Michael Helmrath

Michael Helmrath , MD

Professor of Clinical-Affiliate

Director of Surgical Research and Director of Intestinal Rehabilitation Center, CCHMC

Cincinnati Children's Hospital Medical Center
Department of Pediatric Surgery
3333 Burnet Avenue
Cincinnati, Ohio 45229
Phone 513-636-8318
Email michael.helmrath@cchmc.org

Education

Bachelor's Degree: Miami University - Oxford 1987

Medical Degree: University of Cincinnati 1993

Master's Degree: University of Cincinnati 1989 (Physiology and Biophysics)

Research Fellow in Pediatric Surgery: Cincinnati Children's Hospital Medical Center 1997

ECMO Fellowship: Cincinnati Children's Hospital Medical Center 1997

General Surgery Residency: University of Cincinnati 2000

Fellowship in Pediatric Surgery: Baylor College of Medicine, Texas Children's Hospital of Houston 2002

Research and Practice Interests

Short Bowel Syndrome, Intestinal Stem Cell Research

Publications

Peer Reviewed Publications

Bout-Tabaku, Sharon; Michalsky, Marc P; Jenkins, Todd M; Baughcum, Amy; Zeller, Meg H; Brandt, Mary L; Courcoulas, Anita; Buncher, Ralph; Helmrath, Michael; Harmon, Carroll M; Chen, Mike K; Inge, Thomas H (2015. ) Musculoskeletal Pain, Self-reported Physical Function, and Quality of Life in the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Cohort.JAMA pediatrics, , 169 (6 ) ,552-9 More Information

Xanthakos, Stavra A; Jenkins, Todd M; Kleiner, David E; Boyce, Tawny W; Mourya, Reena; Karns, Rebekah; Brandt, Mary L; Harmon, Carroll M; Helmrath, Michael A; Michalsky, Marc P; Courcoulas, Anita P; Zeller, Meg H; Inge, Thomas H (2015. ) High Prevalence of Nonalcoholic Fatty Liver Disease in Adolescents Undergoing Bariatric Surgery.Gastroenterology, , More Information

Michalsky, Marc P; Inge, Thomas H; Simmons, Mark; Jenkins, Todd M; Buncher, Ralph; Helmrath, Michael; Brandt, Mary L; Harmon, Carroll M; Courcoulas, Anita; Chen, Michael; Horlick, Mary; Daniels, Stephen R; Urbina, Elaine M (2015. ) Cardiovascular Risk Factors in Severely Obese Adolescents: The Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Study.JAMA pediatrics, , 169 (5 ) ,438-44 More Information

Zeller, Meg H; Inge, Thomas H; Modi, Avani C; Jenkins, Todd M; Michalsky, Marc P; Helmrath, Michael; Courcoulas, Anita; Harmon, Carroll M; Rofey, Dana; Baughcum, Amy; Austin, Heather; Price, Karin; Xanthakos, Stavra A; Brandt, Mary L; Horlick, Mary; Buncher, Ralph (2015. ) Severe obesity and comorbid condition impact on the weight-related quality of life of the adolescent patient.The Journal of pediatrics, , 166 (3 ) ,651-9.e4 More Information

Inge, Thomas H; Boyce, Tawny W; Lee, Margaret; Kollar, Linda; Jenkins, Todd M; Brandt, Mary L; Helmrath, Michael; Xanthakos, Stavra A; Zeller, Meg H; Harmon, Carroll M; Courcoulas, Anita; Michalsky, Marc P (2014. ) Access to care for adolescents seeking weight loss surgery.Obesity (Silver Spring, Md.), , 22 (12 ) ,2593-7 More Information

Xiao, Nianzhou; Jenkins, Todd M; Nehus, Edward; Inge, Thomas H; Michalsky, Marc P; Harmon, Carroll M; Helmrath, Michael A; Brandt, Mary L; Courcoulas, Anita; Moxey-Mims, Marva; Mitsnefes, Mark M (2014. ) Kidney function in severely obese adolescents undergoing bariatric surgery.Obesity (Silver Spring, Md.), , 22 (11 ) ,2319-25 More Information

Michalsky, Marc P; Inge, Thomas H; Teich, Steven; Eneli, Ihuoma; Miller, Rosemary; Brandt, Mary L; Helmrath, Michael; Harmon, Carroll M; Zeller, Meg H; Jenkins, Todd M; Courcoulas, Anita; Buncher, Ralph C (2014. ) Adolescent bariatric surgery program characteristics: the Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study experience.Seminars in pediatric surgery, , 23 (1 ) ,5-10 More Information

