D; Akinbi, Henry T; Newton, Danforth A; Prows, Daniel R; Korfhagen, Thomas R (2009). Surfactant protein C-deficient mice are susceptible to respiratory syncytial virus infection. American journal of physiology. Lung cellular and molecular physiology, 297 (1) , L64-72More Information
Glasser, Stephan W; Senft, Albert P; Whitsett, Jeffrey A; Maxfield, Melissa D; Ross, Gary F; Richardson, Theresa R; Prows, Daniel R; Xu, Yan; Korfhagen, Thomas R (2008). Macrophage dysfunction and susceptibility to pulmonary Pseudomonas aeruginosa infection in surfactant protein C-deficient mice. Journal of immunology (Baltimore, Md. : 1950), 181 (1) , 621-8More Information
Glasser, Stephan W; Nogee, Lawrence M (2006). Genetically engineered mice in understanding the basis of neonatal lung disease. Seminars in perinatology, 30 (6) , 341-9More Information
Lawson, William E; Polosukhin, Vasiliy V; Stathopoulos, Georgios T; Zoia, Ornella; Han, Wei; Lane, Kirk B; Li, Bo; Donnelly, Edwin F; Holburn, George E; Lewis, Kenneth G; Collins, Robert D; Hull, William M; Glasser, Stephan W; Whitsett, Jeffrey A; Blackwell, Timothy S (2005). Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin. The American journal of pathology, 167 (5) , 1267-77More Information
Glasser, Stephan W; Eszterhas, Susan K; Detmer, Emily A; Maxfield, Melissa D; Korfhagen, Thomas R (2005). The murine SP-C promoter directs type II cell-specific expression in transgenic mice. American journal of physiology. Lung cellular and molecular physiology, 288 (4) , L625-32More Information
Glasser, Stephan W; Detmer, Emily A; Ikegami, Machiko; Na, Cheng-Lun; Stahlman, Mildred T; Whitsett, Jeffrey A (2003). Pneumonitis and emphysema in sp-C gene targeted mice. The Journal of biological chemistry, 278 (16) , 14291-8More Information
Liu, Cong; Glasser, Stephan W; Wan, Huajing; Whitsett, Jeffrey A (2002). GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression. The Journal of biological chemistry, 277 (6) , 4519-25More Information
Ikegami, Machiko; Weaver, Timothy E; Conkright, Juliana J; Sly, Peter D; Ross, Gary F; Whitsett, Jeffrey A; Glasser, Stephan W (2002). Deficiency of SP-B reveals protective role of SP-C during oxygen lung injury. Journal of applied physiology (Bethesda, Md. : 1985), 92 (2) , 519-26More Information
Whitsett, J A; Glasser, S W; Tichelaar, J W; Perl, A K; Clark, J C; Wert, S E (2001). Transgenic models for study of lung morphogenesis and repair: Parker B. Francis lecture. Chest, 120 (1 Suppl) , 27S-30SMore Information
Glasser, S W; Burhans, M S; Korfhagen, T R; Na, C L; Sly, P D; Ross, G F; Ikegami, M; Whitsett, J A (2001). Altered stability of pulmonary surfactant in SP-C-deficient mice. Proceedings of the National Academy of Sciences of the United States of America, 98 (11) , 6366-71More Information
Conkright, J J; Bridges, J P; Na, C L; Voorhout, W F; Trapnell, B; Glasser, S W; Weaver, T E (2001). Secretion of surfactant protein C, an integral membrane protein, requires the N-terminal propeptide. The Journal of biological chemistry, 276 (18) , 14658-64More Information
Glasser, S W; Burhans, M S; Eszterhas, S K; Bruno, M D; Korfhagen, T R (2000). Human SP-C gene sequences that confer lung epithelium-specific expression in transgenic mice. American journal of physiology. Lung cellular and molecular physiology, 278 (5) , L933-45More Information
Whitsett, J A; Glasser, S W (1998). Regulation of surfactant protein gene transcription. Biochimica et biophysica acta, 1408 (2-3) , 303-11More Information
Bachurski, C J; Kelly, S E; Glasser, S W; Currier, T A (1997). Nuclear factor I family members regulate the transcription of surfactant protein-C. The Journal of biological chemistry, 272 (52) , 32759-66More Information
Hardie, W D; Kerlakian, C B; Bruno, M D; Huelsman, K M; Wert, S E; Glasser, S W; Whitsett, J A; Korfhagen, T R (1996). Reversal of lung lesions in transgenic transforming growth factor alpha mice by expression of mutant epidermal growth factor receptor. American journal of respiratory cell and molecular biology, 15 (4) , 499-508More Information
Korfhagen, T R; Bruno, M D; Ross, G F; Huelsman, K M; Ikegami, M; Jobe, A H; Wert, S E; Stripp, B R; Morris, R E; Glasser, S W; Bachurski, C J; Iwamoto, H S; Whitsett, J A (1996). Altered surfactant function and structure in SP-A gene targeted mice. Proceedings of the National Academy of Sciences of the United States of America, 93 (18) , 9594-9More Information
