Laura Ngwenya

Laura Benjamin Ngwenya , MD,PhD

Associate Professor of Clinical

Director of Neurotrauma

Medical Sciences Building
231 Albert Sabin Way
Room 5251
Cincinnati, Ohio 45267
Phone 513-558-0434
Email Laura.Ngwenya@uc.edu

Professional Summary

Associate Professor of Neurosurgery
Director of Neurotrauma
Surgical Director, Neurosciences Intensive Care Unit

Education

Bachelor's Degree: Rutgers University

Doctor of Philosophy: Boston University

Medical Degree: Boston University

Neurological Surgery Residency: The Ohio State University

Neurotrauma and Neurocritical Care Fellowship: University of California San Francisco

Certifications

American Board of Neurological Surgery (Certification Date: 11-02-2019 )

Clinical Interests

Neurosurgery

N/A

Stroke

Acute Head Bleeds

Acute Stroke

Arachnoid Cysts

Arnold-Chiari Malformation

Back Injuries

Benign Peripheral Nerve Tumor

Brain Abscess

Brain Concussion

Brain Hemorrhage

Brain Injuries

Carpal Tunnel Syndrome

Cerebral Contusion

Cerebral Hemorrhage

Cerebrovascular Trauma

Cervical Radiculopathy (pinched nerve)

Cervical Spondylosis

Cervicitis

Chiari Malformation

Concussion

Degenerative Spine Disease

Head Injury

Head Trauma

Hemorrhagic Stroke

Herniated Discs

Hydrocephalus

Intervertebral Disc Degeneration

Intervertebral Disc Displacement

Intracerebral Hemorrhage (ICH)

Intracranial Hematoma

Intracranial Hemorrhages

Intraventricular Hemorrhage

Lumbar Radiculopathy

Lumbar Spinal Stenosis

Mild Traumatic Brain Injury

Neck Pain

Neck/Spine Injury

Normal Pressure Hydrocephalus

Peripheral Nerve Disorders

Peripheral Nerve Tumors

Peripheral Nervous System Disease

Pinched Nerve

Pseudotumor Cerebri (Idiopathic Intracranial Hypertension)

Sciatica

Severe Brain Injury

Severe Traumatic Brain Injury

Skull Fractures

Spinal Cord Compression

Spinal Cord Injuries

Spinal Cord Tumor

Spinal Disease

Spinal Disorders

Spinal Fluid Leaks

Spinal Fractures

Spinal Fusion

Spinal Injuries

Spinal Stenosis

Spinal Tumors

Spine Infections

Subarachnoid Hemorrhage

Subdural Hematoma

Temporal Bone Fractures

Thoracic and Lumbar Spine Disorders

Traumatic Brain Injury (TBI)

Traumatic Spine Fractures

Specialities

Neurological Surgery

Research and Practice Interests

Neurotrauma, Traumatic brain injury, Spinal injury, General Neurosurgery

Dr. Ngwenya has a clinical and research interest in neurotrauma, specifically, traumatic brain injury. Her clinical research involves identifying subsets of traumatic brain injured patients for targeted intervention.  Her basic science laboratory focuses on alterations in adult neurogenesis, spreading depolarizations, and identifying substrates that underlie cognitive deficits after traumatic brain injury.

Research Support

Grant: #HOPES Investigators:Andaluz, Norberto; Hartings, Jed; Hinzman, Jason; Ngwenya, Laura 05-01-2015 -12-31-2018 Vivian L Smith Foundation for Neurological Research HypOthermia for Patients requiring Evacuation of Subdural Hematoma (HOPES): a Multicenter, Randomized Clinical Trial Role:PI $77,463.89 Active Level:Private Non-Profit

Grant: #2017 Grant Investigators:McGuire, Jennifer; Ngwenya, Laura 09-01-2017 -08-31-2019 Local Initiative for Excellence (L.I.F.E.) Identifying the genetic risk underlying poor cognitive recovery after traumatic brain injury Role:PI $50,000.00 Active Level:Private Non-Profit

Grant: #K08NS110988 Investigators:Ngwenya, Laura 04-15-2019 -01-31-2024 National Institute of Neurological Disorders and Stroke Spreading depolarizations and brain dysfunction following traumatic brain injury Role:PI $201,014.00 Awarded Level:Federal

Grant: #Medical Student Summer Research Fellowship (MSSRF) Investigators:Ngwenya, Laura 06-10-2019 -08-10-2019 Neurosurgery Research and Education Foundation The Effects of Cortical Spreading Depolarizations on the Hippocampus Role:PI $2,500.00 Awarded Level:Private Non-Profit

Grant: #UFRA-141 / Gift Funding / CA-0132058 Investigators:Adeoye, Opeolu; Ngwenya, Laura 09-01-2018 -08-31-2020 University of California, San Francisco TRACK-TBI Imaging, Physiologic, and Molecular Biomarkers of Post-TBI Epileptogenesis in Humans: Toward a CURE (TRACK-TBI CURE) Role:PI $263,000.00 Active Level:Institution of Higher Education

Grant: #10222sc / W81XWH-14-2-0176 Investigators:Adeoye, Opeolu; Ngwenya, Laura 09-30-2016 -09-29-2019 Department of the Army Medical Research Acquisition Activity TBI Endpoints Development (TED) Role:PI $161,200.00 Active Level:Federal

Grant: #W81XWH-20-1-0830 Investigators:Goodman, Michael; Hartings, Jed; McGuire, Jennifer; Ngwenya, Laura 09-01-2020 -08-31-2022 Department of the Army Medical Research Acquisition Activity DM190198 - Rapid Ketone Infusion to Prevent Brain Energy Depletion and Secondary Brain Injury in Severe TBI with Hemorrhagic Shock Role:Collaborator $723,710.00 Awarded Level:Federal

Grant: #RSA 12234sc / NFL A131769 Investigators:Ngwenya, Laura 04-01-2020 -06-30-2021 National Football League Scientific Advisory Board Transforming Research and Clinical Knowledge in Traumatic Brain Injury (Track TBI Longitudinal Study) Role:PI $56,000.00 Awarded Level:Industry

