Robert Lorsbach

Robert Lorsbach , MD,PhD

Professor of Clinical-Affiliate

Cincinnati Childrens Hospital Medical Center
Department of Pathology & Laboratory Medicine
3333 Burnet Ave.
Cincinnati, Ohio 45229
Phone (513) 636-4261


Medical Degree: University of Kansas School of Medicine

Residency: Brigham and Women's Hospital

Doctorate: University of Kansas School of Medicine

Fellowship: Hematopathology: Brigham and Women's Hospital


Peer Reviewed Publications

Cetin, Neslihan; Pandey, Soumya; Lorsbach, Robert B (2015. ) Immature lymphoid cells are a consistent feature of chylothorax in neonates and infants: cytologic features and flow cytometry aid in its distinction from lymphoblastic leukemia/lymphoma.Diagnostic cytopathology, , 43 (4 ) ,335-8 More Information

Cetin, Neslihan; Lorsbach, Robert B (2014. ) Pan myeloid antigen-negative pediatric acute megakaryoblastic leukemia.Pediatric blood & cancer, , 61 (11 ) ,2089-91 More Information

Alapat, Daisy; Coviello-Malle, Jean; Owens, Rebecca; Qu, Pingping; Barlogie, Bart; Shaughnessy, John D; Lorsbach, Robert B (2012. ) Diagnostic usefulness and prognostic impact of CD200 expression in lymphoid malignancies and plasma cell myeloma.American journal of clinical pathology, , 137 (1 ) ,93-100 More Information

Hsi, Eric D; Lorsbach, Robert B; Fend, Falko; Dogan, Ahmet (2011. ) Plasmablastic lymphoma and related disorders.American journal of clinical pathology, , 136 (2 ) ,183-94 More Information

Lorsbach, Robert B; Hsi, Eric D; Dogan, Ahmet; Fend, Falko (2011. ) Plasma cell myeloma and related neoplasms.American journal of clinical pathology, , 136 (2 ) ,168-82 More Information

Lorsbach, Robert B (2010. ) Update on the Diagnosis and Classification of the Plasma Cell Neoplasms.Surgical pathology clinics, , 3 (4 ) ,1061-89 More Information

Lorsbach, Robert B (2004. ) Megakaryoblastic disorders in children. American journal of clinical pathology, , 122 Suppl ,S33-46

Lorsbach, Robert B; Moore, Jennifer; Ang, Sonny O; Sun, Weili; Lenny, Noel; Downing, James R (2004. ) Role of RUNX1 in adult hematopoiesis: analysis of RUNX1-IRES-GFP knock-in mice reveals differential lineage expression.Blood, , 103 (7 ) ,2522-9 More Information

Lorsbach, R B; Moore, J; Mathew, S; Raimondi, S C; Mukatira, S T; Downing, J R (2003. ) TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).Leukemia, , 17 (3 ) ,637-41 More Information

Onciu, Mihaela; Lorsbach, Robert B; Henry, E Charlene; Behm, Frederick G (2002. ) Terminal deoxynucleotidyl transferase-positive lymphoid cells in reactive lymph nodes from children with malignant tumors: incidence, distribution pattern, and immunophenotype in 26 patients.American journal of clinical pathology, , 118 (2 ) ,248-54 More Information

Lorsbach, Robert B; Shay-Seymore, Dominic; Moore, Jennifer; Banks, Peter M; Hasserjian, Robert P; Sandlund, John T; Behm, Frederick G (2002. ) Clinicopathologic analysis of follicular lymphoma occurring in children. Blood, , 99 (6 ) ,1959-64

Lorsbach, R B; McNall, R; Mathew, S (2001. ) Marked bone marrow basophilia in a child with acute myeloid leukemia with a cryptic t(8;21)(q22;q22) chromosomal translocation. Leukemia, , 15 (11 ) ,1799-801

Lorsbach, R B; Downing, J R (2001. ) The role of the AML1 transcription factor in leukemogenesis. International journal of hematology, , 74 (3 ) ,258-65

Greenwald, R J; Boussiotis, V A; Lorsbach, R B; Abbas, A K; Sharpe, A H (2001. ) CTLA-4 regulates induction of anergy in vivo. Immunity, , 14 (2 ) ,145-55

Mathew, S; Lorsbach, R B; Shearer, P; Sandlund, J T; Raimondi, S C (2000. ) Double minute chromosomes and c-MYC amplification in a child with secondary myelodysplastic syndrome after treatment for acute lymphoblastic leukemia. Leukemia, , 14 (7 ) ,1314-5

