James P. Herman , PHD

DR. JAMES HERMAN earned his B.S. in Chemistry/Psychology at Hobart College and his Ph.D. from the University of Rochester in 1987, from the Department of Neurobiology and Anatomy. Dr. Herman was a Postdoctoral Fellow at the Mental Health Research Institute at the University of Michigan. He began his career in the Department of Anatomy and Neurobiology at the University of Kentucky, where he was an Assoicate Professor and the James and Barbara Holsinger Chair of Anatomy and Neurobiology. Dr. Herman joined the University of Cincinnati faculty in 2000 and is currently the Director of the Laboratory of Stress Neurobiology, Professor of Psychiatry and Behavioral Neuroscience, and Director of the Center for Basic Neuroscience Research. Dr. Herman's major research interests include structural, functional and molecular biological principles underlying brain stress integration and pathology.

Research Description

The brain is at the center of a complex physiological process orchestrating secretion of stress hormones. Integration of the stress response occurs by way of a defined array of central stress-integrative neurons, which initiate a neuroendocrine cascade resulting in steroid secretion by the adrenal glands. Dr. Herman's laboratory is geared toward examining the relationship between the physiological actions of central nervous system stress circuits and their place in the central nervous system. Present studies focus on: 1) limbic system regulation of the stress response and, consequently, on the generation of stress-related disorders, ranging from major depressive illness to Post-Traumatic Stress Disorder to essential hypertension to neurodegeneration and aging, and 2) defining the role of central adrenocorticosteroid receptors in transducing stress-related signals in normal physiology, aging and disease states. Experimental approaches include genomic methods to discovery of novel genes and microRNAs involved in stress integration; use of gene knockdown and gain-of-function methods (conditional knockout/transgenic mice and viral vectors) to assess the role of specific molecular species in stress regulation and pathology;  and combinations of in situ hybridization, immunohistochemistry and tract-tracing for establishing the biochemical signatures of defined circuits within the brain-stress axis.

Bachelor's Degree: Hobart College (Chemistry/Psychology)

Doctoral Degree: University of Rochester 1987 (Neurobiology and Anatomy)

Post-Doctoral Fellowship: Mental Health Research Institute at the University of Michigan

Dr. Herman's major research interests include structural, functional and molecular biological principles underlying brain stress integration.

Research Description: The brain is at the center of a complex physiological process orchestrating secretion of stress hormones. Integration of the stress response occurs by way of a defined array of central stress-integrative neurons, which initiate a neuroendocrine cascade resulting in steroid secretion by the adrenal glands.

Dr. Herman's laboratory is geared toward examining the relationship between the physiological actions of central nervous system stress circuits and their place in the central nervous system.

Present studies focus on:
1) limbic system regulation of the stress response and, consequently, on the generation of stress-related disorders, ranging from major depressive illness to essential hypertension to neurodegeneration and aging, and

2) defining the role of central adrenocorticosteroid receptors in transducing stress-related signals in normal physiology, aging and disease states.

Experimental approaches include in situ hybridization, RNAse protection and PCR methods for localizing and quantifying gene expression and mRNA levels in identified neuronal populations; immunoautoradiography, Western blot and gel mobility shift assays for assessing regulation and functional integrity of stress-related proteins; and combinations of in situ hybridization, immunohistochemistry and tract-tracing for establishing the biochemical signatures of defined circuits within the brain-stress axis.

Future Projects
- Functional reorganization of neurotransmission in stress and disease
- Altered glucocorticoid signaling in brain aging and affective illness

10-01-1991 -06-30-1996 Associate Professor, Department of Anatomy and Neurobiology, University of Kentucky, Lexington, KY

01-01-2000 -06-03-2018 Professor , Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, Cincinnati, OH

07-01-1996 -12-31-1999 Associate Professor, Department of Anatomy and Neurobiology, University of Kentucky, Lexington, KY

07-01-2018 -To Present Professor and Chair, Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio

Grant: #CVB 2017 Investigators:Herman, James; Martelle, Susan 10-27-2017 -11-26-2018 Cohen Veterans Bioscience The role of stress hormones and dopamine in a novel genetic rat model of PTSD Role:PI $130,676.00 Active Level:Private Non-Profit

Grant: #T32NS007453 Investigators:Herman, James; Seroogy, Kim 07-01-2016 -06-30-2021 National Institute of Neurological Disorders and Stroke Predoctoral Training Program in the Neurosciences Role:PI $153,282.00 Active Level:Federal

Grant: #R01 MH017378 Investigators:McNamara, Robert; 03-09-2016 -01-31-2020 NIH/NIMH Risk and resilience factors for frontolimbic connectivity deficits Role:Collaborator $316,654 Active Type:Grant

Investigators:Herman, James 01-01-2016 -06-30-2016 College of Medicine Pilot Award Modulation of Prefrontal Cortical Gene Expression by Chronic Stress: A Single-cell Transcriptome Analysis Role:PI $25,000 Completed Type:Grant

Grant: #T32 NS00743 Investigators:Herman 2016 -2021 NINDS Predoctoral Training Program in the Neurosciences Role:PI $153,282 Active Type:Grant

Grant: #URC Interdisciplinary awards AY2014-15 Investigators:Herman, James; Song, Seongho; Ulrich-Lai, Yvonne; Wang, Xia 05-01-2015 -04-30-2016 UC Neuronal Network Discovery in ‘Comfort’ Food Model: A Bayesian Learning Approach Role:Collaborator $25,000.00 Completed

Grant: #2 R01MH049698-21A1 Investigators:Herman, James 08-15-2014 -06-30-2019 National Institute of Mental Health Functional Anatomy of Limbic-Neuroendocrine Circuits Role:PI $498,385.00 Active Type:Grant

Grant: #VA IPA Investigators:Herman, James 04-01-2014 -09-30-2014 Department of Veterans Affairs VA IPA for James Herman Role:PI $6,534.00 Active Level:Federal

Grant: #1R01MH101729 Investigators:Herman, James 02-10-2014 -01-31-2019 National Institute of Mental Health Adolescent Stress and Prefrontal Cortical Circuitry Role:PI $395,000 Active Type:Grant

Grant: #T32DK059803 Investigators:Woods, Stephen 07-01-2013 -06-30-2018 National Inst of Diabetes and Digestive and Kidney Disease Training Program in Neuroendocrinology of Homeostasis Role:Collaborator $217,444 Active Type:Grant

Grant: #F31MH097430 Investigators:Benoit, Stephen; Herman, James; McKlveen, Jessica 09-16-2012 -09-15-2014 National Institute of Mental Health Prefrontal GR Signaling and Memory Role:Collaborator $69,482.00 Completed Type:Grant

Grant: #K99HL111319 Investigators:Herman, James; Ryan, Karen; Seeley, Randy 06-01-2012 -02-28-2014 National Heart, Lung and Blood Institute CNS PPARg, Stress, and Cardiovascular Disease Role:Collaborator $238,398.00 Completed Type:Grant

Grant: #R01 MH093362 Investigators:Herman, James; Krause, Eric; Sah, Renu 02-10-2012 -11-30-2016 National Institute of Mental Health Acid-Sensing and Panic Role:Collaborator $764,987.00 Active Type:Grant

Grant: #11-272-RH-03CRD (CRADA) Investigators:Herman, James; Seroogy, Kim 09-29-2011 -09-29-2014 Air Force Research Laboratory Effects of Stress on Performance Role:PI $.00 Completed Type:Grant

Grant: #VA-IPA 9666 Investigators:Herman, James 06-01-2011 -05-31-2012 Department of Veterans Affairs Intergovernmental Personnel Act Agreement for James Herman Role:PI $29,921.00 Completed

Grant: #R21 MH090574 Investigators:Herman, James 06-01-2011 -05-31-2014 National Institute of Mental Health Stress Regulation of Non-Coding RNAs Role:PI $443,462.00 Completed Type:Grant

Grant: #R21 MH0905674 Investigators:Herman 2011 -2013 NIMH Stress Regulation of Non-Coding RNAs in Prefrontal Cortex Role:PI $248,159 Completed Type:Grant

Investigators:Seroogy, Fleming, Herman 2011 -2012 Gardner Family Center A Novel Parkinson’s Disease Knockout Rat Model: Effects of Stress on Nigrostriatal Dysfunction Role:co-PI Completed Type:Grant

Grant: #61-0095UC / P50-NS058830 Investigators:Herman, James; Seroogy, Kim 08-01-2010 -07-31-2014 National Institute of Neurological Disorders and Stroke Project 4: Glucocorticoid Mechanisms of Stress-Induced Depression and Parkinsonian Symptomology Role:Collaborator $185,708.00 Completed Type:Grant

Grant: #R01 MH069860 Investigators:Herman, James; Sakai, Randall; Seeley, Randy 07-19-2010 -03-31-2015 National Institute of Mental Health Brainstem Mechanisms of Stress Regulation Role:PI $1,482,603.00 Completed Type:Grant

Grant: #T32 NS007453 Investigators:Broderick, Joseph; Herman, James; Kao, Winston Whei Yang; Strakowski, Stephen 07-01-2010 -06-30-2015 National Institute of Neurological Disorders and Stroke Predoctoral Training Program in the Neurosciences Role:PI $629,724.00 Active Level:Federal

Grant: #F4FDBL0091M001 Investigators:Herman, James 04-01-2010 -03-31-2011 Air Force Research Laboratory Molecular Underpinnings of Cognitive Response to Chronic Variable Stress Using BXD Recombinant Inbred Mice Role:PI $100,000.00 Completed Type:Grant

Grant: #R01 MH069860 Investigators:Herman 2010 -2015 NIMH Brainstem Mechanisms of Stress Regulation Role:PI 1,412,000 Completed Type:Grant

Grant: #P50 NS058830 Investigators:Behbehani, Michael; Collier, Timothy; Herman, James; Lipton, Jack; Seroogy, Kim; Sortwell, Caryl; Steece-Collier, Kathy 09-30-2009 -07-31-2010 National Institute of Neurological Disorders and Stroke Aging and Parkinson's Disease: Models of Therapeutics and Neurologic Comorbidity Role:Collaborator $1,279,260.00 Closed Level:Federal

Grant: #3 R01 MH069725-05S1 Investigators:Herman, James; Jankord, Ryan 09-30-2009 -09-29-2010 National Institute of Mental Health Anatomical Plasticity and HPA Axis Dysfunction Role:PI $104,270.00 Closed Level:Federal

Grant: #K99 HL096830 Investigators:Herman, James; Krause, Eric; Sakai, Randall 09-15-2009 -07-31-2011 National Heart, Lung and Blood Institute Central AT1 Receptors and the Integrated Stress Response Role:Collaborator $248,089.00 Closed Level:Federal

Grant: #3 K23MH067705-05S1 Investigators:Geracioti, Thomas; Herman, James; Keck, Paul; McElroy, Susan Lynn; Nelson, Erik; Shukla, Rakesh; Strakowski, Stephen 07-01-2009 -06-30-2010 National Institute of Mental Health Hypothalamic-Pituitary-Adrenal Axis Dysregulation & Phenomenology of Major Depression ARRA Supplement Role:Collaborator $54,000.00 Closed Level:Federal

Grant: #F32 MH084515 Investigators:Herman, James; Jankord, Ryan 06-12-2009 -06-30-2010 National Institute of Mental Health Neurohypophysial Control of the Cytokine Stress Response Role:Collaborator $50,054.00 Completed Type:Grant

Grant: #R01 MH066958 / TUL-576-08/09 Investigators:Herman, James 02-10-2009 -12-31-2012 National Institute of Mental Health Acute Corticosteroid Actions in the Hypothalamus Role:PI $228,767.00 Closed Level:Federal

Grant: #R01 MH066958 Investigators:Tasker, Herman 2009 -2014 NIMH Acute Corticosteroid Actions in the Hypothalamus Role:co-PI (subcontract) $112,000 Completed Type:Contract

Grant: #P01 NS058830 Investigators:Collier, Seroogy, Herman 2009 -2012 NINDS Aging and Parkinson's Disease: Models of Therapeutics and Neurologic Comorbidity Role:mPI (project 4) Completed Type:Grant

Grant: #SRS 006006 Investigators:Herman, James; Seroogy, Kim 09-01-2008 -02-28-2010 Davis Phinney Foundation Effects of Exercise on Stress-Induced Dysfunction and Depression in a Model of Parkinson's Disease Role:Collaborator $53,000.00 Closed Level:Private Non-Profit

Grant: #1R21MH083192-01A1 Investigators:Benoit, Stephen; Gudelsky, Gary; Herman, James; Richtand, Neil; Stern, Javier 08-20-2008 -07-31-2011 National Institute of Mental Health Antipsychotics, Hypoglycemia, Glutamate and Cognition Role:Collaborator $386,100.00 Closed Level:Federal

Grant: #R01 DK066596 Investigators:Herman, James; Jandacek, Ronald; Johnson, Jeffrey; Sakai, Randall; Woods, Stephen 07-01-2008 -06-30-2013 National Inst of Diabetes and Digestive and Kidney Disease Stress and Body Weight Regulation Role:Collaborator $1,301,908.00 Completed Type:Grant

Grant: #R01 NS060114 Investigators:Herman, James; Lipton, Jack; Seroogy, Kim 06-01-2008 -05-31-2013 National Institute of Neurological Disorders and Stroke Stress-Induced Depression and Parkinsonian Symptomology Role:Collaborator $1,689,188.00 Completed Type:Grant

Grant: #R21 MH083213 Investigators:Herman, James; Sah, Renu 04-01-2008 -03-31-2011 National Institute of Mental Health Role of Novel PH-Sensing Receptor TDAG8 in Panic Role:Collaborator $374,291.00 Closed Level:Federal

Grant: #R01 MH049698 Investigators:Herman, James; Sakai, Randall 04-01-2008 -01-31-2014 National Institute of Mental Health Functional Anatomy of Limbic-Neuroendocrine Circuits Role:PI $1,716,734.00 Completed Type:Grant

Grant: #R01 NS060114 Investigators:Seroogy, Herman 2008 -2013 NINDS Stress-Induced Depression and Parkinsonian Symptomology Role:co-PI Completed Type:Grant

Grant: #R01 MH049698 Investigators:Herman 2008 -2013 NIMH Functional Anatomy of Limbic/Neuroendocrine Circuits Role:PI 1,125,000 Completed Type:Grant

