Harshita Kumari

Harshita Kumari

Associate Professor

Medical Sciences Building

3109 C

Pharmacy Kumari Lab - 0004

Kumari's Lab
231 Albert Sabin Way
Cincinnati, Ohio 45229

Professional Summary

Harshita Kumari is an Associate Professor in the Division of Pharmaceutical Sciences at the University of Cincinnati. Dr. Kumari’s work in the area of solution chemistry of supramolecular complexes is widely recognized. Her current research focuses on integrating principles of modern biophysics into material and formulation science towards the development of novel skin care, oral care, and hair care products. Her research projects focus on understanding mechanisms of delivery and deposition of actives onto the skin/hair and elucidating the parameters to control them. In addition, her research focuses on developing methods to construct novel nanometric delivery vehicles, based on the principles of self-assembly and molecular recognition. Her work is published in several peer-reviewed journals. 

Education

PhD, University of Missouri Columbia, MO, USA, 2011 (Supramolecular Chemistry)

B.Tech., Nagpur University 2005 (Cosmetic Science)

Positions and Work Experience

2005 -2006 Research Executive, Global Technology Center-Oral Care Division, Unilever, India

Research and Practice Interests

For research details go to: www.kumarilab.com

Research Support

Grant: #013073 Exhibit A Investigators:Kumari, Harshita 11-01-2020 -10-31-2021 Procter & Gamble Company Investigating the Composition, Morphology and Kinetics of Varying Aluminium Salt Chemistries Involved in Ductal and Skin Surface Eccrine Sweat Management Role:PI $220,000.00 Awarded Level:Industry

Publications

Peer Reviewed Publications

Patil, Rahul S.; Kumari, Harshita; Barnes, Charles L.; Atwood, Jerry L. (2015. ) Engineering supramolecular organic frameworks (SOFs) of C-alkylpyrogallol[4]arene with bipyridine-based spacers .Chem. Commun. (Cambridge, U. K.), , 51 (12 ) ,2304-2307

Patil, Rahul S.; Drachnik, Amanda M.; Kumari, Harshita; Barnes, Charles L.; Deakyne, Carol A.; Atwood, Jerry L. (2015. ) Solvent induced manipulation of Supramolecular Organic Frameworks .Cryst. Growth Des., , 51 (21 ) ,Ahead of Print

Kumari, Harshita; Jin, Ping; Teat, Simon J.; Barnes, Charles L.; Dalgarno, Scott J.; Atwood, Jerry L. (2014. ) Strong Cation···Ï? Interactions Promote the Capture of Metal Ions within Metal-Seamed Nanocapsule .J. Am. Chem. Soc., , 136 (49 ) ,17002-17005

Jin, Ping; Kumari, Harshita; Kennedy, Stuart; Barnes, Charles L.; Teat, Simon J.; Dalgarno, Scott J.; Atwood, Jerry L. (2014. ) Structural alteration of the metal-organic pyrogallol[4]arene nano-capsule motif by incorporation of large metal centres .Chem. Commun. (Cambridge, U. K.), , 50 (34 ) ,4508-4510

Kumari, Harshita; Mossine, Andrew V.; Schuster, Nathaniel J.; Barnes, Charles L.; Deakyne, Carol A.; Atwood, Jerry L. (2014. ) Packing arrangements of copper-seamed C-alkylpyrogallol[4]arene nanocapsules with varying chain lengths .CrystEngComm, , 16 (18 ) ,3718-3721

Mayhan, Collin M.; Kumari, Harshita; McClure, Elizabeth M.; Liebman, Joel F.; Deakyne, Carol A. (2014. ) Proton affinity and gas-phase basicity of hydroxyquinol: A computational study .J. Chem. Thermodyn., , 73 (18 ) ,171-177

Kumari, Harshita; Deakyne, Carol A.; Atwood, Jerry L. (2014. ) Solution Structures of Nanoassemblies Based on Pyrogallol[4]arenes .Acc. Chem. Res., , 47 (10 ) ,3080-3088