Grant: #CS-2018-0009 / W81XWH-19-C-0071 Investigators:Ngwenya, Laura 07-15-2020 -07-14-2022 Department of the Army Medical Research and Materiel Command Clinical Evaluation of the i-STAT TBI Test (i-STAT Study) Role:PI $82,311.00 Active Level:Federal

Grant: #581679/U01NS114140 Investigators:Ngwenya, Laura 03-15-2020 -02-28-2021 University of Pennsylvania Clinical Validation of Serum Neurofilament Light as a Biomarker of Traumatic Axonal Injury Role:PI 3200.00 Hold Level:Higher Education

Grant: #W81XWH-21-C-0075 Investigators:Foreman, Brandon; Hartings, Jed; Jandarov, Roman; Ngwenya, Laura 09-20-2021 -09-19-2024 Department of the Army Medical Research Acquisition Activity JW200215 - Improving Neurotrauma by Depolarization Inhibition with Combination Therapy (INDICT): a Phase 2 Randomized Trial Role:Collaborator 0.00 Hold Level:Federal

Grant: #578105 / W81XWH-19-1-0861 09-30-2019 -09-29-2020 Department of the Army Medical Research Acquisition Activity TRACK-TBI Epileptogenesis Project Role:PI 0.00 Hold Level:Federal

Grant: #578105 / W81XWH-19-1-0861 09-30-2019 -09-29-2020 Department of the Army Medical Research Acquisition Activity TRACK-TBI Epileptogenesis Project Role:PI 0.00 Hold Level:Federal

Publications

Peer Reviewed Publications

Estrada, Larissa I; Robinson, Amy A; Amaral, Ana C; Giannaris, Eustathia L; Heyworth, Nadine C; Mortazavi, Farzad; Ngwenya, Laura B; Roberts, Debra E; Cabral, Howard J; Killiany, Ronald J; Rosene, Douglas L (2017. ) Evaluation of Long-Term Cryostorage of Brain Tissue Sections for Quantitative Histochemistry.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, , 65 (3 ) ,153-171 More Information

Ngwenya, Laura B; Burke, John F; Manley, Geoffrey T (2016. ) Brain Tissue Oxygen Monitoring and the Intersection of Brain and Lung: A Comprehensive Review.Respiratory care, , 61 (9 ) ,1232-44 More Information

Burke, John Frederick; Yue, John K; Ngwenya, Laura Benjamin; Winkler, Ethan A; Talbott, Jason; Pan, Jonathan; Ferguson, Adam; Beattie, Michael; Bresnahan, Jacqueline; Haefeli, Jenny; Whetstone, William; Suen, Catherine; Huang, Michael C; Manley, Geoffrey T; Tarapore, Phiroz E; Dhall, Sanjay S (2016. ) 182?Ultra-Early (<12 Hours) Decompression Improves Recovery After Spinal Cord Injury Compared to Early (12-24 Hours) Decompression.Neurosurgery, , 63 Suppl 1 ,172 More Information

Ngwenya, Laura B; Prevedello, Luciano M; Youssef, Patrick P (2016. ) Concomitant epidural and subdural spinal abscess: a case report.The spine journal : official journal of the North American Spine Society, , 16 (4 ) ,e275-82 More Information

Ngwenya, Laura B; Heyworth, Nadine C; Shwe, Yamin; Moore, Tara L; Rosene, Douglas L (2015. ) Age-related changes in dentate gyrus cell numbers, neurogenesis, and associations with cognitive impairments in the rhesus monkey.Frontiers in systems neuroscience, , 9 ,102 More Information

Ngwenya, Laura B; Chiocca, E Antonio (2013. ) Editorial: postoperative ischemia.Journal of neurosurgery, , 118 (4 ) ,799-800; discussion More Information

Ngwenya, Laura B; Chiocca, E Antonio Do meningioma patients benefit from antiepileptic drug treatment?.World neurosurgery, , 79 (3-4 ) ,433-4 More Information

Ngwenya, Laura B; Chiocca, E Antonio (2012. ) Editorial: meningioma and radiotherapy.Journal of neurosurgery, , 117 (4 ) ,666-8 More Information

Ngwenya, Laura B; Chiocca, E Antonio Treatment for paragangliomas: passing the test of time.World neurosurgery, , 77 (5-6 ) ,639-41 More Information

Ngwenya, Laura B; Chiocca, E Antonio (2011. ) Extent of resection.Journal of neurosurgery, , 115 (1 ) ,1-2; discussion 2 More Information

Ngwenya, Laura B; Rosene, Douglas L; Peters, Alan (2008. ) An ultrastructural characterization of the newly generated cells in the adult monkey dentate gyrus.Hippocampus, , 18 (2 ) ,210-20 More Information

Ngwenya, Laura B; Peters, Alan; Rosene, Douglas L (2006. ) Maturational sequence of newly generated neurons in the dentate gyrus of the young adult rhesus monkey.The Journal of comparative neurology, , 498 (2 ) ,204-16 More Information

Ngwenya, Laura B; Peters, Alan; Rosene, Douglas L (2005. ) Light and electron microscopic immunohistochemical detection of bromodeoxyuridine-labeled cells in the brain: different fixation and processing protocols.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, , 53 (7 ) ,821-32 More Information

Ngwenya, Laura B; Suen, Catherine G; Tarapore, Phiroz E; Manley, Geoffrey T; Huang, Michael C (2017. ) Safety and cost efficiency of a restrictive transfusion protocol in patients with traumatic brain injury.Journal of neurosurgery, , 1-8 More Information

Yue, John K; Ngwenya, Laura B; Upadhyayula, Pavan S; Deng, Hansen; Winkler, Ethan A; Burke, John F; Lee, Young M; Robinson, Caitlin K; Ferguson, Adam R; Lingsma, Hester F; Cnossen, Maryse C; Pirracchio, Romain; Korley, Frederick K; Vassar, Mary J; Yuh, Esther L; Mukherjee, Pratik; Gordon, Wayne A; Valadka, Alex B; Okonkwo, David O; Manley, Geoffrey T (2017. ) Emergency department blood alcohol level associates with injury factors and six-month outcome after uncomplicated mild traumatic brain injury.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, , More Information