Grant: #1 K01 DK078906-01 Investigators:Herman, James; Ulrich-Lai, Yvonne; Woods, Stephen 07-20-2007 -09-30-2012 National Inst of Diabetes and Digestive and Kidney Disease Palatable Food, Reward and Stress Role:Collaborator $615,786.00 Closed Level:Federal

Grant: #SRS 005190 Investigators:Herman, James; Seroogy, Kim 07-01-2007 -09-30-2008 Davis Phinney Foundation Evaluation of Pre-Existing Chronic Stress-Induced Depression on Behavioral Dysfunction and Dopaminergic Neuronal Degeneration in the Injured-- Role:Collaborator $50,000.00 Closed Level:Private Non-Profit

Grant: #R01-MH-069725 Investigators:Herman, James 04-08-2005 -03-31-2011 National Institute of Mental Health Anatomical Plasticity and Hypothalamo Pituitary Adrenocortical Axis Dysfunction Role:PI $1,819,393.00 Closed Level:Federal

Grant: #4-702546-05-223 / P01 AG10836 Investigators:Herman, James 09-01-2004 -08-31-2009 National Institute on Aging Calcium Regulation in Brain Aging and Alzheimer's Disease Role:PI $90,900.00 Closed Level:Federal

Grant: #R01-MH-069860 Investigators:Herman, James 12-01-2003 -11-30-2009 National Institute of Mental Health Brainstem Mechanisms of Stress Regulation Role:PI $1,656,394.00 Closed Level:Federal

Grant: #T32 NS007453 Investigators:Herman, James 07-01-2003 -06-30-2009 National Institute of Neurological Disorders and Stroke Predoctoral Training Program in the Neurosciences Role:PI $1,056,771.32 Closed Level:Federal

Grant: #R01-AG-12962 Investigators:Herman, James 06-01-2002 -05-31-2009 National Institute on Aging Glucocortoid Receptor Mechanisms, Stress and Aging Role:PI $1,816,073.00 Active Level:Federal

Grant: #5-R01-MH-49698-15-A0-S0-E0 Investigators:Herman, James 05-15-2002 -02-28-2007 National Institute of Mental Health Functional Anatomy of Limbic - Neuroendocrine Circuits Role:PI $1,685,419.00 Closed Level:Federal

Grant: #5-R01-MH-62456-05-A0-S0-E0 Investigators:Herman, James 07-01-2001 -06-30-2006 National Institute of Mental Health Corticosteroid Dependent Mechanisms of Stress Adaptation Role:PI $176,777.00 Closed Level:Federal

Investigators:Herman, James 09-21-2000 -08-31-2004 National Institute of Neurological Disorders and Stroke Activity-Dependent Plasticity of Neuroendocrine Axons Role:PI $106,466.00 Closed Level:Federal

Grant: #5-P01-AG-10836-10-A0-S0-E0 Investigators:Herman, James 09-01-2000 -11-30-2003 National Institute on Aging Calcium Regulation in Brain Aging and Alzheimer's Disease Role:PI $311,270.00 Closed Level:Federal

Grant: #PHARMUPJ-02-01-A0-S1-E1 Investigators:Herman, James 01-31-2000 -05-10-2001 Pharmacia & Upjohn Company Effects of Reboxetine on Central GABAergic Stress Integration Role:PI $35,419.00 Closed Level:Industry

Investigators:Herman, James 01-01-2000 -12-31-2002 National Science Foundation Mechanisms of Stress Regulation in the Female Role:PI $199,000.00 Closed Level:Federal

Grant: #5-R03-MH-60819-03-A0-S0-E0 Investigators:Herman, James 01-01-2000 -08-31-2003 National Institute of Mental Health Neurocircuits, HPA Dysfunction and Affective Disorder Role:PI $149,208.00 Closed Level:Federal

Grant: #7-R01-AG-12962-05-A0-S0-E0 Investigators:Herman, James 01-01-2000 -04-30-2001 National Institute on Aging Glucocoticoid Receptor Mechanisms, Stress and Aging Role:PI $107,473.00 Closed Level:Federal

Grant: #5-R01-MH-49698-10-A0-S0-E0 Investigators:Herman, James 01-01-2000 -05-14-2002 National Institute of Mental Health Functional Anatomy of Limbic-Neuroendocrine Circuits Role:PI $607,395.00 Closed Level:Federal

Grant: #VA Billing Agreement Nawreen sub VA Merit 5I01BX003858-03 Investigators:Herman, James; Nawreen, Nawshaba 07-01-2019 -06-30-2021 Department of Veterans Affairs VA IPA for Nawshaba Nawreen Role:PI $33,077.00 Awarded Level:Federal

Grant: #R01MH119814 Investigators:Herman, James; Song, Seongho; Ulrich-Lai, Yvonne; Wang, Xia 09-11-2019 -06-30-2024 National Institute of Mental Health Stress resilience by natural rewards: neurocircuit mechanisms Role:Collaborator $561,667.00 Awarded Level:Federal

Grant: #F31MH123041 Investigators:Herman, James; Nawreen, Nawshaba 06-01-2020 -05-31-2023 National Institute of Mental Health Assessing the role of Parvalbumin Interneurons in Adolescent Stress Induced Resilience Role:Collaborator $42,541.00 Awarded Level:Federal

Grant: #T32NS007453 Investigators:Baccei, Mark; Herman, James 07-01-2021 -06-30-2026 National Institute of Neurological Disorders and Stroke Predoctoral Training Program in the Neurosciences Role:PI 195900.00 Awarded Level:Federal

Grant: #W81XWH-21-1-0877 Investigators:Herman, James; Reyes, Teresa; Seroogy, Kim 09-01-2021 -08-31-2024 Department of the Army Medical Research Acquisition Activity PD200038: Stress/Glucocorticoid Mechanisms in Parkinsonian Pathologies Role:Collaborator 1200000.00 Awarded Level:Federal

Grant: #VA Billing Agreement Devine Investigators:Devine, Emily; Herman, James 09-01-2022 -08-31-2023 Department of Veterans Affairs VA Billing Agreement Devine Role:PI 32765.90 Hold Level:Federal

Grant: #R01MH127835 Investigators:Baccei, Mark; Herman, James 09-02-2022 -06-30-2027 National Institute of Mental Health Cortical Mechanisms of Traumatic Stress Role:PI 549020.00 Awarded Level:Federal

Grant: #UIA S04307-01 (R01MH132223) Investigators:Herman, James 06-01-2023 -03-31-2024 National Institute of Mental Health Circuit versus stress hormonal influences in consolidation of fear memory strength and precision Role:PI 36813.00 Awarded Level:Federal

Peer Reviewed Publications

Evanson, Nathan K; Tasker, Jeffrey G; Hill, Matthew N; Hillard, Cecilia J; Herman, James P (2010. ) Fast Feedback Inhibition of the HPA Axis by Glucocorticoids Is Mediated by Endocannabinoid Signaling.Endocrinology, , More Information

McGuire, Jennifer; Herman, James P; Horn, Paul S; Sallee, Floyd R; Sah, Renu (2010. ) Enhanced fear recall and emotional arousal in rats recovering from chronic variable stress.Physiology & behavior, , More Information

Evanson, N K; Herman, J P; Sakai, R R; Krause, E G (2010. ) Nongenomic actions of adrenal steroids in the central nervous system.Journal of neuroendocrinology, , 22 (8 ) ,846-61 More Information

Wulsin, Aynara C; Herman, James P; Solomon, Matia B (2010. ) Mifepristone decreases depression-like behavior and modulates neuroendocrine and central hypothalamic-pituitary-adrenocortical axis responsiveness to stress.Psychoneuroendocrinology, , 35 (7 ) ,1100-12 More Information

Jankord, Ryan; Zhang, Rong; Flak, Jonathan N; Solomon, Matia B; Albertz, Jennifer; Herman, James P (2010. ) Stress activation of IL-6 neurons in the hypothalamus.American journal of physiology. Regulatory, integrative and comparative physiology, , 299 (1 ) ,R343-51 More Information

Evanson, Nathan K; Van Hooren, Daniella C; Herman, James P (2009. ) GluR5-mediated glutamate signaling regulates hypothalamo-pituitary-adrenocortical stress responses at the paraventricular nucleus and median eminence.Psychoneuroendocrinology, , 34 (9 ) ,1370-9 More Information

Benoit, Stephen C; Kemp, Christopher J; Elias, Carol F; Abplanalp, William; Herman, James P; Migrenne, Stephanie; Lefevre, Anne-Laure; Cruciani-Guglielmacci, Céline; Magnan, Christophe; Yu, Fang; Niswender, Kevin; Irani, Boman G; Holland, William L; Clegg, Deborah J (2009. ) Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents.The Journal of clinical investigation, , 119 (9 ) ,2577-89 More Information

McGuire, Jennifer; Herman, James P; Ghosal, Sriparna; Eaton, Katherine; Sallee, Floyd R; Sah, Renu (2009. ) Acid-sensing by the T cell death-associated gene 8 (TDAG8) receptor cloned from rat brain.Biochemical and biophysical research communications, , 386 (3 ) ,420-5 More Information

Laroche, Julie; Gasbarro, Lauren; Herman, James P; Blaustein, Jeffrey D (2009. ) Enduring influences of peripubertal/adolescent stressors on behavioral response to estradiol and progesterone in adult female mice.Endocrinology, , 150 (8 ) ,3717-25 More Information

Ulrich-Lai, Yvonne M; Herman, James P (2009. ) Neural regulation of endocrine and autonomic stress responses.Nature reviews. Neuroscience, , 10 (6 ) ,397-409 More Information

Solomon, Matia B; Herman, James P (2009. ) Sex differences in psychopathology: of gonads, adrenals and mental illness.Physiology & behavior, , 97 (2 ) ,250-8 More Information

Ulrich-Lai, Yvonne M; Herman, James P (2009. ) Neural regulation of endocrine and autonomic stress responses.Nature reviews. Neuroscience, , More Information

Laroche, Julie; Gasbarro, Lauren; Herman, James P; Blaustein, Jeffrey D (2009. ) Reduced behavioral response to gonadal hormones in mice shipped during the peripubertal/adolescent period.Endocrinology, , 150 (5 ) ,2351-8 More Information

Kasckow, J; Xiao, C; Herman, J P (2009. ) Glial glucocorticoid receptors in aged Fisher 344 (F344) and F344/Brown Norway rats.Experimental gerontology, , 44 (5 ) ,335-43 More Information

Doczy, Erica J; Seroogy, Kim; Harrison, Catherine R; Herman, James P (2009. ) Hypothalamo-pituitary-adrenocortical axis, glucocorticoids, and neurologic disease.Immunology and allergy clinics of North America, , 29 (2 ) ,265-84 More Information

Zhang, Rong; Packard, Benjamin A; Tauchi, Miyuki; D'Alessio, David A; Herman, James P (2009. ) Glucocorticoid regulation of preproglucagon transcription and RNA stability during stress.Proceedings of the National Academy of Sciences of the United States of America, , 106 (14 ) ,5913-8 More Information

Herman, James P; Harwood, Mark R; Wallman, Josh (2009. ) Saccade adaptation specific to visual context.Journal of neurophysiology, , 101 (4 ) ,1713-21 More Information

Segar, Tracy M; Kasckow, John W; Welge, Jeffrey A; Herman, James P (2009. ) Heterogeneity of neuroendocrine stress responses in aging rat strains.Physiology & behavior, , 96 (1 ) ,6-11 More Information

Jankord, Ryan; Herman, James P (2008. ) Limbic regulation of hypothalamo-pituitary-adrenocortical function during acute and chronic stress.Annals of the New York Academy of Sciences, , 1148 ,64-73 More Information

Tauchi, Miyuki; Zhang, Rong; D'Alessio, David A; Stern, Javier E; Herman, James P (2008. ) Distribution of glucagon-like peptide-1 immunoreactivity in the hypothalamic paraventricular and supraoptic nuclei.Journal of chemical neuroanatomy, , 36 (3-4 ) ,144-9 More Information

Furay, Amy R; Bruestle, Amy E; Herman, James P (2008. ) The role of the forebrain glucocorticoid receptor in acute and chronic stress.Endocrinology, , 149 (11 ) ,5482-90 More Information

Cullinan, William E; Ziegler, Dana R; Herman, James P (2008. ) Functional role of local GABAergic influences on the HPA axis.Brain structure & function, , 213 (1-2 ) ,63-72 More Information

Bornstein, Stefan R; Engeland, William C; Ehrhart-Bornstein, Monika; Herman, James P (2008. ) Dissociation of ACTH and glucocorticoids.Trends in endocrinology and metabolism: TEM, , 19 (5 ) ,175-80 More Information

Choi, Dennis C; Furay, Amy R; Evanson, Nathan K; Ulrich-Lai, Yvonne M; Nguyen, Mary M N; Ostrander, Michelle M; Herman, James P (2008. ) The role of the posterior medial bed nucleus of the stria terminalis in modulating hypothalamic-pituitary-adrenocortical axis responsiveness to acute and chronic stress.Psychoneuroendocrinology, , 33 (5 ) ,659-69 More Information

Tauchi, Miyuki; Zhang, Rong; D'Alessio, David A; Seeley, Randy J; Herman, James P (2008. ) Role of central glucagon-like peptide-1 in hypothalamo-pituitary-adrenocortical facilitation following chronic stress.Experimental neurology, , 210 (2 ) ,458-66 More Information

Choi, Dennis C; Evanson, Nathan K; Furay, Amy R; Ulrich-Lai, Yvonne M; Ostrander, Michelle M; Herman, James P (2008. ) The anteroventral bed nucleus of the stria terminalis differentially regulates hypothalamic-pituitary-adrenocortical axis responses to acute and chronic stress.Endocrinology, , 149 (2 ) ,818-26 More Information

Herman, James P; Flak, Jonathan; Jankord, Ryan (2008. ) Chronic stress plasticity in the hypothalamic paraventricular nucleus.Progress in brain research, , 170 ,353-64 More Information

Jullien, Nicolas; Goddard, Isabelle; Selmi-Ruby, Samia; Fina, Jean-Luc; Cremer, Harold; Herman, Jean-Paul (2007. ) Conditional transgenesis using Dimerizable Cre (DiCre).PloS one, , 2 (12 ) ,e1355 More Information

