
Laura Benjamin Ngwenya , MD,PhD
Associate Professor of Clinical
Director of Neurotrauma
Medical Sciences Building
231 Albert Sabin Way
Room 5251
Cincinnati, Ohio 45267
Phone 513-558-0434
Email Laura.Ngwenya@uc.edu
Professional Summary
Associate Professor of Neurosurgery
Director of Neurotrauma
Surgical Director, Neurosciences Intensive Care Unit
Education
Bachelor's Degree: Rutgers University
Doctor of Philosophy: Boston University
Medical Degree: Boston University
Neurological Surgery Residency: The Ohio State University
Neurotrauma and Neurocritical Care Fellowship: University of California San Francisco
Certifications
American Board of Neurological Surgery (Certification Date: 11-02-2019 )
Clinical Interests
Neurosurgery
N/A
Stroke
Acute Head Bleeds
Acute Stroke
Arachnoid Cysts
Arnold-Chiari Malformation
Back Injuries
Benign Peripheral Nerve Tumor
Brain Abscess
Brain Concussion
Brain Hemorrhage
Brain Injuries
Carpal Tunnel Syndrome
Cerebral Contusion
Cerebral Hemorrhage
Cerebrovascular Trauma
Cervical Radiculopathy (pinched nerve)
Cervical Spondylosis
Cervicitis
Chiari Malformation
Concussion
Degenerative Spine Disease
Head Injury
Head Trauma
Hemorrhagic Stroke
Herniated Discs
Hydrocephalus
Intervertebral Disc Degeneration
Intervertebral Disc Displacement
Intracerebral Hemorrhage (ICH)
Intracranial Hematoma
Intracranial Hemorrhages
Intraventricular Hemorrhage
Lumbar Radiculopathy
Lumbar Spinal Stenosis
Mild Traumatic Brain Injury
Neck Pain
Neck/Spine Injury
Normal Pressure Hydrocephalus
Peripheral Nerve Disorders
Peripheral Nerve Tumors
Peripheral Nervous System Disease
Pinched Nerve
Pseudotumor Cerebri (Idiopathic Intracranial Hypertension)
Sciatica
Severe Brain Injury
Severe Traumatic Brain Injury
Skull Fractures
Spinal Cord Compression
Spinal Cord Injuries
Spinal Cord Tumor
Spinal Disease
Spinal Disorders
Spinal Fluid Leaks
Spinal Fractures
Spinal Fusion
Spinal Injuries
Spinal Stenosis
Spinal Tumors
Spine Infections
Subarachnoid Hemorrhage
Subdural Hematoma
Temporal Bone Fractures
Thoracic and Lumbar Spine Disorders
Traumatic Brain Injury (TBI)
Traumatic Spine Fractures
Specialities
Neurological Surgery
Research and Practice Interests
Neurotrauma, Traumatic brain injury, Spinal injury, General Neurosurgery
Dr. Ngwenya has a clinical and research interest in neurotrauma, specifically, traumatic brain injury. Her clinical research involves identifying subsets of traumatic brain injured patients for targeted intervention. Her basic science laboratory focuses on alterations in adult neurogenesis, spreading depolarizations, and identifying substrates that underlie cognitive deficits after traumatic brain injury.
