Anthony E Mascia, PhD

Bachelor of Science: Fordham University New York City, NY, 1998 (Physics)

Master of Science: University of California, Los Angeles (UCLA) Los Angeles, CA, (Biomedical Physics)

Doctor of Philosophy: University of California, Los Angeles (UCLA) Los Angeles, CA, (Biomedical Physics)

Peer Reviewed Publications

Delaney, Alexander R; Dong, Lei; Mascia, Anthony; Zou, Wei; Zhang, Yongbin; Yin, Lingshu; Rosas, Sara; Hrbacek, Jan; Lomax, Antony J; Slotman, Ben J; Dahele, Max; Verbakel, Wilko F A R  (2018). Automated Knowledge-Based Intensity-Modulated Proton Planning: An International Multicenter Benchmarking Study. Cancers, 10 (11) More Information

Pater, Luke; Turpin, Brian; Mascia, Anthony  (2017). Pencil Beam Scanning Proton Therapy for Rhabdomyosarcoma of the Biliary Tract. Cureus, 9 (10) , e1747More Information

Mascia, Anthony E; Daugherty, Emily C; Zhang, Yongbin; Lee, Eunsin; Xiao, Zhiyan; Sertorio, Mathieu; Woo, Jennifer; Backus, Lori R; McDonald, Julie M; McCann, Claire; Russell, Kenneth; Levine, Lisa; Sharma, Ricky A; Khuntia, Dee; Bradley, Jeffrey D; Simone, Charles B; Perentesis, John P; Breneman, John C  (2022). Proton FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases: The FAST-01 Nonrandomized Trial. JAMA oncologyMore Information

Daugherty, Emily C; Mascia, Anthony E; Zhang, Yongbin; Lee, Eunsin; Xiao, Zhiyan; Sertorio, Mathieu; Woo, Jennifer; McCann, Claire; Russell, Kenneth J; Levine, Lisa L; Sharma, Ricky A; Khuntia, Deepak; Bradley, Jeffrey; Simone Nd, Charles B; Perentesis, John P; Breneman, John C  (2022). FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases (FAST-01): Protocol for the First Prospective Feasibility Study. JMIR research protocolsMore Information

Xiao, Zhiyan; Zhang, Yongbin; Speth, Joseph; Lee, Eunsin; Mascia, Anthony; Lamba, Michael  (2022). Evaluation of a conventionally shielded proton treatment room for FLASH radiotherapy. Medical physicsMore Information

Williams, Michael T; Sugimoto, Chiho; Regan, Samantha L; Pitzer, Emily M; Fritz, Adam L; Sertorio, Mathieu; Mascia, Anthony E; Vatner, Ralph E; Perentesis, John P; Vorhees, Charles V  (2022). Cognitive and behavioral effects of whole brain conventional or high dose rate (FLASH) proton irradiation in a neonatal Sprague Dawley rat model. PloS one, 17 (9) , e0274007More Information

Lee, Eunsin; Lourenço, Ana Mónica; Speth, Joseph; Lee, Nigel; Subiel, Anna; Romano, Francesco; Thomas, Russell; Amos, Richard A; Zhang, Yongbin; Xiao, Zhiyan; Mascia, Anthony  (2022). Ultrahigh dose rate pencil beam scanning proton dosimetry using ion chambers and a calorimeter in support of first in-human FLASH clinical trial. Medical physics, 49 (9) , 6171-6182More Information

Nelson, Bailey; Tadesse, Dawit G; Sudhoff, Mickaela; Wang, Kyle; Meier, Teresa; Mascia, Anthony; Kharofa, Jordan  (2022). Hematologic Toxicity Comparison of Intensity Modulated Proton Therapy and Intensity Modulated Radiation Therapy in Anal Cancer Patients. American journal of clinical oncology, 45 (6) , 264-267More Information

Breneman, John; Perentesis, John P; Bradley, Jeffrey; Mascia, Anthony; Abel, Eric; Sharda, Agam; Khuntia, Deepak; Sharma, Ricky A; Simone, Charles B  (2021). In Regard to Buchsbaum et al. International journal of radiation oncology, biology, physics, 110 (5) , 1544-1545More Information

Hua, Chia-Ho; Mascia, Anthony E; Seravalli, Enrica; Lomax, Antony J; Seiersen, Klaus; Ulin, Kenneth  (2021). Advances in radiotherapy technology for pediatric cancer patients and roles of medical physicists: COG and SIOP Europe perspectives. Pediatric blood & cancer, 68 Suppl 2, e28344More Information

Cunningham, Shannon; McCauley, Shelby; Vairamani, Kanimozhi; Speth, Joseph; Girdhani, Swati; Abel, Eric; Sharma, Ricky A; Perentesis, John P; Wells, Susanne I; Mascia, Anthony; Sertorio, Mathieu  (2021). FLASH Proton Pencil Beam Scanning Irradiation Minimizes Radiation-Induced Leg Contracture and Skin Toxicity in Mice. Cancers, 13 (5) More Information

