Amy Makley

Amy T Makley , MD

Associate Professor of Clinical

Director of Trauma, UC Medical Center; Associate Director, Residency Program in General Surgery

Medical Sciences Building
SRU Room 1577
231 Albert Sabin Way
Cincinnati, Ohio 45267
Phone 513-558-5861
Email amy.makley@uc.edu

Education

Bachelor: University of Dayton Dayton, OH, 2001 (Chemistry)

Medical Degree: University of Cincinnati Cincinnati, OH, 2005

Intern: University of Cincinnati, Cincinnati Cincinnati OH, 2006 (General Surgery)

Research Fellowship: University of Cincinnati Cincinnati, OH, 2010

General Surgery Residency: University of Cincinnati Cincinnati, OH, 2012

Fellowship in Surgical Critical Care: University of Pennsylvania Philadelphia, PA , 2013

Certifications

American Board of Surgery (Surgery Critical Care) (Certification Date: 09-23-2013 )

American Board of Surgery (Certification Date: 03-18-2013 )

Clinical Interests

Critical Care Surgery

General Surgery

Abdominal Hernia

Acalculous Cholecystitis

Adrenal Gland Tumors (Pheochromocytoma)

Adrenal Nodules

Adrenal Rest Tumor

Adrenal Tumors

Adrenocortical Adenoma

Adrenocortical Carcinoma

Aldosteronoma

Appendicitis

Benign adrenal tumors

Bile Duct Stones

Biliary Dyskinesia

Billiary Disease

Bleeding in the Small Bowel

Bowel Obstruction

Cholecystolithiasis

Choledocholithiasis

Cholelithiasis

Colonic Diverticulitis

Diverticular Disease

Diverticulitis

Enterocutaneous Fistula

Femoral Hernia

Fractured Ribs

Gallbladder Inflammation (Cholecystitis)

Gallstones

Groin Hernias

Hernia

Lung Collapse (Pneumothorax)

Peritonitis

Pilonidal Cyst

Pilonidal Dimple

Pilonidal Sinus

Pyloric Stenosis

Traumatic Injury

Umbilical Hernia

Ventral Hernia

Specialities

Surgery

Surgery-Critical Care

Research and Practice Interests

General Surgery, Trauma Surgery, Acute Care Surgery, Hemorrhagic Shock

Positions and Work Experience

- University of Dayton Office for Students with Disabilities, 1997-2001,

- Urban Health Project – Breast and Cervical Cancer Education, 2002,

- Volunteer Instructor of Clinical Surgery, Department of Surgery, University of Cincinnati, Cincinnati, OH, July 2005 – present ,

- Physician, Department of General and Thoracic Surgery, Children’s Hospital Medical Center, Cincinnati, OH, August 2008 – present ,

- House Physician, Medical Staff, Shriners Hospital for Children, Cincinnati, OH, May 2009 – present,

- House Physician, Department of Neurosurgery, Veterans Administration Medical Center, Cincinnati, OH, June 2009 – present,

Research Support

Grant: #1T32GM08478 Investigators:PI: AB Lentsch, PhD; mentor: TA Pritts, MD, PhD 07-2007 -06-2010 NIH Training Grant Role:Fellow

Grant: #Trauma Research Scholarship Investigators:Makley, Amy 07-01-2014 -06-30-2015 EAST Foundation Activation of pulmonary endothelium by microparticles derived from stored red blood cells Role:PI $40,000.00 Awarded Level:Private Non-Profit

Grant: #FA8650-14-2-6B29 / Task under Master FA8650-10-2-6140 Investigators:Goodman, Michael; Makley, Amy 08-22-2014 -12-21-2015 Air Force Research Laboratory Variable saline concentrations for initial resuscitation following polytrauma Role:Collaborator $249,671.00 Awarded Level:Federal

Grant: #FA8650-15-2-6B35 / Task under Master FA8650-10-2-6140 Investigators:Athota, Krishna; Lentsch, Alex; Makley, Amy; Pritts, Timothy 07-15-2015 -01-14-2017 Air Force Research Laboratory Comparison of Combat Gauze with Fibrin Sealant Patch in Hemorrhage Control after Vascular or Hepatic Trauma Role:Collaborator $231,000.00 Awarded Level:Federal

Grant: #FA8650-15-2-6B37 / Task under FA8650-10-2-6140 08-11-2015 -02-10-2017 Air Force Research Laboratory Effects of Early Altitude Exposure following Traumatic Injury and Hemorrhagic Shock Role:PI $215,084.00 Awarded Level:Federal

Grant: #FA8650-16-2-6G04 (Task under Master FA8650-15-2-6605) Investigators:Athota, Krishna; Blakeman, Thomas; Branson, Richard; Goodman, Michael; Makley, Amy 02-01-2016 -01-31-2018 Air Force Research Laboratory Intercostal liposomal bupivacaine for the management of blunt chest trauma Role:Collaborator $271,000.00 Active Level:Federal

Grant: #FA8650-16-2-6G03 (task under Master FA8650-15-2-6605) Investigators:Blakeman, Thomas; Caldwell, Charles; Goodman, Michael; Makley, Amy; Pritts, Timothy 02-22-2016 -02-21-2018 Air Force Research Laboratory A Randomized Controlled Trial for Early Identification and Prevention of Acute Lung Injury After Hemorrhage Role:PI $349,000.00 Awarded Level:Federal