Research Support
Grant: #HOPES Investigators:Andaluz, Norberto; Hartings, Jed; Hinzman, Jason; Ngwenya, Laura 05-01-2015 -12-31-2018 Vivian L Smith Foundation for Neurological Research HypOthermia for Patients requiring Evacuation of Subdural Hematoma (HOPES): a Multicenter, Randomized Clinical Trial Role:PI $77,463.89 Active Level:Private Non-Profit
Grant: #2017 Grant Investigators:McGuire, Jennifer; Ngwenya, Laura 09-01-2017 -08-31-2019 Local Initiative for Excellence (L.I.F.E.) Identifying the genetic risk underlying poor cognitive recovery after traumatic brain injury Role:PI $50,000.00 Active Level:Private Non-Profit
Grant: #K08NS110988 Investigators:Ngwenya, Laura 04-15-2019 -01-31-2024 National Institute of Neurological Disorders and Stroke Spreading depolarizations and brain dysfunction following traumatic brain injury Role:PI $201,014.00 Awarded Level:Federal
Grant: #Medical Student Summer Research Fellowship (MSSRF) Investigators:Ngwenya, Laura 06-10-2019 -08-10-2019 Neurosurgery Research and Education Foundation The Effects of Cortical Spreading Depolarizations on the Hippocampus Role:PI $2,500.00 Awarded Level:Private Non-Profit
Grant: #UFRA-141 / Gift Funding / CA-0132058 Investigators:Adeoye, Opeolu; Ngwenya, Laura 09-01-2018 -08-31-2020 University of California, San Francisco TRACK-TBI Imaging, Physiologic, and Molecular Biomarkers of Post-TBI Epileptogenesis in Humans: Toward a CURE (TRACK-TBI CURE) Role:PI $263,000.00 Active Level:Institution of Higher Education
Grant: #10222sc / W81XWH-14-2-0176 Investigators:Adeoye, Opeolu; Ngwenya, Laura 09-30-2016 -09-29-2019 Department of the Army Medical Research Acquisition Activity TBI Endpoints Development (TED) Role:PI $161,200.00 Active Level:Federal
Grant: #W81XWH-20-1-0830 Investigators:Goodman, Michael; Hartings, Jed; McGuire, Jennifer; Ngwenya, Laura 09-01-2020 -08-31-2022 Department of the Army Medical Research Acquisition Activity DM190198 - Rapid Ketone Infusion to Prevent Brain Energy Depletion and Secondary Brain Injury in Severe TBI with Hemorrhagic Shock Role:Collaborator $723,710.00 Awarded Level:Federal
Grant: #RSA 12234sc / NFL A131769 Investigators:Ngwenya, Laura 04-01-2020 -06-30-2021 National Football League Scientific Advisory Board Transforming Research and Clinical Knowledge in Traumatic Brain Injury (Track TBI Longitudinal Study) Role:PI $56,000.00 Awarded Level:Industry
Grant: #CS-2018-0009 / W81XWH-19-C-0071 Investigators:Ngwenya, Laura 07-15-2020 -07-14-2022 Department of the Army Medical Research and Materiel Command Clinical Evaluation of the i-STAT TBI Test (i-STAT Study) Role:PI $82,311.00 Active Level:Federal
Grant: #581679/U01NS114140 Investigators:Ngwenya, Laura 03-15-2020 -02-28-2021 University of Pennsylvania Clinical Validation of Serum Neurofilament Light as a Biomarker of Traumatic Axonal Injury Role:PI 3200.00 Hold Level:Higher Education
Grant: #W81XWH-21-C-0075 Investigators:Foreman, Brandon; Hartings, Jed; Jandarov, Roman; Ngwenya, Laura 09-20-2021 -09-19-2024 Department of the Army Medical Research Acquisition Activity JW200215 - Improving Neurotrauma by Depolarization Inhibition with Combination Therapy (INDICT): a Phase 2 Randomized Trial Role:Collaborator 0.00 Hold Level:Federal
Grant: #578105 / W81XWH-19-1-0861 09-30-2019 -09-29-2020 Department of the Army Medical Research Acquisition Activity TRACK-TBI Epileptogenesis Project Role:PI 0.00 Hold Level:Federal
Grant: #578105 / W81XWH-19-1-0861 09-30-2019 -09-29-2020 Department of the Army Medical Research Acquisition Activity TRACK-TBI Epileptogenesis Project Role:PI 0.00 Hold Level:Federal
