Robert Lorsbach, MD, PhD

Medical Degree: University of Kansas School of Medicine

Residency: Brigham and Women's Hospital

Doctorate: University of Kansas School of Medicine

Fellowship: Hematopathology: Brigham and Women's Hospital

Peer Reviewed Publications

Cetin, Neslihan; Pandey, Soumya; Lorsbach, Robert B  (2015). Immature lymphoid cells are a consistent feature of chylothorax in neonates and infants: cytologic features and flow cytometry aid in its distinction from lymphoblastic leukemia/lymphoma. Diagnostic cytopathology, 43 (4) , 335-8More Information

Cetin, Neslihan; Lorsbach, Robert B  (2014). Pan myeloid antigen-negative pediatric acute megakaryoblastic leukemia. Pediatric blood & cancer, 61 (11) , 2089-91More Information

Alapat, Daisy; Coviello-Malle, Jean; Owens, Rebecca; Qu, Pingping; Barlogie, Bart; Shaughnessy, John D; Lorsbach, Robert B  (2012). Diagnostic usefulness and prognostic impact of CD200 expression in lymphoid malignancies and plasma cell myeloma. American journal of clinical pathology, 137 (1) , 93-100More Information

Hsi, Eric D; Lorsbach, Robert B; Fend, Falko; Dogan, Ahmet  (2011). Plasmablastic lymphoma and related disorders. American journal of clinical pathology, 136 (2) , 183-94More Information

Lorsbach, Robert B; Hsi, Eric D; Dogan, Ahmet; Fend, Falko  (2011). Plasma cell myeloma and related neoplasms. American journal of clinical pathology, 136 (2) , 168-82More Information

Lorsbach, Robert B  (2010). Update on the Diagnosis and Classification of the Plasma Cell Neoplasms. Surgical pathology clinics, 3 (4) , 1061-89More Information

Lorsbach, Robert B  (2004). Megakaryoblastic disorders in children. American journal of clinical pathology, 122 Suppl, S33-46

Lorsbach, Robert B; Moore, Jennifer; Ang, Sonny O; Sun, Weili; Lenny, Noel; Downing, James R  (2004). Role of RUNX1 in adult hematopoiesis: analysis of RUNX1-IRES-GFP knock-in mice reveals differential lineage expression. Blood, 103 (7) , 2522-9More Information

Lorsbach, R B; Moore, J; Mathew, S; Raimondi, S C; Mukatira, S T; Downing, J R  (2003). TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). Leukemia, 17 (3) , 637-41More Information

Onciu, Mihaela; Lorsbach, Robert B; Henry, E Charlene; Behm, Frederick G  (2002). Terminal deoxynucleotidyl transferase-positive lymphoid cells in reactive lymph nodes from children with malignant tumors: incidence, distribution pattern, and immunophenotype in 26 patients. American journal of clinical pathology, 118 (2) , 248-54More Information

Lorsbach, Robert B; Shay-Seymore, Dominic; Moore, Jennifer; Banks, Peter M; Hasserjian, Robert P; Sandlund, John T; Behm, Frederick G  (2002). Clinicopathologic analysis of follicular lymphoma occurring in children. Blood, 99 (6) , 1959-64

Lorsbach, R B; McNall, R; Mathew, S  (2001). Marked bone marrow basophilia in a child with acute myeloid leukemia with a cryptic t(8;21)(q22;q22) chromosomal translocation. Leukemia, 15 (11) , 1799-801

Lorsbach, R B; Downing, J R  (2001). The role of the AML1 transcription factor in leukemogenesis. International journal of hematology, 74 (3) , 258-65

Greenwald, R J; Boussiotis, V A; Lorsbach, R B; Abbas, A K; Sharpe, A H  (2001). CTLA-4 regulates induction of anergy in vivo. Immunity, 14 (2) , 145-55

Mathew, S; Lorsbach, R B; Shearer, P; Sandlund, J T; Raimondi, S C  (2000). Double minute chromosomes and c-MYC amplification in a child with secondary myelodysplastic syndrome after treatment for acute lymphoblastic leukemia. Leukemia, 14 (7) , 1314-5

Lorsbach, R B; Pinkus, G S; Shahsafaei, A; Dorfman, D M  (2000). Primary marginal zone lymphoma of the thymus. American journal of clinical pathology, 113 (6) , 784-91More Information