Kumari, Harshita; Kline, Steven R.; Fowler, Drew A.; Mossine, Andrew V.; Deakyne, Carol A.; Atwood, Jerry L. (2014. ) Solution superstructures: truncated cubeoctahedron structures of pyrogallol[4]arene nanoassemblies .Chem. Commun. (Cambridge, U. K.), , 50 (1 ) ,109-111

Patil, Rahul S.; Mossine, Andrew V.; Kumari, Harshita; Barnes, Charles L.; Atwood, Jerry L. (2014. ) Engineering Void Space Enclosed within Resorcin[4]arene-Based Supramolecular Frameworks .Cryst. Growth Des., , 14 (10 ) ,5212-5218

Kumari, Harshita; Jin, Ping; Teat, Simon J.; Barnes, Charles L.; Dalgarno, Scott J.; Atwood, Jerry L. (2014. ) Entrapment of Elusive Guests within Metal-Seamed Nanocapsules .Angew. Chem., Int. Ed., , 53 (48 ) ,13088-13092

Drachnik, Amanda M.; Kumari, Harshita; Barnes, Charles L.; Deakyne, Carol A.; Atwood, Jerry L. (2014. ) Encapsulation of manganese and cobalt complexes within resorcin[4]arene dimers .CrystEngComm, , 16 (31 ) ,7172-7175

Fowler, Drew A.; Rathnayake, Asanka S.; Kennedy, Stuart; Kumari, Harshita; Beavers, Christine M.; Teat, Simon J.; Atwood, Jerry L. (2013. ) Introducing Defects into Metal-Seamed Nanocapsules Using Mixed Macrocycles .J. Am. Chem. Soc., , 135 (33 ) ,12184-12187

Kumari, Harshita; Dennis, Cindi L.; Mossine, Andrew V.; Deakyne, Carol A.; Atwood, Jerry L. (2013. ) Magnetic Differentiation of Pyrogallol[4]arene Tubular and Capsular Frameworks .J. Am. Chem. Soc., , 135 (19 ) ,7110-7113

Kumari, Harshita; Jin, Ping; Deakyne, Carol A.; Atwood, Jerry L. (2013. ) Metal Ion Transport Across Metal-organic Pyrogallol[4]arene-based Nanocapsules .Curr. Org. Chem., , 17 (14 ) ,1481-1488

Kumari, Harshita; Good, Allison J.; Smith, Vincent J.; Barbour, Leonard J.; Deakyne, Carol A.; Atwood, Jerry L. (2013. ) 18-Crown-6 templates offset-linked pyrogallol[4]arene dimers .Supramol. Chem., , 25 (9-11 ) ,591-595

Kumari, Harshita; Zhang, Jin; Erra, Loredana; Barbour, Leonard J.; Deakyne, Carol A.; Atwood, Jerry L. (2013. ) Cocrystals of gabapentin with C-alkylresorcin[4]arenes .CrystEngComm, , 15 (20 ) ,4045-4048

Kumari, Harshita; Erra, Loredana; Webb, Alicia C.; Bhatt, Prashant; Barnes, Charles L.; Deakyne, Carol A.; Adams, John E.; Barbour, Leonard J.; Atwood, Jerry L. (2013. ) Pyrogallol[4]arenes as Frustrated Organic Solids .J. Am. Chem. Soc., , 135 (45 ) ,16963-16967

Kumari, Harshita; Kline, Steven R.; Dennis, Cindi L.; Mossine, Andrew V.; Paul, Rick L.; Deakyne, Carol A.; Atwood, Jerry L. (2012. ) Solution-Phase and Magnetic Approach towards Understanding Iron Gall Ink-like Nanoassemblies .Angew. Chem., Int. Ed., , 51 (37 ) ,9263-9266, S9263/1-S9263/17

Kumari, Harshita; Kline, Steven R.; Dennis, Cindi L.; Mossine, Andrew V.; Paul, Rick L.; Deakyne, Carol A.; Atwood, Jerry L. (2012. ) Solution-phase and magnetic approach towards understanding iron gall ink-like nanoassemblies .Angew Chem Int Ed Engl, , 51 (37 ) ,9263-6

