Diana M. Lindquist , PhD

Peer Reviewed Publications

Yang, Dianer; Sun, Yu-Yo; Lin, Xiaoyi; Baumann, Jessica M; Dunn, R Scott; Lindquist, Diana M; Kuan, Chia-Yi (2013. ) Intranasal delivery of cell-penetrating anti-NF-?B peptides (Tat-NBD) alleviates infection-sensitized hypoxic-ischemic brain injury.Experimental neurology, , 247 ,447-55 More Information

Komoroski, Richard A; Lindquist, Diana M; Pearce, John M (2013. ) Lithium compartmentation in brain by 7Li MRS: effect of total lithium concentration.NMR in biomedicine, , 26 (9 ) ,1152-7 More Information

Yang, Dianer; Baumann, Jessica M; Sun, Yu-Yo; Tang, Mianzhi; Dunn, Richard Scott; Akeson, Ann L; Kernie, Steven G; Kallapur, Suhas; Lindquist, Diana M; Huang, Eric J; Potter, Stanley Steven; Liang, Hung-Chi; Kuan, Chia-Yi (2013. ) Overexpression of vascular endothelial growth factor in the germinal matrix induces neurovascular proteases and intraventricular hemorrhage.Science translational medicine, , 5 (193 ) ,193ra90 More Information

Kim, Hee Kyung; Lindquist, Diana M; Serai, Suraj D; Mariappan, Yogesh K; Wang, Lily L; Merrow, Arnold C; McGee, Kiaran P; Ehman, Richard L; Laor, Tal (2013. ) Magnetic resonance imaging of pediatric muscular disorders: recent advances and clinical applications.Radiologic clinics of North America, , 51 (4 ) ,721-42 More Information

Yang, Dianer; Sun, Yu-Yo; Nemkul, Niza; Baumann, Jessica M; Shereen, Ahmed; Dunn, R Scott; Wills-Karp, Marsha; Lawrence, Daniel A; Lindquist, Diana M; Kuan, Chia-Yi (2013. ) Plasminogen activator inhibitor-1 mitigates brain injury in a rat model of infection-sensitized neonatal hypoxia-ischemia.Cerebral cortex (New York, N.Y. : 1991), , 23 (5 ) ,1218-29 More Information

Kurosawa, Yuko; Degrauw, Ton J; Lindquist, Diana M; Blanco, Victor M; Pyne-Geithman, Gail J; Daikoku, Takiko; Chambers, James B; Benoit, Stephen C; Clark, Joseph F (2012. ) Cyclocreatine treatment improves cognition in mice with creatine transporter deficiency.The Journal of clinical investigation, , 122 (8 ) ,2837-46 More Information

Bhutta, Adnan T; Schmitz, Michael L; Swearingen, Christopher; James, Laura P; Wardbegnoche, Wendy L; Lindquist, Diana M; Glasier, Charles M; Tuzcu, Volkan; Prodhan, Parthak; Dyamenahalli, Umesh; Imamura, Michiaki; Jaquiss, Robert D B; Anand, Kanwaljeet J S (2012. ) Ketamine as a neuroprotective and anti-inflammatory agent in children undergoing surgery on cardiopulmonary bypass: a pilot randomized, double-blind, placebo-controlled trial.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, , 13 (3 ) ,328-37 More Information

Yuan, Weihong; McAllister, James P; Lindquist, Diana M; Gill, Nicholas; Holland, Scott K; Henkel, David; Rajagopal, Akila; Mangano, Francesco T (2012. ) Diffusion tensor imaging of white matter injury in a rat model of infantile hydrocephalus.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, , 28 (1 ) ,47-54 More Information

Pirko, Istvan; Cardin, Rhonda; Chen, Yi; Lohrey, Anne K; Lindquist, Diana M; Dunn, R Scott; Zivadinov, Robert; Johnson, Aaron J (2012. ) CMV infection attenuates the disease course in a murine model of multiple sclerosis.PloS one, , 7 (2 ) ,e32767 More Information