Inge, Thomas H; Zeller, Meg H; Jenkins, Todd M; Helmrath, Michael; Brandt, Mary L; Michalsky, Marc P; Harmon, Carroll M; Courcoulas, Anita; Horlick, Mary; Xanthakos, Stavra A; Dolan, Larry; Mitsnefes, Mark; Barnett, Sean J; Buncher, Ralph (2014. ) Perioperative outcomes of adolescents undergoing bariatric surgery: the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study.JAMA pediatrics, , 168 (1 ) ,47-53 More Information

Ubesie, Agozie C; Kocoshis, Samuel A; Mezoff, Adam G; Henderson, Carol J; Helmrath, Michael A; Cole, Conrad R (2013. ) Multiple micronutrient deficiencies among patients with intestinal failure during and after transition to enteral nutrition.The Journal of pediatrics, , 163 (6 ) ,1692-6 More Information

Eradi, Balgopal; Hamrick, Miller; Bischoff, Andrea; Frischer, Jason S; Helmrath, Michael; Hall, Jennifer; Peña, Alberto; Levitt, Marc A (2013. ) The role of a colon resection in combination with a Malone appendicostomy as part of a bowel management program for the treatment of fecal incontinence.Journal of pediatric surgery, , 48 (11 ) ,2296-300 More Information

Hamrick, Miller; Helmrath, Michael; Bischoff, Andrea; Eradi, Balgopal; Levitt, Marc; Peña, Alberto (2011. ) Letter to the Editor regarding comparison of anorectal angle and continence after Georgeson and Peña procedures for high/intermediate imperforate anus.Journal of pediatric surgery, , 46 (5 ) ,1019-20; author repl More Information

Dehmer, Jeffrey J; Fuller, Megan K; Helmrath, Michael A (2011. ) Management of pediatric intestinal failure.Advances in pediatrics, , 58 (1 ) ,181-94 More Information

Inge, Thomas; Helmrath, Michael; Vierra, Mark (2010. ) The Santoro III massive enterectomy: how can we justify the risks in obese adolescents?.Obesity surgery, , 20 (12 ) ,1718-9 More Information

Brandt, Mary L; Harmon, Carroll M; Helmrath, Michael A; Inge, Thomas H; McKay, Siripoom V; Michalsky, Marc P (2010. ) Morbid obesity in pediatric diabetes mellitus: surgical options and outcomes.Nature reviews. Endocrinology, , 6 (11 ) ,637-45 More Information

Garrison, Aaron P; Helmrath, Michael A; Dekaney, Christopher M (2009. ) Intestinal stem cells.Journal of pediatric gastroenterology and nutrition, , 49 (1 ) ,2-7 More Information

Inge, Thomas H; Miyano, Go; Bean, Judy; Helmrath, Michael; Courcoulas, Anita; Harmon, Carroll M; Chen, Mike K; Wilson, Kimberly; Daniels, Stephen R; Garcia, Victor F; Brandt, Mary L; Dolan, Lawrence M (2009. ) Reversal of type 2 diabetes mellitus and improvements in cardiovascular risk factors after surgical weight loss in adolescents.Pediatrics, , 123 (1 ) ,214-22 More Information

Inge, Thomas; Helmrath, Michael; Vierra, Mark; Ikramuddin, Sayeed (2008. ) Challenges of adolescent bariatric surgery: tips for managing the extremely obese teen.Journal of laparoendoscopic & advanced surgical techniques. Part A, , 18 (1 ) ,157-69 More Information

Inge, Thomas H; Zeller, Meg; Harmon, Carroll; Helmrath, Michael; Bean, Judy; Modi, Avani; Horlick, Mary; Kalra, Maninder; Xanthakos, Stavra; Miller, Rosemary; Akers, Rachel; Courcoulas, Anita (2007. ) Teen-Longitudinal Assessment of Bariatric Surgery: methodological features of the first prospective multicenter study of adolescent bariatric surgery.Journal of pediatric surgery, , 42 (11 ) ,1969-71 More Information

Fuller, Megan K; Helmrath, Michael A (2007. ) Thoracic empyema, application of video-assisted thoracic surgery and its current management.Current opinion in pediatrics, , 19 (3 ) ,328-32 More Information

De Silva, Nirupama K; Helmrath, Michael A; Klish, William J (2007. ) Obesity in the adolescent female.Journal of pediatric and adolescent gynecology, , 20 (3 ) ,207-13 More Information

Helmrath, Michael A; Brandt, Mary L; Inge, Thomas H (2006. ) Adolescent obesity and bariatric surgery.The Surgical clinics of North America, , 86 (2 ) ,441-54, x More Information

Kenton, Alexander B; Hegemier, Suzanne; Smith, E O'Brian; O'Donovan, Donough J; Brandt, Mary L; Cass, Darrell L; Helmrath, Michael A; Washburn, Kimberly; Weihe, Elizabeth K; Fernandes, Caraciolo J (2005. ) Platelet transfusions in infants with necrotizing enterocolitis do not lower mortality but may increase morbidity.Journal of perinatology : official journal of the California Perinatal Association, , 25 (3 ) ,173-7 More Information

