Amit Govil

Amit Govil

Professor of Clinical Geo

Medical Sciences Building

6213A

COM IM Nephrology Division - 0585

Medical Sciences Building
Room 6213A
Cincinnati, 45267

Education

Medical Degree, Maulana Azad Medical College 1992

Residency, G.B. Pant Hospital 1995 (Medicine)

Residency, Maulana Azad Medical College 1996 (ENT)

Residency, Downstate Medical Center, Kings County Medical Center and VA 1999 (Internal Medicine)

Fellowship, University of Cincinnati Medical Center 2001 (Nephrology)

Fellowship, Oregon Health & Science University 2006 (Transplant Medicine)

Positions and Work Experience

2001 -2005 Community Nephrologist, Appalachian Regional Hospital Medical Center, Hazard, KY

2001 -2005 Assistant Professor (voluntary Part-time), East Kentucky Family Practice Residency Program, Hazard, KY

2006 -To Present Assistant Professor of Medicine, Transplant Medicine, Division of Nephrology and Hypertension, University of Cincinnati Medical Center, Cincinnati, OH

Research and Practice Interests

Medical Management of Kidney and Kidney-Pancreas Transplant Patients Along with Immunosupression Needs, Kidney-Pancreas Outcomes, Transplant Glomerulopathy, De-Sensitization of Sensitized Patients

Clinical Focus

Nephrology

Specialities

Internal Medicine

Nephrology

Certifications

American Board of Internal Medicine (Nephrology)

11/07/2001

Research Support

Novartis CAEB071A2207 A 12 Month Open Label, Randomized, Multicenter, Sequential Cohort, Dose Finding Study to Evaluate the Efficacy, Safety and Tolerability of Oral AEB071 vs. Tacrolimus in Combination with Myfortic, Simulect and Corticosteroids in de novo Adult Renal Transplant Recipients

Astellas 20-04-003 A Phase IV, Randomized, Open-Label, Comparative, Multi-Center Study to Assess the Safety and Efficacy of Induction Agents Alemtuzumab (Campath 1H), Basiliximab (Simulect) or Rabbit Anti-Thymocyte Globulin

Publications

Published Abstracts

Govil A, Peddi VR, First MR, et al (2000. ) Sirolimus substitution for calcineurin-inhibitors in renal allograft recipients with calcineurin-inhibitor nephrotoxicity .[Abstract]AM J Transplant, Suppl 1 ,247

Pitman S, Govil A, Roy-Chaudhury P, et al (2001. ) Alternative medicine use in dialysis patients: potential for good and bad! .[Abstract]J Am Soc Nephrol, 12 ,343A

Govil A, Peddi VR, First MR, et al (2001. ) Sirolimus substitution for calcineurin-inhibitors in renal allograft recipients with nephrotoxicity .[Abstract]J Am Soc Nephrol, 12 ,891A

Peddi VR, Govil A, First MR (2002. ) Long-term follow-up of sirolimus substitution for calcineurin-inhibitors in renal allograft recipients with nephrotoxicity .[Abstract]J Am Soc Nephrol, 13 ,184A

Roy-Chaudhury P, Govil A, Cavallo T, et al (2002. ) C4d deposition in chronic allograft dysfunction .[Abstract]J Am Soc Nephrol, 13 ,558A

Peer Reviewed Publications

Duncan H, Pittman S, Govil A, Roy-Chaudhury P, et al (2007. ) Alternative medicine use in dialysis patients: potential for good and bad! .Nephron Clin Pract, , 1005 (3 ) ,c108 -c113

Everly M, Everly J, Govil A, Woodle ES, et al (12-27-2008. ) Bortezomib provides effective therapy for antibody- and cell0mediated acute rejection .Transplantation, , 86 (12 ) ,1754 -1761

Everly M, Everly J, Govil A, Woodle ES, et al (03-16-2009. ) Reducing de novo donor-specific antibody levels during acute rejection diminishes renal allograft loss .Am J Transplant, , 9 (5 ) ,1063 -1071

Everly M, Everly J, Govil A, Woodle ES, et al (01-2009. ) Proteasome inhibition reduces donor-specific antibody levels .Transplant Proc., , 41 (1 ) ,105 -107

Walsh RC, Govil A, Woodle ES, et al (02-15-2010. ) Proteasome inhibitor-based primary therapy for antibody-mediated renal allograft rejection .Transplantation, , 89 (3 ) ,277 -284

Govil A, Woodle ES, Roy-Chaudhury PR, et al Influence of donor specific antibodies on the pattern of C3d disposition in renal allografts .