Yue, John K; Burke, John F; Upadhyayula, Pavan S; Winkler, Ethan A; Deng, Hansen; Robinson, Caitlin K; Pirracchio, Romain; Suen, Catherine G; Sharma, Sourabh; Ferguson, Adam R; Ngwenya, Laura B; Stein, Murray B; Manley, Geoffrey T; Tarapore, Phiroz E (2017. ) Selective Serotonin Reuptake Inhibitors for Treating Neurocognitive and Neuropsychiatric Disorders Following Traumatic Brain Injury: An Evaluation of Current Evidence.Brain sciences, , 7 (8 ) , More Information

Martin, Grace E; Carroll, Christopher P; Plummer, Zach J; Millar, D A; Pritts, Timothy A; Makley, Amy T; Joseph, Bellal A; Ngwenya, Laura B; Goodman, Michael D (2017. ) Safety and Efficacy of Brain Injury Guidelines at a Level III Trauma Center.The journal of trauma and acute care surgery, , More Information

Hartings, Jed A; Ngwenya, Laura B; Carroll, Christopher P; Foreman, Brandon (2018. ) Letter to the Editor. Ketamine sedation for the suppression of spreading depolarizations.Journal of neurosurgery, , 1-2 More Information

McGuire, Jennifer L; DePasquale, Erica A K; Watanabe, Miki; Anwar, Fatima; Ngwenya, Laura B; Atluri, Gowtham; Romick-Rosendale, Lindsey E; McCullumsmith, Robert E; Evanson, Nathan K (2018. ) Chronic Dysregulation of Cortical and Subcortical Metabolism After Experimental Traumatic Brain Injury.Molecular neurobiology, , More Information

Foreman, Brandon; Ngwenya, Laura B; Stoddard, Erica; Hinzman, Jason M; Andaluz, Norberto; Hartings, Jed A (2018. ) Safety and Reliability of Bedside, Single Burr Hole Technique for Intracranial Multimodality Monitoring in Severe Traumatic Brain Injury.Neurocritical care, , More Information

Hartings, Jed A; Ngwenya, Laura B; Watanabe, Tomas; Foreman, Brandon (2018. ) Commentary: Detecting Cortical Spreading Depolarization with Full Band Scalp Electroencephalography: An Illusion?.Frontiers in systems neuroscience, , 12 ,19 More Information

Ngwenya, Laura B; Mazumder, Sarmistha; Porter, Zachary R; Minnema, Amy; Oswald, Duane J; Farhadi, H Francis (2018. ) Implantation of Neuronal Stem Cells Enhances Object Recognition without Increasing Neurogenesis after Lateral Fluid Percussion Injury in Mice.Stem cells international, , 2018 ,4209821 More Information

Ngwenya, Laura B; Gardner, Raquel C; Yue, John K; Burke, John F; Ferguson, Adam R; Huang, Michael C; Winkler, Ethan A; Pirracchio, Romain; Satris, Gabriela G; Yuh, Esther L; Mukherjee, Pratik; Valadka, Alex B; Okonkwo, David O; Manley, Geoffrey T (2018. ) Concordance of common data elements for assessment of subjective cognitive complaints after mild-traumatic brain injury: a TRACK-TBI Pilot Study.Brain injury, , 32 (9 ) ,1071-1078 More Information

Wright, James M; Gerges, Christina; Shammassian, Berje; Labak, Collin M; Herring, Eric Z; Miller, Benjamin; Alkhachroum, Ayham; Kottapally, Mohan; Huang Wright, Christina; Rodgers, Richard B; Sedney, Cara; Ngwenya, Laura B; Stippler, Martina; Sieg, Emily; Babu, Maya A; Hoffer, Alan; Hejal, Rana (2021. ) Prone Position Ventilation in Neurologically Ill Patients: A Systematic Review and Proposed Protocol.Critical care medicine, , More Information

Robinson, David; Pyle, Logan; Foreman, Brandon; Ngwenya, Laura B; Adeoye, Opeolu; Woo, Daniel; Kreitzer, Natalie (2020. ) Factors Associated with Early versus Delayed Expansion of Acute Subdural Hematomas Initially Managed Conservatively.Journal of neurotrauma, , More Information

Matur, Abhijith V; Ngwenya, Laura B; Prestigiacomo, Charles J (2020. ) The surgical history of head injury in motor vehicle collision.Journal of neurosurgery, , 1-7 More Information

Barhorst, Kinsey A; Alfawares, Yara; McGuire, Jennifer L; Danzer, Steve C; Hartings, Jed A; Ngwenya, Laura B (2020. ) Remote and Persistent Alterations in Glutamate Receptor Subunit Composition Induced by Spreading Depolarizations in Rat Brain.Cellular and molecular neurobiology, , More Information

Shah, Sanjit; Yang, George L; Le, Diana T; Gerges, Christina; Wright, James M; Parr, Ann M; Cheng, Joseph S; Ngwenya, Laura B (2020. ) Examining the Emergency Medical Treatment and Active Labor Act: impact on telemedicine for neurotrauma.Neurosurgical focus, , 49 (5 ) ,E8 More Information

Le, Diana T; Barhorst, Kinsey A; Castiglione, James; Yang, George L; Shah, Sanjit J; Harlan, Sarah S; Keegan, Shaun P; Jandarov, Roman A; Ngwenya, Laura B; Prestigiacomo, Charles J (2020. ) Blunt cerebrovascular injury in the geriatric population.Neurosurgical focus, , 49 (4 ) ,E10 More Information

Rath, Kelly; Kreitzer, Natalie; Schlichter, Erika; Lopez, Omar; Ferioli, Simona; Ngwenya, Laura B; Foreman, Brandon (2020. ) The Experience of a Neurocritical Care Admission and Discharge for Patients and Their Families: A Qualitative Analysis.The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, , 52 (4 ) ,179-185 More Information

