Alex Lentsch

Alex B Lentsch

Senior Associate Dean for Faculty Affairs & Development, and Professor and Vice Chair for Research in Surgery

Care/Crawley

870

COM Dean Admin Operations - 0553

CARE/Crawley Building
Room E870
Cincinnati, Ohio 45267

Education

Bachelor's Degree, Northern Kentucky University 1991 (Biological Sciences)

Doctoral Degree, University of Louisville 1996 (Physiology and Biophysics)

Research and Practice Interests

Inflammation, Liver Injury, Trauma, Military Medicine

Research Support

Grant: #R01 DK56029 Investigators:Lentsch, AB 09-30-2000 -08-31-2009 NIH/NIDDK Regulation of hepatic ischemia/reperfusion injury Role:Principal Investigator Type:Grant

Grant: #R01 AG025881 Investigators:Lentsch, AB 06-01-2005 -05-31-2010 NIH/NIA Age effects on inflammation and injury Role:Principal Investigator Type:Grant

Grant: #R01 GM072760 Investigators:Caldwell, CC 09-01-2005 -08-31-2010 NIH/NIGMS Role of HIF-1alpha in T cells during sepsis Role:Co-Investigator Type:Grant

Grant: #R01 DK055030 Investigators:Schuschke, DA 07-01-2007 -03-31-2009 NIH/NIDDK Leukocyte adhesion in copper-deficient microcirculation Role:Co-Investigator Type:Grant

Grant: #T32 GM08478 Investigators:Solomkin, JS 07-01-2008 -06-30-2013 NIH/NIGMS Host response to trauma research training program Role:Co-Program Director Type:Grant

Grant: #K02-HL-072552 Investigators:Lentsch, Alex 07-01-2002 -06-30-2007 National Heart, Lung and Blood Institute Hepatic Ischemia/Reperfusion-Induced Lung Injury Role:PI $536,220.00 Closed Level:Federal

Grant: #R01-DK-56029 Investigators:Lentsch, Alex 09-30-2004 -08-31-2009 National Inst of Diabetes and Digestive and Kidney Disease Regulation of Hepatic Ischemia/Reperfusion Injury Role:PI $1,705,844.00 Closed Level:Federal

Grant: #5-R01-AG-025881-02-A0-S0-E0 Investigators:Lentsch, Alex 06-01-2005 -07-31-2010 National Institute on Aging Age Effects on Liver Inflammation and Injury Role:PI $1,468,415.00 Closed Level:Federal

Investigators:Lentsch, Alex 08-01-2002 -07-31-2005 Department of the Army Chemokines and Prostate Tumor Growth Role:PI $313,998.00 Closed Level:Federal

Grant: #5-R01-DK-56029-05-A0-S0-E0 Investigators:Lentsch, Alex 05-01-2002 -09-29-2004 National Inst of Diabetes and Digestive and Kidney Disease Regulation of Hepatic Ischemia/Reperfusion Injury Role:PI $454,608.00 Closed Level:Federal

Grant: #OGMB040896 / NIH 5R01D055030-07 Investigators:Lentsch, Alex 07-01-2007 -03-31-2009 National Inst of Diabetes and Digestive and Kidney Disease Leukocyte Adhesion in Copper Deficient Microcirculation Role:PI $55,067.00 Active Level:Federal

Grant: #2008 Agreements Investigators:Lentsch, Alex 01-01-2008 -12-31-2008 Shriners Hospitals for Children - Cincinnati Shriners - Surgery Consulting Requisitions 2008 Role:PI $992,919.60 Active Level:Private Non-Profit

Grant: #T32 GM008478 Investigators:Lentsch, Alex 07-01-2008 -06-30-2013 National Institute of General Medical Sciences Host Response to Trauma Research Training Program Role:PI $1,156,018.00 Active Level:Federal

Grant: #611-243-11SAM-00-104583 / FA8650-05-2-6518 Investigators:Barnes, Stephen; Dorlac, Warren; Lentsch, Alex 06-01-2008 -08-31-2010 Department of the Army Medical Research and Materiel Command Strategic Aeromedical Evacuation Effects On Very Severely Injured (VSI) Casualties Role:PI $1,479,650.00 Active Level:Federal

Grant: #R01 CA125379 Investigators:Collins, Margaret; Ho, Shuk Mei; Knudsen, Karen; Lentsch, Alex; Waltz, Susan 09-01-2008 -07-31-2014 National Cancer Institute The Ron Receptor/Chemokine Axis in Prostate Cancer Role:Collaborator $1,275,379.00 Active Level:Federal

Grant: #2009 Agreements Investigators:Lentsch, Alex 01-01-2009 -12-31-2009 Shriners Hospitals for Children - Cincinnati Shriners - Surgery Consulting Requisitions 2009 Role:PI $937,527.00 Closed Level:Private Non-Profit

Grant: #USAF-CRADA Investigators:Lentsch, Alex 04-07-2009 -04-06-2014 United States Air Force Academy Coopertive Research and Development Agreement: Cadet Summer Research Program Role:PI $.00 Active Level:Federal

Grant: #2 R01 DK056029-11A1 Investigators:Edwards, Michael; Lentsch, Alex 09-01-2009 -08-31-2014 National Inst of Diabetes and Digestive and Kidney Disease Chemokine Regulation of Liver Injury and Recovery Role:PI $1,742,158.00 Active Level:Federal

Grant: #FA7014-09-2-0006 Investigators:Athota, Krishna; Dorlac, Warren; Johannigman, Jay; Lentsch, Alex 09-30-2009 -09-29-2013 Department of the Air Force Effect of Omega-3 Fatty Acid Supplementation of Infection Rate and Morbidity in Multisystem Trauma Patients Role:Collaborator $654,960.00 Active Level:Federal

Grant: #FA7014-09-2-0005 (WOUND) Investigators:Dorlac, Warren; Johannigman, Jay; Lentsch, Alex; Pritts, Timothy 09-30-2009 -09-29-2011 Department of the Air Force Effect of Altitude on Wound Infection and Changes Seen After Treatment with Supplemental Oxygen and Negative Pressure Wound Therapy Role:PI $900,000.00 Active Level:Federal

Grant: #W81XWH-09-1-0625 Investigators:Caldwell, Charles; Lentsch, Alex 09-03-2009 -09-02-2012 Department of the Army Medical Research Acquisition Activity Effects of Different Fluid Resuscitation Strategies on Systemic Inflammation, Immunocompromise, Organ Dysfunction and Death Role:PI $708,840.00 Closed Level:Federal

Grant: #SRS 006688 Investigators:Lentsch, Alex 01-01-2010 -12-31-2010 Shriners Hospitals for Children - Cincinnati Shriners - Surgery Consulting Requisitions 2010 Role:PI $346,842.00 Closed Level:Private Non-Profit

Grant: #R01 AG025881 Investigators:Lentsch, Alex 08-01-2010 -05-31-2015 National Institute on Aging Age Effects on Liver Inflammation and Injury Role:PI $1,205,644.00 Active Level:Federal

Grant: #CSTARS Co-op Master Agreement Investigators:Lentsch, Alex 08-01-2010 -07-31-2015 Department of the Air Force Expeditionary Medicine, Trauma, and Enroute CARE (EMTEC) Research and Technology Support - Basic Agreement Role:PI $.00 Active Level:Federal

Grant: #SHRINERS 2011 Investigators:Lentsch, Alex 01-01-2011 -12-31-2011 Shriners Hospitals for Children - Cincinnati Shriners - Surgery Consulting Requisitions 2010 Role:PI $328,571.33 Closed Level:Private Non-Profit

Grant: #FA8650-10-2-6B01 Task 1 Investigators:Lentsch, Alex 08-11-2010 -08-10-2013 Air Force Research Laboratory Expeditionary Medicine, Trauma, and Enroute CARE (EMTEC) Research and Technology Support - Basic Agreement Role:PI $1,978,172.00 Active Level:Federal

Grant: #FA8650-11-2-6B05 Task 5 Investigators:Branson, Richard; Caldwell, Charles; Johannigman, Jay; Lentsch, Alex; Pritts, Timothy 11-23-2010 -11-22-2012 Air Force Research Laboratory Determining the Oxygen Requirements Using an Oxygen Concentrator at Altitude Role:Collaborator $776,561.00 Active Level:Federal

Grant: #Shriners 2012 Investigators:Lentsch, Alex 01-01-2012 -12-31-2012 Shriners Hospitals for Children - Cincinnati Shrine 2012 Surgery Role:PI $367,530.96 Active Level:Private Non-Profit

Grant: #FA8650-12-2-6B11 Task 11 Under Master FA8650-10-2-6140 Investigators:Branson, Richard; Dorlac, Warren; Hinckley, William; Johannigman, Jay; Lentsch, Alex; Lindsell, Christopher; McMullan, Jason; Meunier, Jason; Robinson, Bryce 05-08-2012 -05-07-2015 Department of the Air Force Closed Loop Control of Mechanical Ventilation, FA8650-12-2-6B11 Role:Collaborator $503,000.00 Active Level:Federal

Grant: #FA8650-12-2-6B10 Task order 10 Investigators:Branson, Richard; Dorlac, Warren; Johannigman, Jay; Lentsch, Alex; Robinson, Bryce 05-09-2012 -05-08-2015 Department of the Air Force Closed Loop Control of Oxygen Delivery and Oxygen Generation, FA8650-12-2-6B10 Role:Collaborator $674,000.00 Active Level:Federal

Grant: #2013 Consultant Requisition Investigators:Lentsch, Alex 01-01-2013 -12-31-2013 Shriners Hospitals for Children - Cincinnati Shriner's Hospital Consulting Agreements, calendar year 2013 Role:PI $347,840.54 Awarded Level:Private Non-Profit

Grant: #T32GM008478 Investigators:Lentsch, Alex 07-01-2013 -06-30-2018 National Institute of General Medical Sciences Host Response to Trauma Research Training Program Role:PI $181,925.00 Awarded Level:Federal

Grant: #132581 \ R21AA020846 Investigators:Lentsch, Alex 05-08-2013 -01-31-2014 National Institute on Alcohol Abuse and Alcoholism Mechanisms of Alcoholic Liver Disease Role:PI $31,777.00 Active Level:Federal

Grant: #R01 GM107625 Investigators:Caldwell, Charles; Lentsch, Alex; Pritts, Timothy 02-01-2014 -12-31-2018 National Institute of General Medical Sciences Red blood cell microparticles and lung inflammation after hemorrhage and resuscit Role:Collaborator $313,038.00 Awarded Level:Federal

Grant: #FA8650-14-2-6B20 under Master FA8650-10-2-6140 Investigators:Caldwell, Charles; Lentsch, Alex; Pritts, Timothy 05-23-2014 -05-22-2015 Air Force Research Laboratory Effect of pRBC Cryopreservation on Development of the Storage Lesion and Inflammation Role:Collaborator $247,143.00 Active Level:Federal

Grant: #FA8650-14-2-6B25 / Task under Master FA8650-10-2-6140 Investigators:Lentsch, Alex 06-18-2014 -06-17-2015 Air Force Research Laboratory Evaluation of Mouse Wound Models for Probiotic-Based Wound Infection Prevention Studies Role:PI $242,020.00 Awarded Level:Federal

Grant: #SHRINE 2014 Investigators:Lentsch, Alex 01-01-2014 -12-31-2014 Shriners Hospitals for Children - Cincinnati Shriner's Hospital Consulting Agreements, calendar year 2014 Role:PI $350,968.00 Awarded Level:Private Non-Profit

Grant: #FA8650-14-2-6B33 (Task 33 under Master FA8650-10-2-6140) Investigators:Lentsch, Alex; Robinson, Bryce 09-11-2014 -09-10-2015 Air Force Research Laboratory Reducing biofilm and ventilator associated pneumonia using sphingosine Role:Collaborator $252,210.00 Awarded Level:Federal

Grant: #R01 DK056029 Investigators:Lentsch, Alex 07-01-2015 -06-30-2019 National Inst of Diabetes and Digestive and Kidney Disease Chemokine/exosome axis and liver repair after ischemia/reperfusion Role:PI $430,057.00 Awarded Level:Federal

Grant: #SHRINE 2015 Investigators:Lentsch, Alex 01-01-2015 -12-31-2015 Shriners Hospitals for Children - Cincinnati Shriner's Hospital Consulting Agreements, calendar year 2015 Role:PI $400,179.00 Active Level:Private Non-Profit

Grant: #FA8650-15-2-6B35 / Task under Master FA8650-10-2-6140 Investigators:Athota, Krishna; Lentsch, Alex; Makley, Amy; Pritts, Timothy 07-15-2015 -01-14-2017 Air Force Research Laboratory Comparison of Combat Gauze with Fibrin Sealant Patch in Hemorrhage Control after Vascular or Hepatic Trauma Role:Collaborator $231,000.00 Awarded Level:Federal