Walsh RC, Govil A, Woodle ES, et al (06-15-2011. ) Early and late acute antibody-mediated rejection differ immunoligically and in response to proteasome inhibition .Transplantation, , 91 (11 ) ,1218 -1226

Dao, Ann; Cuffy, Madison; Kaiser, Tiffany E; Loethen, Ashley; Cafardi, John; Luckett, Keith; Rike, Adele Helen; Cardi, Michael; Alloway, Rita R; Govil, Amit; Diwan, Tayyab; Sherman, Kenneth E; Shah, Shimul A; Woodle, Ervin Steve (2019. ) Use of HCV Ab+/NAT- donors in HCV naïve renal transplant recipients to expand the kidney donor pool.Clinical transplantation, , 33 (7 ) ,e13598

Cheung, Albert Y; Patel, Sunny; Kurji, Khaliq H; Sarnicola, Enrica; Eslani, Medi; Govil, Amit; Holland, Edward J (2019. ) Ocular Surface Stem Cell Transplantation for Treatment of Keratitis-Ichthyosis-Deafness Syndrome.Cornea, , 38 (1 ) ,123-126

Cheung, Albert Y; Sarnicola, Enrica; Eslani, Medi; Kurji, Khaliq H; Genereux, Brad M; Govil, Amit; Holland, Edward J (2018. ) Infectious Keratitis After Ocular Surface Stem Cell Transplantation.Cornea, , 37 (11 ) ,1395-1399

Cheung, Albert Y; Sarnicola, Enrica; Kurji, Khaliq H; Govil, Amit; Mogilishetty, Gautham; Eslani, Medi; Wright, Elizabeth; Brailey, Paul; Holland, Edward J (2018. ) Cincinnati Protocol for Preoperative Screening and Donor Selection for Ocular Surface Stem Cell Transplantation.Cornea, , 37 (9 ) ,1192-1197

Cheung, Albert Y; Genereux, Brad M; Dautremont, Brittney; Govil, Amit; Holland, Edward J (2018. ) Surgical management of severe ocular surface injury due to Roman candle explosion accidents.The ocular surface, , 16 (3 ) ,294-300

Cheung, Albert Y; Genereux, Brad M; Auteri, Nicholas J; Sarnicola, Enrica; Govil, Amit; Holland, Edward J (2018. ) Conjunctival-limbal allografts in graft-versus-host disease using same HLA-identical bone marrow transplantation donor.Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, , 53 (3 ) ,e120-e122

Kamal, Mahwash; Govil, Amit; Anand, Manish; Abu Jawdeh, Bassam G; Shah, Silvi (2018. ) Severe BK polyomavirus-induced hemorrhagic cystitis in a kidney transplant recipient with the absence of renal allograft involvement.Transplant infectious disease : an official journal of the Transplantation Society, , 20 (1 ) ,

Abu Jawdeh, Bassam G; Woodle, Ervin Steve; Leino, Abbie D; Brailey, Paul; Tremblay, Simon; Dorst, Tonya; Abdallah, Mouhamad H; Govil, Amit; Byczkowski, Daniel; Misra, Hemant; Abuchowski, Abraham; Alloway, Rita R (2018. ) A phase Ib, open-label, single arm study to assess the safety, pharmacokinetics, and impact on humoral sensitization of SANGUINATE infusion in patients with end-stage renal disease.Clinical transplantation, , 32 (1 ) ,

Movahedan, Asadolah; Cheung, Albert Y; Eslani, Medi; Mogilishetty, Gautham; Govil, Amit; Holland, Edward J (2017. ) Long-term Outcomes of Ocular Surface Stem Cell Allograft Transplantation.American journal of ophthalmology, , 184 ,97-107

Cheung, Albert Y; Sarnicola, Enrica; Govil, Amit; Holland, Edward J (2017. ) Combined Conjunctival Limbal Autografts and Living-Related Conjunctival Limbal Allografts for Severe Unilateral Ocular Surface Failure.Cornea, , 36 (12 ) ,1570-1575

Kamal, M; Apewokin, S; Anand, M; Abu Jawdeh, B G; Govil, A; Sheikh, M M; Shah, S (2017. ) Late-Onset Allograft Aspergillosis in an HIV-Positive Renal Transplant Recipient: A Case Report.Transplantation proceedings, , 49 (7 ) ,1570-1573

Cheung, Albert Y; Govil, Amit; Friedstrom, Scott R; Holland, Edward J (2017. ) Probable Donor-Derived Cytomegalovirus Disease After Keratolimbal Allograft Transplantation.Cornea, , 36 (8 ) ,1006-1008

