Arun Jose , MD

Dr. Jose graduated from the Johns Hopkins University in 2007, with a bachelors of Science degree in Biomedical Engineering. He then remained at the Johns Hopkins University to complete his medical school degree in 2012, followed by an internal medicine residency at the Johns Hopkins Hospital "Osler" Internal Medicine Program from 2012-2015. He subsequently completed a fellowship in pulmonary and critical care medicine from the George Washington University, before joining the faculty at the University of Cincinnati as a Clinical Instructor, pulmonary hypertension specialist, and IMSTAR fellowship recipient in 2018

His academic interests include the diagnosis and evaluation of pulmonary hypertension, particularly in patients with underlying liver disease, and the pulmonary vascular complications of liver disease (hepatopulmonary syndrome and portopulmonary hypertension). He is currently involved in a number of clinical and translational research projects at the University of Cincinnati, is a member of the PHA, the PVRI, and pulmonary hypertension assemblies of the American Thoracic Society, CHEST, and the International Society of Heart and Lung Transplantation.

Bachelor's Degree: Johns Hopkins University Baltimore, MD, 2007 (Biomedical Engineering)

Doctoral Degree: Johns Hopkins University Baltimore, MD, 2012 (Medicine)

Residency: John Hopkins Hospital Baltimore, MD, 2013 (Internal Medicine)

Residency: Johns Hopkins Hospital Baltimore, MD, 2015 (Internal Medicine)

Fellowship: George Washington University Washington, DC, 2018 (Pulmonary & Critical Care Medicine)

MSCTR: University of Cincinnati Cincinnati, OH, 2019 (Clinical and Translational Research)

American Board of Internal Medicine (Critical Care Medicine) (Certification Date: 11-12-2018 )

American Board of Internal Medicine (Certification Date: 08-05-2015 )

American Board of Internal Medicine (Pulmonary Disease) (Certification Date: 10-19-2017 )

Critical Care Medicine

Lung Disease

Pulmonary Disease

Pulmonary Embolism

Pulmonary Hypertension

Chronic Cough

Dyspnea

Histoplasmosis

Legionnaires' Disease (Legionellosis)

Pleurisy

Pneumonia

Pulmonary Atresia

Pulmonary Heart Disease

Pulmonary Sclerosing Hemangioma

Pulmonary Stenosis

Pulmonary Valve Insufficiency

Pulmonary Valve Stenosis

Pulmonary Vascular Disease (PVD)

Respiration Disorders

Respiratory Syncytial Virus (RSV)

Respiratory Tract Disease

Respiratory Tract Infections

Shortness of Breath

Thoracic Disease

Tuberculosis

Whooping Cough (Pertussis)

Critical Care Medicine

Internal Medicine

Dr. Jose's research and clinical interests include pulmonary vascular diseases such as pulmonary arterial hypertension, an abnormal elevation in the blood pressure in the lungs that can be fatal. He is particularly interested in the complex interplay between pulmonary hypertension and liver disease, and studies portopulmonary hypertension and hepatopulmonary syndrome. 

07-01-2019 -To Present Assistant Professor of Medicine, Assistant professor of medicine and pulmonary hypertension expert at the University of Cincinnati PH Program, University of Cincinnati, Cincinnati, OH

12-01-2019 -To Present Director of Pulmonary Hypertension, Director of PH at the Cincinnati VA Medical Center, Cincinnati VAMC, Cincinnati, OH

07-01-2018 -06-30-2019 Clinical Instructor of Medicine, University of Cincinnati, Cincinnati, OH

Grant: #N/A Investigators:Jose, Arun 07-01-2020 -06-30-2021 UC's Launch Awards Spring Semester (20SS) Research Launch Awards Role:PI $3,500.00 Active Level:Internal UC

Grant: #2021 PBF Fellowship Investigators:Jose, Arun 07-01-2021 -06-30-2024 Parker B. Francis Foundation Biomarker Discovery in Portopulmonary Hypertension Role:PI $225,000.00 Awarded Level:Private Non-Profit

Grant: #Actelion Entelligence Young Investigator Grant Agreement Investigators:Jose, Arun 04-01-2020 -03-31-2021 Actelion Pharmaceuticals US, Inc Biomarker Discovery in Portopulmonary Hypertension Role:PI 100000.00 Hold Level:Industry

Grant: #UL1TR001425 Investigators:A Jose 01-08-2019 -06-01-2021 University of Cincinnati CCTST Diagnostic value of intestinal microbiota in pulmonary arterial hypertension Role:PI 30000 Completed Type:Grant