Grant: #CSTARS Co-op EMTEC Master Agreement Investigators:Lentsch, Alex 09-29-2015 -09-28-2021 Air Force Research Laboratory Expeditionary Medicine, Trauma, and Enroute Care (EMTEC) Research and Technology Development Co-op Agreement Role:PI $.00 Active Level:Federal

Grant: #2016 Shriner's Investigators:Lentsch, Alex 01-01-2016 -12-31-2016 Shriners Hospitals for Children - Cincinnati Shriner's Hospital Consulting Agreements, calendar year 2016 Role:PI $468,237.20 Awarded Level:Private Non-Profit

Grant: #FA8650-16-2-6G05 (Task under Master FA8650-15-2-6605) Investigators:Caldwell, Charles; Goodman, Michael; Lentsch, Alex; Makley, Amy; Pritts, Timothy; Robinson, Bryce 02-26-2016 -02-25-2019 Air Force Research Laboratory Effect of fluid resuscitation strategy during en route care on acute lung injury after hemorrhage and burn injury. Role:Collaborator $396,000.00 Awarded Level:Federal

Grant: #135658 / W81XWH-15-1-0370 Investigators:Lentsch, Alex; Wang, Jiang 09-30-2015 -09-29-2018 Department of the Army Medical Research Acquisition Activity Mechanisms of nonalcoholic steatohepatitis Role:Collaborator $3,600.00 Awarded Level:Federal

Grant: #DoD1-SA1 / W81XWH-15-2-0065 Investigators:Babcock, George; Lentsch, Alex 01-01-2017 -12-31-2017 Department of the Army Medical Research Acquisition Activity Antimicrobial block copolypeptides (A-Blocks): Innovative Therapeutics and Prophylacics for Wound Infection Role:Collaborator $517,802.00 Awarded Level:Federal

Grant: #Shriner's 2017 Investigators:Lentsch, Alex 01-01-2017 -12-31-2017 Shriners Hospitals for Children - Cincinnati Shriner's Hospital Consulting Agreements, calendar year 2017 Role:PI $766,576.00 Awarded Level:Private Non-Profit

Grant: #FA8650-17-2-6G23 (Task under Master FA8650-15-2-6605) Investigators:Edwards, Michael; Gulbins, Erich; Johannigman, Jay; Lentsch, Alex 03-30-2017 -03-29-2019 Air Force Research Laboratory Role of Sphingosine Coated Endotracheal Tubes (ETT) in Preventing Endotracheal Biofilm Role:Collaborator $231,000.00 Awarded Level:Federal

Grant: #Shriner's 2018 Investigators:Lentsch, Alex 01-01-2018 -12-31-2018 Shriners Hospitals for Children - Cincinnati Shriner's Hospital Consulting Agreements, calendar year 2018 Role:PI $808,593.00 Awarded Level:Private Non-Profit

Grant: #T32GM008478 Investigators:Lentsch, Alex 07-01-2018 -06-30-2023 National Institute of General Medical Sciences Host Response to Trauma Research Training Program Role:PI $274,769.00 Active Level:Federal

Grant: #Shriner 2019 Investigators:Lentsch, Alex 01-01-2019 -12-31-2019 Shriners Hospitals for Children - Cincinnati Shriner's Hospital Consulting Agreements, calendar year 2019 Role:PI $412,172.72 Awarded Level:Private Non-Profit

Grant: #R01 GM107625-06A1 Investigators:Caldwell, Charles; Gulbins, Erich; Lentsch, Alex; Pritts, Timothy 02-01-2014 -03-31-2023 National Institutes of Health Red blood cell microparticles and lung inflammation after hemorrhage and resuscitation Role:Collaborator $352,825.00 Awarded Level:Federal

Publications

Peer Reviewed Publications

Solomkin,J.S.; Robinson,C.T.; Cave,C.M.; Ehmer,B.; Lentsch,A.B. (2007. )Alterations in membrane cholesterol cause mobilization of lipid rafts from specific granules and prime human neutrophils for enhanced adherence-dependent oxidant production .Shock, ,28 (3 ),334 -338

Saari,J.T.; Wold,L.E.; Duan,J.; Ren,J.; Carlson,H.L.; Bode,A.M.; Lentsch,A.B.; Zeng,H.; Schuschke,D.A. (2007. )Cardiac nitric oxide synthases are elevated in dietary copper deficiency .Journal of Nutritional Biochemistry, ,18 (7 ),443 -448

Kuboki,S.; Okaya,T.; Schuster,R.; Blanchard,J.; Denenberg,A.; Wong,H.R.; Lentsch,A.B. (2007. )Hepatocyte nf-κb activation is hepatoprotective during ischemia-reperfusion injury and is augmented by ischemic hypothermia .American Journal of Physiology - Gastrointestinal and Liver Physiology, ,292 (1 ),G201 -G207

Caldwell,C.C.; Tschoep,J.; Lentsch,A.B. (2007. )Lymphocyte function during hepatic ischemia/reperfusion injury .Journal of Leukocyte Biology, ,82 (3 ),457 -464

Kuboki,S.; Schuster,R.; Blanchard,J.; Pritts,T.A.; Wong,H.R.; Lentsch,A.B. (2007. )Role of heat shock protein 70 in hepatic ischemia-reperfusion injury in mice .American Journal of Physiology - Gastrointestinal and Liver Physiology, ,292 (4 ),G1141 -G1149

Lentsch,A.B.; Pathrose,P.; Kader,S.; Kuboki,S.; Collins,M.H.; Waltz,S.E. (2007. )The ron receptor tyrosine kinase regulates acute lung injury and suppresses nuclear factor κb activation .Shock, ,27 (3 ),274 -280

Shen,H.; Schuster,R.; Lu,B.; Waltz,S.E.; Lentsch,A.B. (2006. )Critical and opposing roles of the chemokine receptors cxcr2 and cxcr3 in prostate tumor growth .Prostate, ,66 (16 ),1721 -1728

Lentsch,A.B. (2006. )Cxc chemokines and prostate cancer: growth regulators and potential biomarkers .Future Oncology, ,2 (5 ),651 -658

Solomkin,J.S.; Robinson,C.T.; Cave,C.M.; Umanskiy,K.; Matlin,K.; Williams,M.A.; Lentsch,A.B. (2006. )Formation of focal adhesion-like structures in circulating human neutrophils after severe injury: triggering of a tissue-phase response in the vascular space .Shock, ,25 (5 ),440 -445

Mallakin,A.; Kutcher,L.W.; McDowell,S.A.; Kong,S.; Schuster,R.; Lentsch,A.B.; Aronow,B.J.; Leikauf,G.D.; Waltz,S.E. (2006. )Gene expression profiles of mst1r-deficient mice during nickel-induced acute lung injury .American Journal of Respiratory Cell and Molecular Biology, ,34 (1 ),15 -27

Husted,T.L.; Blanchard,J.; Schuster,R.; Shen,H.; Lentsch,A.B. (2006. )Potential role for il-23 in hepatic ischemia/reperfusion injury .Inflammation Research, ,55 (5 ),177 -178

Toledo-Pereyra,L.H.; Lopez-Neblina,F.; Lentsch,A.B.; Anaya-Prado,R.; Romano,S.J.; Ward,P.A. (2006. )Selectin inhibition modulates nf-κb and ap-1 signaling after liver ischemia/reperfusion .Journal of Investigative Surgery, ,19 (5 ),313 -322

Shen,H.; Schuster,R.; Stringer,K.F.; Waltz,S.E.; Lentsch,A.B. (2006. )The duffy antigen/receptor for chemokines (darc) regulates prostate tumor growth .FASEB Journal, ,20 (1 ),59 -64

Husted,T.L.; Lentsch,A.B. (2006. )The role of cytokines in pharmacological modulation of hepatic ischemia/reperfusion injury .Current Pharmaceutical Design, ,12 (23 ),2867 -2873

Husted,T.L.; Govindaswami,M.; Oeltgen,P.R.; Rudich,S.M.; Lentsch,A.B. (2005. )A δ2-opioid agonist inhibits p38 mapk and suppresses activation of murine macrophages .Journal of Surgical Research, ,128 (1 ),45 -49

Okaya,T.; Blanchard,J.; Schuster,R.; Kuboki,S.; Husted,T.; Caldwell,C.C.; Zingarelli,B.; Wong,H.; Solomkin,J.S.; Lentsch,A.B. (2005. )Age-dependent responses to hepatic ischemia/reperfusion injury .Shock, ,24 (5 ),421 -427

Husted,T.L.; Lentsch,A.B. (2005. )Anti-inflammatory approaches to the prevention of ischemia/reperfusion injury in solid organ transplantation .Current Opinion in Investigational Drugs, ,6 (5 ),508 -512

Barone,S.; Okaya,T.; Rudich,S.; Petrovic,S.; Tenrani,K.; Wang,Z.; Zahedi,K.; Casero,R.A.; Lentsch,A.B.; Soleimani,M. (2005. )Distinct and sequential upregulation of genes regulating cell growth and cell cycle progression during hepatic ischemia-reperfusion injury .American Journal of Physiology - Cell Physiology, ,289 (4 58-4 ),C826 -C835

Caldwell,C.C.; Okaya,T.; Martignoni,A.; Husted,T.; Schuster,R.; Lentsch,A.B. (2005. )Divergent functions of cd4+ t lymphocytes in acute liver inflammation and injury after ischemia-reperfusion .American Journal of Physiology - Gastrointestinal and Liver Physiology, ,289 (5 52-5 ),G969 -G976

Okaya,T.; Lentsch,A.B. (2005. )Hepatic expression of s32a/s36a iκbα does not reduce postischemic liver injury .Journal of Surgical Research, ,124 (2 ),244 -249

Thakar,C.V.; Zahedi,K.; Revelo,M.P.; Wang,Z.; Burnham,C.E.; Barone,S.; Bevans,S.; Lentsch,A.B.; Rabb,H.; Soleimani,M. (2005. )Identification of thrombospondin 1 (tsp-1) as a novel mediator of cell injury in kidney ischemia .Journal of Clinical Investigation, ,115 (12 ),3451 -3459

Gordon,S.A.; Lominadze,D.; Saari,J.T.; Lentsch,A.B.; Schuschke,D.A. (2005. )Impaired deformability of copper-deficient neutrophils .Experimental Biology and Medicine, ,230 (8 ),543 -548

Williams,M.A.; Cave,C.M.; Quaid,G.; Robinson,C.; Daly,T.J.; Witt,D.; Lentsch,A.B.; Solomkin,J.S. (2005. )Interleukin 8 dimerization as a mechanism for regulation of neutrophil adherence-dependent oxidant production .Shock, ,23 (4 ),371 -376

Mayhew,C.N.; Bosco,E.E.; Fox,S.R.; Okaya,T.; Tarapore,P.; Schwemberger,S.J.; Babcock,G.F.; Lentsch,A.B.; Fukasawa,K.; Knudsen,E.S. (2005. )Liver-specific prb loss results in ectopic cell cycle entry and aberrant ploidy .Cancer Research, ,65 (11 ),4568 -4577

Okaya,T.; Holthaus,R.; Kato,A.; Lentsch,A.B. (2004. )Involvement of the neuropeptide substance p in lung inflammation induced by hepatic ischemia/reperfusion .Inflammation Research, ,53 (6 ),257 -261

Okaya,T.; Lentsch,A.B. (2004. )Peroxisome proliferator-activated receptor-α regulates postischemic liver injury .American Journal of Physiology - Gastrointestinal and Liver Physiology, ,286 (4 49-4 ),G606 -G612

Shen,H.; Lentsch,A.B. (2004. )Progressive dysregulation of transcription factors nf-κb and stat1 in prostate cancer cells causes proangiogenic production of cxc chemokines .American Journal of Physiology - Cell Physiology, ,286 (4 55-4 ),C840 -C847

Okaya,T.; Lentsch,A.B. (2003. )Cytokine cascades and the hepatic inflammatory response to ischemia and reperfusion .Journal of Investigative Surgery, ,16 (3 ),141 -147

Kato,A.; Okaya,T.; Lentsch,A.B. (2003. )Endogenous il-13 protects hepatocytes and vascular endothelial cells during ischemia/reperfusion injury .Hepatology, ,37 (2 ),304 -312

Umanskiy,K.; Robinson,C.; Cave,C.; Williams,M.A.; Lentsch,A.B.; Cuschieri,J.; Solomkin,J.S. (2003. )Nadph oxidase activation in fibronectin adherent human neutrophils: a potential role for β1 integrin ligation .Surgery, ,134 (2 ),378 -383

