Robert Duncan Hite , MD

BS: Southern Methodist University University Park, TX, 1982 (Chemistry)

MD: University of Texas Medical School Houston, TX, 1986

Residency: University of Virginia Medical Center Charlottesville, VA, 1989 (Internal Medicine)

Fellowship: University of California, San Diego Medical Center San Diego, CA, 1992 (Pulmonary and Critical Care Medicine)

American Board of Internal Medicine (Critical Care Medicine) (Certification Date: 11-03-1993 ) - (Recertification Date: to 09-14-2015 )

American Board of Internal Medicine (Certification Date: 09-13-1989 )

American Board of Internal Medicine (Pulmonary Disease) (Certification Date: 11-04-1992 ) - (Recertification Date: to 10-20-2015 )

Critical Care Medicine

Lung Disease

Pulmonary Disease

Carbon Monoxide Poisoning

Chronic Cough

Dyspnea

Histoplasmosis

Legionnaires' Disease (Legionellosis)

Pleurisy

Pneumonia

Pulmonary Edema

Respiration Disorders

Respiratory Insufficiency

Respiratory Syncytial Virus (RSV)

Respiratory Tract Disease

Respiratory Tract Infections

Severe Acute Respiratory Syndrome (SARS)

Shortness of Breath

Sin Nombre Virus Infection (Hantavirus pulmonary syndrome)

Thoracic Disease

Tuberculosis

Whooping Cough (Pertussis)

Critical Care Medicine

Internal Medicine

Grant: #507-SUB PETAL / U01 HL123023 Investigators:Branson, Richard; Hite, Robert; Hudock, Kristin; Lindsell, Christopher; Norton, David 06-17-2014 -04-30-2021 National Heart, Lung and Blood Institute Clinical Center for the NHLBI Prevention and Early Treatment of Acute Lung Injury (PETAL Network) Clinical Trials Network Role:PI $177,894.00 Active Level:Federal

Grant: #OSU 60074290 / R56 HL142767 Investigators:Hite, Robert 09-01-2019 -08-31-2020 National Heart, Lung and Blood Institute Dissecting the molecular mechanisms of lung injury during mechanical ventilation Role:PI $30,286.00 Active Level:Federal

Grant: #Purchase Order US001-0000792601 Investigators:Branson, Richard; Goodman, Michael; Hite, Robert; McMullan, Jason; Pritts, Timothy 07-28-2020 -11-16-2021 Department of the Air Force US AIR FORCE RESEARCH LABORATORY COVID-19 BREATH ANALYSIS ACTIVITY Role:Collaborator $228,170.00 Awarded Level:Federal

Grant: #N/A Investigators:Hite, Robert 07-01-2020 -06-30-2021 UC's Launch Awards Spring Semester (20SS) Research Launch Awards Role:PI $3,500.00 Active Level:Internal UC

Grant: #12345 / NHLBI Investigators:Hite, Robert; Hudock, Kristin 04-20-2020 -04-19-2021 National Heart, Lung and Blood Institute ORCHID Role:PI $75,047.65 Active Level:Federal

Grant: #Fred Hutchinson Cancer Research Center 0001060630 / UG3HL147011 Investigators:Hite, Robert 09-16-2020 -08-31-2021 National Heart, Lung and Blood Institute Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients with Acute Respiratory Failure and Sepsis Role:PI $8,413.00 Awarded Level:Federal

Grant: #Cleveland Clinic / OT2HL156812 Investigators:Hite, Robert 09-01-2020 -08-31-2021 National Heart, Lung and Blood Institute ACTIV-3 Role:PI $231,200.00 Active Level:Federal

Grant: #OSU 60074290 / R01HL142767 Investigators:Hite, Robert 02-15-2021 -01-31-2026 Ohio State University Dissecting the molecular mechanisms of lung injury during mechanical ventilation Role:PI 0.00 Hold Level:Higher Education

Grant: #OSU 60074290 / R01HL142767 Investigators:Hite, Robert 02-15-2021 -01-31-2026 Ohio State University Dissecting the molecular mechanisms of lung injury during mechanical ventilation Role:PI 26430.57 Hold Level:Higher Education

