Erik B Nelson , MD

DR. ERIK NELSON is an Associate Professor of Clinical Psychiatry. His expertise is in the treatment and research of mood disorders, in particular major depression. Dr. Nelson received his medical degree and completed his general psychiatry residency at the University of Cincinnati College of Medicine.

Dr. Nelson’s main research interests have included major depression, psychotic depression, bipolar depression and antidepressant-induced sexual dysfunction. He is interested in developing new strategies for the treatment of depression, particularly psychotic depression and bipolar depression. He is also trying to find effective treatments for sexual dysfunction caused by SSRI antidepressants.

Medical Degree: University of Cincinnati College of Medicine

Residency: University of Cincinnati/University Hospital (General Psychiatry)

American Board of Psychiatry and Neurology (Psychiatry) (Certification Date: 11-17-1997 ) - (Recertification Date: to 08-19-2019 )

Psychiatry

Major Depressive Disorder

Treatment Resistant Depression

Psychiatry

Grant: #K23 MH067705 Investigators:Nelson, Erik 07-01-2004 -06-30-2010 National Institute of Mental Health Hypothalamo Pituitary Adrenocortical Axis Dysregulation and Phenomenology of Major Depression Role:PI $908,430.00 Closed Level:Federal

Grant: #005064-001 Investigators:Eliassen, James; Ficker, David; Nelson, Erik; Szaflarski, Jerzy 07-01-2007 -12-31-2009 Epilepsy Foundation Neurobiology of Depression and Suicidality in Epilepsy: A Functional MRI Study Role:Collaborator $50,000.00 Closed Level:Private Non-Profit

Grant: #3 K23MH067705-05S1 Investigators:Geracioti, Thomas; Herman, James; Keck, Paul; McElroy, Susan Lynn; Nelson, Erik; Shukla, Rakesh; Strakowski, Stephen 07-01-2009 -06-30-2010 National Institute of Mental Health Hypothalamic-Pituitary-Adrenal Axis Dysregulation & Phenomenology of Major Depression ARRA Supplement Role:PI $54,000.00 Closed Level:Federal

Grant: #K25 MH085103 Investigators:Adler, Caleb; Chu, Wen-Jang; Eliassen, James; Lee, Jing-Huei; Nasrallah, Henry; Nelson, Erik; Strakowski, Stephen 04-01-2010 -12-31-2013 National Institute of Mental Health Contrasting Glutamatergic Neurotransmission in Bipolar Disorder and Schizophrenia Role:Collaborator $495,850.00 Active Level:Federal

Grant: #URC Interdisciplinary awards AY2014-15 Investigators:Kissela, Brett; McCarthy, Michael; Nelson, Erik 05-01-2015 -04-30-2016 UC's University Research Council Chronic Stress, Partner Incongruence, and HPA Axis Activity in Stroke Caregiver Depression Role:Collaborator $25,000.00 Active Level:Internal UC

Grant: #229656 / TRD-1511-33227 Investigators:Nelson, Erik 02-01-2018 -10-31-2018 Patient-Centered Outcomes Research Institute Switching Versus Augmentation in Treatment Resistant Depression Role:PI $240,426.68 Active Level:Private Non-Profit

Grant: #Device Usage Agreement Investigators:Nelson, Erik 11-15-2018 -11-01-2021 Patient-Centered Outcomes Research Institute Augmentation versus Switch: comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders with Treatment Resistant Depression (ASCERTAIN-TRD)(NEURONETICS AGREEMENT) Role:PI $.00 Active Level:Private Non-Profit

Grant: #U01DA048525 Investigators:Dasenbrock-Gamm, Hanna; Kirley, Terence; Nelson, Erik; Norman, Andrew; Ridgway, William; Webster, Rose; Welge, Jeffrey 07-01-2019 -04-30-2022 National Institute on Drug Abuse First-In-Human Study of a Humanized Anti-Cocaine Monoclonal Antibody Role:Collaborator $4,770,702.00 Awarded Level:Federal

Grant: #REL-1017-310 02-01-2022 -02-12-2025 Relmada Therapeutics A Phase 3, Multicenter, Open-Label Study to Assess the Long-Term Safety of REL-1017 as a Treatment of Major Depressive Disorder (RELIANCE-OLS) Role:PI 232167.02 Hold Level:Industry