Guo,R.-F.; Lentsch,A.B.; Sarma,J.V.; Sun,L.; Riedemann,N.C.; McClintock,S.D.; McGuire,S.R.; Van Rooijen,N.; Ward,P.A. (2002. )Activator protein-1 activation in acute lung injury .American Journal of Pathology, ,161 (1 ),275 -282

Ward,P.A.; Lentsch,A.B. (2002. )Endogenous regulation of the acute inflammatory response .Molecular and Cellular Biochemistry, ,234-235 ,225 -228

Kato,A.; Edwards,M.J.; Lentsch,A.B. (2002. )Gene deletion of nf-κb p50 does not alter the hepatic inflammatory response to ischemia/reperfusion .Journal of Hepatology, ,37 (1 ),48 -55

Anaya-Prado,R.; Toledo-Pereyra,L.H.; Lentsch,A.B.; Ward,P.A. (2002. )Ischemia/reperfusion injury .Journal of Surgical Research, ,105 (2 ),248 -258

Kato,A.; Singh,S.; McLeish,K.R.; Edwards,M.J.; Lentsch,A.B. (2002. )Mechanisms of hypothermic protection against ischemic liver injury in mice .American Journal of Physiology - Gastrointestinal and Liver Physiology, ,282 (4 45-4 ),G608 -G616

Kato,A.; Graul-Layman,A.; Edwards,M.J.; Lentsch,A.B. (2002. )Promotion of hepatic ischemia/reperfusion injury by il-12 is independent of stat4 .Transplantation, ,73 (7 ),1142 -1145

Kato,A.; Gabay,C.; Okaya,T.; Lentsch,A.B. (2002. )Specific role of interleukin-1 in hepatic neutrophil recruitment after ischemia/reperfusion .American Journal of Pathology, ,161 (5 ),1797 -1803

Lentsch,A.B. (2002. )The duffy antigen/receptor for chemokines (darc) and prostate cancer. a role as clear as black and white? .FASEB Journal, ,16 (9 ),1093 -1095

Schuschke,D.A.; Percival,S.S.; Lominadze,D.; Saari,J.T.; Lentsch,A.B. (2002. )Tissue-specific icam-1 expression and neutrophil transmigration in the copper-deficient rat .Inflammation, ,26 (6 ),297 -303

Lentsch,A.B.; Kato,A.; Saari,J.T.; Schuschke,D.A. (2001. )Augmented metalloproteinase activity and acute lung injury in copper-deficient rats .American Journal of Physiology - Lung Cellular and Molecular Physiology, ,281 (2 25-2 ),L387 -L393

Lentsch,A.B.; Ward,P.A. (2001. )Regulation of experimental lung inflammation .Respiration Physiology, ,128 (1 ),17 -22

Guo,R.-F.; Lentsch,A.B.; Warner,R.L.; Huber-Lang,M.; Sarma,J.V.; Hlaing,T.; Shi,M.M.; Lukacs,N.W.; Ward,P.A. (2001. )Regulatory effects of eotaxin on acute lung inflammatory injury .Journal of Immunology, ,166 (8 ),5208 -5218

Lentsch,A.B.; Kato,A.; Davis,B.; Wang,W.; Chao,C.; Edwards,M.J. (2001. )Stat4 and stat6 regulate systemic inflammation and protect against lethal endotoxemia .Journal of Clinical Investigation, ,108 (10 ),1475 -1482

Godshall,C.J.; Lentsch,A.B.; Peyton,J.C.; Scott,M.J.; Cheadle,W.G. (2001. )Stat4 is required for antibacterial defense but enhances mortality during polymicrobial sepsis .Clinical and Diagnostic Laboratory Immunology, ,8 (6 ),1044 -1048

Mulligan,M.S.; Lentsch,A.B.; Huber-Lang,M.; Guo,R.-F.; Sarma,V.; Wright,C.D.; Ulich,T.R.; Ward,P.A. (2000. )Anti-inflammatory effects of mutant forms of secretory leukocyte protease inhibitor .American Journal of Pathology, ,156 (3 ),1033 -1039

Dawson,T.C.; Lentsch,A.B.; Wang,Z.; Cowhig,J.E.; Rot,A.; Maeda,N.; Peiper,S.C. (2000. )Exaggerated response to endotoxin in mice lacking the duffy antigen/receptor for chemokines (darc) .Blood, ,96 (5 ),1681 -1684

Lentsch,A.B.; Kato,A.; Yoshidome,H.; McMasters,K.M.; Edwards,M.J. (2000. )Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury .Hepatology, ,32 (2 ),169 -173

Yoshidome,H.; Miyazaki,M.; Shimizu,H.; Ito,H.; Nakagawa,K.; Ambiru,S.; Nakajima,N.; Edwards,M.J.; Lentsch,A.B. (2000. )Obstructive jaundice impairs hepatic sinusoidal endothelial cell function and renders liver susceptible to hepatic ischemia/reperfusion .Journal of Hepatology, ,33 (1 ),59 -67

Kato,A.; Yoshidome,H.; Edwards,M.J.; Lentsch,A.B. (2000. )Reduced hepatic ischemia/reperfusion injury by il-4: potential anti- inflammatory role of stat6 .Inflammation Research, ,49 (6 ),275 -279

Lentsch,A.B. (2000. )Regulation of acute inflammation by the duffy antigen/ receptor for chemokines (darc): exaggerated response to lps in knockout mice and protection in transgenic mice programmed for endothelial expression .Blood, ,96 (11 PART I ),

Lentsch,A.B.; Ward,P.A. (2000. )Regulation of inflammatory vascular damage .Journal of Pathology, ,190 (3 ),343 -348

Kato,A.; Yoshidome,H.; Edwards,M.J.; Lentsch,A.B. (2000. )Regulation of liver inflammatory injury by signal transducer and activator of transcription-6 .American Journal of Pathology, ,157 (1 ),297 -302

Molestina,R.E.; Miller,R.D.; Lentsch,A.B.; Ramirez,J.A.; Summersgill,J.T. (2000. )Requirement for nf-κb in transcriptional activation of monocyte chemotactic protein 1 by chlamydia pneumoniae in human endothelial cells .Infection and Immunity, ,68 (7 ),4282 -4288

Bless,N.M.; Huber-Lang,M.; Guo,R.-F.; Warner,R.L.; Schmal,H.; Czermak,B.J.; Shanley,T.P.; Crouch,L.D.; Lentsch,A.B.; Sarma,V.; Mulligan,M.S.; Friedl,H.P.; Ward,P.A. (2000. )Role of cc chemokines (macrophage inflammatory protein-1β, monocyte chemoattractant protein-1, rantes) in acute lung injury in rats .Journal of Immunology, ,164 (5 ),2650 -2659

Lentsch,A.B.; Ward,P.A. (2000. )The nfκb/iκb system in acute inflammation .Archivum Immunologiae et Therapiae Experimentalis, ,48 (2 ),59 -63

Lentsch,A.B.; Ward,P.A. (1999. )Activation and regulation of nfκb during acute inflammation .Clinical Chemistry and Laboratory Medicine, ,37 (3 ),205 -208

Yoshidome,H.; Lentsch,A.B.; Cheadle,W.G.; Miller,F.N.; Edwards,M.J. (1999. )Enhanced pulmonary expression of cxc chemokines during hepatic ischemia/reperfusion-induced lung injury in mice .Journal of Surgical Research, ,81 (1 ),33 -37

Lentsch,A.B.; Czermak,B.J.; Bless,N.M.; Van Rooijen,N.; Ward,P.A. (1999. )Essential role of alveolar macrophages in intrapulmonary activation of nf-κb .American Journal of Respiratory Cell and Molecular Biology, ,20 (4 ),692 -698

Yoshidome,H.; Kato,A.; Miyazaki,M.; Edwards,M.J.; Lentsch,A.B. (1999. )Il-13 activates stat6 and inhibits liver injury induced by ischemia/reperfusion .American Journal of Pathology, ,155 (4 ),1059 -1064

Lentsch,A.B.; Jordan,J.A.; Czermak,B.J.; Diehl,K.M.; Younkin,E.M.; Sarma,V.; Ward,P.A. (1999. )Inhibition of nf-κb activation and augmentation of iκbβ by secretory leukocyte protease inhibitor during lung inflammation .American Journal of Pathology, ,154 (1 ),239 -247

Yoshidome,H.; Kato,A.; Edwards,M.J.; Lentsch,A.B. (1999. )Interleukin-10 inhibits pulmonary nf-κb activation and lung injury induced by hepatic ischemia-reperfusion .American Journal of Physiology - Lung Cellular and Molecular Physiology, ,277 (5 21-5 ),L919 -L923

Yoshidome,H.; Kato,A.; Edwards,M.J.; Lentsch,A.B. (1999. )Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: implications of a central role for nuclear factor κb .Hepatology, ,30 (1 ),203 -208

Lentsch,A.B.; Miller,F.N.; Edwards,M.J. (1999. )Mechanisms of leukocyte-mediated tissue injury induced by interleukin-2 .Cancer Immunology Immunotherapy, ,47 (5 ),243 -248

Lentsch,A.B.; Czermak,B.J.; Jordan,J.A.; Ward,P.A. (1999. )Regulation of acute lung inflammatory injury by endogenous il-13 .Journal of Immunology, ,162 (2 ),1071 -1076

Lentsch,A.B.; Crouch,L.D.; Jordan,J.A.; Czermak,B.J.; Yun,E.C.; Renfeng,G.; Sarma,V.; Diehl,K.M.; Ward,P.A. (1999. )Regulatory effects of interleukin-11 during acute lung inflammatory injury .Journal of Leukocyte Biology, ,66 (1 ),151 -157

Lentsch,A.B.; Yoshidome,H.; Kato,A.; Warner,R.L.; Cheadle,W.G.; Ward,P.A.; Edwards,M.J. (1999. )Requirement for interleukin-12 in the pathogenesis of warm hepatic ischemia/reperfusion injury in mice .Hepatology, ,30 (6 ),1448 -1453

Bless,N.M.; Waener,R.L.; Padgaonkar,V.A.; Lentsch,A.B.; Czermak,B.J.; Schmal,H.; Friedl,H.P.; Ward,P.A. (1999. )Roles for c-x-c chemokines and c5a in lung injury after hindlimb ischemia-reperfusion .American Journal of Physiology - Lung Cellular and Molecular Physiology, ,276 (1 20-1 ),L57 -L63

Lentsch,A.B.; Yoshidome,H.; Warner,R.L.; Ward,P.A.; Edwards,M.J. (1999. )Secretory leukocyte protease inhibitor in mice regulates local and remote organ inflammatory injury induced by hepatic ischemia/reperfusion .Gastroenterology, ,117 (4 ),953 -961

Czermak,B.J.; Lentsch,A.B.; Bless,N.M.; Schmal,H.; Friedl,H.P.; Ward,P.A. (1999. )Synergistic enhancement of chemokine generation and lung injury by c5a or the membrane attack complex of complement .American Journal of Pathology, ,154 (5 ),1513 -1524

Ward,P.A.; Lentsch,A.B. (1999. )The acute inflammatory response and its regulation .Archives of Surgery, ,134 (6 ),666 -669

Lentsch,A.B.; Ward,P.A. (1999. )Understanding the pathogenesis of inflammation using rodent models: identification of a transcription factor (nfκb) necessary for development of inflammatory injury .ILAR Journal, ,40 (4 ),151 -156

Lentsch,A.B.; Yoshidome,H.; Cheadle,W.G.; Miller,F.N.; Edwards,M.J. (1998. )Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and kupffer cells .Hepatology, ,27 (2 ),507 -512

Mulligan,M.S.; Lentsch,A.B.; Shanley,T.P.; Miyasaka,M.; Johnson,K.J.; Ward,P.A. (1998. )Cytokine and adhesion molecule requirements for lung injury induced by anti-glomerular basement membrane antibody .Inflammation, ,22 (4 ),403 -417

Mulligan,M.S.; Lentsch,A.B.; Miyasaka,M.; Ward,P.A. (1998. )Cytokine and adhesion molecule requirements for neutrophil recruitment during glycogen-induced peritonitis .Inflammation Research, ,47 (6 ),251 -255

Lentsch,A.B.; Bless,N.M.; Czermak,B.J.; Ward,P.A. (1998. )Determinants of nf-κb activation in acute lung injury .FASEB Journal, ,12 (5 ),

Bless,N.M.; Tojo,S.J.; Kawarai,H.; Natsume,Y.; Lentsch,A.B.; Padgaonkar,V.A.; Czermak,B.J.; Schmal,H.; Friedl,H.P.; Ward,P.A. (1998. )Differing patterns of p-selectin expression in lung injury .American Journal of Pathology, ,153 (4 ),1113 -1122