Grant: #PETAL ACTIVE-3(TESICO)/OT2HL156812 Investigators:Hite, Robert 07-01-2021 -06-30-2022 Cleveland Clinic PETAL Network ICC for ACTIV-3 "Therapeutics for Severely Ill Inpatients with COVID-19 (TESICO) Role:PI 612300.00 Hold Level:Non Profit

Grant: #ASTER U01HL123009 Investigators:Hite, Robert; Hudock, Kristin 08-01-2021 -10-31-2022 Cleveland Clinic ASTER Role:Collaborator 117664.00 Hold Level:Non Profit

Grant: #TBA/ 4 UH3 HL147011-02 Investigators:Hite, Robert 04-01-2022 -08-31-2027 Fred Hutchinson Cancer Center Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients with Acute Respiratory Failure and Sepsis Role:PI 0.00 Hold Level:Non Profit

Grant: #CCHMC tba /U01HL123009-07S1 Investigators:Fermann, Gregory; Hite, Robert; Hudock, Kristin 10-01-2021 -10-31-2022 National Heart, Lung and Blood Institute PETAL Core Admin Role:PI 97221.00 Hold Level:Federal

Grant: #FCC 0001131418 CR/ 0001131422 FR/ 5 UH3 HL147011-04 Investigators:Hite, Robert 09-01-2022 -08-31-2027 National Heart, Lung and Blood Institute Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients with Acute Respiratory Failure and Sepsis Role:PI 47862.50 Hold Level:Federal

Grant: #CCF tba/5U01HL123009-07 Investigators:Fermann, Gregory; Hite, Robert; Hudock, Kristin 11-01-2022 -12-31-2023 National Heart, Lung and Blood Institute PETAL Core Admin Role:PI 44874.00 Hold Level:Federal

Grant: #VUMC 109518; 1OT2HL156812-01 Investigators:Hite, Robert; Hudock, Kristin -04-30-2023 National Heart, Lung and Blood Institute Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE): Trial 1 Shionogi Protease Inhibitor (S-217622) Role:PI 0.00 Hold Level:Federal

Peer Reviewed Publications

Baron, Rebecca M; Christman, John W; Liu, Kathleen D; Matthay, Michael A; Self, Wesley H; McVerry, Bryan J; Hite, R Duncan; Paine, Robert; Wurfel, Mark M; Shapiro, Nathan I; Adams, Peter W; Schmidt, Eric P; Ringwood, Nancy (2020. ) Monitoring Research Blood Sampling in Critically Ill Patients: Avoiding Iatrogenic Anemia.American journal of respiratory and critical care medicine, , More Information

Duggal, Abhijit; Panitchote, Anupol; Siuba, Matthew; Krishnan, Sudhir; Torbic, Heather; Hastings, Andrei; Mehkri, Omar; Hanane, Tarik; Hatipoglu, Umur; Hite, R Duncan; Mireles-Cabodevila, Eduardo (2020. ) Implementation of Protocolized Care in ARDS Improves Outcomes.Respiratory care, , More Information

Smith, Bradford J; Roy, Gregory S; Cleveland, Alyx; Mattson, Courtney; Okamura, Kayo; Charlebois, Chantel M; Hamlington, Katharine L; Novotny, Michael V; Knudsen, Lars; Ochs, Matthias; Hite, R Duncan; Bates, Jason H T (2020. ) Three Alveolar Phenotypes Govern Lung Function in Murine Ventilator-Induced Lung Injury.Frontiers in physiology, , 11 ,660 More Information

