Katherine Holland-Bouley, MD, PhD

Medical Degree: Washington University St. Louis, MO,

Doctoral Degree: Washington University St. Louis, MO, (Pharmacology)

Internship: Boston Children's Hospital Boston, MA, (Pediatrics)

Residency: St Louis Children's Hospital Boston, MA, (Pediatric Neurology)

Mechanisms of Epileptogenisis

Peer Reviewed Publications

Greiner, Hansel M; Holland, Katherine; Leach, James L; Horn, Paul S; Hershey, Andrew D; Rose, Douglas F  (2012). Nonconvulsive Status Epilepticus: The Encephalopathic Pediatric Patient. PediatricsMore Information

Greiner, Hansel M; Tillema, Jan-Mendelt; Hallinan, Barbara E; Holland, Katherine; Lee, Ki-Hyeong; Crone, Kerry R  (2012). Corpus callosotomy for treatment of pediatric refractory status epilepticus. Seizure : the journal of the British Epilepsy AssociationMore Information

Greiner, Hansel M; Park, Yong D; Holland, Katherine; Horn, Paul S; Byars, Anna W; Mangano, Francesco T; Smith, Joseph R; Lee, Mark R; Lee, Ki-Hyeong  (2011). Scalp EEG does not predict hemispherectomy outcome. Seizure : the journal of the British Epilepsy Association, 20 (10) , 758-63More Information

Fountain-Capal, Jamie K; Holland, Katherine D; Gilbert, Donald L; Hallinan, Barbara E  (2011). When should clinicians order genetic testing for Dravet syndrome?. Pediatric neurology, 45 (5) , 319-23More Information

Krueger, Darcy A; Care, Marguerite M; Holland, Katherine; Agricola, Karen; Tudor, Cynthia; Mangeshkar, Prajakta; Wilson, Kimberly A; Byars, Anna; Sahmoud, Tarek; Franz, David Neal  (2010). Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis. The New England journal of medicine, 363 (19) , 1801-11More Information

Holland, Katherine D; Hallinan, Barbara E  (2010). What causes epileptic encephalopathy in infancy?: the answer may lie in our genes. Neurology, 75 (13) , 1132-3More Information

Standridge, Shannon M; Holland, Katherine D; Horn, Paul S  (2010). Cardiac arrhythmias and ictal events within an epilepsy monitoring unit. Pediatric neurology, 42 (3) , 201-5More Information

Holland, Katherine; Kaye, Andrew H  (2009). Spinal tumors in neurofibromatosis-2: management considerations - a review. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 16 (2) , 169-77More Information

Holland, Katherine D  (2008). SCN1A variant in a Scandinavian GEFS+ family: a wolf in sheep's clothing?. Acta neurologica Scandinavica, 118 (5) , 344-5; author reply More Information

Holland, Katherine D; Buchhalter, Jeffrey  (2008). Hemiconvulsion-hemiplegia-epilepsy syndrome: another case for epilepsy surgery. Neurology, 70 (22 Pt 2) , 2097-8More Information

Lachhwani, Deepak K; Loddenkemper, Tobias; Holland, Katherine D; Kotagal, Prakash; Mascha, Edward; Bingaman, William; Wyllie, Elaine  (2008). Discontinuation of medications after successful epilepsy surgery in children. Pediatric neurology, 38 (5) , 340-4More Information

Holland, Katherine D; Kearney, Jennifer A; Glauser, Tracy A; Buck, Gerri; Keddache, Mehdi; Blankston, John R; Glaaser, Ian W; Kass, Robert S; Meisler, Miriam H  (2008). Mutation of sodium channel SCN3A in a patient with cryptogenic pediatric partial epilepsy. Neuroscience letters, 433 (1) , 65-70More Information

Holland, Katherine D; Glauser, Tracy A  (2007). Response to carbamazepine in children with newly diagnosed partial onset epilepsy. Neurology, 69 (6) , 596-9More Information

Levisohn, Paul M; Holland, Katherine D  (2007). Topiramate or valproate in patients with juvenile myoclonic epilepsy: a randomized open-label comparison. Epilepsy & behavior : E&B, 10 (4) , 547-52More Information

Loddenkemper, Tobias; Holland, Katherine D; Stanford, Lisa D; Kotagal, Prakash; Bingaman, William; Wyllie, Elaine  (2007). Developmental outcome after epilepsy surgery in infancy. Pediatrics, 119 (5) , 930-5More Information