Mulligan,M.S.; Lentsch,A.B.; Ward,P.A. (1998. )In vivo recruitment of neutrophils: consistent requirements for l-arginine and variable requirements for complement and adhesion molecules .Inflammation, ,22 (3 ),327 -339

Lentsch,A.B.; Czermak,B.J.; Bless,N.M.; Ward,P.A. (1998. )Nf-κb activation during igg immune complex-induced lung injury: requirements for tnf-α and il-1β but not complement .American Journal of Pathology, ,152 (5 ),1327 -1336

Lentsch,A.B.; Edwards,M.J.; Sims,D.E.; Miller,F.N. (1998. )Nw-nitro-l-arginine methyl ester inhibits inflammatory liver injury induced by interleukin-2 .Journal of Leukocyte Biology, ,63 (1 ),22 -30

Czermak,B.J.; Lentsch,A.B.; Bless,N.M.; Schmal,H.; Friedl,H.P.; Ward,P.A. (1998. )Role of complement in in vitro and in vivo lung inflammatory reactions .Journal of Leukocyte Biology, ,64 (1 ),40 -48

Schmal,H.; Czermak,B.J.; Lentsch,A.B.; Bless,N.M.; Beck-Schimmer,B.; Friedl,H.P.; Ward,P.A. (1998. )Soluble icam-1 activates lung macrophages and enhances lung injury .Journal of Immunology, ,161 (7 ),3685 -3693

Lentsch,A.B.; Nakagawa,K.; Yoshidome,H.; Gerassimides,A.; Miller,F.N.; Edwards,M.J. (1997. )Distinct biologisal activities of recombinant forms of human interleukin-2 in vivo .Cancer Immunology Immunotherapy, ,43 (6 ),331 -336

Lentsch,A.B.; Shanley,T.P.; Sarma,V.; Ward,P.A. (1997. )In vivo suppression of nf-κb and preservation of iκbα by interleukin- 10 and interleukin-13 .Journal of Clinical Investigation, ,100 (10 ),2443 -2448

Lentsch,A.B.; Shanley,T.P.; Ward,P.A. (1997. )Interleukin-10 protects against igg immune complex-induced lung injury through suppression of nf-κb .FASEB Journal, ,11 (3 ),

Lentsch,A.B.; Miller,F.N.; Edwards,M.J. (1997. )Interleukin-2-induced hepatic injury involves temporal patterns of cell adhesion in the microcirculation .American Journal of Physiology - Gastrointestinal and Liver Physiology, ,272 (4 35-4 ),G727 -G731

Crouch,L.D.; Lentsch,A.B.; Warner,R.L.; Johnson,K.J.; Ward,P.A. (1997. )Regulatory effects of adrenal gland products in igg immune complex acute lung injury .FASEB Journal, ,11 (3 ),

Lentsch,A.B.; Edwards,M.J.; Sims,D.E.; Nakagawa,K.; Wellhausen,S.R.; Miller,F.N. (1996. )Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce toxicity in c3h/hen mice .Journal of Leukocyte Biology, ,60 (1 ),51 -57

Lentsch,A.B.; Edwards,M.J.; Sims,D.E.; Nakagawa,K.; Miller,F.N. (1996. )Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce toxicity in mice .FASEB Journal, ,10 (3 ),

Lentsch,A.B.; Edwards,M.J.; Miller,F.N. (1996. )Interleukin-2 induces increased platelet-endothelium interactions: a potential mechanism of toxicity .Journal of Laboratory and Clinical Medicine, ,128 (1 ),75 -82

Nakagawa,K.; Miller,F.N.; Sims,D.E.; Lentsch,A.B.; Miyazaki,M.; Edwards,M.J. (1996. )Mechanisms of interleukin-2-induced hepatic toxicity .Cancer Research, ,56 (3 ),507 -510

Edwards,M.J.; Gable,D.R.; Lentsch,A.B.; Richardson,J.D. (1996. )The rationale for esophagectomy as the optimal therapy for barrett's esophagus with high-grade dysplasia .Annals of Surgery, ,223 (5 ),585 -591

Anderson,J.A.; Lentsch,A.B.; Hadjiminas,D.J.; Miller,F.N.; Martin,A.W.; Nakagawa,K.; Edwards,M.J. (1996. )The role of cytokines, adhesion molecules, and chemokines in interleukin-2-induced lymphocytic infiltration in c57bl/6 mice .Journal of Clinical Investigation, ,97 (8 ),1952 -1959

Lindberg,R.A.; Slaaf,D.W.; Lentsch,A.B.; Miller,F.N. (1994. )Involvement of nitric oxide and cyclooxygenase products in photoactivation-induced microvascular occlusion .Microvascular Research, ,47 (2 ),203 -221

Prakash, Priya S; Caldwell, Charles C; Lentsch, Alex B; Pritts, Timothy A; Robinson, Bryce R H (2012. )Human microparticles generated during sepsis in patients with critical illness are neutrophil-derived and modulate the immune response.The journal of trauma and acute care surgery, ,73 (2 ),401-6; discussion 40

Tevar, Amit D; Clarke, Calissia; Wang, Jiang; Rudich, Steven M; Woodle, E Steve; Lentsch, Alex B; Edwards, Michael L (2010. )Clinical review of nonalcoholic steatohepatitis in liver surgery and transplantation.Journal of the American College of Surgeons, ,210 (4 ),515-26

Husted, Thomas L; Lentsch, Alex B (2006. )The role of cytokines in pharmacological modulation of hepatic ischemia/reperfusion injury. Current pharmaceutical design, ,12 (23 ),2867-73

Lentsch, A B; Jordan, J A; Czermak, B J; Diehl, K M; Younkin, E M; Sarma, V; Ward, P A (1999. )Inhibition of NF-kappaB activation and augmentation of IkappaBbeta by secretory leukocyte protease inhibitor during lung inflammation. The American journal of pathology, ,154 (1 ),239-47

Stewart, Rachel K; Dangi, Anil; Huang, Chao; Murase, Noriko; Kimura, Shoko; Stolz, Donna B; Wilson, Gregory C; Lentsch, Alex B; Gandhi, Chandrashekhar R (2014. )A novel mouse model of depletion of stellate cells clarifies their role in ischemia/reperfusion- and endotoxin-induced acute liver injury.Journal of hepatology, ,60 (2 ),298-305

Goodman, Michael D; Makley, Amy T; Campion, Eric M; Friend, Lou Ann W; Lentsch, Alex B; Pritts, Timothy A (2013. )Preinjury alcohol exposure attenuates the neuroinflammatory response to traumatic brain injury.The Journal of surgical research, ,184 (2 ),1053-8

Yang, Sung H; Gustafson, Josh; Gangidine, Matt; Stepien, David; Schuster, Rebecca; Pritts, Timothy A; Goodman, Michael D; Remick, Daniel G; Lentsch, Alex B (2013. )A murine model of mild traumatic brain injury exhibiting cognitive and motor deficits.The Journal of surgical research, ,184 (2 ),981-8

Uriarte, Silvia M; Rane, Madhavi J; Merchant, Michael L; Jin, Shunying; Lentsch, Alex B; Ward, Richard A; McLeish, Kenneth R (2013. )Inhibition of neutrophil exocytosis ameliorates acute lung injury in rats.Shock (Augusta, Ga.), ,39 (3 ),286-92

Van Sweringen, Heather L; Sakai, Nozomu; Quillin, Ralph C; Bailey, Jeff; Schuster, Rebecca; Blanchard, John; Goetzman, Holly; Caldwell, Charles C; Edwards, Michael J; Lentsch, Alex B (2013. )Roles of hepatocyte and myeloid CXC chemokine receptor-2 in liver recovery and regeneration after ischemia/reperfusion in mice.Hepatology (Baltimore, Md.), ,57 (1 ),331-8

Sakai, Nozomu; Van Sweringen, Heather L; Quillin, R Cutler; Schuster, Rebecca; Blanchard, John; Burns, Justin M; Tevar, Amit D; Edwards, Michael J; Lentsch, Alex B (2012. )Interleukin-33 is hepatoprotective during liver ischemia/reperfusion in mice.Hepatology (Baltimore, Md.), ,56 (4 ),1468-78

Sakai, Nozomu; Van Sweringen, Heather L; Belizaire, Ritha M; Quillin, Ralph Cutler; Schuster, Rebecca; Blanchard, John; Burns, Justin M; Tevar, Amit D; Edwards, Michael J; Lentsch, Alex B (2012. )Interleukin-37 reduces liver inflammatory injury via effects on hepatocytes and non-parenchymal cells.Journal of gastroenterology and hepatology, ,27 (10 ),1609-16

Zahedi, Kamyar; Barone, Sharon L; Xu, Jie; Steinbergs, Nora; Schuster, Rebecca; Lentsch, Alex B; Amlal, Hassane; Wang, Jiang; Casero, Robert A; Soleimani, Manoocher (2012. )Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCl4-induced acute liver injury.American journal of physiology. Gastrointestinal and liver physiology, ,303 (5 ),G546-60

Belizaire, Ritha M; Makley, Amy T; Campion, Eric M; Sonnier, Dennis I; Goodman, Michael D; Dorlac, Warren C; Friend, Lou Ann; Lentsch, Alex B; Pritts, Timothy A (2012. )Resuscitation with washed aged packed red blood cell units decreases the proinflammatory response in mice after hemorrhage.The journal of trauma and acute care surgery, ,73 (2 Suppl 1 ),S128-33

Belizaire, Ritha M; Prakash, Priya S; Richter, Jillian R; Robinson, Bryce R; Edwards, Michael J; Caldwell, Charles C; Lentsch, Alex B; Pritts, Timothy A (2012. )Microparticles from stored red blood cells activate neutrophils and cause lung injury after hemorrhage and resuscitation.Journal of the American College of Surgeons, ,214 (4 ),648-55; discussion 6

Sakai, Nozomu; Van Sweringen, Heather L; Schuster, Rebecca; Blanchard, John; Burns, Justin M; Tevar, Amit D; Edwards, Michael J; Lentsch, Alex B (2012. )Receptor activator of nuclear factor-?B ligand (RANKL) protects against hepatic ischemia/reperfusion injury in mice.Hepatology (Baltimore, Md.), ,55 (3 ),888-97

Huber, Nathan L; Bailey, Stephanie R; Schuster, Rebecca; Ogle, Cora K; Lentsch, Alex B; Pritts, Timothy A Prior thermal injury accelerates endotoxin-induced inflammatory cytokine production and intestinal nuclear factor-?B activation in mice.Journal of burn care & research : official publication of the American Burn Association, ,33 (2 ),279-85

Lentsch, Alex B (2012. )Regulatory mechanisms of injury and repair after hepatic ischemia/reperfusion.Scientifica, ,2012 ,513192

Sonnier, Dennis I; Bailey, Stephanie R; Schuster, Rebecca M; Gangidine, Matthew M; Lentsch, Alex B; Pritts, Timothy A (2012. )Proinflammatory chemokines in the intestinal lumen contribute to intestinal dysfunction during endotoxemia.Shock (Augusta, Ga.), ,37 (1 ),63-9

Clarke, Callisia; Sakai, Nozomu; Tevar, Amit D; Schuster, Rebecca; Edwards, Michael J; Lentsch, Alex B (2011. )STAT3 does not regulate acute liver injury after ischemia/reperfusion.The Journal of surgical research, ,171 (2 ),814-8

Van Sweringen, Heather L; Sakai, Nozomu; Tevar, Amit D; Burns, Justin M; Edwards, Michael J; Lentsch, Alex B (2011. )CXC chemokine signaling in the liver: impact on repair and regeneration.Hepatology (Baltimore, Md.), ,54 (4 ),1445-53

Sonnier, Dennis I; Makley, Amy T; Friend, Lou Ann W; Bailey, Stephanie R; Lentsch, Alex B; Pritts, Timothy A (2011. )Hemorrhagic shock induces a proinflammatory milieu in the gut lumen.The Journal of surgical research, ,170 (2 ),272-9

Sakai, Nozomu; Shin, Thomas; Schuster, Rebecca; Blanchard, John; Lentsch, Alex B; Johnson, William Thomas; Schuschke, Dale A (2011. )Marginal copper deficiency increases liver neutrophil accumulation after ischemia/reperfusion in rats.Biological trace element research, ,142 (1 ),47-54

Tevar, Amit D; Clarke, Callisia N; Schuster, Rebecca; Wang, Jiang; Edwards, Michael J; Lentsch, Alex B (2011. )The effect of hepatic ischemia reperfusion injury in a murine model of nonalcoholic steatohepatitis.The Journal of surgical research, ,169 (1 ),e7-14

