Stacey Huppert

Associate Professor-Affiliate

Childrens Hospital Bldg R

COM Pediatrics Gastroenterology - 0054

Publications

Peer Reviewed Publications

Miethke, Alexander G; Huppert, Stacey S  (2013). Fishing for biliary atresia susceptibility genes. Gastroenterology, 144 (5) , 878-81More Information

Murphy, Andrew J; de Caestecker, Christian; Pierce, Janene; Boyle, Scott C; Ayers, Gregory D; Zhao, Zhiguo; Libes, Jaime M; Correa, Hernan; Walter, Teagan; Huppert, Stacey S; Perantoni, Alan O; de Caestecker, Mark P; Lovvorn, Harold N  (2012). CITED1 expression in liver development and hepatoblastoma. Neoplasia (New York, N.Y.), 14 (12) , 1153-63

Walter, Teagan J; Sparks, Erin E; Huppert, Stacey S  (2012). 3-dimensional resin casting and imaging of mouse portal vein or intrahepatic bile duct system. Journal of visualized experiments : JoVE (68) , e4272More Information

Hang, Brian I; Thorne, Curtis A; Robbins, David J; Huppert, Stacey S; Lee, Laura A; Lee, Ethan  (2012). Screening for small molecule inhibitors of embryonic pathways: sometimes you gotta crack a few eggs. Bioorganic & medicinal chemistry, 20 (6) , 1869-77More Information

Humphreys, Ryan; Zheng, Wei; Prince, Lawrence S; Qu, Xianghu; Brown, Christopher; Loomes, Kathleen; Huppert, Stacey S; Baldwin, Scott; Goudy, Steven  (2012). Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients. Human molecular genetics, 21 (6) , 1374-83More Information

Vanderpool, Charles; Sparks, Erin E; Huppert, Kari A; Gannon, Maureen; Means, Anna L; Huppert, Stacey S  (2012). Genetic interactions between hepatocyte nuclear factor-6 and Notch signaling regulate mouse intrahepatic bile duct development in vivo. Hepatology (Baltimore, Md.), 55 (1) , 233-43More Information

Thorne, Curtis A; Lafleur, Bonnie; Lewis, Michelle; Hanson, Alison J; Jernigan, Kristin K; Weaver, David C; Huppert, Kari A; Chen, Tony W; Wichaidit, Chonlarat; Cselenyi, Christopher S; Tahinci, Emilios; Meyers, Kelly C; Waskow, Emily; Orton, Darren; Salic, Adrian; Lee, Laura A; Robbins, David J; Huppert, Stacey S; Lee, Ethan  (2011). A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts. Journal of biomolecular screening, 16 (9) , 995-1006More Information

Huppert, Stacey S  (2011). A new set of classifications for ductal plate malformations. Hepatology (Baltimore, Md.), 53 (6) , 1795-7More Information

Sparks, Erin E; Perrien, Daniel S; Huppert, Kari A; Peterson, Todd E; Huppert, Stacey S  (2011). Defects in hepatic Notch signaling result in disruption of the communicating intrahepatic bile duct network in mice. Disease models & mechanisms, 4 (3) , 359-67More Information

Sparks, Erin E; Huppert, Kari A; Brown, Melanie A; Washington, M Kay; Huppert, Stacey S  (2010). Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice. Hepatology (Baltimore, Md.), 51 (4) , 1391-400More Information

Huppert, Stacey S; Magnuson, Mark A  (2009). New complexity in differentiating stem cells toward hepatic and pancreatic fates. Science signaling, 2 (83) , pe50More Information

Knutson, Sarah K; Chyla, Brenda J; Amann, Joseph M; Bhaskara, Srividya; Huppert, Stacey S; Hiebert, Scott W  (2008). Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks. The EMBO journal, 27 (7) , 1017-28More Information

Vooijs, Marc; Ong, Chin-Tong; Hadland, Brandon; Huppert, Stacey; Liu, Zhenyi; Korving, Jeroen; van den Born, Maaike; Stappenbeck, Thaddeus; Wu, Yumei; Clevers, Hans; Kopan, Raphael  (2007). Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE. Development (Cambridge, England), 134 (3) , 535-44More Information

Chandu, Dilip; Huppert, Stacey S; Kopan, Raphael  (2006). Analysis of transmembrane domain mutants is consistent with sequential cleavage of Notch by gamma-secretase. Journal of neurochemistry, 96 (1) , 228-35More Information

Huppert, Stacey S; Ilagan, Ma Xenia G; De Strooper, Bart; Kopan, Raphael  (2005). Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation. Developmental cell, 8 (5) , 677-88More Information

Hadland, Brandon K; Huppert, Stacey S; Kanungo, Jyotshnabala; Xue, Yingzi; Jiang, Rulang; Gridley, Thomas; Conlon, Ronald A; Cheng, Alec M; Kopan, Raphael; Longmore, Gregory D  (2004). A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. Blood, 104 (10) , 3097-105More Information

Nichols, Amy M; Pan, Yonghua; Herreman, An; Hadland, Brandon K; De Strooper, Bart; Kopan, Raphael; Huppert, Stacey S  (2004). Notch pathway is dispensable for adipocyte specification. Genesis (New York, N.Y. : 2000), 40 (1) , 40-4More Information

Contact Information

stacey.huppert@cchmc.org