Stacey Huppert

Peer Reviewed Publications

Miethke, Alexander G; Huppert, Stacey S (2013. ) Fishing for biliary atresia susceptibility genes.Gastroenterology, , 144 (5 ) ,878-81 More Information

Murphy, Andrew J; de Caestecker, Christian; Pierce, Janene; Boyle, Scott C; Ayers, Gregory D; Zhao, Zhiguo; Libes, Jaime M; Correa, Hernan; Walter, Teagan; Huppert, Stacey S; Perantoni, Alan O; de Caestecker, Mark P; Lovvorn, Harold N (2012. ) CITED1 expression in liver development and hepatoblastoma. Neoplasia (New York, N.Y.), , 14 (12 ) ,1153-63

Walter, Teagan J; Sparks, Erin E; Huppert, Stacey S (2012. ) 3-dimensional resin casting and imaging of mouse portal vein or intrahepatic bile duct system.Journal of visualized experiments : JoVE, , (68 ) ,e4272 More Information

Hang, Brian I; Thorne, Curtis A; Robbins, David J; Huppert, Stacey S; Lee, Laura A; Lee, Ethan (2012. ) Screening for small molecule inhibitors of embryonic pathways: sometimes you gotta crack a few eggs.Bioorganic & medicinal chemistry, , 20 (6 ) ,1869-77 More Information

Humphreys, Ryan; Zheng, Wei; Prince, Lawrence S; Qu, Xianghu; Brown, Christopher; Loomes, Kathleen; Huppert, Stacey S; Baldwin, Scott; Goudy, Steven (2012. ) Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.Human molecular genetics, , 21 (6 ) ,1374-83 More Information

Vanderpool, Charles; Sparks, Erin E; Huppert, Kari A; Gannon, Maureen; Means, Anna L; Huppert, Stacey S (2012. ) Genetic interactions between hepatocyte nuclear factor-6 and Notch signaling regulate mouse intrahepatic bile duct development in vivo.Hepatology (Baltimore, Md.), , 55 (1 ) ,233-43 More Information

Thorne, Curtis A; Lafleur, Bonnie; Lewis, Michelle; Hanson, Alison J; Jernigan, Kristin K; Weaver, David C; Huppert, Kari A; Chen, Tony W; Wichaidit, Chonlarat; Cselenyi, Christopher S; Tahinci, Emilios; Meyers, Kelly C; Waskow, Emily; Orton, Darren; Salic, Adrian; Lee, Laura A; Robbins, David J; Huppert, Stacey S; Lee, Ethan (2011. ) A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts.Journal of biomolecular screening, , 16 (9 ) ,995-1006 More Information

Huppert, Stacey S (2011. ) A new set of classifications for ductal plate malformations.Hepatology (Baltimore, Md.), , 53 (6 ) ,1795-7 More Information

Sparks, Erin E; Perrien, Daniel S; Huppert, Kari A; Peterson, Todd E; Huppert, Stacey S (2011. ) Defects in hepatic Notch signaling result in disruption of the communicating intrahepatic bile duct network in mice.Disease models & mechanisms, , 4 (3 ) ,359-67 More Information

Sparks, Erin E; Huppert, Kari A; Brown, Melanie A; Washington, M Kay; Huppert, Stacey S (2010. ) Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice.Hepatology (Baltimore, Md.), , 51 (4 ) ,1391-400 More Information

Huppert, Stacey S; Magnuson, Mark A (2009. ) New complexity in differentiating stem cells toward hepatic and pancreatic fates.Science signaling, , 2 (83 ) ,pe50 More Information

Knutson, Sarah K; Chyla, Brenda J; Amann, Joseph M; Bhaskara, Srividya; Huppert, Stacey S; Hiebert, Scott W (2008. ) Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks.The EMBO journal, , 27 (7 ) ,1017-28 More Information

Vooijs, Marc; Ong, Chin-Tong; Hadland, Brandon; Huppert, Stacey; Liu, Zhenyi; Korving, Jeroen; van den Born, Maaike; Stappenbeck, Thaddeus; Wu, Yumei; Clevers, Hans; Kopan, Raphael (2007. ) Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE.Development (Cambridge, England), , 134 (3 ) ,535-44 More Information

Chandu, Dilip; Huppert, Stacey S; Kopan, Raphael (2006. ) Analysis of transmembrane domain mutants is consistent with sequential cleavage of Notch by gamma-secretase.Journal of neurochemistry, , 96 (1 ) ,228-35 More Information

Huppert, Stacey S; Ilagan, Ma Xenia G; De Strooper, Bart; Kopan, Raphael (2005. ) Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation.Developmental cell, , 8 (5 ) ,677-88 More Information

Hadland, Brandon K; Huppert, Stacey S; Kanungo, Jyotshnabala; Xue, Yingzi; Jiang, Rulang; Gridley, Thomas; Conlon, Ronald A; Cheng, Alec M; Kopan, Raphael; Longmore, Gregory D (2004. ) A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development.Blood, , 104 (10 ) ,3097-105 More Information

Nichols, Amy M; Pan, Yonghua; Herreman, An; Hadland, Brandon K; De Strooper, Bart; Kopan, Raphael; Huppert, Stacey S (2004. ) Notch pathway is dispensable for adipocyte specification.Genesis (New York, N.Y. : 2000), , 40 (1 ) ,40-4 More Information

stacey.huppert@cchmc.org