Grant: #FA8650-16-2-6G05 (Task under Master FA8650-15-2-6605) Investigators:Caldwell, Charles; Goodman, Michael; Lentsch, Alex; Makley, Amy; Pritts, Timothy; Robinson, Bryce 02-26-2016 -02-25-2019 Air Force Research Laboratory Effect of fluid resuscitation strategy during en route care on acute lung injury after hemorrhage and burn injury. Role:Collaborator $396,000.00 Awarded Level:Federal

Grant: #FA8650-16-2-6G18 (Task under Master FA8650-15-2-6605) Investigators:Makley, Amy 08-30-2016 -08-29-2017 Air Force Research Laboratory Development and Validation of a Novel Assessment Tool for CCATT Advanced Training Role:PI $61,686.00 Awarded Level:Federal

Grant: #WSU 670097 sub ODHE Investigators:Davis, Bradley; Makley, Amy 02-01-2016 -01-31-2019 Ohio Department of Higher Education Ohio Federal Research Network Role:PI $34,865.00 Active Level:State of Ohio

Grant: #CTA ATB-202 Investigators:Goodman, Michael; Makley, Amy; Pritts, Timothy 01-01-2016 -12-31-2017 Biomedical Advanced Research and Development Authority Phase III, randomized, double-blind, placebo-controlled, parallel-group, study of AB103 as compared to placebo in patients with necrotizing soft tissue infections (NSTI) Role:Collaborator $199,892.16 Active Level:Federal

Grant: #FA8650-17-2-6G26 (Task under FA8650-15-2-6605) Investigators:Makley, Amy; Pritts, Timothy 03-20-2017 -03-19-2020 Air Force Research Laboratory Attenuation of the red blood cell storage lesion to allow extended use of previously cryopreserved pRBC units in austere environments Role:Collaborator $320,000.00 Awarded Level:Federal

Grant: #FA8650-17-2-6G25 (Task under Master FA8650-15-2-6605) Investigators:Goodman, Michael; Makley, Amy 04-13-2017 -04-12-2020 Air Force Research Laboratory Making Tactical Practical – Pragmatic Solutions to Preventing Neurologic Effects of Early Aeromedical Evacuation in the Head Injured Patient Role:Collaborator $323,000.00 Awarded Level:Federal

Grant: #Duke 189925 / 235058 sub UM1AI104681 Investigators:Goodman, Michael; Makley, Amy 01-01-2018 -06-30-2019 National Institute of Allergy and Infectious Diseases An Open-Label Pharmacokinetic Study of Minocycline for Injection Following a Single Infusion in Critically-Ill Adults (ACUMIN) Role:PI $64,605.07 Active Level:Federal

Grant: #FA8650-18-2-6G31 (under Master Agreement FA8650-15-2-6605) Investigators:Goodman, Michael; Makley, Amy; Pritts, Timothy 07-17-2018 -09-28-2021 Air Force Research Laboratory REBOA at Altitude: Efficacy and Effects Role:Collaborator $258,000.00 Awarded Level:Federal

Grant: #K08GM126316 Investigators:Makley, Amy 09-01-2018 -08-31-2022 National Institute of General Medical Sciences Effect of stored blood on sphingosine-1-phosphate mediated vascular barrier integrity Role:PI $199,476.00 Active Level:Federal

Grant: #FA8650-17-2-6G15 (Task under FA8650-15-2-6605) Investigators:Gomaa, Dina; Goodman, Michael; Johannigman, Jay; Makley, Amy 03-20-2017 -01-19-2020 Air Force Research Laboratory Point-of-Care Acute Kidney Injury Biomarker Testing for En Route Combat Casualty Care Role:PI $496,189.00 Active Level:Federal

Publications

Published Abstracts

Makley AT, Friend LAW, Goodman MD, Blanchard JN, Lentsch AB, Pritts TA (04-2009. ) Resuscitation strategy alters response to hemorrhage .[Abstract]Experimental Biology,

Goodman MD. Makley AT, Lentsch AB, Pritts TA (2009. ) Acute alcohol intoxication attenuates the neuroinflammatory response to traumatic brain injury .[Abstract]J Am College Surgeons, 209 (3S ) ,S45

Campion EM, Goodman MD, Makley AT, Huber NL, Clarke CN, Friend LW, Schuster RM, Bailey SR, Lentsch AB, Dorlac WC, Johannigman JA, Pritts TA (2010. ) Hypobaric hypoxia exacerbates the inflammatory response after blunt traumatic brain injury in mice .[Abstract]J Surg Res, 158 ,214

Makley AT, Goodman MD, Friend LA, Bailey SR, Lentsch AB, Pritts TA (2010. ) Damage control resuscitation with aged blood products exacerbates the systemic inflammatory response following hemorrhagic shock .[Abstract]J Surg Res, 158 ,423

Makley AT, Goodman MD, Friend LA, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA (2010. ) Damage control resuscitation with a 1:1 ratio of plasma and packed red blood cells decreases systemic inflammation following hemorrhagic shock in mice .[Abstract]Inflammation Research, 59 (S1 ) ,S28

Peer Reviewed Publications

Makley AT, Goodman MD, Friend LA, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA (2010. ) Murine blood banking: characterization and comparisons to human blood .Shock, , 34 (1 ) ,40 -45

