Michael Helmrath

Michael Helmrath , MD

Professor of Clinical-Affiliate

Director of Surgical Research and Director of Intestinal Rehabilitation Center, CCHMC

Cincinnati Children's Hospital Medical Center
Department of Pediatric Surgery
3333 Burnet Avenue
Cincinnati, Ohio 45229
Phone 513-636-8318
Email michael.helmrath@cchmc.org

Education

Bachelor's Degree: Miami University - Oxford 1987

Medical Degree: University of Cincinnati 1993

Master's Degree: University of Cincinnati 1989 (Physiology and Biophysics)

Research Fellow in Pediatric Surgery: Cincinnati Children's Hospital Medical Center 1997

ECMO Fellowship: Cincinnati Children's Hospital Medical Center 1997

General Surgery Residency: University of Cincinnati 2000

Fellowship in Pediatric Surgery: Baylor College of Medicine, Texas Children's Hospital of Houston 2002

Research and Practice Interests

Short Bowel Syndrome, Intestinal Stem Cell Research

Publications

Peer Reviewed Publications

Bout-Tabaku, Sharon; Michalsky, Marc P; Jenkins, Todd M; Baughcum, Amy; Zeller, Meg H; Brandt, Mary L; Courcoulas, Anita; Buncher, Ralph; Helmrath, Michael; Harmon, Carroll M; Chen, Mike K; Inge, Thomas H (2015. ) Musculoskeletal Pain, Self-reported Physical Function, and Quality of Life in the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Cohort.JAMA pediatrics, , 169 (6 ) ,552-9 More Information

Xanthakos, Stavra A; Jenkins, Todd M; Kleiner, David E; Boyce, Tawny W; Mourya, Reena; Karns, Rebekah; Brandt, Mary L; Harmon, Carroll M; Helmrath, Michael A; Michalsky, Marc P; Courcoulas, Anita P; Zeller, Meg H; Inge, Thomas H (2015. ) High Prevalence of Nonalcoholic Fatty Liver Disease in Adolescents Undergoing Bariatric Surgery.Gastroenterology, , More Information

Michalsky, Marc P; Inge, Thomas H; Simmons, Mark; Jenkins, Todd M; Buncher, Ralph; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Courcoulas, Anita; Chen, Michael; Horlick, Mary; Daniels, Stephen R; Urbina, Elaine M (2015. ) Cardiovascular Risk Factors in Severely Obese Adolescents: The Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Study.JAMA pediatrics, , 169 (5 ) ,438-44 More Information

Zeller, Meg H; Inge, Thomas H; Modi, Avani C; Jenkins, Todd M; Michalsky, Marc P; Helmrath, Michael; Courcoulas, Anita; Harmon, Carroll M; Rofey, Dana; Baughcum, Amy; Austin, Heather; Price, Karin; Xanthakos, Stavra A; Brandt, Mary L; Horlick, Mary; Buncher, Ralph (2015. ) Severe obesity and comorbid condition impact on the weight-related quality of life of the adolescent patient.The Journal of pediatrics, , 166 (3 ) ,651-9.e4 More Information

Inge, Thomas H; Boyce, Tawny W; Lee, Margaret; Kollar, Linda; Jenkins, Todd M; Brandt, Mary L; Helmrath, Michael; Xanthakos, Stavra A; Zeller, Meg H; Harmon, Carroll M; Courcoulas, Anita; Michalsky, Marc P (2014. ) Access to care for adolescents seeking weight loss surgery.Obesity (Silver Spring, Md.), , 22 (12 ) ,2593-7 More Information

Xiao, Nianzhou; Jenkins, Todd M; Nehus, Edward; Inge, Thomas H; Michalsky, Marc P; Harmon, Carroll M; Helmrath, Michael A; Brandt, Mary L; Courcoulas, Anita; Moxey-Mims, Marva; Mitsnefes, Mark M (2014. ) Kidney function in severely obese adolescents undergoing bariatric surgery.Obesity (Silver Spring, Md.), , 22 (11 ) ,2319-25 More Information

Michalsky, Marc P; Inge, Thomas H; Teich, Steven; Eneli, Ihuoma; Miller, Rosemary; Brandt, Mary L; Helmrath, Michael; Harmon, Carroll M; Zeller, Meg H; Jenkins, Todd M; Courcoulas, Anita; Buncher, Ralph C (2014. ) Adolescent bariatric surgery program characteristics: the Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study experience.Seminars in pediatric surgery, , 23 (1 ) ,5-10 More Information

Inge, Thomas H; Zeller, Meg H; Jenkins, Todd M; Helmrath, Michael; Brandt, Mary L; Michalsky, Marc P; Harmon, Carroll M; Courcoulas, Anita; Horlick, Mary; Xanthakos, Stavra A; Dolan, Larry; Mitsnefes, Mark; Barnett, Sean J; Buncher, Ralph (2014. ) Perioperative outcomes of adolescents undergoing bariatric surgery: the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study.JAMA pediatrics, , 168 (1 ) ,47-53 More Information

Ubesie, Agozie C; Kocoshis, Samuel A; Mezoff, Adam G; Henderson, Carol J; Helmrath, Michael A; Cole, Conrad R (2013. ) Multiple micronutrient deficiencies among patients with intestinal failure during and after transition to enteral nutrition.The Journal of pediatrics, , 163 (6 ) ,1692-6 More Information

Eradi, Balgopal; Hamrick, Miller; Bischoff, Andrea; Frischer, Jason S; Helmrath, Michael; Hall, Jennifer; Peña, Alberto; Levitt, Marc A (2013. ) The role of a colon resection in combination with a Malone appendicostomy as part of a bowel management program for the treatment of fecal incontinence.Journal of pediatric surgery, , 48 (11 ) ,2296-300 More Information

Hamrick, Miller; Helmrath, Michael; Bischoff, Andrea; Eradi, Balgopal; Levitt, Marc; Peña, Alberto (2011. ) Letter to the Editor regarding comparison of anorectal angle and continence after Georgeson and Peña procedures for high/intermediate imperforate anus.Journal of pediatric surgery, , 46 (5 ) ,1019-20; author repl More Information

Dehmer, Jeffrey J; Fuller, Megan K; Helmrath, Michael A (2011. ) Management of pediatric intestinal failure.Advances in pediatrics, , 58 (1 ) ,181-94 More Information

Inge, Thomas; Helmrath, Michael; Vierra, Mark (2010. ) The Santoro III massive enterectomy: how can we justify the risks in obese adolescents?.Obesity surgery, , 20 (12 ) ,1718-9 More Information

Brandt, Mary L; Harmon, Carroll M; Helmrath, Michael A; Inge, Thomas H; McKay, Siripoom V; Michalsky, Marc P (2010. ) Morbid obesity in pediatric diabetes mellitus: surgical options and outcomes.Nature reviews. Endocrinology, , 6 (11 ) ,637-45 More Information

Garrison, Aaron P; Helmrath, Michael A; Dekaney, Christopher M (2009. ) Intestinal stem cells.Journal of pediatric gastroenterology and nutrition, , 49 (1 ) ,2-7 More Information

Inge, Thomas H; Miyano, Go; Bean, Judy; Helmrath, Michael; Courcoulas, Anita; Harmon, Carroll M; Chen, Mike K; Wilson, Kimberly; Daniels, Stephen R; Garcia, Victor F; Brandt, Mary L; Dolan, Lawrence M (2009. ) Reversal of type 2 diabetes mellitus and improvements in cardiovascular risk factors after surgical weight loss in adolescents.Pediatrics, , 123 (1 ) ,214-22 More Information

Inge, Thomas; Helmrath, Michael; Vierra, Mark; Ikramuddin, Sayeed (2008. ) Challenges of adolescent bariatric surgery: tips for managing the extremely obese teen.Journal of laparoendoscopic & advanced surgical techniques. Part A, , 18 (1 ) ,157-69 More Information

