Roman Jandarov

Roman A Jandarov

Associate Professor

Kettering Laboratory
Room 146
160 Panzeca Way
Cincinnati, Ohio 45267
Phone 513-558-7975
Email jandarrn@ucmail.uc.edu

Professional Summary

Roman Jandarov, Ph.D.., is an assistant professor of biostatistics and bioinformatics in the Department of Environmental Health at the University of Cincinnati. His current research interests and experience span a range of topics including space-time processes, approaches to dimension reduction, air pollution epidemiology, modeling the dynamics of infectious diseases, complex computer experiments, statistical computing, and Bayesian inference, with applications to biomedical research.
 
Prior to joining the University of Cincinnati, Dr. Jandarov was a postdoctoral senior research fellow in the Department of Biostatistics at the University of Washington. At the University of Washington, his postdoctoral research focused on statistical problems arising in air pollution epidemiology. Dr. Jandarov obtained his Ph.D. from the Department of Statistics at Penn State University in 2012. In his doctoral dissertation, Dr. Jandarov developed inferential methods and statistical tools for infectious disease and population dynamics models and collaborated with leading experts in the field of infectious diseases. Dr. Jandarov also holds a Specialist degree in Mathematics (combined undergraduate and graduate degree equivalent of M.S. in U.S.) from Lomonosov Moscow State University.

Education

Specialist: Lomonosov Moscow State University Moscow, Russia, 2007 (Mathematics: Functional Analysis)

Doctoral Degree: Pennsylvania State University University Park, PA, 2012 (Statistics)

Fellowship: University of Washinton Seattle, WA, 2014 (Center for Clear Air Research projects on the cardiovascular health effects of air pollution)

Research and Practice Interests

Spatial statistics with applications to air pollution studies
 
My students and I develop novel methods and models for statistical dimension reduction and prediction for high dimensional air pollution data. These methods solve issues related to dimensionality and spatial misalignment in health effects studies of exposure to air pollution mixtures. The methods can also be used to obtain exposure estimates in air pollution cohort studies. See related publications below.

Tobacco smoke exposure and related disparities among children and adolescents
 
My team’s extensive publications on tobacco smoke exposure have made it clear that a large proportion of children and adolescents in the U.S. are still exposed to neurotoxicants present in tobacco smoke. We found that the highest rates of tobacco smoke exposure, as measured by serum cotinine, are among children who are non-Hispanic black, have low income, and live in rented homes.
  
Contributions to spatial statistics with applications to infectious diseases
 
I have developed and implemented novel approaches to inference for infectious disease dynamics models with spatiotemporal data. These new approaches focus on the biological characteristics of the dynamical process that are of scientific interest and are based on an approximation to the model using key summary statistics obtained from simulations of the model at differing parameter values. In general, the approach can be useful for a wide array of problems where likelihood functions are intractable or when traditional likelihood-based inference does not produce reasonable estimators or predictions.
 
Child tobacco smoke exposure and related health effects and healthcare utilization patterns
 
I have significant experience in developing and applying statistical methods and tools to analyzing complex original and secondary research data to assess the associations between child tobacco smoke exposure measured using biomarkers and related health effects and healthcare utilization patterns.
 
Contributions to applied functional analysis and the development of statistical applications
 
In the past, I developed optimization methods for solving complex partial differential equations. These methods guaranteed asymptotic convergence of the approximate solutions of the finite dimensional problems to the solution of the infinite dimensional differential equations and outlined strategies for fast implementation of the proposed algorithms.
 

Research Support

Grant: #309186 / R01ES030743 Investigators:Jandarov, Roman; Merianos, Ashley 08-15-2019 -07-31-2024 National Institutes of Health R01 Sub from CCHMC Role:Collaborator $23,125.00 Awarded Level:Federal

Grant: #R01ES027815 Investigators:Mahabee-Gittens 2020 -2022 NIH/NIEHS Contribution of Thirdhand Smoke to Overall Tobacco Smoke Exposure in Pediatric Patients Role:Co-I Active Type:Grant Level:National

Grant: #R01ES030743 Investigators:Mahabee-Gittens 2019 -2024 NIH/NIEHS Prevalence and Correlates of Thirdhand Smoke Exposure in a Pediatric Patient Population Role:Co-I Active Type:Grant Level:National

