Stephan Glasser

Stephan W Glasser

Adjunct Associate Professor

Medical Sciences Building

COM Medical Education - 0552

Publications

Peer Reviewed Publications

Glasser, Stephan W; Hagood, James S; Wong, Simon; Taype, Carmen A; Madala, Satish K; Hardie, William D (2016. ) Mechanisms of Lung Fibrosis Resolution.The American journal of pathology, , 186 (5 ) ,1066-77

Glasser, Stephan W; Maxfield, Melissa D; Ruetschilling, Teah L; Akinbi, Henry T; Baatz, John E; Kitzmiller, Joseph A; Page, Kristen; Xu, Yan; Bao, Erik L; Korfhagen, Thomas R (2013. ) Persistence of LPS-induced lung inflammation in surfactant protein-C-deficient mice.American journal of respiratory cell and molecular biology, , 49 (5 ) ,845-54

Glasser, Stephan W; Senft, Albert P; Maxfield, Melissa D; Ruetschilling, Teah L; Baatz, John E; Page, Kristen; Korfhagen, Thomas R (2013. ) Genetic replacement of surfactant protein-C reduces respiratory syncytial virus induced lung injury.Respiratory research, , 14 ,19

Wortham, Brian W; Eppert, Bryan L; Motz, Greg T; Flury, Jennifer L; Orozco-Levi, Mauricio; Hoebe, Kasper; Panos, Ralph J; Maxfield, Melissa; Glasser, Stephan W; Senft, Albert P; Raulet, David H; Borchers, Michael T (2012. ) NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease.Journal of immunology (Baltimore, Md. : 1950), , 188 (9 ) ,4468-75

Glasser, Stephan W; Senft, Albert P (2011. ) Use of transgenic mouse models to understand the origins of familial pulmonary fibrosis.Current pharmaceutical biotechnology, , 12 (9 ) ,1447-54

Madala, Satish K; Maxfield, Melissa D; Davidson, Cynthia R; Schmidt, Stephanie M; Garry, Daniel; Ikegami, Machiko; Hardie, William D; Glasser, Stephan W (2011. ) Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice.Pulmonary medicine, , 2011 ,653524

Glasser, Stephan W; Hardie, William D; Hagood, James S (2010. ) Pathogenesis of Interstitial Lung Disease in Children and Adults.Pediatric allergy, immunology, and pulmonology, , 23 (1 ) ,9-14

Hardie, William D; Glasser, Stephan W; Hagood, James S (2009. ) Emerging concepts in the pathogenesis of lung fibrosis.The American journal of pathology, , 175 (1 ) ,3-16

Glasser, Stephan W; Witt, Teah L; Senft, Albert P; Baatz, John E; Folger, Dusti; Maxfield, Melissa D; Akinbi, Henry T; Newton, Danforth A; Prows, Daniel R; Korfhagen, Thomas R (2009. ) Surfactant protein C-deficient mice are susceptible to respiratory syncytial virus infection.American journal of physiology. Lung cellular and molecular physiology, , 297 (1 ) ,L64-72

Glasser, Stephan W; Senft, Albert P; Whitsett, Jeffrey A; Maxfield, Melissa D; Ross, Gary F; Richardson, Theresa R; Prows, Daniel R; Xu, Yan; Korfhagen, Thomas R (2008. ) Macrophage dysfunction and susceptibility to pulmonary Pseudomonas aeruginosa infection in surfactant protein C-deficient mice.Journal of immunology (Baltimore, Md. : 1950), , 181 (1 ) ,621-8

Glasser, Stephan W; Nogee, Lawrence M (2006. ) Genetically engineered mice in understanding the basis of neonatal lung disease.Seminars in perinatology, , 30 (6 ) ,341-9

Lawson, William E; Polosukhin, Vasiliy V; Stathopoulos, Georgios T; Zoia, Ornella; Han, Wei; Lane, Kirk B; Li, Bo; Donnelly, Edwin F; Holburn, George E; Lewis, Kenneth G; Collins, Robert D; Hull, William M; Glasser, Stephan W; Whitsett, Jeffrey A; Blackwell, Timothy S (2005. ) Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin.The American journal of pathology, , 167 (5 ) ,1267-77

Glasser, Stephan W; Eszterhas, Susan K; Detmer, Emily A; Maxfield, Melissa D; Korfhagen, Thomas R (2005. ) The murine SP-C promoter directs type II cell-specific expression in transgenic mice.American journal of physiology. Lung cellular and molecular physiology, , 288 (4 ) ,L625-32