Inge, Thomas H; Zeller, Meg; Harmon, Carroll; Helmrath, Michael; Bean, Judy; Modi, Avani; Horlick, Mary; Kalra, Maninder; Xanthakos, Stavra; Miller, Rosemary; Akers, Rachel; Courcoulas, Anita (2007. ) Teen-Longitudinal Assessment of Bariatric Surgery: methodological features of the first prospective multicenter study of adolescent bariatric surgery.Journal of pediatric surgery, , 42 (11 ) ,1969-71 More Information

Fuller, Megan K; Helmrath, Michael A (2007. ) Thoracic empyema, application of video-assisted thoracic surgery and its current management.Current opinion in pediatrics, , 19 (3 ) ,328-32 More Information

De Silva, Nirupama K; Helmrath, Michael A; Klish, William J (2007. ) Obesity in the adolescent female.Journal of pediatric and adolescent gynecology, , 20 (3 ) ,207-13 More Information

Helmrath, Michael A; Brandt, Mary L; Inge, Thomas H (2006. ) Adolescent obesity and bariatric surgery.The Surgical clinics of North America, , 86 (2 ) ,441-54, x More Information

Kenton, Alexander B; Hegemier, Suzanne; Smith, E O'Brian; O'Donovan, Donough J; Brandt, Mary L; Cass, Darrell L; Helmrath, Michael A; Washburn, Kimberly; Weihe, Elizabeth K; Fernandes, Caraciolo J (2005. ) Platelet transfusions in infants with necrotizing enterocolitis do not lower mortality but may increase morbidity.Journal of perinatology : official journal of the California Perinatal Association, , 25 (3 ) ,173-7 More Information

Kenton, Alexander B; O'Donovan, Donough; Cass, Darrell L; Helmrath, Michael A; Smith, E O'brian; Fernandes, Caraciolo J; Washburn, Kimberly; Weihe, Elizabeth K; Brandt, Mary L (2005. ) Severe thrombocytopenia predicts outcome in neonates with necrotizing enterocolitis.Journal of perinatology : official journal of the California Perinatal Association, , 25 (1 ) ,14-20 More Information

Klish, William J; Brandt, Mary L; Helmrath, Michael A (2004. ) Obesity surgery in pediatrics. Journal of pediatric gastroenterology and nutrition, , 39 (1 ) ,2-4

Inge, Thomas H; Krebs, Nancy F; Garcia, Victor F; Skelton, Joseph A; Guice, Karen S; Strauss, Richard S; Albanese, Craig T; Brandt, Mary L; Hammer, Lawrence D; Harmon, Carol M; Kane, Timothy D; Klish, William J; Oldham, Keith T; Rudolph, Colin D; Helmrath, Michael A; Donovan, Edward; Daniels, Stephen R (2004. ) Bariatric surgery for severely overweight adolescents: concerns and recommendations. Pediatrics, , 114 (1 ) ,217-23

Bertaux-Skeirik, Nina; Wunderlich, Mark; Teal, Emma; Chakrabarti, Jayati; Biesiada, Jacek; Mahe, Maxime; Sundaram, Nambirajan; Gabre, Joel; Hawkins, Jennifer; Gao, Jian; Engevik, Amy C; Yang, Li; Wang, Jiang; Goldenring, James R; Qualls, Joseph E; Medvedovic, Mario; Helmrath, Michael A; Diwan, Tayyab; Mulloy, James C; Zavros, Yana (2017. ) CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium.The Journal of pathology, , More Information

Zeller, Meg H; Pendery, Emma C; Reiter-Purtill, Jennifer; Hunsaker, Sanita L; Jenkins, Todd M; Helmrath, Michael A; Inge, Thomas H (2017. ) From adolescence to young adulthood: trajectories of psychosocial health following Roux-en-Y gastric bypass.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, , More Information

Asai, Akihiro; Aihara, Eitaro; Watson, Carey; Mourya, Reena; Mizuochi, Tatsuki; Shivakumar, Pranavkumar; Phelan, Kieran; Mayhew, Christopher; Helmrath, Michael; Takebe, Takanori; Wells, James; Bezerra, Jorge A (2017. ) Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells.Development (Cambridge, England), , 144 (6 ) ,1056-1064 More Information

Nalapareddy, Kodandaramireddy; Nattamai, Kalpana J; Kumar, Rupali S; Karns, Rebekah; Wikenheiser-Brokamp, Kathryn A; Sampson, Leesa L; Mahe, Maxime M; Sundaram, Nambirajan; Yacyshyn, Mary-Beth; Yacyshyn, Bruce; Helmrath, Michael A; Zheng, Yi; Geiger, Hartmut (2017. ) Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells.Cell reports, , 18 (11 ) ,2608-2621 More Information

Inge, Thomas H; Jenkins, Todd M; Xanthakos, Stavra A; Dixon, John B; Daniels, Stephen R; Zeller, Meg H; Helmrath, Michael A (2017. ) Long-term outcomes of bariatric surgery in adolescents with severe obesity (FABS-5+): a prospective follow-up analysis.The lancet. Diabetes & endocrinology, , 5 (3 ) ,165-173 More Information

Maxime, Mahe M; Brown, Nicole E; Poling, Holly M; Michael, Helmrath A (2017. ) In Vivo Model of Small Intestine.Methods in molecular biology (Clifton, N.J.), , 1597 ,229-245 More Information

Workman, Michael J; Mahe, Maxime M; Trisno, Stephen; Poling, Holly M; Watson, Carey L; Sundaram, Nambirajan; Chang, Ching-Fang; Schiesser, Jacqueline; Aubert, Philippe; Stanley, Edouard G; Elefanty, Andrew G; Miyaoka, Yuichiro; Mandegar, Mohammad A; Conklin, Bruce R; Neunlist, Michel; Brugmann, Samantha A; Helmrath, Michael A; Wells, James M (2017. ) Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system.Nature medicine, , 23 (1 ) ,49-59 More Information

Hirschl, Ronald B; Minneci, Peter; Gadepalli, Samir; Saito, Jacqueline M; Askegard-Giesmann, Johanna; Deans, Katherine; Downard, Cynthia; Fallat, Mary; Finnell, Maria; Helmrath, Michael; Kabre, Rashmi; Lal, David; Leys, Charles; Mak, Grace; Ostlie, Daniel; Rescorla, Fred; Sato, Thomas; St Peter, Shawn; von Allmen, Daniel; Warner, Brad (2016. ) Development of a multi-institutional clinical research consortium for pediatric surgery.Journal of pediatric surgery, , More Information

Lal, Dave R; Gadepalli, Samir K; Downard, Cynthia D; Ostlie, Daniel J; Minneci, Peter C; Swedler, Ruth M; Chelius, Thomas; Cassidy, Laura; Rapp, Cooper T; Deans, Katherine J; Fallat, Mary E; Finnell, S Maria E; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi S; Leys, Charles M; Mak, Grace; Raque, Jessica; Rescorla, Frederick J; Saito, Jacqueline M; St Peter, Shawn D; von Allmen, Daniel; Warner, Brad W; Sato, Thomas T (2016. ) Perioperative management and outcomes of esophageal atresia and tracheoesophageal fistula.Journal of pediatric surgery, , More Information

Cushing, Christopher C; Martinez-Leo, Bruno; Bischoff, Andrea; Hall, Jennifer; Helmrath, Michael; Dickie, Belinda H; Levitt, Marc A; Peña, Alberto; Zeller, Meg H; Frischer, Jason S (2016. ) Health-Related Quality of Life and Parental Stress in Children With Fecal Incontinence: A Normative Comparison.Journal of pediatric gastroenterology and nutrition, , 63 (6 ) ,633-636 More Information