Gao, J J; Filla, M B; Lorsbach, R B; Pace, J L; Crespo, A; Russell, S W; Murphy, W J  (2000). Prolonged exposure of mouse macrophages to IFN-beta suppresses transcription of the inducible nitric oxide synthase gene: altered availability of transcription factor Stat1alpha. European journal of immunology, 30 (6) , 1551-61

Lorsbach, R B; Folkerth, R D; Pinkus, G S  (1999). Relapse of acute myelogenous leukemia as a cerebellar myeloblastoma showing megakaryoblastic differentiation. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 12 (12) , 1186-91

Oosterwegel, M A; Mandelbrot, D A; Boyd, S D; Lorsbach, R B; Jarrett, D Y; Abbas, A K; Sharpe, A H  (1999). The role of CTLA-4 in regulating Th2 differentiation. Journal of immunology (Baltimore, Md. : 1950), 163 (5) , 2634-9

Oosterwegel, M A; Greenwald, R J; Mandelbrot, D A; Lorsbach, R B; Sharpe, A H  (1999). CTLA-4 and T cell activation. Current opinion in immunology, 11 (3) , 294-300

Dileepan, K N; Lorsbach, R B; Stechschulte, D J  (1993). Mast cell granules inhibit macrophage-mediated lysis of mastocytoma cells (P815) and nitric oxide production. Journal of leukocyte biology, 53 (4) , 446-53

Lorsbach, R B; Murphy, W J; Lowenstein, C J; Snyder, S H; Russell, S W  (1993). Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide. The Journal of biological chemistry, 268 (3) , 1908-13

Pinson, D M; LeClaire, R D; Lorsbach, R B; Parmely, M J; Russell, S W  (1992). Regulation by transforming growth factor-beta 1 of expression and function of the receptor for IFN-gamma on mouse macrophages. Journal of immunology (Baltimore, Md. : 1950), 149 (6) , 2028-34

Lorsbach, R B; Russell, S W  (1992). A specific sequence of stimulation is required to induce synthesis of the antimicrobial molecule nitric oxide by mouse macrophages. Infection and immunity, 60 (5) , 2133-5

Niss, Omar; Lorsbach, Robert B; Berger, Mikaela; Chonat, Satheesh; McLemore, Morgan; Buchbinder, David; McCavit, Timothy; Shaffer, Linda G; Simpson, Jessica; Schwartz, Jeffrey H; Meznarich, Jessica; Emberesh, Myesa; Seu, Katie G; Zhang, Wenying; Kalfa, Theodosia A  (2021). Congenital dyserythropoietic anemia type I: First report from the Congenital Dyserythropoietic Anemia Registry of North America (CDAR). Blood cells, molecules & diseases, 87, 102534More Information

Seu, Katie G; Trump, Lisa R; Emberesh, Sana; Lorsbach, Robert B; Johnson, Clarissa; Meznarich, Jessica; Underhill, Hunter R; Chou, Stella T; Sakthivel, Haripriya; Nassar, Nicolas N; Seu, Kalani J; Blanc, Lionel; Zhang, Wenying; Lutzko, Carolyn M; Kalfa, Theodosia A  (2020). VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. American journal of human genetics, 107 (6) , 1149-1156More Information

Lee, Lynn H; Krupski, Christa; Clark, Jason; Wunderlich, Mark; Lorsbach, Robert B; Grimley, Michael S; Burwinkel, Matthew; Nelson, Adam; Kumar, Ashish R  (2020). High-risk LCH in infants is serially transplantable in a xenograft model but responds durably to targeted therapy. Blood advances, 4 (4) , 717-727More Information

Gurunathan, Arun; Boucher, Alexander A; Mark, Melissa; Prus, Kristina M; O'Brien, Maureen M; Breese, Erin H; Mizukawa, Benjamin E; Absalon, Michael J; Nelson, Adam S; Jordan, Michael B; Grimley, Michael S; Lorsbach, Robert B; Rotz, Seth J; Mathanda, Reema; Kumar, Ashish R  (2018). Limitations of HLH-2004 criteria in distinguishing malignancy-associated hemophagocytic lymphohistiocytosis. Pediatric blood & cancer, 65 (12) , e27400More Information

Academic - Cincinnati Childrens Hospital Medical Center
Department of Pathology & Laboratory Medicine
Cincinnati  Ohio, 45229
Phone: (513) 636-4261
Robert.Lorsbach@cchmc.org