Clarke, Callisia; Kuboki, Satoshi; Sakai, Nozomu; Kasten, Kevin R; Tevar, Amit D; Schuster, Rebecca; Blanchard, John; Caldwell, Charles C; Edwards, Michael J; Lentsch, Alex B (2011. )CXC chemokine receptor-1 is expressed by hepatocytes and regulates liver recovery after hepatic ischemia/reperfusion injury.Hepatology (Baltimore, Md.), ,53 (1 ),261-71

Goodman, Michael D; Makley, Amy T; Huber, Nathan L; Clarke, Callisia N; Friend, Lou Ann W; Schuster, Rebecca M; Bailey, Stephanie R; Barnes, Stephen L; Dorlac, Warren C; Johannigman, Jay A; Lentsch, Alex B; Pritts, Timothy A (2011. )Hypobaric hypoxia exacerbates the neuroinflammatory response to traumatic brain injury.The Journal of surgical research, ,165 (1 ),30-7

Goodman, Michael D; Makley, Amy T; Lentsch, Alex B; Barnes, Stephen L; Dorlac, Gina R; Dorlac, Warren C; Johannigman, Jay A; Pritts, Timothy A (2010. )Traumatic brain injury and aeromedical evacuation: when is the brain fit to fly?.The Journal of surgical research, ,164 (2 ),286-93

Sonnier, Dennis I; Bailey, Stephanie R; Schuster, Rebecca M; Lentsch, Alex B; Pritts, Timothy A (2010. )TNF-? induces vectorial secretion of IL-8 in Caco-2 cells.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, ,14 (10 ),1592-9

Sakai, Nozomu; Clarke, Callisia N; Schuster, Rebecca; Blanchard, John; Tevar, Amit D; Edwards, Michael J; Lentsch, Alex B (2010. )Portal vein ligation accelerates tumor growth in ligated, but not contralateral lobes. World journal of gastroenterology : WJG, ,16 (30 ),3816-26

Huber, Nathan L; Bailey, Stephanie R; Schuster, Rebecca M; Ogle, Cora K; Lentsch, Alex B; Pritts, Timothy A (2010. )Remote thermal injury increases LPS-induced intestinal IL-6 production.The Journal of surgical research, ,160 (2 ),190-5

Kasten, Kevin R; Goetzman, Holly S; Reid, Maria R; Rasper, Alison M; Adediran, Samuel G; Robinson, Chad T; Cave, Cindy M; Solomkin, Joseph S; Lentsch, Alex B; Johannigman, Jay A; Caldwell, Charles C (2010. )Divergent adaptive and innate immunological responses are observed in humans following blunt trauma.BMC immunology, ,11 ,4

Clarke, Callisia N; Kuboki, Satoshi; Tevar, Amit; Lentsch, Alex B; Edwards, Michael (2009. )CXC chemokines play a critical role in liver injury, recovery, and regeneration.American journal of surgery, ,198 (3 ),415-9

Zingarelli, Basilia; Hake, Paul W; O'Connor, Michael; Burroughs, Timothy J; Wong, Hector R; Solomkin, Joseph S; Lentsch, Alex B (2009. )Lung injury after hemorrhage is age dependent: role of peroxisome proliferator-activated receptor gamma.Critical care medicine, ,37 (6 ),1978-87

Huber, Nadine; Sakai, Nozomu; Eismann, Thorsten; Shin, Thomas; Kuboki, Satoshi; Blanchard, John; Schuster, Rebecca; Edwards, Michael J; Wong, Hector R; Lentsch, Alex B (2009. )Age-related decrease in proteasome expression contributes to defective nuclear factor-kappaB activation during hepatic ischemia/reperfusion.Hepatology (Baltimore, Md.), ,49 (5 ),1718-28

Golab, Fereshteh; Kadkhodaee, Mehri; Zahmatkesh, Maryam; Hedayati, Mehdi; Arab, Hossein; Schuster, Rebecca; Zahedi, Kamyar; Lentsch, Alex B; Soleimani, Manoocher (2009. )Ischemic and non-ischemic acute kidney injury cause hepatic damage.Kidney international, ,75 (8 ),783-92

Eismann, Thorsten; Huber, Nadine; Shin, Thomas; Kuboki, Satoshi; Galloway, Elizabeth; Wyder, Michael; Edwards, Michael J; Greis, Kenneth D; Shertzer, Howard G; Fisher, Aron B; Lentsch, Alex B (2009. )Peroxiredoxin-6 protects against mitochondrial dysfunction and liver injury during ischemia-reperfusion in mice.American journal of physiology. Gastrointestinal and liver physiology, ,296 (2 ),G266-74

Lewis, Jaime D; Pritts, Timothy A; Lentsch, Alex B; Edwards, Michael J (2009. )The University of Cincinnati College of Medicine Department of Surgery. The American surgeon, ,75 (2 ),113-9

Flierl, Michael A; Rittirsch, Daniel; Nadeau, Brian A; Sarma, J Vidya; Day, Danielle E; Lentsch, Alex B; Huber-Lang, Markus S; Ward, Peter A (2009. )Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response.PloS one, ,4 (2 ),e4414

Caldwell, Charles C; Lentsch, Alex B (2008. )Ischemia-driven expression of CD73 confers tissue protection during liver ischemia/reperfusion.Gastroenterology, ,135 (5 ),1460-2

Kuboki, Satoshi; Shin, Thomas; Huber, Nadine; Eismann, Thorsten; Galloway, Elizabeth; Schuster, Rebecca; Blanchard, John; Edwards, Michael J; Lentsch, Alex B (2008. )Hepatocyte signaling through CXC chemokine receptor-2 is detrimental to liver recovery after ischemia/reperfusion in mice.Hepatology (Baltimore, Md.), ,48 (4 ),1213-23

Shin, Thomas; Kuboki, Satoshi; Lentsch, Alex B (2008. )Roles of nuclear factor-kappaB in postischemic liver.Hepatology research : the official journal of the Japan Society of Hepatology, ,38 (5 ),429-40

Tschöp, Johannes; Martignoni, André; Goetzman, Holly S; Choi, Lisa G; Wang, Quan; Noel, John G; Ogle, Cora K; Pritts, Timothy A; Johannigman, Jay A; Lentsch, Alex B; Caldwell, Charles C (2008. )Gammadelta T cells mitigate the organ injury and mortality of sepsis.Journal of leukocyte biology, ,83 (3 ),581-8

Kuboki, Satoshi; Shin, Thomas; Huber, Nadine; Eismann, Thorsten; Galloway, Elizabeth; Schuster, Rebecca; Blanchard, John; Zingarelli, Basilia; Lentsch, Alex B (2008. )Peroxisome proliferator-activated receptor-gamma protects against hepatic ischemia/reperfusion injury in mice.Hepatology (Baltimore, Md.), ,47 (1 ),215-24

Caldwell, Charles C; Tschoep, Johannes; Lentsch, Alex B (2007. )Lymphocyte function during hepatic ischemia/reperfusion injury.Journal of leukocyte biology, ,82 (3 ),457-64

Solomkin, Joseph S; Robinson, Chad T; Cave, Cynthia M; Ehmer, Birgit; Lentsch, Alex B (2007. )Alterations in membrane cholesterol cause mobilization of lipid rafts from specific granules and prime human neutrophils for enhanced adherence-dependent oxidant production.Shock (Augusta, Ga.), ,28 (3 ),334-8

Kuboki, Satoshi; Schuster, Rebecca; Blanchard, John; Pritts, Timothy A; Wong, Hector R; Lentsch, Alex B (2007. )Role of heat shock protein 70 in hepatic ischemia-reperfusion injury in mice.American journal of physiology. Gastrointestinal and liver physiology, ,292 (4 ),G1141-9

Lentsch, Alex B; Pathrose, Peterson; Kader, Sarah; Kuboki, Satoshi; Collins, Margaret H; Waltz, Susan E (2007. )The Ron receptor tyrosine kinase regulates acute lung injury and suppresses nuclear factor kappaB activation.Shock (Augusta, Ga.), ,27 (3 ),274-80

Kuboki, Satoshi; Okaya, Tomohisa; Schuster, Rebecca; Blanchard, John; Denenberg, Alvin; Wong, Hector R; Lentsch, Alex B (2007. )Hepatocyte NF-kappaB activation is hepatoprotective during ischemia-reperfusion injury and is augmented by ischemic hypothermia.American journal of physiology. Gastrointestinal and liver physiology, ,292 (1 ),G201-7

Shen, Hui; Schuster, Rebecca; Lu, Bao; Waltz, Susan E; Lentsch, Alex B (2006. )Critical and opposing roles of the chemokine receptors CXCR2 and CXCR3 in prostate tumor growth.The Prostate, ,66 (16 ),1721-8

Lentsch, Alex B (2006. )CXC chemokines and prostate cancer: growth regulators and potential biomarkers.Future oncology (London, England), ,2 (5 ),651-8

Toledo-Pereyra, Luis H; Lopez-Neblina, Fernando; Lentsch, Alex B; Anaya-Prado, Roberto; Romano, Suzanne J; Ward, Peter A Selectin inhibition modulates NF-kappa B and AP-1 signaling after liver ischemia/reperfusion.Journal of investigative surgery : the official journal of the Academy of Surgical Research, ,19 (5 ),313-22

Husted, T L; Blanchard, J; Schuster, R; Shen, H; Lentsch, A B (2006. )Potential role for IL-23 in hepatic ischemia/reperfusion injury.Inflammation research : official journal of the European Histamine Research Society ... [et al.], ,55 (5 ),177-8

Thakar, Charuhas V; Zahedi, Kamyar; Revelo, Monica P; Wang, Zhaohui; Burnham, Charles E; Barone, Sharon; Bevans, Shannon; Lentsch, Alex B; Rabb, Hamid; Soleimani, Manoocher (2005. )Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney ischemia.The Journal of clinical investigation, ,115 (12 ),3451-9

Okaya, Tomohisa; Blanchard, John; Schuster, Rebecca; Kuboki, Satoshi; Husted, Thomas; Caldwell, Charles C; Zingarelli, Basilia; Wong, Hector; Solomkin, Joseph S; Lentsch, Alex B (2005. )Age-dependent responses to hepatic ischemia/reperfusion injury. Shock (Augusta, Ga.), ,24 (5 ),421-7

Gordon, Sharon A; Lominadze, David; Saari, Jack T; Lentsch, Alex B; Schuschke, Dale A (2005. )Impaired deformability of copper-deficient neutrophils. Experimental biology and medicine (Maywood, N.J.), ,230 (8 ),543-8

Husted, Thomas L; Govindaswami, Meera; Oeltgen, Peter R; Rudich, Steven M; Lentsch, Alex B (2005. )A delta2-opioid agonist inhibits p38 MAPK and suppresses activation of murine macrophages.The Journal of surgical research, ,128 (1 ),45-9

Mayhew, Christopher N; Bosco, Emily E; Fox, Sejal R; Okaya, Tomohisa; Tarapore, Pheruza; Schwemberger, Sandy J; Babcock, George F; Lentsch, Alex B; Fukasawa, Kenji; Knudsen, Erik S (2005. )Liver-specific pRB loss results in ectopic cell cycle entry and aberrant ploidy.Cancer research, ,65 (11 ),4568-77

Okaya, Tomohisa; Lentsch, Alex B (2005. )Hepatic expression of S32A/S36A IkappaBalpha does not reduce postischemic liver injury.The Journal of surgical research, ,124 (2 ),244-9

Williams, Mark A; Cave, Cindy M; Quaid, Gina; Robinson, Chad; Daly, Thomas J; Witt, Dan; Lentsch, Alex B; Solomkin, Joseph S (2005. )Interleukin 8 dimerization as a mechanism for regulation of neutrophil adherence-dependent oxidant production. Shock (Augusta, Ga.), ,23 (4 ),371-6

Okaya, T; Holthaus, R; Kato, A; Lentsch, A B (2004. )Involvement of the neuropeptide substance P in lung inflammation induced by hepatic ischemia/reperfusion.Inflammation research : official journal of the European Histamine Research Society ... [et al.], ,53 (6 ),257-61

Shen, Hui; Lentsch, Alex B (2004. )Progressive dysregulation of transcription factors NF-kappa B and STAT1 in prostate cancer cells causes proangiogenic production of CXC chemokines.American journal of physiology. Cell physiology, ,286 (4 ),C840-7

Okaya, Tomohisa; Lentsch, Alex B (2004. )Peroxisome proliferator-activated receptor-alpha regulates postischemic liver injury.American journal of physiology. Gastrointestinal and liver physiology, ,286 (4 ),G606-12