Berger, Jeffrey S; Neal, Matthew D; Kornblith, Lucy Z; Gong, Michelle N; Reynolds, Harmony R; Cushman, Mary; Althouse, Andrew D; Lawler, Patrick R; McVerry, Bryan J; Kim, Keri S; Baumann Kreuziger, Lisa; Solomon, Scott D; Kosiborod, Mikhail N; Berry, Scott M; Bochicchio, Grant V; Contoli, Marco; Farkouh, Michael E; Froess, Joshua D; Gandotra, Sheetal; Greenstein, Yonatan; Hade, Erinn M; Hanna, Nicholas; Hudock, Kristin; Hyzy, Robert C; Ibáñez Estéllez, Fátima; Iovine, Nicole; Khanna, Ashish K; Khatri, Pooja; Kirwan, Bridget-Anne; Kutcher, Matthew E; Leifer, Eric; Lim, George; Lopes, Renato D; Lopez-Sendon, Jose L; Luther, James F; Nigro Maia, Lilia; Quigley, John G; Wahid, Lana; Wilson, Jennifer G; Zarychanski, Ryan; Kindzelski, Andrei; Geraci, Mark W; Hochman, Judith S (2023. ) Effect of P2Y12 Inhibitors on Organ Support-Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial.JAMA network open, , 6 (5 ) ,e2314428 More Information

Self, Wesley H; Shotwell, Matthew S; Gibbs, Kevin W; de Wit, Marjolein; Files, D Clark; Harkins, Michelle; Hudock, Kristin M; Merck, Lisa H; Moskowitz, Ari; Apodaca, Krystle D; Barksdale, Aaron; Safdar, Basmah; Javaheri, Ali; Sturek, Jeffrey M; Schrager, Harry; Iovine, Nicole; Tiffany, Brian; Douglas, Ivor S; Levitt, Joseph; Busse, Laurence W; Ginde, Adit A; Brown, Samuel M; Hager, David N; Boyle, Katherine; Duggal, Abhijit; Khan, Akram; Lanspa, Michael; Chen, Peter; Puskarich, Michael; Vonderhaar, Derek; Venkateshaiah, Lokesh; Gentile, Nina; Rosenberg, Yves; Troendle, James; Bistran-Hall, Amanda J; DeClercq, Josh; Lavieri, Robert; Joly, Meghan Morrison; Orr, Michael; Pulley, Jill; Rice, Todd W; Schildcrout, Jonathan S; Semler, Matthew W; Wang, Li; Bernard, Gordon R; Collins, Sean P (2023. ) Renin-Angiotensin System Modulation With Synthetic Angiotensin (1-7) and Angiotensin II Type 1 Receptor-Biased Ligand in Adults With COVID-19: Two Randomized Clinical Trials.JAMA, , 329 (14 ) ,1170-1182 More Information

Williams Roberson, Shawniqua; Nwosu, Samuel; Collar, Erin M; Kiehl, Amy L; Harrison, Fiona E; Bastarache, Julie; Wilson, Jo Ellen; Mart, Matthew F; Sevransky, Jonathan E; Ely, E Wesley; Lindsell, Christopher J; Jackson, James C (2023. ) Association of Vitamin C, Thiamine, and Hydrocortisone Infusion With Long-term Cognitive, Psychological, and Functional Outcomes in Sepsis Survivors: A Secondary Analysis of the Vitamin C, Thiamine, and Steroids in Sepsis Randomized Clinical Trial.JAMA network open, , 6 (2 ) ,e230380 More Information

Qiao, Xian; Kashiouris, Markos G; L'Heureux, Michael; Fisher, Bernard J; Leichtle, Stefan W; Truwit, Jonathon D; Nanchal, Rahul; Hite, Robert Duncan; Morris, Peter E; Martin, Greg S; Sevransky, Jonathan; Fowler, Alpha A (2022. ) Biological Effects of Intravenous Vitamin C on Neutrophil Extracellular Traps and the Endothelial Glycocalyx in Patients with Sepsis-Induced ARDS.Nutrients, , 14 (20 ) , More Information