Wortley, Katherine E; Garcia, Karen; Okamoto, Haruka; Thabet, Karen; Anderson, Keith D; Shen, Victor; Herman, Jim P; Valenzuela, David; Yancopoulos, George D; Tschöp, Matthias H; Murphy, Andrew; Sleeman, Mark W (2007. ) Peptide YY regulates bone turnover in rodents.Gastroenterology, , 133 (5 ) ,1534-43 More Information

Zhang, Hua; Herman, Jacob P; Bolton, Harvey; Zhang, Zhicheng; Clark, Sue; Xun, Luying (2007. ) Evidence that bacterial ABC-type transporter imports free EDTA for metabolism.Journal of bacteriology, , 189 (22 ) ,7991-7 More Information

Vahl, Torsten P; Tauchi, Miyuki; Durler, Timothy S; Elfers, Eileen E; Fernandes, Timothy M; Bitner, Ronald D; Ellis, Kay S; Woods, Stephen C; Seeley, Randy J; Herman, James P; D'Alessio, David A (2007. ) Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats.Endocrinology, , 148 (10 ) ,4965-73 More Information

Solomon, Jessica D; Case, Courtney L; Greiner, Jack V; Blackie, Caroline A; Herman, John P; Korb, Donald R (2007. ) Warm compress induced visual degradation and Fischer-Schweitzer polygonal reflex.Optometry and vision science : official publication of the American Academy of Optometry, , 84 (7 ) ,580-7 More Information

Figueiredo, Helmer F; Ulrich-Lai, Yvonne M; Choi, Dennis C; Herman, James P (2007. ) Estrogen potentiates adrenocortical responses to stress in female rats.American journal of physiology. Endocrinology and metabolism, , 292 (4 ) ,E1173-82 More Information

Ulrich-Lai, Yvonne M; Ostrander, Michelle M; Thomas, Ingrid M; Packard, Benjamin A; Furay, Amy R; Dolgas, C Mark; Van Hooren, Daniella C; Figueiredo, Helmer F; Mueller, Nancy K; Choi, Dennis C; Herman, James P (2007. ) Daily limited access to sweetened drink attenuates hypothalamic-pituitary-adrenocortical axis stress responses.Endocrinology, , 148 (4 ) ,1823-34 More Information

Cota, Daniela; Steiner, Michel-Alexander; Marsicano, Giovanni; Cervino, Cristina; Herman, James P; Grübler, Yvonne; Stalla, Johanna; Pasquali, Renato; Lutz, Beat; Stalla, Günter K; Pagotto, Uberto (2007. ) Requirement of cannabinoid receptor type 1 for the basal modulation of hypothalamic-pituitary-adrenal axis function.Endocrinology, , 148 (4 ) ,1574-81 More Information

Dent, Gersham; Choi, Dennis C; Herman, James P; Levine, Seymour (2007. ) GABAergic circuits and the stress hyporesponsive period in the rat: ontogeny of glutamic acid decarboxylase (GAD) 67 mRNA expression in limbic-hypothalamic stress pathways.Brain research, , 1138 ,1-9 More Information

Choi, Dennis C; Furay, Amy R; Evanson, Nathan K; Ostrander, Michelle M; Ulrich-Lai, Yvonne M; Herman, James P (2007. ) Bed nucleus of the stria terminalis subregions differentially regulate hypothalamic-pituitary-adrenal axis activity: implications for the integration of limbic inputs.The Journal of neuroscience : the official journal of the Society for Neuroscience, , 27 (8 ) ,2025-34 More Information

Herman, James P; Mueller, Nancy K (2006. ) Role of the ventral subiculum in stress integration.Behavioural brain research, , 174 (2 ) ,215-24 More Information

Ulrich-Lai, Yvonne M; Figueiredo, Helmer F; Ostrander, Michelle M; Choi, Dennis C; Engeland, William C; Herman, James P (2006. ) Chronic stress induces adrenal hyperplasia and hypertrophy in a subregion-specific manner.American journal of physiology. Endocrinology and metabolism, , 291 (5 ) ,E965-73 More Information

Choi, Dennis C; Nguyen, Mary M N; Tamashiro, Kellie L K; Ma, Li Yun; Sakai, Randall R; Herman, James P (2006. ) Chronic social stress in the visible burrow system modulates stress-related gene expression in the bed nucleus of the stria terminalis.Physiology & behavior, , 89 (3 ) ,301-10 More Information

Mueller, Nancy K; Dolgas, C Mark; Herman, James P (2006. ) Regulation of forebrain GABAergic stress circuits following lesion of the ventral subiculum.Brain research, , 1116 (1 ) ,132-42 More Information

Furay, A R; Murphy, E K; Mattson, M P; Guo, Z; Herman, J P (2006. ) Region-specific regulation of glucocorticoid receptor/HSP90 expression and interaction in brain.Journal of neurochemistry, , 98 (4 ) ,1176-84 More Information

Herman, James P; Seroogy, Kim (2006. ) Hypothalamic-pituitary-adrenal axis, glucocorticoids, and neurologic disease.Neurologic clinics, , 24 (3 ) ,461-81, vi More Information

McQuade, Jill M Slane; Tamashiro, Kellie L K; Wood, Gwendolyn E; Herman, James P; McEwen, Bruce S; Sakai, Randall R; Zhang, Jianhua; Xu, Ming (2006. ) Deficient hippocampal c-fos expression results in reduced anxiety and altered response to chronic stress in female mice.Neuroscience letters, , 403 (1-2 ) ,125-30 More Information

Ulrich-Lai, Yvonne M; Xie, Wenrui; Meij, Johanna T A; Dolgas, C Mark; Yu, Lei; Herman, James P (2006. ) Limbic and HPA axis function in an animal model of chronic neuropathic pain.Physiology & behavior, , 88 (1-2 ) ,67-76 More Information

Ostrander, Michelle M; Ulrich-Lai, Yvonne M; Choi, Dennis C; Richtand, Neil M; Herman, James P (2006. ) Hypoactivity of the hypothalamo-pituitary-adrenocortical axis during recovery from chronic variable stress.Endocrinology, , 147 (4 ) ,2008-17 More Information

Xiao, C; Sartin, J; Mulchahey, J J; Segar, T; Sheriff, S; Herman, J P; Kasckow, J W (2006. ) Aging associated changes in amygdalar corticotropin-releasing hormone (CRH) and CRH-binding protein in Fischer 344 rats.Brain research, , 1073-1074 ,325-31 More Information

Richtand, Neil M; Taylor, Benjamin; Welge, Jeffrey A; Ahlbrand, Rebecca; Ostrander, Michelle M; Burr, Jeffrey; Hayes, Scott; Coolen, Lique M; Pritchard, Laurel M; Logue, Aaron; Herman, James P; McNamara, Robert K (2006. ) Risperidone pretreatment prevents elevated locomotor activity following neonatal hippocampal lesions.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, , 31 (1 ) ,77-89 More Information

Girotti, M; Pace, T W W; Gaylord, R I; Rubin, B A; Herman, J P; Spencer, R L (2006. ) Habituation to repeated restraint stress is associated with lack of stress-induced c-fos expression in primary sensory processing areas of the rat brain.Neuroscience, , 138 (4 ) ,1067-81 More Information

Herman, James P; Ostrander, Michelle M; Mueller, Nancy K; Figueiredo, Helmer (2005. ) Limbic system mechanisms of stress regulation: hypothalamo-pituitary-adrenocortical axis.Progress in neuro-psychopharmacology & biological psychiatry, , 29 (8 ) ,1201-13 More Information

Vahl, Torsten P; Ulrich-Lai, Yvonne M; Ostrander, Michelle M; Dolgas, C Mark; Elfers, Eileen E; Seeley, Randy J; D'Alessio, David A; Herman, James P (2005. ) Comparative analysis of ACTH and corticosterone sampling methods in rats.American journal of physiology. Endocrinology and metabolism, , 289 (5 ) ,E823-8 More Information

Kasckow, John W; Segar, Tracy M; Xiao, Chun; Furay, Amy R; Evanson, Nathan K; Ostrander, Michelle M; Herman, James P (2005. ) Stability of neuroendocrine and behavioral responsiveness in aging Fischer 344/Brown-Norway hybrid rats.Endocrinology, , 146 (7 ) ,3105-12 More Information

Becker, Jill B; Arnold, Arthur P; Berkley, Karen J; Blaustein, Jeffrey D; Eckel, Lisa A; Hampson, Elizabeth; Herman, James P; Marts, Sherry; Sadee, Wolfgang; Steiner, Meir; Taylor, Jane; Young, Elizabeth (2005. ) Strategies and methods for research on sex differences in brain and behavior.Endocrinology, , 146 (4 ) ,1650-73 More Information

Ziegler, Dana R; Cullinan, William E; Herman, James P (2005. ) Organization and regulation of paraventricular nucleus glutamate signaling systems: N-methyl-D-aspartate receptors.The Journal of comparative neurology, , 484 (1 ) ,43-56 More Information

Mueller, Nancy K; Di, Shi; Paden, Charles M; Herman, James P (2005. ) Activity-dependent modulation of neurotransmitter innervation to vasopressin neurons of the supraoptic nucleus.Endocrinology, , 146 (1 ) ,348-54 More Information

Sah, R; Pritchard, L M; Richtand, N M; Ahlbrand, R; Eaton, K; Sallee, F R; Herman, J P (2005. ) Expression of the glucocorticoid-induced receptor mRNA in rat brain.Neuroscience, , 133 (1 ) ,281-92 More Information

Mueller, Nancy K; Dolgas, C Mark; Herman, James P (2004. ) Stressor-selective role of the ventral subiculum in regulation of neuroendocrine stress responses.Endocrinology, , 145 (8 ) ,3763-8 More Information

Herman, James P; Mueller, Nancy K; Figueiredo, Helmer (2004. ) Role of GABA and glutamate circuitry in hypothalamo-pituitary-adrenocortical stress integration.Annals of the New York Academy of Sciences, , 1018 ,35-45 More Information

Figueiredo, Helmer F; Bodie, Bryan L; Tauchi, Miyuki; Dolgas, C Mark; Herman, James P (2003. ) Stress integration after acute and chronic predator stress: differential activation of central stress circuitry and sensitization of the hypothalamo-pituitary-adrenocortical axis.Endocrinology, , 144 (12 ) ,5249-58 More Information

Ostrander, Michelle M; Richtand, Neil M; Herman, James P (2003. ) Stress and amphetamine induce Fos expression in medial prefrontal cortex neurons containing glucocorticoid receptors. Brain research, , 990 (1-2 ) ,209-14

Jullien, Nicolas; Sampieri, François; Enjalbert, Alain; Herman, Jean-Paul (2003. ) Regulation of Cre recombinase by ligand-induced complementation of inactive fragments. Nucleic acids research, , 31 (21 ) ,e131

Figueiredo, Helmer F; Bruestle, Amy; Bodie, Bryan; Dolgas, Charles M; Herman, James P (2003. ) The medial prefrontal cortex differentially regulates stress-induced c-fos expression in the forebrain depending on type of stressor. The European journal of neuroscience, , 18 (8 ) ,2357-64

Kinzig, Kimberly P; D'Alessio, David A; Herman, James P; Sakai, Randall R; Vahl, Torsten P; Figueiredo, Helmer F; Murphy, Erin K; Seeley, Randy J; Figueredo, Helmer F (2003. ) CNS glucagon-like peptide-1 receptors mediate endocrine and anxiety responses to interoceptive and psychogenic stressors. The Journal of neuroscience : the official journal of the Society for Neuroscience, , 23 (15 ) ,6163-70

Herman, James P; Figueiredo, Helmer; Mueller, Nancy K; Ulrich-Lai, Yvonne; Ostrander, Michelle M; Choi, Dennis C; Cullinan, William E (2003. ) Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness. Frontiers in neuroendocrinology, , 24 (3 ) ,151-80

Kasckow, J W; Aguilera, G; Mulchahey, J J; Sheriff, S; Herman, J P (2003. ) In vitro regulation of corticotropin-releasing hormone. Life sciences, , 73 (6 ) ,769-81

Kasckow, J; Mulchahey, J J; Aguilera, G; Pisarska, M; Nikodemova, M; Chen, H-C; Herman, J P; Murphy, E K; Liu, Y; Rizvi, T A; Dautzenberg, F M; Sheriff, S (2003. ) Corticotropin-releasing hormone (CRH) expression and protein kinase A mediated CRH receptor signalling in an immortalized hypothalamic cell line. Journal of neuroendocrinology, , 15 (5 ) ,521-9

Blalock, Eric M; Chen, Kuey-Chu; Sharrow, Keith; Herman, James P; Porter, Nada M; Foster, Thomas C; Landfield, Philip W (2003. ) Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment. The Journal of neuroscience : the official journal of the Society for Neuroscience, , 23 (9 ) ,3807-19

Herman, James P; Renda, Andrew; Bodie, Bryan (2003. ) Norepinephrine-gamma-aminobutyric acid (GABA) interaction in limbic stress circuits: effects of reboxetine on GABAergic neurons. Biological psychiatry, , 53 (2 ) ,166-74

McCullers, Deanna L; Sullivan, Patrick G; Scheff, Stephen W; Herman, James P (2002. ) Traumatic brain injury regulates adrenocorticosteroid receptor mRNA levels in rat hippocampus. Brain research, , 947 (1 ) ,41-9

Herman, James P; Cullinan, William E; Ziegler, Dana R; Tasker, Jeffrey G (2002. ) Role of the paraventricular nucleus microenvironment in stress integration. The European journal of neuroscience, , 16 (3 ) ,381-5

Figueiredo, Helmer F; Dolgas, Charles M; Herman, James P (2002. ) Stress activation of cortex and hippocampus is modulated by sex and stage of estrus. Endocrinology, , 143 (7 ) ,2534-40

Ziegler, Dana R; Cullinan, William E; Herman, James P (2002. ) Distribution of vesicular glutamate transporter mRNA in rat hypothalamus.The Journal of comparative neurology, , 448 (3 ) ,217-29 More Information

Murphy, Erin K; Spencer, Robert L; Sipe, Kimberly J; Herman, James P (2002. ) Decrements in nuclear glucocorticoid receptor (GR) protein levels and DNA binding in aged rat hippocampus. Endocrinology, , 143 (4 ) ,1362-70