Makley AT, Goodman MD, Friend LA, Deters JS, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA (2010. ) Resuscitation with fresh whole blood ameliorates the inflammatory response after hemorrhagic shock .Journal of Trauma, , 68 (2 ) ,305 -311

Makley AT, Falcone RA (2010. ) Post-traumatic stress disorder in the pediatric patient .Seminars in Pediatric Surgery, , 19 (4 ) ,292 -299

Jernigan, Peter L; Makley, Amy T; Hoehn, Richard S; Edwards, Michael J; Pritts, Timothy A (2015. ) The role of sphingolipids in endothelial barrier function.Biological chemistry, , 396 (6-7 ) ,681-91 More Information

Goodman, Michael D; Makley, Amy T; Campion, Eric M; Friend, Lou Ann W; Lentsch, Alex B; Pritts, Timothy A (2013. ) Preinjury alcohol exposure attenuates the neuroinflammatory response to traumatic brain injury.The Journal of surgical research, , 184 (2 ) ,1053-8 More Information

Belizaire, Ritha M; Makley, Amy T; Campion, Eric M; Sonnier, Dennis I; Goodman, Michael D; Dorlac, Warren C; Friend, Lou Ann; Lentsch, Alex B; Pritts, Timothy A (2012. ) Resuscitation with washed aged packed red blood cell units decreases the proinflammatory response in mice after hemorrhage.The journal of trauma and acute care surgery, , 73 (2 Suppl 1 ) ,S128-33 More Information

Makley, Amy T; Belizaire, Ritha; Campion, Eric M; Goodman, Michael D; Sonnier, Dennis I; Friend, Lou Ann; Schuster, Rebecca M; Bailey, Stephanie R; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A (2012. ) Simulated aeromedical evacuation does not affect systemic inflammation or organ injury in a murine model of hemorrhagic shock. Military medicine, , 177 (8 ) ,911-6

Earnest, Ryan E; Sonnier, Dennis I; Makley, Amy T; Campion, Eric M; Wenke, Joseph C; Bailey, Stephanie R; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A (2012. ) Supplemental oxygen attenuates the increase in wound bacterial growth during simulated aeromedical evacuation in goats.The journal of trauma and acute care surgery, , 73 (1 ) ,80-6 More Information

Makley, Amy T; Goodman, Michael D; Belizaire, Ritha M; Friend, Lou Ann W; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A (2012. ) Damage control resuscitation decreases systemic inflammation after hemorrhage.The Journal of surgical research, , 175 (2 ) ,e75-82 More Information

Sonnier, Dennis I; Makley, Amy T; Friend, Lou Ann W; Bailey, Stephanie R; Lentsch, Alex B; Pritts, Timothy A (2011. ) Hemorrhagic shock induces a proinflammatory milieu in the gut lumen.The Journal of surgical research, , 170 (2 ) ,272-9 More Information

Kasten, Kevin R; Makley, Amy T; Kagan, Richard J (2011. ) Update on the critical care management of severe burns.Journal of intensive care medicine, , 26 (4 ) ,223-36 More Information

Goodman, Michael D; Makley, Amy T; Huber, Nathan L; Clarke, Callisia N; Friend, Lou Ann W; Schuster, Rebecca M; Bailey, Stephanie R; Barnes, Stephen L; Dorlac, Warren C; Johannigman, Jay A; Lentsch, Alex B; Pritts, Timothy A (2011. ) Hypobaric hypoxia exacerbates the neuroinflammatory response to traumatic brain injury.The Journal of surgical research, , 165 (1 ) ,30-7 More Information

Goodman, Michael D; Makley, Amy T; Lentsch, Alex B; Barnes, Stephen L; Dorlac, Gina R; Dorlac, Warren C; Johannigman, Jay A; Pritts, Timothy A (2010. ) Traumatic brain injury and aeromedical evacuation: when is the brain fit to fly?.The Journal of surgical research, , 164 (2 ) ,286-93 More Information

Makley, Amy T; Falcone, Richard A (2010. ) Posttraumatic stress disorder in the pediatric trauma patient.Seminars in pediatric surgery, , 19 (4 ) ,292-9 More Information

Makley, Amy T; Goodman, Michael D; Friend, Lou Ann W; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A (2010. ) Murine blood banking: characterization and comparisons to human blood.Shock (Augusta, Ga.), , 34 (1 ) ,40-5 More Information

Makley, Amy T; Goodman, Michael D; Friend, Lou Ann W; Deters, Joseph S; Johannigman, Jay A; Dorlac, Warren C; Lentsch, Alex B; Pritts, Timothy A (2010. ) Resuscitation with fresh whole blood ameliorates the inflammatory response after hemorrhagic shock.The Journal of trauma, , 68 (2 ) ,305-11 More Information

Goodman, Michael D; Makley, Amy T; Hanseman, Dennis J; Pritts, Timothy A; Robinson, Bryce R H (2015. ) All the bang without the bucks: Defining essential point-of-care testing for traumatic coagulopathy.The journal of trauma and acute care surgery, , 79 (1 ) ,117-24; discussion 1 More Information

Steuerwald, Michael Thomas; Robinson, Bryce R H; Hanseman, Dennis J; Makley, Amy; Pritts, Timothy A (2016. ) Prehospital airway technique does not influence incidence of ventilator-associated pneumonia in trauma patients.The journal of trauma and acute care surgery, , 80 (2 ) ,283-8 More Information