Pirko, Istvan; Chen, Yi; Lohrey, Anne K; McDole, Jeremiah; Gamez, Jeffrey D; Allen, Kathleen S; Pavelko, Kevin D; Lindquist, Diana M; Dunn, R Scott; Macura, Slobodan I; Johnson, Aaron J (2012. ) Contrasting roles for CD4 vs. CD8 T-cells in a murine model of virally induced "T1 black hole" formation.PloS one, , 7 (2 ) ,e31459 More Information

Lindquist, Diana M; Dunn, R Scott; Cecil, Kim M (2011. ) Long term antipsychotic treatment does not alter metabolite concentrations in rat striatum: an in vivo magnetic resonance spectroscopy study.Schizophrenia research, , 128 (1-3 ) ,83-90 More Information

Shereen, Ahmed; Nemkul, Niza; Yang, Dianer; Adhami, Faisal; Dunn, R Scott; Hazen, Missy L; Nakafuku, Masato; Ning, Gang; Lindquist, Diana M; Kuan, Chia-Yi (2011. ) Ex vivo diffusion tensor imaging and neuropathological correlation in a murine model of hypoxia-ischemia-induced thrombotic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , 31 (4 ) ,1155-69 More Information

Cecil, Kim M; Dietrich, Kim N; Altaye, Mekibib; Egelhoff, John C; Lindquist, Diana M; Brubaker, Christopher J; Lanphear, Bruce P (2011. ) Proton magnetic resonance spectroscopy in adults with childhood lead exposure.Environmental health perspectives, , 119 (3 ) ,403-8 More Information

Pirko, I; Johnson, A J; Chen, Yi; Lindquist, D M; Lohrey, A K; Ying, J; Dunn, R Scott (2011. ) Brain atrophy correlates with functional outcome in a murine model of multiple sclerosis.NeuroImage, , 54 (2 ) ,802-6 More Information

Yuan, Weihong; Deren, Kelley E; McAllister, James P; Holland, Scott K; Lindquist, Diana M; Cancelliere, Alessandro; Mason, Melissa; Shereen, Ahmed; Hertzler, Dean A; Altaye, Mekibib; Mangano, Francesco T (2010. ) Diffusion tensor imaging correlates with cytopathology in a rat model of neonatal hydrocephalus.Cerebrospinal fluid research, , 7 ,19 More Information

Brubaker, Christopher J; Schmithorst, Vincent J; Haynes, Erin N; Dietrich, Kim N; Egelhoff, John C; Lindquist, Diana M; Lanphear, Bruce P; Cecil, Kim M (2009. ) Altered myelination and axonal integrity in adults with childhood lead exposure: a diffusion tensor imaging study.Neurotoxicology, , 30 (6 ) ,867-75 More Information

McNamara, Robert K; Able, Jessica; Jandacek, Ronald; Rider, Therese; Tso, Patrick; Lindquist, Diana M (2009. ) Perinatal n-3 fatty acid deficiency selectively reduces myo-inositol levels in the adult rat PFC: an in vivo (1)H-MRS study.Journal of lipid research, , 50 (3 ) ,405-11 More Information

Bickel, Warren K; Miller, Michelle L; Yi, Richard; Kowal, Benjamin P; Lindquist, Diana M; Pitcock, Jeffery A (2007. ) Behavioral and neuroeconomics of drug addiction: competing neural systems and temporal discounting processes.Drug and alcohol dependence, , 90 Suppl 1 ,S85-91 More Information

Freeman, Thomas; Kimbrell, Tim; Booe, Leroy; Myers, Michael; Cardwell, David; Lindquist, Diana M; Hart, John; Komoroski, Richard A (2006. ) Evidence of resilience: neuroimaging in former prisoners of war.Psychiatry research, , 146 (1 ) ,59-64 More Information

