Francis McCormack

Francis X. McCormack , MD

Professor

Division Chief, Pulmonary Critical Care and Sleep Medicine; Gordon and Helen Hughes Taylor Chair

Internal Medicine
Medical Sciences Building 6165
231 Albert Sabin Way, ML 0564
Cincinnati, Ohio 45267
Phone 513-558-4831
Fax 513-558-4858
Email frank.mccormack@uc.edu

Professional Summary

We conduct both basic and clinical research programs, focused primarily on development of pathogenesis-driven molecular diagnostics and therapeutics for rare lung diseases. We are an integral part of the Translational Pulmonary Science Center, which is a collaborative project between pulmonary groups at UC and CCHMC, the Rare Lung Diseases Consortium (PIs Trapnell and McCormack), an NIH and NCATs supported platform for conducting studies in rare lung disease.

In our basic research, all projects have a human clinic trial on the horizon, at least conceptually. The laboratory has used mouse models of pulmonary Langerhans cell histiocytosis, Hermansky Pudlak syndrome,  lymphangioleiomyomatosis, and pulmonary alveolar microlithiasis in preclinical studies to determine mechanisms of alveolar homeostasis in health and disease. We are also interested in the role of pulmonary airway cells, collectins and lung epithelial cells in innate immune defense against inhaled bacteria, mycobacteria, fungi and viruses, especially (and most recently) influenza.

Our clinical research is focused on investigator-initiated, multicenter, international randomized trials for lymphangioleiomyomatosis, one of which recently led to discovery of an effective treatment and to FDA approval. We are optimistic that our laboratory findings will support the design and execution of trials of phosphate restriction for pulmonary alveolar microlithiasis, BRAF inhibitors for pulmonary Langerhans cell  histiocytosis, KGF treatment for pulmonary non tuberculous mycobacterial disease, and mTOR inhibitor prophylaxis and therapy for  influenza.

Education

Bachelor's Degree (magna cum laude): University of California, San Diego 1978 (Chemistry)

Medical Degree: University of Texas Medical Branch 1982 (Medicine)

Internship and Residency : University of Michigan 1985 (Internal Medicine )

Chief Residency : University of Michigan 1986 (Internal Medicine )

Clinical Fellowship : University of Colorado Health Sciences Center 1987 (Pulmonary and Critical Care Medicine )

Research Fellowship National : Jewish Center and Medicine University of Colorado Health Sciences Center 1989 (Medicine, Pulmonary and Critical Care )

Certifications

American Board of Internal Medicine (Certification Date: 09-11-1985 )

American Board of Internal Medicine (Pulmonary Disease) (Certification Date: 11-01-1988 )

Clinical Interests

Critical Care Medicine

Pulmonary Disease

Lung Disease

Rare Lung Disease

Sarcoidosis

Asbestosis

Bronchiolitis

Chronic Cough

Dyspnea

Histoplasmosis

Idiopathic Pulmonary Fibrosis

Legionnaires' Disease (Legionellosis)

Lymphangioleiomyomatosis (LAM)

Lymphatic Disease

Pleurisy

Pneumonia

Pneumonitis

Pulmonary Fibrosis

Pulmonary Sarcoidosis

Respiration Disorders

Respiratory Syncytial Virus (RSV)

Respiratory Tract Disease

Respiratory Tract Infections

Shortness of Breath

Thoracic Disease

Tuberculosis

Whooping Cough (Pertussis)

Specialities

Critical Care Medicine

Internal Medicine

Research and Practice Interests

Basic laboratory focus
1. The structure/function relationships of surfactant proteins, surfactant homeostasis, surfactant proteins (collectins) in host defense. 
2. Mechanisms of pulmonary fibrosis
3. The role of the pulmonary epithelium in influenza infection
4. Molecular  and cellular basis of pulmonary alveolar microlithiasis
5. Pathogenesis of pulmonary Langerhans histiocytosis

Clinical research focus
1. Genetic interstitial lung disease
2. Lymphangioleiomyomatosis

Positions and Work Experience

2006 - Gordon and Helen Hughes Taylor Chair, University of Cincinnati,

2005 - Professor, Division of Pulmonary and Critical Care Medicine, University of Cincinnati,

2002 - Associate Professor of Medicine (with tenure), Division of Pulmonary and Critical Care Medicine, University of Cincinnati,

1999 - Associate Professor of Medicine, Division of Pulmonary and Critical Care Medicine, University of Cincinnati,

1996 - Staff Physician, Pulmonary Section, Cincinnati Veterans Administration Medical Center,

1994 - Assistant Professor of Medicine, Division of Pulmonary and Critical Care Medicine, University of Cincinnati,

1990 - Assistant Professor of Medicine, University of Colorado,

1990 - Staff Physician, National Jewish Medical Center,

1989 - Instructor, Department of Medicine, National Jewish Center and Division of Pulmonary and Critical Care Medicine, University of Colorado,

Research Support

Grant: #2 R13 HL093774-07 Investigators:McCormack, Francis 04-01-2014 -03-31-2015 National Heart, Lung and Blood Institute 2014 LAM Foundation International Lymphangioleiomyomatosis Research Conference Role:PI $25,000.00 Awarded Level:Federal

Grant: #Shriners 2014 Investigators:McCormack, Francis 01-01-2014 -12-31-2014 Shriners Hospitals for Children - Cincinnati Burn Induced Lung Injury and Infection Role:PI $114,273.00 Active Level:Private Non-Profit

Grant: #101811297/1UH2TR000961 Investigators:McCormack, Francis 06-18-2013 -05-31-2016 National Center for Advancing Translational Sciences Therapeutic Strategy for Lymphangioleiomymoatosis (LAM) and Tuberous Sclerosis Role:PI $173,069.00 Active Level:Federal

Grant: #R13HL093774 Investigators:McCormack, Francis 04-01-2013 -03-31-2014 National Heart, Lung and Blood Institute 2013 LAM Symposium Role:PI $18,000.00 Active Level:Federal

Grant: #85120 Investigators:McCormack, Francis 01-01-2013 -12-31-2017 Shriners Hospitals for Children - Cincinnati Burn Induced Lung Injury and Infection Role:PI $83,611.00 Active Level:Private Non-Profit

Grant: #2R13HL093774 Investigators:McCormack, Francis 04-15-2012 -03-31-2013 National Heart, Lung and Blood Institute 2012 International LAMS Research Conference Role:PI $19,000.00 Closed Level:Federal

Grant: #R13HL093774 Investigators:McCormack, Francis 06-01-2011 -04-11-2012 National Heart, Lung and Blood Institute 2011 International LAM Research Conference Role:PI $25,000.00 Closed Level:Federal

Grant: #W81XWH-10-1-0885 Investigators:Kinder, Brent; McCormack, Francis; Shukla, Rakesh 09-15-2010 -10-14-2013 Department of the Army Medical Research and Materiel Command LAM Clinics Research Network Role:PI $1,103,808.00 Active Level:Federal

Grant: #R13 HL093774 Investigators:McCormack, Francis 04-09-2010 -05-31-2012 National Heart, Lung and Blood Institute 2010 LAM Foundation International Research Conference Role:PI $25,000.00 Closed Level:Federal

Grant: #K23 HL094532 Investigators:Kinder, Brent; McCormack, Francis; Ridgway, William; Shukla, Rakesh 02-01-2010 -01-31-2015 National Heart, Lung and Blood Institute Undifferentiated Corrective Tissue-Associated Interstital Role:Collaborator $285,772.00 Closed Level:Federal

Grant: #RA 207670NGQAI083222 Investigators:McCormack, Francis 09-30-2009 -08-31-2011 National Institute of Allergy and Infectious Diseases Collectins and Innate Defense Against Inhaled Pathogens Role:PI $274,562.00 Closed Level:Federal

Grant: #3772-5 (Core B) / P01 AI083222 Investigators:McCormack, Francis 09-01-2009 -08-31-2012 National Institute of Allergy and Infectious Diseases Core B SP-A Molecular Biology, Protein, and Chemistry Role:PI $293,106.00 Closed Level:Federal

Grant: #3772-5 (Project 3) / P01 AI083222 Investigators:McCormack, Francis 09-01-2009 -08-31-2012 National Institute of Allergy and Infectious Diseases Modulation of Collection-Orchestrated Innate Immune Response Role:PI $524,380.00 Closed Level:Federal

Grant: #SRS 006945 Investigators:McCormack, Francis 07-27-2009 -07-31-2013 Wyeth-Ayerst Laboratories Rapamune Drug Study Role:PI $50,000.00 Active Level:Industry

Investigators:FX McCormack 09-2008 -04-2012 Veteran's Administration Merit Award Pulmonary Epithelial Innate Immune Defenses Role:PI $134,900 (annual amount)

Grant: #R13 HL093774 Investigators:McCormack, Francis; Thomas, George 04-04-2008 -04-08-2011 National Heart, Lung and Blood Institute 2008 LAM Research Conference Role:PI $45,000.00 Closed Level:Federal

Grant: #R01-FD003362 Investigators:McCormack, Francis 09-30-2007 -06-30-2011 Food and Drug Administration Phase 3 Trial of Sirolimus in Lymphangioleiomyatosis, IND 71,340-12/7/2004 Role:PI $1,046,709.00 Closed Level:Federal

Investigators:FX McCormack 09-14-2007 -09-14-2010 FDA R01 The MILES Trial Role:PI $250,000 (annual amount)

Grant: #R13 HL088920 Investigators:McCormack, Francis 04-01-2007 -03-31-2008 National Heart, Lung and Blood Institute 2007 LAM Foundation Lymphangioleiomyomatosis International Research Conference Role:PI $24,750.00 Closed Level:Federal

Grant: #1 R13 HL086443-01 Investigators:McCormack, Francis 03-31-2006 -04-02-2006 National Heart, Lung and Blood Institute Lymphangioleiomyomatosis Research Conference 2006 Role:PI $20,000.00 Closed Level:Federal

Grant: #CCHMC 349 / R01 HL058795 Investigators:McCormack, Francis 02-13-2004 -01-31-2009 National Heart, Lung and Blood Institute Surfactant Protein A and Lung Disease Role:PI $119,059.00 Closed Level:Federal

Grant: #5-U54-RR-019498-02-A0-S0-E0 Investigators:McCormack, Francis 09-30-2003 -07-31-2009 National Center for Research Resources Rare Lung Disease - Clinical Research Network Role:PI $329,448.00 Closed Level:Federal

Grant: #U54 RR019498-01 Investigators:B Trapnell, FX McCormack 09-30-2003 -08-31-2008 NIH/ORD/NCRR Rare Lung Diseases Clinical Research Network Role:Co-Director $17,140 (annual amount)

Grant: #1-R21-CA-103486-01-A0-S0-E0 Investigators:McCormack, Francis 09-01-2003 -08-31-2005 National Cancer Institute Rapamycin for the Treatment of Renal Angiomyolipomas Role:PI $25,014.00 Closed Level:Federal

Investigators:McCormack, Francis 12-01-2001 -11-30-2006 National Heart, Lung and Blood Institute Novel Antioxidant Mechanisms of Surfactant Proteins Role:PI $1,668,954.00 Closed Level:Federal

Investigators:McCormack, Francis 05-01-2001 -04-30-2006 National Heart, Lung and Blood Institute Structure/Function Analyses of SP-B Role:PI $162,173.00 Closed Level:Federal

Grant: #5-R01-HL-61612-04-A0-S0-E0 Investigators:McCormack, Francis 12-01-1998 -11-30-2003 National Heart, Lung and Blood Institute Surfactant Protein-A in Pulmonary Host Defense Role:PI $720,482.00 Closed Level:Federal

Grant: #5-R01-HL-51990-05-A0-S0-E0 Investigators:McCormack, Francis 09-01-1994 -08-31-1999 National Heart, Lung and Blood Institute Surfactant Proteins in Pathogenesis of Tuberculosis Role:PI $361,245.00 Closed Level:Federal

Grant: #135458 & 133851 / U54 HL127672 Investigators:McCormack, Francis 09-18-2014 -07-31-2019 National Heart, Lung and Blood Institute RLDC Molecular Pathway-Driven Diagnostis and Therapeutics for Rare Lung Diseases Role:PI $176,932.00 Active Level:Federal

Grant: #R01 HL127455 Investigators:Amlal, Hassane; McCormack, Francis 04-01-2015 -03-31-2019 National Heart, Lung and Blood Institute Pathogenesis-Driven Therapeutic Development for Pulmonary Alveolar Microlithiasis Role:PI $409,364.00 Awarded Level:Federal