Grant: #REL-1017-310 02-01-2022 -02-12-2025 Relmada Therapeutics A Phase 3, Multicenter, Open-Label Study to Assess the Long-Term Safety of REL-1017 as a Treatment of Major Depressive Disorder (RELIANCE-OLS) Role:PI 232167.02 Hold Level:Industry

Peer Reviewed Publications

Guerdjikova, Anna I; McElroy, Susan L; Welge, Jeffrey A; Nelson, Erik; Keck, Paul E; Hudson, James I (2009. ) Lamotrigine in the treatment of binge-eating disorder with obesity: a randomized, placebo-controlled monotherapy trial.International clinical psychopharmacology, , 24 (3 ) ,150-8 More Information

McElroy, Susan L; Nelson, Erik B; Welge, Jeffrey A; Kaehler, Laura; Keck, Paul E (2008. ) Olanzapine in the treatment of pathological gambling: a negative randomized placebo-controlled trial. The Journal of clinical psychiatry, , 69 (3 ) ,433-40

Guerdjikova, Anna I; McElroy, Susan L; Kotwal, Renu; Welge, Jeffrey A; Nelson, Erik; Lake, Katie; Alessio, David D (2008. ) High-dose escitalopram in the treatment of binge-eating disorder with obesity: a placebo-controlled monotherapy trial.Human psychopharmacology, , 23 (1 ) ,1-11 More Information

McElroy, Susan L; Guerdjikova, Anna; Kotwal, Renu; Welge, Jeffrey A; Nelson, Erik B; Lake, Kathleen A; Keck, Paul E; Hudson, James I (2007. ) Atomoxetine in the treatment of binge-eating disorder: a randomized placebo-controlled trial. The Journal of clinical psychiatry, , 68 (3 ) ,390-8

McElroy, Susan L; Kotwal, Renu; Guerdjikova, Anna I; Welge, Jeffrey A; Nelson, Erik B; Lake, Kathleen A; D (2006. ) Zonisamide in the treatment of binge eating disorder with obesity: a randomized controlled trial. The Journal of clinical psychiatry, , 67 (12 ) ,1897-906

DelBello, Melissa P; Kowatch, Robert A; Adler, Caleb M; Stanford, Kevin E; Welge, Jeffrey A; Barzman, Drew H; Nelson, Erik; Strakowski, Stephen M (2006. ) A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent mania.Journal of the American Academy of Child and Adolescent Psychiatry, , 45 (3 ) ,305-13 More Information

McElroy, Susan L; Kotwal, Renu; Malhotra, Shishuka; Nelson, Erik B; Keck, Paul E; Nemeroff, Charles B (2004. ) Are mood disorders and obesity related? A review for the mental health professional. The Journal of clinical psychiatry, , 65 (5 ) ,634-51, quiz 730

Dunsieth, Neal W; Nelson, Erik B; Brusman-Lovins, Lori A; Holcomb, Jeff L; Beckman, DeAnna; Welge, Jeffrey A; Roby, David; Taylor, Purcell; Soutullo, Cesar A; McElroy, Susan L (2004. ) Psychiatric and legal features of 113 men convicted of sexual offenses. The Journal of clinical psychiatry, , 65 (3 ) ,293-300

McElroy, Susan L; Kotwal, Renu; Hudson, James I; Nelson, Erik B; Keck, Paul E (2004. ) Zonisamide in the treatment of binge-eating disorder: an open-label, prospective trial. The Journal of clinical psychiatry, , 65 (1 ) ,50-6

McElroy, Susan L; Hudson, James I; Malhotra, Shishuka; Welge, Jeffrey A; Nelson, Erik B; Keck, Paul E (2003. ) Citalopram in the treatment of binge-eating disorder: a placebo-controlled trial. The Journal of clinical psychiatry, , 64 (7 ) ,807-13

Keck, Paul E; Nelson, Erik B; McElroy, Susan L (2003. ) Advances in the pharmacologic treatment of bipolar depression. Biological psychiatry, , 53 (8 ) ,671-9