Grant: #K01DA044313 S1 Investigators:Merianos 2019 -2021 NIH/NIDA Reducing Secondhand Smoke Exposure Among Pediatric Patients in the Emergency Department Setting Role:Co-I Active Type:Grant Level:National

Grant: #K01DA044313 Investigators:Merianos 2017 -2022 NIH/NIDA Reducing Secondhand Smoke Exposure Among Pediatric Patients in the Emergency Department Setting Role:Co-I Active Type:Grant

Grant: #P30ES006096 Investigators:Pinney 2002 -2022 Center for Environmental Genetics (CEG) Role:Co-Director of Pilot Programs Active Type:Grant

Grant: #R21ES032161 Investigators:Jandarov, Roman; Merianos, Ashley 09-01-2020 -08-31-2022 National Institute of Environmental Health Sciences Distinguishing Exposure to Secondhand and Thirdhand Tobacco Smoke and Electronic Cigarettes among U.S. Children based on Multiple Biomarker Profiles Role:Collaborator $266,573.00 Awarded Level:Federal

Grant: #2021 Conquer Cancer Career Development Award Investigators:Gulati, Shuchi; Jandarov, Roman 07-01-2021 -06-30-2024 Conquer Cancer Foundation Combining PD1 Inhibition and Cesium-131 Brachytherapy with Salvage Surgery to Enhance Immunogenicity and Improve Local Control in Head and Neck Cancer Role:Collaborator 200000.00 Active Level:Non Profit

Grant: #W81XWH-21-C-0075 Investigators:Foreman, Brandon; Hartings, Jed; Jandarov, Roman; Ngwenya, Laura 09-20-2021 -09-19-2024 Department of the Army Medical Research Acquisition Activity JW200215 - Improving Neurotrauma by Depolarization Inhibition with Combination Therapy (INDICT): a Phase 2 Randomized Trial Role:Collaborator 0.00 Hold Level:Federal

Grant: #2022 BAF Research Grant Investigators:Jandarov, Roman; Johnson, Mark; Prestigiacomo, Charles; Ralescu, Anca 10-01-2022 -09-30-2023 Brain Aneurysm Foundation Morphological Analysis Through the Use of Fractal Dimension as a Predictor of Cerebral Aneurysm Behavior Role:Collaborator 30000.00 Awarded Level:Non Profit

Publications

Peer Reviewed Publications

Jandarov, R., Haran, M. and Ferrari, M. (2012. ) A compartmental model for meningitis: separating transmission from climate effects on disease incidence .Journal of Agricultural, Biological and Environmental Statistics, , 17 (3 ) ,395-416

Jandarov, R., Haran, M., Bjornstad, O. and Grenfell, B. (2014. ) Emulating a gravity model to infer the spatiotemporal dynamics of an infectious disease .Journal of the Royal Statistical Society: Series C, , 63 (3 ) ,23-444

Merianos, Ashley L; Jandarov, Roman A; Mahabee-Gittens, E Melinda (2018. ) Association of secondhand smoke exposure with asthma symptoms, medication use, and healthcare utilization among asthmatic adolescents.The Journal of asthma : official journal of the Association for the Care of Asthma, , 1-11 More Information

Brokamp, Cole; Jandarov, Roman; Hossain, Monir; Ryan, Patrick (2018. ) Predicting Daily Urban Fine Particulate Matter Concentrations Using a Random Forest Model.Environmental science & technology, , 52 (7 ) ,4173-4179 More Information

Merianos, Ashley L; Jandarov, Roman A; Khoury, Jane C; Mahabee-Gittens, E Melinda (2018. ) Tobacco Smoke Exposure Association With Lipid Profiles and Adiposity Among U.S. Adolescents.The Journal of adolescent health : official publication of the Society for Adolescent Medicine, , 62 (4 ) ,463-470 More Information

Sopirala, Madhuri M; Syed, Asma; Jandarov, Roman; Lewis, Margaret (2018. ) Impact of a change in surveillance definition on performance assessment of a catheter-associated urinary tract infection prevention program at a tertiary care medical center.American journal of infection control, , More Information

