Golam Iftakhar Khandakar
Post Doc Fellow
Vontz Center for Molecular Studies, 3125 Eden Avenue
Cincinnati, Ohio 45267-0521
Email khandagi@ucmail.uc.edu
Education
Ph.D.: Kindai University Japan, 2023 (Pharmaceutical Sciences)
Positions and Work Experience
05-2022 -09-2022 Trainee, Completed a project “A spatiotemporal analysis of ERK phosphorylation mediated by GT-7” in the Laboratory of Nuclear Transport Dynamics , Center for Drug Design Research, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, JAPAN
10-2019 -03-2023 PhD Student, Kindai University, Higashiosaka, Osaka, Japan
01-2019 -09-2019 Brand manager, Worked in "Strategic Marketing Department", Radiant Pharmaceuticals Limited, Dhaka, Bangladesh
03-2017 -12-2018 Brand Executive, Worked in "Strategic Marketing Department", Radiant Pharmaceuticals Limited, Dhaka, Bangladesh
10-2015 -03-2017 Product Executive, Worked in "Product Management Department", General Pharmaceuticals Limited, Dhaka, Bangladesh
Publications
Peer Reviewed Publications
Golam Iftakhar Khandakar , Yoichi Miyamoto, Ryosuke Satoh, Kenta Kishimoto, Mingzuo Xie, Mengyu Shih, Teruaki Takasaki , Genzoh Tanabe , Masahiro Oka, Reiko Sugiura (2023. ) ACAGT-007a, an anti-cancer compound that modulates ERKMAPK signaling, induces nuclear enrichment ofphosphorylated ERK in T3M4 pancreatic cancer cells.Genes to Cells, , 28 (6 ) , 457-465 More Information
Golam Iftakhar Khandakar , Ryosuke Satoh , Teruaki Takasaki , Kana Fujitani , Genzoh Tanabe , Kazuko Sakai , Kazuto Nishio , Reiko Sugiura (2022. ) ACAGT-007a, an ERK MAPK Signaling Modulator, in Combination with AKT Signaling Inhibition Induces Apoptosis in KRAS Mutant Pancreatic Cancer T3M4 and MIA-Pa-Ca-2 Cells.Cells, , 11 (4 ) ,702 More Information
Teruaki Takasaki, Reo Obana, Daiki Fujiwara, Naofumi Tomimoto, Golam Iftakhar Khandakar, Ryosuke Satoh, and Reiko Sugiura (2023. ) ACA-28, an anticancer compound, induces Pap1 nuclear accumulation via ROS-dependent and -independent mechanisms in fission yeast. microPublication Biology, , More Information
Teruaki Takasaki ,Yasuyuki Hamabe , Kenta Touchi , Golam Iftakhar Khandakar , Takeshi Ueda , Hitoshi Okada, Kazuko Sakai, Kazuto Nishio, Genzoh Tanabe and Reiko Sugiura (2024. ) ACA-28, an ERK MAPK Signaling Modulator, Exerts Anticancer Activity through ROS Induction in Melanoma and Pancreatic Cancer Cells.Oxidative Medicine and Cellular Longevity, , 2024 , More Information
Presentations
Invited Presentations
Golam Iftakhar Khandakar , Ryosuke Satoh , Teruaki Takasaki , Kana Fujitani , Genzoh Tanabe , Reiko Sugiura (11-2021. ) Combination of ACAGT-007a, a novel ERK signaling modulator, with AKT signaling inhibitor effectively induces apoptosis in pancreatic cancer cells .140th Japanese Pharmacological Society, Nara Convention Center, Nara, Japan. Conference. . Level:National
Golam Iftakhar Khandakar , Ayami Mizuno, Ryosuke Satoh, Teruaki Takasaki , Genzoh Tanabe, Reiko Sugiura (12-2020. ) Impacts of ACA-28 derivatives on the ERK MAPK & PI3K/AKT signaling pathways in pancreatic cancer cells .Sysmex Hall and Shinryoku Hall, Kobe University, Graduate School of Medicine, Japan, Kobe University , Kobe, Japan. Other Institution. . Level:International
Poster Presentations
Golam Iftakhar Khandakar , Ryosuke Satoh , Shih Mengyu, Teruaki Takasaki , Kana Fujitani , Genzoh Tanabe , Kazuko Sakai , Kazuto Nishio ,Yoichi, Miyamoto, Masahiro Oka, Reiko Sugiura (12-13-2022. ) ACAGT-007a, A NEW ERK MAPK SIGNALING MODULATOR, WHEN COMBINED WITH AKT SIGNALING INHIBITOR, INHIBITS CELL GROWTH AND TRIGGERS APOPTOSIS IN PANCREATIC CANCER CELLS .Omni Rancho Las Palmas, Palm Spring, California. . Conference. . Level:International
Golam Iftakhar Khandakar , Ryosuke Satoh , Teruaki Takasaki , Kana Fujitani , Genzoh Tanabe , Kazuko Sakai , Kazuto Nishio , Reiko Sugiura (12-2021. ) ACAGT-007a, an ERK MAPK Signaling Modulator, when combined with AKT Signaling Inhibitor, Promotes Antitumor Activity in Pancreatic Cancer Cells .The 44th Annual Meeting of the Molecular Biology Society of Japan, Pacifico Yokohama, Japan. . Level:National
Golam Iftakhar Khandakar , Ayami Mizuno, Ryosuke Satoh, Teruaki Takasaki , Genzoh Tanabe, Reiko Sugiura (12-2020. ) Impacts of ACA-28 derivatives on the ERK MAPK & PI3K/AKT signaling pathways in pancreatic cancer cells .The 14th International conference on protein phosphatase, Kobe University , Kobe, Japan. . Level:International
Honors and Awards
10-2019 -03-2023 MEXT Scholarship Ministry of Education, Culture, Sports, Science and Technology Status:Recipient Level:University Type:Fellowship
Professional Affiliation
07-2021 -03-2023: Member The Molecular Biology Society of Japan (MBSJ), Tokyo, Japan
08-2021 -To Present: General Member The Japanese Pharmacological Society, Tokyo, Japan
07-2022 -To Present: Member The Japanese Association of Protein Phosphatases (JAPPR), Sapporo, Japan
10-2023 -To Present: Associate Member American Association for Cancer Research (AACR), 615 Chestnut St, Philadelphia, PA 19106, USA
10-2023 -To Present: Fellow Member International Association for the Study of Lung Cancer (IASLC), Denver, Colorado 80202-2725, USA
10-2023 -To Present: Member Society for Immunotherapy of Cancer (SITC), Milwaukee, WI
Contact Information
Academic - Vontz Center for Molecular Studies, 3125 Eden Avenue
Cincinnati
Ohio, 45267-0521
khandagi@ucmail.uc.edu