Grant: #R13 HL093774 Investigators:McCormack, Francis 03-15-2015 -02-29-2016 National Heart, Lung and Blood Institute 2015 LAM Foundation International Lymphangioleiomyomatosis Conference Role:PI $25,000.00 Awarded Level:Federal

Grant: #SHRINERS 2015 Investigators:McCormack, Francis 01-01-2015 -12-31-2015 Shriners Hospitals for Children - Cincinnati Burn Induced Lung Injury and Infection Role:PI $262,513.00 Active Level:Private Non-Profit

Grant: #102184545 / UH3TR000961-02 Investigators:McCormack, Francis 09-01-2015 -08-31-2016 National Center for Advancing Translational Sciences Therapeutic Strategy for Lymphangioleiomymoatosis (LAM) and Tuberous Sclerosis Role:PI $115,739.96 Active Level:Federal

Grant: #Shriner's 2016 Investigators:McCormack, Francis 01-01-2016 -12-31-2016 Shriners Hospitals for Children - Cincinnati Burn Induced Lung Injury and Infection - Year 4 Role:PI $270,782.45 Awarded Level:Private Non-Profit

Grant: #R13 HL093774 Investigators:McCormack, Francis 07-05-2016 -06-30-2017 National Heart, Lung and Blood Institute 2016 LAM Foundation International Lymphangioleiomyomatosis Research Conference Role:PI $25,000.00 Active Level:Federal

Grant: #MIDAS / U54 HL127672 Investigators:McCormack, Francis 08-01-2015 -07-31-2016 National Heart, Lung and Blood Institute RLDC: Multicenter International Durability and Safety of Sirolimus in LAM Trial (MIDAS) Role:PI $3,850.00 Closed Level:Federal

Grant: #137508 / R21 HL133539 Investigators:McCormack, Francis 07-05-2016 -06-30-2018 National Heart, Lung and Blood Institute Integrative analysis of multi-omics data to target fibroblast activation in IPF Role:PI $18,962.00 Active Level:Federal

Grant: #U01HL131755 Investigators:McCormack, Francis 09-20-2016 -06-30-2021 National Heart, Lung and Blood Institute Multicenter Interventional Lymphangioleiomyomatosis Early Disease Trial (MILED)-CCC Role:PI $752,151.00 Awarded Level:Federal

Grant: #NEW Sub / 5UH3TR000961-03 Investigators:McCormack, Francis 09-01-2016 -08-31-2017 National Center for Advancing Translational Sciences Therapeutic Strategy for Lymphangioleiomymoatosis (LAM) and Tuberous Sclerosis Role:PI $153,138.04 Awarded Level:Federal

Grant: #115809 / U01 HL131022 Investigators:McCormack, Francis 09-21-2016 -08-31-2019 National Heart, Lung and Blood Institute The Molecular and Genetic Pathogenesis of LAM Role:PI $110,600.00 Active Level:Federal

Grant: #Shriners-2017 Investigators:McCormack, Francis 01-01-2017 -12-31-2017 Shriners Hospitals for Children - Cincinnati Burn Induced Lung Injury and Infection - Year 5 Role:PI $278,500.00 Awarded Level:Private Non-Profit

Grant: #CHMC / R01 HL134801 Investigators:McCormack, Francis 05-22-2017 -04-30-2022 National Heart, Lung and Blood Institute WT1 Regulation of Pulmonary Fibrosis Role:PI $9,518.00 Active Level:Federal

Grant: #R34 HL138235 Investigators:Gupta, Nishant; McCormack, Francis 07-01-2017 -06-30-2020 National Heart, Lung and Blood Institute Resveratrol and Sirolimus in LAM Trial (RESULT) Role:Collaborator $250,025.00 Active Level:Federal

Grant: #R01 HL138481 Investigators:Gupta, Nishant; Ho, Shuk Mei; McCormack, Francis; Yu, Jane 08-01-2017 -06-30-2020 National Heart, Lung and Blood Institute Targeting prostaglandin biosynthesis and action in lymphangioleiomyomatosis Role:Collaborator $651,071.00 Awarded Level:Federal

Grant: #2 R13 HL093774-010 Investigators:McCormack, Francis 11-01-2017 -10-31-2018 National Heart, Lung and Blood Institute 2017 LAM Foundation International Lymphangioleiomyomatosis Research Conference Role:PI $25,000.00 Active Level:Federal

Grant: #139257 / W81XWH-17- 1-0666 Investigators:Desai, Pankaj; McCormack, Francis 09-30-2017 -09-29-2018 Department of the Army Medical Research Acquisition Activity Therapeutic Benefit of HSP90 Inhibition in Pulmonary Fibrosis Role:PI $43,149.00 Awarded Level:Federal

Grant: #R01 HL135122 Investigators:Borchers, Michael; McCormack, Francis; Yu, Jane 12-07-2017 -11-30-2021 National Heart, Lung and Blood Institute Pulmonary Epithelial Dynamics and Innate Host Defense Role:PI $506,717.00 Active Level:Federal

Grant: #LAM0129S06-18 Investigators:McCormack, Francis 06-01-2018 -05-31-2020 Lymphangioleiomyomatosis Foundation (LAM) Single Cell RNA Sequencing in LAM Role:PI $80,000.00 Active Level:Private Non-Profit

Grant: #994-SUB CLOVERS / U01HL123009 Investigators:Hudock, Kristin; McCormack, Francis 11-01-2017 -04-30-2021 National Heart, Lung and Blood Institute CLOVERS: Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis Role:Collaborator $179,707.70 Active Level:Federal

Grant: #LAM0132PB07-18 Investigators:Cole, Adam; Gupta, Nishant; McCormack, Francis 09-01-2018 -08-31-2021 Lymphangioleiomyomatosis Foundation (LAM) Impact of menstrual cycle related variation in lung function on disease progression in LAM Role:Collaborator $10,000.00 Awarded Level:Private Non-Profit

Grant: #EH18-254 / R01HD096209 Investigators:McCormack, Francis 04-11-2019 -03-31-2023 National Institute of Child Health and Human Development Prevention of Preterm Birth Using the Collectin Surfactant Protein A (SP-A) Role:PI $56,566.31 Awarded Level:Federal

Grant: #CP192849 Investigators:McCormack, Francis 05-01-2019 -05-01-2021 Pfizer, Inc. A population-based chort study to monitor safety and effectiveness of sirolimus in patients with sporadic lymphangioleimyomatosis Role:PI $250,000.00 Awarded Level:Industry

Grant: #139257 / W81XWH-17-1-0666 (011239-yr1) Investigators:Desai, Pankaj; McCormack, Francis 10-01-2018 -09-30-2019 Department of the Army Medical Research Acquisition Activity Therapeutic Benefit of HSP90 Inhibition in Pulmonary Fibrosis Role:PI $44,241.16 Active Level:Federal

Grant: #W81XWH-20-1-0736 Investigators:McCormack, Francis; Soleimani, Manoocher; Yu, Jane 09-01-2020 -08-31-2023 Department of the Army Medical Research Acquisition Activity Dysregulation of sphingolipid metabolism and actions in tuberous sclerosis complex Role:Collaborator $722,250.00 Awarded Level:Federal

Grant: #122805 / U01HL131022 Investigators:McCormack, Francis 03-01-2020 -02-28-2025 National Heart, Lung and Blood Institute The Molecular and Genetic Pathogenesis of LAM Role:PI $561,749.99 Active Level:Federal

Grant: #CCHMC / R01HL153045 Investigators:McCormack, Francis; Yu, Jane 07-21-2020 -06-30-2024 National Heart, Lung and Blood Institute Uterine signaling networks in the pathogenesis of pulmonary lymphangioleiomyomatosis (LAM). Role:Collaborator $386,106.84 Active Level:Federal

Grant: #MIDAS Agreement Investigators:McCormack, Francis 08-01-2020 -07-31-2021 Lymphangioleiomyomatosis Foundation (LAM) MIDAS Role:PI $9,240.00 Awarded Level:Private Non-Profit

Publications

Peer Reviewed Publications

Safi, Fadi; Gupta, Anita; Adams, Denise; Anandan, Vasuki; McCormack, Francis X; Assaly, Ragheb (2014. ) Kaposiform lymphangiomatosis, a newly characterized vascular anomaly presenting with hemoptysis in an adult woman.Annals of the American Thoracic Society, , 11 (1 ) ,92-5 More Information

Nikolaidis, Nikolaos M; White, Mitchell R; Allen, Kimberly; Tripathi, Shweta; Qi, Li; McDonald, Barbara; Taubenberger, Jeffery; Seaton, Barbara A; McCormack, Francis X; Crouch, Erika C; Hartshorn, Kevan L (2014. ) Mutations flanking the carbohydrate binding site of surfactant protein D confer antiviral activity for pandemic influenza A viruses.American journal of physiology. Lung cellular and molecular physiology, , 306 (11 ) ,L1036-44 More Information

Gardner, Jason C; Noel, John G; Nikolaidis, Nikolaos M; Karns, Rebekah; Aronow, Bruce J; Ogle, Cora K; McCormack, Francis X (2014. ) G-CSF drives a posttraumatic immune program that protects the host from infection.Journal of immunology (Baltimore, Md. : 1950), , 192 (5 ) ,2405-17 More Information

Cundiff, William B; McCormack, Francis X; Wikenheiser-Brokamp, Kathryn; Starnes, Sandra; Kotloff, Robert; Benzaquen, Sadia (2014. ) Successful management of a chronic, refractory bronchopleural fistula with endobronchial valves followed by talc pleurodesis.American journal of respiratory and critical care medicine, , 189 (4 ) ,490-1 More Information

Zafar, Muhammad A; McCormack, Francis X; Rahman, Shahid; Tencza, Christian; Wikenheiser-Brokamp, Kathryn A; Young, Lisa R; Shizukuda, Yukitaka; Elwing, Jean M (2013. ) Pulmonary vascular shunts in exercise-intolerant patients with lymphangioleiomyomatosis.American journal of respiratory and critical care medicine, , 188 (9 ) ,1167-70 More Information

Krueger, Darcy A; Northrup, Hope (2013. ) Tuberous sclerosis complex surveillance and management: recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference.Pediatric neurology, , 49 (4 ) ,255-65 More Information

Safi, Fadi; Gupta, Anita; Adams, Denise; Anandan, Vasuki; McCormack, Francis X; Assaly, Ragheb (2013. ) Kaposiform Lymphangiomatosis, a Newly Characterized Vascular Anomaly Presenting with Hemoptysis in an Adult Woman.Annals of the American Thoracic Society, , More Information

Northrup, Hope; Krueger, Darcy A (2013. ) Tuberous sclerosis complex diagnostic criteria update: recommendations of the 2012 Iinternational Tuberous Sclerosis Complex Consensus Conference.Pediatric neurology, , 49 (4 ) ,243-54 More Information

Gupta, Nishant; McCormack, Francis X (2013. ) Pulmonary alveolar microlithiasis.American journal of respiratory and critical care medicine, , 188 (7 ) ,e11-2 More Information

Czyzyk-Krzeska, Maria F; McCormack, Francis X (2013. ) Birt-Hogg-Dubé syndrome.Familial cancer, , 12 (3 ) ,355-6 More Information

Gupta, Nishant; Seyama, Kuniaki; McCormack, Francis X (2013. ) Pulmonary manifestations of Birt-Hogg-Dubé syndrome.Familial cancer, , 12 (3 ) ,387-96 More Information

McCormack, Francis X; Travis, William D; Colby, Thomas V; Henske, Elizabeth P; Moss, Joel (2013. ) Reply: Characterization of lymphangioleiomyomatosis as a neoplastic disease.American journal of respiratory and critical care medicine, , 188 (3 ) ,398-9 More Information

Cudzilo, Corey J; Szczesniak, Rhonda D; Brody, Alan S; Rattan, Mantosh S; Krueger, Darcy A; Bissler, John J; Franz, David N; McCormack, Francis X; Young, Lisa R (2013. ) Lymphangioleiomyomatosis screening in women with tuberous sclerosis.Chest, , 144 (2 ) ,578-85 More Information

Young, Lisa R; Lee, Hye-Seung; Inoue, Yoshikazu; Moss, Joel; Singer, Lianne G; Strange, Charlie; Nakata, Koh; Barker, Alan F; Chapman, Jeffrey T; Brantly, Mark L; Stocks, James M; Brown, Kevin K; Lynch, Joseph P; Goldberg, Hilary J; Downey, Gregory P; Swigris, Jeffrey J; Taveira-Dasilva, Angelo M; Krischer, Jeffrey P; Trapnell, Bruce C; McCormack, Francis X (2013. ) Serum VEGF-D concentration as a biomarker of lymphangioleiomyomatosis severity and treatment response: a prospective analysis of the Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus (MILES) trial.The lancet. Respiratory medicine, , 1 (6 ) ,445-452 More Information

