Katherine Holland-Bouley , MD,PhD

Medical Degree: Washington University St. Louis, MO,

Doctoral Degree: Washington University St. Louis, MO, (Pharmacology)

Internship: Boston Children's Hospital Boston, MA, (Pediatrics)

Residency: St Louis Children's Hospital Boston, MA, (Pediatric Neurology)

Mechanisms of Epileptogenisis

Peer Reviewed Publications

Greiner, Hansel M; Holland, Katherine; Leach, James L; Horn, Paul S; Hershey, Andrew D; Rose, Douglas F (2012. ) Nonconvulsive Status Epilepticus: The Encephalopathic Pediatric Patient.Pediatrics, , More Information

Greiner, Hansel M; Tillema, Jan-Mendelt; Hallinan, Barbara E; Holland, Katherine; Lee, Ki-Hyeong; Crone, Kerry R (2012. ) Corpus callosotomy for treatment of pediatric refractory status epilepticus.Seizure : the journal of the British Epilepsy Association, , More Information

Greiner, Hansel M; Park, Yong D; Holland, Katherine; Horn, Paul S; Byars, Anna W; Mangano, Francesco T; Smith, Joseph R; Lee, Mark R; Lee, Ki-Hyeong (2011. ) Scalp EEG does not predict hemispherectomy outcome.Seizure : the journal of the British Epilepsy Association, , 20 (10 ) ,758-63 More Information

Fountain-Capal, Jamie K; Holland, Katherine D; Gilbert, Donald L; Hallinan, Barbara E (2011. ) When should clinicians order genetic testing for Dravet syndrome?.Pediatric neurology, , 45 (5 ) ,319-23 More Information

Krueger, Darcy A; Care, Marguerite M; Holland, Katherine; Agricola, Karen; Tudor, Cynthia; Mangeshkar, Prajakta; Wilson, Kimberly A; Byars, Anna; Sahmoud, Tarek; Franz, David Neal (2010. ) Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis.The New England journal of medicine, , 363 (19 ) ,1801-11 More Information

Holland, Katherine D; Hallinan, Barbara E (2010. ) What causes epileptic encephalopathy in infancy?: the answer may lie in our genes.Neurology, , 75 (13 ) ,1132-3 More Information

Standridge, Shannon M; Holland, Katherine D; Horn, Paul S (2010. ) Cardiac arrhythmias and ictal events within an epilepsy monitoring unit.Pediatric neurology, , 42 (3 ) ,201-5 More Information

Holland, Katherine; Kaye, Andrew H (2009. ) Spinal tumors in neurofibromatosis-2: management considerations - a review.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, , 16 (2 ) ,169-77 More Information

Holland, Katherine D (2008. ) SCN1A variant in a Scandinavian GEFS+ family: a wolf in sheep's clothing?.Acta neurologica Scandinavica, , 118 (5 ) ,344-5; author reply More Information

Holland, Katherine D; Buchhalter, Jeffrey (2008. ) Hemiconvulsion-hemiplegia-epilepsy syndrome: another case for epilepsy surgery.Neurology, , 70 (22 Pt 2 ) ,2097-8 More Information

Lachhwani, Deepak K; Loddenkemper, Tobias; Holland, Katherine D; Kotagal, Prakash; Mascha, Edward; Bingaman, William; Wyllie, Elaine (2008. ) Discontinuation of medications after successful epilepsy surgery in children.Pediatric neurology, , 38 (5 ) ,340-4 More Information

Holland, Katherine D; Kearney, Jennifer A; Glauser, Tracy A; Buck, Gerri; Keddache, Mehdi; Blankston, John R; Glaaser, Ian W; Kass, Robert S; Meisler, Miriam H (2008. ) Mutation of sodium channel SCN3A in a patient with cryptogenic pediatric partial epilepsy.Neuroscience letters, , 433 (1 ) ,65-70 More Information

Holland, Katherine D; Glauser, Tracy A (2007. ) Response to carbamazepine in children with newly diagnosed partial onset epilepsy.Neurology, , 69 (6 ) ,596-9 More Information

Levisohn, Paul M; Holland, Katherine D (2007. ) Topiramate or valproate in patients with juvenile myoclonic epilepsy: a randomized open-label comparison.Epilepsy & behavior : E&B, , 10 (4 ) ,547-52 More Information

Loddenkemper, Tobias; Holland, Katherine D; Stanford, Lisa D; Kotagal, Prakash; Bingaman, William; Wyllie, Elaine (2007. ) Developmental outcome after epilepsy surgery in infancy.Pediatrics, , 119 (5 ) ,930-5 More Information

