Patricia Joseph

Patricia M. Joseph , MD

Professor, Department of Internal Medicine, UC College of Medicine
Director, Adult Cystic Fibrosis

Medical Sciences Building
231 Albert Sabin Way, ML 0564
Cincinnati, Ohio 45267
Phone 513-558-4831
Fax 513-558-4858
Email patricia.joseph@uc.edu

Education

Bachelor's Degree: Texas A&M University 1972 (Zoology)

Master's Degree: Texas A&M University 1976 (Veterinary Anatomy)

Medical Degree: University of Tennessee 1984 (Medicine)

Internship : University of Tennessee 1985 (Internal Medicine )

Residency: University of Tennessee 1988 (Internal Medicine & Pediatrics)

Fellowship : Massachusetts General Hospital, Harvard Medical School 1992 (Pulmnoary & Critical Care Medicine )

Fellowship : Massachusetts General Hospital, Harvard Medical School 1988 (Pediatric Pulmonary )

Fellowship: University of Cincinnati/Children's Hospital Medical Center 2000 ( Pediatric Pulmonary )

Certifications

American Board of Internal Medicine (Critical Care Medicine) (Certification Date: 11-03-1993 ) - (Recertification Date: to 11-29-2010 )

American Board of Internal Medicine (Certification Date: 09-13-1989 )

American Board of Internal Medicine (Pulmonary Disease) (Certification Date: 11-04-1992 ) - (Recertification Date: to 11-29-2010 )

Clinical Interests

Critical Care Medicine

Pediatric Pulmonology

Pediatrics

Pulmonary Disease

Research and Practice Interests

Cystic Fibrosis, CF Related Bone Disease, Clinical Trials, Quality Improvement in Cystic Fibrosis.

Positions and Work Experience

1992 -1999 Instructor in Medicine, Harvard Medical School,

1999 -2004 Assistant Professor of Medicine, University of Cincinnati Medical Center, Cincinnati, OH

2004 -To Present Associate Professor of Medicine, University of Cincinnati Medical Center, Cincinnati, OH

Research Support

Investigators:D Borowitz, PM Joseph 09-11-2007 Altus Pharmaceuticals, Inc. An Open-Label Clinical Study Evaluating the Long-Term Safety of ALTU-135 for the Treatment of Patients with Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency Role:Site PI

Investigators:D Borowitz, PM Joseph 09-11-2007 Altus Pharmaceuticals, Inc. A Phase III, Randomized, Double-Blind, Placebo-Controlled Clinical Study Evaluating the Efficacy and Safety of ALTU-135 Treatmtent in Patients with Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency Role:Site PI

Investigators:S Moskowitz, PM Joseph 08-30-2006 Cystic Fibrosis Foundation Therapeutics Standard versus Biofilm Testing in Cystic Fibrosis Role:PI

Investigators:KF Almoosa, PM Joseph 03-30-2005 Midwest Consortium for Critical Care ICU-Aquired Paresis and the Risk for Mortality and Recurrent ICU Admissioin (Weakness and the ICU Readmission Evaluation - WIRE) Role:Sub-I

Investigators:KF Almoosa, PM Joseph 04-24-2005 Midwest Consortium for Critical Care A Multicenter Study of the Effect of Intensive Care Unit Attending Physician Work Schedules on Outcomes Relevant to Society Role:Sub-I

Grant: #412380050201 Investigators:Joseph, Patricia 08-01-2006 -05-31-2008 Cystic Fibrosis Foundation Standard versus Biofilm Susceptibility Testing in CF Role:PI $17,010.00 Closed Level:Private Non-Profit

Grant: #T164877 \ Sub Cystic Fibrosis Foundation Investigators:Joseph, Patricia 07-01-2013 -06-30-2014 Cystic Fibrosis Foundation TANGPR11A0 Vitamin D for Enhancing the Immune System in Cystic Fibrosis Role:PI $27,247.00 Active Level:Private Non-Profit

Grant: #JOSEPH15QI0 Investigators:Joseph, Patricia 01-01-2015 -12-31-2017 Cystic Fibrosis Foundation Transforming CF Care Through Shared Decision Making Role:PI $91,893.00 Active Level:Private Non-Profit

Grant: #CHMC_CFF Investigators:Indihar, Maria; Joseph, Patricia 07-01-2016 -12-31-2016 Cystic Fibrosis Foundation A CF C3N Care Model of the Future: Proposal for Piloting a Learning Health System Role:PI $15,000.00 Active Level:Private Non-Profit

Grant: #R1168_CFF GODFRE18QI0 Investigators:Joseph, Patricia 11-01-2018 -06-30-2019 Cystic Fibrosis Foundation Cystic Fibrosis Lung Transplant Transition Learning and Leadership Collaborative Role:PI $12,960.00 Awarded Level:Private Non-Profit

Grant: #R1226 / CCF GODFRE19QI0 Investigators:Joseph, Patricia 01-01-2019 -12-31-2019 Cystic Fibrosis Foundation Cystic Fibrosis Lung Transplant Regional Dissemination Network Role:PI $9,720.00 Awarded Level:Private Non-Profit

Grant: #JOSEPH15Y0 - CFF Therapeutics Development Center (TDC) Investigators:Indihar, Maria; Joseph, Patricia 04-01-2020 -03-31-2021 Cystic Fibrosis Foundation TDN - Cystic Fibrosis Foundatipn Therapeutics Development Center Role:Collaborator $45,770.40 Active Level:Private Non-Profit

Grant: #JOSEPH15Y4 Investigators:Indihar, Maria; Joseph, Patricia 04-01-2020 -03-31-2021 Cystic Fibrosis Foundation CFF ARC Grant Role:Collaborator $18,146.00 Active Level:Private Non-Profit