McCormack, Francis X; Wilmott, Clay; Young, Lisa R; Wikenheiser-Brokamp, Kathryn (2013. ) An atoll variant that mocks.American journal of respiratory and critical care medicine, , 188 (1 ) ,110 More Information

Swigris, Jeffrey J; Lee, Hye-Seung; Cohen, Marsha; Inoue, Yoshikazu; Moss, Joel; Singer, Lianne G; Young, Lisa R; McCormack, Francis X (2013. ) St. George's Respiratory Questionnaire has longitudinal construct validity in lymphangioleiomyomatosis.Chest, , 143 (6 ) ,1671-8 More Information

Oprescu, N; McCormack, F X; Byrnes, S; Kinder, B W (2013. ) Clinical predictors of mortality and cause of death in lymphangioleiomyomatosis: a population-based registry.Lung, , 191 (1 ) ,35-42 More Information

McCormack, Francis X; Travis, William D; Colby, Thomas V; Henske, Elizabeth P; Moss, Joel (2012. ) Lymphangioleiomyomatosis: calling it what it is: a low-grade, destructive, metastasizing neoplasm.American journal of respiratory and critical care medicine, , 186 (12 ) ,1210-2 More Information

Meraj, Riffat; Wikenheiser-Brokamp, Kathryn A; Young, Lisa R; Byrnes, Sue; McCormack, Francis X (2012. ) Utility of transbronchial biopsy in the diagnosis of lymphangioleiomyomatosis.Frontiers of medicine, , 6 (4 ) ,395-405 More Information

Young, Lisa R; Gulleman, Peter M; Bridges, James P; Weaver, Timothy E; Deutsch, Gail H; Blackwell, Timothy S; McCormack, Francis X (2012. ) The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome.American journal of respiratory and critical care medicine, , 186 (10 ) ,1014-24 More Information

Henske, Elizabeth P; McCormack, Francis X (2012. ) Lymphangioleiomyomatosis - a wolf in sheep's clothing.The Journal of clinical investigation, , 122 (11 ) ,3807-16 More Information

Meraj, Riffat; Wikenheiser-Brokamp, Kathryn A; Young, Lisa R; McCormack, Francis X (2012. ) Lymphangioleiomyomatosis: new concepts in pathogenesis, diagnosis, and treatment.Seminars in respiratory and critical care medicine, , 33 (5 ) ,486-97 More Information

Crouch, Erika; Nikolaidis, Nikolaos; McCormack, Francis X; McDonald, Barbara; Allen, Kimberly; Rynkiewicz, Michael J; Cafarella, Tanya M; White, Mitchell; Lewnard, Kara; Leymarie, Nancy; Zaia, Joseph; Seaton, Barbara A; Hartshorn, Kevan L (2011. ) Mutagenesis of surfactant protein D informed by evolution and x-ray crystallography enhances defenses against influenza A virus in vivo.The Journal of biological chemistry, , 286 (47 ) ,40681-92 More Information

Seaman, Danielle M; Meyer, Cristopher A; Gilman, Matthew D; McCormack, Francis X (2011. ) Diffuse Cystic Lung Disease at High-Resolution CT.AJR. American journal of roentgenology, , 196 (6 ) ,1305-11 More Information

Wu, Huixing; Suzuki, Takuji; Carey, Brenna; Trapnell, Bruce C; McCormack, Francis X (2011. ) Keratinocyte growth factor augments pulmonary innate immunity through epithelium-driven, GM-CSF-dependent paracrine activation of alveolar macrophages.The Journal of biological chemistry, , 286 (17 ) ,14932-40 More Information

McCormack, Francis X; Inoue, Yoshikazu; Moss, Joel; Singer, Lianne G; Strange, Charlie; Nakata, Koh; Barker, Alan F; Chapman, Jeffrey T; Brantly, Mark L; Stocks, James M; Brown, Kevin K; Lynch, Joseph P; Goldberg, Hilary J; Young, Lisa R; Kinder, Brent W; Downey, Gregory P; Sullivan, Eugene J; Colby, Thomas V; McKay, Roy T; Cohen, Marsha M; Korbee, Leslie; Taveira-DaSilva, Angelo M; Lee, Hye-Seung; Krischer, Jeffrey P; Trapnell, Bruce C (2011. ) Efficacy and safety of sirolimus in lymphangioleiomyomatosis.The New England journal of medicine, , 364 (17 ) ,1595-606 More Information

Hagaman, Jared T; Panos, Ralph J; McCormack, Francis X; Thakar, Charuhas V; Wikenheiser-Brokamp, Kathryn A; Shipley, Ralph T; Kinder, Brent W (2011. ) Vitamin D deficiency and reduced lung function in connective tissue-associated interstitial lung diseases.Chest, , 139 (2 ) ,353-60 More Information

Shang, Feifei; Rynkiewicz, Michael J; McCormack, Francis X; Wu, Huixing; Cafarella, Tanya M; Head, James F; Seaton, Barbara A (2011. ) Crystallographic complexes of surfactant protein A and carbohydrates reveal ligand-induced conformational change.The Journal of biological chemistry, , 286 (1 ) ,757-65 More Information

Franz, D N; Bissler, J J; McCormack, F X (2010. ) Tuberous sclerosis complex: neurological, renal and pulmonary manifestations.Neuropediatrics, , 41 (5 ) ,199-208 More Information

Young, Lisa R; Vandyke, Rhonda; Gulleman, Peter M; Inoue, Yoshikazu; Brown, Kevin K; Schmidt, Laura S; Linehan, W Marston; Hajjar, Fuad; Kinder, Brent W; Trapnell, Bruce C; Bissler, John J; Franz, David N; McCormack, Francis X (2010. ) Serum vascular endothelial growth factor-D prospectively distinguishes lymphangioleiomyomatosis from other diseases.Chest, , 138 (3 ) ,674-81 More Information

Hagaman, Jared T; Schauer, Daniel P; McCormack, Francis X; Kinder, Brent W (2010. ) Screening for lymphangioleiomyomatosis by high-resolution computed tomography in young, nonsmoking women presenting with spontaneous pneumothorax is cost-effective.American journal of respiratory and critical care medicine, , 181 (12 ) ,1376-82 More Information

Kinder, Brent W; Sherman, A C; Young, L R; Hagaman, J T; Oprescu, N; Byrnes, S; McCormack, Francis X (2010. ) Predictors for clinical trial participation in the rare lung disease lymphangioleiomyomatosis.Respiratory medicine, , 104 (4 ) ,578-83 More Information

Kinder, Brent; McCormack, Francis X (2010. ) Clinical trials for rare lung diseases: lessons from lymphangioleiomyomatosis.Lymphatic research and biology, , 8 (1 ) ,71-9 More Information

Seaton, Barbara A; Crouch, Erika C; McCormack, Francis X; Head, James F; Hartshorn, Kevan L; Mendelsohn, Richard (2010. ) Review: Structural determinants of pattern recognition by lung collectins.Innate immunity, , 16 (3 ) ,143-50 More Information

Johnson, S R; Cordier, J F; Lazor, R; Cottin, V; Costabel, U; Harari, S; Reynaud-Gaubert, M; Boehler, A; Brauner, M; Popper, H; Bonetti, F; Kingswood, C (2010. ) European Respiratory Society guidelines for the diagnosis and management of lymphangioleiomyomatosis.The European respiratory journal, , 35 (1 ) ,14-26 More Information

Hagaman, Jared T; Ferguson, Bryce; Meyer, Cris; Wang, Jiang; McCormack, Francis X; Nath, Amaresh (2010. ) Endobronchial Carcinoid Tumor in an HIV-infected Patient.Journal of bronchology & interventional pulmonology, , 17 (2 ) ,174-6 More Information

Young, Lisa R; Franz, David N; Nagarkatte, Preeti; Fletcher, Christopher D M; Wikenheiser-Brokamp, Kathryn A; Galsky, Matthew D; Corbridge, Thomas C; Lam, Anna P; Gelfand, Michael J; McCormack, Francis X (2009. ) Utility of [18F]2-fluoro-2-deoxyglucose-PET in sporadic and tuberous sclerosis-associated lymphangioleiomyomatosis.Chest, , 136 (3 ) ,926-33 More Information

Kinder, Brent W; Brown, Kevin K; McCormack, Francis X; Ix, Joachim H; Kervitsky, Alma; Schwarz, Marvin I; King, Talmadge E (2009. ) Serum surfactant protein-A is a strong predictor of early mortality in idiopathic pulmonary fibrosis.Chest, , 135 (6 ) ,1557-63 More Information

Schmithorst, Vincent J; Altes, Talissa A; Young, Lisa R; Franz, David N; Bissler, John J; McCormack, Francis X; Dardzinski, Bernard J; Brody, Alan S (2009. ) Automated algorithm for quantifying the extent of cystic change on volumetric chest CT: initial results in Lymphangioleiomyomatosis.AJR. American journal of roentgenology, , 192 (4 ) ,1037-44 More Information

Gil, Malgorzata; McCormack, Francis X; Levine, Ann Marie (2009. ) Surfactant protein A modulates cell surface expression of CR3 on alveolar macrophages and enhances CR3-mediated phagocytosis.The Journal of biological chemistry, , 284 (12 ) ,7495-504 More Information

McCormack, Francis X (2008. ) Lymphangioleiomyomatosis: a clinical update.Chest, , 133 (2 ) ,507-16 More Information

Young, Lisa R; Inoue, Yoshikazu; McCormack, Francis X (2008. ) Diagnostic potential of serum VEGF-D for lymphangioleiomyomatosis.The New England journal of medicine, , 358 (2 ) ,199-200 More Information

Bissler, John J; McCormack, Francis X; Young, Lisa R; Elwing, Jean M; Chuck, Gail; Leonard, Jennifer M; Schmithorst, Vincent J; Laor, Tal; Brody, Alan S; Bean, Judy; Salisbury, Shelia; Franz, David N (2008. ) Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis.The New England journal of medicine, , 358 (2 ) ,140-51 More Information

Ali, Naeem A; O'Brien, James M; Hoffmann, Stephen P; Phillips, Gary; Garland, Allan; Finley, James C W; Almoosa, Khalid; Hejal, Rana; Wolf, Karen M; Lemeshow, Stanley; Connors, Alfred F; Marsh, Clay B (2008. ) Acquired weakness, handgrip strength, and mortality in critically ill patients.American journal of respiratory and critical care medicine, , 178 (3 ) ,261-8 More Information

Young, Lisa R; Pasula, Rajamouli; Gulleman, Peter M; Deutsch, Gail H; McCormack, Francis X (2007. ) Susceptibility of Hermansky-Pudlak mice to bleomycin-induced type II cell apoptosis and fibrosis.American journal of respiratory cell and molecular biology, , 37 (1 ) ,67-74 More Information

McCormack, Francis X; Moss, Joel (2007. ) S-LAM in a man?.American journal of respiratory and critical care medicine, , 176 (1 ) ,3-5 More Information

Zhang, Shiping; McCormack, Francis X; Levesque, Roger C; O'Toole, George A; Lau, Gee W (2007. ) The flagellum of Pseudomonas aeruginosa is required for resistance to clearance by surfactant protein A.PloS one, , 2 (6 ) ,e564 More Information

Juvet, Stephen C; McCormack, Francis X; Kwiatkowski, David J; Downey, Gregory P (2007. ) Molecular pathogenesis of lymphangioleiomyomatosis: lessons learned from orphans.American journal of respiratory cell and molecular biology, , 36 (4 ) ,398-408 More Information

Byrnes, Abigail B; McCormack, Francis X; Diers, Tiffiny; Jazieh, Abdul-Rahman (2007. ) The resident scholar program: a research training opportunity for internal medicine house staff.Journal of cancer education : the official journal of the American Association for Cancer Education, , 22 (1 ) ,47-9 More Information

Pollock-BarZiv, Stacey; Cohen, Marsha M; Downey, Gregory P; Johnson, Simon R; Sullivan, Eugene; McCormack, Francis X (2007. ) Air travel in women with lymphangioleiomyomatosis.Thorax, , 62 (2 ) ,176-80 More Information