Abu Jawdeh, Bassam G; Govil, Amit (2017. ) Acute Kidney Injury in Transplant Setting: Differential Diagnosis and Impact on Health and Health Care.Advances in chronic kidney disease, , 24 (4 ) ,228-232

Dedhia, P; Govil, A; Mogilishetty, G; Alloway, R R; Woodle, E S; Abu Jawdeh, B G Eculizumab and Belatacept for De Novo Atypical Hemolytic Uremic Syndrome Associated With CFHR3-CFHR1 Deletion in a Kidney Transplant Recipient: A Case Report.Transplantation proceedings, , 49 (1 ) ,188-192

Krisl, Jill C; Alloway, Rita R; Shield, Adele Rike; Govil, Amit; Mogilishetty, Gautham; Cardi, Michael; Diwan, Tayyab; Abu Jawdeh, Bassam G; Girnita, Alin; Witte, David; Woodle, E Steve (2015. ) Acute Rejection Clinically Defined Phenotypes Correlate With Long-term Renal Allograft Survival.Transplantation, , 99 (10 ) ,2167-73

Mittal, T; Dedhia, P; Roy-Chaudhury, P; Abu Jawdeh, B G; Mogilishetty, G; Cuffy, M C; Alloway, R R; Woodle, E S; Govil, A (2015. ) Complete Remission of Post-transplantation Recurrence of Focal Segmental Glomerulosclerosis With the Use of Adrenocorticotrophic Hormone Gel: Case Report.Transplantation proceedings, , 47 (7 ) ,2219-22

Freeman, C M; Woodle, E S; Shi, J; Alexander, J W; Leggett, P L; Shah, S A; Paterno, F; Cuffy, M C; Govil, A; Mogilishetty, G; Alloway, R R; Hanseman, D; Cardi, M; Diwan, T S (2015. ) Addressing morbid obesity as a barrier to renal transplantation with laparoscopic sleeve gastrectomy.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, , 15 (5 ) ,1360-8

Woodle, E S; Shields, A R; Ejaz, N S; Sadaka, B; Girnita, A; Walsh, R C; Alloway, R R; Brailey, P; Cardi, M A; Abu Jawdeh, B G; Roy-Chaudhury, P; Govil, A; Mogilishetty, G (2015. ) Prospective iterative trial of proteasome inhibitor-based desensitization.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, , 15 (1 ) ,101-18

Walsh, R Carlin; Brailey, Paul; Girnita, Alin; Alloway, Rita R; Shields, Adele Rike; Wall, Garth E; Sadaka, Basma H; Cardi, Michael; Tevar, Amit; Govil, Amit; Mogilishetty, Gautham; Roy-Chaudhury, Prabir; Woodle, E Steve (2011. ) Early and late acute antibody-mediated rejection differ immunologically and in response to proteasome inhibition.Transplantation, , 91 (11 ) ,1218-26

Walsh, R Carlin; Everly, Jason J; Brailey, Paul; Rike, Adele H; Arend, Lois J; Mogilishetty, Gautham; Govil, Amit; Roy-Chaudhury, Prabir; Alloway, Rita R; Woodle, E Steve (2010. ) Proteasome inhibitor-based primary therapy for antibody-mediated renal allograft rejection.Transplantation, , 89 (3 ) ,277-84

Everly, M J; Everly, J J; Arend, L J; Brailey, P; Susskind, B; Govil, A; Rike, A; Roy-Chaudhury, P; Mogilishetty, G; Alloway, R R; Tevar, A; Woodle, E S (2009. ) Reducing de novo donor-specific antibody levels during acute rejection diminishes renal allograft loss.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, , 9 (5 ) ,1063-71

Govil, Amit; Walsh, R Carlin; Tevar, Amit; Alloway, Rita; Roy-Chaudhury, Prabir; Mogilishetty, Gautham; Wall, Garth E; Brailey, Paul; Girnita, Alin; Woodle, E Steve (2009. ) Bortezomib-based treatment of antibody mediated rejection in pancreas allograft recipients. Clinical transplants, , 443-53

Everly, M J; Everly, J J; Susskind, B; Brailey, P; Arend, L J; Alloway, R R; Roy-Chaudhury, P; Govil, A; Mogilishetty, G; Rike, A H; Cardi, M; Wadih, G; Brown, E; Tevar, A; Woodle, E S Proteasome inhibition reduces donor-specific antibody levels.Transplantation proceedings, , 41 (1 ) ,105-7