Publications

Peer Reviewed Publications

Moskowitz, Samuel M; Emerson, Julia C; McNamara, Sharon; Shell, Richard D; Orenstein, David M; Rosenbluth, Daniel; Katz, Marcia F; Ahrens, Richard; Hornick, Douglas; Joseph, Patricia M; Gibson, Ronald L; Aitken, Moira L; Benton, Wade W; Burns, Jane L (2011. ) Randomized trial of biofilm testing to select antibiotics for cystic fibrosis airway infection.Pediatric pulmonology, , 46 (2 ) ,184-92 More Information

Thomas, Heather; Risma, Kimberly A; Graham, T Brent; Brody, Alan S; Deutsch, Gail H; Young, Lisa R; Joseph, Patricia M (2007. ) A kindred of children with interstitial lung disease.Chest, , 132 (1 ) ,221-30 More Information

Robertson, Michael B; Choe, Kyuran A; Joseph, Patricia M Review of the abdominal manifestations of cystic fibrosis in the adult patient.Radiographics : a review publication of the Radiological Society of North America, Inc, , 26 (3 ) ,679-90 More Information

Aris, Robert M; Merkel, Peter A; Bachrach, Laura K; Borowitz, Drucy S; Boyle, Micheal P; Elkin, Sarah L; Guise, Theresa A; Hardin, Dana S; Haworth, Charles S; Holick, Michael F; Joseph, Patricia M; O'Brien, Kimberly; Tullis, Elizabeth; Watts, Nelson B; White, Terry B (2005. ) Guide to bone health and disease in cystic fibrosis.The Journal of clinical endocrinology and metabolism, , 90 (3 ) ,1888-96 More Information

Grossoehme, Daniel H; Ragsdale, Judith R; Cotton, Sian; Meyers, Melenie A; Clancy, John P; Seid, Michael; Joseph, Patricia M (2012. ) Using spirituality after an adult CF diagnosis: cognitive reframing and adherence motivation.Journal of health care chaplaincy, , 18 (3-4 ) ,110-20 More Information

Kong, Fansheng; Young, Lisa; Chen, Yi; Ran, Huimin; Meyers, Melanie; Joseph, Patricia; Cho, You-Hee; Hassett, Daniel J; Lau, Gee W (2006. ) Pseudomonas aeruginosa pyocyanin inactivates lung epithelial vacuolar ATPase-dependent cystic fibrosis transmembrane conductance regulator expression and localization.Cellular microbiology, , 8 (7 ) ,1121-33 More Information

Lee, Moon Jeong; Alvarez, Jessica A; Smith, Ellen M; Killilea, David W; Chmiel, James F; Joseph, Patricia M; Grossmann, Ruth E; Gaggar, Amit; Ziegler, Thomas R; Tangpricha, Vin (2015. ) Changes in Mineral Micronutrient Status During and After Pulmonary Exacerbation in Adults With Cystic Fibrosis.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, , 30 (6 ) ,838-43 More Information

Tangpricha, Vin; Smith, Ellen M; Binongo, Jose; Judd, Suzanne E; Ziegler, Thomas R; Walker, Seth; Tirouvanziam, Rabindra; Zughaier, Susu M; Lee, Moon Jeong; Chesdachai, Supavit; Hermes, Wendy A; Chmiel, James F; Gaggar, Amit; Grossmann, Ruth E; Joseph, Patricia M; Alvarez, Jessica A (2017. ) The Vitamin D for Enhancing the Immune System in Cystic Fibrosis (DISC) trial: Rationale and design of a multi-center, double-blind, placebo-controlled trial of high dose bolus administration of vitamin D3 during acute pulmonary exacerbation of cystic fibrosis.Contemporary clinical trials communications, , 6 ,39-45 More Information

Tangpricha, Vin; Lukemire, Joshua; Chen, Yuqing; Binongo, José Nilo G; Judd, Suzanne E; Michalski, Ellen S; Lee, Moon J; Walker, Seth; Ziegler, Thomas R; Tirouvanziam, Rabin; Zughaier, Susu M; Chesdachai, Supavit; Hermes, Wendy A; Chmiel, James F; Grossmann, Ruth E; Gaggar, Amit; Joseph, Patricia M; Alvarez, Jessica A (2019. ) Vitamin D for the Immune System in Cystic Fibrosis (DISC): a double-blind, multicenter, randomized, placebo-controlled clinical trial.The American journal of clinical nutrition, , 109 (3 ) ,544-553 More Information

Eckman, Mark H; Kopras, Elizabeth J; Montag-Leifling, Karen; Kirby, Lari P; Burns, Lisa; Indihar, Veronica M; Joseph, Patricia M Shared Decision-Making Tool for Self-Management of Home Therapies for Patients With Cystic Fibrosis.MDM policy & practice, , 2 (1 ) ,2381468317715621 More Information

Honors and Awards

1992 -1994 Shriners Burns Institute Research Fellowship

2003 -2004 Learning and Leadership Collaborative, Cystic Fibrosis Foundation

2004 -2006 Strathmore's Who's Who

2008 Cincinnati Magazine, Top Physicians in Pulmonary Medicine

Keywords

clinical studies, cystic fibrosis, bone disease, quality improvement

Contact Information

Academic - Medical Sciences Building
231 Albert Sabin Way, ML 0564
Cincinnati  Ohio, 45267
Phone: 513-558-4831
Fax: 513-558-4858
patricia.joseph@uc.edu

Practice - MAB
222 Piedmont Ave, Suite 4000
Cincinnati  Ohio, 45219
Phone: 513-475-8523
patricia.joseph@uc.edu