Daniel W. W Nebert , MD.

Daniel W Nebert, MD
Professor Emeritus

Bachelor's Degree: Wesleyan University Middletown CT, 1960 (Biochemistry)

Medical Degree: Univ Oregon Med School Portland, OR, 1964 (Medicine)

Master's Degree: Univ Oregon Med School Portland, OR, 1964 (Biophysics)

Inter ship and Residency : UCLA Health Sciences Center Los Angeles, Ca, 1966 (Pediatrics)

Postdoctoral Fellowship: National Institute of Health Bethesda, MD, 1968 (Cancer research)

Genes encoding drug-metabolizing enzymes; CYP1A1 gene; Ecogenetics; Standardized gene nomenclature; Gene superfamilies; Human Ah receptor gene; Environmental toxicology; Teratology; Cancer research.

Grant: #R01 ES010416 Investigators:Nebert, Daniel 09-30-2006 -07-31-2012 National Institute of Environmental Health Sciences Molecular Genetics of CD II Induced Disease Role:PI $1,671,274.00 Closed Level:Federal

Grant: #R01-DE016325 Investigators:Nebert, Daniel 04-01-2006 -03-31-2010 National Institute of Dental and Craniofacial Research Human HNSCC: CYP1B1/1A1/1A2 and AHR Gene Polymorphisms Role:PI $759,288.00 Closed Level:Federal

Grant: #SRS 003421 Investigators:Nebert, Daniel 07-01-2003 -12-31-2008 National Institute of Child Health and Human Development Pediatric Pharmacology Research Unit (PPRU) Role:PI $158,464.00 Closed Level:Federal

Grant: #R01 ES014403 Investigators:Nebert, Daniel 02-17-2006 -01-31-2011 National Institute of Environmental Health Sciences PAHs: Balance of Detoxification vs Metabolic Activation Role:PI $1,401,278.00 Closed Level:Federal

Grant: #5-R01-ES-08147-09-A0-S0-E0 Investigators:Nebert, Daniel 12-01-2000 -11-30-2006 National Institute of Environmental Health Sciences CYP1A1 Gene and Environmental Toxicity Role:PI $2,508,695.00 Closed Level:Federal

Grant: #5-R01-AG-09235-09-A0-S0-E0 Investigators:Nebert, Daniel 09-01-1995 -07-31-2000 National Institute on Aging Oxidative Stress, Cell Death and the [Ah] Gene Battery Role:PI $1,191,963.00 Closed Level:Federal

Grant: #5-R01-ES-08147-04-A0-S0-E0 Investigators:Nebert, Daniel 08-01-1996 -07-31-2000 National Institute of Environmental Health Sciences Role of the CYP1A1 Gene in Environmental Toxicity Role:PI $799,855.00 Closed Level:Federal

Grant: #5-R01-ES-06321-10-A0-S0-E0 Investigators:Nebert, Daniel 04-15-1998 -03-31-2004 National Institute of Environmental Health Sciences Genotoxicity in Cypia 2-Deficient Transgenic Mice Role:PI $1,192,301.00 Closed Level:Federal

Grant: #5-R01-ES-07058-03-A0-S0-E0 Investigators:Nebert, Daniel 03-01-1996 -02-29-2000 National Institute of Environmental Health Sciences Transgenic Zebrafish: Sentinel for Aquatic Pollution Role:PI $446,743.00 Closed Level:Federal

Grant: #5-R01-ES-10416-05-A0-S0-E0 Investigators:Nebert, Daniel 05-01-2000 -04-30-2006 National Institute of Environmental Health Sciences Molecular Genetics of Cd Toxicity Role:PI $1,721,250.00 Closed Level:Federal

Grant: #R21 ES015335 Investigators:Nebert, Daniel 12-15-2007 -11-30-2010 National Institute of Environmental Health Sciences Genetic Differences in PCB-Induced Behavior Role:PI $438,193.00 Closed Level:Federal