Kingma, Paul S; Zhang, Liqian; Ikegami, Machiko; Hartshorn, Kevan; McCormack, Francis X; Whitsett, Jeffrey A (2006. ) Correction of pulmonary abnormalities in Sftpd-/- mice requires the collagenous domain of surfactant protein D.The Journal of biological chemistry, , 281 (34 ) ,24496-505 More Information

Zhang, Liqian; Ikegami, Machiko; Korfhagen, Thomas R; McCormack, Francis X; Yoshida, Mitsuhiro; Senior, Robert M; Shipley, J Michael; Shapiro, Steven D; Whitsett, Jeffrey A (2006. ) Neither SP-A nor NH2-terminal domains of SP-A can substitute for SP-D in regulation of alveolar homeostasis.American journal of physiology. Lung cellular and molecular physiology, , 291 (2 ) ,L181-90 More Information

Schlosser, A; Thomsen, T; Shipley, J M; Hein, P W; Brasch, F; Tornøe, I; Nielsen, O; Skjødt, K; Palaniyar, N; Steinhilber, W; McCormack, F X; Holmskov, U (2006. ) Microfibril-associated protein 4 binds to surfactant protein A (SP-A) and colocalizes with SP-A in the extracellular matrix of the lung.Scandinavian journal of immunology, , 64 (2 ) ,104-16 More Information

Almoosa, Khalid F; McCormack, Francis X; Sahn, Steven A (2006. ) Pleural disease in lymphangioleiomyomatosis.Clinics in chest medicine, , 27 (2 ) ,355-68 More Information

Almoosa, Khalid F; Ryu, Jay H; Mendez, Jose; Huggins, J Terrill; Young, Lisa R; Sullivan, Eugene J; Maurer, Janet; McCormack, Francis X; Sahn, Steven A (2006. ) Management of pneumothorax in lymphangioleiomyomatosis: effects on recurrence and lung transplantation complications.Chest, , 129 (5 ) ,1274-81 More Information

Young, Lisa R; Almoosa, Khalid F; Pollock-Barziv, Stacey; Coutinho, Meg; McCormack, Francis X; Sahn, Steven A (2006. ) Patient perspectives on management of pneumothorax in lymphangioleiomyomatosis.Chest, , 129 (5 ) ,1267-73 More Information

Young, Lisa R; Borchers, Michael T; Allen, Holly L; Gibbons, Reta S; McCormack, Francis X (2006. ) Lung-restricted macrophage activation in the pearl mouse model of Hermansky-Pudlak syndrome. Journal of immunology (Baltimore, Md. : 1950), , 176 (7 ) ,4361-8

Kuzmenko, Alexander I; Wu, Huixing; McCormack, Francis X (2006. ) Pulmonary collectins selectively permeabilize model bacterial membranes containing rough lipopolysaccharide.Biochemistry, , 45 (8 ) ,2679-85 More Information

McCormack, Francis X (2006. ) Lymphangioleiomyomatosis. MedGenMed : Medscape general medicine, , 8 (1 ) ,15

Ryu, Jay H; Moss, Joel; Beck, Gerald J; Lee, Jar-Chi; Brown, Kevin K; Chapman, Jeffrey T; Finlay, Geraldine A; Olson, Eric J; Ruoss, Stephen J; Maurer, Janet R; Raffin, Thomas A; Peavy, Hannah H; McCarthy, Kevin; Taveira-Dasilva, Angelo; McCormack, Francis X; Avila, Nilo A; Decastro, Rosamma M; Jacobs, Susan S; Stylianou, Mario; Fanburg, Barry L (2006. ) The NHLBI lymphangioleiomyomatosis registry: characteristics of 230 patients at enrollment.American journal of respiratory and critical care medicine, , 173 (1 ) ,105-11 More Information

Ryan, Marnie A; Akinbi, Henry T; Serrano, Alicia G; Perez-Gil, Jesus; Wu, Huixing; McCormack, Francis X; Weaver, Timothy E (2006. ) Antimicrobial activity of native and synthetic surfactant protein B peptides. Journal of immunology (Baltimore, Md. : 1950), , 176 (1 ) ,416-25

McCormack, Francis X (2006. ) New concepts in collectin-mediated host defense at the air-liquid interface of the lung.Respirology (Carlton, Vic.), , 11 Suppl ,S7-10 More Information

Zhang, Shiping; Chen, Yi; Potvin, Eric; Sanschagrin, Francois; Levesque, Roger C; McCormack, Francis X; Lau, Gee W (2005. ) Comparative signature-tagged mutagenesis identifies Pseudomonas factors conferring resistance to the pulmonary collectin SP-A.PLoS pathogens, , 1 (3 ) ,259-68 More Information

Beharka, Alison A; Crowther, Joy E; McCormack, Francis X; Denning, Gerene M; Lees, Jason; Tibesar, Eric; Schlesinger, Larry S (2005. ) Pulmonary surfactant protein A activates a phosphatidylinositol 3-kinase/calcium signal transduction pathway in human macrophages: participation in the up-regulation of mannose receptor activity. Journal of immunology (Baltimore, Md. : 1950), , 175 (4 ) ,2227-36

Kuzmenko, Alexander I; Wu, Huixing; Wan, Sijue; McCormack, Francis X (2005. ) Surfactant protein A is a principal and oxidation-sensitive microbial permeabilizing factor in the alveolar lining fluid.The Journal of biological chemistry, , 280 (27 ) ,25913-9 More Information

Schaeffer, Lyndsay M; McCormack, Francis X; Wu, Huixing; Weiss, Alison A (2004. ) Interactions of pulmonary collectins with Bordetella bronchiseptica and Bordetella pertussis lipopolysaccharide elucidate the structural basis of their antimicrobial activities.Infection and immunity, , 72 (12 ) ,7124-30 More Information

Schaeffer, Lyndsay M; McCormack, Francis X; Wu, Huixing; Weiss, Alison A (2004. ) Bordetella pertussis lipopolysaccharide resists the bactericidal effects of pulmonary surfactant protein A. Journal of immunology (Baltimore, Md. : 1950), , 173 (3 ) ,1959-65

Crowther, Joy E; Kutala, Vijay Kumar; Kuppusamy, Periannan; Ferguson, J Scott; Beharka, Alison A; Zweier, Jay L; McCormack, Francis X; Schlesinger, Larry S (2004. ) Pulmonary surfactant protein a inhibits macrophage reactive oxygen intermediate production in response to stimuli by reducing NADPH oxidase activity. Journal of immunology (Baltimore, Md. : 1950), , 172 (11 ) ,6866-74

Kuzmenko, A I; Wu, H; Bridges, J P; McCormack, F X (2004. ) Surfactant lipid peroxidation damages surfactant protein A and inhibits interactions with phospholipid vesicles.Journal of lipid research, , 45 (6 ) ,1061-8 More Information

Sietsema, Kathy E; McCormack, Francis X (2003. ) Lymphangioleiomyomatosis: insights about, and from, a rare disease.American journal of respiratory and critical care medicine, , 168 (12 ) ,1405-6 More Information

Head, James F; Mealy, Tanya R; McCormack, Francis X; Seaton, Barbara A (2003. ) Crystal structure of trimeric carbohydrate recognition and neck domains of surfactant protein A.The Journal of biological chemistry, , 278 (44 ) ,43254-60 More Information

McCormack, Francis X; Gibbons, Reta; Ward, Susan R; Kuzmenko, Alexander; Wu, Huixing; Deepe, George S (2003. ) Macrophage-independent fungicidal action of the pulmonary collectins.The Journal of biological chemistry, , 278 (38 ) ,36250-6 More Information

Rodriguez Capote, Karina; McCormack, Francis X; Possmayer, Fred (2003. ) Pulmonary surfactant protein-A (SP-A) restores the surface properties of surfactant after oxidation by a mechanism that requires the Cys6 interchain disulfide bond and the phospholipid binding domain.The Journal of biological chemistry, , 278 (23 ) ,20461-74 More Information

Wu, Huixing; Kuzmenko, Alexander; Wan, Sijue; Schaffer, Lyndsay; Weiss, Alison; Fisher, James H; Kim, Kwang Sik; McCormack, Francis X (2003. ) Surfactant proteins A and D inhibit the growth of Gram-negative bacteria by increasing membrane permeability.The Journal of clinical investigation, , 111 (10 ) ,1589-602 More Information

Karbowniczek, Magdalena; Astrinidis, Aristotelis; Balsara, Binaifer R; Testa, Joseph R; Lium, James H; Colby, Thomas V; McCormack, Francis X; Henske, Elizabeth Petri (2003. ) Recurrent lymphangiomyomatosis after transplantation: genetic analyses reveal a metastatic mechanism.American journal of respiratory and critical care medicine, , 167 (7 ) ,976-82 More Information

Chabot, Sophie; Salez, Laurent; McCormack, Francis X; Touqui, Lhousseine; Chignard, Michel (2003. ) Surfactant protein A inhibits lipopolysaccharide-induced in vivo production of interleukin-10 by mononuclear phagocytes during lung inflammation. American journal of respiratory cell and molecular biology, , 28 (3 ) ,347-53

Beharka, Alison A; Gaynor, Cecilia D; Kang, Byoung K; Voelker, Dennis R; McCormack, Francis X; Schlesinger, Larry S (2002. ) Pulmonary surfactant protein A up-regulates activity of the mannose receptor, a pattern recognition receptor expressed on human macrophages. Journal of immunology (Baltimore, Md. : 1950), , 169 (7 ) ,3565-73

Palaniyar, Nades; Zhang, Liquian; Kuzmenko, Alexander; Ikegami, Machiko; Wan, Sijue; Wu, Huixing; Korfhagen, Thomas R; Whitsett, Jeffrey A; McCormack, Francis X (2002. ) The role of pulmonary collectin N-terminal domains in surfactant structure, function, and homeostasis in vivo.The Journal of biological chemistry, , 277 (30 ) ,26971-9 More Information

Guillot, Loïc; Balloy, Viviane; McCormack, Francis X; Golenbock, Douglas T; Chignard, Michel; Si-Tahar, Mustapha (2002. ) Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4. Journal of immunology (Baltimore, Md. : 1950), , 168 (12 ) ,5989-92

McCormack, Francis X; Whitsett, Jeffrey A (2002. ) The pulmonary collectins, SP-A and SP-D, orchestrate innate immunity in the lung.The Journal of clinical investigation, , 109 (6 ) ,707-12 More Information

Malloy, Jaret L; Veldhuizen, Ruud A W; McCormack, Francis X; Korfhagen, Thomas R; Whitsett, Jeffery A; Lewis, James F (2002. ) Pulmonary surfactant and inflammation in septic adult mice: role of surfactant protein A.Journal of applied physiology (Bethesda, Md. : 1985), , 92 (2 ) ,809-16 More Information

McCormack, Francis; Brody, Alan; Meyer, Christopher; Leonard, Jennifer; Chuck, Gail; Dabora, Sandra; Sethuraman, Gopalan; Colby, Thomas V; Kwiatkowski, David J; Franz, David N (2002. ) Pulmonary cysts consistent with lymphangioleiomyomatosis are common in women with tuberous sclerosis: genetic and radiographic analysis. Chest, , 121 (3 Suppl ) ,61S

Ikegami, M; Elhalwagi, B M; Palaniyar, N; Dienger, K; Korfhagen, T; Whitsett, J A; McCormack, F X (2001. ) The collagen-like region of surfactant protein A (SP-A) is required for correction of surfactant structural and functional defects in the SP-A null mouse.The Journal of biological chemistry, , 276 (42 ) ,38542-8 More Information

Franz, D N; Brody, A; Meyer, C; Leonard, J; Chuck, G; Dabora, S; Sethuraman, G; Colby, T V; Kwiatkowski, D J; McCormack, F X (2001. ) Mutational and radiographic analysis of pulmonary disease consistent with lymphangioleiomyomatosis and micronodular pneumocyte hyperplasia in women with tuberous sclerosis. American journal of respiratory and critical care medicine, , 164 (4 ) ,661-8

Salez, L; Balloy, V; van Rooijen, N; Lebastard, M; Touqui, L; McCormack, F X; Chignard, M (2001. ) Surfactant protein A suppresses lipopolysaccharide-induced IL-10 production by murine macrophages. Journal of immunology (Baltimore, Md. : 1950), , 166 (10 ) ,6376-82

Palaniyar, N; Ikegami, M; Korfhagen, T; Whitsett, J; McCormack, F X (2001. ) Domains of surfactant protein A that affect protein oligomerization, lipid structure and surface tension. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, , 129 (1 ) ,109-27