Holland, Katherine D; Fleming, Michelle T; Cheek, Susannah; Moran, Jennifer L; Beier, David R; Meisler, Miriam H  (2006). De novo exon duplication in a new allele of mouse Glra1 (spasmodic). Genetics, 174 (4) , 2245-7More Information

Chapman, Kevin; Holland, Katherine; Erenberg, Gerald  (2003). Seizure exacerbation associated with oxcarbazepine in idiopathic focal epilepsy of childhood. Neurology, 61 (7) , 1012-3

Holland, Katherine D; Wyllie, Elaine  (2002). Outcome after surgical treatment. Neurosurgery clinics of North America, 13 (1) , 135-44, ix

Jain, Sejal V; Horn, Paul S; Simakajornboon, Narong; Beebe, Dean W; Holland, Katherine; Byars, Anna W; Glauser, Tracy A  (2015). Melatonin improves sleep in children with epilepsy: a randomized, double-blind, crossover study. Sleep medicine, 16 (5) , 637-44More Information

Greiner, Mary V; Greiner, Hansel M; Caré, Marguerite M; Owens, Deanna; Shapiro, Robert; Holland, Katherine  (2015). Adding Insult to Injury: Nonconvulsive Seizures in Abusive Head Trauma. Journal of child neurologyMore Information

Arya, Ravindra; Wilson, J Adam; Vannest, Jennifer; Byars, Anna W; Greiner, Hansel M; Buroker, Jason; Fujiwara, Hisako; Mangano, Francesco T; Holland, Katherine D; Horn, Paul S; Crone, Nathan E; Rose, Douglas F  (2015). Electrocorticographic language mapping in children by high-gamma synchronization during spontaneous conversation: comparison with conventional electrical cortical stimulation. Epilepsy research, 110, 78-87More Information

Arya, Ravindra; Tenney, Jeffrey R; Horn, Paul S; Greiner, Hansel M; Holland, Katherine D; Leach, James L; Gelfand, Michael J; Rozhkov, Leonid; Fujiwara, Hisako; Rose, Douglas F; Franz, David N; Mangano, Francesco T  (2015). Long-term outcomes of resective epilepsy surgery after invasive presurgical evaluation in children with tuberous sclerosis complex and bilateral multiple lesions. Journal of neurosurgery. Pediatrics, 15 (1) , 26-33More Information

Jiang, Yifei; Pun, Raymund Y K; Peariso, Katrina; Holland, Katherine D; Lian, Qingquan; Danzer, Steve C  (2015). Olfactory Bulbectomy Leads to the Development of Epilepsy in Mice. PloS one, 10 (9) , e0138178More Information

Arya, Ravindra; Greiner, Hansel M; Lewis, Amanda; Horn, Paul S; Mangano, Francesco T; Gonsalves, Cornelia; Holland, Katherine D  (2014). Predictors of response to vagus nerve stimulation in childhood-onset medically refractory epilepsy. Journal of child neurology, 29 (12) , 1652-9More Information

Arya, Ravindra; Greiner, Hansel M; Horn, Paul S; Turner, Michele; Holland, Katherine D; Mangano, Francesco T  (2014). Corpus callosotomy for childhood-onset drug-resistant epilepsy unresponsive to vagus nerve stimulation. Pediatric neurology, 51 (6) , 800-5More Information

Xiang, Jing; Tenney, Jeffrey R; Korman, Abraham M; Leiken, Kimberly; Rose, Douglas F; Harris, Elana; Yuan, Weihong; Horn, Paul S; Holland, Katherine; Loring, David W; Glauser, Tracy A  (2014). Quantification of Interictal Neuromagnetic Activity in Absence Epilepsy with Accumulated Source Imaging. Brain topographyMore Information

Brahimaj, Bledi; Greiner, Hansel M; Leach, James L; Horn, Paul S; Stevenson, Charles B; Miles, Lili; Byars, Anna; Holland, Katherine; Sutton, Mary; Mangano, Francesco T  (2014). The surgical management of pediatric brain tumors causing epilepsy: consideration of the epileptogenic zone. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 30 (8) , 1383-91More Information