Herman, James P; Tasker, Jeffrey G; Ziegler, Dana R; Cullinan, William E (2002. ) Local circuit regulation of paraventricular nucleus stress integration: glutamate-GABA connections. Pharmacology, biochemistry, and behavior, , 71 (3 ) ,457-68

Greiner, Jack V; Finnemore, Victor M; Exford, Joan M; Herman, John P; Glonek, Thomas; Bueno, Eleanor A; Korb, Donald R (2002. ) Effects of fluorescein instillation methods on the tear film lipid layer. Advances in experimental medicine and biology, , 506 (Pt A ) ,507-12

McCullers, D L; Sullivan, P G; Scheff, S W; Herman, J P (2002. ) Mifepristone protects CA1 hippocampal neurons following traumatic brain injury in rat. Neuroscience, , 109 (2 ) ,219-30

Wang, D; Herman, J P; Pritchard, L M; Spitzer, R H; Ahlbrand, R L; Kramer, G L; Petty, F; Sallee, F R; Richtand, N M (2001. ) Cloning, expression, and regulation of a glucocorticoid-induced receptor in rat brain: effect of repetitive amphetamine. The Journal of neuroscience : the official journal of the Society for Neuroscience, , 21 (22 ) ,9027-35

Herman, J P; Larson, B R (2001. ) Differential regulation of forebrain glutamic acid decarboxylase mRNA expression by aging and stress. Brain research, , 912 (1 ) ,60-6

Grinevich, V; Ma, X M; Herman, J P; Jezova, D; Akmayev, I; Aguilera, G (2001. ) Effect of repeated lipopolysaccharide administration on tissue cytokine expression and hypothalamic-pituitary-adrenal axis activity in rats. Journal of neuroendocrinology, , 13 (8 ) ,711-23

Pedersen, W A; McCullers, D; Culmsee, C; Haughey, N J; Herman, J P; Mattson, M P (2001. ) Corticotropin-releasing hormone protects neurons against insults relevant to the pathogenesis of Alzheimer's disease.Neurobiology of disease, , 8 (3 ) ,492-503 More Information

McCullers, D L; Herman, J P (2001. ) Adrenocorticosteroid receptor blockade and excitotoxic challenge regulate adrenocorticosteroid receptor mRNA levels in hippocampus. Journal of neuroscience research, , 64 (3 ) ,277-83

Herman, J P; Larson, B R; Speert, D B; Seasholtz, A F (2001. ) Hypothalamo-pituitary-adrenocortical dysregulation in aging F344/Brown-Norway F1 hybrid rats. Neurobiology of aging, , 22 (2 ) ,323-32

Langub, M C; Herman, J P; Malluche, H H; Koszewski, N J (2001. ) Evidence of functional vitamin D receptors in rat hippocampus. Neuroscience, , 104 (1 ) ,49-56

Ziegler, D R; Herman, J P (2000. ) Local integration of glutamate signaling in the hypothalamic paraventricular region: regulation of glucocorticoid stress responses. Endocrinology, , 141 (12 ) ,4801-4

Lee, J; Herman, J P; Mattson, M P (2000. ) Dietary restriction selectively decreases glucocorticoid receptor expression in the hippocampus and cerebral cortex of rats.Experimental neurology, , 166 (2 ) ,435-41 More Information

Paskitti, M E; McCreary, B J; Herman, J P (2000. ) Stress regulation of adrenocorticosteroid receptor gene transcription and mRNA expression in rat hippocampus: time-course analysis. Brain research. Molecular brain research, , 80 (2 ) ,142-52

Herman, J P; Eyigor, O; Ziegler, D R; Jennes, L (2000. ) Expression of ionotropic glutamate receptor subunit mRNAs in the hypothalamic paraventricular nucleus of the rat. The Journal of comparative neurology, , 422 (3 ) ,352-62

Becq, H; Bosler, O; Geffard, M; Enjalbert, A; Herman, J P (1999. ) Anatomical and functional reconstruction of the nigrostriatal system in vitro: selective innervation of the striatum by dopaminergic neurons. Journal of neuroscience research, , 58 (4 ) ,553-66

Kame, G Y.; Abo, J T.; Kame, R T.; Edrington, T B.; Herman, J P.; Matsuda, L K.; De Land, P (1999. ) The incidence of glassy corneal striae. International contact lens clinic (New York, N.Y.), , 26 (6 ) ,147-151

Emmert, M H; Herman, J P (1999. ) Differential forebrain c-fos mRNA induction by ether inhalation and novelty: evidence for distinctive stress pathways. Brain research, , 845 (1 ) ,60-7

Zhou, X; Herman, J P; Paden, C M (1999. ) Evidence that IGF-I acts as an autocrine/paracrine growth factor in the magnocellular neurosecretory system: neuronal synthesis and induction of axonal sprouting.Experimental neurology, , 159 (2 ) ,419-32 More Information

Herman, J P; Watson, S J; Spencer, R L (1999. ) Defense of adrenocorticosteroid receptor expression in rat hippocampus: effects of stress and strain. Endocrinology, , 140 (9 ) ,3981-91

Pedersen, W A; Culmsee, C; Ziegler, D; Herman, J P; Mattson, M P (1999. ) Aberrant stress response associated with severe hypoglycemia in a transgenic mouse model of Alzheimer's disease.Journal of molecular neuroscience : MN, , 13 (1-2 ) ,159-65 More Information

Ziegler, D R; Cass, W A; Herman, J P (1999. ) Excitatory influence of the locus coeruleus in hypothalamic-pituitary-adrenocortical axis responses to stress. Journal of neuroendocrinology, , 11 (5 ) ,361-9

Watt, J A; Moffet, C W; Zhou, X; Short, S; Herman, J P; Paden, C M (1999. ) Central peptidergic neurons are hyperactive during collateral sprouting and inhibition of activity suppresses sprouting. The Journal of neuroscience : the official journal of the Society for Neuroscience, , 19 (5 ) ,1586-98

Herman, J P; Chen, K C; Booze, R; Landfield, P W (1998. ) Up-regulation of alpha1D Ca2+ channel subunit mRNA expression in the hippocampus of aged F344 rats. Neurobiology of aging, , 19 (6 ) ,581-7

Herman, J P; Spencer, R (1998. ) Regulation of hippocampal glucocorticoid receptor gene transcription and protein expression in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience, , 18 (18 ) ,7462-73

McCullers, D L; Herman, J P (1998. ) Mineralocorticoid receptors regulate bcl-2 and p53 mRNA expression in hippocampus. Neuroreport, , 9 (13 ) ,3085-9

Prewitt, C M; Herman, J P (1998. ) Anatomical interactions between the central amygdaloid nucleus and the hypothalamic paraventricular nucleus of the rat: a dual tract-tracing analysis. Journal of chemical neuroanatomy, , 15 (3 ) ,173-85

Herman, J P; Dolgas, C M; Carlson, S L (1998. ) Ventral subiculum regulates hypothalamo-pituitary-adrenocortical and behavioural responses to cognitive stressors. Neuroscience, , 86 (2 ) ,449-59

Bowers, G; Cullinan, W E; Herman, J P (1998. ) Region-specific regulation of glutamic acid decarboxylase (GAD) mRNA expression in central stress circuits. The Journal of neuroscience : the official journal of the Society for Neuroscience, , 18 (15 ) ,5938-47

Prewitt, ; Herman, (1997. ) Hypothalamo-Pituitary-Adrenocortical Regulation Following Lesions of the Central Nucleus of the Amygdala. Stress (Amsterdam, Netherlands), , 1 (4 ) ,263-280

Zhou, X; Herman, J P; Paden, C M (1997. ) Expression of insulin-like growth factor binding protein-2 during postnatal development of the rat neurointermediate pituitary. Neuroendocrinology, , 66 (1 ) ,17-27

Herman, J P; Cullinan, W E (1997. ) Neurocircuitry of stress: central control of the hypothalamo-pituitary-adrenocortical axis. Trends in neurosciences, , 20 (2 ) ,78-84

Herman, J P; Dolgas, C M; Marcinek, R; Langub, M C (1996. ) Expression and glucocorticoid regulation of natriuretic peptide clearance receptor (NPR-C) mRNA in rat brain and choroid plexus. Journal of chemical neuroanatomy, , 11 (4 ) ,257-65

Herman, J P; Morrison, D G (1996. ) Immunoautoradiographic and in situ hybridization analysis of corticotropin-releasing hormone biosynthesis in the hypothalamic paraventricular nucleus. Journal of chemical neuroanatomy, , 11 (1 ) ,49-56

Herman, J P; Dolgas, C M; Rucker, D; Langub, M C (1996. ) Localization of natriuretic peptide-activated guanylate cyclase mRNAs in the rat brain.The Journal of comparative neurology, , 369 (2 ) ,165-87 More Information

Herman, J P; Prewitt, C M; Cullinan, W E (1996. ) Neuronal circuit regulation of the hypothalamo-pituitary-adrenocortical stress axis. Critical reviews in neurobiology, , 10 (3-4 ) ,371-94

Herman, J P (1995. ) In situ hybridization analysis of vasopressin gene transcription in the paraventricular and supraoptic nuclei of the rat: regulation by stress and glucocorticoids.The Journal of comparative neurology, , 363 (1 ) ,15-27 More Information

Herman, J P; Cullinan, W E; Morano, M I; Akil, H; Watson, S J (1995. ) Contribution of the ventral subiculum to inhibitory regulation of the hypothalamo-pituitary-adrenocortical axis. Journal of neuroendocrinology, , 7 (6 ) ,475-82

Langub, M C; Watson, R E; Herman, J P (1995. ) Distribution of natriuretic peptide precursor mRNAs in the rat brain.The Journal of comparative neurology, , 356 (2 ) ,183-99 More Information

Herman, J P; Watson, S J (1995. ) Stress regulation of mineralocorticoid receptor heteronuclear RNA in rat hippocampus. Brain research, , 677 (2 ) ,243-9

Numan, S; Lundgren, K H; Wright, D E; Herman, J P; Seroogy, K B (1995. ) Increased expression of 5HT2 receptor mRNA in rat striatum following 6-OHDA lesions of the adult nigrostriatal pathway. Brain research. Molecular brain research, , 29 (2 ) ,391-6

Langub, M C; Dolgas, C M; Watson, R E; Herman, J P (1995. ) The C-type natriuretic peptide receptor is the predominant natriuretic peptide receptor mRNA expressed in rat hypothalamus. Journal of neuroendocrinology, , 7 (4 ) ,305-9

Herman, J P; Adams, D; Prewitt, C (1995. ) Regulatory changes in neuroendocrine stress-integrative circuitry produced by a variable stress paradigm. Neuroendocrinology, , 61 (2 ) ,180-90

Cullinan, W E; Herman, J P; Battaglia, D F; Akil, H; Watson, S J (1995. ) Pattern and time course of immediate early gene expression in rat brain following acute stress. Neuroscience, , 64 (2 ) ,477-505

Herman, J P; Watson, S J (1994. ) Glucocorticoid regulation of stress-induced mineralocorticoid receptor gene transcription in vivo. Annals of the New York Academy of Sciences, , 746 ,485-8

Prewitt, C M; Herman, J P (1994. ) Lesion of the central nucleus of the amygdala decreases basal CRH mRNA expression and stress-induced ACTH release. Annals of the New York Academy of Sciences, , 746 ,438-40

Herman, J P; Cullinan, W E; Watson, S J (1994. ) Involvement of the bed nucleus of the stria terminalis in tonic regulation of paraventricular hypothalamic CRH and AVP mRNA expression. Journal of neuroendocrinology, , 6 (4 ) ,433-42

Keegan, C E; Herman, J P; Karolyi, I J; O'Shea, K S; Camper, S A; Seasholtz, A F (1994. ) Differential expression of corticotropin-releasing hormone in developing mouse embryos and adult brain. Endocrinology, , 134 (6 ) ,2547-55

Herman, J P; Langub, M C; Watson, R E (1993. ) Localization of C-type natriuretic peptide mRNA in rat hypothalamus. Endocrinology, , 133 (4 ) ,1903-6

Herman, J P (1993. ) Regulation of adrenocorticosteroid receptor mRNA expression in the central nervous system. Cellular and molecular neurobiology, , 13 (4 ) ,349-72

Herman, J P; Sherman, T G (1993. ) Acute stress upregulates vasopressin gene expression in parvocellular neurons of the hypothalamic paraventricular nucleus. Annals of the New York Academy of Sciences, , 689 ,546-9

Cullinan, W E; Herman, J P; Watson, S J (1993. ) Ventral subicular interaction with the hypothalamic paraventricular nucleus: evidence for a relay in the bed nucleus of the stria terminalis.The Journal of comparative neurology, , 332 (1 ) ,1-20 More Information

Herman, J P; Watson, S J; Chao, H M; Coirini, H; McEwen, B S (1993. ) Diurnal Regulation of Glucocorticoid Receptor and Mineralocorticoid Receptor mRNAs in Rat Hippocampus.Molecular and cellular neurosciences, , 4 (2 ) ,181-90 More Information

Herman, J P; Cullinan, W E; Young, E A; Akil, H; Watson, S J (1992. ) Selective forebrain fiber tract lesions implicate ventral hippocampal structures in tonic regulation of paraventricular nucleus corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) mRNA expression. Brain research, , 592 (1-2 ) ,228-38

Herman, J P; Schafer, M K; Thompson, R C; Watson, S J (1992. ) Rapid regulation of corticotropin-releasing hormone gene transcription in vivo. Molecular endocrinology (Baltimore, Md.), , 6 (7 ) ,1061-9

Herman, J P; Schäfer, M K; Watson, S J; Sherman, T G (1991. ) In situ hybridization analysis of arginine vasopressin gene transcription using intron-specific probes. Molecular endocrinology (Baltimore, Md.), , 5 (10 ) ,1447-56

Ford-Holevinski, T S; Castle, M R; Herman, J P; Watson, S J (1991. ) Microcomputer-based three-dimensional reconstruction of in situ hybridization autoradiographs. Journal of chemical neuroanatomy, , 4 (5 ) ,373-85

Herman, J P; Thomas, G J; Wiegand, S J; Gash, D M (1991. ) Lesions of parvocellular subdivisions of the hypothalamic paraventricular nucleus alter open field behavior and acquisition of sensory and spatial discrimination. Brain research, , 550 (2 ) ,291-7