Publications
Peer Reviewed Publications
Estrada, Larissa I; Robinson, Amy A; Amaral, Ana C; Giannaris, Eustathia L; Heyworth, Nadine C; Mortazavi, Farzad; Ngwenya, Laura B; Roberts, Debra E; Cabral, Howard J; Killiany, Ronald J; Rosene, Douglas L (2017. ) Evaluation of Long-Term Cryostorage of Brain Tissue Sections for Quantitative Histochemistry.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, , 65 (3 ) ,153-171 More Information
Ngwenya, Laura B; Burke, John F; Manley, Geoffrey T (2016. ) Brain Tissue Oxygen Monitoring and the Intersection of Brain and Lung: A Comprehensive Review.Respiratory care, , 61 (9 ) ,1232-44 More Information
Burke, John Frederick; Yue, John K; Ngwenya, Laura Benjamin; Winkler, Ethan A; Talbott, Jason; Pan, Jonathan; Ferguson, Adam; Beattie, Michael; Bresnahan, Jacqueline; Haefeli, Jenny; Whetstone, William; Suen, Catherine; Huang, Michael C; Manley, Geoffrey T; Tarapore, Phiroz E; Dhall, Sanjay S (2016. ) 182?Ultra-Early (<12 Hours) Decompression Improves Recovery After Spinal Cord Injury Compared to Early (12-24 Hours) Decompression.Neurosurgery, , 63 Suppl 1 ,172 More Information
Ngwenya, Laura B; Prevedello, Luciano M; Youssef, Patrick P (2016. ) Concomitant epidural and subdural spinal abscess: a case report.The spine journal : official journal of the North American Spine Society, , 16 (4 ) ,e275-82 More Information
Ngwenya, Laura B; Heyworth, Nadine C; Shwe, Yamin; Moore, Tara L; Rosene, Douglas L (2015. ) Age-related changes in dentate gyrus cell numbers, neurogenesis, and associations with cognitive impairments in the rhesus monkey.Frontiers in systems neuroscience, , 9 ,102 More Information
Ngwenya, Laura B; Chiocca, E Antonio (2013. ) Editorial: postoperative ischemia.Journal of neurosurgery, , 118 (4 ) ,799-800; discussion More Information
Ngwenya, Laura B; Chiocca, E Antonio Do meningioma patients benefit from antiepileptic drug treatment?.World neurosurgery, , 79 (3-4 ) ,433-4 More Information
Ngwenya, Laura B; Chiocca, E Antonio (2012. ) Editorial: meningioma and radiotherapy.Journal of neurosurgery, , 117 (4 ) ,666-8 More Information
Ngwenya, Laura B; Chiocca, E Antonio Treatment for paragangliomas: passing the test of time.World neurosurgery, , 77 (5-6 ) ,639-41 More Information
Ngwenya, Laura B; Chiocca, E Antonio (2011. ) Extent of resection.Journal of neurosurgery, , 115 (1 ) ,1-2; discussion 2 More Information
Ngwenya, Laura B; Rosene, Douglas L; Peters, Alan (2008. ) An ultrastructural characterization of the newly generated cells in the adult monkey dentate gyrus.Hippocampus, , 18 (2 ) ,210-20 More Information
Ngwenya, Laura B; Peters, Alan; Rosene, Douglas L (2006. ) Maturational sequence of newly generated neurons in the dentate gyrus of the young adult rhesus monkey.The Journal of comparative neurology, , 498 (2 ) ,204-16 More Information
Ngwenya, Laura B; Peters, Alan; Rosene, Douglas L (2005. ) Light and electron microscopic immunohistochemical detection of bromodeoxyuridine-labeled cells in the brain: different fixation and processing protocols.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, , 53 (7 ) ,821-32 More Information
Ngwenya, Laura B; Suen, Catherine G; Tarapore, Phiroz E; Manley, Geoffrey T; Huang, Michael C (2017. ) Safety and cost efficiency of a restrictive transfusion protocol in patients with traumatic brain injury.Journal of neurosurgery, , 1-8 More Information