Rhame, Katherine; Le, Diana; Ventura, Amanda; Horner, Amy; Andaluz, Norberto; Miller, Christopher; Stolz, Uwe; Ngwenya, Laura B; Adeoye, Opeolu; Kreitzer, Natalie (2020. ) Management of the mild traumatic brain injured patient using a multidisciplinary observation unit protocol.The American journal of emergency medicine, , More Information

Porter, Zachary R; Mejia-Munne, Juan C; Krueger, Bryan M; Kosty, Jennifer A; Ngwenya, Laura B (2020. ) Sacral Rheumatoid Nodule: An Unusual Indication for Coccygectomy.Case reports in surgery, , 2020 ,2757625 More Information

Kreitzer, Natalie; Bakas, Tamilyn; Kurowski, Brad; Lindsell, Christopher J; Ferioli, Simona; Foreman, Brandon; Ngwenya, Laura B; Thomas, Stephanie; Keegan, Sara; Adeoye, Opeolu The Experience of Caregivers Following a Moderate to Severe Traumatic Brain Injury Requiring ICU Admission.The Journal of head trauma rehabilitation, , 35 (3 ) ,E299-E309 More Information

Rhame, Katherine; Le, Diana; Horner, Amy; Thomas, Andrea; Foreman, Brandon P; Kreitzer, Natalie P; Ngwenya, Laura B (2020. ) Implementation of a Neurotrauma Hotline for post-hospital continuity of care.Acta neurologica Scandinavica, , 141 (4 ) ,351-354 More Information

Hartings, Jed A; Andaluz, Norberto; Bullock, M Ross; Hinzman, Jason M; Mathern, Bruce; Pahl, Clemens; Puccio, Ava; Shutter, Lori A; Strong, Anthony J; Vagal, Achala; Wilson, J Adam; Dreier, Jens P; Ngwenya, Laura B; Foreman, Brandon; Pahren, Laura; Lingsma, Hester; Okonkwo, David O (2020. ) Prognostic Value of Spreading Depolarizations in Patients With Severe Traumatic Brain Injury.JAMA neurology, , 77 (4 ) ,489-499 More Information

Ngwenya, Laura B (2020. ) Commentary: Concussion Guidelines Step 2: Evidence for Subtype Classification.Neurosurgery, , 86 (1 ) ,E1 More Information

McGuire, Jennifer L; Correll, Erika A; Lowery, Alexandra C; Rhame, Katherine; Anwar, Fatima N; McCullumsmith, Robert E; Ngwenya, Laura B (2019. ) Pioglitazone improves working memory performance when administered in chronic TBI.Neurobiology of disease, , 132 ,104611 More Information

Dossani, Rimal H; Terrell, Danielle; Kosty, Jennifer A; Ross, Robert C; Demand, Audrey; Wild, Elizabeth; Peterson, Racheal; Ngwenya, Laura B; Benzil, Deborah L; Notarianni, Christina (2019. ) Gender disparities in academic rank achievement in neurosurgery: a critical assessment.Journal of neurosurgery, , 1-6 More Information

Khalid, Fatima; Yang, George L; McGuire, Jennifer L; Robson, Matthew J; Foreman, Brandon; Ngwenya, Laura B; Lorenz, John N (2019. ) Autonomic dysfunction following traumatic brain injury: translational insights.Neurosurgical focus, , 47 (5 ) ,E8 More Information

Robinson, Michael W; Prestigiacomo, Charles J; Ngwenya, Laura B (2021. ) Commentary: Intracerebral Hemorrhage Volume Reduction and Timing of Intervention Versus Functional Benefit and Survival in the MISTIE III and STICH Trials.Neurosurgery, , 88 (5 ) ,E394-E395 More Information

Burke, John F; Yue, John K; Ngwenya, Laura B; Winkler, Ethan A; Talbott, Jason F; Pan, Jonathan Z; Ferguson, Adam R; Beattie, Michael S; Bresnahan, Jacqueline C; Haefeli, Jenny; Whetstone, William D; Suen, Catherine G; Huang, Michael C; Manley, Geoffrey T; Tarapore, Phiroz E; Dhall, Sanjay S (2019. ) In Reply: Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury.Neurosurgery, , 85 (2 ) ,E401-E402 More Information

Xu, Linda B; Yue, John K; Korley, Frederick; Puccio, Ava M; Yuh, Esther L; Sun, Xiaoying; Rabinowitz, Miri; Vassar, Mary J; Taylor, Sabrina R; Winkler, Ethan A; Puffer, Ross C; Deng, Hansen; McCrea, Michael; Stein, Murray B; Robertson, Claudia S; Levin, Harvey S; Dikmen, Sureyya; Temkin, Nancy R; Giacino, Joseph T; Mukherjee, Pratik; Wang, Kevin K W; Okonkwo, David O; Markowitz, Amy J; Jain, Sonia; Manley, Geoffrey T; Diaz-Arrastia, Ramon (2021. ) High-Sensitivity C-Reactive Protein is a Prognostic Biomarker of Six-Month Disability after Traumatic Brain Injury: Results from the TRACK-TBI Study.Journal of neurotrauma, , 38 (7 ) ,918-927 More Information

Burke, John F; Yue, John K; Ngwenya, Laura B; Winkler, Ethan A; Talbott, Jason F; Pan, Jonathan Z; Ferguson, Adam R; Beattie, Michael S; Bresnahan, Jacqueline C; Haefeli, Jenny; Whetstone, William D; Suen, Catherine G; Huang, Michael C; Manley, Geoffrey T; Tarapore, Phiroz E; Dhall, Sanjay S (2019. ) Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury.Neurosurgery, , 85 (2 ) ,199-203 More Information