Jung, Andrew; Johnson, Mark; Veile, Rosalie; Friend, Lou Ann; Stevens-Topie, Sabre; Elterman, Joel; Pritts, Timothy; Makley, Amy; Goodman, Michael (2018. ) Variable saline resuscitation in a murine model of combined traumatic brain injury and haemorrhage.Brain injury, , 1-9 More Information

Baker, Jennifer E; Goodman, Michael D; Makley, Amy T; Stevens-Topie, Sabre M; Veile, Rosalie A; Mahoney, Eric J; Heyl, Judy R; Cox, Daniel B; Pritts, Timothy A; Athota, Krishna P (2018. ) Evaluation of a Novel Fibrin Sealant Patch in Hemorrhage Control After Vascular or Hepatic Injury.Military medicine, , More Information

Martin, Grace E; He, Heng; Makley, Amy T; Pritts, Timothy A; Elterman, Joel B; Johannigman, Jay A; Goodman, Michael D (2018. ) Proximal penetrating extremity injuries-An opportunity to decrease overtriage?.The journal of trauma and acute care surgery, , 85 (1 ) ,122-127 More Information

Martin, Grace; Shah, Dhavan; Elson, Nora; Boudreau, Ryan; Hanseman, Dennis; Pritts, Timothy A; Makley, Amy T; Foreman, Brandon; Goodman, Michael D (2018. ) Relationship of Coagulopathy and Platelet Dysfunction to Transfusion Needs After Traumatic Brain Injury.Neurocritical care, , 28 (3 ) ,330-337 More Information

Martin, Grace E; Carroll, Christopher P; Plummer, Zachary J; Millar, D A; Pritts, Timothy A; Makley, Amy T; Joseph, Bellal A; Ngwenya, Laura B; Goodman, Michael D (2018. ) Safety and efficacy of brain injury guidelines at a Level III trauma center.The journal of trauma and acute care surgery, , 84 (3 ) ,483-489 More Information

Miano, Todd A; Cuker, Adam; Christie, Jason D; Martin, Niels; Smith, Brian; Makley, Amy T; Guo, Wensheng; Hennessy, Sean (2018. ) Comparative Effectiveness of Enoxaparin vs Dalteparin for Thromboprophylaxis After Traumatic Injury.Chest, , 153 (1 ) ,133-142 More Information

Martin, Grace E; Xia, Brent; Kim, Young; Johnson, Mark D; Veile, Rosalie; Friend, Lou Ann; Makley, Amy T; Caldwell, Charles C; Goodman, Michael D (2017. ) Platelet Function Changes in a Time-Dependent Manner Following Traumatic Brain Injury in a Murine Model.Shock (Augusta, Ga.), , More Information

Boudreau, Ryan M; Johnson, Mark; Veile, Rosalie; Friend, Lou Ann; Goetzman, Holly; Pritts, Timothy A; Caldwell, Charles C; Makley, Amy T; Goodman, Michael D (2017. ) Impact of tranexamic acid on coagulation and inflammation in murine models of traumatic brain injury and hemorrhage.The Journal of surgical research, , 215 ,47-54 More Information

Kassam, Al-Faraaz; Cortez, Alexander R; Diwan, Tayyab S; Bailey, Amanda; Mirza, Ahmad; Sussman, Jeffrey J; Makley, Amy T; Quillin, Ralph Cutler (2019. ) Return to the Real World: A Novel Program to Improve Resident Readiness for the Transplant Surgery Rotation.Journal of surgical education, , More Information

Winer, Leah K; Cortez, Alex R; Kassam, Al; Quillin, Ralph C; Goodman, Michael D; Makley, Amy T; Sussman, Jeffrey J; Kuethe, Joshua W (2019. ) The Impact of a Comprehensive Resident Curriculum and Required Participation in "This Week in SCORE" on General Surgery ABSITE Performance and Well-Being.Journal of surgical education, , More Information

Morris, Mackenzie C; Bercz, Aron; Niziolek, Grace M; Kassam, Farzaan; Veile, Rose; Friend, Lou Ann; Pritts, Timothy A; Makley, Amy T; Goodman, Michael D (2019. ) UCH-L1 is a Poor Serum Biomarker of Murine Traumatic Brain Injury After Polytrauma.The Journal of surgical research, , 244 ,63-68 More Information

Morris, Mackenzie C; Kassam, Farzaan; Bercz, Aron; Beckmann, Nadine; Schumacher, Fabian; Gulbins, Erich; Makley, Amy T; Goodman, Michael D (2019. ) The Role of Chemoprophylactic Agents in Modulating Platelet Aggregability After Traumatic Brain Injury.The Journal of surgical research, , 244 ,1-8 More Information

Baker, Jennifer E; Niziolek, Grace M; Elson, Nora C; Pugh, Amanda M; Nomellini, Vanessa; Makley, Amy T; Pritts, Timothy A; Goodman, Michael D (2019. ) Optimizing Lower Extremity Duplex Ultrasound Screening After Traumatic Injury.The Journal of surgical research, , 243 ,143-150 More Information