Yue, John K; Ngwenya, Laura B; Upadhyayula, Pavan S; Deng, Hansen; Winkler, Ethan A; Burke, John F; Lee, Young M; Robinson, Caitlin K; Ferguson, Adam R; Lingsma, Hester F; Cnossen, Maryse C; Pirracchio, Romain; Korley, Frederick K; Vassar, Mary J; Yuh, Esther L; Mukherjee, Pratik; Gordon, Wayne A; Valadka, Alex B; Okonkwo, David O; Manley, Geoffrey T (2017. ) Emergency department blood alcohol level associates with injury factors and six-month outcome after uncomplicated mild traumatic brain injury.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, , More Information
Yue, John K; Burke, John F; Upadhyayula, Pavan S; Winkler, Ethan A; Deng, Hansen; Robinson, Caitlin K; Pirracchio, Romain; Suen, Catherine G; Sharma, Sourabh; Ferguson, Adam R; Ngwenya, Laura B; Stein, Murray B; Manley, Geoffrey T; Tarapore, Phiroz E (2017. ) Selective Serotonin Reuptake Inhibitors for Treating Neurocognitive and Neuropsychiatric Disorders Following Traumatic Brain Injury: An Evaluation of Current Evidence.Brain sciences, , 7 (8 ) , More Information
Martin, Grace E; Carroll, Christopher P; Plummer, Zach J; Millar, D A; Pritts, Timothy A; Makley, Amy T; Joseph, Bellal A; Ngwenya, Laura B; Goodman, Michael D (2017. ) Safety and Efficacy of Brain Injury Guidelines at a Level III Trauma Center.The journal of trauma and acute care surgery, , More Information
Hartings, Jed A; Ngwenya, Laura B; Carroll, Christopher P; Foreman, Brandon (2018. ) Letter to the Editor. Ketamine sedation for the suppression of spreading depolarizations.Journal of neurosurgery, , 1-2 More Information
McGuire, Jennifer L; DePasquale, Erica A K; Watanabe, Miki; Anwar, Fatima; Ngwenya, Laura B; Atluri, Gowtham; Romick-Rosendale, Lindsey E; McCullumsmith, Robert E; Evanson, Nathan K (2018. ) Chronic Dysregulation of Cortical and Subcortical Metabolism After Experimental Traumatic Brain Injury.Molecular neurobiology, , More Information
Foreman, Brandon; Ngwenya, Laura B; Stoddard, Erica; Hinzman, Jason M; Andaluz, Norberto; Hartings, Jed A (2018. ) Safety and Reliability of Bedside, Single Burr Hole Technique for Intracranial Multimodality Monitoring in Severe Traumatic Brain Injury.Neurocritical care, , More Information
Hartings, Jed A; Ngwenya, Laura B; Watanabe, Tomas; Foreman, Brandon (2018. ) Commentary: Detecting Cortical Spreading Depolarization with Full Band Scalp Electroencephalography: An Illusion?.Frontiers in systems neuroscience, , 12 ,19 More Information
Ngwenya, Laura B; Mazumder, Sarmistha; Porter, Zachary R; Minnema, Amy; Oswald, Duane J; Farhadi, H Francis (2018. ) Implantation of Neuronal Stem Cells Enhances Object Recognition without Increasing Neurogenesis after Lateral Fluid Percussion Injury in Mice.Stem cells international, , 2018 ,4209821 More Information
Ngwenya, Laura B; Gardner, Raquel C; Yue, John K; Burke, John F; Ferguson, Adam R; Huang, Michael C; Winkler, Ethan A; Pirracchio, Romain; Satris, Gabriela G; Yuh, Esther L; Mukherjee, Pratik; Valadka, Alex B; Okonkwo, David O; Manley, Geoffrey T (2018. ) Concordance of common data elements for assessment of subjective cognitive complaints after mild-traumatic brain injury: a TRACK-TBI Pilot Study.Brain injury, , 32 (9 ) ,1071-1078 More Information
Wright, James M; Gerges, Christina; Shammassian, Berje; Labak, Collin M; Herring, Eric Z; Miller, Benjamin; Alkhachroum, Ayham; Kottapally, Mohan; Huang Wright, Christina; Rodgers, Richard B; Sedney, Cara; Ngwenya, Laura B; Stippler, Martina; Sieg, Emily; Babu, Maya A; Hoffer, Alan; Hejal, Rana (2021. ) Prone Position Ventilation in Neurologically Ill Patients: A Systematic Review and Proposed Protocol.Critical care medicine, , More Information