Cohran, Valeria; Managlia, Elizabeth; Bradford, Emily M; Goretsky, Tatiana; Li, Ting; Katzman, Rebecca B; Cheresh, Paul; Brown, Jeffrey B; Hawkins, Jennifer; Liu, Shirley X L; De Plaen, Isabelle G; Weitkamp, Jörn-Hendrik; Helmrath, Michael; Zhang, Zheng; Barrett, Terrence A (2016. ) Epithelial PIK3R1 (p85) and TP53 Regulate Survivin Expression during Adaptation to Ileocecal Resection.The American journal of pathology, , 186 (7 ) ,1837-46 More Information

Engevik, Amy C; Feng, Rui; Choi, Eunyoung; White, Shana; Bertaux-Skeirik, Nina; Li, Jing; Mahe, Maxime M; Aihara, Eitaro; Yang, Li; DiPasquale, Betsy; Oh, Sunghee; Engevik, Kristen A; Giraud, Andrew S; Montrose, Marshall H; Medvedovic, Mario; Helmrath, Michael A; Goldenring, James R; Zavros, Yana (2016. ) The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach.Cellular and molecular gastroenterology and hepatology, , 2 (5 ) ,605-624 More Information

Mezoff, Ethan A; Hawkins, Jennifer A; Ollberding, Nicholas J; Karns, Rebekah; Morrow, Ardythe L; Helmrath, Michael A (2016. ) The human milk oligosaccharide 2'-fucosyllactose augments the adaptive response to extensive intestinal.American journal of physiology. Gastrointestinal and liver physiology, , 310 (6 ) ,G427-38 More Information

Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Helmrath, Michael A; Brandt, Mary L; Harmon, Carroll M; Zeller, Meg H; Chen, Mike K; Xanthakos, Stavra A; Horlick, Mary; Buncher, C Ralph (2016. ) Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents.The New England journal of medicine, , 374 (2 ) ,113-23 More Information

Moon, Changsuk; Zhang, Weiqiang; Sundaram, Nambirajan; Yarlagadda, Sunitha; Reddy, Vadde Sudhakar; Arora, Kavisha; Helmrath, Michael A; Naren, Anjaparavanda P (2015. ) Drug-induced secretory diarrhea: A role for CFTR.Pharmacological research, , 102 ,107-12 More Information

Aihara, Eitaro; Mahe, Maxime M; Schumacher, Michael A; Matthis, Andrea L; Feng, Rui; Ren, Wenwen; Noah, Taeko K; Matsu-ura, Toru; Moore, Sean R; Hong, Christian I; Zavros, Yana; Herness, Scott; Shroyer, Noah F; Iwatsuki, Ken; Jiang, Peihua; Helmrath, Michael A; Montrose, Marshall H (2015. ) Characterization of stem/progenitor cell cycle using murine circumvallate papilla taste bud organoid.Scientific reports, , 5 ,17185 More Information

Bouffi, Carine; Wikenheiser-Brokamp, Kathryn A; Chaturvedi, Praneet; Sundaram, Nambirajan; Goddard, Gillian R; Wunderlich, Mark; Brown, Nicole E; Staab, Janet F; Latanich, Rachel; Zachos, Nicholas C; Holloway, Emily M; Mahe, Maxime M; Poling, Holly M; Vales, Simon; Fisher, Garrett W; Spence, Jason R; Mulloy, James C; Zorn, Aaron M; Wells, James M; Helmrath, Michael A (2023. ) In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice.Nature biotechnology, , 41 (6 ) ,824-831 More Information

Singh, Akaljot; Poling, Holly M; Chaturvedi, Praneet; Thorner, Konrad; Sundaram, Nambirajan; Kechele, Daniel O; Childs, Charlie J; McCauley, Heather A; Fisher, Garrett W; Brown, Nicole E; Spence, Jason R; Wells, James M; Helmrath, Michael A (2023. ) Transplanted human intestinal organoids: a resource for modeling human intestinal development.Development (Cambridge, England), , 150 (9 ) , More Information

Zeller, Meg H; Strong, Heather; Reiter-Purtill, Jennifer; Jenkins, Todd M; Mitchell, James E; Michalsky, Marc P; Helmrath, Michael A (2023. ) Marijuana, e-cigarette, and tobacco product use in young adults who underwent pediatric bariatric surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, , 19 (5 ) ,512-521 More Information

Moran-Lev, Hadar; Kocoshis, Samuel A; Oliveira, Stephanie B; Helmrath, Michael; Cole, Conrad R (2023. ) Chronic Mucosal Inflammation in Pediatric Intestinal Failure Patients- a Unique Phenomenon.Journal of pediatric gastroenterology and nutrition, , More Information

O'Connell, Amy E; Raveenthiraraj, Sathuwarman; Adegboye, Comfort; Qi, Wanshu; Khetani, Radhika S; Singh, Akaljot; Sundaram, Nambirajam; Emeonye, Chidera; Lin, Jasmine; Goldsmith, Jeffrey D; Thiagarajah, Jay R; Carlone, Diana L; Turner, Jerrold R; Agrawal, Pankaj B; Helmrath, Michael; Breault, David T (2023. ) WNT2B Deficiency Causes Increased Susceptibility to Colitis in Mice and Impairs Intestinal Epithelial Development in Humans.bioRxiv : the preprint server for biology, , More Information

Gil, Lindsay A; Lutz, Carley M; Dillon, Patrick A; Downard, Cynthia D; Ehrlich, Peter F; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Hertweck, S Paige; Hirschl, Ronald B; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace Z; Markel, Troy A; Raiji, Manish T; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Stafford, Linda M Cherney; Deans, Katherine J; Minneci, Peter C; Hewitt, Geri D; Aldrink, Jennifer H (2023. ) Use and Accuracy of Intraoperative Frozen Section Analysis for Ovarian Masses in Children and Adolescents.Journal of pediatric and adolescent gynecology, , 36 (2 ) ,155-159 More Information

Marquart, John P; Bowder, Alexis N; Bence, Christina M; St Peter, Shawn D; Gadepalli, Samir K; Sato, Thomas T; Szabo, Aniko; Minneci, Peter C; Hirschl, Ronald B; Rymeski, Beth A; Downard, Cynthia D; Markel, Troy A; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Kabre, Rashmi D; Kohler, Jonathan E; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace Z; Port, Elissa; Saito, Jacqueline; Silverberg, Jared; Slidell, Mark B; Wright, Tiffany N; Lal, Dave R (2023. ) Thoracoscopy versus thoracotomy for esophageal atresia and tracheoesophageal fistula: Outcomes from the Midwest Pediatric Surgery Consortium.Journal of pediatric surgery, , 58 (1 ) ,27-33 More Information

Rosselot, Andrew E; Park, Miri; Kim, Mari; Matsu-Ura, Toru; Wu, Gang; Flores, Danilo E; Subramanian, Krithika R; Lee, Suengwon; Sundaram, Nambirajan; Broda, Taylor R; McCauley, Heather A; Hawkins, Jennifer A; Chetal, Kashish; Salomonis, Nathan; Shroyer, Noah F; Helmrath, Michael A; Wells, James M; Hogenesch, John B; Moore, Sean R; Hong, Christian I (2022. ) Ontogeny and function of the circadian clock in intestinal organoids.The EMBO journal, , 41 (2 ) ,e106973 More Information

Fraser, James A; Deans, Katherine J; Fallat, Mary E; Helmrath, Michael; Kabre, Rashmi; Leys, Charles M; Markel, Troy A; Dillon, Patrick A; Downard, Cynthia; Wright, Tiffany N; Gadepalli, Samir K; Grabowski, Julia E; Hirschl, Ronald; Johnson, Kevin N; Kohler, Jonathan E; Landman, Matthew P; Mak, Grace Z; Minneci, Peter C; Rymeski, Beth; Sato, Thomas T; Slater, Bethany J; Peter, Shawn D St; Fraser, Jason D (2022. ) Evaluating the risk of peri-umbilical hernia after sutured or sutureless gastroschisis closure.Journal of pediatric surgery, , 57 (12 ) ,786-791 More Information