Grant: #2UL1TR001425-05A1 Investigators:A Jose 04-01-2021 -03-30-2023 NIH and CTSA Biomarker Discovery in Portopulmonary Hypertension Role:PI 80000 Active Type:Grant

Grant: #PHenomenal Impact Fund for Global PH Research Award Agreement Investigators:Jose, Arun 07-01-2022 -06-30-2023 Team Phenomenal Hope, Inc. Circulating gut-derived metabolites as markers of disease severity in PAH Role:PI 50000.00 Hold Level:Non Profit

Grant: #K23HL164971 Investigators:Jose, Arun 04-21-2023 -03-31-2028 National Heart, Lung and Blood Institute Biomarker Discovery in Portopulmonary Hypertension Role:PI 208386.00 Awarded Level:Federal

Peer Reviewed Publications

Jose, Arun; Franco-Palacios, Domingo; King, Christopher S; Gomberg-Maitland, Mardi (2018. ) A 70-Year-Old Woman Presenting With Diarrhea and In-hospital Cardiac Arrest.Chest, , 153 (1 ) ,e5-e8 More Information

Jose, Arun; King, Christopher S; Shlobin, Oksana A; Kiernan, Joseph M; Cossa, Nicolas A; Brown, A Whitney; Nathan, Steven D (2017. ) Ventricular Diastolic Pressure Ratio as a Marker of Treatment Response in Pulmonary Hypertension.Chest, , 152 (5 ) ,980-989 More Information

Jose, Arun; Rafei, Hind; Ahari, Jalil Combination targeted pulmonary hypertension therapy in the resolution of Dasatinib-associated pulmonary arterial hypertension.Pulmonary circulation, , 7 (4 ) ,803-807 More Information

Williams, Jeffrey; McLean, Anna; Ahari, Jalil; Jose, Arun; Al-Helou, Georges; Ibi, Italo; Najam Md, Farzad; Gutierrez, Guillermo (2017. ) Decreases in Mixed Venous Blood O2 Saturation in Cardiac Surgery Patients Following Extubation.Journal of intensive care medicine, , 885066617741435 More Information

Jose, A; Cramer, A K; Davar, K; Gutierrez, G (2017. ) A case of drug-induced lupus erythematosus secondary to trimethoprim/sulfamethoxazole presenting with pleural effusions and pericardial tamponade.Lupus, , 26 (3 ) ,316-319 More Information

Jose A, King CS, Shlobin OA, Brown AW, Wang C, Nathan SD (2018. ) Exercise pulmonary haemodynamic response predicts outcomes in fibrotic lung disease .European respiratory Journal, , 52 (3 ) ,

Jose, Arun; Kher, Akhil; O'Donnell, Robert E; Elwing, Jean M (2020. ) Cardiac magnetic resonance imaging as a prognostic biomarker in treatment-naïve pulmonary hypertension.European journal of radiology, , 123 ,108784 More Information

Jose, Arun; Eckman, Mark H; Elwing, Jean M Anticoagulation in pulmonary arterial hypertension: a decision analysis.Pulmonary circulation, , 9 (4 ) ,2045894019895451 More Information

Jose, Arun; King, Christopher S; Shlobin, Oksana A; Brown, A Whitney; Wang, Chengxi; Nathan, Steven D (2018. ) Exercise pulmonary haemodynamic response predicts outcomes in fibrotic lung disease.The European respiratory journal, , 52 (3 ) , More Information

Arun, Jose; Joseph, Delio; Jonathan, Gwizdala; Hannah, Goulart; Jalil, E Ahari (2018. ) Predictive value of pulmonary function testing in the evaluation of pulmonary hypertension in sarcoidosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, , 35 (4 ) ,308-316 More Information

Jose, Arun; Shah, Shimul A; Anwar, Nadeem; Jones, Courtney R; Sherman, Kenneth E; Elwing, Jean M (2021. ) Pulmonary Vascular Resistance Predicts Mortality and Graft Failure in Transplantation Patients With Portopulmonary Hypertension.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, , 27 (12 ) ,1811-1823 More Information

Jose, Arun; Shah, Shimul A; Anwar, Nadeem; Jones, Courtney R; McCormack, Francis X; Sherman, Kenneth E; Elwing, Jean M (2021. ) Predictors of outcomes following liver transplant in hepatopulmonary syndrome: An OPTN database analysis.Respiratory medicine, , 190 ,106683 More Information