Robinson, David; Pyle, Logan; Foreman, Brandon; Ngwenya, Laura B; Adeoye, Opeolu; Woo, Daniel; Kreitzer, Natalie (2020. ) Factors Associated with Early versus Delayed Expansion of Acute Subdural Hematomas Initially Managed Conservatively.Journal of neurotrauma, , More Information
Matur, Abhijith V; Ngwenya, Laura B; Prestigiacomo, Charles J (2020. ) The surgical history of head injury in motor vehicle collision.Journal of neurosurgery, , 1-7 More Information
Barhorst, Kinsey A; Alfawares, Yara; McGuire, Jennifer L; Danzer, Steve C; Hartings, Jed A; Ngwenya, Laura B (2020. ) Remote and Persistent Alterations in Glutamate Receptor Subunit Composition Induced by Spreading Depolarizations in Rat Brain.Cellular and molecular neurobiology, , More Information
Shah, Sanjit; Yang, George L; Le, Diana T; Gerges, Christina; Wright, James M; Parr, Ann M; Cheng, Joseph S; Ngwenya, Laura B (2020. ) Examining the Emergency Medical Treatment and Active Labor Act: impact on telemedicine for neurotrauma.Neurosurgical focus, , 49 (5 ) ,E8 More Information
Le, Diana T; Barhorst, Kinsey A; Castiglione, James; Yang, George L; Shah, Sanjit J; Harlan, Sarah S; Keegan, Shaun P; Jandarov, Roman A; Ngwenya, Laura B; Prestigiacomo, Charles J (2020. ) Blunt cerebrovascular injury in the geriatric population.Neurosurgical focus, , 49 (4 ) ,E10 More Information
Rath, Kelly; Kreitzer, Natalie; Schlichter, Erika; Lopez, Omar; Ferioli, Simona; Ngwenya, Laura B; Foreman, Brandon (2020. ) The Experience of a Neurocritical Care Admission and Discharge for Patients and Their Families: A Qualitative Analysis.The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, , 52 (4 ) ,179-185 More Information
Rhame, Katherine; Le, Diana; Ventura, Amanda; Horner, Amy; Andaluz, Norberto; Miller, Christopher; Stolz, Uwe; Ngwenya, Laura B; Adeoye, Opeolu; Kreitzer, Natalie (2020. ) Management of the mild traumatic brain injured patient using a multidisciplinary observation unit protocol.The American journal of emergency medicine, , More Information
Porter, Zachary R; Mejia-Munne, Juan C; Krueger, Bryan M; Kosty, Jennifer A; Ngwenya, Laura B (2020. ) Sacral Rheumatoid Nodule: An Unusual Indication for Coccygectomy.Case reports in surgery, , 2020 ,2757625 More Information
Kreitzer, Natalie; Bakas, Tamilyn; Kurowski, Brad; Lindsell, Christopher J; Ferioli, Simona; Foreman, Brandon; Ngwenya, Laura B; Thomas, Stephanie; Keegan, Sara; Adeoye, Opeolu The Experience of Caregivers Following a Moderate to Severe Traumatic Brain Injury Requiring ICU Admission.The Journal of head trauma rehabilitation, , 35 (3 ) ,E299-E309 More Information
Rhame, Katherine; Le, Diana; Horner, Amy; Thomas, Andrea; Foreman, Brandon P; Kreitzer, Natalie P; Ngwenya, Laura B (2020. ) Implementation of a Neurotrauma Hotline for post-hospital continuity of care.Acta neurologica Scandinavica, , 141 (4 ) ,351-354 More Information
Hartings, Jed A; Andaluz, Norberto; Bullock, M Ross; Hinzman, Jason M; Mathern, Bruce; Pahl, Clemens; Puccio, Ava; Shutter, Lori A; Strong, Anthony J; Vagal, Achala; Wilson, J Adam; Dreier, Jens P; Ngwenya, Laura B; Foreman, Brandon; Pahren, Laura; Lingsma, Hester; Okonkwo, David O (2020. ) Prognostic Value of Spreading Depolarizations in Patients With Severe Traumatic Brain Injury.JAMA neurology, , 77 (4 ) ,489-499 More Information
Ngwenya, Laura B (2020. ) Commentary: Concussion Guidelines Step 2: Evidence for Subtype Classification.Neurosurgery, , 86 (1 ) ,E1 More Information