Tesch, P A; Ekberg, A; Lindquist, D M; Trieschmann, J T (2004. ) Muscle hypertrophy following 5-week resistance training using a non-gravity-dependent exercise system.Acta physiologica Scandinavica, , 180 (1 ) ,89-98 More Information

Lambert, Charles P; Sullivan, Dennis H; Freeling, Scott A; Lindquist, Diana M; Evans, William J (2002. ) Effects of testosterone replacement and/or resistance exercise on the composition of megestrol acetate stimulated weight gain in elderly men: a randomized controlled trial. The Journal of clinical endocrinology and metabolism, , 87 (5 ) ,2100-6

Trappe, T A; Lindquist, D M; Carrithers, J A (2001. ) Muscle-specific atrophy of the quadriceps femoris with aging. Journal of applied physiology (Bethesda, Md. : 1985), , 90 (6 ) ,2070-4

Lindquist, D M; Dachtler, M; Hawk, R M; Karson, C N; Albert, K; Komoroski, R A (2000. ) Contribution of trifluoperazine metabolites to the in vivo (19)F NMR spectrum of rat brain. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, , 43 (5 ) ,756-9

Lindquist, D M; Hawk, R M; Karson, C N; Komoroski, R A (2000. ) Effects of antipsychotic drugs on metabolite ratios in rat brain in vivo. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, , 43 (3 ) ,355-8

Lindquist, Diana M; Beckwith, Travis; Cecil, Kim M; Sánchez-Martín, Francisco Javier; Landero-Figueroa, Julio; Puga, Alvaro (2015. ) Prenatal and early postnatal lead exposure in mice: neuroimaging findings.Quantitative imaging in medicine and surgery, , 5 (4 ) ,511-8 More Information

Sánchez-Martín, Francisco Javier; Lindquist, Diana M; Landero-Figueroa, Julio; Zhang, Xiang; Chen, Jing; Cecil, Kim M; Medvedovic, Mario; Puga, Alvaro (2015. ) Sex- and tissue-specific methylome changes in brains of mice perinatally exposed to lead.Neurotoxicology, , 46 ,92-100 More Information

Yang, Dianer; Sun, Yu-Yo; Bhaumik, Siddhartha Kumar; Li, Yikun; Baumann, Jessica M; Lin, Xiaoyi; Zhang, Yujin; Lin, Shang-Hsuan; Dunn, R Scott; Liu, Chia-Yang; Shie, Feng-Shiun; Lee, Yi-Hsuan; Wills-Karp, Marsha; Chougnet, Claire A; Kallapur, Suhas G; Lewkowich, Ian P; Lindquist, Diana M; Murali-Krishna, Kaja; Kuan, Chia-Yi (2014. ) Blocking lymphocyte trafficking with FTY720 prevents inflammation-sensitized hypoxic-ischemic brain injury in newborns.The Journal of neuroscience : the official journal of the Society for Neuroscience, , 34 (49 ) ,16467-81 More Information

Williams, Michael T; Braun, Amanda A; Amos-Kroohs, Robyn M; McAllister, James P; Lindquist, Diana M; Mangano, Francesco T; Vorhees, Charles V; Yuan, Weihong (2014. ) Kaolin-induced ventriculomegaly at weaning produces long-term learning, memory, and motor deficits in rats.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, , 35 ,7-15 More Information

Sun, Yu-Yo; Morozov, Yury M; Yang, Dianer; Li, Yikun; Dunn, R Scott; Rakic, Pasko; Chan, Pak H; Abe, Koji; Lindquist, Diana M; Kuan, Chia-Yi (2014. ) Synergy of combined tPA-edaravone therapy in experimental thrombotic stroke.PloS one, , 9 (6 ) ,e98807 More Information

Sánchez-Martín, Francisco Javier; Fan, Yunxia; Lindquist, Diana M; Xia, Ying; Puga, Alvaro (2013. ) Lead induces similar gene expression changes in brains of gestationally exposed adult mice and in neurons differentiated from mouse embryonic stem cells.PloS one, , 8 (11 ) ,e80558 More Information