Umanskiy, Konstantin; Robinson, Chad; Cave, Cindy; Williams, Mark A; Lentsch, Alex B; Cuschieri, Joseph; Solomkin, Joseph S (2003. )NADPH oxidase activation in fibronectin adherent human neutrophils: A potential role for beta1 integrin ligation.Surgery, ,134 (2 ),378-83

Okaya, Tomohisa; Lentsch, Alex B Cytokine cascades and the hepatic inflammatory response to ischemia and reperfusion. Journal of investigative surgery : the official journal of the Academy of Surgical Research, ,16 (3 ),141-7

Kato, Atsushi; Okaya, Tomohisa; Lentsch, Alex B (2003. )Endogenous IL-13 protects hepatocytes and vascular endothelial cells during ischemia/reperfusion injury.Hepatology (Baltimore, Md.), ,37 (2 ),304-12

Schuschke, Dale A; Percival, Susan S; Lominadze, David; Saari, Jack T; Lentsch, Alex B (2002. )Tissue-specific ICAM-1 expression and neutrophil transmigration in the copper-deficient rat. Inflammation, ,26 (6 ),297-303

Kato, Atsushi; Gabay, Cem; Okaya, Tomohisa; Lentsch, Alex B (2002. )Specific role of interleukin-1 in hepatic neutrophil recruitment after ischemia/reperfusion.The American journal of pathology, ,161 (5 ),1797-803

Guo, Ren-Feng; Lentsch, Alex B; Sarma, J Vidya; Sun, Lei; Riedemann, Niels C; McClintock, Shannon D; McGuire, Stephanie R; Van Rooijen, Nico; Ward, Peter A (2002. )Activator protein-1 activation in acute lung injury.The American journal of pathology, ,161 (1 ),275-82

Lentsch, Alex B (2002. )The Duffy antigen/receptor for chemokines (DARC) and prostate cancer. A role as clear as black and white?.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, ,16 (9 ),1093-5

Kato, Atsushi; Edwards, Michael J; Lentsch, Alex B (2002. )Gene deletion of NF-kappa B p50 does not alter the hepatic inflammatory response to ischemia/reperfusion. Journal of hepatology, ,37 (1 ),48-55

Anaya-Prado, Roberto; Toledo-Pereyra, Luis H; Lentsch, Alex B; Ward, Peter A (2002. )Ischemia/reperfusion injury. The Journal of surgical research, ,105 (2 ),248-58

Ward, Peter A; Lentsch, Alex B Endogenous regulation of the acute inflammatory response. Molecular and cellular biochemistry, ,234-235 (1-2 ),225-8

Kato, Atsushi; Singh, Saurabh; McLeish, Kenneth R; Edwards, Michael J; Lentsch, Alex B (2002. )Mechanisms of hypothermic protection against ischemic liver injury in mice.American journal of physiology. Gastrointestinal and liver physiology, ,282 (4 ),G608-16

Lentsch, A B; Kato, A; Davis, B; Wang, W; Chao, C; Edwards, M J (2001. )STAT4 and STAT6 regulate systemic inflammation and protect against lethal endotoxemia.The Journal of clinical investigation, ,108 (10 ),1475-82

Lentsch, A B; Ward, P A (2001. )Regulation of experimental lung inflammation. Respiration physiology, ,128 (1 ),17-22

Lentsch, A B; Kato, A; Saari, J T; Schuschke, D A (2001. )Augmented metalloproteinase activity and acute lung injury in copper-deficient rats. American journal of physiology. Lung cellular and molecular physiology, ,281 (2 ),L387-93

Guo, R F; Lentsch, A B; Warner, R L; Huber-Lang, M; Sarma, J V; Hlaing, T; Shi, M M; Lukacs, N W; Ward, P A (2001. )Regulatory effects of eotaxin on acute lung inflammatory injury. Journal of immunology (Baltimore, Md. : 1950), ,166 (8 ),5208-18

Molestina, R E; Miller, R D; Lentsch, A B; Ramirez, J A; Summersgill, J T (2000. )Requirement for NF-kappaB in transcriptional activation of monocyte chemotactic protein 1 by Chlamydia pneumoniae in human endothelial cells. Infection and immunity, ,68 (7 ),4282-8

Kato, A; Yoshidome, H; Edwards, M J; Lentsch, A B (2000. )Reduced hepatic ischemia/reperfusion injury by IL-4: potential anti-inflammatory role of STAT6. Inflammation research : official journal of the European Histamine Research Society ... [et al.], ,49 (6 ),275-9

Mulligan, M S; Lentsch, A B; Huber-Lang, M; Guo, R F; Sarma, V; Wright, C D; Ulich, T R; Ward, P A (2000. )Anti-inflammatory effects of mutant forms of secretory leukocyte protease inhibitor.The American journal of pathology, ,156 (3 ),1033-9

Bless, N M; Huber-Lang, M; Guo, R F; Warner, R L; Schmal, H; Czermak, B J; Shanley, T P; Crouch, L D; Lentsch, A B; Sarma, V; Mulligan, M S; Friedl, H P; Ward, P A (2000. )Role of CC chemokines (macrophage inflammatory protein-1 beta, monocyte chemoattractant protein-1, RANTES) in acute lung injury in rats. Journal of immunology (Baltimore, Md. : 1950), ,164 (5 ),2650-9

Lentsch, A B; Ward, P A (2000. )Regulation of inflammatory vascular damage.The Journal of pathology, ,190 (3 ),343-8

Lentsch, A B; Ward, P A (2000. )The NFkappaBb/IkappaB system in acute inflammation. Archivum immunologiae et therapiae experimentalis, ,48 (2 ),59-63

Yoshidome, H; Kato, A; Miyazaki, M; Edwards, M J; Lentsch, A B (1999. )IL-13 activates STAT6 and inhibits liver injury induced by ischemia/reperfusion.The American journal of pathology, ,155 (4 ),1059-64

Lentsch, A B; Yoshidome, H; Warner, R L; Ward, P A; Edwards, M J (1999. )Secretory leukocyte protease inhibitor in mice regulates local and remote organ inflammatory injury induced by hepatic ischemia/reperfusion. Gastroenterology, ,117 (4 ),953-61

Lentsch, Alex B.; Ward, Peter A. (1999. )Understanding the Pathogenesis of Inflammation Using Rodent Models: Identification of a Transcription Factor (NFkappaB) Necessary for Development of Inflammatory Injury. ILAR journal / National Research Council, Institute of Laboratory Animal Resources, ,40 (4 ),151-156

Yoshidome, H; Kato, A; Edwards, M J; Lentsch, A B (1999. )Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: implications of a central role for nuclear factor kappaB.Hepatology (Baltimore, Md.), ,30 (1 ),203-8

Lentsch, A B; Crouch, L D; Jordan, J A; Czermak, B J; Yun, E C; Guo, R; Sarma, V; Diehl, K M; Ward, P A (1999. )Regulatory effects of interleukin-11 during acute lung inflammatory injury. Journal of leukocyte biology, ,66 (1 ),151-7

Ward, P A; Lentsch, A B (1999. )The acute inflammatory response and its regulation. Archives of surgery (Chicago, Ill. : 1960), ,134 (6 ),666-9

Czermak, B J; Lentsch, A B; Bless, N M; Schmal, H; Friedl, H P; Ward, P A (1999. )Synergistic enhancement of chemokine generation and lung injury by C5a or the membrane attack complex of complement.The American journal of pathology, ,154 (5 ),1513-24

Lentsch, A B; Czermak, B J; Jordan, J A; Ward, P A (1999. )Regulation of acute lung inflammatory injury by endogenous IL-13. Journal of immunology (Baltimore, Md. : 1950), ,162 (2 ),1071-6

Bless, N M; Warner, R L; Padgaonkar, V A; Lentsch, A B; Czermak, B J; Schmal, H; Friedl, H P; Ward, P A (1999. )Roles for C-X-C chemokines and C5a in lung injury after hindlimb ischemia-reperfusion. The American journal of physiology, ,276 (1 Pt 1 ),L57-63

Schmal, H; Czermak, B J; Lentsch, A B; Bless, N M; Beck-Schimmer, B; Friedl, H P; Ward, P A (1998. )Soluble ICAM-1 activates lung macrophages and enhances lung injury. Journal of immunology (Baltimore, Md. : 1950), ,161 (7 ),3685-93

Mulligan, M S; Lentsch, A B; Shanley, T P; Miyasaka, M; Johnson, K J; Ward, P A (1998. )Cytokine and adhesion molecule requirements for lung injury induced by anti-glomerular basement membrane antibody. Inflammation, ,22 (4 ),403-17

Mulligan, M S; Lentsch, A B; Miyasaka, M; Ward, P A (1998. )Cytokine and adhesion molecule requirements for neutrophil recruitment during glycogen-induced peritonitis. Inflammation research : official journal of the European Histamine Research Society ... [et al.], ,47 (6 ),251-5

Mulligan, M S; Lentsch, A B; Ward, P A (1998. )In vivo recruitment of neutrophils: consistent requirements for L-arginine and variable requirements for complement and adhesion molecules. Inflammation, ,22 (3 ),327-39

Lentsch, A B; Edwards, M J; Sims, D E; Miller, F N (1998. )N omega-nitro-L-arginine methyl ester inhibits inflammatory liver injury induced by interleukin-2. Journal of leukocyte biology, ,63 (1 ),22-30

Lentsch, A B; Miller, F N; Edwards, M J (1997. )Interleukin-2-induced hepatic injury involves temporal patterns of cell adhesion in the microcirculation. The American journal of physiology, ,272 (4 Pt 1 ),G727-31

Lentsch, A B; Nakagawa, K; Yoshidome, H; Gerassimides, A; Miller, F N; Edwards, M J (1997. )Distinct biological activities of recombinant forms of human interleukin-2 in vivo. Cancer immunology, immunotherapy : CII, ,43 (6 ),331-6

Lentsch, A B; Edwards, M J; Miller, F N (1996. )Interleukin-2 induces increased platelet-endothelium interactions: a potential mechanism of toxicity. The Journal of laboratory and clinical medicine, ,128 (1 ),75-82

Edwards, M J; Gable, D R; Lentsch, A B; Richardson, J D (1996. )The rationale for esophagectomy as the optimal therapy for Barrett's esophagus with high-grade dysplasia. Annals of surgery, ,223 (5 ),585-9; discussion 58

Anderson, J A; Lentsch, A B; Hadjiminas, D J; Miller, F N; Martin, A W; Nakagawa, K; Edwards, M J (1996. )The role of cytokines, adhesion molecules, and chemokines in interleukin-2-induced lymphocytic infiltration in C57BL/6 mice.The Journal of clinical investigation, ,97 (8 ),1952-9

Chatterjee, Tapan K; Basford, Joshua E; Knoll, Ellen; Tong, Wilson S; Blanco, Victor; Blomkalns, Andra L; Rudich, Steven; Lentsch, Alex B; Hui, David Y; Weintraub, Neal L (2014. )HDAC9 knockout mice are protected from adipose tissue dysfunction and systemic metabolic disease during high-fat feeding.Diabetes, ,63 (1 ),176-87

Yang, Sung H; Gangidine, Matt; Pritts, Timothy A; Goodman, Michael D; Lentsch, Alex B (2013. )Interleukin 6 mediates neuroinflammation and motor coordination deficits after mild traumatic brain injury and brief hypoxia in mice.Shock (Augusta, Ga.), ,40 (6 ),471-5

Ziobro, Regan; Henry, Brian; Edwards, Michael J; Lentsch, Alex B; Gulbins, Erich (2013. )Ceramide mediates lung fibrosis in cystic fibrosis.Biochemical and biophysical research communications, ,434 (4 ),705-9

Makley, Amy T; Belizaire, Ritha; Campion, Eric M; Goodman, Michael D; Sonnier, Dennis I; Friend, Lou Ann; Schuster, Rebecca M; Bailey, Stephanie R; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A (2012. )Simulated aeromedical evacuation does not affect systemic inflammation or organ injury in a murine model of hemorrhagic shock. Military medicine, ,177 (8 ),911-6

Earnest, Ryan E; Sonnier, Dennis I; Makley, Amy T; Campion, Eric M; Wenke, Joseph C; Bailey, Stephanie R; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A (2012. )Supplemental oxygen attenuates the increase in wound bacterial growth during simulated aeromedical evacuation in goats.The journal of trauma and acute care surgery, ,73 (1 ),80-6

Makley, Amy T; Goodman, Michael D; Belizaire, Ritha M; Friend, Lou Ann W; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A (2012. )Damage control resuscitation decreases systemic inflammation after hemorrhage.The Journal of surgical research, ,175 (2 ),e75-82