, ; Goligher, Ewan C; Bradbury, Charlotte A; McVerry, Bryan J; Lawler, Patrick R; Berger, Jeffrey S; Gong, Michelle N; Carrier, Marc; Reynolds, Harmony R; Kumar, Anand; Turgeon, Alexis F; Kornblith, Lucy Z; Kahn, Susan R; Marshall, John C; Kim, Keri S; Houston, Brett L; Derde, Lennie P G; Cushman, Mary; Tritschler, Tobias; Angus, Derek C; Godoy, Lucas C; McQuilten, Zoe; Kirwan, Bridget-Anne; Farkouh, Michael E; Brooks, Maria M; Lewis, Roger J; Berry, Lindsay R; Lorenzi, Elizabeth; Gordon, Anthony C; Ahuja, Tania; Al-Beidh, Farah; Annane, Djillali; Arabi, Yaseen M; Aryal, Diptesh; Baumann Kreuziger, Lisa; Beane, Abi; Bhimani, Zahra; Bihari, Shailesh; Billett, Henny H; Bond, Lindsay; Bonten, Marc; Brunkhorst, Frank; Buxton, Meredith; Buzgau, Adrian; Castellucci, Lana A; Chekuri, Sweta; Chen, Jen-Ting; Cheng, Allen C; Chkhikvadze, Tamta; Coiffard, Benjamin; Contreras, Aira; Costantini, Todd W; de Brouwer, Sophie; Detry, Michelle A; Duggal, Abhijit; Džavík, Vladimír; Effron, Mark B; Eng, Heather F; Escobedo, Jorge; Estcourt, Lise J; Everett, Brendan M; Fergusson, Dean A; Fitzgerald, Mark; Fowler, Robert A; Froess, Joshua D; Fu, Zhuxuan; Galanaud, Jean P; Galen, Benjamin T; Gandotra, Sheetal; Girard, Timothy D; Goodman, Andrew L; Goossens, Herman; Green, Cameron; Greenstein, Yonatan Y; Gross, Peter L; Haniffa, Rashan; Hegde, Sheila M; Hendrickson, Carolyn M; Higgins, Alisa M; Hindenburg, Alexander A; Hope, Aluko A; Horowitz, James M; Horvat, Christopher M; Huang, David T; Hudock, Kristin; Hunt, Beverley J; Husain, Mansoor; Hyzy, Robert C; Jacobson, Jeffrey R; Jayakumar, Devachandran; Keller, Norma M; Khan, Akram; Kim, Yuri; Kindzelski, Andrei; King, Andrew J; Knudson, M Margaret; Kornblith, Aaron E; Kutcher, Matthew E; Laffan, Michael A; Lamontagne, Francois; Le Gal, Grégoire; Leeper, Christine M; Leifer, Eric S; Lim, George; Gallego Lima, Felipe; Linstrum, Kelsey; Litton, Edward; Lopez-Sendon, Jose; Lother, Sylvain A; Marten, Nicole; Saud Marinez, Andréa; Martinez, Mary; Mateos Garcia, Eduardo; Mavromichalis, Stavroula; McAuley, Daniel F; McDonald, Emily G; McGlothlin, Anna; McGuinness, Shay P; Middeldorp, Saskia; Montgomery, Stephanie K; Mouncey, Paul R; Murthy, Srinivas; Nair, Girish B; Nair, Rahul; Nichol, Alistair D; Nicolau, Jose C; Nunez-Garcia, Brenda; Park, John J; Park, Pauline K; Parke, Rachael L; Parker, Jane C; Parnia, Sam; Paul, Jonathan D; Pompilio, Mauricio; Quigley, John G; Rosenson, Robert S; Rost, Natalia S; Rowan, Kathryn; Santos, Fernanda O; Santos, Marlene; Santos, Mayler O; Satterwhite, Lewis; Saunders, Christina T; Schreiber, Jake; Schutgens, Roger E G; Seymour, Christopher W; Siegal, Deborah M; Silva, Delcio G; Singhal, Aneesh B; Slutsky, Arthur S; Solvason, Dayna; Stanworth, Simon J; Turner, Anne M; van Bentum-Puijk, Wilma; van de Veerdonk, Frank L; van Diepen, Sean; Vazquez-Grande, Gloria; Wahid, Lana; Wareham, Vanessa; Widmer, R Jay; Wilson, Jennifer G; Yuriditsky, Eugene; Zhong, Yongqi; Berry, Scott M; McArthur, Colin J; Neal, Matthew D; Hochman, Judith S; Webb, Steven A; Zarychanski, Ryan (2021. ) Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19.The New England journal of medicine, , 385 (9 ) ,777-789 More Information