Kim, Hee Kyung; Serai, Suraj; Lindquist, Diana; Merrow, Arnold C; Horn, Paul S; Kim, Dong Hoon; Wong, Brenda L (2015. ) Quantitative Skeletal Muscle MRI: Part 2, MR Spectroscopy and T2 Relaxation Time Mapping-Comparison Between Boys With Duchenne Muscular Dystrophy and Healthy Boys.AJR. American journal of roentgenology, , 205 (2 ) ,W216-23 More Information

Dasgupta, Biplab; Ju, Jeong Sun; Sasaki, Yo; Liu, Xiaona; Jung, Su-Ryun; Higashida, Kazuhiko; Lindquist, Diana; Milbrandt, Jeffrey (2012. ) The AMPK ?2 subunit is required for energy homeostasis during metabolic stress.Molecular and cellular biology, , 32 (14 ) ,2837-48 More Information

Malatesta-Muncher, Rossana; Wansapura, Janaka; Taylor, Michael; Lindquist, Diana; Hor, Kan; Mitsnefes, Mark (2012. ) Early cardiac dysfunction in pediatric patients on maintenance dialysis and post kidney transplant.Pediatric nephrology (Berlin, Germany), , 27 (7 ) ,1157-64 More Information

Herman, James P; Lindquist, Diana; Komoroski, Richard A (2012. ) Linking cerebral metabolic function to stress vulnerability (Commentary on Knapman et al.).The European journal of neuroscience, , 35 (3 ) ,411 More Information

Wu, Jianqiang; Dombi, Eva; Jousma, Edwin; Scott Dunn, R; Lindquist, Diana; Schnell, Beverly M; Kim, Mi-Ok; Kim, Aerang; Widemann, Brigitte C; Cripe, Timothy P; Ratner, Nancy (2012. ) Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging.Pediatric blood & cancer, , 58 (2 ) ,173-80 More Information

Yang, Dianer; Nemkul, Niza; Shereen, Ahmed; Jone, Alice; Dunn, R Scott; Lawrence, Daniel A; Lindquist, Diana; Kuan, Chia-Yi (2009. ) Therapeutic administration of plasminogen activator inhibitor-1 prevents hypoxic-ischemic brain injury in newborns.The Journal of neuroscience : the official journal of the Society for Neuroscience, , 29 (27 ) ,8669-74 More Information

Lindquist, Diana (2008. ) What can 31P MR spectroscopy tell us about muscle disease?.Radiology, , 247 (1 ) ,1-2 More Information

Lindquist, Diana (2007. ) Science to Practice: Is there a role for MR imaging in monitoring gene therapy response?.Radiology, , 243 (3 ) ,611-2 More Information

McNamara, Robert K; Schurdak, Jennifer D; Asch, Ruth H; Peters, Bart D; Lindquist, Diana M (2018. ) Deficits in Docosahexaenoic Acid Accrual during Adolescence Reduce Rat Forebrain White Matter Microstructural Integrity: An in vivo Diffusion Tensor Imaging Study.Developmental neuroscience, , 40 (1 ) ,84-92 More Information

McNamara, Robert K; Asch, Ruth H; Schurdak, Jennifer D; Lindquist, Diana M (2017. ) Glutamate homeostasis in the adult rat prefrontal cortex is altered by cortical docosahexaenoic acid accrual during adolescence: An in vivo1H MRS study.Psychiatry research. Neuroimaging, , 270 ,39-45 More Information

McNamara, Robert K; Schurdak, Jennifer D; Asch, Ruth H; Lindquist, Diana M (2017. ) Omega-3 fatty acid deficiency impairs frontostriatal recruitment following repeated amphetamine treatment in rats: A 7 Tesla in vivo phMRI study.Nutritional neuroscience, , 1-9 More Information

Lindquist, Diana M; Asch, Ruth H; Schurdak, Jennifer D; McNamara, Robert K (2017. ) Effects of dietary-induced alterations in rat brain docosahexaenoic acid accrual on phospholipid metabolism and mitochondrial bioenergetics: An in vivo31P MRS study.Journal of psychiatric research, , 95 ,143-146 More Information