Kunisaki, Shaun M; Saito, Jacqueline M; Fallat, Mary E; Peter, Shawn D St; Lal, Dave R; Karmakar, Monita; Deans, Katherine J; Gadepalli, Samir K; Hirschl, Ronald B; Minneci, Peter C; Helmrath, Michael A (2022. ) Fetal Risk Stratification and Outcomes in Children with Prenatally Diagnosed Lung Malformations: Results from a Multi-Institutional Research Collaborative.Annals of surgery, , 276 (5 ) ,e622-e630 More Information

Decker, Kristina M; Reiter-Purtill, Jennifer; Bejarano, Carolina M; Goldschmidt, Andrea B; Mitchell, James E; Jenkins, Todd M; Helmrath, Michael; Inge, Thomas H; Michalsky, Marc P; Zeller, Meg H (2022. ) Psychosocial predictors of problematic eating in young adults who underwent adolescent bariatric surgery.Obesity science & practice, , 8 (5 ) ,545-555 More Information

Pitstick, Amy L; Poling, Holly M; Sundaram, Nambirajan; Lewis, Phillip L; Kechele, Daniel O; Sanchez, J Guillermo; Scott, Melissa A; Broda, Taylor R; Helmrath, Michael A; Wells, James M; Mayhew, Christopher N (2022. ) Aggregation of cryopreserved mid-hindgut endoderm for more reliable and reproducible hPSC-derived small intestinal organoid generation.Stem cell reports, , 17 (8 ) ,1889-1902 More Information

Ding, Lin; Chakrabarti, Jayati; Sheriff, Sulaiman; Li, Qian; Thi Hong, Hahn Nguyen; Sontz, Ricky A; Mendoza, Zoe E; Schreibeis, Amanda; Helmrath, Michael A; Zavros, Yana; Merchant, Juanita L (2022. ) Toll-like Receptor 9 Pathway Mediates Schlafen+-MDSC Polarization During Helicobacter-induced Gastric Metaplasias.Gastroenterology, , 163 (2 ) ,411-425.e4 More Information

Engwall-Gill, Abigail J; Chan, Sherwin S; Boyd, Kevin P; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Bolger-Theut, Stephanie; Crotty, Eric J; Green, Jared R; Hulett Bowling, Rebecca L; Kumbhar, Sachin S; Rattan, Mantosh S; Young, Cody M; Canner, Joseph K; Deans, Katherine J; Gadepalli, Samir K; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Minneci, Peter C; Wright, Tiffany N; Kunisaki, Shaun M (2022. ) Accuracy of Chest Computed Tomography in Distinguishing Cystic Pleuropulmonary Blastoma From Benign Congenital Lung Malformations in Children.JAMA network open, , 5 (6 ) ,e2219814 More Information

Bowder, Alexis N; Bence, Christina M; Rymeski, Beth A; Gadepalli, Samir K; Sato, Thomas T; Szabo, Aniko; Arendonk, Kyle Van; Minneci, Peter C; Downard, Cynthia D; Hirschl, Ronald B; Markel, Troy; Courtney, Cathleen M; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Kabre, Rashmi D; Kohler, Jonathan E; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace; Port, Elissa; Saito, Jacqueline; Silverberg, Jared; Slidell, Mark B; St Peter, Shawn D; Troutt, Misty; Wright, Tiffany N; Lal, Dave R (2022. ) Acid suppression duration does not alter anastomotic stricture rates after esophageal atresia with distal tracheoesophageal fistula repair: A prospective multi-institutional cohort study.Journal of pediatric surgery, , 57 (6 ) ,975-980 More Information

Minneci, Peter C; Hade, Erinn M; Gil, Lindsay A; Metzger, Gregory A; Saito, Jacqueline M; Mak, Grace Z; Hirschl, Ronald B; Gadepalli, Samir; Helmrath, Michael A; Leys, Charles M; Sato, Thomas T; Lal, Dave R; Landman, Matthew P; Kabre, Rashmi; Fallat, Mary E; Cooper, Jennifer N; Deans, Katherine J (2022. ) Demographic and Clinical Characteristics Associated With the Failure of Nonoperative Management of Uncomplicated Appendicitis in Children: Secondary Analysis of a Nonrandomized Clinical Trial.JAMA network open, , 5 (5 ) ,e229712 More Information

Dekonenko, Charlene; Fraser, Jason D; Deans, Katherine; Fallat, Mary E; Helmrath, Michael; Kabre, Rashmi; Leys, Charles M; Burns, R Cartland; Corkum, Kristine; Dillon, Patrick A; Downard, Cynthia; Wright, Tiffany N; Gadepalli, Samir K; Grabowski, Julia; Hernandez, Edward; Hirschl, Ronald; Johnson, Kevin N; Kohler, Jonathan; Landman, Matthew P; Landisch, Rachel M; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter; Rymeski, Beth; Sato, Thomas T; Slater, Bethany J; Peter, St Shawn D (2022. ) Does Use of a Feeding Protocol Change Outcomes in Gastroschisis? A Report from the Midwest Pediatric Surgery Consortium.European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, , 32 (2 ) ,153-159 More Information

Capeling, Meghan M; Huang, Sha; Childs, Charlie J; Wu, Joshua H; Tsai, Yu-Hwai; Wu, Angeline; Garg, Neil; Holloway, Emily M; Sundaram, Nambirajan; Bouffi, Carine; Helmrath, Michael; Spence, Jason R (2022. ) Suspension culture promotes serosal mesothelial development in human intestinal organoids.Cell reports, , 38 (7 ) ,110379 More Information

McNelis, Kera; Poindexter, Anne; Goddard, Gillian; Riddle, Stefanie; Wessel, Jacqueline; Helmrath, Michael (2022. ) Body Composition of Infants With Congenital Gastroschisis.Journal of pediatric gastroenterology and nutrition, , 74 (2 ) ,e35-e38 More Information

Chakrabarti, Jayati; Dua-Awereh, Martha; Schumacher, Michael; Engevik, Amy; Hawkins, Jennifer; Helmrath, Michael A; Zavros, Yana (2022. ) Sonic Hedgehog acts as a macrophage chemoattractant during regeneration of the gastric epithelium.NPJ Regenerative medicine, , 7 (1 ) ,3 More Information

Eicher, Alexandra K; Kechele, Daniel O; Sundaram, Nambirajan; Berns, H Matthew; Poling, Holly M; Haines, Lauren E; Sanchez, J Guillermo; Kishimoto, Keishi; Krishnamurthy, Mansa; Han, Lu; Zorn, Aaron M; Helmrath, Michael A; Wells, James M (2022. ) Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells.Cell stem cell, , 29 (1 ) ,36-51.e6 More Information

Chakrabarti, Jayati; Koh, Vivien; Steele, Nina; Hawkins, Jennifer; Ito, Yoshiaki; Merchant, Juanita L; Wang, Jiang; Helmrath, Michael A; Ahmad, Syed A; So, Jimmy Bok Yan; Yong, Wei Peng; Zavros, Yana (2021. ) Disruption of Her2-Induced PD-L1 Inhibits Tumor Cell Immune Evasion in Patient-Derived Gastric Cancer Organoids.Cancers, , 13 (24 ) , More Information