Glasser, Stephan W; Detmer, Emily A; Ikegami, Machiko; Na, Cheng-Lun; Stahlman, Mildred T; Whitsett, Jeffrey A (2003. ) Pneumonitis and emphysema in sp-C gene targeted mice.The Journal of biological chemistry, , 278 (16 ) ,14291-8

Liu, Cong; Glasser, Stephan W; Wan, Huajing; Whitsett, Jeffrey A (2002. ) GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression.The Journal of biological chemistry, , 277 (6 ) ,4519-25

Ikegami, Machiko; Weaver, Timothy E; Conkright, Juliana J; Sly, Peter D; Ross, Gary F; Whitsett, Jeffrey A; Glasser, Stephan W (2002. ) Deficiency of SP-B reveals protective role of SP-C during oxygen lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , 92 (2 ) ,519-26

Whitsett, J A; Glasser, S W; Tichelaar, J W; Perl, A K; Clark, J C; Wert, S E (2001. ) Transgenic models for study of lung morphogenesis and repair: Parker B. Francis lecture.Chest, , 120 (1 Suppl ) ,27S-30S

Glasser, S W; Burhans, M S; Korfhagen, T R; Na, C L; Sly, P D; Ross, G F; Ikegami, M; Whitsett, J A (2001. ) Altered stability of pulmonary surfactant in SP-C-deficient mice.Proceedings of the National Academy of Sciences of the United States of America, , 98 (11 ) ,6366-71

Conkright, J J; Bridges, J P; Na, C L; Voorhout, W F; Trapnell, B; Glasser, S W; Weaver, T E (2001. ) Secretion of surfactant protein C, an integral membrane protein, requires the N-terminal propeptide.The Journal of biological chemistry, , 276 (18 ) ,14658-64

Glasser, S W; Burhans, M S; Eszterhas, S K; Bruno, M D; Korfhagen, T R (2000. ) Human SP-C gene sequences that confer lung epithelium-specific expression in transgenic mice.American journal of physiology. Lung cellular and molecular physiology, , 278 (5 ) ,L933-45

Whitsett, J A; Glasser, S W (1998. ) Regulation of surfactant protein gene transcription.Biochimica et biophysica acta, , 1408 (2-3 ) ,303-11

Bachurski, C J; Kelly, S E; Glasser, S W; Currier, T A (1997. ) Nuclear factor I family members regulate the transcription of surfactant protein-C.The Journal of biological chemistry, , 272 (52 ) ,32759-66

Hardie, W D; Kerlakian, C B; Bruno, M D; Huelsman, K M; Wert, S E; Glasser, S W; Whitsett, J A; Korfhagen, T R (1996. ) Reversal of lung lesions in transgenic transforming growth factor alpha mice by expression of mutant epidermal growth factor receptor.American journal of respiratory cell and molecular biology, , 15 (4 ) ,499-508

Korfhagen, T R; Bruno, M D; Ross, G F; Huelsman, K M; Ikegami, M; Jobe, A H; Wert, S E; Stripp, B R; Morris, R E; Glasser, S W; Bachurski, C J; Iwamoto, H S; Whitsett, J A (1996. ) Altered surfactant function and structure in SP-A gene targeted mice.Proceedings of the National Academy of Sciences of the United States of America, , 93 (18 ) ,9594-9

Kelly, S E; Bachurski, C J; Burhans, M S; Glasser, S W (1996. ) Transcription of the lung-specific surfactant protein C gene is mediated by thyroid transcription factor 1.The Journal of biological chemistry, , 271 (12 ) ,6881-8

Bachurski, C J; Pryhuber, G S; Glasser, S W; Kelly, S E; Whitsett, J A (1995. ) Tumor necrosis factor-alpha inhibits surfactant protein C gene transcription.The Journal of biological chemistry, , 270 (33 ) ,19402-7

Glasser, S W; Korfhagen, T R; Wert, S E; Whitsett, J A (1994. ) Transgenic models for study of pulmonary development and disease.The American journal of physiology, , 267 (5 Pt 1 ) ,L489-97

Korfhagen, T R; Glasser, S W; Stripp, B R (1994. ) Regulation of gene expression in the lung. Current opinion in pediatrics, , 6 (3 ) ,255-61