Kenton, Alexander B; O'Donovan, Donough; Cass, Darrell L; Helmrath, Michael A; Smith, E O'brian; Fernandes, Caraciolo J; Washburn, Kimberly; Weihe, Elizabeth K; Brandt, Mary L (2005. ) Severe thrombocytopenia predicts outcome in neonates with necrotizing enterocolitis.Journal of perinatology : official journal of the California Perinatal Association, , 25 (1 ) ,14-20 More Information

Klish, William J; Brandt, Mary L; Helmrath, Michael A (2004. ) Obesity surgery in pediatrics. Journal of pediatric gastroenterology and nutrition, , 39 (1 ) ,2-4

Inge, Thomas H; Krebs, Nancy F; Garcia, Victor F; Skelton, Joseph A; Guice, Karen S; Strauss, Richard S; Albanese, Craig T; Brandt, Mary L; Hammer, Lawrence D; Harmon, Carol M; Kane, Timothy D; Klish, William J; Oldham, Keith T; Rudolph, Colin D; Helmrath, Michael A; Donovan, Edward; Daniels, Stephen R (2004. ) Bariatric surgery for severely overweight adolescents: concerns and recommendations. Pediatrics, , 114 (1 ) ,217-23

Bertaux-Skeirik, Nina; Wunderlich, Mark; Teal, Emma; Chakrabarti, Jayati; Biesiada, Jacek; Mahe, Maxime; Sundaram, Nambirajan; Gabre, Joel; Hawkins, Jennifer; Gao, Jian; Engevik, Amy C; Yang, Li; Wang, Jiang; Goldenring, James R; Qualls, Joseph E; Medvedovic, Mario; Helmrath, Michael A; Diwan, Tayyab; Mulloy, James C; Zavros, Yana (2017. ) CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium.The Journal of pathology, , More Information

Zeller, Meg H; Pendery, Emma C; Reiter-Purtill, Jennifer; Hunsaker, Sanita L; Jenkins, Todd M; Helmrath, Michael A; Inge, Thomas H (2017. ) From adolescence to young adulthood: trajectories of psychosocial health following Roux-en-Y gastric bypass.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, , More Information

Asai, Akihiro; Aihara, Eitaro; Watson, Carey; Mourya, Reena; Mizuochi, Tatsuki; Shivakumar, Pranavkumar; Phelan, Kieran; Mayhew, Christopher; Helmrath, Michael; Takebe, Takanori; Wells, James; Bezerra, Jorge A (2017. ) Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells.Development (Cambridge, England), , 144 (6 ) ,1056-1064 More Information

Nalapareddy, Kodandaramireddy; Nattamai, Kalpana J; Kumar, Rupali S; Karns, Rebekah; Wikenheiser-Brokamp, Kathryn A; Sampson, Leesa L; Mahe, Maxime M; Sundaram, Nambirajan; Yacyshyn, Mary-Beth; Yacyshyn, Bruce; Helmrath, Michael A; Zheng, Yi; Geiger, Hartmut (2017. ) Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells.Cell reports, , 18 (11 ) ,2608-2621 More Information

Inge, Thomas H; Jenkins, Todd M; Xanthakos, Stavra A; Dixon, John B; Daniels, Stephen R; Zeller, Meg H; Helmrath, Michael A (2017. ) Long-term outcomes of bariatric surgery in adolescents with severe obesity (FABS-5+): a prospective follow-up analysis.The lancet. Diabetes & endocrinology, , 5 (3 ) ,165-173 More Information

Maxime, Mahe M; Brown, Nicole E; Poling, Holly M; Michael, Helmrath A (2017. ) In Vivo Model of Small Intestine.Methods in molecular biology (Clifton, N.J.), , 1597 ,229-245 More Information

Workman, Michael J; Mahe, Maxime M; Trisno, Stephen; Poling, Holly M; Watson, Carey L; Sundaram, Nambirajan; Chang, Ching-Fang; Schiesser, Jacqueline; Aubert, Philippe; Stanley, Edouard G; Elefanty, Andrew G; Miyaoka, Yuichiro; Mandegar, Mohammad A; Conklin, Bruce R; Neunlist, Michel; Brugmann, Samantha A; Helmrath, Michael A; Wells, James M (2017. ) Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system.Nature medicine, , 23 (1 ) ,49-59 More Information