Penno, Katie; Jandarov, Roman A; Sopirala, Madhuri M (2017. ) Effect of automated ultraviolet C-emitting device on decontamination of hospital rooms with and without real-time observation of terminal room disinfection.American journal of infection control, , 45 (11 ) ,1208-1213 More Information

Cox, Jennie; Indugula, Reshmi; Vesper, Stephen; Zhu, Zheng; Jandarov, Roman; Reponen, Tiina (2017. ) Comparison of indoor air sampling and dust collection methods for fungal exposure assessment using quantitative PCR.Environmental science. Processes & impacts, , 19 (10 ) ,1312-1319 More Information

Merianos, Ashley L; Jandarov, Roman A; Mahabee-Gittens, E Melinda (2017. ) Secondhand Smoke Exposure and Pediatric Healthcare Visits and Hospitalizations.American journal of preventive medicine, , 53 (4 ) ,441-448 More Information

Brokamp, Cole; Jandarov, Roman; Rao, M B; LeMasters, Grace; Ryan, Patrick (2017. ) Exposure assessment models for elemental components of particulate matter in an urban environment: A comparison of regression and random forest approaches.Atmospheric environment (Oxford, England : 1994), , 151 ,1-11 More Information

Jandarov, Roman A; Sheppard, Lianne A; Sampson, Paul D; Szpiro, Adam A (2017. ) A novel principal component analysis for spatially misaligned multivariate air pollution data.Journal of the Royal Statistical Society. Series C, Applied statistics, , 66 (1 ) ,3-28 More Information

Vangipuram, Ramya; Vaidya, Toral; Jandarov, Roman; Alikhan, Ali (2016. ) Factors Contributing to Depression and Chronic Pain in Patients with Hidradenitis Suppurativa: Results from a Single-Center Retrospective Review.Dermatology (Basel, Switzerland), , 232 (6 ) ,692-695 More Information

Merianos, Ashley L; Jandarov, Roman A; Mahabee-Gittens, E Melinda (2020. ) Tobacco Smoke Exposure, Respiratory Health, and Health-care Utilization Among US Adolescents.Chest, , 158 (3 ) ,1104-1114 More Information

Sengupta, Ruchira; Loftus, Timothy M; Doers, Matthew; Jandarov, Roman A; Phillips, Michael; Ko, Jonathan; Panos, Ralph J; Zafar, Muhammad A (2020. ) Resting Borg score as a predictor of safe discharge of chronic obstructive pulmonary disease from the emergency department observation unit.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, , More Information

Vuong, Ann M; Xie, Changchun; Jandarov, Roman; Dietrich, Kim N; Zhang, Hongmei; Sjödin, Andreas; Calafat, Antonia M; Lanphear, Bruce P; McCandless, Lawrence; Braun, Joseph M; Yolton, Kimberly; Chen, Aimin (2020. ) Prenatal exposure to a mixture of persistent organic pollutants (POPs) and child reading skills at school age.International journal of hygiene and environmental health, , 228 ,113527 More Information

Gupta, Resmi; Khoury, Jane C; Altaye, Mekibib; Jandarov, Roman; Szczesniak, Rhonda D (2020. ) Assessing the Relationship between Gestational Glycemic Control and Risk of Preterm Birth in Women with Type 1 Diabetes: A Joint Modeling Approach.Journal of diabetes research, , 2020 ,3074532 More Information

Cox, Jennie; Ryan, Patrick; Burkle, Jeff; Jandarov, Roman; Mendell, Mark J; Hershey, Gurjit Khurana; LeMasters, Grace; Reponen, Tiina (2020. ) Quantitative and semiquantitative estimates of mold exposure in infancy and childhood respiratory health.Environmental epidemiology (Philadelphia, Pa.), , 4 (4 ) ,e101 More Information

Merianos, Ashley L; Jandarov, Roman A; Gordon, Judith S; Lyons, Michael S; Mahabee-Gittens, E Melinda (2020. ) Child tobacco smoke exposure and healthcare resource utilization patterns.Pediatric research, , More Information

Wajda, Nikolai; Zhu, Zheng; Jandarov, Roman; Dilling, Daniel F; Gupta, Nishant (2020. ) Clinical outcomes and survival following lung transplantation in patients with pulmonary Langerhans cell histiocytosis.Respirology (Carlton, Vic.), , 25 (6 ) ,644-650 More Information