Kumari, Harshita; Kline, Steven R.; Wycoff, Wei G.; Paul, Rick L.; Mossine, Andrew V.; Deakyne, Carol A.; Atwood, Jerry L. (2012. ) Solution-phase Structures of Gallium-containing Pyrogallol[4]arene Scaffolds .Angew. Chem., Int. Ed., , 51 (21 ) ,5086-5091, S5086/1-S5086/31

Kumari, Harshita; Kline, Steven R.; Wycoff, Wei G.; Paul, Rick L.; Mossine, Andrew V.; Deakyne, Carol A.; Atwood, Jerry L. (2012. ) Solution-phase structures of gallium-containing pyrogallol[4]arene scaffolds .Angew Chem Int Ed Engl, , 51 (21 ) ,5086-91

Kumari, Harshita; Mossine, Andrew V.; Kline, Steven R.; Dennis, Cindi L.; Fowler, Drew A.; Teat, Simon J.; Barnes, Charles L.; Deakyne, Carol A.; Atwood, Jerry L. (2012. ) Controlling the Self-Assembly of Metal-Seamed Organic Nanocapsules .Angew. Chem., Int. Ed., , 51 (6 ) ,1452-1454, S1452/1-S1452/203

Kumari, Harshita; Mossine, Andrew V.; Kline, Steven R.; Dennis, Cindi L.; Fowler, Drew A.; Teat, Simon J.; Barnes, Charles L.; Deakyne, Carol A.; Atwood, Jerry L. (2012. ) Controlling the self-assembly of metal-seamed organic nanocapsules .Angew Chem Int Ed Engl, , 51 (6 ) ,1452-4

Kumari, Harshita; Kline, Steven R.; Wycoff, Wei G.; Atwood, Jerry L. (2012. ) Investigating Structural Alterations in Pyrogallol[4]arene-Pyrene Nanotubular Frameworks .Small, , 8 (21 ) ,3321-3325

Kumari, Harshita; Kline, Steven R.; Atwood, Jerry L. (2012. ) Investigation of encapsulation of insulin biotemplate within C-methylresorcin[4]arenes .Chem. Commun. (Cambridge, U. K.), , 48 (30 ) ,3599-3601

Mossine, Andrew V.; Kumari, Harshita; Fowler, Drew A.; Shih, Annie; Kline, Steven R.; Barnes, Charles L.; Atwood, Jerry L. (2012. ) Ferrocene Species Included within a Pyrogallol[4]arene Tube .Chem. - Eur. J., , 18 (33 ) ,10258-10260, S10258/1-S10258/114

Kumari, Harshita; Dennis, Cindi L.; Mossine, Andrew V.; Deakyne, Carol A.; Atwood, Jerry L. (2012. ) Exploring the Magnetic Behavior of Nickel-Coordinated Pyrogallol[4]arene Nanocapsules .ACS Nano, , 6 (1 ) ,272-275

Mossine, Andrew V.; Kumari, Harshita; Fowler, Drew A.; Maerz, Andrew K.; Kline, Steven R.; Barnes, Charles L.; Atwood, Jerry L. (2011. ) Ferrocene as a Hydrophobic Templating Agent with Pyrogallol[4]arenes .Isr. J. Chem., , 51 (7 ) ,840-842

Kumari, Harshita; Kline, Steven R.; Schuster, Nathaniel J.; Barnes, Charles L.; Atwood, Jerry L. (2011. ) Exploring the Ellipsoidal and Core-Shell Geometries of Copper-Seamed C-Alkylpyrogallol[4]arene Nanocapsules in Solution .J. Am. Chem. Soc., , 133 (45 ) ,18102-18105

Kumari, Harshita; Kline, Steven R.; Schuster, Nathaniel J.; Atwood, Jerry L. (2011. ) Solution structure of copper-seamed C-alkylpyrogallol[4]arene nanocapsules with varying chain lengths .Chem. Commun. (Cambridge, U. K.), , 47 (45 ) ,12298-12300