Martin, Grace E; Pugh, Amanda M; Moran, Ryan; Veile, Rose; Friend, Lou Ann; Pritts, Timothy A; Makley, Amy T; Caldwell, Charles C; Goodman, Michael D (2019. ) Microvesicles generated following traumatic brain injury induce platelet dysfunction via adenosine diphosphate receptor.The journal of trauma and acute care surgery, , 86 (4 ) ,592-600 More Information

Martin, Grace E; Johnson, Mark; Veile, Rose; Friend, Lou Ann; Elterman, Joel B; Johannigman, Jay A; Pritts, Timothy A; Goodman, Michael D; Makley, Amy T (2019. ) Effects of Early Altitude Exposure on the Open Abdomen After Laparotomy in Trauma.Military medicine, , More Information

Martin, Grace E; Pugh, Amanda; Williams, Susan G; Hanseman, Dennis; Nomellini, Vanessa; Makley, Amy T; Pritts, Timothy A; Goodman, Michael D (2019. ) Lower Extremity Duplex Ultrasound Screening Protocol for Moderate- and High-Risk Trauma Patients.The Journal of surgical research, , 235 ,280-287 More Information

Boudreau, Ryan M; Deshpande, Keshav K; Day, Gregory M; Hinckley, William R; Harger, Nicole; Pritts, Timothy A; Makley, Amy T; Goodman, Michael D (2019. ) Prehospital Tranexamic Acid Administration During Aeromedical Transport After Injury.The Journal of surgical research, , 233 ,132-138 More Information

Baker, Jennifer E; Martin, Grace E; Katsaros, Gianna; Lewis, Hannah V; Wakefield, Connor J; Josephs, Sean A; Nomellini, Vanessa; Makley, Amy T; Goodman, Michael D (2018. ) Variability of fluid administration during exploratory laparotomy for abdominal trauma.Trauma surgery & acute care open, , 3 (1 ) ,e000240 More Information

Dhar V.K.;Hanseman D.J.;Young G.;Browne D.;Makley A.T.;Sussman J.J.;Goodman M.D. (03-01-2020. ) Does Geographical Bias Impact the Match for General Surgery Residents?.Journal of Surgical Education, , 77 (2 ) ,260-266 More Information

Morris M.C.;Kim Y.;Blakeman T.C.;Stevens-Topie S.;Jung A.D.;Cox D.B.;Robinson B.B.R.;Pritts T.A.;Makley A.T.;Goodman M.D. (03-01-2020. ) Early Identification of Acute Lung Injury in a Porcine Model of Hemorrhagic Shock.Journal of Surgical Research, , 247 ,453-460 More Information

Morris M.;Singer K.;Niziolek G.;McGlone E.;Veile R.;Friend L.;Makley A.;Goodman M. (02-01-2020. ) Oxygenation extremes after traumatic brain injury transiently affect coagulation.Thrombosis Research, , 186 ,58-63 More Information

Baker J.E.;Martin G.E.;Katsaros G.;Lewis H.V.;Wakefield C.J.;Josephs S.A.;Nomellini V.;Makley A.T.;Goodman M.D. (01-01-2018. ) Variability of fluid administration during exploratory laparotomy for abdominal trauma.Trauma Surgery and Acute Care Open, , 3 (1 ) , More Information

Kasten K.;Makley A.;Kagan R. (12-01-2011. ) Burn and Inhalation Injuries.Pediatric Critical Care, , 1489-1499 More Information

Cohen M.;Makley A.;Cushieri J.;Schreiber M.;Spinella P. (02-01-2010. ) Discussion.Journal of Trauma - Injury, Infection and Critical Care, , 68 (2 ) ,310-311 More Information

Singer, Kathleen E; Morris, Mackenzie C; Blakeman, Christopher; Stevens-Topie, Sabre M; Veile, Rosalie; Fortuna, Gerald; DuBose, Joseph J; Stuever, Mary F; Makley, Amy T; Goodman, Michael D (2020. ) Can Resuscitative Endovascular Balloon Occlusion of the Aorta Fly? Assessing Aortic Balloon Performance for Aeromedical Evacuation.The Journal of surgical research, , 254 ,390-397 More Information

Kassam, Al-Faraaz; Singer, Kathleen E; Winer, Leah K; Browne, Deborah; Sussman, Jeffrey J; Goodman, Michael D; Makley, Amy T (2020. ) Acquisition and retention of surgical skills taught during intern surgical boot camp.American journal of surgery, , More Information

Niziolek, Grace M; Boudreau, Ryan M; Baker, Jennifer; Friend, Lou Ann; Makley, Amy T; Edwards, Michael J; Gulbins, Erich; Goodman, Michael D (2020. ) Acid Sphingomyelinase Inhibition Mitigates Histopathological and Behavioral Changes in a Murine Model of Traumatic Brain Injury.Journal of neurotrauma, , 37 (17 ) ,1902-1909 More Information

Morris, Mackenzie C; John, Devin; Singer, Kathleen E; Moran, Ryan; McGlone, Emily; Veile, Rosalie; Goetzman, Holly S; Makley, Amy T; Caldwell, Charles C; Goodman, Michael D (2020. ) Post-TBI splenectomy may exacerbate coagulopathy and platelet activation in a murine model.Thrombosis research, , 193 ,211-217 More Information

Pulliam, Kasiemobi E; Joseph, Bernadin; Makley, Amy T; Caldwell, Charles C; Lentsch, Alex B; Goodman, Michael D; Pritts, Timothy A (2020. ) Washing packed red blood cells decreases red blood cell storage lesion formation.Surgery, , More Information