Li, Zhuo; Peng, Yanyan; Hufnagel, Robert B; Hu, Yueh-Chiang; Zhao, Chuntao; Queme, Luis F; Khuchua, Zaza; Driver, Ashley M; Dong, Fei; Lu, Q Richard; Lindquist, Diana M; Jankowski, Michael P; Stottmann, Rolf W; Kao, Winston W Y; Huang, Taosheng (2017. ) Loss of SLC25A46 causes neurodegeneration by affecting mitochondrial dynamics and energy production in mice.Human molecular genetics, , 26 (19 ) ,3776-3791 More Information

He, Quan; Wang, Fangfei; Honda, Takashi; Lindquist, Diana M; Dillman, Jonathan R; Timchenko, Nikolai A; Redington, Andrew N (2017. ) Intravenous miR-144 inhibits tumor growth in diethylnitrosamine-induced hepatocellular carcinoma in mice.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, , 39 (10 ) ,1010428317737729 More Information

McNamara, Robert K; Asch, Ruth H; Lindquist, Diana M; Krikorian, Robert (2017. ) Role of polyunsaturated fatty acids in human brain structure and function across the lifespan: An update on neuroimaging findings.Prostaglandins, leukotrienes, and essential fatty acids, , More Information

Zahedi, Kamyar; Brooks, Marybeth; Barone, Sharon; Rahmati, Negah; Murray Stewart, Tracy; Dunworth, Matthew; Destefano-Shields, Christina; Dasgupta, Nupur; Davidson, Steve; Lindquist, Diana M; Fuller, Christine E; Smith, Roger D; Cleveland, John L; Casero, Robert A; Soleimani, Manoocher (2020. ) Ablation of polyamine catabolic enzymes provokes Purkinje cell damage, neuroinflammation, and severe ataxia.Journal of neuroinflammation, , 17 (1 ) ,301 More Information

Niedbalski, Peter J; Cochran, Alexander S; Akinyi, Teckla G; Thomen, Robert P; Fugate, Elizabeth M; Lindquist, Diana M; Pratt, Ronald G; Cleveland, Zackary I (2020. ) Preclinical hyperpolarized 129 Xe MRI: ventilation and T2 * mapping in mouse lungs at 7 T using multi-echo flyback UTE.NMR in biomedicine, , 33 (7 ) ,e4302 More Information

Emmert, A Scott; Iwasawa, Eri; Shula, Crystal; Schultz, Preston; Lindquist, Diana; Dunn, R Scott; Fugate, Elizabeth M; Hu, Yueh-Chiang; Mangano, Francesco T; Goto, June (2019. ) Impaired neural differentiation and glymphatic CSF flow in the Ccdc39 rat model of neonatal hydrocephalus: genetic interaction with L1cam.Disease models & mechanisms, , 12 (11 ) , More Information

Wang, Mei; Weng, Wen-Chin; Stock, Lauren; Lindquist, Diana; Martinez, Ana; Gourdon, Genevieve; Timchenko, Nikolai; Snape, Mike; Timchenko, Lubov (2019. ) Correction of Glycogen Synthase Kinase 3? in Myotonic Dystrophy 1 Reduces the Mutant RNA and Improves Postnatal Survival of DMSXL Mice.Molecular and cellular biology, , 39 (21 ) , More Information

Emmert, A Scott; Vuong, Shawn M; Shula, Crystal; Lindquist, Diana; Yuan, Weihong; Hu, Yueh-Chiang; Mangano, Francesco T; Goto, June (2019. ) Characterization of a novel rat model of X-linked hydrocephalus by CRISPR-mediated mutation in L1cam.Journal of neurosurgery, , 132 (3 ) ,945-958 More Information

Cincinnati Children's Hospital Medical Center
Phone: 513-636-9268
diana.lindquist@cchmc.org