Maerz, Andrew K.; Fowler, Drew A.; Mossine, Andrew V.; Mistry, Miten; Kumari, Harshita; Barnes, Charles L.; Deakyne, Carol A.; Atwood, Jerry L. (2011. ) Solvent mediated self-assembly of organic nanostructures .New J. Chem., , 35 (4 ) ,784-787

Kumari, Harshita; Kline, Steven R.; Kennedy, Stuart R.; Garvey, Christopher; Raston, Colin L.; Atwood, Jerry L.; Steed, Jonathan W. (2016. ) Manipulating three-​dimensional gel network entanglement by thin film shearing .Chem. Commun., , 52, ,4513

Kumari, Harshita; Armitage, Sarah E.; Kline, Steven R.; Damodaran, Krishna K.; Kennedy, Stuart R.; Atwood, Jerry L.; Steed, Jonathan W. (2015. ) Fluorous 'ponytails' lead to strong gelators showing thermally induced structure evolution .Soft Matter, , 11 (43 ) ,8471-8478

Vimalanathan, K.; Gascooke, J. R.; Suarez-Martinez, I.; Marks, N. A.; Kumari, H.; Garvey, C. J.; Atwood, J. L.; Lawrance, W. D.; Raston, C. L. (2016. ) Fluid dynamic lateral slicing of high tensile strength carbon nanotubes .Scientific Reports (Nature Publishing), , 6, ,22865

Patil, Rahul S.; Kumari, Harshita; Barnes, Charles L.; Atwood, Jerry L. (2015. ) Anion- and Spacer-​Directed Host-​Guest Complexes of Bipyridine with Pyrogallol[4]​arene .Chem. - Eur. J., , 21 (29 ) ,10431-10435

Kumari, Harshita; Barnes, Charles L.; Deakyne, Carol A.; Atwood, Jerry L. (2016. ) Metal exchange study of pyrogallol[4]arene based nanocapsules .CrystEngComm, , 18 (26 ) ,4909–4913

Mayhan, Collin M.; Drachnik, Amanda M.; Mossine, Andrew V.; Kumari, Harshita; Adams,John E.; Atwood, Jerry L.; Deakyne, Carol A. (2016. ) Metal organic nanocapsules as two-dimensional network building blocks .J. Phys. Chem.-C, , 120 (24 ) ,13159-13168

Dawn, Arnab; Chandra, Harish; Ade-Browne, Chandra; Yadav, Jagjit; Kumari, Harshita (2017. ) Multifaceted Supramolecular Interactions from C-methylresorcin[4]arene Lead to an Enhancement in In Vitro Antibacterial Activity of Gatifloxacin. Chemistry (Weinheim an der Bergstrasse, Germany), , 23 (72 ) ,18171-18179

Drachnik, Amanda M; Kumari, Harshita; Mayhan, Collin M; Fowler, Drew A; Wycoff, Wei G; Barnes, Charles L; Adams, John E; Deakyne, Carol A; Atwood, Jerry L (2017. ) Conversion of Pregabalin to 4-Isobutylpyrrolidone-2. Journal of pharmaceutical sciences, , 106 (10 ) ,3095-3102

Dawn, Arnab; Kumari, Harshita (2018. ) Low Molecular Weight Supramolecular Gels Under Shear: Rheology as the Tool for Elucidating Structure-Function Correlation. Chemistry (Weinheim an der Bergstrasse, Germany), , 24 ,762-776

Kumari, Harshita; Kline, Steven R; Kennedy, Stuart R; Garvey, Christopher; Raston, Colin L; Atwood, Jerry L; Steed, Jonathan W (2016. ) Manipulating three-dimensional gel network entanglement by thin film shearing.Chemical communications (Cambridge, England), , 52 (24 ) ,4513-6