Pulliam, Kasiemobi E; Joseph, Bernadin; Veile, Rosalie A; Friend, Lou Ann; Makley, Amy T; Caldwell, Charles C; Lentsch, Alex B; Goodman, Michael D; Pritts, Timothy A (2020. ) Expired But Not Yet Dead: Examining the Red Blood Cell Storage Lesion in Extended-Storage Whole Blood.Shock (Augusta, Ga.), , More Information

Wagner, Monica L; Streit, Stephanie; Makley, Amy T; Pritts, Timothy A; Goodman, Michael D (2020. ) Hepatic Pseudoaneurysm Incidence After Liver Trauma.The Journal of surgical research, , 256 ,623-628 More Information

Morris, Mackenzie C; Niziolek, Grace M; Baker, Jennifer E; Huebner, Benjamin R; Hanseman, Dennis; Makley, Amy T; Pritts, Timothy A; Goodman, Michael D (2020. ) Death by Decade: Establishing a Transfusion Ceiling for Futility in Massive Transfusion.The Journal of surgical research, , 252 ,139-146 More Information

Kassam, Al-Faraaz; Cortez, Alexander R; Winer, Leah K; Baker, Jennifer E; Hanseman, Dennis J; Wells, Dennis; Yalamanchili, Suma; Habashy, Engy; Chausse, Steve; Makley, Amy T; Goodman, Michael D; Sussman, Jeffrey J; Quillin, Ralph C (2020. ) Swipe right for surgical residency: Exploring the unconscious bias in resident selection.Surgery, , More Information

Pulliam, Kasiemobi E; Joseph, Bernadin; Morris, Mackenzie C; Veile, Rosalie A; Schuster, Rebecca M; Makley, Amy T; Pritts, Timothy A; Goodman, Michael D (2020. ) Innate coagulability changes with age in stored packed red blood cells.Thrombosis research, , 195 ,35-42 More Information

Wagner, Monica L; Farooqui, Zishaan; Elson, Nora C; Makley, Amy T; Pritts, Timothy A; Goodman, Michael D (2020. ) Characterizing Early Inpatient Death After Trauma.The Journal of surgical research, , 255 ,405-410 More Information

Pulliam, Kasiemobi E; Joseph, Bernadin; Veile, Rosalie A; Friend, Lou Ann; Makley, Amy T; Caldwell, Charles C; Lentsch, Alex B; Goodman, Michael D; Pritts, Timothy A (2020. ) SAVE IT - DON'T WASTE IT! MAXIMIZING UTILIZATION OF ERYTHROCYTES FROM PREVIOUSLY STORED WHOLE BLOOD.The journal of trauma and acute care surgery, , More Information

Farrar, Julie Elizabeth; Droege, Molly Elizabeth; Philpott, Carolyn Dosen; Mueller, Eric William; Ernst, Neil Edward; Makley, Amy Teres; Deichstetter, Kaley Marie; Droege, Christopher Allen (2021. ) Impact of Weight on Anti-Xa Attainment in High-Risk Trauma Patients on Enoxaparin Chemoprophylaxis.The Journal of surgical research, , 264 ,425-434 More Information

Singer, Kathleen E; Philpott, Carolyn D; Bercz, Aron P; Phillips, Tabatha; Salyer, Christen E; Hanseman, Dennis; Droege, Molly E; Goodman, Michael D; Makley, Amy T (2021. ) Impact of a Multimodal Analgesia Protocol on Inpatient and Outpatient Opioid Use in Acute Trauma.The Journal of surgical research, , 268 ,9-16 More Information

Singer, Kathleen E; Bercz, Aron P; Morris, Mackenzie C; Elson, Nora C; Wallen, Taylor E; Hanseman, Dennis; Pritts, Timothy A; Nomellini, Vanessa; Patel, Sameer H; Makley, Amy T; Goodman, Michael D (2021. ) Acute and chronic hematologic implications of emergency and elective splenectomy.The Journal of surgical research, , 267 ,197-202 More Information

Rashidi, Hooman H; Makley, Amy; Palmieri, Tina L; Albahra, Samer; Loegering, Julia; Fang, Lei; Yamaguchi, Kensuke; Gerlach, Travis; Rodriquez, Dario; Tran, Nam K (2021. ) Enhancing Military Burn- and Trauma-Related Acute Kidney Injury Prediction Through an Automated Machine Learning Platform and Point-of-Care Testing.Archives of pathology & laboratory medicine, , 145 (3 ) ,320-326 More Information

Niziolek, Grace M; Hoehn, Richard S; Seitz, Aaron P; Jernigan, Peter L; Makley, Amy T; Gulbins, Erich; Edwards, Michael J; Goodman, Michael D (2021. ) The Role of Acid Sphingomyelinase Inhibition in Repetitive Mild Traumatic Brain Injury.The Journal of surgical research, , 259 ,296-304 More Information