Grant: #P30 ES006096-16A1 Investigators:Caruso, Joseph; Deka, Ranjan; Embi, Peter; Greis, Kenneth; Ho, Shuk Mei; Lemasters, Grace; Medvedovic, Mario; Meller, Jaroslaw; Nebert, Daniel; Pinney, Susan; Puga, Alvaro; Rohs, Amy; Woo, Daniel 04-01-2008 -03-31-2013 National Institute of Environmental Health Sciences Environmental Genetics Role:Collaborator $8,028,782.00 Active Level:Federal

Grant: #T32 ES016646 Investigators:Nebert, Daniel 07-01-2008 -06-30-2014 National Institute of Environmental Health Sciences Gene-Environment Interaction Training Program Role:PI $1,861,830.00 Active Level:Federal

Grant: #R01 ES010807 Investigators:Nebert, Daniel; Puga, Alvaro; Xia, Ying 01-06-2011 -12-31-2015 National Institute of Environmental Health Sciences Molecular Mechanisms of Complex Mixture Toxicity Role:Collaborator $1,347,002.00 Active Level:Federal

Peer Reviewed Publications

McDermott J.;Geng X.;Jiang L.;Gálvez-Peralta M.;Chen F.;Nebert D.;Liu Z. (06-07-2016. ) Zinc-and bicarbonate-dependent ZIP8 transporter mediates selenite uptake.Oncotarget, , 7 (23 ) ,35327-35340 More Information

Nebert D.;Ingelman-Sundberg M. (03-01-2016. ) What do animal experiments tell us that in vitro systems cannot? The Human Toxome Project.Regulatory Toxicology and Pharmacology, , 75 ,1-4 More Information

Dong H.;Nebert D.;Bruford E.;Thompson D.;Joenje H.;Vasiliou V. (11-24-2015. ) Update of the human and mouse Fanconi anemia genes.Human genomics, , 9 ,32 More Information

Park J.H.;Hogrebe M.;Grüneberg M.;Duchesne I.;Von Der Heiden A.L.;Reunert J.;Schlingmann K.P.;Boycott K.M.;Beaulieu C.L.;Mhanni A.A.;Innes A.M.;Hörtnagel K.;Biskup S.;Gleixner E.M.;Kurlemann G.;Fiedler B.;Omran H.;Rutsch F.;Wada Y.;Tsiakas K.;Santer R.;Nebert D.W.;Rust S.;Marquardt T. (12-03-2015. ) SLC39A8 Deficiency: A Disorder of Manganese Transport and Glycosylation.American Journal of Human Genetics, , 97 (6 ) ,894-903 More Information

Boycott K.M.;Beaulieu C.L.;Kernohan K.D.;Gebril O.H.;Mhanni A.;Chudley A.E.;Redl D.;Qin W.;Hampson S.;Küry S.;Tetreault M.;Puffenberger E.G.;Scott J.N.;Bezieau S.;Reis A.;Uebe S.;Schumacher J.;Hegele R.A.;McLeod D.R.;Gálvez-Peralta M.;Majewski J.;Ramaekers V.T.;Nebert D.W.;Innes A.M.;Parboosingh J.S.;Abou Jamra R. (12-03-2015. ) Autosomal-Recessive Intellectual Disability with Cerebellar Atrophy Syndrome Caused by Mutation of t.American Journal of Human Genetics, , 97 (6 ) ,886-893 More Information

Brocker C.; Gonzalez F.; Monte A.; Nebert D.; Thompson D.; Vasiliou V. (01-01-2014. ) Improved drug therapy: triangulating phenomics with genomics and metabolomics.Human genomics, , 8 ,16 More Information

Jorge-Nebert L.;Zhang G.;Wilson K.;Jiang Z.;Butler R.;Gluckman J.;Pinney S.;Nebert D. (11-28-2016. ) Head-and-neck squamous cell carcinoma risk in smokers: no association detected between phenotype and.Human Genomics, , 10 (1 ) ,1-17 More Information

Schiering C.;Wincent E.;Metidji A.;Iseppon A.;Li Y.;Potocnik A.J.;Omenetti S.;Henderson C.J.;Wolf C.R.;Nebert D.W.;Stockinger B. (02-09-2017. ) Feedback control of AHR signalling regulates intestinal immunity.Nature, , 542 (7640 ) ,242-245 More Information