Sertorio, Mathieu; Nowrouzi, Ali; Akbarpour, Mahdi; Chetal, Kashish; Salomonis, Nathan; Brons, Stephan; Mascia, Anthony; Ionascu, Dan; McCauley, Shelby; Kupneski, Taylor; Köthe, Andreas; Debus, Jürgen; Perentesis, John P; Abdollahi, Amir; Zheng, Yi; Wells, Susanne I  (2021). Differential transcriptome response to proton versus X-ray radiation reveals novel candidate targets for combinatorial PT therapy in lymphoma. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 155, 293-303More Information

Williams, Michael T; Sugimoto, Chiho; Regan, Samantha L; Pitzer, Emily M; Fritz, Adam L; Mascia, Anthony E; Sertorio, Mathieu; Vatner, Ralph E; Perentesis, John P; Vorhees, Charles V  (2020). Whole brain proton irradiation in adult Sprague Dawley rats produces dose dependent and non-dependent cognitive, behavioral, and dopaminergic effects. Scientific reports, 10 (1) , 21584More Information

Lee, Eunsin; Perry, Daniel; Speth, Joseph; Zhang, Yongbin; Xiao, Zhiyan; Mascia, Anthony  (2020). Measurement-based study on characterizing symmetric and asymmetric respiratory motion interplay effect on target dose distribution in the proton pencil beam scanning. Journal of applied clinical medical physics, 21 (4) , 59-67More Information

Sertorio, Mathieu; Perentesis, John P; Vatner, Ralph E; Mascia, Anthony E; Zheng, Yi; Wells, Susanne I  (2018). Cancer Cell Metabolism: Implications for X-ray and Particle Radiation Therapy. International journal of particle therapy, 5 (1) , 40-48More Information

Meier, Teresa; Mascia, Anthony; Wolf, Eric; Kharofa, Jordan  (2017). Dosimetric Comparison of Intensity-Modulated Proton Therapy and Volumetric-Modulated Arc Therapy in Anal Cancer Patients and the Ability to Spare Bone Marrow. International journal of particle therapy, 4 (2) , 11-17More Information

Shukla, Samriddhi; Saha, Taniya; Rama, Nihar; Acharya, Anusha; Le, Tien; Bian, Fenghua; Donovan, Johnny; Tan, Lin Abigail; Vatner, Ralph; Kalinichenko, Vladimir; Mascia, Anthony; Perentesis, John P; Kalin, Tanya V  (2023). Ultra-high dose-rate proton FLASH improves tumor control. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 186, 109741More Information

Mascia, Anthony; McCauley, Shelby; Speth, Joseph; Nunez, Stefanno Alarcon; Boivin, Gael; Vilalta, Marta; Sharma, Ricky A; Perentesis, John P; Sertorio, Mathieu  (2023). Impact of Multiple Beams on the FLASH Effect in Soft Tissue and Skin in Mice. International journal of radiation oncology, biology, physicsMore Information

Zou, Wei; Zhang, Rongxiao; Schüler, Emil; Taylor, Paige A; Mascia, Anthony E; Diffenderfer, Eric S; Zhao, Tianyu; Ayan, Ahmet S; Sharma, Manju; Yu, Shu-Jung; Lu, Weiguo; Bosch, Walter R; Tsien, Christina; Surucu, Murat; Pollard-Larkin, Julianne M; Schuemann, Jan; Moros, Eduardo G; Bazalova-Carter, Magdalena; Gladstone, David J; Li, Heng; Simone, Charles B; Petersson, Kristoffer; Kry, Stephen F; Maity, Amit; Loo, Billy W; Dong, Lei; Maxim, Peter G; Xiao, Ying; Buchsbaum, Jeffrey C  (2023). Framework for Quality Assurance of Ultrahigh Dose Rate Clinical Trials Investigating FLASH Effects and Current Technology Gaps. International journal of radiation oncology, biology, physics, 116 (5) , 1202-1217More Information

Nelson, Bailey; Meier, Teresa; Zhang, Yin; Wang, Kyle; Mascia, Anthony E; Paquette, Ian; Thompson, Earl; Rafferty, Janice; Snyder, Jonathan; Olowokure, Olugbenga; Sohal, Davendra; Kharofa, Jordan  (2023). Feasibility Trial of Intensity Modulated Proton Therapy to Reduce Toxicity in Anal Cancer Patients. American journal of clinical oncology, 46 (7) , 293-299More Information

Mascia, Anthony E; Daugherty, Emily C; Breneman, John C  (2023). FLASH Radiotherapy in a Value-Based Health Care Environment-Reply. JAMA oncology, 9 (5) , 727More Information

Lourenço, Ana; Subiel, Anna; Lee, Nigel; Flynn, Sam; Cotterill, John; Shipley, David; Romano, Francesco; Speth, Joe; Lee, Eunsin; Zhang, Yongbin; Xiao, Zhiyan; Mascia, Anthony; Amos, Richard A; Palmans, Hugo; Thomas, Russell  (2023). Absolute dosimetry for FLASH proton pencil beam scanning radiotherapy. Scientific reports, 13 (1) , 2054More Information

Academic - Cincinnati Children's Hospital
UC Health Proton Therapy Center
Liberty Township  Ohio, 45044
Phone: (513)517-0343
anthony.mascia@cchmc.org