Lodise, Thomas P; Van Wart, Scott; Sund, Zoe M; Bressler, Adam M; Khan, Akram; Makley, Amy T; Hamad, Yasir; Salata, Robert A; Silveira, Fernanda P; Sims, Matthew D; Kabchi, Badih A; Saad, Mohamed A; Brown, Carrie; Oler, Randolph E; Fowler, Vance; Wunderink, Richard G (2021. ) Pharmacokinetic and Pharmacodynamic Profiling of Minocycline for Injection following a Single Infusion in Critically Ill Adults in a Phase IV Open-Label Multicenter Study (ACUMIN).Antimicrobial agents and chemotherapy, , 65 (3 ) , More Information

Book Chapter

Makley AT. (2008 ) Spleen The Mont Reid Surgical Handbook, 6th edition .Philadelphia, PA, Mosby

Makley AT. (2008 ) Surgical Skin Diseases The Mont Reid Surgical Handbook, 6th edition .Philadelphia, PA, Mosby

Kasten KR, Makley AT, Kagan RJ (2010 ) Burn and Inhalational Injuries Pediatric Critical Care, 4th edition .New York, NY, Elsevier

Makley AT, Sonnier DS, Pritts TA (2010 ) Small Intestine Surgery Review Illustrated, 2nd edition .New York, NY, McGraw-Hill Professional

Presentations

Poster Presentations

Makley AT, Friend LAW, Goodman MD, Blanchard JN, Lentsch AB, Pritts TA. (04-2009. ) Resuscitation strategy alters response to hemorrhage .Scientific exhibit. Experimental Biology 2009, New Orleans, Louisiana,

Makley AT, Friend LAW, Goodman MD, Blanchard JN, Lentsch AB, Pritts TA. (05-2009. ) Resuscitation strategy alters inflammatory response to hemorrhage .Scientific exhibit. Ohio Chapter, American College of Surgeons, Cleveland, Ohio,

Makley AT. Goodman MD, Friend LAW, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA. (08-2009. ) Damage control resuscitation with aged blood worsens the inflammatory response following hemorrhage in mice .Scientific exhibit, Advanced Technology Applications for Combat Casualty Care, St. Petersburg, Florida,

Goodman MD, Campion EM, Makley AT, Huber NL, Clarke CN, Friend LAW, Schuster RM, Bailey SR, Lentsch AB, Dorlac WC, Johannigman JA, Pritts TA. (08-2009. ) The inflammatory response after blunt traumatic brain injury is aggravated by hypobaric hypoxic in mice .Scientific exhibit, Advanced Technology Applications for Combat Casualty Care, St. Petersburg, Florida,

Paper Presentations

Makley AT, Pritts TA. (03-2009. ) Update to USAF Air Mobility Command on effects of altitude after injury .Cincinnati, Ohio.

Makley AT. (03-2009. ) Hemorrhagic shock and resuscitation strategy .

Makley AT, Goodman MD, Friend LAW, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA. (05-2009. ) Transfusion of stored blood components increases systemic inflammation following hemorrhage .

Makley AT, Goodman MD, Friend LAW, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA. (05-2009. ) Transfusion of stored blood components increases the inflammatory response to hemorrhagic shock .

Makley AT. (06-2009. ) Effects of different resuscitation strategies on inflammation and organ dysfunction following hemorrhagic shock .

Makley AT. (07-2009. ) Damage control resuscitation with aged blood worsens the inflammatory response following hemorrhage in mice .

Huber NL, Sonnier DI, Goodman MD, Makley AT, Bailey SR, Schuster RM, Clarke CN, Friend LAW, Lentsch AB, Dorlac WC, Johannigman JA, Pritts TA. (08-2009. ) Hypobaric exposure immediately after burn injury intensifies systemic and intestinal inflammation .

Makley AT. Goodman MD, Friend LAW, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA. (08-2009. ) Damage control resuscitation with aged blood worsens the inflammatory response following hemorrhage in mice .

Goodman MD, Makley AT, Lentsch AB, Barnes SL, Dorlac GR, Dorlac WC, Johannigman JA, Pritts TA. (08-2009. ) Traumatic brain injury and aeromedical evacuation: when is the brain fit to fly? .

Huber NL, Makley AT, Goodman MD, Bailey SR, Schuster RM, Clarke CN, Friend LAW, Lentsch AB, Dorlac WC, Johannigman JA, Pritts TA. (08-2009. ) Hypobaric exposure after burn injury: effects of systemic and intestinal inflammation .

Makley AT, Goodman MD, Friend LAW, Schuster RM, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA. (10-2009. ) Fresh whole blood resuscitation attenuates the inflammatory cytokine response to hemorrhage .

Goodman MD, Makley AT, Lentsch AB, Pritts. (10-2009. ) Acute alcohol intoxication attenuates the neuroinflammatory response to traumatic brain injury .

Makley AT (11-2009. ) Resuscitation with fresh blood products attenuates the inflammatory response to hemorrhagic shock .Dublin, OH.

Makley AT (11-2009. ) Resuscitation with fresh blood products attenuates the inflammatory response to hemorrhagic shock .Indianapolis, IN.

Campion EM, Goodman MD, Makley AT, Huber NL, Clarke CN, Friend LW, Schuster RM, Bailey SR, Lentsch AB, Dorlac WC, Johannigman JA, Pritts TA (02-2010. ) Hypobaric hypoxia exacerbates the inflammatory response after blunt traumatic brain injury in mice .San Antonio, TX.

Makley AT, Goodman MD, Friend LA, Bailey SR, Lentsch AB, Pritts TA (02-2010. ) Damage control resuscitation with aged blood products exacerbates the systemic inflammatory response following hemorrhagic shock .San Antonio, TX.