Herman, J P; McKlveen, J M; Solomon, M B; Carvalho-Netto, E; Myers, B (2012. ) Neural regulation of the stress response: glucocorticoid feedback mechanisms. Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], , 45 (4 ) ,292-8

Herman, J P; Wiegand, S J; Watson, S J (1990. ) Regulation of basal corticotropin-releasing hormone and arginine vasopressin messenger ribonucleic acid expression in the paraventricular nucleus: effects of selective hypothalamic deafferentations. Endocrinology, , 127 (5 ) ,2408-17

Ryan, Karen K; Grayson, Bernadette E; Jones, Kenneth R; Schneider, Alexander L; Woods, Stephen C; Seeley, Randy J; Herman, James P; Ulrich-Lai, Yvonne M (2012. ) Physiological responses to acute psychological stress are reduced by the PPAR? agonist rosiglitazone.Endocrinology, , 153 (3 ) ,1279-87 More Information

Solomon, M B; Furay, A R; Jones, K; Packard, A E B; Packard, B A; Wulsin, A C; Herman, J P (2012. ) Deletion of forebrain glucocorticoid receptors impairs neuroendocrine stress responses and induces depression-like behavior in males but not females.Neuroscience, , 203 ,135-43 More Information

Myers, Brent; McKlveen, Jessica M; Herman, James P (2012. ) Neural Regulation of the Stress Response: The Many Faces of Feedback.Cellular and molecular neurobiology, , More Information

Herman, James P; Lindquist, Diana; Komoroski, Richard A (2012. ) Linking cerebral metabolic function to stress vulnerability (Commentary on Knapman et al.).The European journal of neuroscience, , 35 (3 ) ,411 More Information

Ziegler, Dana R; Edwards, Monica R; Ulrich-Lai, Yvonne M; Herman, James P; Cullinan, William E (2012. ) Brainstem origins of glutamatergic innervation of the rat hypothalamic paraventricular nucleus.The Journal of comparative neurology, , More Information

Herman, J P; Schäfer, K H; Sladek, C D; Day, R; Young, E A; Akil, H; Watson, S J (1989. ) Chronic electroconvulsive shock treatment elicits up-regulation of CRF and AVP mRNA in select populations of neuroendocrine neurons. Brain research, , 501 (2 ) ,235-46

Herman, James P (2012. ) Introduction: stress and neurological disease.Experimental neurology, , 233 (1 ) ,1-2 More Information

Herman, J P; Patel, P D; Akil, H; Watson, S J (1989. ) Localization and regulation of glucocorticoid and mineralocorticoid receptor messenger RNAs in the hippocampal formation of the rat. Molecular endocrinology (Baltimore, Md.), , 3 (11 ) ,1886-94

Nahar, Jebun; Haam, Juhee; Chen, Chun; Jiang, Zhiying; Glatzer, Nicholas R; Muglia, Louis J; Dohanich, Gary P; Herman, James P; Tasker, Jeffrey G (2015. ) Rapid Nongenomic Glucocorticoid Actions in Male Mouse Hypothalamic Neuroendocrine Cells Are Dependent on the Nuclear Glucocorticoid Receptor.Endocrinology, , 156 (8 ) ,2831-42 More Information

Herman, J P; Schäfer, M K; Young, E A; Thompson, R; Douglass, J; Akil, H; Watson, S J (1989. ) Evidence for hippocampal regulation of neuroendocrine neurons of the hypothalamo-pituitary-adrenocortical axis. The Journal of neuroscience : the official journal of the Society for Neuroscience, , 9 (9 ) ,3072-82

Solomon, Matia B; Loftspring, Matthew; de Kloet, Annette D; Ghosal, Sriparna; Jankord, Ryan; Flak, Jonathan N; Wulsin, Aynara C; Krause, Eric G; Zhang, Rong; Rice, Taylor; McKlveen, Jessica; Myers, Brent; Tasker, Jeffrey G; Herman, James P (2015. ) Neuroendocrine Function After Hypothalamic Depletion of Glucocorticoid Receptors in Male and Female Mice.Endocrinology, , 156 (8 ) ,2843-53 More Information

Shea, Chloe J A; Carhuatanta, Kimberly A K; Wagner, Jessica; Bechmann, Naomi; Moore, Raquel; Herman, James P; Jankord, Ryan (2015. ) Variable impact of chronic stress on spatial learning and memory in BXD mice.Physiology & behavior, , More Information

Ghosal, Sriparna; Nunley, Amanda; Mahbod, Parinaz; Lewis, Alfor G; Smith, Eric P; Tong, Jenny; D'Alessio, David A; Herman, James P (2015. ) Mouse handling limits the impact of stress on metabolic endpoints.Physiology & behavior, , More Information

McKlveen, J M; Myers, B; Herman, J P (2015. ) The medial prefrontal cortex: coordinator of autonomic, neuroendocrine and behavioural responses to stress.Journal of neuroendocrinology, , 27 (6 ) ,446-56 More Information

de Kloet, Annette D; Krause, Eric G; Solomon, Matia B; Flak, Jonathan N; Scott, Karen A; Kim, Dong-Hoon; Myers, Brent; Ulrich-Lai, Yvonne M; Woods, Stephen C; Seeley, Randy J; Herman, James P (2015. ) Adipocyte glucocorticoid receptors mediate fat-to-brain signaling.Psychoneuroendocrinology, , 56 ,110-9 More Information

Arble, Deanna M; Holland, Jenna; Ottaway, Nickki; Sorrell, Joyce; Pressler, Joshua W; Morano, Rachel; Woods, Stephen C; Seeley, Randy J; Herman, James P; Sandoval, Darleen A; Perez-Tilve, Diego (2015. ) The melanocortin-4 receptor integrates circadian light cues and metabolism.Endocrinology, , 156 (5 ) ,1685-91 More Information

Makinson, Ryan; Lundgren, Kerstin H; Seroogy, Kim B; Herman, James P (2015. ) Chronic social subordination stress modulates glutamic acid decarboxylase (GAD) 67 mRNA expression in central stress circuits.Physiology & behavior, , More Information

Bundzikova-Osacka, Jana; Ghosal, Sriparna; Packard, Benjamin A; Ulrich-Lai, Yvonne M; Herman, James P (2015. ) Role of nucleus of the solitary tract noradrenergic neurons in post-stress cardiovascular and hormonal control in male rats.Stress (Amsterdam, Netherlands), , 18 (2 ) ,221-32 More Information

Herman, J P; Marciano, F F; Wiegand, S J; Gash, D M (1987. ) Selective cell death of magnocellular vasopressin neurons in neurohypophysectomized rats following chronic administration of vasopressin. The Journal of neuroscience : the official journal of the Society for Neuroscience, , 7 (8 ) ,2564-75

Evanson, Nathan K; Herman, James P (2015. ) Metabotropic glutamate receptor-mediated signaling dampens the HPA axis response to restraint stress.Physiology & behavior, , More Information

Woods, Stephen C; Herman, James P (2015. ) Brain insulin receptors link stress and metabolism.Molecular metabolism, , 4 (2 ) ,77-8 More Information

Grayson, Bernadette E; Hakala-Finch, Andrew P; Kekulawala, Melani; Laub, Holly; Egan, Ann E; Ressler, Ilana B; Woods, Stephen C; Herman, James P; Seeley, Randy J; Benoit, Stephen C; Ulrich-Lai, Yvonne M (2014. ) Weight loss by calorie restriction versus bariatric surgery differentially regulates the hypothalamo-pituitary-adrenocortical axis in male rats.Stress (Amsterdam, Netherlands), , 17 (6 ) ,484-93 More Information

Herman, J P; Marciano, F F; Gash, D M (1986. ) Vasopressin administration prevents functional recovery of the vasopressinergic neurosecretory system following neurohypophysectomy. Neuroscience letters, , 72 (3 ) ,239-46

Uchoa, E T; Aguilera, G; Herman, J P; Fiedler, J L; Deak, T; de Sousa, M B C (2014. ) Novel aspects of glucocorticoid actions.Journal of neuroendocrinology, , 26 (9 ) ,557-72 More Information

Herman, J P; Wiegand, S J (1986. ) Ibotenate-induced cell death in the hypothalamic paraventricular nucleus: differential susceptibility of magnocellular and parvicellular neurons. Brain research, , 383 (1-2 ) ,367-72

Packard, Amy E B; Ghosal, Sriparna; Herman, James P; Woods, Stephen C; Ulrich-Lai, Yvonne M (2014. ) Chronic variable stress improves glucose tolerance in rats with sucrose-induced prediabetes.Psychoneuroendocrinology, , 47 ,178-88 More Information

Myers, Brent; Mark Dolgas, C; Kasckow, John; Cullinan, William E; Herman, James P (2014. ) Central stress-integrative circuits: forebrain glutamatergic and GABAergic projections to the dorsomedial hypothalamus, medial preoptic area, and bed nucleus of the stria terminalis.Brain structure & function, , 219 (4 ) ,1287-303 More Information

Herman, J P; Thomas, G J; Gash, D M (1986. ) Behavioral characteristics of Roman high avoidance rats homozygous for diabetes insipidus (RHA: di/di). Behavioural brain research, , 20 (1 ) ,27-38

Ghosal, Sriparna; Bundzikova-Osacka, Jana; Dolgas, C Mark; Myers, Brent; Herman, James P (2014. ) Glucocorticoid receptors in the nucleus of the solitary tract (NTS) decrease endocrine and behavioral stress responses.Psychoneuroendocrinology, , 45 ,142-53 More Information

Herman, J P; Sladek, C D; Hansen, C T; Gash, D M (1986. ) Characterization of a new rodent model of diabetes insipidus: the Roman high avoidance rat homozygous for diabetes insipidus. Neuroendocrinology, , 43 (3 ) ,340-7

Flak, Jonathan N; Myers, Brent; Solomon, Matia B; McKlveen, Jessica M; Krause, Eric G; Herman, James P (2014. ) Role of paraventricular nucleus-projecting norepinephrine/epinephrine neurons in acute and chronic stress.The European journal of neuroscience, , 39 (11 ) ,1903-11 More Information

Herman, J P; Thomas, G J; Laycock, J F; Gartside, I B; Gash, D M (1986. ) Behavioral variability within the Brattleboro and Long-Evans rat strains. Physiology & behavior, , 36 (4 ) ,713-21

Hemmerle, A M; Dickerson, J W; Herman, J P; Seroogy, K B (2014. ) Stress exacerbates experimental Parkinson's disease.Molecular psychiatry, , 19 (6 ) ,638-40 More Information

Krause, Eric G; de Kloet, Annette D; Scott, Karen A; Flak, Jonathan N; Jones, Kenneth; Smeltzer, Michael D; Ulrich-Lai, Yvonne M; Woods, Stephen C; Wilson, Steven P; Reagan, Lawrence P; Herman, James P; Sakai, Randall R (2011. ) Blood-Borne Angiotensin II Acts in the Brain to Influence Behavioral and Endocrine Responses to Psychogenic Stress.The Journal of neuroscience : the official journal of the Society for Neuroscience, , 31 (42 ) ,15009-15015 More Information

Myers, Brent; McKlveen, Jessica M; Herman, James P (2014. ) Glucocorticoid actions on synapses, circuits, and behavior: implications for the energetics of stress.Frontiers in neuroendocrinology, , 35 (2 ) ,180-96 More Information

Hemmerle, Ann M; Herman, James P; Seroogy, Kim B (2011. ) Stress, depression and Parkinson's disease.Experimental neurology, , More Information

Solomon, Matia B; Wulsin, Aynara C; Rice, Taylor; Wick, Dayna; Myers, Brent; McKlveen, Jessica; Flak, Jonathan N; Ulrich-Lai, Yvonne; Herman, James P (2014. ) The selective glucocorticoid receptor antagonist CORT 108297 decreases neuroendocrine stress responses and immobility in the forced swim test.Hormones and behavior, , 65 (4 ) ,363-71 More Information

Radley, Jason J; Kabbaj, Mohamed; Jacobson, Lauren; Heydendael, Willem; Yehuda, Rachel; Herman, James P (2011. ) Stress risk factors and stress-related pathology: neuroplasticity, epigenetics and endophenotypes.Stress (Amsterdam, Netherlands), , 14 (5 ) ,481-97 More Information

Ryan, Karen K; Mul, Joram D; Clemmensen, Christoffer; Egan, Ann E; Begg, Denovan P; Halcomb, Kristen; Seeley, Randy J; Herman, James P; Ulrich-Lai, Yvonne M (2014. ) Loss of melanocortin-4 receptor function attenuates HPA responses to psychological stress.Psychoneuroendocrinology, , 42 ,98-105 More Information

Herman, James P (2011. ) Composite reviews from the 2010 Neurobiology of Stress Workshop.Stress (Amsterdam, Netherlands), , 14 (5 ) ,465-7 More Information

Carhuatanta, Kimberly A K; Shea, Chloe J A; Herman, James P; Jankord, Ryan (2014. ) Unique genetic loci identified for emotional behavior in control and chronic stress conditions.Frontiers in behavioral neuroscience, , 8 ,341 More Information

de Kloet, Annette D; Krause, Eric G; Scott, Karen A; Foster, Michelle T; Herman, James P; Sakai, Randall R; Seeley, Randy J; Woods, Stephen C (2011. ) Central angiotensin-II has catabolic action at white and brown adipose tissue.American journal of physiology. Endocrinology and metabolism, , More Information

McKlveen, Jessica M; Myers, Brent; Flak, Jonathan N; Bundzikova, Jana; Solomon, Matia B; Seroogy, Kim B; Herman, James P (2013. ) Role of prefrontal cortex glucocorticoid receptors in stress and emotion.Biological psychiatry, , 74 (9 ) ,672-9 More Information

Jones, Kenneth R; Myers, Brent; Herman, James P (2011. ) Stimulation of the prelimbic cortex differentially modulates neuroendocrine responses to psychogenic and systemic stressors.Physiology & behavior, , 104 (2 ) ,266-71 More Information

Kopp, Brittany L; Wick, Dayna; Herman, James P (2013. ) Differential effects of homotypic vs. heterotypic chronic stress regimens on microglial activation in the prefrontal cortex.Physiology & behavior, , 122 ,246-52 More Information