Zhang G.;Nebert D. (07-01-2017. ) Personalized medicine: Genetic risk prediction of drug response.Pharmacology and Therapeutics, , 175 ,75-90 More Information

Jorge-Nebert L.F.;Gálvez-Peralta M.;Landero Figueroa J.;Somarathna M.;Hojyo S.;Fukada T.;Nebert D.W. (01-01-2015. ) Comparing gene expression during cadmium uptake and distribution: untreated versus oral Cd-treated w.Toxicological sciences : an official journal of the Society of Toxicology, , 143 (1 ) ,26-35 More Information

Nebert D.W. (07-01-2017. ) Aryl hydrocarbon receptor (AHR): “pioneer member” of the basic-helix/loop/helix per-Arnt-sim (bHLH/P.Progress in Lipid Research, , 67 ,38-57 More Information

Brocker C.;Carpenter C.;Nebert D.;Vasiliou V. (08-01-2010. ) Evolutionary divergence and functions of the human acyl-CoA thioesterase gene ( ACOT ) family .Human Genomics, , 4 (6 ) ,411-420

Jackson B.C.;Nebert D.W.;Vasiliou V. (01-01-2010. ) Update of human and mouse matrix metalloproteinase families. Human genomics, , 4 (3 ) ,194-201

Jackson B.C.;Carpenter C.;Nebert D.W.;Vasiliou V. (01-01-2010. ) Update of human and mouse forkhead box (FOX) gene families. Human genomics, , 4 (5 ) ,345-352

Roberts R.;Nebert D.;Hickman J.;Richburg J.;Goldsworthy T. (01-01-1997. ) Perturbation of the mitosis/apoptosis balance: A fundamental mechanism in toxicology.Toxicological Sciences, , 38 (2 ) ,107-115 More Information

Guengerich F.; Juchau M.; Miller M.; Nebert D.; Raucy J. (01-01-1996. ) Drug metabolic enzymes in developmental toxicology.Toxicological Sciences, , 34 (2 ) ,165-175 More Information

Wolf C.;Spurr N.;Nebert D. (01-01-1992. ) Identification of genetic differences in debrisoquine hydroxylase activity.Hepatology, , 15 (2 ) ,360-360 More Information

Vasiliou V.;Liang H.;Puga A.;Nebert D. (01-01-1992. ) Autoregulation Plus Negative And Positive Control of Murine Cypla-1 Gene Expression and the [Ah] Bat.Journal of Basic and Clinical Physiology and Pharmacology, , 3 (Supplement ) ,12 More Information

Nebert D. (01-01-1980. ) Pharmacogenetics: An approach to understanding chemical and biologic aspects of cancer.Journal of the National Cancer Institute, , 64 (6 ) ,1279-1290 More Information

Nebert D. (08-22-1981. ) Clinical pharmacology: Possible clinical importance of genetic differences in drug metabolism.British Medical Journal (Clinical research ed.), , 283 (6290 ) ,537 More Information

Levitt R.;Fysh J.;Jensen N.;Nebert D. (12-01-1979. ) The Ah locus: Biochemical basis for genetic differences in brain tumor formation in mice .Genetics, , 92 (4 ) ,1205-1210

Pelkonen O.;Vahakangas K.;Nebert D. (01-01-1980. ) Binding of polycyclic aromatic hydrocarbons to dna: Comparison with mutagenesis and tumorigenesis.Journal of Toxicology and Environmental Health, , 6 (5-6 ) ,89-100 More Information

Nebert D.;Shum S. (01-01-1980. ) Reply to the letter of doctors Shepard and Fantel.Teratology, , 22 (3 ) ,349-350 More Information

Gene Superfamiles,Nomenclature,Pharmacogenetics,Pharmacogenomics

Academic - Dept Environ Health
31009 SW Country View Lane
Wilsonville  Oregon, 97070
Phone: 5036948482
dan.nebert@uc.edu