Leach, James L; Miles, Lili; Henkel, David M; Greiner, Hansel M; Kukreja, Marcia K; Holland, Katherine D; Rose, Douglas F; Zhang, Bin; Mangano, Francesco T  (2014). Magnetic resonance imaging abnormalities in the resection region correlate with histopathological type, gliosis extent, and postoperative outcome in pediatric cortical dysplasia. Journal of neurosurgery. Pediatrics, 14 (1) , 68-80More Information

Greiner, Hansel M; Horn, Paul S; Arya, Ravindra; Holland, Katherine; Turner, Michele; Alsaidi, Mohammed H; Leach, James L; Mangano, Francesco T  (2014). Acute postoperative seizures and long-term outcome following pediatric epilepsy surgery. Seizure, 23 (6) , 483-6More Information

Vanoye, Carlos G; Gurnett, Christina A; Holland, Katherine D; George, Alfred L; Kearney, Jennifer A  (2014). Novel SCN3A variants associated with focal epilepsy in children. Neurobiology of disease, 62, 313-22More Information

Arya, Ravindra; Holland, Katherine D  (2014). In response to comments on Adverse events related to extraoperative invasive EEG monitoring with subdural grid electrodes: a systematic review and meta-analysis. Epilepsia, 55 (1) , 195-6More Information

Arya, Ravindra; Mangano, Francesco T; Horn, Paul S; Holland, Katherine D; Rose, Douglas F; Glauser, Tracy A  (2013). Adverse events related to extraoperative invasive EEG monitoring with subdural grid electrodes: a systematic review and meta-analysis. Epilepsia, 54 (5) , 828-39More Information

Arya, Ravindra; Greiner, Hansel M; Lewis, Amanda; Mangano, Francesco T; Gonsalves, Cornelia; Holland, Katherine D; Glauser, Tracy A  (2013). Vagus nerve stimulation for medically refractory absence epilepsy. Seizure, 22 (4) , 267-70More Information

Ngamprasertwong, Pornswan; Michelfelder, Erik C; Arbabi, Shahriar; Choi, Yun Suk; Statile, Christopher; Ding, Lili; Boat, Anne; Eghtesady, Pirooz; Holland, Katherine; Sadhasivam, Senthilkumar  (2013). Anesthetic techniques for fetal surgery: effects of maternal anesthesia on intraoperative fetal outcomes in a sheep model. Anesthesiology, 118 (4) , 796-808More Information

Greiner, Hansel M; Horn, Paul S; Holland, Katherine; Collins, James; Hershey, Andrew D; Glauser, Tracy A  (2013). mRNA blood expression patterns in new-onset idiopathic pediatric epilepsy. Epilepsia, 54 (2) , 272-9More Information

Pun, Raymund Y K; Rolle, Isaiah J; Lasarge, Candi L; Hosford, Bethany E; Rosen, Jules M; Uhl, Juli D; Schmeltzer, Sarah N; Faulkner, Christian; Bronson, Stefanie L; Murphy, Brian L; Richards, David A; Holland, Katherine D; Danzer, Steve C  (2012). Excessive activation of mTOR in postnatally generated granule cells is sufficient to cause epilepsy. Neuron, 75 (6) , 1022-34More Information

Holland, Katherine; Shinnar, Shlomo  (2012). Status epilepticus in children. Handbook of clinical neurology, 108, 795-812More Information

Graham, Devon L; Herring, Nicole R; Schaefer, Tori L; Holland, Katherine D; Vorhees, Charles V; Williams, Michael TElectroencephalographic and convulsive effects of binge doses of (+)-methamphetamine, 5-methoxydiisopropyltryptamine, and (±)-3,4-methylenedioxymethamphetamine in rats. The open neuropsychopharmacology journal, 5, 1-8More Information

Castro, Olagide W; Santos, Victor R; Pun, Raymund Y K; McKlveen, Jessica M; Batie, Matthew; Holland, Katherine D; Gardner, Margaret; Garcia-Cairasco, Norberto; Herman, James P; Danzer, Steve C  (2012). Impact of corticosterone treatment on spontaneous seizure frequency and epileptiform activity in mice with chronic epilepsy. PloS one, 7 (9) , e46044More Information

American Epilepsy Society

Academic - Cincinnati Children's Hospital Medical Center
Cincinnati  Ohio, 45229
Phone: 513-636-4222
katherine.holland@cchmc.org