Holland, Katherine D; Fleming, Michelle T; Cheek, Susannah; Moran, Jennifer L; Beier, David R; Meisler, Miriam H (2006. ) De novo exon duplication in a new allele of mouse Glra1 (spasmodic).Genetics, , 174 (4 ) ,2245-7 More Information

Chapman, Kevin; Holland, Katherine; Erenberg, Gerald (2003. ) Seizure exacerbation associated with oxcarbazepine in idiopathic focal epilepsy of childhood. Neurology, , 61 (7 ) ,1012-3

Holland, Katherine D; Wyllie, Elaine (2002. ) Outcome after surgical treatment. Neurosurgery clinics of North America, , 13 (1 ) ,135-44, ix

Jain, Sejal V; Horn, Paul S; Simakajornboon, Narong; Beebe, Dean W; Holland, Katherine; Byars, Anna W; Glauser, Tracy A (2015. ) Melatonin improves sleep in children with epilepsy: a randomized, double-blind, crossover study.Sleep medicine, , 16 (5 ) ,637-44 More Information

Greiner, Mary V; Greiner, Hansel M; Caré, Marguerite M; Owens, Deanna; Shapiro, Robert; Holland, Katherine (2015. ) Adding Insult to Injury: Nonconvulsive Seizures in Abusive Head Trauma.Journal of child neurology, , More Information

Arya, Ravindra; Wilson, J Adam; Vannest, Jennifer; Byars, Anna W; Greiner, Hansel M; Buroker, Jason; Fujiwara, Hisako; Mangano, Francesco T; Holland, Katherine D; Horn, Paul S; Crone, Nathan E; Rose, Douglas F (2015. ) Electrocorticographic language mapping in children by high-gamma synchronization during spontaneous conversation: comparison with conventional electrical cortical stimulation.Epilepsy research, , 110 ,78-87 More Information

Arya, Ravindra; Tenney, Jeffrey R; Horn, Paul S; Greiner, Hansel M; Holland, Katherine D; Leach, James L; Gelfand, Michael J; Rozhkov, Leonid; Fujiwara, Hisako; Rose, Douglas F; Franz, David N; Mangano, Francesco T (2015. ) Long-term outcomes of resective epilepsy surgery after invasive presurgical evaluation in children with tuberous sclerosis complex and bilateral multiple lesions.Journal of neurosurgery. Pediatrics, , 15 (1 ) ,26-33 More Information

Jiang, Yifei; Pun, Raymund Y K; Peariso, Katrina; Holland, Katherine D; Lian, Qingquan; Danzer, Steve C (2015. ) Olfactory Bulbectomy Leads to the Development of Epilepsy in Mice.PloS one, , 10 (9 ) ,e0138178 More Information

Arya, Ravindra; Greiner, Hansel M; Lewis, Amanda; Horn, Paul S; Mangano, Francesco T; Gonsalves, Cornelia; Holland, Katherine D (2014. ) Predictors of response to vagus nerve stimulation in childhood-onset medically refractory epilepsy.Journal of child neurology, , 29 (12 ) ,1652-9 More Information

Arya, Ravindra; Greiner, Hansel M; Horn, Paul S; Turner, Michele; Holland, Katherine D; Mangano, Francesco T (2014. ) Corpus callosotomy for childhood-onset drug-resistant epilepsy unresponsive to vagus nerve stimulation.Pediatric neurology, , 51 (6 ) ,800-5 More Information

Xiang, Jing; Tenney, Jeffrey R; Korman, Abraham M; Leiken, Kimberly; Rose, Douglas F; Harris, Elana; Yuan, Weihong; Horn, Paul S; Holland, Katherine; Loring, David W; Glauser, Tracy A (2014. ) Quantification of Interictal Neuromagnetic Activity in Absence Epilepsy with Accumulated Source Imaging.Brain topography, , More Information

Brahimaj, Bledi; Greiner, Hansel M; Leach, James L; Horn, Paul S; Stevenson, Charles B; Miles, Lili; Byars, Anna; Holland, Katherine; Sutton, Mary; Mangano, Francesco T (2014. ) The surgical management of pediatric brain tumors causing epilepsy: consideration of the epileptogenic zone.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, , 30 (8 ) ,1383-91 More Information