Weber, Danielle E; Held, Justin D; Jandarov, Roman A; Kelleher, Matthew; Kinnear, Ben; Sall, Dana; O'Toole, Jennifer K (2020. ) Development and Establishment of Initial Validity Evidence for a Novel Tool for Assessing Trainee Admission Notes.Journal of general internal medicine, , 35 (4 ) ,1078-1083 More Information

James, Christine; Bernstein, David I; Cox, Jennie; Ryan, Patrick; Wolfe, Christopher; Jandarov, Roman; Newman, Nicholas; Indugula, Reshmi; Reponen, Tiina (2020. ) HEPA filtration improves asthma control in children exposed to traffic-related airborne particles.Indoor air, , 30 (2 ) ,235-243 More Information

Gulati, Shuchi; Desai, Janki; Palackdharry, Sarah M; Morris, John C; Zhu, Zheng; Jandarov, Roman; Riaz, Muhammad K; Takiar, Vinita; Mierzwa, Michelle; Gutkind, J Silvio; Molinolo, Alfredo; Desai, Pankaj B; Sadraei, Nooshin Hashemi; Wise-Draper, Trisha M (2020. ) Phase 1 dose-finding study of metformin in combination with concurrent cisplatin and radiotherapy in patients with locally advanced head and neck squamous cell cancer.Cancer, , 126 (2 ) ,354-362 More Information

Liao, Siyun; Rhodes, Judith; Jandarov, Roman; DeVore, Zachary; Sopirala, Madhuri M (2020. ) Out of Sight-Out of Mind: Impact of Cascade Reporting on Antimicrobial Usage.Open forum infectious diseases, , 7 (2 ) ,ofaa002 More Information

Gangal, Neha S; Hincapie, Ana L; Jandarov, Roman; Frede, Stacey M; Boone, Jill M; MacKinnon, Neil J; Koechlin, Kathleen; DeFiore-Hyrmer, Jolene; Holthusen, Amy; Heaton, Pamela C (2020. ) Association Between a State Law Allowing Pharmacists to Dispense Naloxone Without a Prescription and Naloxone Dispensing Rates.JAMA network open, , 3 (1 ) ,e1920310 More Information

Merianos, Ashley L; Jandarov, Roman A; Klein, Jonathan D; Mahabee-Gittens, E Melinda (2019. ) Characteristics of Daily E-Cigarette Use and Acquisition Means Among a National Sample of Adolescents.American journal of health promotion : AJHP, , 33 (8 ) ,1115-1122 More Information

Chen, Aimin; Jandarov, Roman; Zhou, Li; Calafat, Antonia M; Zhang, Ge; Urbina, Elaine M; Sarac, Jelena; Augustin, Dubravka Havas; Caric, Tonko; Bockor, Luka; Petranovic, Matea Zajc; Novokmet, Natalija; Missoni, Sasa; Rudan, Pavao; Deka, Ranjan (2019. ) Association of perfluoroalkyl substances exposure with cardiometabolic traits in an island population of the eastern Adriatic coast of Croatia.The Science of the total environment, , 683 ,29-36 More Information

Khawar, Muhammad Umair; Yazdani, Dina; Zhu, Zheng; Jandarov, Roman; Dilling, Daniel F; Gupta, Nishant (2019. ) Clinical outcomes and survival following lung transplantation in patients with lymphangioleiomyomatosis.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, , 38 (9 ) ,949-955 More Information

Merianos, Ashley L; Jandarov, Roman A; Choi, Kelvin; Mahabee-Gittens, E Melinda (2019. ) Tobacco smoke exposure disparities persist in U.S. children: NHANES 1999-2014.Preventive medicine, , 123 ,138-142 More Information

Isiugo, Kelechi; Jandarov, Roman; Cox, Jennie; Ryan, Patrick; Newman, Nicholas; Grinshpun, Sergey A; Indugula, Reshmi; Vesper, Steven; Reponen, Tiina (2019. ) Indoor particulate matter and lung function in children.The Science of the total environment, , 663 ,408-417 More Information