, ; Lawler, Patrick R; Goligher, Ewan C; Berger, Jeffrey S; Neal, Matthew D; McVerry, Bryan J; Nicolau, Jose C; Gong, Michelle N; Carrier, Marc; Rosenson, Robert S; Reynolds, Harmony R; Turgeon, Alexis F; Escobedo, Jorge; Huang, David T; Bradbury, Charlotte A; Houston, Brett L; Kornblith, Lucy Z; Kumar, Anand; Kahn, Susan R; Cushman, Mary; McQuilten, Zoe; Slutsky, Arthur S; Kim, Keri S; Gordon, Anthony C; Kirwan, Bridget-Anne; Brooks, Maria M; Higgins, Alisa M; Lewis, Roger J; Lorenzi, Elizabeth; Berry, Scott M; Berry, Lindsay R; Aday, Aaron W; Al-Beidh, Farah; Annane, Djillali; Arabi, Yaseen M; Aryal, Diptesh; Baumann Kreuziger, Lisa; Beane, Abi; Bhimani, Zahra; Bihari, Shailesh; Billett, Henny H; Bond, Lindsay; Bonten, Marc; Brunkhorst, Frank; Buxton, Meredith; Buzgau, Adrian; Castellucci, Lana A; Chekuri, Sweta; Chen, Jen-Ting; Cheng, Allen C; Chkhikvadze, Tamta; Coiffard, Benjamin; Costantini, Todd W; de Brouwer, Sophie; Derde, Lennie P G; Detry, Michelle A; Duggal, Abhijit; Džavík, Vladimír; Effron, Mark B; Estcourt, Lise J; Everett, Brendan M; Fergusson, Dean A; Fitzgerald, Mark; Fowler, Robert A; Galanaud, Jean P; Galen, Benjamin T; Gandotra, Sheetal; García-Madrona, Sebastian; Girard, Timothy D; Godoy, Lucas C; Goodman, Andrew L; Goossens, Herman; Green, Cameron; Greenstein, Yonatan Y; Gross, Peter L; Hamburg, Naomi M; Haniffa, Rashan; Hanna, George; Hanna, Nicholas; Hegde, Sheila M; Hendrickson, Carolyn M; Hite, R Duncan; Hindenburg, Alexander A; Hope, Aluko A; Horowitz, James M; Horvat, Christopher M; Hudock, Kristin; Hunt, Beverley J; Husain, Mansoor; Hyzy, Robert C; Iyer, Vivek N; Jacobson, Jeffrey R; Jayakumar, Devachandran; Keller, Norma M; Khan, Akram; Kim, Yuri; Kindzelski, Andrei L; King, Andrew J; Knudson, M Margaret; Kornblith, Aaron E; Krishnan, Vidya; Kutcher, Matthew E; Laffan, Michael A; Lamontagne, Francois; Le Gal, Grégoire; Leeper, Christine M; Leifer, Eric S; Lim, George; Lima, Felipe Gallego; Linstrum, Kelsey; Litton, Edward; Lopez-Sendon, Jose; Lopez-Sendon Moreno, Jose L; Lother, Sylvain A; Malhotra, Saurabh; Marcos, Miguel; Saud Marinez, Andréa; Marshall, John C; Marten, Nicole; Matthay, Michael A; McAuley, Daniel F; McDonald, Emily G; McGlothlin, Anna; McGuinness, Shay P; Middeldorp, Saskia; Montgomery, Stephanie K; Moore, Steven C; Morillo Guerrero, Raquel; Mouncey, Paul R; Murthy, Srinivas; Nair, Girish B; Nair, Rahul; Nichol, Alistair D; Nunez-Garcia, Brenda; Pandey, Ambarish; Park, Pauline K; Parke, Rachael L; Parker, Jane C; Parnia, Sam; Paul, Jonathan D; Pérez González, Yessica S; Pompilio, Mauricio; Prekker, Matthew E; Quigley, John G; Rost, Natalia S; Rowan, Kathryn; Santos, Fernanda O; Santos, Marlene; Olombrada Santos, Mayler; Satterwhite, Lewis; Saunders, Christina T; Schutgens, Roger E G; Seymour, Christopher W; Siegal, Deborah M; Silva, Delcio G; Shankar-Hari, Manu; Sheehan, John P; Singhal, Aneesh B; Solvason, Dayna; Stanworth, Simon J; Tritschler, Tobias; Turner, Anne M; van Bentum-Puijk, Wilma; van de Veerdonk, Frank L; van Diepen, Sean; Vazquez-Grande, Gloria; Wahid, Lana; Wareham, Vanessa; Wells, Bryan J; Widmer, R Jay; Wilson, Jennifer G; Yuriditsky, Eugene; Zampieri, Fernando G; Angus, Derek C; McArthur, Colin J; Webb, Steven A; Farkouh, Michael E; Hochman, Judith S; Zarychanski, Ryan (2021. ) Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.The New England journal of medicine, , 385 (9 ) ,790-802 More Information