Jose, Arun; Zhou, Christine; Baker, Rachel; Walker, Jackson; Kurek, Nicholas; O'Donnell, Robert E; Elwing, Jean M; Gerson, Myron (2021. ) Predictive value of incidental right ventricular abnormalities identified on SPECT for mortality and pulmonary hypertension.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, , More Information

Morland, Kellie; Gerges, Christian; Elwing, Jean; Visovatti, Scott H; Weatherald, Jason; Gillmeyer, Kari R; Sahay, Sandeep; Mathai, Stephen C; Boucly, Athénaïs; Williams, Paul G; Harikrishnan, Sivadasanpillai; Minty, Evan P; Hobohm, Lukas; Jose, Arun; Badagliacca, Roberto; Lau, Edmund M T; Jing, Zhi-Cheng; Vanderpool, Rebecca R; Fauvel, Charles; Leonidas Alves, Jose; Strange, Geoff; Pulido, Tomas; Qian, Junyan; Li, Mengtao; Mercurio, Valentina; Zelt, Jason G E; Moles, Victor M; Cirulis, Meghan M; Nikkho, Sylvia M; Benza, Raymond L; Elliott, C Gregory (2023. ) Real-world evidence to advance knowledge in pulmonary hypertension: Status, challenges, and opportunities. A consensus statement from the Pulmonary Vascular Research Institute's Innovative Drug Development Initiative's Real-world Evidence Working Group.Pulmonary circulation, , 13 (4 ) ,e12317 More Information

Jose, Arun; Elwing, Jean M; Kawut, Steven M; Pauciulo, Michael W; Sherman, Kenneth E; Nichols, William C; Fallon, Michael B; McCormack, Francis X (2023. ) Human liver single nuclear RNA sequencing implicates BMPR2, GDF15, arginine, and estrogen in portopulmonary hypertension.Communications biology, , 6 (1 ) ,826 More Information

Jose, Arun; Kopras, Elizabeth J; Shah, Shimul A; Elwing, Jean M (2023. ) Portopulmonary hypertension practice patterns after liver transplantation.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, , 29 (4 ) ,365-376 More Information

Jose, Arun; Jones, Courtney R; Elwing, Jean M (2023. ) Struggling Between Liver Transplantation and Portopulmonary Hypertension.Heart failure clinics, , 19 (1 ) ,55-65 More Information

Majeed, Raphael W; Wilkins, Martin R; Howard, Luke; Hassoun, Paul M; Anthi, Anastasia; Cajigas, Hector R; Cannon, John; Chan, Stephen Y; Damonte, Victoria; Elwing, Jean; Förster, Kai; Frantz, Robert; Ghio, Stefano; Al Ghouleh, Imad; Hilgendorff, Anne; Jose, Arun; Juaneda, Ernesto; Kiely, David G; Lawrie, Allan; Orfanos, Stylianos E; Pepe, Antonella; Pepke-Zaba, Joanna; Sirenko, Yuriy; Swett, Andrew J; Torbas, Olena; Zamanian, Roham T; Marquardt, Kurt; Michel-Backofen, Achim; Antoine, Tobiah; Wilhelm, Jochen; Barwick, Stephanie; Krieb, Phillipp; Fuenderich, Meike; Fischer, Patrick; Gall, Henning; Ghofrani, Hossein-Ardeschir; Grimminger, Friedrich; Tello, Khodr; Richter, Manuel J; Seeger, Werner (2022. ) Pulmonary Vascular Research Institute GoDeep: A meta-registry merging deep phenotyping datafrom international PH reference centers.Pulmonary circulation, , 12 (3 ) ,e12123 More Information

Jose, Arun; Apewokin, Senu; Hussein, Walaa E; Ollberding, Nicholas J; Elwing, Jean M; Haslam, David B (2022. ) A unique gut microbiota signature in pulmonary arterial hypertension: A pilot study.Pulmonary circulation, , 12 (1 ) ,e12051 More Information

Paper Presentations

Arun Jose (2018. ) Abnormal Exercise pulmonary hemodynamics predict outcomes in patients with lung diseases .Nice, France. Conference. Level:International

Arun Jose (2017. ) The left and right ventricular end diastolic pressure ratio as a novel marker of disease severity in a cohort of patients with pulmonary arterial hypertension .Washington, DC. Conference. Level:International

Dr. Jose currently holds a 2nd Degree Black Belt in Shorinjiryu Kenyukai Watanabe-Ha Karatedo, achieved after years of study under 9th Degree Black Belt Shihan Watanabe Shunji, and remains an active practitioner of the art,