Cerullo, Michael A; Eliassen, James C; Smith, Christopher T; Fleck, David E; Nelson, Erik B; Strawn, Jeffrey R; Lamy, Martine; DelBello, Melissa P; Adler, Caleb M; Strakowski, Stephen M (2014. ) Bipolar I disorder and major depressive disorder show similar brain activation during depression.Bipolar disorders, , More Information

Allendorfer, Jane B; Heyse, Heidi; Mendoza, Lucy; Nelson, Erik B; Eliassen, James C; Storrs, Judd M; Szaflarski, Jerzy P (2014. ) Physiologic and cortical response to acute psychosocial stress in left temporal lobe epilepsy - a pilot cross-sectional fMRI study.Epilepsy & behavior : E&B, , 36 ,115-23 More Information

Papakostas, George I; Shelton, Richard C; Zajecka, John M; Etemad, Bijan; Rickels, Karl; Clain, Alisabet; Baer, Lee; Dalton, Elizabeth D; Sacco, Garret R; Schoenfeld, David; Pencina, Michael; Meisner, Allison; Bottiglieri, Teodoro; Nelson, Erik; Mischoulon, David; Alpert, Jonathan E; Barbee, James G; Zisook, Sidney; Fava, Maurizio (2012. ) L-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trials.The American journal of psychiatry, , 169 (12 ) ,1267-74 More Information

Nelson, Erik B (2012. ) Psychotic depression--beyond the antidepressant/antipsychotic combination.Current psychiatry reports, , 14 (6 ) ,619-23 More Information

DelBello, Melissa P; Kowatch, Robert A; Adler, Caleb M; Stanford, Kevin E; Welge, Jeffrey A; Barzman, Drew H; Nelson, Erik; Strakowski, Stephen M (2006. ) A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent mania.Journal of the American Academy of Child and Adolescent Psychiatry, , 45 (3 ) ,305-13 More Information

Dunsieth, Neal W; Nelson, Erik B; Brusman-Lovins, Lori A; Holcomb, Jeff L; Beckman, DeAnna; Welge, Jeffrey A; Roby, David; Taylor, Purcell; Soutullo, Cesar A; McElroy, Susan L (2004. ) Psychiatric and legal features of 113 men convicted of sexual offenses. The Journal of clinical psychiatry, , 65 (3 ) ,293-300

Guerdjikova, Anna I; McElroy, Susan L; Winstanley, Erin L; Nelson, Eric B; Mori, Nicole; McCoy, Jessica; Keck, Paul E; Hudson, James I (2012. ) Duloxetine in the treatment of binge eating disorder with depressive disorders: a placebo-controlled trial.The International journal of eating disorders, , 45 (2 ) ,281-9 More Information

Nelson, E B; Shah, V N; Welge, J A; Keck, P E (2001. ) A placebo-controlled, crossover trial of granisetron in SRI-induced sexual dysfunction. The Journal of clinical psychiatry, , 62 (6 ) ,469-73

McElroy, S L; Soutullo, C A; Taylor, P; Nelson, E B; Beckman, D A; Brusman, L A; Ombaba, J M; Strakowski, S M; Keck, P E (1999. ) Psychiatric features of 36 men convicted of sexual offenses. The Journal of clinical psychiatry, , 60 (6 ) ,414-20; quiz 421-2

Nelson, E B; Sax, K W; Strakowski, S M (1998. ) Attentional performance in patients with psychotic and nonpsychotic major depression and schizophrenia.The American journal of psychiatry, , 155 (1 ) ,137-9 More Information

Nelson, E B; Keck, P E; McElroy, S L (1997. ) Resolution of fluoxetine-induced sexual dysfunction with the 5-HT3 antagonist granisetron. The Journal of clinical psychiatry, , 58 (11 ) ,496-7

Nelson, E; Brusman, L; Holcomb, J; Soutullo, C; Beckman, D; Welge, J A; Kuppili, N; McElroy, S L (2001. ) Divalproex sodium in sex offenders with bipolar disorders and comorbid paraphilias: an open retrospective study. Journal of affective disorders, , 64 (2-3 ) ,249-55

Goodman, Adam M; Allendorfer, Jane B; Heyse, Heidi; Szaflarski, Basia A; Eliassen, James C; Nelson, Erik B; Storrs, Judd M; Szaflarski, Jerzy P (2019. ) Neural response to stress and perceived stress differ in patients with left temporal lobe epilepsy.Human brain mapping, , 40 (12 ) ,3415-3430 More Information