Isiugo, Kelechi; Jandarov, Roman; Cox, Jennie; Chillrud, Steve; Grinshpun, Sergey A; Hyttinen, Marko; Yermakov, Michael; Wang, Julian; Ross, James; Reponen, Tiina (2019. ) Predicting Indoor Concentrations of Black Carbon in Residential Environments.Atmospheric environment (Oxford, England : 1994), , 201 ,223-230 More Information

Haque, Sulsal; Karivedu, Vidhya; Riaz, Muhammed K; Choi, David; Roof, Logan; Hassan, Sarah Z; Zhu, Zheng; Jandarov, Roman; Takiar, Vinita; Tang, Alice; Wise-Draper, Trisha (2019. ) High-risk pathological features at the time of salvage surgery predict poor survival after definitive therapy in patients with head and neck squamous cell carcinoma.Oral oncology, , 88 ,9-15 More Information

Haynes, Erin N; Hilbert, Timothy J; Roberts, Rusty; Quirolgico, John; Shepler, Rachael; Beckner, Gerry; Veevers, Jennifer; Burkle, Jeff; Jandarov, Roman (2019. ) Public Participation in Air Sampling and Water Quality Test Kit Development to Enable Citizen Science.Progress in community health partnerships : research, education, and action, , 13 (2 ) ,141-151 More Information

Cox, Jennie; Isiugo, Kelechi; Ryan, Patrick; Grinshpun, Sergey A; Yermakov, Michael; Desmond, Colleen; Jandarov, Roman; Vesper, Stephen; Ross, James; Chillrud, Steven; Dannemiller, Karen; Reponen, Tiina (2018. ) Effectiveness of a portable air cleaner in removing aerosol particles in homes close to highways.Indoor air, , 28 (6 ) ,818-827 More Information

Isiugo, Kelechi; Newman, Nicholas; Jandarov, Roman; Grinshpun, Sergey A; Reponen, Tiina (2018. ) Assessing the accuracy of commercially available gas sensors for the measurement of ambient ozone and nitrogen dioxide.Journal of occupational and environmental hygiene, , 15 (11 ) ,782-791 More Information

Merianos, Ashley L; Jandarov, Roman A; Mahabee-Gittens, E Melinda (2018. ) Adolescent Tobacco Smoke Exposure, Respiratory Symptoms, and Emergency Department Use.Pediatrics, , 142 (3 ) , More Information

Gupta, Resmi; Khoury, Jane C; Altaye, Mekibib; Jandarov, Roman; Szczesniak, Rhonda D (2021. ) Flexible multivariate joint model of longitudinal intensity and binary process for medical monitoring of frequently collected data.Statistics in medicine, , More Information

Merianos, Ashley L; Jandarov, Roman A; Mahabee-Gittens, E Melinda (2020. ) High Cotinine and Healthcare Utilization Disparities Among Low-Income Children.American journal of preventive medicine, , More Information

Newton, Hannah S; Gawali, Vaibhavkumar S; Chimote, Ameet A; Lehn, Maria A; Palackdharry, Sarah M; Hinrichs, Benjamin H; Jandarov, Roman; Hildeman, David; Janssen, Edith M; Wise-Draper, Trisha M; Conforti, Laura (2020. ) PD1 blockade enhances K+ channel activity, Ca2+ signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer.Journal for immunotherapy of cancer, , 8 (2 ) , More Information

Le, Diana T; Barhorst, Kinsey A; Castiglione, James; Yang, George L; Shah, Sanjit J; Harlan, Sarah S; Keegan, Shaun P; Jandarov, Roman A; Ngwenya, Laura B; Prestigiacomo, Charles J (2020. ) Blunt cerebrovascular injury in the geriatric population.Neurosurgical focus, , 49 (4 ) ,E10 More Information

Sall, Dana; Warm, Eric J; Kinnear, Benjamin; Kelleher, Matthew; Jandarov, Roman; O'Toole, Jennifer (2020. ) See One, Do One, Forget One: Early Skill Decay After Paracentesis Training.Journal of general internal medicine, , More Information

Contact Information

Academic - Kettering Laboratory
Room 146
Cincinnati  Ohio, 45267
Phone: 513-558-7975
jandarrn@ucmail.uc.edu