Vimalanathan, Kasturi; Gascooke, Jason R; Suarez-Martinez, Irene; Marks, Nigel A; Kumari, Harshita; Garvey, Christopher J; Atwood, Jerry L; Lawrance, Warren D; Raston, Colin L (2016. ) Fluid dynamic lateral slicing of high tensile strength carbon nanotubes.Scientific reports, , 6 ,22865

Kumari, Harshita; Armitage, Sarah E; Kline, Steven R; Damodaran, Krishna K; Kennedy, Stuart R; Atwood, Jerry L; Steed, Jonathan W (2015. ) Fluorous 'ponytails' lead to strong gelators showing thermally induced structure evolution.Soft matter, , 11 (43 ) ,8471-8

Patil, Rahul S; Kumari, Harshita; Barnes, Charles L; Atwood, Jerry L (2015. ) Anion- and Spacer-Directed Host-Guest Complexes of Bipyridine with Pyrogallol[4]arene.Chemistry (Weinheim an der Bergstrasse, Germany), , 21 (29 ) ,10431-5

Ade-Browne, C.; Mirzamani, M.; Dawn, A.; Qian, S; Thompson, R.; Glenn, R; Kumari, H. (2020. ) Effect of ethoxylation and lauryl alcohol on the self-assembly of sodium laurylsulfate: Significant structural and rheological transformation.Colloids and Surfaces: A physiochemical and engineering aspect, , 595 ,425-431

Dawn, Arnab; Yao, Xue; Yu, Ying; Jiang, Jianxiong; Kumari, Harshita (2019. ) Assessment of the in vitro toxicity of calixarenes and a metal-seamed calixarene: a chemical pathway for clinical application.Supramolecular chemistry, , 31 (7 ) ,425-431

Dawn, Arnab; Mirzamani, Marzieh; Jones, Christopher D; Yufit, Dmitry S; Qian, Shuo; Steed, Jonathan W; Kumari, Harshita (2018. ) Investigating the effect of supramolecular gel phase crystallization on gel nucleation.Soft matter, , 14 (46 ) ,9489-9497

Dawn, Arnab; Eisenhart, Andrew; Mirzamani, Marzieh; Beck, Thomas L; Kumari, Harshita (2018. ) Bowl-in-bowl complex formation with mixed sized calixarenes: adaptivity towards guest binding.Chemical communications (Cambridge, England), , 54 (52 ) ,7131-7134

Ade-Browne, C.; Dawn, A.; Mirzamani, M.; Qian, S; Kumari, H. (2019. ) Differential Behaviors of Sodium laurylsulfate Micelles in the Presence of Nonionic Polymers . J. Colloid & Interface Sci., , 544 ,276-283

Kumari, H.; Eisenhart, A.; Pajoubpong, J.; Heinrich, F.; Beck, T. (2020. ) Investigating partitioning of free versus macrocycle bound guest into a model POPC lipid bilayer .RSC Advances, , 10 (26 ) ,15148-15153

He, S.; Joseph, N.; Mirzamani, M.; Pye, S. J.; Mohammed Al-anataki, A. H.; Whitten, A. E.; Chen, Y., Kumari, H.; Raston, C.L. (2020. ) Vortex fluidic mediated encapsulation of functional fish oil featuring in situ probed small angle neutron scattering.Nature Science of Food, , 40 (12 ) ,

Honors and Awards

2012 Journals Grants for International Authors by Royal Society of Chemistry Status:Recipient Level:International

2005 Gold Medalist, Department of Cosmetic Science, Nagpur University Status:Recipient Level:National

2012 Young Scientist Award for Indaba 7 conference on Insights from Structures, Skukuza in the Kruger National Park, South Africa

Post Graduate Training and Education

2011-2013 Postdoctoral Fellow, University of Missouri, , Columbia, MO, USA

2013-2014 Research Associate, University of Missouri, , Columbia, MO, USA

Keywords

supramolecular chemistry, neutron scattering, cosmetic science, formulation, materials, solid-state chemistry

Contact Information

Research - Kumari's Lab
231 Albert Sabin Way
Cincinnati  Ohio, 45229
http://kumarilab.com