Leach, James L; Miles, Lili; Henkel, David M; Greiner, Hansel M; Kukreja, Marcia K; Holland, Katherine D; Rose, Douglas F; Zhang, Bin; Mangano, Francesco T (2014. ) Magnetic resonance imaging abnormalities in the resection region correlate with histopathological type, gliosis extent, and postoperative outcome in pediatric cortical dysplasia.Journal of neurosurgery. Pediatrics, , 14 (1 ) ,68-80 More Information

Greiner, Hansel M; Horn, Paul S; Arya, Ravindra; Holland, Katherine; Turner, Michele; Alsaidi, Mohammed H; Leach, James L; Mangano, Francesco T (2014. ) Acute postoperative seizures and long-term outcome following pediatric epilepsy surgery.Seizure, , 23 (6 ) ,483-6 More Information

Vanoye, Carlos G; Gurnett, Christina A; Holland, Katherine D; George, Alfred L; Kearney, Jennifer A (2014. ) Novel SCN3A variants associated with focal epilepsy in children.Neurobiology of disease, , 62 ,313-22 More Information

Arya, Ravindra; Holland, Katherine D (2014. ) In response to comments on Adverse events related to extraoperative invasive EEG monitoring with subdural grid electrodes: a systematic review and meta-analysis.Epilepsia, , 55 (1 ) ,195-6 More Information

Arya, Ravindra; Mangano, Francesco T; Horn, Paul S; Holland, Katherine D; Rose, Douglas F; Glauser, Tracy A (2013. ) Adverse events related to extraoperative invasive EEG monitoring with subdural grid electrodes: a systematic review and meta-analysis.Epilepsia, , 54 (5 ) ,828-39 More Information

Arya, Ravindra; Greiner, Hansel M; Lewis, Amanda; Mangano, Francesco T; Gonsalves, Cornelia; Holland, Katherine D; Glauser, Tracy A (2013. ) Vagus nerve stimulation for medically refractory absence epilepsy.Seizure, , 22 (4 ) ,267-70 More Information

Ngamprasertwong, Pornswan; Michelfelder, Erik C; Arbabi, Shahriar; Choi, Yun Suk; Statile, Christopher; Ding, Lili; Boat, Anne; Eghtesady, Pirooz; Holland, Katherine; Sadhasivam, Senthilkumar (2013. ) Anesthetic techniques for fetal surgery: effects of maternal anesthesia on intraoperative fetal outcomes in a sheep model.Anesthesiology, , 118 (4 ) ,796-808 More Information

Greiner, Hansel M; Horn, Paul S; Holland, Katherine; Collins, James; Hershey, Andrew D; Glauser, Tracy A (2013. ) mRNA blood expression patterns in new-onset idiopathic pediatric epilepsy.Epilepsia, , 54 (2 ) ,272-9 More Information

Pun, Raymund Y K; Rolle, Isaiah J; Lasarge, Candi L; Hosford, Bethany E; Rosen, Jules M; Uhl, Juli D; Schmeltzer, Sarah N; Faulkner, Christian; Bronson, Stefanie L; Murphy, Brian L; Richards, David A; Holland, Katherine D; Danzer, Steve C (2012. ) Excessive activation of mTOR in postnatally generated granule cells is sufficient to cause epilepsy.Neuron, , 75 (6 ) ,1022-34 More Information

Holland, Katherine; Shinnar, Shlomo (2012. ) Status epilepticus in children.Handbook of clinical neurology, , 108 ,795-812 More Information

Graham, Devon L; Herring, Nicole R; Schaefer, Tori L; Holland, Katherine D; Vorhees, Charles V; Williams, Michael T Electroencephalographic and convulsive effects of binge doses of (+)-methamphetamine, 5-methoxydiisopropyltryptamine, and (±)-3,4-methylenedioxymethamphetamine in rats.The open neuropsychopharmacology journal, , 5 ,1-8 More Information

Castro, Olagide W; Santos, Victor R; Pun, Raymund Y K; McKlveen, Jessica M; Batie, Matthew; Holland, Katherine D; Gardner, Margaret; Garcia-Cairasco, Norberto; Herman, James P; Danzer, Steve C (2012. ) Impact of corticosterone treatment on spontaneous seizure frequency and epileptiform activity in mice with chronic epilepsy.PloS one, , 7 (9 ) ,e46044 More Information

American Epilepsy Society

Academic - Cincinnati Children's Hospital Medical Center
Cincinnati  Ohio, 45229
Phone: 513-636-4222
katherine.holland@cchmc.org