Lee, Hyunwook; Fei, Qinqin; Streicher, Adam; Zhang, Wenjuan; Isabelle, Colleen; Patel, Pragi; Lam, Hilaire C; Arciniegas-Rubio, Antonio; Pinilla-Vera, Miguel; Amador-Munoz, Diana P; Barragan-Bradford, Diana; Higuera-Moreno, Angelica; Putman, Rachel K; Sholl, Lynette M; Henske, Elizabeth P; Bobba, Christopher M; Higuita-Castro, Natalia; Shalosky, Emily M; Hite, R Duncan; Christman, John W; Ghadiali, Samir N; Baron, Rebecca M; Englert, Joshua A (2021. ) mTORC1 is a mechanosensor that regulates surfactant function and lung compliance during ventilator-induced lung injury.JCI insight, , 6 (14 ) , More Information

Rosas, Lucia E; Doolittle, Lauren M; Joseph, Lisa M; El-Musa, Hasan; Novotny, Michael V; Hickman-Davis, Judy M; Hite, R Duncan; Davis, Ian C (2021. ) Postexposure Liponucleotide Prophylaxis and Treatment Attenuates Acute Respiratory Distress Syndrome in Influenza-infected Mice.American journal of respiratory cell and molecular biology, , 64 (6 ) ,677-686 More Information

Murphy, Ryan C; Lai, Ying; Nolin, James D; Aguillon Prada, Robier A; Chakrabarti, Arindam; Novotny, Michael V; Seeds, Michael C; Altemeier, William A; Gelb, Michael H; Hite, Robert Duncan; Hallstrand, Teal S (2021. ) Exercise-induced alterations in phospholipid hydrolysis, airway surfactant, and eicosanoids and their role in airway hyperresponsiveness in asthma.American journal of physiology. Lung cellular and molecular physiology, , 320 (5 ) ,L705-L714 More Information

Hite, R Duncan; Davis, Ian C (2021. ) You Are What You Eat: Diet-Dependent Changes in Pulmonary Surfactant.American journal of respiratory cell and molecular biology, , 64 (3 ) ,281-282 More Information

Sevransky, Jonathan E; Rothman, Richard E; Hager, David N; Bernard, Gordon R; Brown, Samuel M; Buchman, Timothy G; Busse, Laurence W; Coopersmith, Craig M; DeWilde, Christine; Ely, E Wesley; Eyzaguirre, Lindsay M; Fowler, Alpha A; Gaieski, David F; Gong, Michelle N; Hall, Alex; Hinson, Jeremiah S; Hooper, Michael H; Kelen, Gabor D; Khan, Akram; Levine, Mark A; Lewis, Roger J; Lindsell, Chris J; Marlin, Jessica S; McGlothlin, Anna; Moore, Brooks L; Nugent, Katherine L; Nwosu, Samuel; Polito, Carmen C; Rice, Todd W; Ricketts, Erin P; Rudolph, Caroline C; Sanfilippo, Fred; Viele, Kert; Martin, Greg S; Wright, David W (2021. ) Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial.JAMA, , 325 (8 ) ,742-750 More Information

Academic - COM - Internal Medicine-Pulmonary - 0564
231 Albert Sabin Way, MSB 6165
Cincinnati  Ohio, 45267
Phone: (513) 558-4831
Fax: 513-558-4858
hitern@uc.edu