Weller, Jennine H; Peter, Shawn D St; Fallat, Mary E; Saito, Jacqueline M; Burns, Cartland R; Deans, Katherine J; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Minneci, Peter C; Wright, Tiffany N; Kunisaki, Shaun M (2021. ) Thoracoscopic versus open lobectomy in infants with congenital lung malformations: A multi-institutional propensity score analysis.Journal of pediatric surgery, , 56 (12 ) ,2148-2156 More Information

Criss, Zachary K; Bhasin, Nobel; Di Rienzi, Sara C; Rajan, Anubama; Deans-Fielder, Kali; Swaminathan, Ganesh; Kamyabi, Nabiollah; Zeng, Xi-Lei; Doddapaneni, Harsha; Menon, Vipin K; Chakravarti, Deepavali; Estrella, Clarissa; Yu, Xiaomin; Patil, Ketki; Petrosino, Joseph F; Fleet, James C; Verzi, Michael P; Christakos, Sylvia; Helmrath, Michael A; Arimura, Sumimasa; DePinho, Ronald A; Britton, Robert A; Maresso, Anthony W; Grande-Allen, K Jane; Blutt, Sarah E; Crawford, Sue E; Estes, Mary K; Ramani, Sasirekha; Shroyer, Noah F (2021. ) Drivers of transcriptional variance in human intestinal epithelial organoids.Physiological genomics, , 53 (11 ) ,486-508 More Information

Goddard, Gillian R; McNelis, Kera; Poindexter, Anne; Jenkins, Todd; Wessel, Jacqueline; Nathan, Amy T; Helmrath, Michael A; Poindexter, Brenda (2021. ) Quality Improvement Efforts Reduce Incidence of Surgical Necrotizing Enterocolitis and Related Deaths.American journal of perinatology, , 38 (13 ) ,1386-1392 More Information

Koh, Vivien; Chakrabarti, Jayati; Torvund, Meaghan; Steele, Nina; Hawkins, Jennifer A; Ito, Yoshiaki; Wang, Jiang; Helmrath, Michael A; Merchant, Juanita L; Ahmed, Syed A; Shabbir, Asim; Yan So, Jimmy Bok; Yong, Wei Peng; Zavros, Yana (2021. ) Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids.Cancer letters, , 518 ,59-71 More Information

Shah, Amy S; Helmrath, Michael A; Inge, Thomas H; Xanthakos, Stavra A; Kelsey, Megan M; Jenkins, Todd; Trout, Andrew T; Browne, Lorna; Nadeau, Kristen J (2021. ) Study protocol: a prospective controlled clinical trial to assess surgical or medical treatment for paediatric type 2 diabetes (ST2OMP).BMJ open, , 11 (8 ) ,e047766 More Information

Lim, Irene Isabel P; Cushing, Christopher C; Jenkins, Todd; Troutt, Misty; Zeller, Margaret H; Hossain, Monir; Rymeski, Beth; Helmrath, Michael; Frischer, Jason S (2021. ) Prospective quality of life outcomes in pediatric fecal incontinence following bowel management.Journal of pediatric surgery, , 56 (8 ) ,1459-1464 More Information

Dekonenko, Charlene; Fraser, Jason D; Deans, Katherine J; Fallat, Mary E; Helmrath, Michael; Kabre, Rashmi; Leys, Charles M; Burns, R Cartland; Corkumd, Kristine; Dillon, Patrick A; Downard, Cynthia; Wright, Tiffany N; Gadepalli, Samir K; Grabowski, Julia E; Hernandez, Edward; Hirschl, Ronald; Johnson, Kevin N; Kohler, Jonathan E; Landman, Matthew P; Landisch, Rachel M; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter C; Rymeski, Beth; Sato, Thomas T; Slater, Bethany J; St Peter, Shawn D (2021. ) Outcomes in gastroschisis: expectations in the postnatal period for simple vs complex gastroschisis.Journal of perinatology : official journal of the California Perinatal Association, , 41 (7 ) ,1755-1759 More Information

Kasendra, Magdalena; Troutt, Misty; Broda, Taylor; Bacon, W Clark; Wang, Timothy C; Niland, Joyce C; Helmrath, Michael A (2021. ) Intestinal organoids: roadmap to the clinic.American journal of physiology. Gastrointestinal and liver physiology, , 321 (1 ) ,G1-G10 More Information

Moreno-Fernandez, Maria E; Giles, Daniel A; Oates, Jarren R; Chan, Calvin C; Damen, Michelle S M A; Doll, Jessica R; Stankiewicz, Traci E; Chen, Xiaoting; Chetal, Kashish; Karns, Rebekah; Weirauch, Matthew T; Romick-Rosendale, Lindsey; Xanthakos, Stavra A; Sheridan, Rachel; Szabo, Sara; Shah, Amy S; Helmrath, Michael A; Inge, Thomas H; Deshmukh, Hitesh; Salomonis, Nathan; Divanovic, Senad (2021. ) PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease.Cell metabolism, , 33 (6 ) ,1187-1204.e9 More Information

Arora, Kavisha; Yang, Fanmuyi; Brewington, John; McPhail, Gary; Cortez, Alexander R; Sundaram, Nambirajan; Ramananda, Yashaswini; Ogden, Herbert; Helmrath, Michael; Clancy, John P; Naren, Anjaparavanda P (2021. ) Patient personalized translational tools in cystic fibrosis to transform data from bench to bed-side and back.American journal of physiology. Gastrointestinal and liver physiology, , 320 (6 ) ,G1123-G1130 More Information

Chan, Calvin C; Harley, Isaac T W; Pfluger, Paul T; Trompette, Aurelien; Stankiewicz, Traci E; Allen, Jessica L; Moreno-Fernandez, Maria E; Damen, Michelle S M A; Oates, Jarren R; Alarcon, Pablo C; Doll, Jessica R; Flick, Matthew J; Flick, Leah M; Sanchez-Gurmaches, Joan; Mukherjee, Rajib; Karns, Rebekah; Helmrath, Michael; Inge, Thomas H; Weisberg, Stuart P; Pamp, Sünje J; Relman, David A; Seeley, Randy J; Tschöp, Matthias H; Karp, Christopher L; Divanovic, Senad (2021. ) A BAFF/APRIL axis regulates obesogenic diet-driven weight gain.Nature communications, , 12 (1 ) ,2911 More Information

Kunisaki, Shaun M; Lal, Dave R; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Fox, Zachary D; Heider, Amer; Chan, Sherwin S; Boyd, Kevin P; Burns, R Cartland; Deans, Katherine J; Gadepalli, Samir K; Hirschl, Ronald B; Kabre, Rashmi; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Minneci, Peter C; Wright, Tiffany N; Helmrath, Michael A (2021. ) Pleuropulmonary Blastoma in Pediatric Lung Lesions.Pediatrics, , 147 (4 ) , More Information

McNelis, Kera; Goddard, Gillian; Jenkins, Todd; Poindexter, Anne; Wessel, Jacqueline; Helmrath, Michael; Poindexter, Brenda (2021. ) Delay in achieving enteral autonomy and growth outcomes in very low birth weight infants with surgical necrotizing enterocolitis.Journal of perinatology : official journal of the California Perinatal Association, , 41 (1 ) ,150-156 More Information

Bence, Christina M; Rymeski, Beth; Gadepalli, Samir; Sato, Thomas T; Minneci, Peter C; Downard, Cynthia; Hirschl, Ronald B; Amin, Ruchi A; Burns, R Cartland; Cherney-Stafford, Linda; Courtney, Cathleen M; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia E; Helmrath, Michael A; Kabre, Rashmi D; Kohler, Jonathan E; Landman, Matthew P; Lawrence, Amy E; Leys, Charles M; Mak, Grace Z; Port, Elissa; Saito, Jacqueline M; Silverberg, Jared; Slidell, Mark B; St Peter, Shawn D; Troutt, Misty; Walker, Sarah; Wright, Tiffany; Lal, Dave R (2021. ) Clinical outcomes following implementation of a management bundle for esophageal atresia with distal tracheoesophageal fistula.Journal of pediatric surgery, , 56 (1 ) ,47-54 More Information