Thobe, M N; Gray, J K; Gurusamy, D; Paluch, A M; Wagh, P K; Pathrose, P; Lentsch, A B; Waltz, S E (2011. )The Ron receptor promotes prostate tumor growth in the TRAMP mouse model.Oncogene, ,30 (50 ),4990-8

Sakai, N; Kuboki, S; Van Sweringen, H L; Tevar, A D; Schuster, R; Blanchard, J; Edwards, M J; Lentsch, A B (2011. )CXCR1 deficiency does not alter liver regeneration after partial hepatectomy in mice.Transplantation proceedings, ,43 (5 ),1967-70

Elson, Joshua K; Beebe-Dimmer, Jennifer L; Morgenstern, Hal; Chilkuri, Mahdavi; Blanchard, John; Lentsch, Alex B (2011. )The Duffy Antigen/Receptor for Chemokines (DARC) and prostate-cancer risk among Jamaican men.Journal of immigrant and minority health / Center for Minority Public Health, ,13 (1 ),36-41

Makley, Amy T; Goodman, Michael D; Friend, Lou Ann W; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A (2010. )Murine blood banking: characterization and comparisons to human blood.Shock (Augusta, Ga.), ,34 (1 ),40-5

Makley, Amy T; Goodman, Michael D; Friend, Lou Ann W; Deters, Joseph S; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A (2010. )Resuscitation with fresh whole blood ameliorates the inflammatory response after hemorrhagic shock.The Journal of trauma, ,68 (2 ),305-11

Kuboki, Satoshi; Sakai, Nozomu; Clarke, Callisia; Schuster, Rebecca; Blanchard, John; Edwards, Michael J; Lentsch, Alex B (2009. )The peptidyl-prolyl isomerase, Pin1, facilitates NF-kappaB binding in hepatocytes and protects against hepatic ischemia/reperfusion injury.Journal of hepatology, ,51 (2 ),296-306

Tschöp, Johannes; Kasten, Kevin R; Nogueiras, Ruben; Goetzman, Holly S; Cave, Cynthia M; England, Lisa G; Dattilo, Jonathan; Lentsch, Alex B; Tschöp, Matthias H; Caldwell, Charles C (2009. )The cannabinoid receptor 2 is critical for the host response to sepsis.Journal of immunology (Baltimore, Md. : 1950), ,183 (1 ),499-505

Kuboki, Satoshi; Sakai, Nozomu; Tschöp, Johannes; Edwards, Michael J; Lentsch, Alex B; Caldwell, Charles C (2009. )Distinct contributions of CD4+ T cell subsets in hepatic ischemia/reperfusion injury.American journal of physiology. Gastrointestinal and liver physiology, ,296 (5 ),G1054-9

Zahedi, Kamyar; Lentsch, Alex B; Okaya, Tomohisa; Barone, Sharon; Sakai, Nozomu; Witte, David P; Arend, Lois J; Alhonen, Leena; Jell, Jason; Jänne, Juhani; Porter, Carl W; Soleimani, Manoocher (2009. )Spermidine/spermine-N1-acetyltransferase ablation protects against liver and kidney ischemia-reperfusion injury in mice.American journal of physiology. Gastrointestinal and liver physiology, ,296 (4 ),G899-909

Galloway, Elizabeth; Shin, Thomas; Huber, Nadine; Eismann, Thorsten; Kuboki, Satoshi; Schuster, Rebecca; Blanchard, John; Wong, Hector R; Lentsch, Alex B (2008. )Activation of hepatocytes by extracellular heat shock protein 72.American journal of physiology. Cell physiology, ,295 (2 ),C514-20

Shin, Thomas; Kuboki, Satoshi; Huber, Nadine; Eismann, Thorsten; Galloway, Elizabeth; Schuster, Rebecca; Blanchard, John; Pritts, Timothy A; Lentsch, Alex B (2008. )Activation of peroxisome proliferator-activated receptor-gamma during hepatic ischemia is age-dependent.The Journal of surgical research, ,147 (2 ),200-5

Martignoni, André; Tschöp, Johannes; Goetzman, Holly S; Choi, Lisa G; Reid, Maria D; Johannigman, Jay A; Lentsch, Alex B; Caldwell, Charles C (2008. )CD4-expressing cells are early mediators of the innate immune system during sepsis.Shock (Augusta, Ga.), ,29 (5 ),591-7

Thiel, Manfred; Caldwell, Charles C; Kreth, Simone; Kuboki, Satoshi; Chen, P; Smith, Patrick; Ohta, Akio; Lentsch, Alex B; Lukashev, Dmitry; Sitkovsky, Michail V (2007. )Targeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival.PloS one, ,2 (9 ),e853

Saari, Jack T; Wold, Loren E; Duan, Jinhong; Ren, Jun; Carlson, Hanqian L; Bode, Ann M; Lentsch, Alex B; Zeng, Huawei; Schuschke, Dale A (2007. )Cardiac nitric oxide synthases are elevated in dietary copper deficiency.The Journal of nutritional biochemistry, ,18 (7 ),443-8

Solomkin, Joseph S; Robinson, Chad T; Cave, Cynthia M; Umanskiy, Konstantin; Matlin, Karl; Williams, Mark A; Lentsch, Alex B (2006. )Formation of focal adhesion-like structures in circulating human neutrophils after severe injury: triggering of a tissue-phase response in the vascular space.Shock (Augusta, Ga.), ,25 (5 ),440-5

Mallakin, Ali; Kutcher, Louis W; McDowell, Susan A; Kong, Sue; Schuster, Rebecca; Lentsch, Alex B; Aronow, Bruce J; Leikauf, George D; Waltz, Susan E (2006. )Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury.American journal of respiratory cell and molecular biology, ,34 (1 ),15-27

Shen, Hui; Schuster, Rebecca; Stringer, Keith F; Waltz, Susan E; Lentsch, Alex B (2006. )The Duffy antigen/receptor for chemokines (DARC) regulates prostate tumor growth.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, ,20 (1 ),59-64

Caldwell, Charles C; Okaya, Tomohisa; Martignoni, Andre; Husted, Thomas; Schuster, Rebecca; Lentsch, Alex B (2005. )Divergent functions of CD4+ T lymphocytes in acute liver inflammation and injury after ischemia-reperfusion.American journal of physiology. Gastrointestinal and liver physiology, ,289 (5 ),G969-76

Barone, Sharon; Okaya, Tomohisa; Rudich, Steve; Petrovic, Snezana; Tenrani, Kathy; Wang, Zhaohui; Zahedi, Kamyar; Casero, Robert A; Lentsch, Alex B; Soleimani, Manoocher (2005. )Distinct and sequential upregulation of genes regulating cell growth and cell cycle progression during hepatic ischemia-reperfusion injury.American journal of physiology. Cell physiology, ,289 (4 ),C826-35

Lentsch, Alex B (2005. )Activation and function of hepatocyte NF-kappaB in postischemic liver injury.Hepatology (Baltimore, Md.), ,42 (1 ),216-8

Husted, Thomas L; Lentsch, Alex B (2005. )Anti-inflammatory approaches to the prevention of ischemia/reperfusion injury in solid organ transplantation. Current opinion in investigational drugs (London, England : 2000), ,6 (5 ),508-12

Kato, Atsushi; Graul-Layman, Amanda; Edwards, Michael J; Lentsch, Alex B (2002. )Promotion of hepatic ischemia/reperfusion injury by IL-12 is independent of STAT4. Transplantation, ,73 (7 ),1142-5

Godshall, C J; Lentsch, A B; Peyton, J C; Scott, M J; Cheadle, W G (2001. )STAT4 is required for antibacterial defense but enhances mortality during polymicrobial sepsis.Clinical and diagnostic laboratory immunology, ,8 (6 ),1044-8

Dawson, T C; Lentsch, A B; Wang, Z; Cowhig, J E; Rot, A; Maeda, N; Peiper, S C (2000. )Exaggerated response to endotoxin in mice lacking the Duffy antigen/receptor for chemokines (DARC). Blood, ,96 (5 ),1681-4

Lentsch, A B; Kato, A; Yoshidome, H; McMasters, K M; Edwards, M J (2000. )Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury.Hepatology (Baltimore, Md.), ,32 (2 ),169-73

Kato, A; Yoshidome, H; Edwards, M J; Lentsch, A B (2000. )Regulation of liver inflammatory injury by signal transducer and activator of transcription-6.The American journal of pathology, ,157 (1 ),297-302

Yoshidome, H; Miyazaki, M; Shimizu, H; Ito, H; Nakagawa, K; Ambiru, S; Nakajima, N; Edwards, M J; Lentsch, A B (2000. )Obstructive jaundice impairs hepatic sinusoidal endothelial cell function and renders liver susceptible to hepatic ischemia/reperfusion. Journal of hepatology, ,33 (1 ),59-67

Lentsch, A B; Yoshidome, H; Kato, A; Warner, R L; Cheadle, W G; Ward, P A; Edwards, M J (1999. )Requirement for interleukin-12 in the pathogenesis of warm hepatic ischemia/reperfusion injury in mice.Hepatology (Baltimore, Md.), ,30 (6 ),1448-53

Yoshidome, H; Kato, A; Edwards, M J; Lentsch, A B (1999. )Interleukin-10 inhibits pulmonary NF-kappaB activation and lung injury induced by hepatic ischemia-reperfusion. The American journal of physiology, ,277 (5 Pt 1 ),L919-23

Lentsch, A B; Czermak, B J; Bless, N M; Van Rooijen, N; Ward, P A (1999. )Essential role of alveolar macrophages in intrapulmonary activation of NF-kappaB.American journal of respiratory cell and molecular biology, ,20 (4 ),692-8

Lentsch, A B; Ward, P A (1999. )Activation and regulation of NFkappaB during acute inflammation.Clinical chemistry and laboratory medicine : CCLM / FESCC, ,37 (3 ),205-8

Lentsch, A B; Miller, F N; Edwards, M J (1999. )Mechanisms of leukocyte-mediated tissue injury induced by interleukin-2. Cancer immunology, immunotherapy : CII, ,47 (5 ),243-8

Yoshidome, H; Lentsch, A B; Cheadle, W G; Miller, F N; Edwards, M J (1999. )Enhanced pulmonary expression of CXC chemokines during hepatic ischemia/reperfusion-induced lung injury in mice.The Journal of surgical research, ,81 (1 ),33-7

Bless, N M; Tojo, S J; Kawarai, H; Natsume, Y; Lentsch, A B; Padgaonkar, V A; Czermak, B J; Schmal, H; Friedl, H P; Ward, P A (1998. )Differing patterns of P-selectin expression in lung injury.The American journal of pathology, ,153 (4 ),1113-22

Czermak, B J; Lentsch, A B; Bless, N M; Schmal, H; Friedl, H P; Ward, P A (1998. )Role of complement in in vitro and in vivo lung inflammatory reactions. Journal of leukocyte biology, ,64 (1 ),40-8

Lentsch, A B; Czermak, B J; Bless, N M; Ward, P A (1998. )NF-kappaB activation during IgG immune complex-induced lung injury: requirements for TNF-alpha and IL-1beta but not complement. The American journal of pathology, ,152 (5 ),1327-36

Lentsch, A B; Yoshidome, H; Cheadle, W G; Miller, F N; Edwards, M J (1998. )Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and KC.Hepatology (Baltimore, Md.), ,27 (4 ),1172-7

Lentsch, A B; Yoshidome, H; Cheadle, W G; Miller, F N; Edwards, M J (1998. )Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and Kupffer cells.Hepatology (Baltimore, Md.), ,27 (2 ),507-12

Lentsch, A B; Shanley, T P; Sarma, V; Ward, P A (1997. )In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13.The Journal of clinical investigation, ,100 (10 ),2443-8

Lentsch, A B; Edwards, M J; Sims, D E; Nakagawa, K; Wellhausen, S R; Miller, F N (1996. )Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce toxicity in C3H/HeN mice. Journal of leukocyte biology, ,60 (1 ),51-7

Nakagawa, K; Miller, F N; Sims, D E; Lentsch, A B; Miyazaki, M; Edwards, M J (1996. )Mechanisms of interleukin-2-induced hepatic toxicity. Cancer research, ,56 (3 ),507-10

Lindberg, R A; Slaaf, D W; Lentsch, A B; Miller, F N (1994. )Involvement of nitric oxide and cyclooxygenase products in photoactivation-induced microvascular occlusion.Microvascular research, ,47 (2 ),203-21