Levin, Harvey S; Temkin, Nancy R; Barber, Jason; Nelson, Lindsay D; Robertson, Claudia; Brennan, Jeffrey; Stein, Murray B; Yue, John K; Giacino, Joseph T; McCrea, Michael A; Diaz-Arrastia, Ramon; Mukherjee, Pratik; Okonkwo, David O; Boase, Kim; Markowitz, Amy J; Bodien, Yelena; Taylor, Sabrina; Vassar, Mary J; Manley, Geoffrey T ; Adeoye, Opeolu; Badjatia, Neeraj; Bullock, M Ross; Chesnut, Randall; Corrigan, John D; Crawford, Karen; Dikmen, Sureyya; Duhaime, Ann-Christine; Ellenbogen, Richard; Feeser, V Ramana; Ferguson, Adam R; Foreman, Brandon; Gardner, Raquel; Gaudette, Etienne; Gonzalez, Luis; Gopinath, Shankar; Gullapalli, Rao; Hemphill, J Claude; Hotz, Gillian; Jain, Sonia; Keene, C Dirk; Korley, Frederick K; Kramer, Joel; Kreitzer, Natalie; Lindsell, Chris; Machamer, Joan; Madden, Christopher; Martin, Alastair; McAllister, Thomas; Merchant, Randall; Nolan, Amber; Ngwenya, Laura B; Noel, Florence; Palacios, Eva; Puccio, Ava; Rabinowitz, Miri; Rosand, Jonathan; Sander, Angelle; Satris, Gabriella; Schnyer, David; Seabury, Seth; Sun, Xiaoying; Toga, Arthur; Valadka, Alex; Wang, Kevin; Yuh, Esther; Zafonte, Ross (2021. ) Association of Sex and Age With Mild Traumatic Brain Injury-Related Symptoms: A TRACK-TBI Study.JAMA network open, , 4 (4 ) ,e213046 More Information

McGuire, Jennifer L; Ngwenya, Laura B; McCullumsmith, Robert E (2019. ) Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies.Molecular psychiatry, , 24 (7 ) ,995-1012 More Information

Robinson, David; Pyle, Logan; Foreman, Brandon; Ngwenya, Laura B; Adeoye, Opeolu; Woo, Daniel; Kreitzer, Natalie (2021. ) Antithrombotic regimens and need for critical care interventions among patients with subdural hematomas.The American journal of emergency medicine, , 47 ,6-12 More Information

Kreitzer, Natalie; Ancona, Rachel; McCullumsmith, Cheryl; Kurowski, Brad G; Foreman, Brandon; Ngwenya, Laura B; Adeoye, Opeolu The Effect of Antidepressants on Depression After Traumatic Brain Injury: A Meta-analysis.The Journal of head trauma rehabilitation, , 34 (3 ) ,E47-E54 More Information

Stein, Murray B; Yuh, Esther; Jain, Sonia; Okonkwo, David O; Mac Donald, Christine L; Levin, Harvey; Giacino, Joseph T; Dikmen, Sureyya; Vassar, Mary J; Diaz-Arrastia, Ramon; Robertson, Claudia S; Nelson, Lindsay D; McCrea, Michael; Sun, Xiaoying; Temkin, Nancy; Taylor, Sabrina R; Markowitz, Amy J; Manley, Geoffrey T; Mukherjee, Pratik (2021. ) Smaller Regional Brain Volumes Predict Posttraumatic Stress Disorder at 3 Months After Mild Traumatic Brain Injury.Biological psychiatry. Cognitive neuroscience and neuroimaging, , 6 (3 ) ,352-359 More Information

Lee, Hyunjo; Mizrahi, Moshe A; Hartings, Jed A; Sharma, Sameer; Pahren, Laura; Ngwenya, Laura B; Moseley, Brian D; Privitera, Michael; Tortella, Frank C; Foreman, Brandon (2019. ) Continuous Electroencephalography After Moderate to Severe Traumatic Brain Injury.Critical care medicine, , 47 (4 ) ,574-582 More Information

Agtarap, Stephanie D; Campbell-Sills, Laura; Jain, Sonia; Sun, Xiaoying; Dikmen, Sureyya; Levin, Harvey; McCrea, Michael A; Mukherjee, Pratik; Nelson, Lindsay D; Temkin, Nancy; Yuh, Esther L; Giacino, Joseph T; Manley, Geoffrey T; Stein, Murray B (2021. ) Satisfaction with Life after Mild Traumatic Brain Injury: A TRACK-TBI Study.Journal of neurotrauma, , 38 (5 ) ,546-554 More Information

Foreman, Brandon; Cass, Daryn; Forbes, Jonathan; Ngwenya, Laura B (2019. ) A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury.Journal of visualized experiments : JoVE, , (145 ) , More Information

Brett, Benjamin L; Kramer, Mark D; Whyte, John; McCrea, Michael A; Stein, Murray B; Giacino, Joseph T; Sherer, Mark; Markowitz, Amy J; Manley, Geoffrey T; Nelson, Lindsay D ; Adeoye, Opeolu; Badjatia, Neeraj; Boase, Kim; Barber, Jason; Bodien, Yelena; Bullock, M Ross; Chesnut, Randall; Corrigan, John D; Crawford, Karen; Diaz-Arrastia, Ramon; Dikmen, Sureyya; Duhaime, Ann-Christine; Ellenbogen, Richard; Feeser, V Ramana; Ferguson, Adam R; Foreman, Brandon; Gardner, Raquel; Gaudette, Etienne; Gonzalez, Luis; Gopinath, Shankar; Gullapalli, Rao; Hemphill, J Claude; Hotz, Gillian; Jain, Sonia; Keene, C Dirk; Korley, Frederick K; Kramer, Joel; Kreitzer, Natalie; Levin, Harvey; Lindsell, Chris; Machamer, Joan; Madden, Christopher; Martin, Alastair; McAllister, Thomas; Merchant, Randall; Mukherjee, Pratik; Ngwenya, Laura B; Noel, Florence; Okonkwo, David; Palacios, Eva; Puccio, Ava; Rabinowitz, Miri; Robertson, Claudia; Rosand, Jonathan; Sander, Angelle; Satris, Gabriella; Schnyer, David; Seabury, Seth; Taylor, Sabrina; Temkin, Nancy; Toga, Arthur; Valadka, Alex; Vassar, Mary; Wang, Kevin; Yue, John K; Yuh, Esther; Zafonte, Ross (2021. ) Latent Profile Analysis of Neuropsychiatric Symptoms and Cognitive Function of Adults 2 Weeks After Traumatic Brain Injury: Findings From the TRACK-TBI Study.JAMA network open, , 4 (3 ) ,e213467 More Information