Lorsbach, R B; Pinkus, G S; Shahsafaei, A; Dorfman, D M (2000. ) Primary marginal zone lymphoma of the thymus.American journal of clinical pathology, , 113 (6 ) ,784-91 More Information

Gao, J J; Filla, M B; Lorsbach, R B; Pace, J L; Crespo, A; Russell, S W; Murphy, W J (2000. ) Prolonged exposure of mouse macrophages to IFN-beta suppresses transcription of the inducible nitric oxide synthase gene: altered availability of transcription factor Stat1alpha. European journal of immunology, , 30 (6 ) ,1551-61

Lorsbach, R B; Folkerth, R D; Pinkus, G S (1999. ) Relapse of acute myelogenous leukemia as a cerebellar myeloblastoma showing megakaryoblastic differentiation. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, , 12 (12 ) ,1186-91

Oosterwegel, M A; Mandelbrot, D A; Boyd, S D; Lorsbach, R B; Jarrett, D Y; Abbas, A K; Sharpe, A H (1999. ) The role of CTLA-4 in regulating Th2 differentiation. Journal of immunology (Baltimore, Md. : 1950), , 163 (5 ) ,2634-9

Oosterwegel, M A; Greenwald, R J; Mandelbrot, D A; Lorsbach, R B; Sharpe, A H (1999. ) CTLA-4 and T cell activation. Current opinion in immunology, , 11 (3 ) ,294-300

Dileepan, K N; Lorsbach, R B; Stechschulte, D J (1993. ) Mast cell granules inhibit macrophage-mediated lysis of mastocytoma cells (P815) and nitric oxide production. Journal of leukocyte biology, , 53 (4 ) ,446-53

Lorsbach, R B; Murphy, W J; Lowenstein, C J; Snyder, S H; Russell, S W (1993. ) Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide. The Journal of biological chemistry, , 268 (3 ) ,1908-13

Pinson, D M; LeClaire, R D; Lorsbach, R B; Parmely, M J; Russell, S W (1992. ) Regulation by transforming growth factor-beta 1 of expression and function of the receptor for IFN-gamma on mouse macrophages. Journal of immunology (Baltimore, Md. : 1950), , 149 (6 ) ,2028-34

Lorsbach, R B; Russell, S W (1992. ) A specific sequence of stimulation is required to induce synthesis of the antimicrobial molecule nitric oxide by mouse macrophages. Infection and immunity, , 60 (5 ) ,2133-5

Niss, Omar; Lorsbach, Robert B; Berger, Mikaela; Chonat, Satheesh; McLemore, Morgan; Buchbinder, David; McCavit, Timothy; Shaffer, Linda G; Simpson, Jessica; Schwartz, Jeffrey H; Meznarich, Jessica; Emberesh, Myesa; Seu, Katie G; Zhang, Wenying; Kalfa, Theodosia A (2021. ) Congenital dyserythropoietic anemia type I: First report from the Congenital Dyserythropoietic Anemia Registry of North America (CDAR).Blood cells, molecules & diseases, , 87 ,102534 More Information

Seu, Katie G; Trump, Lisa R; Emberesh, Sana; Lorsbach, Robert B; Johnson, Clarissa; Meznarich, Jessica; Underhill, Hunter R; Chou, Stella T; Sakthivel, Haripriya; Nassar, Nicolas N; Seu, Kalani J; Blanc, Lionel; Zhang, Wenying; Lutzko, Carolyn M; Kalfa, Theodosia A (2020. ) VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects.American journal of human genetics, , 107 (6 ) ,1149-1156 More Information

Lee, Lynn H; Krupski, Christa; Clark, Jason; Wunderlich, Mark; Lorsbach, Robert B; Grimley, Michael S; Burwinkel, Matthew; Nelson, Adam; Kumar, Ashish R (2020. ) High-risk LCH in infants is serially transplantable in a xenograft model but responds durably to targeted therapy.Blood advances, , 4 (4 ) ,717-727 More Information

Gurunathan, Arun; Boucher, Alexander A; Mark, Melissa; Prus, Kristina M; O'Brien, Maureen M; Breese, Erin H; Mizukawa, Benjamin E; Absalon, Michael J; Nelson, Adam S; Jordan, Michael B; Grimley, Michael S; Lorsbach, Robert B; Rotz, Seth J; Mathanda, Reema; Kumar, Ashish R (2018. ) Limitations of HLH-2004 criteria in distinguishing malignancy-associated hemophagocytic lymphohistiocytosis.Pediatric blood & cancer, , 65 (12 ) ,e27400 More Information

Contact Information

Academic - Cincinnati Childrens Hospital Medical Center
Department of Pathology & Laboratory Medicine
CincinnatiĀ  Ohio, 45229
Phone: (513) 636-4261