Flak, Jonathan N; Jankord, Ryan; Solomon, Matia B; Krause, Eric G; Herman, James P (2011. ) Opposing effects of chronic stress and weight restriction on cardiovascular, neuroendocrine and metabolic function.Physiology & behavior, , 104 (2 ) ,228-34 More Information

Ghosal, Sriparna; Myers, Brent; Herman, James P (2013. ) Role of central glucagon-like peptide-1 in stress regulation.Physiology & behavior, , 122 ,201-7 More Information

Carvalho-Netto, Eduardo F; Myers, Brent; Jones, Kenneth; Solomon, Matia B; Herman, James P (2011. ) Sex differences in synaptic plasticity in stress-responsive brain regions following chronic variable stress.Physiology & behavior, , 104 (2 ) ,242-7 More Information

Vincent, Melanie Y; Hussain, Rifat J; Zampi, Michael E; Sheeran, Katherine; Solomon, Matia B; Herman, James P; Khan, Anum; Jacobson, Lauren (2013. ) Sensitivity of depression-like behavior to glucocorticoids and antidepressants is independent of forebrain glucocorticoid receptors.Brain research, , 1525 ,1-15 More Information

Tasker, Jeffrey G; Herman, James P (2011. ) Mechanisms of rapid glucocorticoid feedback inhibition of the hypothalamic-pituitary-adrenal axis.Stress (Amsterdam, Netherlands), , 14 (4 ) ,398-406 More Information

de Kloet, Annette D; Pati, Dipanwita; Wang, Lei; Hiller, Helmut; Sumners, Colin; Frazier, Charles J; Seeley, Randy J; Herman, James P; Woods, Stephen C; Krause, Eric G (2013. ) Angiotensin type 1a receptors in the paraventricular nucleus of the hypothalamus protect against diet-induced obesity.The Journal of neuroscience : the official journal of the Society for Neuroscience, , 33 (11 ) ,4825-33 More Information

Ulrich-Lai, Yvonne M; Jones, Kenneth R; Ziegler, Dana R; Cullinan, William E; Herman, James P (2011. ) Forebrain origins of glutamatergic innervation to the rat paraventricular nucleus of the hypothalamus: differential inputs to the anterior versus posterior subregions.The Journal of comparative neurology, , 519 (7 ) ,1301-19 More Information

Crestani, Carlos C; Alves, Fernando Hf; Gomes, Felipe V; Resstel, Leonardo Bm; Correa, Fernando Ma; Herman, James P (2013. ) Mechanisms in the bed nucleus of the stria terminalis involved in control of autonomic and neuroendocrine functions: a review.Current neuropharmacology, , 11 (2 ) ,141-59 More Information

Christiansen, A M; Dekloet, A D; Ulrich-Lai, Y M; Herman, J P (2011. ) "Snacking" causes long term attenuation of HPA axis stress responses and enhancement of brain FosB/deltaFosB expression in rats.Physiology & behavior, , 103 (1 ) ,111-6 More Information

Herman, James P (2013. ) Neural control of chronic stress adaptation.Frontiers in behavioral neuroscience, , 7 ,61 More Information

Ulrich-Lai, Yvonne M; Ostrander, Michelle M; Herman, James P (2011. ) HPA axis dampening by limited sucrose intake: reward frequency vs. caloric consumption.Physiology & behavior, , 103 (1 ) ,104-10 More Information

Johnson, Erica M; Traver, Kyle L; Hoffman, Stuart W; Harrison, Catherine R; Herman, James P (2013. ) Environmental enrichment protects against functional deficits caused by traumatic brain injury.Frontiers in behavioral neuroscience, , 7 ,44 More Information

Krause, Eric G; de Kloet, Annette D; Flak, Jonathan N; Smeltzer, Michael D; Solomon, Matia B; Evanson, Nathan K; Woods, Stephen C; Sakai, Randall R; Herman, James P (2011. ) Hydration state controls stress responsiveness and social behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience, , 31 (14 ) ,5470-6 More Information

Herman, James P (2013. ) The future of stress: perspective of the new editor-in-chief.Stress (Amsterdam, Netherlands), , 16 (1 ) ,1-2 More Information

Castañeda, T R; Nogueiras, R; Müller, T D; Krishna, R; Grant, E; Jones, A; Ottaway, N; Ananthakrishnan, G; Pfluger, P T; Chaudhary, N; Solomon, M B; Woods, S C; Herman, J P; Tschöp, M H (2011. ) Decreased glucose tolerance and plasma adiponectin:resistin ratio in a mouse model of post-traumatic stress disorder.Diabetologia, , 54 (4 ) ,900-9 More Information

Flak, Jonathan N; Solomon, Matia B; Jankord, Ryan; Krause, Eric G; Herman, James P (2012. ) Identification of chronic stress-activated regions reveals a potential recruited circuit in rat brain.The European journal of neuroscience, , 36 (4 ) ,2547-55 More Information

Barrera, Jason G; Jones, Kenneth R; Herman, James P; D'Alessio, David A; Woods, Stephen C; Seeley, Randy J (2011. ) Hyperphagia and increased fat accumulation in two models of chronic CNS glucagon-like peptide-1 loss of function.The Journal of neuroscience : the official journal of the Society for Neuroscience, , 31 (10 ) ,3904-13 More Information

Herman, James P (2012. ) Neural pathways of stress integration: relevance to alcohol abuse. Alcohol research : current reviews, , 34 (4 ) ,441-7

Christiansen, A M; Herman, J P; Ulrich-Lai, Y M (2011. ) Regulatory interactions of stress and reward on rat forebrain opioidergic and GABAergic circuitry.Stress (Amsterdam, Netherlands), , 14 (2 ) ,205-15 More Information

Castro, Olagide W; Santos, Victor R; Pun, Raymund Y K; McKlveen, Jessica M; Batie, Matthew; Holland, Katherine D; Gardner, Margaret; Garcia-Cairasco, Norberto; Herman, James P; Danzer, Steve C (2012. ) Impact of corticosterone treatment on spontaneous seizure frequency and epileptiform activity in mice with chronic epilepsy.PloS one, , 7 (9 ) ,e46044 More Information

Jankord, Ryan; Solomon, Matia B; Albertz, Jennifer; Flak, Jonathan N; Zhang, Rong; Herman, James P (2011. ) Stress vulnerability during adolescent development in rats.Endocrinology, , 152 (2 ) ,629-38 More Information

Doczy E.;Seroogy K.;Harrison C.;Herman J. (05-01-2009. ) Hypothalamo-Pituitary-Adrenocortical Axis, Glucocorticoids, and Neurologic Disease.Immunology and Allergy Clinics of North America, , 29 (2 ) ,265-284 More Information

Solomon, Matia B; Jankord, Ryan; Flak, Jonathan N; Herman, James P (2011. ) Chronic stress, energy balance and adiposity in female rats.Physiology & behavior, , 102 (1 ) ,84-90 More Information

Zhang R.;Packard B.;Tauchi M.;D'Alessio D.;Herman J. (08-11-2009. ) Glucocorticoid regulation of preproglucagon transcription and RNA stability during stress (Proceedin.Proceedings of the National Academy of Sciences of the United States of America, , 106 (32 ) ,13636 More Information

McGuire, Jennifer L; Larke, Lauren E; Sallee, Floyd R; Herman, James P; Sah, Renu (2011. ) Differential Regulation of Neuropeptide Y in the Amygdala and Prefrontal Cortex during Recovery from Chronic Variable Stress.Frontiers in behavioral neuroscience, , 5 ,54 More Information

Benoit S.;Kemp C.;Elias C.;Abplanalp W.;Herman J.;Migrenne S.;Lefevre A.;Cruciani-Guglielmacci C.;Magnan C.;Yu F.;Niswender K.;Irani B.;Holland W.;Clegg D. (01-04-2010. ) Palmitic acid mediates hypothalamic insulin resistance by altering PKC-q subcellular localization in.Journal of Clinical Investigation, , 120 (1 ) ,394 More Information

Ulrich-Lai, Yvonne M; Christiansen, Anne M; Ostrander, Michelle M; Jones, Amanda A; Jones, Kenneth R; Choi, Dennis C; Krause, Eric G; Evanson, Nathan K; Furay, Amy R; Davis, Jon F; Solomon, Matia B; de Kloet, Annette D; Tamashiro, Kellie L; Sakai, Randall R; Seeley, Randy J; Woods, Stephen C; Herman, James P (2010. ) Pleasurable behaviors reduce stress via brain reward pathways.Proceedings of the National Academy of Sciences of the United States of America, , 107 (47 ) ,20529-34 More Information

Benoit S.C.;Kemp C.J.;Elias C.F.;Abplanalp W.;Herman J.P.;Migrenne S.;Lefevre A.L.;Cruciani-Guglielmacci C.;Magnan C.;Yu F.;Niswender K.;Irani B.G.;Holland W.L.;Clegg D.J. (01-04-2011. ) Palmitic acid mediates hypothalamic insulin resistance by altering PKC-? subcellular localization in .Journal of Clinical Investigation, , 121 (1 ) ,456

Zhang, Rong; Jankord, Ryan; Flak, Jonathan N; Solomon, Matia B; D'Alessio, David A; Herman, James P (2010. ) Role of glucocorticoids in tuning hindbrain stress integration.The Journal of neuroscience : the official journal of the Society for Neuroscience, , 30 (44 ) ,14907-14 More Information

McGuire J.;Larke L.;Sallee F.;Herman J.;Sah R. (09-01-2011. ) Differential regulation of neuropeptide Y in the amygdala and prefrontal cortex during recovery from.Frontiers in Behavioral Neuroscience, , (SEPTEMBER ) , More Information

Ziegler, Dana R; Herman, James P (2002. ) Neurocircuitry of stress integration: anatomical pathways regulating the hypothalamo-pituitary-adrenocortical axis of the rat.Integrative and comparative biology, , 42 (3 ) ,541-51 More Information

Myers B.;McKlveen J.;Herman J. (07-01-2012. ) Neural regulation of the stress response: The many faces of feedback.Cellular and Molecular Neurobiology, , 32 (5 ) ,683-694 More Information

Yi C.;Gericke M.;Krüger M.;Alkemade A.;Kabra D.;Hanske S.;Filosa J.;Pfluger P.;Bingham N.;Woods S.;Herman J.;Kalsbeek A.;Baumann M.;Lang R.;Stern J.;Bechmann I.;Tschöp M. (12-01-2012. ) High calorie diet triggers hypothalamic angiopathy.Molecular Metabolism, , 1 (1-2 ) ,95-100 More Information

Crestani C.;Alves F.;Gomes F.;Resstel L.;Correa F.;Herman J. (04-30-2013. ) Mechanisms in the bed nucleus of the stria terminalis involved in control of autonomic and neuroendo.Current Neuropharmacology, , 11 (2 ) ,141-159 More Information

Johnson E.;Traver K.;Hoffman S.;Harrison C.;Herman J. (05-08-2013. ) Environmental enrichment protects against functional deficits caused by traumatic brain injury.Frontiers in Behavioral Neuroscience, , (APR 2013 ) , More Information

Herman J. (05-21-2013. ) Neural control of chronic stress adaptation.Frontiers in Behavioral Neuroscience, , (MAY ) , More Information

Herman J.P. (12-01-2010. ) Stress Response: Neural and Feedback Regulation of the HPA Axis.Encyclopedia of Neuroscience, , 505-510 More Information

Solomon M.B.;Herman J.P. (12-01-2010. ) Sex differences in hpa-axis regulation: The role of gonadal hormones.Hormones, Brain and Behavior Online, , 2291-2308 More Information

Herman J. (10-14-2011. ) Central Nervous System Regulation of the Hypothalamic-Pituitary-Adrenal Axis Stress Response.The Handbook of Stress: Neuropsychological Effects on the Brain, , 29-46 More Information

Carhuatanta K.;Shea C.;Herman J.;Jankord R. (10-21-2014. ) Unique genetic loci identified for emotional behavior in control and chronic stress conditions.Frontiers in Behavioral Neuroscience, , 8 (OCT ) , More Information

Woods S.;Herman J. (01-01-2015. ) Brain insulin receptors link stress and metabolism.Molecular Metabolism, , 4 (2 ) ,77-78 More Information

de Kloet A.D.;Krause E.G.;Solomon M.B.;Flak J.N.;Scott K.A.;Kim D.H.;Myers B.;Ulrich-Lai Y.M.;Woods S.C.;Seeley R.J.;Herman J.P. (01-01-2015. ) Adipocyte glucocorticoid receptors mediate fat-to-brain signaling.Psychoneuroendocrinology, , 56 ,110-119 More Information

McKlveen J.;Myers B.;Herman J. (01-01-2015. ) The Medial Prefrontal Cortex: Coordinator of Autonomic, Neuroendocrine and Behavioural Responses to .Journal of Neuroendocrinology, , 27 (6 ) ,446-456 More Information

Makinson R.;Lundgren K.;Seroogy K.;Herman J. (07-01-2015. ) Chronic social subordination stress modulates glutamic acid decarboxylase (GAD) 67 mRNA expression i.Physiology and Behavior, , 146 ,7-15 More Information

Evanson N.;Herman J. (10-05-2015. ) Metabotropic glutamate receptor-mediated signaling dampens the HPA axis response to restraint stress.Physiology and Behavior, , 150 ,2-7 More Information

Ulrich-Lai Y.;Christiansen A.;Wang X.;Song S.;Herman J. (07-01-2016. ) Statistical modeling implicates neuroanatomical circuit mediating stress relief by ‘comfort’ food.Brain Structure and Function, , 221 (6 ) ,3141-3156 More Information

Bundzikova-Osacka J.;Ghosal S.;Packard B.;Ulrich-Lai Y.;Herman J. (01-01-2015. ) Role of nucleus of the solitary tract noradrenergic neurons in post-stress cardiovascular and hormon.Stress, , 18 (2 ) ,221-232 More Information

Ghosal S.;Nunley A.;Mahbod P.;Lewis A.G.;Smith E.P.;Tong J.;D'Alessio D.A.;Herman J.P. (10-05-2015. ) Mouse handling limits the impact of stress on metabolic endpoints.Physiology and Behavior, , 150 ,31-37 More Information

Herman J.;Maroun M.;Richter-Levin G. (01-01-2015. ) Good stress, bad stress and very bad stress.Stress, , 18 (3 ) ,267-268 More Information