Linke, M J; Harris, C E; Korfhagen, T R; McCormack, F X; Ashbaugh, A D; Steele, P; Whitsett, J A; Walzer, P D (2001. ) Immunosuppressed surfactant protein A-deficient mice have increased susceptibility to Pneumocystis carinii infection.The Journal of infectious diseases, , 183 (6 ) ,943-52 More Information

Bridges, J P; Davis, H W; Damodarasamy, M; Kuroki, Y; Howles, G; Hui, D Y; McCormack, F X (2000. ) Pulmonary surfactant proteins A and D are potent endogenous inhibitors of lipid peroxidation and oxidative cellular injury.The Journal of biological chemistry, , 275 (49 ) ,38848-55 More Information

Damodarasamy, M; Zhang, M; Dienger, K; McCormack, F X (2000. ) Two rat surfactant protein A isoforms arise by a novel mechanism that includes alternative translation initiation. Biochemistry, , 39 (33 ) ,10189-95

Palaniyar, N; McCormack, F X; Possmayer, F; Harauz, G (2000. ) Three-dimensional structure of rat surfactant protein A trimers in association with phospholipid monolayers. Biochemistry, , 39 (21 ) ,6310-6

Fisher, J H; Sheftelyevich, V; Ho, Y S; Fligiel, S; McCormack, F X; Korfhagen, T R; Whitsett, J A; Ikegami, M (2000. ) Pulmonary-specific expression of SP-D corrects pulmonary lipid accumulation in SP-D gene-targeted mice. American journal of physiology. Lung cellular and molecular physiology, , 278 (2 ) ,L365-73

Elhalwagi, B M; Zhang, M; Ikegami, M; Iwamoto, H S; Morris, R E; Miller, M L; Dienger, K; McCormack, F X (1999. ) Normal surfactant pool sizes and inhibition-resistant surfactant from mice that overexpress surfactant protein A. American journal of respiratory cell and molecular biology, , 21 (3 ) ,380-7

Ferguson, J S; Voelker, D R; McCormack, F X; Schlesinger, L S (1999. ) Surfactant protein D binds to Mycobacterium tuberculosis bacilli and lipoarabinomannan via carbohydrate-lectin interactions resulting in reduced phagocytosis of the bacteria by macrophages. Journal of immunology (Baltimore, Md. : 1950), , 163 (1 ) ,312-21

Yu, S H; McCormack, F X; Voelker, D R; Possmayer, F (1999. ) Interactions of pulmonary surfactant protein SP-A with monolayers of dipalmitoylphosphatidylcholine and cholesterol: roles of SP-A domains. Journal of lipid research, , 40 (5 ) ,920-9

McCormack, F X; Damodarasamy, M; Elhalwagi, B M (1999. ) Deletion mapping of N-terminal domains of surfactant protein A. The N-terminal segment is required for phospholipid aggregation and specific inhibition of surfactant secretion. The Journal of biological chemistry, , 274 (5 ) ,3173-81

Zhang, M; Damodarasamy, M; Elhalwagi, B M; McCormack, F X (1998. ) The longer isoform and Cys-1 disulfide bridge of rat surfactant protein A are not essential for phospholipid and type II cell interactions.Biochemistry, , 37 (47 ) ,16481-8 More Information

McCormack, F X (1998. ) Structure, processing and properties of surfactant protein A. Biochimica et biophysica acta, , 1408 (2-3 ) ,109-31

Borron, P; McCormack, F X; Elhalwagi, B M; Chroneos, Z C; Lewis, J F; Zhu, S; Wright, J R; Shepherd, V L; Possmayer, F; Inchley, K; Fraher, L J (1998. ) Surfactant protein A inhibits T cell proliferation via its collagen-like tail and a 210-kDa receptor. The American journal of physiology, , 275 (4 Pt 1 ) ,L679-86

Tsunezawa, W; Sano, H; Sohma, H; McCormack, F X; Voelker, D R; Kuroki, Y (1998. ) Site-directed mutagenesis of surfactant protein A reveals dissociation of lipid aggregation and lipid uptake by alveolar type II cells. Biochimica et biophysica acta, , 1387 (1-2 ) ,433-46

Smolarek, T A; Wessner, L L; McCormack, F X; Mylet, J C; Menon, A G; Henske, E P (1998. ) Evidence that lymphangiomyomatosis is caused by TSC2 mutations: chromosome 16p13 loss of heterozygosity in angiomyolipomas and lymph nodes from women with lymphangiomyomatosis.American journal of human genetics, , 62 (4 ) ,810-5 More Information

Pattanajitvilai, S; Kuroki, Y; Tsunezawa, W; McCormack, F X; Voelker, D R (1998. ) Mutational analysis of Arg197 of rat surfactant protein A. His197 creates specific lipid uptake defects. The Journal of biological chemistry, , 273 (10 ) ,5702-7

Sunkin, S M; Linke, M J; McCormack, F X; Walzer, P D; Stringer, J R (1998. ) Identification of a putative precursor to the major surface glycoprotein of Pneumocystis carinii. Infection and immunity, , 66 (2 ) ,741-6

McCormack, F X; Stewart, J; Voelker, D R; Damodarasamy, M (1997. ) Alanine mutagenesis of surfactant protein A reveals that lipid binding and pH-dependent liposome aggregation are mediated by the carbohydrate recognition domain.Biochemistry, , 36 (45 ) ,13963-71 More Information

McCormack, F X; Pattanajitvilai, S; Stewart, J; Possmayer, F; Inchley, K; Voelker, D R (1997. ) The Cys6 intermolecular disulfide bond and the collagen-like region of rat SP-A play critical roles in interactions with alveolar type II cells and surfactant lipids. The Journal of biological chemistry, , 272 (44 ) ,27971-9

McCormack, F X; Festa, A L; Andrews, R P; Linke, M; Walzer, P D (1997. ) The carbohydrate recognition domain of surfactant protein A mediates binding to the major surface glycoprotein of Pneumocystis carinii.Biochemistry, , 36 (26 ) ,8092-9 More Information

Elhalwagi, B M; Damodarasamy, M; McCormack, F X (1997. ) Alternate amino terminal processing of surfactant protein A results in cysteinyl isoforms required for multimer formation.Biochemistry, , 36 (23 ) ,7018-25 More Information

Blau, H; Riklis, S; Van Iwaarden, J F; McCormack, F X; Kalina, M (1997. ) Nitric oxide production by rat alveolar macrophages can be modulated in vitro by surfactant protein A. The American journal of physiology, , 272 (6 Pt 1 ) ,L1198-204

McCormack, F (1997. ) The structure and function of surfactant protein-A. Chest, , 111 (6 Suppl ) ,114S-119S

Gaynor, C D; McCormack, F X; Voelker, D R; McGowan, S E; Schlesinger, L S (1995. ) Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis by a direct interaction with human macrophages. Journal of immunology (Baltimore, Md. : 1950), , 155 (11 ) ,5343-51

McCormack, F X; King, T E; Bucher, B L; Nielsen, L; Mason, R J; McCormac, F X (1995. ) Surfactant protein A predicts survival in idiopathic pulmonary fibrosis. American journal of respiratory and critical care medicine, , 152 (2 ) ,751-9

McCormack, F X; Kuroki, Y; Stewart, J J; Mason, R J; Voelker, D R (1994. ) Surfactant protein A amino acids Glu195 and Arg197 are essential for receptor binding, phospholipid aggregation, regulation of secretion, and the facilitated uptake of phospholipid by type II cells. The Journal of biological chemistry, , 269 (47 ) ,29801-7

Ogasawara, Y; McCormack, F X; Mason, R J; Voelker, D R (1994. ) Chimeras of surfactant proteins A and D identify the carbohydrate recognition domains as essential for phospholipid interaction. The Journal of biological chemistry, , 269 (47 ) ,29785-92

Kuroki, Y; McCormack, F X; Ogasawara, Y; Mason, R J; Voelker, D R (1994. ) Epitope mapping for monoclonal antibodies identifies functional domains of pulmonary surfactant protein A that interact with lipids. The Journal of biological chemistry, , 269 (47 ) ,29793-800

McCormack, F X; Calvert, H M; Watson, P A; Smith, D L; Mason, R J; Voelker, D R (1994. ) The structure and function of surfactant protein A. Hydroxyproline- and carbohydrate-deficient mutant proteins. The Journal of biological chemistry, , 269 (8 ) ,5833-41

de Carvalho, M S; McCormack, F X; Leslie, C C (1993. ) The 85-kDa, arachidonic acid-specific phospholipase A2 is expressed as an activated phosphoprotein in Sf9 cells. Archives of biochemistry and biophysics, , 306 (2 ) ,534-40

Kalina, M; McCormack, F X; Crowley, H; Voelker, D R; Mason, R J (1993. ) Internalization of surfactant protein A (SP-A) into lamellar bodies of rat alveolar type II cells in vitro. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, , 41 (1 ) ,57-70

Zimmerman, P E; Voelker, D R; McCormack, F X; Paulsrud, J R; Martin, W J (1992. ) 120-kD surface glycoprotein of Pneumocystis carinii is a ligand for surfactant protein A.The Journal of clinical investigation, , 89 (1 ) ,143-9 More Information

McCormack, F X; King, T E; Voelker, D R; Robinson, P C; Mason, R J (1991. ) Idiopathic pulmonary fibrosis. Abnormalities in the bronchoalveolar lavage content of surfactant protein A. The American review of respiratory disease, , 144 (1 ) ,160-6

Fisher, J H; McCormack, F; Park, S S; Stelzner, T; Shannon, J M; Hofmann, T (1991. ) In vivo regulation of surfactant proteins by glucocorticoids.American journal of respiratory cell and molecular biology, , 5 (1 ) ,63-70 More Information

McCormack, F X; Fisher, J H; Suwabe, A; Smith, D L; Shannon, J M; Voelker, D R (1990. ) Expression and characterization of rat surfactant protein A synthesized in Chinese hamster ovary cells. Biochimica et biophysica acta, , 1087 (2 ) ,190-8

Mackenzie, C F; Shin, B; Krishnaprasad, D; McCormack, F; Illingworth, W (1985. ) Assessment of cardiac and respiratory function during surgery on patients with acute quadriplegia.Journal of neurosurgery, , 62 (6 ) ,843-9 More Information

Sykes, J A; McCormack, F X; O'Brien, T J (1978. ) A preliminary study of the superoxide dismutase content of some human tumors. Cancer research, , 38 (9 ) ,2759-62

McCormack, Francis X The way forward in lymphangioleiomyomatosis: a trial for every patient, every patient in a trial. Jornal brasileiro de pneumologia : publicaça?o oficial da Sociedade Brasileira de Pneumologia e Tisilogia, , 37 (4 ) ,422-3

McCormack, F X Functional mapping of surfactant protein A. Pediatric pathology & molecular medicine, , 20 (4 ) ,293-318

Kotloff, Robert M; McCormack, Francis X (2016. ) Rare Lung Diseases: Occasionally the "Horse" Has Stripes.Clinics in chest medicine, , 37 (3 ) ,xv-xvi More Information

Saito, Atsushi; McCormack, Francis X (2016. ) Pulmonary Alveolar Microlithiasis.Clinics in chest medicine, , 37 (3 ) ,441-8 More Information

Itkin, Maxim; McCormack, Francis X (2016. ) Nonmalignant Adult Thoracic Lymphatic Disorders.Clinics in chest medicine, , 37 (3 ) ,409-20 More Information

Takada, Toshinori; Mikami, Ayako; Kitamura, Nobutaka; Seyama, Kuniaki; Inoue, Yoshikazu; Nagai, Katsura; Suzuki, Masaru; Moriyama, Hiroshi; Akasaka, Keiichi; Tazawa, Ryushi; Hirai, Toyohiro; Mishima, Michiaki; Hayashida, Mie; Hirose, Masaki; Sugimoto, Chikatoshi; Arai, Toru; Hattori, Noboru; Watanabe, Kentaro; Tamada, Tsutomu; Yoshizawa, Hirohisa; Akazawa, Kohei; Tanaka, Takahiro; Yagi, Keita; Young, Lisa R; McCormack, Francis X; Nakata, Koh (2016. ) Efficacy and Safety of Long-term Sirolimus Therapy for Asian Patients with Lymphangioleiomyomatosis.Annals of the American Thoracic Society, , More Information

Goh, Boon Chong; Wu, Huixing; Rynkiewicz, Michael J; Schulten, Klaus; Seaton, Barbara A; McCormack, Francis X (2016. ) Elucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations.Biochemistry, , 55 (26 ) ,3692-701 More Information