Fraser, Jason D; Deans, Katherine J; Fallat, Mary E; Helmrath, Michael A; Kabre, Rashmi; Leys, Charles M; Burns, R Cartland; Corkum, Kristine; Dillon, Patrick A; Downard, Cynthia D; Gadepalli, Samir K; Grabowski, Julia E; Hernandez, Edward; Hirschl, Ronald B; Johnson, Kevin N; Kohler, Jonathan E; Landman, Matthew P; Landisch, Rachel M; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter C; Rymeski, Beth; Sato, Thomas T; Scannell, Madeline; Slater, Bethany J; Wilkinson, Kathryn H; Wright, Tiffany N; St Peter, Shawn D (2020. ) Sutureless vs sutured abdominal wall closure for gastroschisis: Operative characteristics and early outcomes from the Midwest Pediatric Surgery Consortium.Journal of pediatric surgery, , 55 (11 ) ,2284-2288 More Information

Valvi, Damaskini; Walker, Douglas I; Inge, Thomas; Bartell, Scott M; Jenkins, Todd; Helmrath, Michael; Ziegler, Thomas R; La Merrill, Michele A; Eckel, Sandrah P; Conti, David; Liang, Yongliang; Jones, Dean P; McConnell, Rob; Chatzi, Leda (2020. ) Environmental chemical burden in metabolic tissues and systemic biological pathways in adolescent bariatric surgery patients: A pilot untargeted metabolomic approach.Environment international, , 143 ,105957 More Information

McCauley, Heather A; Matthis, Andrea L; Enriquez, Jacob R; Nichol, Jonah T; Sanchez, J Guillermo; Stone, William J; Sundaram, Nambirajan; Helmrath, Michael A; Montrose, Marshall H; Aihara, Eitaro; Wells, James M (2020. ) Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport.Nature communications, , 11 (1 ) ,4791 More Information

Singh, Akaljot; Poling, Holly M; Spence, Jason R; Wells, James M; Helmrath, Michael A (2020. ) Gastrointestinal organoids: a next-generation tool for modeling human development.American journal of physiology. Gastrointestinal and liver physiology, , 319 (3 ) ,G375-G381 More Information

Singh, Akaljot; Poling, Holly M; Sundaram, Nambirajan; Brown, Nicole; Wells, James M; Helmrath, Michael A (2020. ) Evaluation of transplantation sites for human intestinal organoids.PloS one, , 15 (8 ) ,e0237885 More Information

Minneci, Peter C; Hade, Erinn M; Lawrence, Amy E; Sebastião, Yuri V; Saito, Jacqueline M; Mak, Grace Z; Fox, Christa; Hirschl, Ronald B; Gadepalli, Samir; Helmrath, Michael A; Kohler, Jonathan E; Leys, Charles M; Sato, Thomas T; Lal, Dave R; Landman, Matthew P; Kabre, Rashmi; Fallat, Mary E; Cooper, Jennifer N; Deans, Katherine J (2020. ) Association of Nonoperative Management Using Antibiotic Therapy vs Laparoscopic Appendectomy With Treatment Success and Disability Days in Children With Uncomplicated Appendicitis.JAMA, , 324 (6 ) ,581-593 More Information

Kunisaki, Shaun M; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Lal, Dave R; Johnson, Kevin N; Mon, Rodrigo A; Adams, Cheryl; Aladegbami, Bola; Bence, Christina; Burns, R Cartland; Corkum, Kristine S; Deans, Katherine J; Downard, Cynthia D; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Kabre, Rashmi; Landman, Matthew P; Leys, Charles M; Linden, Allison F; Lopez, Joseph J; Mak, Grace Z; Minneci, Peter C; Rademacher, Brooks L; Shaaban, Aimen; Walker, Sarah K; Wright, Tiffany N; Hirschl, Ronald B (2020. ) Development of a multi-institutional registry for children with operative congenital lung malformations.Journal of pediatric surgery, , 55 (7 ) ,1313-1318 More Information

Chan, Calvin C; Damen, Michelle S M A; Moreno-Fernandez, Maria E; Stankiewicz, Traci E; Cappelletti, Monica; Alarcon, Pablo C; Oates, Jarren R; Doll, Jessica R; Mukherjee, Rajib; Chen, Xiaoting; Karns, Rebekah; Weirauch, Matthew T; Helmrath, Michael A; Inge, Thomas H; Divanovic, Senad (2020. ) Type I interferon sensing unlocks dormant adipocyte inflammatory potential.Nature communications, , 11 (1 ) ,2745 More Information

Dewberry, Lindel C; Jalivand, Anahita; Gupta, Resmi; Jenkins, Todd M; Beamish, Andrew; Inge, Thomas H; Courcoulas, Anita; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Chen, Mike; Dixon, John B; Zeller, Margaret; Michalsky, Marc P (2020. ) Weight Loss and Health Status 5 Years After Adjustable Gastric Banding in Adolescents.Obesity surgery, , 30 (6 ) ,2388-2394 More Information

Xanthakos, Stavra A; Khoury, Jane C; Inge, Thomas H; Jenkins, Todd M; Modi, Avani C; Michalsky, Marc P; Chen, Mike K; Courcoulas, Anita P; Harmon, Carroll M; Brandt, Mary L; Helmrath, Michael A; Kalkwarf, Heidi J (2020. ) Nutritional Risks in Adolescents After Bariatric Surgery.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, , 18 (5 ) ,1070-1081.e5 More Information

Shah, Amy S; Nadeau, Kristen J; Helmrath, Michael A; Inge, Thomas H; Xanthakos, Stavra A; Kelsey, Megan M (2020. ) Metabolic outcomes of surgery in youth with type 2 diabetes.Seminars in pediatric surgery, , 29 (1 ) ,150893 More Information

Lamoshi, Abdulrouf; Chernoguz, Artur; Harmon, Carroll M; Helmrath, Michael (2020. ) Complications of bariatric surgery in adolescents.Seminars in pediatric surgery, , 29 (1 ) ,150888 More Information

Sitzman, Thomas J; Carle, Adam C; Lundberg, Jaclyn N; Heaton, Pamela C; Helmrath, Michael A; Trotman, Carroll-Ann; Britto, Maria T (2020. ) Marked Variation Exists Among Surgeons and Hospitals in the Use of Secondary Cleft Lip Surgery.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, , 57 (2 ) ,198-207 More Information

Vales, Simon; Poling, Holly M; Sundaram, Nambirajan; Helmrath, Michael A; Mahe, Maxime M (2020. ) In Vivo Human PSC-Derived Intestinal Organoids to Study Stem Cell Maintenance.Methods in molecular biology (Clifton, N.J.), , 2171 ,201-214 More Information

Pradhan, Suman; Karve, Sayali S; Weiss, Alison A; Hawkins, Jennifer; Poling, Holly M; Helmrath, Michael A; Wells, James M; McCauley, Heather A (2020. ) Tissue Responses to Shiga Toxin in Human Intestinal Organoids.Cellular and molecular gastroenterology and hepatology, , 10 (1 ) ,171-190 More Information

Leys, Charles M; Hirschl, Ronald B; Kohler, Jonathan E; Cherney-Stafford, Linda; Marka, Nicholas; Fallat, Mary E; Gadepalli, Samir K; Fraser, Jason D; Grabowski, Julia; Burns, R Cartland; Downard, Cynthia D; Foley, David S; Halleran, Devin R; Helmrath, Michael A; Kabre, Rashmi; Knezevich, Michelle S; Lal, Dave R; Landman, Matthew P; Lawrence, Amy E; Mak, Grace Z; Minneci, Peter C; Musili, Ninette; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Warner, Brad W; Ostlie, Daniel J (2020. ) Changing the Paradigm for Management of Pediatric Primary Spontaneous Pneumothorax: A Simple Aspiration Test Predicts Need for Operation.Journal of pediatric surgery, , 55 (1 ) ,169-175 More Information