Myers B.;Carvalho-Netto E.;Wick-Carlson D.;Wu C.;Naser S.;Solomon M.;Ulrich-Lai Y.;Herman J. (05-01-2016. ) GABAergic signaling within a limbic-hypothalamic circuit integrates social and anxiety-like behavior.Neuropsychopharmacology, , 41 (6 ) ,1530-1539 More Information

Wulsin A.;Wick-Carlson D.;Packard B.;Morano R.;Herman J. (03-01-2016. ) Adolescent chronic stress causes hypothalamo-pituitary-adrenocortical hypo-responsiveness and depres.Psychoneuroendocrinology, , 65 ,109-117 More Information

Goodson M.;Packard A.;Buesing D.;Maney M.;Myers B.;Fang Y.;Basford J.;Hui D.;Ulrich-Lai Y.;Herman J.;Ryan K. (01-11-2016. ) Chronic stress and Rosiglitazone increase indices of vascular stiffness in male rats.Physiology and Behavior, , More Information

Smith B.;Schmeltzer S.;Packard B.;Sah R.;Herman J. (10-01-2016. ) Divergent effects of repeated restraint versus chronic variable stress on prefrontal cortical immune.Brain, Behavior, and Immunity, , 57 ,263-270 More Information

McKlveen J.;Morano R.;Fitzgerald M.;Zoubovsky S.;Cassella S.;Scheimann J.;Ghosal S.;Mahbod P.;Packard B.;Myers B.;Baccei M.;Herman J. (09-29-2015. ) Chronic Stress Increases Prefrontal Inhibition: A Mechanism for Stress-Induced Prefrontal Dysfunctio.Biological Psychiatry, , More Information

Wulsin A.;Solomon M.;Privitera M.;Danzer S.;Herman J. (11-01-2016. ) Hypothalamic-pituitary-adrenocortical axis dysfunction in epilepsy.Physiology and Behavior, , 166 ,22-31 More Information

Myers B.;Scheimann J.;Franco-Villanueva A.;Herman J. (02-20-2016. ) Ascending mechanisms of stress integration: Implications for brainstem regulation of neuroendocrine .Neuroscience and Biobehavioral Reviews, , More Information

Franco A.;Chen C.;Scullen T.;Zsombok A.;Salahudeen A.;Di S.;Herman J.;Tasker J. (06-01-2016. ) Sensitization of the hypothalamic-pituitary-adrenal axis in a male rat chronic stress model.Endocrinology, , 157 (6 ) ,2346-2355 More Information

Jezova D.;Herman J. (07-03-2016. ) Lessons from regular gathering of experts in stress research: focus on pathophysiological consequenc.Stress, , 19 (4 ) ,339-340 More Information

Schmeltzer S.;Herman J.;Sah R. (10-01-2016. ) Neuropeptide Y (NPY) and posttraumatic stress disorder (PTSD): A translational update.Experimental Neurology, , 284 ,196-210 More Information

Prewitt C.M.F.;Herman J.P. (01-01-1997. ) Hypothalamo-pituitary-adrenocortical regulation following lesions of the central nucleus of the amyg .Stress, , 1 (4 ) ,263-279

Herman J.;Chen K.;Booze R.;Landfield P. (12-01-1998. ) Up-regulation of ?(1D) Ca 2+ channel subunit mRNA expression in the hippocampus o.Neurobiology of Aging, , 19 (6 ) ,581-587 More Information

Herman J. (03-11-1999. ) Neurocircuit control of the hypothalamo-pituitary-adrenocortical axis during stress.Current Opinion in Endocrinology and Diabetes, , 6 (1 ) ,3-9 More Information

Ziegler D.R.;Herman J.P. (06-01-2002. ) Neurocircuitry of stress integration: Anatomical pathways regulating the hypothalamo-pituitary-adren .Integrative and Comparative Biology, , 42 (3 ) ,541-551

Herman J.;Mueller N.;Figueiredo H.;Cullinan W. (12-01-2005. ) Chapter 4.1 Neurocircuit regulation of the hypothalamo-pituitary-adrenocortical stress response - an.Techniques in the Behavioral and Neural Sciences, , 15 (PART 1 ) ,405-418 More Information

Wise P.M.;Herman J.P.;Landfield P.W. (12-01-1997. ) Chapter 8 Neuroendocrine Aspects of the Aging Brain.Advances in Cell Aging and Gerontology, , 2 (C ) ,193-241 More Information

Herman J.P.;Figueiredo H.F.;Mueller N.K.;Ostrander M.M.;Zhang R.;Tauchi M.;Choi D.C.;Furay A.R.;Evanson N.K.;Nelson E.B.;Ulrich-Lai Y.M. (12-01-2007. ) Neurochemical systems regulating the hypothalamo-pituitary-adrenocortical axis.Handbook of Neurochemistry and Molecular Neurobiology: Behavioral Neurochemistry, Neuroendocrinology and Molecular Neurobiology, , 513-569 More Information

Becker J.B.;Berkley K.J.;Geary N.;Hampson E.;Herman J.P.;Young E. (12-04-2007. ) Sex Differences in the Brain: From Genes to Behavior.Sex Differences in the Brain: From Genes to Behavior, , 1-512 More Information

Young E.A.;Korszun A.;Figueiredo H.F.;Banks-Solomon M.;Herman J.P. (12-04-2007. ) Sex Differences in HPA Axis Regulation.Sex Differences in the Brain: From Genes to Behavior, , More Information

Eckel L.A.;Arnold A.P.;Hampson E.;Becker J.B.;Blaustein J.D.;Herman J.P. (12-04-2007. ) Research and Methodological Issues in the Study of Sex Differences and Hormone-Behavior Relations.Sex Differences in the Brain: From Genes to Behavior, , More Information

Schafer M.K.H.;Herman J.P.;Watson S.J. (01-01-1990. ) Rapid detection of POMC heteronuclear RNA in individual pituitary cells by in situ hybridization .New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914, , 307

Herman J.P.;Watson S.J.;Chao H.M.;Coirini H.;McEwen B.S. (12-01-1993. ) Diurnal regulation of glucocorticoid receptor and mineralocorticoid receptor mRNAs in rat hippocampu .Molecular and Cellular Neuroscience, , 4 (2 ) ,181-190

Jessen, Lene; Smith, Eric P; Ulrich-Lai, Yvonne; Herman, James P; Seeley, Randy J; Sandoval, Darleen; D'Alessio, David (2017. ) Central Nervous System GLP-1 Receptors Regulate Islet Hormone Secretion and Glucose Homeostasis in Male Rats.Endocrinology, , More Information

Goodson, M L; Packard, A E B; Buesing, D R; Maney, M; Myers, B; Fang, Y; Basford, J E; Hui, D Y; Ulrich-Lai, Y M; Herman, J P; Ryan, K K (2017. ) Chronic stress and Rosiglitazone increase indices of vascular stiffness in male rats.Physiology & behavior, , 172 ,16-23 More Information

Myers, Brent; Scheimann, Jessie R; Franco-Villanueva, Ana; Herman, James P (2017. ) Ascending mechanisms of stress integration: Implications for brainstem regulation of neuroendocrine and behavioral stress responses.Neuroscience and biobehavioral reviews, , 74 (Pt B ) ,366-375 More Information

Smith, Brittany L; Lyons, Carey E; Correa, Fernanda Guilhaume; Benoit, Stephen C; Myers, Brent; Solomon, Matia B; Herman, James P (2017. ) Behavioral and physiological consequences of enrichment loss in rats.Psychoneuroendocrinology, , 77 ,37-46 More Information

Herman, James P; Tamashiro, Kellie L (2017. ) The visible burrow system: A view from across the hall.Physiology & behavior, , More Information

Ghosal, Sriparna; Packard, Amy E B; Mahbod, Parinaz; McKlveen, Jessica M; Seeley, Randy J; Myers, Brent; Ulrich-Lai, Yvonne; Smith, Eric P; D'Alessio, David A; Herman, James P (2017. ) Disruption of Glucagon-Like Peptide 1 Signaling in Sim1 Neurons Reduces Physiological and Behavioral Reactivity to Acute and Chronic Stress.The Journal of neuroscience : the official journal of the Society for Neuroscience, , 37 (1 ) ,184-193 More Information

Huff, Courtney L; Morano, Rachel L; Herman, James P; Yamamoto, Bryan K; Gudelsky, Gary A (2016. ) MDMA decreases glutamic acid decarboxylase (GAD) 67-immunoreactive neurons in the hippocampus and increases seizure susceptibility: Role for glutamate.Neurotoxicology, , 57 ,282-290 More Information

Wulsin, Aynara C; Herman, James P; Danzer, Steve C (2016. ) RU486 Mitigates Hippocampal Pathology Following Status Epilepticus.Frontiers in neurology, , 7 ,214 More Information

McKlveen, Jessica M; Morano, Rachel L; Fitzgerald, Maureen; Zoubovsky, Sandra; Cassella, Sarah N; Scheimann, Jessie R; Ghosal, Sriparna; Mahbod, Parinaz; Packard, Benjamin A; Myers, Brent; Baccei, Mark L; Herman, James P (2016. ) Chronic Stress Increases Prefrontal Inhibition: A Mechanism for Stress-Induced Prefrontal Dysfunction.Biological psychiatry, , 80 (10 ) ,754-764 More Information

Wulsin, Aynara C; Solomon, Matia B; Privitera, Michael D; Danzer, Steve C; Herman, James P (2016. ) Hypothalamic-pituitary-adrenocortical axis dysfunction in epilepsy.Physiology & behavior, , 166 ,22-31 More Information

Herman, James P; Tasker, Jeffrey G (2016. ) Paraventricular Hypothalamic Mechanisms of Chronic Stress Adaptation.Frontiers in endocrinology, , 7 ,137 More Information

Vollmer, Lauren Larke; Ghosal, Sriparna; McGuire, Jennifer L; Ahlbrand, Rebecca L; Li, Ke-Yong; Santin, Joseph M; Ratliff-Rang, Christine A; Patrone, Luis G A; Rush, Jennifer; Lewkowich, Ian P; Herman, James P; Putnam, Robert W; Sah, Renu (2016. ) Microglial Acid Sensing Regulates Carbon Dioxide-Evoked Fear.Biological psychiatry, , 80 (7 ) ,541-51 More Information

Smith, Brittany L; Schmeltzer, Sarah N; Packard, Benjamin A; Sah, Renu; Herman, James P (2016. ) Divergent effects of repeated restraint versus chronic variable stress on prefrontal cortical immune status after LPS injection.Brain, behavior, and immunity, , 57 ,263-70 More Information

Schmeltzer, Sarah N; Herman, James P; Sah, Renu (2016. ) Neuropeptide Y (NPY) and posttraumatic stress disorder (PTSD): A translational update.Experimental neurology, , 284 (Pt B ) ,196-210 More Information

Ulrich-Lai, Yvonne M; Christiansen, Anne M; Wang, Xia; Song, Seongho; Herman, James P (2016. ) Statistical modeling implicates neuroanatomical circuit mediating stress relief by 'comfort' food.Brain structure & function, , 221 (6 ) ,3141-56 More Information

Jezova, Daniela; Herman, James P (2016. ) Lessons from regular gathering of experts in stress research: focus on pathophysiological consequences of stress exposure.Stress (Amsterdam, Netherlands), , 19 (4 ) ,339-40 More Information

Franco, Alier J; Chen, Chun; Scullen, Tyler; Zsombok, Andrea; Salahudeen, Ahmed A; Di, Shi; Herman, James P; Tasker, Jeffrey G (2016. ) Sensitization of the Hypothalamic-Pituitary-Adrenal Axis in a Male Rat Chronic Stress Model.Endocrinology, , 157 (6 ) ,2346-55 More Information

Myers, Brent; Carvalho-Netto, Eduardo; Wick-Carlson, Dayna; Wu, Christine; Naser, Sam; Solomon, Matia B; Ulrich-Lai, Yvonne M; Herman, James P (2016. ) GABAergic Signaling within a Limbic-Hypothalamic Circuit Integrates Social and Anxiety-Like Behavior with Stress Reactivity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, , 41 (6 ) ,1530-9 More Information

Herman, James P; McKlveen, Jessica M; Ghosal, Sriparna; Kopp, Brittany; Wulsin, Aynara; Makinson, Ryan; Scheimann, Jessie; Myers, Brent (2016. ) Regulation of the Hypothalamic-Pituitary-Adrenocortical Stress Response.Comprehensive Physiology, , 6 (2 ) ,603-21 More Information

Wulsin, Aynara C; Wick-Carlson, Dayna; Packard, Benjamin A; Morano, Rachel; Herman, James P (2016. ) Adolescent chronic stress causes hypothalamo-pituitary-adrenocortical hypo-responsiveness and depression-like behavior in adult female rats.Psychoneuroendocrinology, , 65 ,109-17 More Information

Evanson, Nathan K; Herman, James P Role of Paraventricular Nucleus Glutamate Signaling in Regulation of HPA Axis Stress Responses.Interdisciplinary information sciences, , 21 (3 ) ,253-260 More Information

Busnardo, Cristiane; Crestani, Carlos C; Scopinho, América A; Packard, Benjamin A; Resstel, Leonardo B M; Correa, Fernando M A; Herman, James P (2019. ) Nitrergic neurotransmission in the paraventricular nucleus of the hypothalamus modulates autonomic, neuroendocrine and behavioral responses to acute restraint stress in rats.Progress in neuro-psychopharmacology & biological psychiatry, , 90 ,16-27 More Information

Cotella, Evelin M; Gómez, Antonela Scarponi; Lemen, Paige; Chen, Carrie; Fernández, Guillermo; Hansen, Christian; Herman, James P; Paglini, María Gabriela (2019. ) Long-term impact of chronic variable stress in adolescence versus adulthood.Progress in neuro-psychopharmacology & biological psychiatry, , 88 ,303-310 More Information

Scheimann, Jessie R; Mahbod, Parinaz; Morano, Rachel; Frantz, Lindsey; Packard, Ben; Campbell, Kenneth; Herman, James P (2018. ) Deletion of Glucocorticoid Receptors in Forebrain GABAergic Neurons Alters Acute Stress Responding and Passive Avoidance Behavior in Female Mice.Frontiers in behavioral neuroscience, , 12 ,325 More Information