Gardner, Jason C; Wu, Huixing; Noel, John G; Ramser, Benjamin J; Pitstick, Lori; Saito, Atsushi; Nikolaidis, Nikolaos M; McCormack, Francis X (2016. ) Keratinocyte growth factor supports pulmonary innate immune defense through maintenance of alveolar antimicrobial protein levels and macrophage function.American journal of physiology. Lung cellular and molecular physiology, , 310 (9 ) ,L868-79 More Information

Argula, Rahul G; Kokosi, Maria; Lo, Pechin; Kim, Hyun J; Ravenel, James G; Meyer, Cristopher; Goldin, Jonathan; Lee, Hye-Seung; Strange, Charlie; McCormack, Francis X (2016. ) A Novel Quantitative Computed Tomographic Analysis Suggests How Sirolimus Stabilizes Progressive Air Trapping in Lymphangioleiomyomatosis.Annals of the American Thoracic Society, , 13 (3 ) ,342-9 More Information

Gupta, Nishant; Wikenheiser-Brokamp, Kathryn A; Fischer, Aryeh; McCormack, Francis X (2016. ) Diffuse Cystic Lung Disease as the Presenting Manifestation of Sjögren Syndrome.Annals of the American Thoracic Society, , 13 (3 ) ,371-5 More Information

Soleimani, Manoocher; Barone, Sharon; Xu, Jie; Alshahrani, Saeed; Brooks, Marybeth; McCormack, Francis X; Smith, Roger D; Zahedi, Kamyar (2016. ) Prostaglandin-E2 Mediated Increase in Calcium and Phosphate Excretion in a Mouse Model of Distal Nephron Salt Wasting.PloS one, , 11 (7 ) ,e0159804 More Information

Saito, Atsushi; Nikolaidis, Nikolaos M; Amlal, Hassane; Uehara, Yasuaki; Gardner, Jason C; LaSance, Kathleen; Pitstick, Lori B; Bridges, James P; Wikenheiser-Brokamp, Kathryn A; McGraw, Dennis W; Woods, Jason C; Sabbagh, Yves; Schiavi, Susan C; Altini?ik, Göksel; Jakopovi?, Marko; Inoue, Yoshikazu; McCormack, Francis X (2015. ) Modeling pulmonary alveolar microlithiasis by epithelial deletion of the Npt2b sodium phosphate cotransporter reveals putative biomarkers and strategies for treatment.Science translational medicine, , 7 (313 ) ,313ra181 More Information

Gupta, Nishant; Meraj, Riffat; Tanase, Daniel; James, Laura E; Seyama, Kuniaki; Lynch, David A; Akira, Masanori; Meyer, Cristopher A; Ruoss, Stephen J; Burger, Charles D; Young, Lisa R; Almoosa, Khalid F; Veeraraghavan, Srihari; Barker, Alan F; Lee, Augustine S; Dilling, Daniel F; Inoue, Yoshikazu; Cudzilo, Corey J; Zafar, Muhammad A; McCormack, Francis X (2015. ) Accuracy of chest high-resolution computed tomography in diagnosing diffuse cystic lung diseases.The European respiratory journal, , 46 (4 ) ,1196-9 More Information

Goldberg, Hilary J; Harari, Sergio; Cottin, Vincent; Rosas, Ivan O; Peters, Elizabeth; Biswal, Shibadas; Cheng, Yi; Khindri, Sanjeev; Kovarik, John M; Ma, Shenglin; McCormack, Francis X; Henske, Elizabeth Petri (2015. ) Everolimus for the treatment of lymphangioleiomyomatosis: a phase II study.The European respiratory journal, , 46 (3 ) ,783-94 More Information

Gupta, Nishant; Han, MeiLan K; McCormack, Francis X (2015. ) Regional Sparing in an Oligemic Lung Segment Supports Hematogenous Spread as a Pathogenic Mechanism in Lymphangioleiomyomatosis.Annals of the American Thoracic Society, , 12 (8 ) ,1247-8 More Information

Gupta, Nishant; Vassallo, Robert; Wikenheiser-Brokamp, Kathryn A; McCormack, Francis X (2015. ) Diffuse Cystic Lung Disease. Part II.American journal of respiratory and critical care medicine, , 192 (1 ) ,17-29 More Information

Gupta, Nishant; Vassallo, Robert; Wikenheiser-Brokamp, Kathryn A; McCormack, Francis X (2015. ) Diffuse Cystic Lung Disease. Part I.American journal of respiratory and critical care medicine, , 191 (12 ) ,1354-66 More Information

Quintanilla, Hector D; Liu, Yuying; Fatheree, Nicole Y; Atkins, Constance L; Hashmi, Syed S; Floros, Joanna; McCormack, Francis X; Rhoads, Jon Marc; Alcorn, Joseph L (2015. ) Oral administration of surfactant protein-a reduces pathology in an experimental model of necrotizing enterocolitis.Journal of pediatric gastroenterology and nutrition, , 60 (5 ) ,613-20 More Information

Pasula, Rajamouli; Azad, Abul K; Gardner, Jason C; Schlesinger, Larry S; McCormack, Francis X (2015. ) Keratinocyte growth factor administration attenuates murine pulmonary mycobacterium tuberculosis infection through granulocyte-macrophage colony-stimulating factor (GM-CSF)-dependent macrophage activation and phagolysosome fusion.The Journal of biological chemistry, , 290 (11 ) ,7151-9 More Information

Gupta, Rajeev; McCormack, Francis X (2015. ) Response. Lymphology, , 48 (1 ) ,52

Mulhall, Aaron M; McCormack, Francis X (2015. ) A 25-year-old man with fatigue, dyspnea, and pulmonary cysts.Annals of the American Thoracic Society, , 12 (1 ) ,120-3 More Information

Yang, Linlin; Carrillo, Marykate; Wu, Yuchieh M; DiAngelo, Susan L; Silveyra, Patricia; Umstead, Todd M; Halstead, E Scott; Davies, Michael L; Hu, Sanmei; Floros, Joanna; McCormack, Francis X; Christensen, Neil D; Chroneos, Zissis C (2015. ) SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation.PloS one, , 10 (5 ) ,e0126576 More Information

McCormack, Francis X (2014. ) Chronic sirolimus therapy for lymphangioleiomyomatosis.American journal of respiratory and critical care medicine, , 190 (12 ) ,1332-3 More Information

Gupta, R; Kitaichi, M; Inoue, Y; Kotloff, R; McCormack, F X (2014. ) Lymphatic manifestations of lymphangioleiomyomatosis. Lymphology, , 47 (3 ) ,106-17

mccormack, f.x.

Krymskaya, Vera P; McCormack, Francis X (2017. ) Lymphangioleiomyomatosis: A Monogenic Model of Malignancy.Annual review of medicine, , 68 ,69-83 More Information

Gupta, Nishant; Langenderfer, Dale; McCormack, Francis X; Schauer, Daniel P; Eckman, Mark H (2017. ) Chest Computed Tomographic Image Screening for Cystic Lung Diseases in Patients with Spontaneous Pneumothorax Is Cost Effective.Annals of the American Thoracic Society, , 14 (1 ) ,17-25 More Information

Osterburg, Andrew R; Nelson, Rebecca L; Yaniv, Benyamin Z; Foot, Rachel; Donica, Walter R F; Nashu, Madison A; Liu, Huan; Wikenheiser-Brokamp, Kathryn A; Moss, Joel; Gupta, Nishant; McCormack, Francis X; Borchers, Michael T (2016. ) NK cell activating receptor ligand expression in lymphangioleiomyomatosis is associated with lung function decline.JCI insight, , 1 (16 ) ,e87270 More Information

Itkin, Maxim G; McCormack, Francis X; Dori, Yoav (2016. ) Diagnosis and Treatment of Lymphatic Plastic Bronchitis in Adults Using Advanced Lymphatic Imaging and Percutaneous Embolization.Annals of the American Thoracic Society, , 13 (10 ) ,1689-1696 More Information

McCormack, Francis X; Gupta, Nishant; Finlay, Geraldine R; Young, Lisa R; Taveira-DaSilva, Angelo M; Glasgow, Connie G; Steagall, Wendy K; Johnson, Simon R; Sahn, Steven A; Ryu, Jay H; Strange, Charlie; Seyama, Kuniaki; Sullivan, Eugene J; Kotloff, Robert M; Downey, Gregory P; Chapman, Jeffrey T; Han, MeiLan K; D'Armiento, Jeanine M; Inoue, Yoshikazu; Henske, Elizabeth P; Bissler, John J; Colby, Thomas V; Kinder, Brent W; Wikenheiser-Brokamp, Kathryn A; Brown, Kevin K; Cordier, Jean F; Meyer, Cristopher; Cottin, Vincent; Brozek, Jan L; Smith, Karen; Wilson, Kevin C; Moss, Joel (2016. ) Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guidelines: Lymphangioleiomyomatosis Diagnosis and Management.American journal of respiratory and critical care medicine, , 194 (6 ) ,748-61 More Information

Han, MeiLan K; Tyburczy, Magdalena E; Darling, Thomas N; Kazerooni, Ella A; Myers, Jeffrey L; McCormack, Francis X; Moss, Joel; Kwiatkowski, David J (2017. ) Apparent Sporadic Lymphangioleiomyomatosis (LAM) in a Man Due to Extreme Mosaicism for a TSC2 Mutation.Annals of the American Thoracic Society, , More Information

Liu, Huan; Jakubzick, Claudia; Osterburg, Andrew R; Nelson, Rebecca L; Gupta, Nishant; McCormack, Francis X; Borchers, Michael T (2017. ) Dendritic Cell Trafficking and Function in Rare Lung Diseases.American journal of respiratory cell and molecular biology, , More Information

Lu, Calvin; Lee, Hye-Seung; Pappas, George P; Dilling, Daniel F; Burger, Charles D; Shifren, Adrian; Veeraraghavan, Srihari; Chapman, Jeffrey T; Parambil, Joseph; Ruoss, Stephen J; Young, Lisa R; Hammes, Stephen R; Kopras, Elizabeth J; Roads, Tammy; Krischer, Jeffrey P; McCormack, Francis X (2017. ) A Phase II Clinical Trial of an Aromatase Inhibitor for Postmenopausal Women with Lymphangioleiomyomatosis.Annals of the American Thoracic Society, , 14 (6 ) ,919-928 More Information

Gupta, Nishant; Kopras, Elizabeth J; Henske, Elizabeth P; James, Laura E; El-Chemaly, Souheil; Veeraraghavan, Srihari; Drake, Matthew G; McCormack, Francis X (2017. ) Spontaneous Pneumothoraces in Patients with Birt-Hogg-Dubé Syndrome.Annals of the American Thoracic Society, , 14 (5 ) ,706-713 More Information

McCormack, Francis X; Gupta, Nishant; Finlay, Geraldine; Young, Lisa R; Johnson, Simon; Cottin, Vincent; Wilson, Kevin; Moss, Joel (2017. ) Reply to Official ATS/JRS Clinical Practice Guidelines: Lymphangioleiomyomatosis Diagnosis and Management.American journal of respiratory and critical care medicine, , More Information

Sontake, Vishwaraj; Wang, Yunguan; Kasam, Rajesh K; Sinner, Debora; Reddy, Geereddy B; Naren, Anjaparavanda P; McCormack, Francis X; White, Eric S; Jegga, Anil G; Madala, Satish K (2017. ) Hsp90 regulation of fibroblast activation in pulmonary fibrosis.JCI insight, , 2 (4 ) ,e91454 More Information

Lee, Lynn H; Gasilina, Anjelika; Roychoudhury, Jayeeta; Clark, Jason; McCormack, Francis X; Pressey, Joseph; Grimley, Michael S; Lorsbach, Robert; Ali, Siraj; Bailey, Mark; Stephens, Philip; Ross, Jeffrey S; Miller, Vincent A; Nassar, Nicolas N; Kumar, Ashish R (2017. ) Real-time genomic profiling of histiocytoses identifies early-kinase domain BRAF alterations while improving treatment outcomes.JCI insight, , 2 (3 ) ,e89473 More Information

Rynkiewicz, Michael J; Wu, Huixing; Cafarella, Tanya R; Nikolaidis, Nikolaos M; Head, James F; Seaton, Barbara A; McCormack, Francis X (2017. ) Differential Ligand Binding Specificities of the Pulmonary Collectins Are Determined by the Conformational Freedom of a Surface Loop.Biochemistry, , 56 (31 ) ,4095-4105 More Information