Bout-Tabaku, Sharon; Gupta, Resmi; Jenkins, Todd M; Ryder, Justin R; Baughcum, Amy E; Jackson, Rebecca D; Inge, Thomas H; Dixon, John B; Helmrath, Michael A; Courcoulas, Anita P; Mitchell, James E; Harmon, Carroll M; Xie, Changchun; Michalsky, Marc P (2019. ) Musculoskeletal Pain, Physical Function, and Quality of Life After Bariatric Surgery.Pediatrics, , 144 (6 ) , More Information

Goddard, Gillian R; Kotagal, Meera; Jenkins, Todd M; Kollar, Linda M; Inge, Thomas H; Helmrath, Michael A (2019. ) Weight loss after sleeve gastrectomy in developmentally delayed adolescents and young adults.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, , 15 (10 ) ,1662-1667 More Information

Noah, Taeko K; Knoop, Kathryn A; McDonald, Keely G; Gustafsson, Jenny K; Waggoner, Lisa; Vanoni, Simone; Batie, Matthew; Arora, Kavisha; Naren, Anjaparavanda P; Wang, Yui-Hsi; Lukacs, Nicholas W; Munitz, Ariel; Helmrath, Michael A; Mahe, Maxime M; Newberry, Rodney D; Hogan, Simon P (2019. ) IL-13-induced intestinal secretory epithelial cell antigen passages are required for IgE-mediated food-induced anaphylaxis.The Journal of allergy and clinical immunology, , 144 (4 ) ,1058-1073.e3 More Information

Inge, Thomas H; Courcoulas, Anita P; Helmrath, Michael A (2019. ) Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults. Reply.The New England journal of medicine, , 381 (9 ) ,e17 More Information

Minneci, Peter C; Hade, Erinn M; Lawrence, Amy E; Saito, Jacqueline M; Mak, Grace Z; Hirschl, Ronald B; Gadepalli, Samir; Helmrath, Michael A; Leys, Charles M; Sato, Thomas T; Lal, Dave R; Landman, Matthew P; Kabre, Rashmi; Fallat, Mary E; Fischer, Beth A; Cooper, Jennifer N; Deans, Katherine J (2019. ) Multi-institutional trial of non-operative management and surgery for uncomplicated appendicitis in children: Design and rationale.Contemporary clinical trials, , 83 ,10-17 More Information

Capurro, Mariana I; Greenfield, Laura K; Prashar, Akriti; Xia, Sunny; Abdullah, Majd; Wong, Harikesh; Zhong, Xi Zoe; Bertaux-Skeirik, Nina; Chakrabarti, Jayati; Siddiqui, Iram; O'Brien, Catherine; Dong, Xianping; Robinson, Lisa; Peek, Richard M; Philpott, Dana J; Zavros, Yana; Helmrath, Michael; Jones, Nicola L (2019. ) VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1.Nature microbiology, , 4 (8 ) ,1411-1423 More Information

Kunisaki, Shaun M; Saito, Jacqueline M; Fallat, Mary E; St Peter, Shawn D; Kim, Aimee G; Johnson, Kevin N; Mon, Rodrigo A; Adams, Cheryl; Aladegbami, Bola; Bence, Christina; Burns, R Cartland; Corkum, Kristine S; Deans, Katherine J; Downard, Cynthia D; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Kabre, Rashmi; Lal, Dave R; Landman, Matthew P; Leys, Charles M; Linden, Allison F; Lopez, Joseph J; Mak, Grace Z; Minneci, Peter C; Rademacher, Brooks L; Shaaban, Aimen; Walker, Sarah K; Wright, Tiffany N; Hirschl, Ronald B (2019. ) Current operative management of congenital lobar emphysema in children: A report from the Midwest Pediatric Surgery Consortium.Journal of pediatric surgery, , 54 (6 ) ,1138-1142 More Information

Minneci, Peter C; Kabre, Rashmi S; Mak, Grace Z; Halleran, Devin R; Cooper, Jennifer N; Afrazi, Amin; Calkins, Casey M; Corkum, Kristine; Downard, Cynthia D; Ehrlich, Peter; Fraser, Jason D; Gadepalli, Samir K; Helmrath, Michael A; Kohler, Jonathan E; Landisch, Rachel; Landman, Matthew P; Lee, Constance; Leys, Charles M; Lodwick, Daniel L; McLeod, Jennifer; Mon, Rodrigo; McClure, Beth; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Wood, Richard; Levitt, Marc A; Deans, Katherine J (2019. ) Can fecal continence be predicted in patients born with anorectal malformations?.Journal of pediatric surgery, , 54 (6 ) ,1159-1163 More Information

Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Brandt, Mary L; Xanthakos, Stavra A; Dixon, John B; Harmon, Carroll M; Chen, Mike K; Xie, Changchun; Evans, Mary E; Helmrath, Michael A (2019. ) Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults.The New England journal of medicine, , 380 (22 ) ,2136-2145 More Information

Múnera, Jorge O; Sundaram, Nambirajan; Rankin, Scott A; Hill, David; Watson, Carey; Mahe, Maxime; Vallance, Jefferson E; Shroyer, Noah F; Sinagoga, Katie L; Zarzoso-Lacoste, Adrian; Hudson, Jonathan R; Howell, Jonathan C; Chatuvedi, Praneet; Spence, Jason R; Shannon, John M; Zorn, Aaron M; Helmrath, Michael A; Wells, James M (2019. ) Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling.Cell stem cell, , 24 (5 ) ,829 More Information

Sitzman, Thomas J; Carle, Adam C; Heaton, Pamela C; Helmrath, Michael A; Britto, Maria T (2019. ) Five-Fold Variation Among Surgeons and Hospitals in the Use of Secondary Palate Surgery.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, , 56 (5 ) ,586-594 More Information

Lal, Dave R; Gadepalli, Samir K; Downard, Cynthia D; Minneci, Peter C; Knezevich, Michelle; Chelius, Thomas H; Rapp, Cooper T; Billmire, Deborah; Bruch, Steven; Carland Burns, R; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia; Hebel, Ferdynand; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Kohler, Jonathan; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Ostlie, Daniel J; Raque, Jessica; Rymeski, Beth; Saito, Jacqueline M; St Peter, Shawn D; von Allmen, Daniel; Warner, Brad W; Sato, Thomas T (2019. ) Infants with esophageal atresia and right aortic arch: Characteristics and outcomes from the Midwest Pediatric Surgery Consortium.Journal of pediatric surgery, , 54 (4 ) ,688-692 More Information

Capeling, Meghan M; Czerwinski, Michael; Huang, Sha; Tsai, Yu-Hwai; Wu, Angeline; Nagy, Melinda S; Juliar, Benjamin; Sundaram, Nambirajan; Song, Yang; Han, Woojin M; Takayama, Shuichi; Alsberg, Eben; Garcia, Andres J; Helmrath, Michael; Putnam, Andrew J; Spence, Jason R (2019. ) Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids.Stem cell reports, , 12 (2 ) ,381-394 More Information

Holokai, Loryn; Chakrabarti, Jayati; Broda, Taylor; Chang, Julie; Hawkins, Jennifer A; Sundaram, Nambirajan; Wroblewski, Lydia E; Peek, Richard M; Wang, Jiang; Helmrath, Michael; Wells, James M; Zavros, Yana (2019. ) Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection.PLoS pathogens, , 15 (1 ) ,e1007468 More Information