Foreman, Brandon; Ngwenya, Laura B (2019. ) The Sustainability of Applied Intracranial Multimodality Neuromonitoring after Severe Brain Injury.World neurosurgery, , More Information

Casillo, Stephanie M; Venkatesh, Anisha; Muthiah, Nallammai; Agarwal, Nitin; Scott, Teresa; Romani, Rossana; Fernández, Laura L; Aristizabal, Sarita; Ginalis, Elizabeth E; Ozair, Ahmad; Bhat, Vivek; Faruqi, Arjumand; Bajaj, Ankur; Sonkar, Abhinav Arun; Ikeda, Daniel S; Chiocca, E Antonio; Lonser, Russell R; Sutton, Tracy E; McGregor, John M; Rea, Gary L; Schunemann, Victoria A; Ngwenya, Laura B; Marlin, Evan S; Porensky, Paul N; Shaikhouni, Ammar; Huntoon, Kristin; Dornbos, David; Shaw, Andrew B; Powers, Ciarán J; Gluski, Jacob M; Culver, Lauren G; Goodwin, Alyssa M; Ham, Steven; Marupudi, Neena I; Bhat, Dhananjaya I; Berry, Katherine M; Wu, Eva M; Wang, Michael Y (2021. ) Biographies of international women leaders in neurosurgery.Neurosurgical focus, , 50 (3 ) ,E19 More Information

Ngwenya, Laura B; Danzer, Steve C (2018. ) Impact of Traumatic Brain Injury on Neurogenesis.Frontiers in neuroscience, , 12 ,1014 More Information

Nolan, Amber L; Petersen, Cathrine; Iacono, Diego; Mac Donald, Christine L; Mukherjee, Pratik; van der Kouwe, Andre; Jain, Sonia; Stevens, Allison; Diamond, Bram R; Wang, Ruopeng; Markowitz, Amy J; Fischl, Bruce; Perl, Daniel P; Manley, Geoffrey T; Keene, C Dirk; Diaz-Arrastia, Ramon; Edlow, Brian L (2021. ) Tractography-Pathology Correlations in Traumatic Brain Injury: A TRACK-TBI Study.Journal of neurotrauma, , More Information

Yue, John K; Robinson, Caitlin K; Winkler, Ethan A; Upadhyayula, Pavan S; Burke, John F; Pirracchio, Romain; Suen, Catherine G; Deng, Hansen; Ngwenya, Laura B; Dhall, Sanjay S; Manley, Geoffrey T; Tarapore, Phiroz E (2017. ) Circadian variability of the initial Glasgow Coma Scale score in traumatic brain injury patients.Neurobiology of sleep and circadian rhythms, , 2 ,85-93 More Information

Correll, Erika A; Ramser, Benjamin J; Knott, Maxon V; McCullumsmith, Robert E; McGuire, Jennifer L; Ngwenya, Laura B (2021. ) Deficits in pattern separation and dentate gyrus proliferation after rodent lateral fluid percussion injury.IBRO neuroscience reports, , 10 ,31-41 More Information

Okonkwo, David O; Puffer, Ross C; Puccio, Ava M; Yuh, Esther L; Yue, John K; Diaz-Arrastia, Ramon; Korley, Frederick K; Wang, Kevin K W; Sun, Xiaoying; Taylor, Sabrina R; Mukherjee, Pratik; Markowitz, Amy J; Jain, Sonia; Manley, Geoffrey T (2020. ) Point-of-Care Platform Blood Biomarker Testing of Glial Fibrillary Acidic Protein versus S100 Calcium-Binding Protein B for Prediction of Traumatic Brain Injuries: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study.Journal of neurotrauma, , 37 (23 ) ,2460-2467 More Information

Simpkins, Alexis N; Busl, Katharina M; Amorim, Edilberto; Barnett-Tapia, Carolina; Cervenka, Mackenzie C; Dhakar, Monica B; Etherton, Mark R; Fung, Celia; Griggs, Robert; Holloway, Robert G; Kelly, Adam G; Khan, Imad R; Lizarraga, Karlo J; Madagan, Hannah G; Onweni, Chidinma L; Mestre, Humberto; Rabinstein, Alejandro A; Rubinos, Clio; Dionisio-Santos, Dawling A; Youn, Teddy S; Merck, Lisa H; Maciel, Carolina B (2020. ) Proceedings from the Neurotherapeutics Symposium on Neurological Emergencies: Shaping the Future of Neurocritical Care.Neurocritical care, , 33 (3 ) ,636-645 More Information

Evans, Emily; Cook, Nathan E; Iverson, Grant L; Townsend, Elise L; Duhaime, Ann-Christine (2020. ) Monitoring Outcome after Hospital-Presenting Milder Spectrum Pediatric Traumatic Brain Injury Using the Glasgow Outcome Scale-Extended, Pediatric Revision.Journal of neurotrauma, , 37 (14 ) ,1627-1636 More Information

Agtarap, Stephanie; Kramer, Mark D; Campbell-Sills, Laura; Yuh, Esther; Mukherjee, Pratik; Manley, Geoffrey T; McCrea, Michael A; Dikmen, Sureyya; Giacino, Joseph T; Stein, Murray B; Nelson, Lindsay D (2020. ) Invariance of the Bifactor Structure of Mild Traumatic Brain Injury (mTBI) Symptoms on the Rivermead Postconcussion Symptoms Questionnaire Across Time, Demographic Characteristics, and Clinical Groups: A TRACK-TBI Study.Assessment, , 1073191120913941 More Information