Nikolaidis, Nikolaos M; Noel, John G; Pitstick, Lori B; Gardner, Jason C; Uehara, Yasuaki; Wu, Huixing; Saito, Atsushi; Lewnard, Kara E; Liu, Huan; White, Mitchell R; Hartshorn, Kevan L; McCormack, Francis X (2017. ) Mitogenic stimulation accelerates influenza-induced mortality by increasing susceptibility of alveolar type II cells to infection.Proceedings of the National Academy of Sciences of the United States of America, , 114 (32 ) ,E6613-E6622 More Information

Kristof, Arnold S; Petrof, Basil J; Hamid, Qutayba; Kolb, Martin; Landry, Jennifer S; MacKenzie, Alex; McCormack, Francis X; Murawski, Inga J; Moss, Joel; Rauch, Frank; Rosas, Ivan O; Shapiro, Adam J; Smith, Benjamin M; Thomas, David Y; Trapnell, Bruce C; Young, Lisa R; Zariwala, Maimoona A (2017. ) An Official American Thoracic Society Workshop Report: Translational Research in Rare Respiratory Diseases.Annals of the American Thoracic Society, , 14 (8 ) ,1239-1247 More Information

Feemster, Laura C; Lyons, Patrick G; Chatterjee, Rohini S; Kidambi, Pranav; McCormack, Francis X; Moss, Joel; Wilson, Kevin C; Thomson, Carey C (2017. ) Summary for Clinicians: Lymphangioleiomyomatosis Diagnosis and Management Clinical Practice Guideline.Annals of the American Thoracic Society, , 14 (7 ) ,1073-1075 More Information

Noel, John G; Ramser, Benjamin J; Cancelas, Jose A; McCormack, Francis X; Gardner, Jason C (2017. ) Thermal injury of the skin induces G-CSF-dependent attenuation of EPO-mediated STAT signaling and erythroid differentiation arrest in mice.Experimental hematology, , More Information

Gupta, Nishant; Lee, Hye-Seung; Young, Lisa R; Strange, Charlie; Moss, Joel; Singer, Lianne G; Nakata, Koh; Barker, Alan F; Chapman, Jeffrey T; Brantly, Mark L; Stocks, James M; Brown, Kevin K; Lynch, Joseph P; Goldberg, Hilary J; Downey, Gregory P; Taveira-DaSilva, Angelo M; Krischer, Jeffrey P; Setchell, Kenneth; Trapnell, Bruce C; Inoue, Yoshikazu; McCormack, Francis X (2019. ) Analysis of the MILES cohort reveals determinants of disease progression and treatment response in lymphangioleiomyomatosis.The European respiratory journal, , 53 (4 ) , More Information

Zak, Sara; Mokhallati, Nadine; Su, Weiji; McCormack, Francis X; Franz, David N; Mays, Maxwell; Krueger, Darcy A; Szczesniak, Rhonda D; Gupta, Nishant (2019. ) Lymphangioleiomyomatosis Mortality in Patients with Tuberous Sclerosis Complex.Annals of the American Thoracic Society, , 16 (4 ) ,509-512 More Information

McCarthy, Cormac; Bartholmai, Brian J; Woods, Jason C; McCormack, Francis X; Trapnell, Bruce C (2019. ) Automated Parenchymal Pattern Analysis of Treatment Responses in Pulmonary Alveolar Proteinosis.American journal of respiratory and critical care medicine, , More Information

Hirose, Masaki; Matsumuro, Akiko; Arai, Toru; Sugimoto, Chikatoshi; Akira, Masanori; Kitaichi, Masanori; Young, Lisa R; McCormack, Francis X; Inoue, Yoshikazu (2019. ) Serum vascular endothelial growth factor-D as a diagnostic and therapeutic biomarker for lymphangioleiomyomatosis.PloS one, , 14 (2 ) ,e0212776 More Information

Gupta, Nishant; Lee, Hye-Seung; Ryu, Jay H; Taveira-DaSilva, Angelo M; Beck, Gerald J; Lee, Jar-Chi; McCarthy, Kevin; Finlay, Geraldine A; Brown, Kevin K; Ruoss, Stephen J; Avila, Nilo A; Moss, Joel; McCormack, Francis X (2019. ) The NHLBI LAM Registry: Prognostic Physiologic and Radiologic Biomarkers Emerge From a 15-Year Prospective Longitudinal Analysis.Chest, , 155 (2 ) ,288-296 More Information

Miller, Suzanne; Coveney, Clare; Johnson, Janice; Farmaki, Aliki-Eleni; Gupta, Nishant; Tobin, Martin D; Wain, Louise V; McCormack, Francis X; Boocock, David J; Johnson, Simon R (2018. ) The vitamin D binding protein axis modifies disease severity in lymphangioleiomyomatosis.The European respiratory journal, , 52 (5 ) , More Information

Liu, Huan; Osterburg, Andrew R; Flury, Jennifer; Huang, Shuo; McCormack, Francis X; Cormier, Stephania A; Borchers, Michael T (2018. ) NKG2D Regulation of Lung Pathology and Dendritic Cell Function Following Respiratory Syncytial Virus Infection.The Journal of infectious diseases, , 218 (11 ) ,1822-1832 More Information

Gupta, Nishant; Colby, Thomas V; Meyer, Cristopher A; McCormack, Francis X; Wikenheiser-Brokamp, Kathryn A (2018. ) Smoking-Related Diffuse Cystic Lung Disease.Chest, , 154 (2 ) ,e31-e35 More Information

Gupta, Nishant; Johnson, Simon R; Moss, Joel; McCormack, Francis X (2018. ) Reply to Yanagisawa: Treatment of Pulmonary Lymphangioleiomyomatosis during Pregnancy.American journal of respiratory and critical care medicine, , 197 (11 ) ,1507-1508 More Information

Gupta, Nishant; Finlay, Geraldine A; Kotloff, Robert M; Strange, Charlie; Wilson, Kevin C; Young, Lisa R; Taveira-DaSilva, Angelo M; Johnson, Simon R; Cottin, Vincent; Sahn, Steven A; Ryu, Jay H; Seyama, Kuniaki; Inoue, Yoshikazu; Downey, Gregory P; Han, MeiLan K; Colby, Thomas V; Wikenheiser-Brokamp, Kathryn A; Meyer, Cristopher A; Smith, Karen; Moss, Joel; McCormack, Francis X (2017. ) Lymphangioleiomyomatosis Diagnosis and Management: High-Resolution Chest Computed Tomography, Transbronchial Lung Biopsy, and Pleural Disease Management. An Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guideline.American journal of respiratory and critical care medicine, , 196 (10 ) ,1337-1348 More Information

Wang, Yunguan; Yella, Jaswanth; Chen, Jing; McCormack, Francis X; Madala, Satish K; Jegga, Anil G (2017. ) Unsupervised gene expression analyses identify IPF-severity correlated signatures, associated genes and biomarkers.BMC pulmonary medicine, , 17 (1 ) ,133 More Information

McCarthy, Cormac; Lara Gallego, Beatriz; Trapnell, Bruce C; McCormack, Francis X (2017. ) Epidemiology of Rare Lung Diseases: The Challenges and Opportunities to Improve Research and Knowledge.Advances in experimental medicine and biology, , 1031 ,419-442 More Information

Guo, Minzhe; Yu, Jane J; Perl, Anne Karina; Wikenheiser-Brokamp, Kathryn A; Riccetti, Matt; Zhang, Erik Y; Sudha, Parvathi; Adam, Mike; Potter, Andrew; Kopras, Elizabeth J; Giannikou, Krinio; Potter, S Steven; Sherman, Sue; Hammes, Stephen R; Kwiatkowski, David J; Whitsett, Jeffrey A; McCormack, Francis X; Xu, Yan (2020. ) Single Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell.American journal of respiratory and critical care medicine, , More Information

Poovelikunnel, Toney T; Duffy, Fionnuala; Puthussery, Thressia; Gangadharan, Shaini; McCormack, Fiona; Carpenter, Helen; Kizhakedath, Mary; Hawkshaw, Susan (2020. ) Clinically indicated replacement of peripheral vascular catheters: is it safe for patients?.British journal of nursing (Mark Allen Publishing), , 29 (8 ) ,S4-S10 More Information

Shaw, Brian M; Shaw, Steven D; McCormack, Francis X (2020. ) Pulmonary Alveolar Microlithiasis.Seminars in respiratory and critical care medicine, , 41 (2 ) ,280-287 More Information

Krymskaya, Vera P; Courtwright, Andrew M; Fleck, Victoria; Dorgan, Daniel; Kotloff, Robert; McCormack, Francis X; Kreider, Maryl (2020. ) A phase II clinical trial of the Safety Of Simvastatin (SOS) in patients with pulmonary lymphangioleiomyomatosis and with tuberous sclerosis complex.Respiratory medicine, , 163 ,105898 More Information

Jönsson, Åsa Lina M; Bendstrup, Elisabeth; Mogensen, Susie; Kopras, Elizabeth J; McCormack, Francis X; Campo, Ilaria; Mariani, Francesca; Escribano-Montaner, Amparo; Holm, Are M; Martinez-Colls, Maria Del Mar; Pintos-Morell, Guillem; Taillé, Camille; Crestani, Bruno; Hilberg, Ole; Hvarregaard Christensen, Jane; Simonsen, Ulf (2020. ) Eight novel variants in the SLC34A2 gene in pulmonary alveolar microlithiasis.The European respiratory journal, , 55 (2 ) , More Information

Liu, Huan; Osterburg, Andrew R; Flury, Jennifer; Swank, Zulma; McGraw, Dennis W; Gupta, Nishant; Wikenheiser-Brokamp, Kathryn A; Kumar, Ashish; Tazi, Abdellatif; Inoue, Yoshikazu; Hirose, Masaki; McCormack, Francis X; Borchers, Michael T (2020. ) MAPK mutations and cigarette smoke promote the pathogenesis of pulmonary Langerhans cell histiocytosis.JCI insight, , 5 (4 ) , More Information

Nalian, Armen; Umstead, Todd M; Yang, Ching-Hui; Silveyra, Patricia; Thomas, Neal J; Floros, Joanna; McCormack, Francis X; Chroneos, Zissis C (2019. ) Structural and Functional Determinants of Rodent and Human Surfactant Protein A: A Synthesis of Binding and Computational Data.Frontiers in immunology, , 10 ,2613 More Information

Walkup, Laura L; Roach, David J; Hall, Chase S; Gupta, Nishant; Thomen, Robert P; Cleveland, Zackary I; McCormack, Francis X; Woods, Jason C (2019. ) Cyst Ventilation Heterogeneity and Alveolar Airspace Dilation as Early Disease Markers in Lymphangioleiomyomatosis.Annals of the American Thoracic Society, , 16 (8 ) ,1008-1016 More Information

McCarthy, Cormac; McCormack, Francis X (2019. ) Recurrent Sinusitis, Lower Limb Edema, and Nail Changes.Annals of the American Thoracic Society, , 16 (6 ) ,752-755 More Information

Gupta, R; Kitaichi, M; Inoue, Y; Kotloff, R; McCormack, F X (2014. ) Lymphatic manifestations of lymphangioleiomyomatosis. Lymphology, , 47 (3 ) ,106-17

Singla A.;Gupta N.;Apewokin S.;McCormack F. (11-02-2017. ) Sirolimus for the treatment of lymphangioleiomyomatosis.Expert Opinion on Orphan Drugs, , 5 (11 ) ,907-921 More Information

Kotloff R.;McCormack F. (09-01-2016. ) Rare Lung Diseases: Occasionally the “Horse” Has Stripes.Clinics in Chest Medicine, , 37 (3 ) ,xv-xvi More Information

McCormack F. (04-19-2016. ) Lymphangioleiomyomatosis .Interstitial Pulmonary and Bronchiolar Disorders, , 747-768

Struik M.H.L.;Van Moorsel C.H.M.;Van Beek F.T.;Veltkamp M.;Mccormack F.X.;Grutters J.C. (04-01-2015. ) The importance of biobank and nationwide registry for lymphangioleiomyomatosis in a small sized coun.Expert Opinion on Orphan Drugs, , 3 (4 ) ,393-401 More Information

Swigris J.;Lee H.;Cohen M.;Inoue Y.;Moss J.;Singer L.;Young L.;McCormack F. (01-01-2013. ) St. George's respiratory questionnaire has longitudinal construct validity in lymphangioleiomyomatos.Chest, , 143 (6 ) ,1671-1678 More Information