Everly, Matthew J; Everly, Jason J; Susskind, Brian; Brailey, Paul; Arend, Lois J; Alloway, Rita R; Roy-Chaudhury, Prabir; Govil, Amit; Mogilishetty, Gautham; Rike, Adele H; Cardi, Michael; Wadih, George; Tevar, Amit; Woodle, E Steve (2008. ) Bortezomib provides effective therapy for antibody- and cell-mediated acute rejection.Transplantation, , 86 (12 ) ,1754-61

Woodle, E Steve; Alloway, Rita; Rike, Adele; Roy-Chaudhury, Prabir; Tevar, Amit; Susskind, Brian; Everly, Jason; Mogilishetty, Gautham; Brailey, Paul; Govil, Amit; Rudich, Steve; First, M Roy; Alexander, J Wesley; Munda, Rino; Cardi, Michael; Arend, Lois (2007. ) Corticosteroid elimination: the Cincinnati experience. Clinical transplants, , 51-60

Duncan, Heather J; Pittman, Susan; Govil, Amit; Sorn, Lisa; Bissler, Gloria; Schultz, Tersea; Faith, J; Kant, Shashi; Roy-Chaudhury, Prabir (2007. ) Alternative medicine use in dialysis patients: potential for good and bad!.Nephron. Clinical practice, , 105 (3 ) ,c108-13

Invited Publications

Woodle ES, Alloway RR, Govil A, et al (2007. ) Corticosteroid elimination: The Cincinnati experience .Clinical Transplants, 95 -104

Govil A, Walsh RC, Woodle ES, et al (2009. ) Bortezomib-based therapy for antibody medicated rejection in pancreas allograft recipients .Clinical Transplants, 443 -453

Presentations

Invited Presentations

Govil A (2000. ) Polyomavirus in renal transplant recipients: case reports and review of the literature .Division of Nephrology Fellows Grand Rounds, University of Cincinnati.

Govil A (2000. ) Acute Renal Failure in Bone Marrow Transplant Patients .Division of Nephrology Fellows Research Conference , University of Cincinnati.

Govil A (2000. ) Acute Renal Failure in the Intensive Care Unit .Residents' Forum, VAMC, Dayton, OH.

Govil A (2001. ) Sirolimus substitution for calcineurin-inhibitors in renal allograft recipients with calineurin-inhibitor nephrotoxicity .American Society of Transplantation, Chicago, IL.

Govil A (2001. ) Sirolimus substitution for calcineurin-inhibitors in renal allograft recipients with calineurin-inhibitor nephrotoxicity .Division of Nephrology Fellows Grand Rounds, University of Cincinnati.

Govil A (2010. ) Transplantation vs. Dialysis .Division of Nephrology Fellows Grand Rounds, University of Cincinnati.

Govil A (2011. ) Desensitization Protocols: What works and on whom? .National Kidney Foundation Spring Clinical Meetings, Las Vegas, NV.

Govil A (2012. ) Transplantation vs. Dialysis .National Kidney Foundation Regional Meeting, Columbus, OH.

Govil A, Peddi VR, First MR, et al (2001. ) Sirolimus substitutions for calcineurin-inhibitors in renal allograft recipients with calcineurin-inhibitor nephrotoxicity .American Society of Transplantation, Chicago, IL.

Govil A, Golconda M, Norman DJ, et al (2006. ) Calcineurin inhibitor withdrawal in HLA-identical sibling kidney transplant recipients: A 10-year single center experience .World Transplant Congress, Boston, MA.

Everly M, Everly J, Govil A, Woodle ES, et al (2008. ) Presence of donor specific humoral response in acute rejection significantly reduces long-term renal allograft survual .American Transplant Congress, Toronto, Ontario, Canada.

Everly M, Everly J, Govil A, Woodle ES, et al (2008. ) Early reduction in immunodominant de novo donor specific anti-HLA antibody levels predicts long term renal allograft survival .American Transplant Congress, Toronto, Ontario, Canada.

Mogilishetty G, Hair D, Govil A, Woodle ES, et al (2008. ) Comparison of immunosuppression related toxicities and complications in ocular surface transplant and renal transplant recipients: implications for composite tissue transplantation .American Transplant Congress, Toronto, Ontario, Canada.

Lee RA, Adele R, Govil A, Woodle ES, et al (2008. ) Thymoglobulin dosing intensity and density: effects on induction efficacy .American Transplant Congress, Toronto, Ontario, Canada.

Everly MJ, Govil A, Woodle ES, Roy-Chaughury P, et al (2009. ) Presence of donor specific humoral response in acute rejection significantly reduces long-term renal allograft survual .American Transplant Congress, Boston, MA.

Govil A, Everly M, Roy-Chaudhury P (2009. ) Glomerular C4d deposition and denovo donor specific antibodies are associated with poor prognosis in transplant glomerulopathy .American Transplant Congress, Boston, MA.