Kelly, S E; Bachurski, C J; Burhans, M S; Glasser, S W (1996). Transcription of the lung-specific surfactant protein C gene is mediated by thyroid transcription factor 1. The Journal of biological chemistry, 271 (12) , 6881-8More Information
Bachurski, C J; Pryhuber, G S; Glasser, S W; Kelly, S E; Whitsett, J A (1995). Tumor necrosis factor-alpha inhibits surfactant protein C gene transcription. The Journal of biological chemistry, 270 (33) , 19402-7More Information
Glasser, S W; Korfhagen, T R; Wert, S E; Whitsett, J A (1994). Transgenic models for study of pulmonary development and disease. The American journal of physiology, 267 (5 Pt 1) , L489-97More Information
Korfhagen, T R; Glasser, S W; Stripp, B R (1994). Regulation of gene expression in the lung. Current opinion in pediatrics, 6 (3) , 255-61
Korfhagen, T R; Swantz, R J; Wert, S E; McCarty, J M; Kerlakian, C B; Glasser, S W; Whitsett, J A (1994). Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice. The Journal of clinical investigation, 93 (4) , 1691-9More Information
Baatz, J E; Bruno, M D; Ciraolo, P J; Glasser, S W; Stripp, B R; Smyth, K L; Korfhagen, T R (1994). Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture. Proceedings of the National Academy of Sciences of the United States of America, 91 (7) , 2547-51More Information
Wert, S E; Glasser, S W; Korfhagen, T R; Whitsett, J A (1993). Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice. Developmental biology, 156 (2) , 426-43More Information
Wispé, J R; Warner, B B; Clark, J C; Dey, C R; Neuman, J; Glasser, S W; Crapo, J D; Chang, L Y; Whitsett, J A (1992). Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury. The Journal of biological chemistry, 267 (33) , 23937-41
Korfhagen, T R; Bruno, M D; Glasser, S W; Ciraolo, P J; Whitsett, J A; Lattier, D L; Wikenheiser, K A; Clark, J C (1992). Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity. The American journal of physiology, 263 (5 Pt 1) , L546-54More Information
Moore, K J; D'Amore-Bruno, M A; Korfhagen, T R; Glasser, S W; Whitsett, J A; Jenkins, N A; Copeland, N G (1992). Chromosomal localization of three pulmonary surfactant protein genes in the mouse. Genomics, 12 (2) , 388-93More Information
Glasser, S W; Korfhagen, T R; Wert, S E; Bruno, M D; McWilliams, K M; Vorbroker, D K; Whitsett, J A (1991). Genetic element from human surfactant protein SP-C gene confers bronchiolar-alveolar cell specificity in transgenic mice. The American journal of physiology, 261 (4 Pt 1) , L349-56More Information
Korfhagen, T R; Glasser, S W; Bruno, M D; McMahan, M J; Whitsett, J A (1991). A portion of the human surfactant protein A (SP-A) gene locus consists of a pseudogene. American journal of respiratory cell and molecular biology, 4 (5) , 463-9More Information
Glasser, S W; Korfhagen, T R; Bruno, M D; Dey, C; Whitsett, J A (1990). Structure and expression of the pulmonary surfactant protein SP-C gene in the mouse. The Journal of biological chemistry, 265 (35) , 21986-91
Korfhagen, T R; Glasser, S W; Wert, S E; Bruno, M D; Daugherty, C C; McNeish, J D; Stock, J L; Potter, S S; Whitsett, J A (1990). Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America, 87 (16) , 6122-6More Information
Pilot-Matias, T J; Kister, S E; Fox, J L; Kropp, K; Glasser, S W; Whitsett, J A (1989). Structure and organization of the gene encoding human pulmonary surfactant proteolipid SP-B. DNA (Mary Ann Liebert, Inc.), 8 (2) , 75-86More Information
Glasser, S W; Korfhagen, T R; Perme, C M; Pilot-Matias, T J; Kister, S E; Whitsett, J A (1988). Two SP-C genes encoding human pulmonary surfactant proteolipid. The Journal of biological chemistry, 263 (21) , 10326-31
Glasser, S W; Korfhagen, T R; Weaver, T E; Clark, J C; Pilot-Matias, T; Meuth, J; Fox, J L; Whitsett, J A (1988). cDNA, deduced polypeptide structure and chromosomal assignment of human pulmonary surfactant proteolipid, SPL(pVal). The Journal of biological chemistry, 263 (1) , 9-12
Whitsett, J A; Weaver, T E; Clark, J C; Sawtell, N; Glasser, S W; Korfhagen, T R; Hull, W M (1987). Glucocorticoid enhances surfactant proteolipid Phe and pVal synthesis and RNA in fetal lung. The Journal of biological chemistry, 262 (32) , 15618-23
Glasser, S W; Korfhagen, T R; Weaver, T; Pilot-Matias, T; Fox, J L; Whitsett, J A (1987). cDNA and deduced amino acid sequence of human pulmonary surfactant-associated proteolipid SPL(Phe). Proceedings of the National Academy of Sciences of the United States of America, 84 (12) , 4007-11More Information