Makley AT (02-2010. ) The inflammatory response to hemorrhagic shock and resuscitation .Fort Sam Houston, TX.

Makley AT, Goodman MD, Friend LA, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA (03-2010. ) Damage control resuscitation with a 1:1 ratio of plasma and packed red blood cells decreases systemic inflammation following hemorrhagic shock in mice .Munich, Germany.

Earnest RE, Sonnier DI, Makley AT, Campion EM, Bailey SR, Lentsch AB, Pritts TA, Johannigman JA, Dorlac WC (04-2010. ) Effect of altitude on wound infection using a complex musculoskeletal wound model in domestic goats .San Antonio, TX.

Makley AT, Goodman MD, Friend LA, Dorlac WC, Johannigman JA, Lentsch AB, Pritts TA (05-2010. ) Damage control resuscitation with a 1:1 ratio of plasma to packed red blood cells attenuates systemic inflammation following hemorrhage in mice .Columbus, OH.

Makley AT, Goodman MD, Friend LA, Johannigman JA, Dorlac, WC, Lentsch AB, Pritts TA (06-2010. ) A high ratio of plasma:pRBCs attenuates systemic inflammation following hemorrhagic shock in mice .Cincinnati, OH.

Makley AT, Campion, EM, Sonnier DI, Friend LA, Schuster RM, Bailey SR, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA (2010. ) Hypobaric hypoxia does not increase early inflammatory response to resuscitation following hemorrhagic shock in mice .

Makley AT, Goodman MD, Friend LA, Johannigman JA, Dorlac, WC, Lentsch AB, Pritts TA (2010. ) Damage control resuscitation with a 1:1 ratio of plasma and packed red blood cells attenuates inflammation and capillary leak following hemorrhage in mice .

Earnest RE, Sonnier DI, Makley AT, Campion EM, Wenke JC, Bailey BS, Lentsch AB, Pritts TA, Johannigman JA, Dorlac WN (2010. ) Supplemental oxygen decreases wound bacterial growth after simulated aeromedical evacuation in goats .

Makley AT, Goodman MD, Friend LAW, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA (2010. ) Damage control resuscitation with a 1:1 ratio of plasma and packed red blood cells attenuates inflammation and capillary leak following hemorrhage in mice .

Makley AT, Campion EC, Sonnier DI, Friend LAW, Schuster RM, Bailey SR, Johannigman JA, Dorlac WC, Lentsch AB, Pritts TA (2010. ) Hypobaric hypoxia does not increase early inflammatory response to resuscitation following hemorrhagic shock in mice .

Honors and Awards

Salutatorian, Troy High School, Troy, Ohio, 1997

National Merit Scholar, 1997

Robert C. Byrd Scholarship, 1997-2001

Dean’s List, University of Dayton, all semesters, 1997-2001

University of Dayton President’s Award, 1997-2001

Geriatric Medicine Award, Ohio Department of Aging, 2005

University of Cincinnati Best Teaching Resident, 2007

University of Cincinnati Resident Research Competition finalist, 2009

Cincinnati Surgical Society Resident Research Competition winner, 2009

Nominee, American College of Surgeons Resident Award for Exemplary Teaching, 2009

Winner, American College of Surgeons, Ohio Committee on Trauma, Resident Trauma Paper Competition, 2009

Finalist, Arthur E. Baue Young Investigator Award, Trauma, Shock, Inflammation, and Sepsis 8th World Congress, 2010

First place, Annual Resident Research Forum, Basic Science Category, Ohio Chapter of the American College of Surgeons, 2010

Finalist, University of Cincinnati Resident Research Competition, 2010

Alpha Omega Alpha, University of Cincinnati, 2010

2017 Great Leaders Under 40 Award Class of 2017

2019 UC Emergency Medicine and Trauma teams under the direction of Dr. Amy Makley were named the recipient of the “Heroes in Action Award” as a special part of the Cincinnati Business Courier' Health Care Heroes

Professional Affiliation

07-2008 -06-2010: Post-Doctoral Research Fellow, Department of Surgery, University of Cincinnati; Advisors: Dr. Timothy Pritts and Dr. Alex Lentsch. Research focus: Hemorrhagic shock and damage control resuscitation.

05-2000 -05-2001: Senior Thesis Project, University of Dayton, Department of Biochemistry: Effects of Clofibrate and Vitamin E on Liver and Intestinal Fatty Acid Binding Proteins. Advisor: Dr. Sanford Singer.

05-1998 -08-1998: Research Assistant, Wright Patterson Air Force Base – Nonmetallic Polymer Branch. Advisor: Dr. Albert Fratini.

2008 -To Present: Candidate Member, Society of American Gastrointestinal and Endoscopic Surgeons

2009 -To Present: Resident Member, American College of Surgeons

2005 -To Present: Resident Member, Association of Women Surgeons

2005 -To Present: Resident Member, Cincinnati Surgical Society

2001 -2005: Student Member, American Medical Women’s Association (Co-chairperson 2004-2005)

2001 -2005: Student Member, American Medical Association

2001 -2005: Member, American Chemical Society

Contact Information

Academic - Medical Sciences Building
SRU Room 1577
Cincinnati  Ohio, 45267
Phone: 513-558-5861
amy.makley@uc.edu