Huie, J Russell; Mondello, Stefania; Lindsell, Christopher J; Antiga, Luca; Yuh, Esther L; Zanier, Elisa R; Masson, Serge; Rosario, Bedda L; Ferguson, Adam R (2020. ) Biomarkers for Traumatic Brain Injury: Data Standards and Statistical Considerations.Journal of neurotrauma, , More Information

Nielson, Jessica L; Cooper, Shelly R; Seabury, Seth A; Luciani, Davide; Fabio, Anthony; Temkin, Nancy R; Ferguson, Adam R (2020. ) Statistical Guidelines for Handling Missing Data in Traumatic Brain Injury Clinical Research.Journal of neurotrauma, , More Information

Krishnamoorthy, Vijay; Temkin, Nancy; Barber, Jason; Foreman, Brandon; Komisarow, Jordan; Korley, Fred K; Laskowitz, Daniel T; Mathew, Joseph P; Hernandez, Adrian; Sampson, John; James, Michael L; Bartz, Raquel; Raghunathan, Karthik; Goldstein, Benjamin A; Markowitz, Amy J; Vavilala, Monica S (2021. ) Association of Early Multiple Organ Dysfunction With Clinical and Functional Outcomes Over the Year Following Traumatic Brain Injury: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study.Critical care medicine, , 49 (10 ) ,1769-1778 More Information

Boase, Kim; Machamer, Joan; Temkin, Nancy R; Dikmen, Sureyya; Wilson, Lindsay; Nelson, Lindsay D; Barber, Jason; Bodien, Yelena G; Giacino, Joseph T; Markowitz, Amy J; McCrea, Michael A; Satris, Gabriela; Stein, Murray B; Taylor, Sabrina R; Manley, Geoffrey T (2021. ) Central Curation of Glasgow Outcome Scale-Extended Data: Lessons Learned from TRACK-TBI.Journal of neurotrauma, , 38 (17 ) ,2419-2434 More Information

Yuh, Esther L; Jain, Sonia; Sun, Xiaoying; Pisica, Dana; Harris, Mark H; Taylor, Sabrina R; Markowitz, Amy J; Mukherjee, Pratik; Verheyden, Jan; Giacino, Joseph T; Levin, Harvey S; McCrea, Michael; Stein, Murray B; Temkin, Nancy R; Diaz-Arrastia, Ramon; Robertson, Claudia S; Lingsma, Hester F; Okonkwo, David O; Maas, Andrew I R; Manley, Geoffrey T ; Adeoye, Opeolu; Badjatia, Neeraj; Boase, Kim; Bodien, Yelena; Corrigan, John D; Crawford, Karen; Dikmen, Sureyya; Duhaime, Ann-Christine; Ellenbogen, Richard; Feeser, V Ramana; Ferguson, Adam R; Foreman, Brandon; Gardner, Raquel; Gaudette, Etienne; Gonzalez, Luis; Gopinath, Shankar; Gullapalli, Rao; Hemphill, J Claude; Hotz, Gillian; Keene, C Dirk; Kramer, Joel; Kreitzer, Natalie; Lindsell, Chris; Machamer, Joan; Madden, Christopher; Martin, Alastair; McAllister, Thomas; Merchant, Randall; Nelson, Lindsay; Ngwenya, Laura B; Noel, Florence; Nolan, Amber; Palacios, Eva; Perl, Daniel; Rabinowitz, Miri; Rosand, Jonathan; Sander, Angelle; Satris, Gabriella; Schnyer, David; Seabury, Seth; Toga, Arthur; Valadka, Alex; Vassar, Mary; Zafonte, Ross (2021. ) Pathological Computed Tomography Features Associated With Adverse Outcomes After Mild Traumatic Brain Injury: A TRACK-TBI Study With External Validation in CENTER-TBI.JAMA neurology, , 78 (9 ) ,1137-1148 More Information

McCrea, Michael A; Giacino, Joseph T; Barber, Jason; Temkin, Nancy R; Nelson, Lindsay D; Levin, Harvey S; Dikmen, Sureyya; Stein, Murray; Bodien, Yelena G; Boase, Kim; Taylor, Sabrina R; Vassar, Mary; Mukherjee, Pratik; Robertson, Claudia; Diaz-Arrastia, Ramon; Okonkwo, David O; Markowitz, Amy J; Manley, Geoffrey T ; Adeoye, Opeolu; Badjatia, Neeraj; Bullock, M Ross; Chesnut, Randall; Corrigan, John D; Crawford, Karen; Duhaime, Ann-Christine; Ellenbogen, Richard; Feeser, V Ramana; Ferguson, Adam R; Foreman, Brandon; Gardner, Raquel; Gaudette, Etienne; Goldman, Dana; Gonzalez, Luis; Gopinath, Shankar; Gullapalli, Rao; Hemphill, J Claude; Hotz, Gillian; Jain, Sonia; Keene, C Dirk; Korley, Frederick K; Kramer, Joel; Kreitzer, Natalie; Lindsell, Chris; Machamer, Joan; Madden, Christopher; Martin, Alastair; McAllister, Thomas; Merchant, Randall; Ngwenya, Laura B; Noel, Florence; Nolan, Amber; Palacios, Eva; Perl, Daniel; Puccio, Ava; Rabinowitz, Miri; Rosand, Jonathan; Sander, Angelle; Satris, Gabriella; Schnyer, David; Seabury, Seth; Sherer, Mark; Toga, Arthur; Valadka, Alex; Wang, Kevin; Yue, John K; Yuh, Esther; Zafonte, Ross (2021. ) Functional Outcomes Over the First Year After Moderate to Severe Traumatic Brain Injury in the Prospective, Longitudinal TRACK-TBI Study.JAMA neurology, , 78 (8 ) ,982-992 More Information