Wade, Natasha E; Padula, Claudia B; Anthenelli, Robert M; Nelson, Erik; Eliassen, James; Lisdahl, Krista M (2017. ) Blunted amygdala functional connectivity during a stress task in alcohol dependent individuals: A pilot study.Neurobiology of stress, , 7 ,74-79 More Information

Padula, Claudia B; Anthenelli, Robert M; Eliassen, James C; Nelson, Erik; Lisdahl, Krista M (2015. ) Gender effects in alcohol dependence: an fMRI pilot study examining affective processing.Alcoholism, clinical and experimental research, , 39 (2 ) ,272-81 More Information

Wade N.; Padula C.; Anthenelli R.; Nelson E.; Eliassen J.; Lisdahl K. (12-01-2017. ) Blunted amygdala functional connectivity during a stress task in alcohol dependent individuals: A pi.Neurobiology of Stress, , 7 ,74-79 More Information

Papakostas G.I.; Shelton R.C.; Zajecka J.M.; Etemad B.; Rickels K.; Clain A.; Baer L.; Dalton E.D.; Sacco G.R.; Schoenfeld D.; Pencina M.; Meisner A.; Bottiglieri T.; Nelson E.; Mischoulon D.; Alpert J.E.; Barbee J.G.; Zisook S.; Fava M. (12-01-2012. ) L-methylfolate as adjunctive therapy for SSRI-resistant major depression: Results of two randomized,.American Journal of Psychiatry, , 169 (12 ) ,1267-1274 More Information

Herman J.P.; Figueiredo H.F.; Mueller N.K.; Ostrander M.M.; Zhang R.; Tauchi M.; Choi D.C.; Furay A.R.; Evanson N.K.; Nelson E.B.; Ulrich-Lai Y.M. (12-01-2007. ) Neurochemical systems regulating the hypothalamo-pituitary-adrenocortical axis.Handbook of Neurochemistry and Molecular Neurobiology: Behavioral Neurochemistry, Neuroendocrinology and Molecular Neurobiology, , 513-569 More Information

Nelson E.; McElroy S. (01-01-1997. ) Psychotic depression: A guide to drug choice.CNS Drugs, , 8 (6 ) ,457-473 More Information

Nelson, E B; Rielage, E; Welge, J A; Keck, P E (2001. ) An open trial of olanzapine in the treatment of patients with psychotic depression.Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, , 13 (3 ) ,147-51 More Information

McElroy, S L; Casuto, L S; Nelson, E B; Lake, K A; Soutullo, C A; Keck, P E; Hudson, J I (2000. ) Placebo-controlled trial of sertraline in the treatment of binge eating disorder.The American journal of psychiatry, , 157 (6 ) ,1004-6 More Information

Nelson E. (01-01-2008. ) Role of antiepileptic drugs in the treatment of major depressive disorder.Antiepileptic Drugs to Treat Psychiatric Disorders, , 177-186 More Information

Invited Presentations

Amy Bischoff, MD; Corey Keeton, MD; Erik Nelson, MD (04-21-2021. ) A Case of Self-injurious Behavior in a Patient with Intellectual and Developmental Disability .Grand Rounds, University of Cincinnati College of Medicine, Department of Psychiatry and Behavioral Neuroscience. Level:Department

Depression, Mood disorders ,Diseases(MeSH C),Chemicals and Drugs(MeSH D),Psychiatry and Psychology(MeSH F),Nervous System Diseases(MeSH C10),Neurotransmitters and Neurotransmitter Agents(MeSH D14),Central Nervous System Agents(MeSH D15),Mental Disorders(MeSH F03)

Erik Nelson, MD, is a physician with University of Cincinnati Physicians.

Practice Location:
UC Health Psychiatry (Stetson Building)
260 Stetson Street, Suite 3200
Cincinnati, Ohio 45219

Clinical Specialties:
Psychiatry/Psychology, Mood Disorders, Depression

To make an appointment, please call (513) 475-8000.

 

Academic - UC Department of Psychiatry and Behavioral Neuroscience
PO Box 670559
Cincinnati  Ohio, 45267-0559
Phone: 513-558-7700
erik.nelson@uc.edu