Cudzilo C.J.;Szczesniak R.D.;Brody A.S.;Rattan M.S.;Krueger D.A.;Bissler J.J.;Franz D.N.;McCormack F.X.;Young L.R. (01-01-2013. ) Lymphangioleiomyomatosis screening in women with tuberous sclerosis.Chest, , 144 (2 ) ,578-585 More Information

McCormack F.;Lee H.;Trapnell B. (07-21-2011. ) The authors reply .New England Journal of Medicine, , 365 (3 ) ,272

McCormack F.X.;Inoue Y.;Moss J.;Singer L.G.;Strange C.;Nakata K.;Barker A.F.;Chapman J.T.;Brantly M.L.;Stocks J.M.;Brown K.K.;Lynch J.P.;Goldberg H.J.;Young L.R.;Kinder B.W.;Downey G.P.;Sullivan E.J.;Colby T.V.;McKay R.T.;Cohen M.M.;Korbee L.;Taveira-DaSilva A.M.;Lee H.S.;Krischer J.P.;Trapnell B.C. (04-28-2011. ) Efficacy and safety of sirolimus in lymphangioleiomyomatosis.New England Journal of Medicine, , 364 (17 ) ,1595-1606 More Information

Hagaman J.;Panos R.;McCormack F.;Thakar C.;Wikenheiser-Brokamp K.;Shipley R.;Kinder B. (02-01-2011. ) Vitamin D deficiency and reduced lung function in connective tissue-associated interstitial lung dis.Chest, , 139 (2 ) ,353-360 More Information

McCormack F.;Henske E. (06-09-2010. ) Lymphangioleiomyomatosis and Pulmonary Disease in TSC.Tuberous Sclerosis Complex: Genes, Clinical Features and Therapeutics, , 345-368 More Information

Hagaman J.T.;Ferguson B.;Meyer C.;Wang J.;McCormack F.X.;Nath A. (04-01-2010. ) Endobronchial carcinoid tumor in an HIV-infected patient.Journal of Bronchology and Interventional Pulmonology, , 17 (2 ) ,174-176 More Information

Johnson S.R.;Cordier J.F.;Lazor R.;Cottin V.;Costabel U.;Harari S.;Reynaud-Gaubert M.;Boehler A.;Brauner M.;Popper H.;Bonetti F.;Kingswood C.;Albera C.;Bissler J.;Bouros D.;Corris P.;Donnelly S.;Durand C.;Egan J.;Grutters J.C.;Hodgson U.;Hollis G.;Korzeniewska-Kosela M.;Kus J.;Lacronique J.;Lammers J.W.;McCormack F.;Mendes A.C.;Moss J.;Naalsund A.;Pohl W.;Radzikowska E.;Robalo-Cordeiro C.;Rouvière O.;Ryu J.;Schiavina M.;Tattersfield A.E.;Travis W.;Tukiainen P.;Urban T.;Valeyre D.;Verleden G.M. (01-01-2010. ) European Respiratory Society guidelines for the diagnosis and management of lymphangioleiomyomatosis.European Respiratory Journal, , 35 (1 ) ,14-26 More Information

Bissler J.;Young L.;McCormack F. (05-01-2008. ) Dr. Bissler and colleagues reply .New England Journal of Medicine, , 358 (18 ) ,1964

McCormack F. (01-01-2008. ) Response.Chest, , 134 (1 ) ,218 More Information

Kingma P.;Zhang L.;Ikegami M.;Hartshorn K.;McCormack F.;Whitsett J. (12-15-2006. ) Erratum: Correction of pulmonary abnormalities in Sftpd-/- mice requires the .Journal of Biological Chemistry, , 281 (50 ) ,38968

McCormack F. (03-31-2006. ) Author's Reply to "Reader's response to 'Lymphangioleiomyomatosis'" .MedGenMed Medscape General Medicine, , 8 (1 ) ,

Zhang S.;Chen Y.;Potvin E.;Sanschagrin F.;Levesque R.;McCormack F.;Lau G. (12-01-2005. ) Comparative signature-tagged mutagenesis identifies Pseudomonas factors conferring resistance to the.PLoS Pathogens, , 1 (3 ) ,0259-0268 More Information

Almoosa K.F.;Khoury S.F.;McCormack F.X. (01-01-2003. ) Acute myocardial infarction complicating sudden interruption of chronic prostacyclin therapy for pul.Clinical Pulmonary Medicine, , 10 (4 ) ,231-234 More Information

Bridges J.P.;Davis H.W.;Damodarasamy M.;Kuroki Y.;Howles G.;Hui D.Y.;Francis-X. McCormack (12-13-2002. ) Erratum: Pulmonary surfactant proteins A and D are potent endogenous inhihitors of lipid peroxidatio .Journal of Biological Chemistry, , 277 (50 ) ,49090

Malloy J.;Veldhuizen R.;McCormack F.;Korfhagen T.;Whitsett J.;Lewis J. (01-01-2002. ) Pulmonary surfactant and inflammation in septic adult mice: Role of surfactant protein A.Journal of Applied Physiology, , 92 (2 ) ,809-816 More Information

Blau H.;Riklis S.;Van Iwaarden J.;McCormack F.;Kalina M. (12-01-1997. ) Nitric oxide production by rat alveolar macrophages can be modulated in vitro by surfactant protein .Pneumologie, , 51 (11 ) ,1080

McCormack F.X. (01-01-1995. ) Molecular biology of the surfactant apoproteins.Seminars in Respiratory and Critical Care Medicine, , 16 (1 ) ,29-38 More Information

McCormack F.;King T.;Bucher B.;Nielsen L.;Mason R. (01-01-1995. ) Erratum: Surfactant protein A predicts survival in idiopathic pulmonary fibrosis (American Journal o .American Journal of Respiratory and Critical Care Medicine, , 152 (4 I ) ,1425

De Carvalho M.;McCormack F.;Leslie C. (01-01-1993. ) The 85-kDa, Arachidonic Acid-Specific Phospholipase A2 Is Expressed as an Act.Archives of Biochemistry and Biophysics, , 306 (2 ) ,534-540 More Information

Dellinger, Michael T; McCormack, Francis X (2020. ) The emergence of targetable MEKanisms in sporadic lymphatic disorders.EMBO molecular medicine, , e12822 More Information

Gupta, Nishant; Hagner, Miles; Wu, Huixing; Young, Lisa R; Palipana, Anushka; Szczesniak, Rhonda D; McCormack, Francis X (2020. ) Serum Vascular Endothelial Growth Factor-C as a Marker of Therapeutic Response to Sirolimus in Lymphangioleiomyomatosis.Annals of the American Thoracic Society, , More Information

Gupta, Nishant; Bleesing, Jack H; McCormack, Francis X (2020. ) Successful Response to Treatment with Sirolimus in Pulmonary Sarcoidosis.American journal of respiratory and critical care medicine, , More Information

McCarthy, Cormac; Gupta, Nishant; Johnson, Simon R; Yu, Jane J; McCormack, Francis X (2021. ) Lymphangioleiomyomatosis: pathogenesis, clinical features, diagnosis, and management.The Lancet. Respiratory medicine, , More Information

Northrup, Hope; Aronow, Mary E; Bebin, E Martina; Bissler, John; Darling, Thomas N; de Vries, Petrus J; Frost, Michael D; Fuchs, Zoë; Gosnell, Elizabeth S; Gupta, Nishant; Jansen, Anna C; Jó?wiak, Sergiusz; Kingswood, J Chris; Knilans, Timothy K; McCormack, Francis X; Pounders, Ashley; Roberds, Steven L; Rodriguez-Buritica, David F; Roth, Jonathan; Sampson, Julian R; Sparagana, Steven; Thiele, Elizabeth Anne; Weiner, Howard L; Wheless, James W; Towbin, Alexander J; Krueger, Darcy A (2021. ) Updated International Tuberous Sclerosis Complex Diagnostic Criteria and Surveillance and Management Recommendations.Pediatric neurology, , 123 ,50-66 More Information

Chernbumroong, Saisakul; Johnson, Janice; Gupta, Nishant; Miller, Suzanne; McCormack, Francis X; Garibaldi, Jonathan M; Johnson, Simon R (2021. ) Machine learning can predict disease manifestations and outcomes in lymphangioleiomyomatosis.The European respiratory journal, , 57 (6 ) , More Information

Foley, M; Duffy, F; Skally, M; McCormack, F; Finn, C; O'Connor, M; Cafferkey, J; Thomas, T; Burns, K; Fitzpatrick, F; O'Connell, K; Smyth, E G; Humphreys, H (2021. ) Evolving epidemiology of carbapenemase-producing Enterobacterales: one hospital's infection prevention and control response over nine years.The Journal of hospital infection, , 112 ,61-68 More Information

Tian, Xinlun; Glass, Jennifer E; Kwiatkowski, David J; Towbin, Alexander J; Li, Yinan; Sund, Kristen L; Krueger, Darcy A; Franz, David N; McCormack, Francis X; Gupta, Nishant (2021. ) Lymphangioleiomyomatosis Association with Underlying Genotype in Patients with Tuberous Sclerosis Complex.Annals of the American Thoracic Society, , 18 (5 ) ,815-819 More Information

Kosciuk, Patrick; Meyer, Cristopher; Wikenheiser-Brokamp, Kathryn A; McCormack, Francis X (2020. ) Pulmonary alveolar microlithiasis.European respiratory review : an official journal of the European Respiratory Society, , 29 (158 ) , More Information

Northrup H.; Aronow M.E.; Bebin E.M.; Bissler J.; Darling T.N.; de Vries P.J.; Frost M.D.; Fuchs Z.; Gosnell E.S.; Gosnell E.S.; Gupta N.; Jansen A.C.; Jó?wiak S.; Kingswood J.C.; Knilans T.K.; McCormack F.X.; Pounders A.; Roberds S.L.; Rodriguez-Buritica D.F.; Rodriguez-Buritica D.F.; Roth J.; Sampson J.R.; Sparagana S.; Thiele E.A.; Weiner H.L.; Wheless J.W.; Towbin A.J.; Krueger D.A.; Annear N.M.P.; Bartels U.; Berhouma M.; Bissler J.J.; Budde K.; Byars A.; Chugani H.; Cowen E.W.; Crino P.B.; Curatolo P.; de Vries P.; Dilling D.F.; Dunn D.W.; Ekong R.; Ess K.C.; Franz D.N.; Frost M.; Fuchs Z.D.B.; Guay-Woodford L.; Haddad L.; Halbert A.; Hebert A.A.; Henske E.P.; Holmes G.L.; Hook D.; Hulbert J.; Jansen A.; Johnson S.R.; King B.; Kingswood J.C.; Koenig M.K.; Korf B.; Kwiatkowski D.J.; Moss J.; Mowat D.; Mowrey K.; Nabbout R.; Nellist M.D.; O'Callaghan F.; Patel U.; Roach E.S.; Romp R.; Rozenberg M.; Ruoss S.J.; Sahin M.; Sampson J.; Samuels J.A.; Sauter M.; Smith C.A.; Soltani K.; Srivastava S.; Stuart C.; Teng J.M.C.; Thiele E.A.; Trout A.; van Eeghen A.; Vanclooster S.; Wang H.Z.; Wataya-Kaneda M.; Witman P.; Wright T.; Wu J.Y.; Young L. (10-01-2021. ) Updated International Tuberous Sclerosis Complex Diagnostic Criteria and Surveillance and Management.Pediatric Neurology, , 123 ,50-66 More Information

Published Books

McCormack, FX; Panos, RJ; Trapnell, BC (2010. ) Molecular Basis of Lung Disease; Insights from Rare Disorders .Humana Press (Editor)

Honors and Awards

2000 American Society for Clinical Investigation

2016 Association of American Physicians

2011 Alpha Omega Alpha

2012 American Thoracic Society Distinguished Achievement Award

Keywords

Surfactant Protein a,Surfactant Protein: Major Surface Glycoprotein,Alveolar Type II Cells

Patents and Inventions

20120010234 Use of VEGF-D in Diagnosis of LAM McCormack/Young, Awarded 2011 Co-Inventor

8,278,060 Use of VEGF-D in Diagnosis of LAM McCormack/Young, 2012 Co-Inventor

61/638,149 KGF For Mycobacterial Infection McCormack, Filed Inventor

Contact Information

Academic - Internal Medicine
Medical Sciences Building 6165
Cincinnati  Ohio, 45267
Phone: 513-558-4831
Fax: 513-558-4858
frank.mccormack@uc.edu