Knott, Maxon V; Ngwenya, Laura B; Correll, Erika A; Bohnert, Judy; Ziemba, Noah J; Allgire, Emily; Hopkins, Tracy; McGuire, Jennifer L (2021. ) Lack of Glutamate Receptor Subunit Expression Changes in Hippocampal Dentate Gyrus after Experimental Traumatic Brain Injury in a Rodent Model of Depression.International journal of molecular sciences, , 22 (15 ) , More Information

Williams, John R; Nieblas-Bedolla, Edwin; Feroze, Abdullah; Young, Christopher; Temkin, Nancy R; Giacino, Joseph T; Okonkwo, David O; Manley, Geoffrey T; Barber, Jason; Durfy, Sharon; Markowitz, Amy J; Yuh, Esther L; Mukherjee, Pratik; Mac Donald, Christine L (2021. ) Prognostic Value of Hemorrhagic Brainstem Injury on Early Computed Tomography: A TRACK-TBI Study.Neurocritical care, , More Information

Robinson, David; Kreitzer, Natalie; Ngwenya, Laura B; Adeoye, Opeolu; Woo, Daniel; Hartings, Jed; Foreman, Brandon (2021. ) Diffusion-Weighted Imaging Reveals Distinct Patterns of Cytotoxic Edema in Patients with Subdural Hematomas.Journal of neurotrauma, , More Information

Foreman, Brandon; Lee, Hyunjo; Mizrahi, Moshe A; Hartings, Jed A; Ngwenya, Laura B; Privitera, Michael; Tortella, Frank C; Zhang, Nanhua; Kramer, Joel H (2021. ) Seizures and Cognitive Outcome After Traumatic Brain Injury: A Post Hoc Analysis.Neurocritical care, , More Information

Wright, James; Elder, Theresa; Gerges, Christina; Reisen, Breanne; Wright, Christina; Jella, Tarun; Shah, Sanjit; Yang, George; Ngwenya, Laura B; Wang, Vincent; Parr, Ann M (2021. ) A systematic review of telehealth for the delivery of emergent neurosurgical care.Journal of telemedicine and telecare, , 27 (5 ) ,261-268 More Information

Yue, John K; Phelps, Ryan Rl; Hemmerle, Debra D; Upadhyayula, Pavan S; Winkler, Ethan A; Deng, Hansen; Chang, Diana; Vassar, Mary J; Taylor, Sabrina R; Schnyer, David M; Lingsma, Hester F; Puccio, Ava M; Yuh, Esther L; Mukherjee, Pratik; Huang, Michael C; Ngwenya, Laura B; Valadka, Alex B; Markowitz, Amy J; Okonkwo, David O; Manley, Geoffrey T Predictors of six-month inability to return to work in previously employed subjects after mild traumatic brain injury: A TRACK-TBI pilot study.Journal of concussion, , 5 , More Information

Bodien, Yelena G; Barra, Alice; Temkin, Nancy R; Barber, Jason; Foreman, Brandon; Vassar, Mary; Robertson, Claudia; Taylor, Sabrina R; Markowitz, Amy J; Manley, Geoffrey T; Giacino, Joseph T; Edlow, Brian L (2021. ) Diagnosing Level of Consciousness: The Limits of the Glasgow Coma Scale Total Score.Journal of neurotrauma, , 38 (23 ) ,3295-3305 More Information

Kreitzer, Natalie; Jain, Sonia; Young, Jacob S; Sun, Xiaoying; Stein, Murray B; McCrea, Michael A; Levin, Harvey S; Giacino, Joseph T; Markowitz, Amy J; Manley, Geoffrey T; Nelson, Lindsay D (2021. ) Comparing the Quality of Life after Brain Injury-Overall Scale and Satisfaction with Life Scale as Outcome Measures for Traumatic Brain Injury Research.Journal of neurotrauma, , 38 (23 ) ,3352-3363 More Information

Rincon, Sandra P; Mukherjee, Pratik; Levin, Harvey S; Temkin, Nancy R; Mac Donald, Christine L; Krainak, Daniel M; Sun, Xiaoying; Jain, Sonia; Taylor, Sabrina R; Markowitz, Amy J; Kumar, Allison; Manley, Geoffrey T; Yuh, Esther L (2021. ) Interrater Reliability of National Institutes of Health Traumatic Brain Injury Imaging Common Data Elements for Brain Magnetic Resonance Imaging in Mild Traumatic Brain Injury.Journal of neurotrauma, , 38 (20 ) ,2831-2840 More Information

Machamer, Joan; Temkin, Nancy; Dikmen, Sureyya; Nelson, Lindsay D; Barber, Jason; Hwang, Phillip; Boase, Kim; Stein, Murray B; Sun, Xiaoying; Giacino, Joseph; McCrea, Michael A; Taylor, Sabrina R; Jain, Sonia; Manley, Geoff (2022. ) Symptom Frequency and Persistence in the First Year after Traumatic Brain Injury: A TRACK-TBI Study.Journal of neurotrauma, , 39 (5-6 ) ,358-370 More Information

Foreman, Brandon; Lee, Hyunjo; Okonkwo, David O; Strong, Anthony J; Pahl, Clemens; Shutter, Lori A; Dreier, Jens P; Ngwenya, Laura B; Hartings, Jed A (2022. ) The Relationship Between Seizures and Spreading Depolarizations in Patients with Severe Traumatic Brain Injury.Neurocritical care, , More Information

Galimberti, Stefania; Graziano, Francesca; Maas, Andrew I R; Isernia, Giulia; Lecky, Fiona; Jain, Sonia; Sun, Xiaoying; Gardner, Raquel C; Taylor, Sabrina R; Markowitz, Amy J; Manley, Geoffrey T; Valsecchi, Maria Grazia; Bellelli, Giuseppe; Citerio, Giuseppe (2022. ) Effect of frailty on 6-month outcome after traumatic brain injury: a multicentre cohort study with external validation.The Lancet. Neurology, , 21 (2 ) ,153-162 More Information

Contact Information

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231 Albert Sabin Way
Cincinnati  Ohio, 45267
Phone: 513-558-0434
Laura.Ngwenya@uc.edu