Korfhagen, T R; Swantz, R J; Wert, S E; McCarty, J M; Kerlakian, C B; Glasser, S W; Whitsett, J A (1994. ) Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice.The Journal of clinical investigation, , 93 (4 ) ,1691-9

Baatz, J E; Bruno, M D; Ciraolo, P J; Glasser, S W; Stripp, B R; Smyth, K L; Korfhagen, T R (1994. ) Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture.Proceedings of the National Academy of Sciences of the United States of America, , 91 (7 ) ,2547-51

Wert, S E; Glasser, S W; Korfhagen, T R; Whitsett, J A (1993. ) Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice.Developmental biology, , 156 (2 ) ,426-43

Wispé, J R; Warner, B B; Clark, J C; Dey, C R; Neuman, J; Glasser, S W; Crapo, J D; Chang, L Y; Whitsett, J A (1992. ) Human Mn-superoxide dismutase in pulmonary epithelial cells of transgenic mice confers protection from oxygen injury. The Journal of biological chemistry, , 267 (33 ) ,23937-41

Korfhagen, T R; Bruno, M D; Glasser, S W; Ciraolo, P J; Whitsett, J A; Lattier, D L; Wikenheiser, K A; Clark, J C (1992. ) Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity.The American journal of physiology, , 263 (5 Pt 1 ) ,L546-54

Moore, K J; D'Amore-Bruno, M A; Korfhagen, T R; Glasser, S W; Whitsett, J A; Jenkins, N A; Copeland, N G (1992. ) Chromosomal localization of three pulmonary surfactant protein genes in the mouse.Genomics, , 12 (2 ) ,388-93

Glasser, S W; Korfhagen, T R; Wert, S E; Bruno, M D; McWilliams, K M; Vorbroker, D K; Whitsett, J A (1991. ) Genetic element from human surfactant protein SP-C gene confers bronchiolar-alveolar cell specificity in transgenic mice.The American journal of physiology, , 261 (4 Pt 1 ) ,L349-56

Korfhagen, T R; Glasser, S W; Bruno, M D; McMahan, M J; Whitsett, J A (1991. ) A portion of the human surfactant protein A (SP-A) gene locus consists of a pseudogene.American journal of respiratory cell and molecular biology, , 4 (5 ) ,463-9

Glasser, S W; Korfhagen, T R; Bruno, M D; Dey, C; Whitsett, J A (1990. ) Structure and expression of the pulmonary surfactant protein SP-C gene in the mouse. The Journal of biological chemistry, , 265 (35 ) ,21986-91

Korfhagen, T R; Glasser, S W; Wert, S E; Bruno, M D; Daugherty, C C; McNeish, J D; Stock, J L; Potter, S S; Whitsett, J A (1990. ) Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice.Proceedings of the National Academy of Sciences of the United States of America, , 87 (16 ) ,6122-6

Pilot-Matias, T J; Kister, S E; Fox, J L; Kropp, K; Glasser, S W; Whitsett, J A (1989. ) Structure and organization of the gene encoding human pulmonary surfactant proteolipid SP-B.DNA (Mary Ann Liebert, Inc.), , 8 (2 ) ,75-86

Glasser, S W; Korfhagen, T R; Perme, C M; Pilot-Matias, T J; Kister, S E; Whitsett, J A (1988. ) Two SP-C genes encoding human pulmonary surfactant proteolipid. The Journal of biological chemistry, , 263 (21 ) ,10326-31

Glasser, S W; Korfhagen, T R; Weaver, T E; Clark, J C; Pilot-Matias, T; Meuth, J; Fox, J L; Whitsett, J A (1988. ) cDNA, deduced polypeptide structure and chromosomal assignment of human pulmonary surfactant proteolipid, SPL(pVal). The Journal of biological chemistry, , 263 (1 ) ,9-12

Whitsett, J A; Weaver, T E; Clark, J C; Sawtell, N; Glasser, S W; Korfhagen, T R; Hull, W M (1987. ) Glucocorticoid enhances surfactant proteolipid Phe and pVal synthesis and RNA in fetal lung. The Journal of biological chemistry, , 262 (32 ) ,15618-23

Glasser, S W; Korfhagen, T R; Weaver, T; Pilot-Matias, T; Fox, J L; Whitsett, J A (1987. ) cDNA and deduced amino acid sequence of human pulmonary surfactant-associated proteolipid SPL(Phe).Proceedings of the National Academy of Sciences of the United States of America, , 84 (12 ) ,4007-11