Hirschl, Ronald B; Minneci, Peter; Gadepalli, Samir; Saito, Jacqueline M; Askegard-Giesmann, Johanna; Deans, Katherine; Downard, Cynthia; Fallat, Mary; Finnell, Maria; Helmrath, Michael; Kabre, Rashmi; Lal, David; Leys, Charles; Mak, Grace; Ostlie, Daniel; Rescorla, Fred; Sato, Thomas; St Peter, Shawn; von Allmen, Daniel; Warner, Brad (2016. ) Development of a multi-institutional clinical research consortium for pediatric surgery.Journal of pediatric surgery, , More Information

Lal, Dave R; Gadepalli, Samir K; Downard, Cynthia D; Ostlie, Daniel J; Minneci, Peter C; Swedler, Ruth M; Chelius, Thomas; Cassidy, Laura; Rapp, Cooper T; Deans, Katherine J; Fallat, Mary E; Finnell, S Maria E; Helmrath, Michael A; Hirschl, Ronald B; Kabre, Rashmi S; Leys, Charles M; Mak, Grace; Raque, Jessica; Rescorla, Frederick J; Saito, Jacqueline M; St Peter, Shawn D; von Allmen, Daniel; Warner, Brad W; Sato, Thomas T (2016. ) Perioperative management and outcomes of esophageal atresia and tracheoesophageal fistula.Journal of pediatric surgery, , More Information

Cushing, Christopher C; Martinez-Leo, Bruno; Bischoff, Andrea; Hall, Jennifer; Helmrath, Michael; Dickie, Belinda H; Levitt, Marc A; Peña, Alberto; Zeller, Meg H; Frischer, Jason S (2016. ) Health-Related Quality of Life and Parental Stress in Children With Fecal Incontinence: A Normative Comparison.Journal of pediatric gastroenterology and nutrition, , 63 (6 ) ,633-636 More Information

Cohran, Valeria; Managlia, Elizabeth; Bradford, Emily M; Goretsky, Tatiana; Li, Ting; Katzman, Rebecca B; Cheresh, Paul; Brown, Jeffrey B; Hawkins, Jennifer; Liu, Shirley X L; De Plaen, Isabelle G; Weitkamp, Jörn-Hendrik; Helmrath, Michael; Zhang, Zheng; Barrett, Terrence A (2016. ) Epithelial PIK3R1 (p85) and TP53 Regulate Survivin Expression during Adaptation to Ileocecal Resection.The American journal of pathology, , 186 (7 ) ,1837-46 More Information

Engevik, Amy C; Feng, Rui; Choi, Eunyoung; White, Shana; Bertaux-Skeirik, Nina; Li, Jing; Mahe, Maxime M; Aihara, Eitaro; Yang, Li; DiPasquale, Betsy; Oh, Sunghee; Engevik, Kristen A; Giraud, Andrew S; Montrose, Marshall H; Medvedovic, Mario; Helmrath, Michael A; Goldenring, James R; Zavros, Yana (2016. ) The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach.Cellular and molecular gastroenterology and hepatology, , 2 (5 ) ,605-624 More Information

Mezoff, Ethan A; Hawkins, Jennifer A; Ollberding, Nicholas J; Karns, Rebekah; Morrow, Ardythe L; Helmrath, Michael A (2016. ) The human milk oligosaccharide 2'-fucosyllactose augments the adaptive response to extensive intestinal.American journal of physiology. Gastrointestinal and liver physiology, , 310 (6 ) ,G427-38 More Information

Inge, Thomas H; Courcoulas, Anita P; Jenkins, Todd M; Michalsky, Marc P; Helmrath, Michael A; Brandt, Mary L; Harmon, Carroll M; Zeller, Meg H; Chen, Mike K; Xanthakos, Stavra A; Horlick, Mary; Buncher, C Ralph (2016. ) Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents.The New England journal of medicine, , 374 (2 ) ,113-23 More Information

Moon, Changsuk; Zhang, Weiqiang; Sundaram, Nambirajan; Yarlagadda, Sunitha; Reddy, Vadde Sudhakar; Arora, Kavisha; Helmrath, Michael A; Naren, Anjaparavanda P (2015. ) Drug-induced secretory diarrhea: A role for CFTR.Pharmacological research, , 102 ,107-12 More Information

Aihara, Eitaro; Mahe, Maxime M; Schumacher, Michael A; Matthis, Andrea L; Feng, Rui; Ren, Wenwen; Noah, Taeko K; Matsu-ura, Toru; Moore, Sean R; Hong, Christian I; Zavros, Yana; Herness, Scott; Shroyer, Noah F; Iwatsuki, Ken; Jiang, Peihua; Helmrath, Michael A; Montrose, Marshall H (2015. ) Characterization of stem/progenitor cell cycle using murine circumvallate papilla taste bud organoid.Scientific reports, , 5 ,17185 More Information

Contact Information

Academic - Cincinnati Children's Hospital Medical Center
Department of Pediatric Surgery
Cincinnati  Ohio, 45229
Phone: 513-636-8318
michael.helmrath@cchmc.org