Steele, Nina G; Chakrabarti, Jayati; Wang, Jiang; Biesiada, Jacek; Holokai, Loryn; Chang, Julie; Nowacki, Lauren M; Hawkins, Jennifer; Mahe, Maxime; Sundaram, Nambirajan; Shroyer, Noah; Medvedovic, Mario; Helmrath, Michael; Ahmad, Syed; Zavros, Yana (2019. ) An Organoid-Based Preclinical Model of Human Gastric Cancer.Cellular and molecular gastroenterology and hepatology, , 7 (1 ) ,161-184 More Information

Sinagoga, Katie L; McCauley, Heather A; Múnera, Jorge O; Reynolds, Nichole A; Enriquez, Jacob R; Watson, Carey; Yang, Hsiu-Chiung; Helmrath, Michael A; Wells, James M (2018. ) Deriving functional human enteroendocrine cells from pluripotent stem cells.Development (Cambridge, England), , 145 (19 ) , More Information

Cortez, Alexander R; Poling, Holly M; Brown, Nicole E; Singh, Akaljot; Mahe, Maxime M; Helmrath, Michael A (2018. ) Transplantation of human intestinal organoids into the mouse mesentery: A more physiologic and anatomic engraftment site.Surgery, , 164 (4 ) ,643-650 More Information

Kelly, Daniel; Kotliar, Michael; Woo, Vivienne; Jagannathan, Sajjeev; Whitt, Jordan; Moncivaiz, Jessica; Aronow, Bruce J; Dubinsky, Marla C; Hyams, Jeffrey S; Markowitz, James F; Baldassano, Robert N; Stephens, Michael C; Walters, Thomas D; Kugathasan, Subra; Haberman, Yael; Sundaram, Nambirajan; Rosen, Michael J; Helmrath, Michael; Karns, Rebekah; Barski, Artem; Denson, Lee A; Alenghat, Theresa (2018. ) Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease.JCI insight, , 3 (18 ) , More Information

Brode, Cassie; Ratcliff, Megan; Reiter-Purtill, Jennifer; Hunsaker, Sanita; Helmrath, Michael; Zeller, Meg (2018. ) Predictors of Preoperative Program Non-Completion in Adolescents Referred for Bariatric Surgery.Obesity surgery, , 28 (9 ) ,2853-2859 More Information

Lal, Dave R; Gadepalli, Samir K; Downard, Cynthia D; Ostlie, Daniel J; Minneci, Peter C; Swedler, Ruth M; Chelius, Thomas H; Cassidy, Laura; Rapp, Cooper T; Billmire, Deborah; Bruch, Steven; Burns, R Carland; Deans, Katherine J; Fallat, Mary E; Fraser, Jason D; Grabowski, Julia; Hebel, Ferdynand; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi; Kohler, Jonathan; Landman, Matthew P; Leys, Charles M; Mak, Grace Z; Raque, Jessica; Rymeski, Beth; Saito, Jacqueline M; St Peter, Shawn D; von Allmen, Daniel; Warner, Brad W; Sato, Thomas T (2018. ) Challenging surgical dogma in the management of proximal esophageal atresia with distal tracheoesophageal fistula: Outcomes from the Midwest Pediatric Surgery Consortium.Journal of pediatric surgery, , 53 (7 ) ,1267-1272 More Information

Poling, Holly M; Wu, David; Brown, Nicole; Baker, Michael; Hausfeld, Taylor A; Huynh, Nhan; Chaffron, Samuel; Dunn, James C Y; Hogan, Simon P; Wells, James M; Helmrath, Michael A; Mahe, Maxime M (2018. ) Mechanically induced development and maturation of human intestinal organoids in vivo.Nature biomedical engineering, , 2 (6 ) ,429-442 More Information

Takebe, Takanori; Wells, James M; Helmrath, Michael A; Zorn, Aaron M (2018. ) Organoid Center Strategies for Accelerating Clinical Translation.Cell stem cell, , 22 (6 ) ,806-809 More Information

Cushing, Christopher C; Threlkeld, Melody R S; Martinez-Leo, Bruno; Hall, Jennifer; Hossain, Monir; Dickie, Belinda H; Rymeski, Beth; Helmrath, Michael; Zeller, Meg H; Frischer, Jason S (2018. ) Initial development and validation of a fecal incontinence-specific quality of life measure.Journal of pediatric surgery, , 53 (6 ) ,1148-1153 More Information

Minneci, Peter C; Kabre, Rashmi S; Mak, Grace Z; Halleran, Devin R; Cooper, Jennifer N; Afrazi, Amin; Calkins, Casey M; Downard, Cynthia D; Ehrlich, Peter; Fraser, Jason; Gadepalli, Samir K; Helmrath, Michael A; Kohler, Jonathan E; Landisch, Rachel; Landman, Matthew P; Lee, Constance; Leys, Charles M; Lodwick, Daniel L; Mon, Rodrigo; McClure, Beth; Rymeski, Beth; Saito, Jacqueline M; Sato, Thomas T; St Peter, Shawn D; Wood, Richard; Levitt, Marc A; Deans, Katherine J (2018. ) Screening practices and associated anomalies in infants with anorectal malformations: Results from the Midwest Pediatric Surgery Consortium.Journal of pediatric surgery, , 53 (6 ) ,1163-1167 More Information

Marchix, Justine; Goddard, Gillian; Helmrath, Michael A (2018. ) Host-Gut Microbiota Crosstalk in Intestinal Adaptation.Cellular and molecular gastroenterology and hepatology, , 6 (2 ) ,149-162 More Information

Michalsky, Marc P; Inge, Thomas H; Jenkins, Todd M; Xie, Changchun; Courcoulas, Anita; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Chen, Mike; Dixon, John B; Urbina, Elaine M (2018. ) Cardiovascular Risk Factors After Adolescent Bariatric Surgery.Pediatrics, , 141 (2 ) , More Information

Sarwer, David B; Dilks, Rebecca J; Spitzer, Jacqueline C; Berkowitz, Robert I; Wadden, Thomas A; Moore, Renee H; Chittams, Jesse L; Brandt, Mary L; Chen, Mike K; Courcoulas, Anita P; Harmon, Carroll M; Helmrath, Michael A; Michalsky, Marc P; Xanthakos, Stavra A; Zeller, Meg H; Jenkins, Todd M; Inge, Thomas H (2017. ) Changes in Dietary Intake and Eating Behavior in Adolescents After Bariatric Surgery: an Ancillary Study to the Teen-LABS Consortium.Obesity surgery, , 27 (12 ) ,3082-3091 More Information

Wessel, Jacqueline; Kotagal, Meera; Helmrath, Michael A (2017. ) Management of Pediatric Intestinal Failure.Advances in pediatrics, , 64 (1 ) ,253-267 More Information

Múnera, Jorge O; Sundaram, Nambirajan; Rankin, Scott A; Hill, David; Watson, Carey; Mahe, Maxime; Vallance, Jefferson E; Shroyer, Noah F; Sinagoga, Katie L; Zarzoso-Lacoste, Adrian; Hudson, Jonathan R; Howell, Jonathan C; Chatuvedi, Praneet; Spence, Jason R; Shannon, John M; Zorn, Aaron M; Helmrath, Michael A; Wells, James M (2017. ) Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling.Cell stem cell, , 21 (1 ) ,51-64.e6 More Information

Mahe, Maxime M; Brown, Nicole E; Poling, Holly M; Helmrath, Michael A (2017. ) Erratum to: In Vivo Model of Small Intestine.Methods in molecular biology (Clifton, N.J.), , 1597 ,E1 More Information

Contact Information

Academic - Cincinnati Children's Hospital Medical Center
Department of Pediatric Surgery
Cincinnati  Ohio, 45229
Phone: 513-636-8318
michael.helmrath@cchmc.org