Wood, Miranda; Adil, Othman; Wallace, Tyler; Fourman, Sarah; Wilson, Steven P; Herman, James P; Myers, Brent (2018. ) Infralimbic prefrontal cortex structural and functional connectivity with the limbic forebrain: a combined viral genetic and optogenetic analysis.Brain structure & function, , More Information

Smith, Brittany L; Morano, Rachel L; Ulrich-Lai, Yvonne M; Myers, Brent; Solomon, Matia B; Herman, James P (2018. ) Adolescent environmental enrichment prevents behavioral and physiological sequelae of adolescent chronic stress in female (but not male) rats.Stress (Amsterdam, Netherlands), , 21 (5 ) ,464-473 More Information

Wulsin, Aynara C; Franco-Villanueva, Ana; Romancheck, Christian; Morano, Rachel L; Smith, Brittany L; Packard, Benjamin A; Danzer, Steve C; Herman, James P (2018. ) Functional disruption of stress modulatory circuits in a model of temporal lobe epilepsy.PloS one, , 13 (5 ) ,e0197955 More Information

Evanson, Nathan K; Guilhaume-Correa, Fernanda; Herman, James P; Goodman, Michael D (2018. ) Optic tract injury after closed head traumatic brain injury in mice: A model of indirect traumatic optic neuropathy.PloS one, , 13 (5 ) ,e0197346 More Information

Herman, James P (2018. ) Regulation of Hypothalamo-Pituitary-Adrenocortical Responses to Stressors by the Nucleus of the Solitary Tract/Dorsal Vagal Complex.Cellular and molecular neurobiology, , 38 (1 ) ,25-35 More Information

Mahbod, Parinaz; Smith, Eric P; Fitzgerald, Maureen E; Morano, Rachel L; Packard, Benjamin A; Ghosal, Sriparna; Scheimann, Jessie R; Perez-Tilve, Diego; Herman, James P; Tong, Jenny (2018. ) Desacyl Ghrelin Decreases Anxiety-like Behavior in Male Mice.Endocrinology, , 159 (1 ) ,388-399 More Information

de Kloet, Annette D; Herman, James P (2018. ) Fat-brain connections: Adipocyte glucocorticoid control of stress and metabolism.Frontiers in neuroendocrinology, , 48 ,50-57 More Information

Rainville, Jennifer R; Weiss, Grant L; Evanson, Nathan; Herman, James P; Vasudevan, Nandini; Tasker, Jeffrey G (2017. ) Membrane-initiated nuclear trafficking of the glucocorticoid receptor in hypothalamic neurons.Steroids, , More Information

Myers, Brent; McKlveen, Jessica M; Morano, Rachel; Ulrich-Lai, Yvonne M; Solomon, Matia B; Wilson, Steven P; Herman, James P (2017. ) Vesicular Glutamate Transporter 1 Knockdown in Infralimbic Prefrontal Cortex Augments Neuroendocrine Responses to Chronic Stress in Male Rats.Endocrinology, , 158 (10 ) ,3579-3591 More Information

Herman, James P (2017. ) New perspectives in stress research: 2016 neurobiology of stress workshop.Stress (Amsterdam, Netherlands), , 20 (5 ) ,419-420 More Information

Smail, Marissa A; Smith, Brittany L; Nawreen, Nawshaba; Herman, James P (2020. ) Differential impact of stress and environmental enrichment on corticolimbic circuits.Pharmacology, biochemistry, and behavior, , 197 ,172993 More Information

Rainville, Jennifer R; Weiss, Grant L; Evanson, Nathan; Herman, James P; Vasudevan, Nandini; Tasker, Jeffrey G (2020. ) Corrigendum to "Membrane-initiated nuclear trafficking of the glucocorticoid receptor in hypothalamic neurons" [Steroids 142 (2019) 55-64].Steroids, , 155 ,108382 More Information

Cotella, Evelin M; Morano, Rachel L; Wulsin, Aynara C; Martelle, Susan M; Lemen, Paige; Fitzgerald, Maureen; Packard, Benjamin A; Moloney, Rachel D; Herman, James P (2020. ) Lasting Impact of Chronic Adolescent Stress and Glucocorticoid Receptor Selective Modulation in Male and Female Rats.Psychoneuroendocrinology, , 112 ,104490 More Information

Schaeuble, Derek; Packard, Amy E B; McKlveen, Jessica M; Morano, Rachel; Fourman, Sarah; Smith, Brittany L; Scheimann, Jessie R; Packard, Benjamin A; Wilson, Steven P; James, Jeanne; Hui, David Y; Ulrich-Lai, Yvonne M; Herman, James P; Myers, Brent (2019. ) Prefrontal Cortex Regulates Chronic Stress-Induced Cardiovascular Susceptibility.Journal of the American Heart Association, , 8 (24 ) ,e014451 More Information

McKlveen, Jessica M; Moloney, Rachel D; Scheimann, Jessie R; Myers, Brent; Herman, James P (2019. ) "Braking" the Prefrontal Cortex: The Role of Glucocorticoids and Interneurons in Stress Adaptation and Pathology.Biological psychiatry, , 86 (9 ) ,669-681 More Information

Scheimann, Jessie R; Moloney, Rachel D; Mahbod, Parinaz; Morano, Rachel L; Fitzgerald, Maureen; Hoskins, Olivia; Packard, Benjamin A; Cotella, Evelin M; Hu, Yueh-Chiang; Herman, James P (2019. ) Conditional deletion of glucocorticoid receptors in rat brain results in sex-specific deficits in fear and coping behaviors.eLife, , 8 , More Information

Rincón-Cortés, Millie; Herman, James P; Lupien, Sonia; Maguire, Jamie; Shansky, Rebecca M (2019. ) Stress: Influence of sex, reproductive status and gender.Neurobiology of stress, , 10 ,100155 More Information

Morano, Rachel; Hoskins, Olivia; Smith, Brittany L; Herman, James P (2018. ) Loss of Environmental Enrichment Elicits Behavioral and Physiological Dysregulation in Female Rats.Frontiers in behavioral neuroscience, , 12 ,287 More Information

Pace, Sebastian A; Christensen, Connor; Schackmuth, Morgan K; Wallace, Tyler; McKlveen, Jessica M; Beischel, Will; Morano, Rachel; Scheimann, Jessie R; Wilson, Steven P; Herman, James P; Myers, Brent (2020. ) Infralimbic cortical glutamate output is necessary for the neural and behavioral consequences of chronic stress.Neurobiology of stress, , 13 ,100274 More Information

Herman, James P; Nawreen, Nawshaba; Smail, Marissa A; Cotella, Evelin M (2020. ) Brain mechanisms of HPA axis regulation: neurocircuitry and feedback in context Richard Kvetnansky lecture.Stress (Amsterdam, Netherlands), , 23 (6 ) ,617-632 More Information

Jezova, Daniela; Herman, James P (2020. ) Stress and stress-related disease states as topics of multi-approach research.Stress (Amsterdam, Netherlands), , 23 (6 ) ,615-616 More Information

Nawreen, Nawshaba; Cotella, Evelin M; Morano, Rachel; Mahbod, Parinaz; Dalal, Khushali S; Fitzgerald, Maureen; Martelle, Susan; Packard, Benjamin A; Franco-Villanueva, Ana; Moloney, Rachel D; Herman, James P Chemogenetic Inhibition of Infralimbic Prefrontal Cortex GABAergic Parvalbumin Interneurons Attenuates the Impact of Chronic Stress in Male Mice.eNeuro, , 7 (5 ) , More Information

Smail, Marissa A; Wu, Xiaojun; Henkel, Nicholas D; Eby, Hunter M; Herman, James P; McCullumsmith, Robert E; Shukla, Rammohan (2021. ) Similarities and dissimilarities between psychiatric cluster disorders.Molecular psychiatry, , More Information

Smail, Marissa A; Wu, Xiaojun; Henkel, Nicholas D; Eby, Hunter M; Herman, James P; McCullumsmith, Robert E; Shukla, Rammohan (2021. ) Similarities and dissimilarities between psychiatric cluster disorders.Molecular psychiatry, , More Information

Wulsin, Aynara C; Kraus, Kimberly L; Gaitonde, Kevin D; Suru, Venkat; Arafa, Salwa R; Packard, Benjamin A; Herman, James P; Danzer, Steve C (2021. ) The glucocorticoid receptor specific modulator CORT108297 reduces brain pathology following status epilepticus.Experimental neurology, , 341 ,113703 More Information

Martelle, Susan E; Cotella, Evelin M; Nawreen, Nawshaba; Chen, Carrie; Packard, Benjamin A; Fitzgerald, Maureen; Herman, James P (2021. ) Prefrontal cortex PACAP signaling: organization and role in stress regulation.Stress (Amsterdam, Netherlands), , 24 (2 ) ,196-205 More Information

Kraus, Kimberly L; Nawreen, Nawshaba; Godale, Christin M; Chordia, Arihant P; Packard, Ben; LaSarge, Candi L; Herman, James P; Danzer, Steve C (2023. ) Hippocampal glucocorticoid receptors modulate status epilepticus severity.Neurobiology of disease, , 178 ,106014 More Information

Radley, Jason J; Herman, James P (2022. ) Preclinical Models of Chronic Stress: Adaptation or Pathology?.Biological psychiatry, , More Information

Smail, Marissa A; Chandrasena, Sapuni S; Zhang, Xiaolu; Reddy, Vineet; Kelley, Craig; Herman, James P; Sherif, Mohamed; McCullumsmith, Robert E; Shukla, Rammohan (2022. ) Differential vulnerability of anterior cingulate cortex cell types to diseases and drugs.Molecular psychiatry, , 27 (10 ) ,4023-4034 More Information

Kraus, Kimberly L; Chordia, Arihant P; Drake, Austin W; Herman, James P; Danzer, Steve C (2022. ) Hippocampal interneurons are direct targets for circulating glucocorticoids.The Journal of comparative neurology, , 530 (12 ) ,2100-2112 More Information

Herman, James P (2022. ) The neuroendocrinology of stress: Glucocorticoid signaling mechanisms.Psychoneuroendocrinology, , 137 ,105641 More Information

Nawreen, Nawshaba; Baccei, Mark L; Herman, James P (2021. ) Single Prolonged Stress Reduces Intrinsic Excitability and Excitatory Synaptic Drive Onto Pyramidal Neurons in the Infralimbic Prefrontal Cortex of Adult Male Rats.Frontiers in cellular neuroscience, , 15 ,705660 More Information

Kraus, Kimberly L; Nawreen, Nawshaba; Godale, Christin M; Chordia, Arihant P; Packard, Ben; LaSarge, Candi L; Herman, James P; Danzer, Steve C (2023. ) Hippocampal glucocorticoid receptors modulate status epilepticus severity.Neurobiology of disease, , 178 ,106014 More Information

Radley, Jason J; Herman, James P (2022. ) Preclinical Models of Chronic Stress: Adaptation or Pathology?.Biological psychiatry, , More Information

Smail, Marissa A; Chandrasena, Sapuni S; Zhang, Xiaolu; Reddy, Vineet; Kelley, Craig; Herman, James P; Sherif, Mohamed; McCullumsmith, Robert E; Shukla, Rammohan (2022. ) Differential vulnerability of anterior cingulate cortex cell types to diseases and drugs.Molecular psychiatry, , 27 (10 ) ,4023-4034 More Information

Kraus, Kimberly L; Chordia, Arihant P; Drake, Austin W; Herman, James P; Danzer, Steve C (2022. ) Hippocampal interneurons are direct targets for circulating glucocorticoids.The Journal of comparative neurology, , 530 (12 ) ,2100-2112 More Information

Herman, James P (2022. ) The neuroendocrinology of stress: Glucocorticoid signaling mechanisms.Psychoneuroendocrinology, , 137 ,105641 More Information

Nawreen, Nawshaba; Baccei, Mark L; Herman, James P (2021. ) Single Prolonged Stress Reduces Intrinsic Excitability and Excitatory Synaptic Drive Onto Pyramidal Neurons in the Infralimbic Prefrontal Cortex of Adult Male Rats.Frontiers in cellular neuroscience, , 15 ,705660 More Information

Smail, Marissa A; Smith, Brittany L; Shukla, Rammohan; Alganem, Khaled; Eby, Hunter M; Bollinger, Justin L; Parikh, Ria K; Chambers, James B; Reigle, James K; Moloney, Rachel D; Nawreen, Nawshaba; Wohleb, Eric S; Pantazopoulos, Harry; McCullumsmith, Robert E; Herman, James P (2023. ) Molecular neurobiology of loss: a role for basolateral amygdala extracellular matrix.Molecular psychiatry, , More Information

Cotella, Evelin M; Nawreen, Nawshaba; Moloney, Rachel D; Martelle, Susan E; Oshima, Kristen M; Lemen, Paige; NiBlack, Jordan N; Julakanti, Reetu R; Fitzgerald, Maureen; Baccei, Mark L; Herman, James P (2023. ) Adolescent Stress Confers Resilience to Traumatic Stress Later in Life: Role of the Prefrontal Cortex.Biological psychiatry global open science, , 3 (2 ) ,274-282 More Information

Published Books

J.B.Becker, K. Berkley, J.P. Herman, E. Hampson, E. Young and N.Geary (2007. ) Sex Differences in the Brain: From Genes to Behavior .Oxford University Press (Co-Editor)

1999 James and Barbara Holsinger endowed Chair in Anatomy and Neurobiology University of Kentucky

1997 College of Medicine Research Award University of Kentucky

1987 Thurnau Fellow, Center for Molecular Genetics University of Michigan

1986 Wallace O. Fenn Prize for Outstanding Ph.D. Thesis University of Rochester

2014 Donald C. Harrison Chair, University of Cincinnati

2016 Distinguished Research Professor (STEMM), University of Cincinnati

Stress Editor of Journal Type:Editorial Service Level:International 07-01-2012 -To Present

European Journal of Neuroscience Associate Editor Type:Editorial Service Level:International 01-01-2009 -To Present

Experimental Neurology Associate Editor Type:Editorial Service Level:International 01-01-2009 -12-31-2012

Relevant Links
Neuroscience Graduate Program ,

Stress Neurobiology Web Site,

Academic - College of Medicine
231 Albert Sabin Way
Cincinnati  Ohio, 45267-0576
Phone: 513-558-5636
Fax: 513-558-5738

Research - Stetson Building
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Cincinnati  Ohio, 45219
Phone: 513-558-7700
james.herman@uc.edu