Quillin, Ralph C; Wilson, Gregory C; Nojima, Hiroyuki; Freeman, Christopher H; Wang, Jiang; Schuster, Rebecca M; Blanchard, John A; Edwards, Michael J; Gandhi, Chandrashekhar R; Gulbins, Erich; Lentsch, Alex B (2014. )Inhibition of Acidic Sphingomyelinase Reduces Established Hepatic Fibrosis in Mice.Hepatology research : the official journal of the Japan Society of Hepatology, ,

Nojima, Hiroyuki; Freeman, Christopher M; Gulbins, Erich; Lentsch, Alex B (2015. )Sphingolipids in liver injury, repair and regeneration.Biological chemistry, ,396 (6-7 ),633-43

Wilson, Gregory C; Freeman, Christopher M; Kuethe, Joshua W; Quillin, Ralph C; Nojima, Hiroyuki; Schuster, Rebecca; Blanchard, John; Edwards, Michael J; Caldwell, Charles C; Lentsch, Alex B (2015. )CXC chemokine receptor-4 signaling limits hepatocyte proliferation after hepatic ischemia-reperfusion in mice.American journal of physiology. Gastrointestinal and liver physiology, ,308 (8 ),G702-9

Jin, Shunying; Merchant, Michael L; Ritzenthaler, Jeffrey D; McLeish, Kenneth R; Lederer, Eleanor D; Torres-Gonzalez, Edilson; Fraig, Mostafa; Barati, Michelle T; Lentsch, Alex B; Roman, Jesse; Klein, Jon B; Rane, Madhavi J (2015. )Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators.PloS one, ,10 (4 ),e0121637

Wilson, Gregory C; Kuboki, Satoshi; Freeman, Christopher M; Nojima, Hiroyuki; Schuster, Rebecca M; Edwards, Michael J; Lentsch, Alex B (2015. )CXC chemokines function as a rheostat for hepatocyte proliferation and liver regeneration.PloS one, ,10 (3 ),e0120092

Richter, Jillian R; Sutton, Jeffrey M; Belizaire, Ritha M; Friend, Lou Ann; Schuster, Rebecca M; Johannigman, Taylor A; Miller, Steven G; Lentsch, Alex B; Pritts, Timothy A (2014. )Macrophage-derived chemokine (CCL22) is a novel mediator of lung inflammation following hemorrhage and resuscitation.Shock (Augusta, Ga.), ,42 (6 ),525-31

Yang, Sung; Stepien, David; Hanseman, Dennis; Robinson, Bryce; Goodman, Michael D; Pritts, Timothy A; Caldwell, Charles C; Remick, Daniel G; Lentsch, Alex B (2014. )Substance P mediates reduced pneumonia rates after traumatic brain injury.Critical care medicine, ,42 (9 ),2092-100

Pewzner-Jung, Yael; Tavakoli Tabazavareh, Shaghayegh; Grassmé, Heike; Becker, Katrin Anne; Japtok, Lukasz; Steinmann, Jörg; Joseph, Tammar; Lang, Stephan; Tuemmler, Burkhard; Schuchman, Edward H; Lentsch, Alex B; Kleuser, Burkhard; Edwards, Michael J; Futerman, Anthony H; Gulbins, Erich (2014. )Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa.EMBO molecular medicine, ,6 (9 ),1205-14

Freeman, Christopher M; Quillin, Ralph C; Wilson, Gregory C; Nojima, Hiroyuki; Johnson, Bobby L; Sutton, Jeffrey M; Schuster, Rebecca M; Blanchard, John; Edwards, Michael J; Caldwell, Charles C; Lentsch, Alex B (2014. )Characterization of microparticles after hepatic ischemia-reperfusion injury.PloS one, ,9 (5 ),e97945

Hoehn, Richard S; Jernigan, Peter L; Japtok, Lukasz; Chang, Alex L; Midura, Emily F; Caldwell, Charles C; Kleuser, Burkhard; Lentsch, Alex B; Edwards, Michael J; Gulbins, Erich; Pritts, Timothy A (2016. )Acid Sphingomyelinase Inhibition in Stored Erythrocytes Reduces Transfusion-Associated Lung Inflammation.Annals of surgery, ,

Nojima, Hiroyuki; Freeman, Christopher M; Schuster, Rebecca M; Japtok, Lukasz; Kleuser, Burkhard; Edwards, Michael J; Gulbins, Erich; Lentsch, Alex B (2016. )Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate.Journal of hepatology, ,64 (1 ),60-8

Chang, Alex L; Kim, Young; Seitz, Aaron P; Schuster, Rebecca M; Lentsch, Alex B; Pritts, Timothy A (2017. )Erythrocyte-Derived Microparticles Activate Pulmonary Endothelial Cells in a Murine Model of Transfusion.Shock (Augusta, Ga.), ,47 (5 ),632-637

Hoehn, Richard S; Jernigan, Peter L; Japtok, Lukasz; Chang, Alex L; Midura, Emily F; Caldwell, Charles C; Kleuser, Burkhard; Lentsch, Alex B; Edwards, Michael J; Gulbins, Erich; Pritts, Timothy A (2017. )Acid Sphingomyelinase Inhibition in Stored Erythrocytes Reduces Transfusion-Associated Lung Inflammation.Annals of surgery, ,265 (1 ),218-226

Nojima, Hiroyuki; Konishi, Takanori; Freeman, Christopher M; Schuster, Rebecca M; Japtok, Lukasz; Kleuser, Burkhard; Edwards, Michael J; Gulbins, Erich; Lentsch, Alex B (2016. )Chemokine Receptors, CXCR1 and CXCR2, Differentially Regulate Exosome Release in Hepatocytes.PloS one, ,11 (8 ),e0161443

Caldwell C.C.; Goetzman H.S.; Konishi T.; Lentsch A.B.; Schuster R.M. (03-01-2020. )Fibrotic liver has prompt recovery after ischemia-reperfusion injury.American journal of physiology. Gastrointestinal and liver physiology, ,318 (3 ),G390-G400

Abplanalp W.; Caldwell C.; Goodman M.; Jung A.; Kim Y.; Lentsch A.; Pritts T.; Schuster R. (01-01-2020. )Microparticles from aged packed red blood cell units stimulate pulmonary microthrombus formation via.Thrombosis Research, ,185 ,160-166

Konishi T.; Lentsch A.; Schuster R. (03-01-2019. )Liver repair and regeneration after ischemia-reperfusion injury is associated with prolonged fibrosi.American Journal of Physiology - Gastrointestinal and Liver Physiology, ,316 (3 ),G323-G331

Caldwell C.; Goetzman H.; Konishi T.; Lentsch A.; Schuster R. (01-01-2019. )Cell-specific regulatory effects of CXCR2 on cholestatic liver injury.American Journal of Physiology - Gastrointestinal and Liver Physiology, ,317 (6 ),G773-G783

Konishi T.; Lentsch A. (10-01-2018. )Changes in arachidonic acid metabolism during liver ischemia triggers induction of inflammatory inju.Hepatology, ,68 (4 ),1642-1643

Konishi T.; Lentsch A.; Schuster R. (04-01-2018. )Proliferation of hepatic stellate cells, mediated by YAP and TAZ, contributes to liver repair and re.American Journal of Physiology - Gastrointestinal and Liver Physiology, ,314 (4 ),G471-G482

Hexley P.; Johannigman T.; Lentsch A.; Pritts T.; Richter J.; Sutton J. (03-01-2018. )Leukoreduction of packed red blood cells attenuates proinflammatory properties of storage-derived mi.Journal of Surgical Research, ,223 ,128-135

Abplanalp W.; Caldwell C.; Gulbins E.; Jung A.; Kim Y.; Lentsch A.; Pritts T.; Schuster R. (03-01-2018. )Endocytosis of red blood cell microparticles by pulmonary endothelial cells is mediated by Rab5.Shock, ,49 (3 ),288-294

Konishi T.; Lentsch A. (01-01-2017. )Hepatic ischemia/reperfusion: Mechanisms of tissue injury, repair, and regeneration.Gene Expression, ,17 (4 ),277-287

Freeman C.; Lentsch A.; Nojima H.; Wilson G. (09-28-2015. )CXC chemokine receptor signaling in liver repair and regeneration.Signaling Pathways in Liver Diseases: Third Edition, ,166-173

Freeman C.; Lentsch A.; Nojima H.; Wilson G. (01-01-2015. )Role of CXC Chemokines in Liver Repair and Regeneration.Liver Regeneration: Basic Mechanisms, Relevant Models and Clinical Applications, ,113-123

Blanchard J.; Edwards M.; Freeman C.; Gandhi C.; Gulbins E.; Lentsch A.; Nojima H.; Quillin R.; Schuster R.; Wang J.; Wilson G. (01-01-2015. )Inhibition of acidic sphingomyelinase reduces established hepatic fibrosis in mice.Hepatology Research, ,45 (3 ),305-314

Basford J.E.; Blanco V.; Blomkalns A.L.; Chatterjee T.K.; Hui D.Y.; Knoll E.; Lentsch A.B.; Rudich S.; Tong W.S.; Weintraub N.L. (01-01-2014. )HDAC9 knockout mice are protected from adipose tissue dysfunction and systemic metabolic disease dur.Diabetes, ,63 (1 ),176-187

Edwards M.; Gulbins E.; Henry B.; Lentsch A.; Riethmüller J.; Ziobro R. (12-01-2013. )Ceramide in cystic fibrosis.Clinical Lipidology, ,8 (6 ),681-691

Belizaire R.; Blanchard J.; Burns J.; Edwards M.; Lentsch A.; Quillin R.; Sakai N.; Schuster R.; Tevar A.; Van Sweringen H. (01-01-2012. )Interleukin-37 reduces liver inflammatory injury via effects on hepatocytes and non-parenchymal cell.Journal of Gastroenterology and Hepatology (Australia), ,27 (10 ),1609-1616

Denenberg A.; Hake P.; Lentsch A.; O'Connor M.; Piraino G.; Solan P.; Zingarelli B. (04-01-2011. )Liver X receptor ? activation with the synthetic ligand T0901317 reduces lung injury and inflammatio.Shock, ,35 (4 ),367-374

Day D.; Flierl M.; Huber-Lang M.; Lentsch A.; Nadeau B.; Rittirsch D.; Sarma J.; Ward P. (02-12-2009. )Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response.PLoS ONE, ,4 (2 ),

Kuboki S.; Lentsch A.; Shin T. (05-01-2008. )Roles of nuclear factor-?B in postischemic liver.Hepatology Research, ,38 (5 ),429-440

Barone S.; Bevans S.; Burnham C.; Lentsch A.; Rabb H.; Revelo M.; Soleimani M.; Thakar C.; Wang Z.; Zahedi K. (02-01-2006. )Erratum: Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney isc .Journal of Clinical Investigation, ,116 (2 ),549

Lentsch A. (07-01-2005. )Activation and function of hepatocyte NF-?B in postischemic liver injury.Hepatology, ,42 (1 ),216-218

Lentsch A. (01-01-2003. )Proteomics in Practice: A Laboratory Manual of Proteome Analysis.Journal of Investigative Surgery, ,16 (5 ),305

Lentsch A. (12-01-2000. )Regulation of acute inflammation by the duffy antigen/ receptor for chemokines (darc): exaggerated r .Blood, ,96 (11 PART I ),

Lentsch A.; Ward P. (01-01-1999. )Understanding the pathogenesis of inflammation using rodent models: Identification of a transcriptio.ILAR Journal, ,40 (4 ),151-156

Bless N.; Czermak B.; Lentsch A.; Ward P. (03-20-1998. )Determinants of NF-?B activation in acute lung injury .FASEB Journal, ,12 (5 ),

Lentsch A.; Shanley T.; Ward P. (12-01-1997. )Interleukin-10 protects against IgG immune complex-induced lung injury through suppression of NF-?B .FASEB Journal, ,11 (3 ),

Crouch L.; Johnson K.; Lentsch A.; Ward P.; Warner R. (12-01-1997. )Regulatory effects of adrenal gland products in IgG immune complex acute lung injury .FASEB Journal, ,11 (3 ),

Edwards M.; Lentsch A.; Miller F.; Nakagawa K.; Sims D. (12-01-1996. )Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce t .FASEB Journal, ,10 (3 ),

Lentsch A.; Lindberg R.; Miller F.; Slaaf D. (01-01-1994. )Involvement of nitric oxide and cyclooxygenase products in photoactivation-induced microvascular occ.Microvascular Research, ,47 (2 ),203-221

Keywords

inflammation, sepsis, trauma, liver injury, cytokines, leukocytes

Other Information

Division of Research,

Contact Information

Academic - CARE/Crawley Building
Room E870
Cincinnati  Ohio, 45267
Phone: 513-558-0175
Fax: 513-558-3513
alex.lentsch@uc.edu