Everly MJ, Walsh RC, Govil A, Woodle ES, et al (2009. ) Bortezomib therapy for acute humoral rejection .European Society for Organ Transplantation, Paris, France.

Govil A, Arend L, Woodle ES, et al (2010. ) DSA and C4d deposition: Paradoxical dissociation in acute pancreas allograft rejection .American Transplant Congress, San Diego, CA.

Govil A, Walsh RC, Woodle ES, et al (2010. ) Bortezomib therapy for acute humoral rejection .American Transplant Congress, San Diego, CA.

Rike Shields A, Govil A, Woodle ES, et al (2010. ) Long term renal allograft survival following early corticosterois withdrawal: Measurement and risk factor assessment .American Transplant Congress, San Diego, CA.

Rike Shields A, Govil A, Woodle ES, et al (2010. ) Long term outcomes with early corticosterois withdrawal regimens in kidney transplantation: comparison to long term corticosteroid maintenance therapy .International Congress of the Transplantation Society, Vancouver, British Columbia, Canada.

Rike Shields A, Govil A, Woodle ES, et al (2010. ) Multivariate analyses of risk factors for death-censored graft loss in renal transplant recipients receiving early corticosteroid withdrawal .International Congress of the Transplantation Society, Vancouver, British Columbia, Canada.

Govil A, Walsh RC, Woodle ES, et al (2010. ) Antibody mediated rejection in pancreas allograft recipients: experience with bortezomib-based therapy .International Congress of the Transplantation Society, Vancouver, British Columbia, Canada.

Govil A, Tevar (2010. ) Dichotomoy between DSA and C4d deposition in pancreas allograft rejection .International Congress of the Transplantation Society, Vancouver, British Columbia, Canada.

Poster Presentations

Pitman S, Govil A, Roy-Chaudhury P, et al (2001. ) Alternative medicine use in dialysis patients: potential for good and bad! .ASN/ISN World Congress of Nephrology,

Govil A, Peddi VR, First MR, et al (2001. ) Sirlimus substitution for calcineurin-inhibitors in renal allograft recipients with nephrotoxicity .ASN/ISN World Congress of Nephrology,

Peddi VR, Govil A, First MR, et al (2002. ) Long-term follow up of Sirolimus substitution for calcineurin-inhibitors in renal allograft recipients with nephrotoxicity .ASN Congress of Nephrology,

Roy-Chaudhury P, Govil A, Cavallo T, et al (2002. ) C4d deposition in chronic allograft dysfunction .ASN Congress of Nephrology,

Govil A, Norman DJ, DeMattos AM, et al (2006. ) Risk factors associated with cardiac events post kidney transplantation: Importance of modifiable risk factors .World Transplant Congress, Boston, MA. .

Sadaka B, Govil A, Woodle ES, et al (2012. ) Rejection frequency and characterization in early corticosteroid minimization versus early corticosteroid withdrawal regimens in simultaneous kidney pancreas transplantation .American Transplant Congress, Boston, MA. .

Sadaka B, Govil A, Woodle ES, et al (2012. ) Early corticosteroid minimization versus early corticosteroid withdrawal in simultaneous kidney pancreas transplantation .American Transplant Congress, Boston, MA. .

Jepkorir C, Govil A, Woodle ES, et al (2012. ) Comparison of cardiovascular risk and cardiovascular events with early corticosteroid minimization versus early corticosteroid withdrawal in simultaneous kidney pancreas transplantation .American Transplant Congress, Boston, MA. .

Post Graduate Training and Education

01-1994-06-1995 Residency in Medicine, G. B. Pant Hospital, , New Delhi, India

07-1995-06-1996 Residency , ENT, Maulana Azad Medical College, , New Delhi, India

07-1996-06-1999 Residency , Internal Medicine, Downstate Medical Center, Kings County Medical Center and V.A. Medical Center, , State University of Health Sciences Center (SUNY), Brooklyn, NY

07-1999-06-2001 Fellow, Nephrology and Hypertension, University of Cincinnati, , Cincinnati, OH

07-2005-06-2006 Fellow, Transplant Medicine, Division of Renal Transplantation and Immunogenetics, , Oregon Health & Sciences University, Portland, OR

Keywords

BK virus nephropathy, AMR, DSA, Sirolimus, HLA identical kidney transplant, Kidney-pancreas transplant

Contact Information

Academic - Medical Sciences Building
Room 6213A
Cincinnati  45267
Phone: 513-558-5471
Fax: 513-558-4309
amit.govil@uc.edu