McGuire, Jennifer L; Correll, Erika A; Lowery, Alexandra C; Rhame, Katherine; Anwar, Fatima N; McCullumsmith, Robert E; Ngwenya, Laura B (2019. ) Pioglitazone improves working memory performance when administered in chronic TBI.Neurobiology of disease, , 132 ,104611 More Information
Dossani, Rimal H; Terrell, Danielle; Kosty, Jennifer A; Ross, Robert C; Demand, Audrey; Wild, Elizabeth; Peterson, Racheal; Ngwenya, Laura B; Benzil, Deborah L; Notarianni, Christina (2019. ) Gender disparities in academic rank achievement in neurosurgery: a critical assessment.Journal of neurosurgery, , 1-6 More Information
Khalid, Fatima; Yang, George L; McGuire, Jennifer L; Robson, Matthew J; Foreman, Brandon; Ngwenya, Laura B; Lorenz, John N (2019. ) Autonomic dysfunction following traumatic brain injury: translational insights.Neurosurgical focus, , 47 (5 ) ,E8 More Information
Robinson, Michael W; Prestigiacomo, Charles J; Ngwenya, Laura B (2021. ) Commentary: Intracerebral Hemorrhage Volume Reduction and Timing of Intervention Versus Functional Benefit and Survival in the MISTIE III and STICH Trials.Neurosurgery, , 88 (5 ) ,E394-E395 More Information
Burke, John F; Yue, John K; Ngwenya, Laura B; Winkler, Ethan A; Talbott, Jason F; Pan, Jonathan Z; Ferguson, Adam R; Beattie, Michael S; Bresnahan, Jacqueline C; Haefeli, Jenny; Whetstone, William D; Suen, Catherine G; Huang, Michael C; Manley, Geoffrey T; Tarapore, Phiroz E; Dhall, Sanjay S (2019. ) In Reply: Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury.Neurosurgery, , 85 (2 ) ,E401-E402 More Information
Xu, Linda B; Yue, John K; Korley, Frederick; Puccio, Ava M; Yuh, Esther L; Sun, Xiaoying; Rabinowitz, Miri; Vassar, Mary J; Taylor, Sabrina R; Winkler, Ethan A; Puffer, Ross C; Deng, Hansen; McCrea, Michael; Stein, Murray B; Robertson, Claudia S; Levin, Harvey S; Dikmen, Sureyya; Temkin, Nancy R; Giacino, Joseph T; Mukherjee, Pratik; Wang, Kevin K W; Okonkwo, David O; Markowitz, Amy J; Jain, Sonia; Manley, Geoffrey T; Diaz-Arrastia, Ramon (2021. ) High-Sensitivity C-Reactive Protein is a Prognostic Biomarker of Six-Month Disability after Traumatic Brain Injury: Results from the TRACK-TBI Study.Journal of neurotrauma, , 38 (7 ) ,918-927 More Information
Burke, John F; Yue, John K; Ngwenya, Laura B; Winkler, Ethan A; Talbott, Jason F; Pan, Jonathan Z; Ferguson, Adam R; Beattie, Michael S; Bresnahan, Jacqueline C; Haefeli, Jenny; Whetstone, William D; Suen, Catherine G; Huang, Michael C; Manley, Geoffrey T; Tarapore, Phiroz E; Dhall, Sanjay S (2019. ) Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury.Neurosurgery, , 85 (2 ) ,199-203 More Information
Levin, Harvey S; Temkin, Nancy R; Barber, Jason; Nelson, Lindsay D; Robertson, Claudia; Brennan, Jeffrey; Stein, Murray B; Yue, John K; Giacino, Joseph T; McCrea, Michael A; Diaz-Arrastia, Ramon; Mukherjee, Pratik; Okonkwo, David O; Boase, Kim; Markowitz, Amy J; Bodien, Yelena; Taylor, Sabrina; Vassar, Mary J; Manley, Geoffrey T ; Adeoye, Opeolu; Badjatia, Neeraj; Bullock, M Ross; Chesnut, Randall; Corrigan, John D; Crawford, Karen; Dikmen, Sureyya; Duhaime, Ann-Christine; Ellenbogen, Richard; Feeser, V Ramana; Ferguson, Adam R; Foreman, Brandon; Gardner, Raquel; Gaudette, Etienne; Gonzalez, Luis; Gopinath, Shankar; Gullapalli, Rao; Hemphill, J Claude; Hotz, Gillian; Jain, Sonia; Keene, C Dirk; Korley, Frederick K; Kramer, Joel; Kreitzer, Natalie; Lindsell, Chris; Machamer, Joan; Madden, Christopher; Martin, Alastair; McAllister, Thomas; Merchant, Randall; Nolan, Amber; Ngwenya, Laura B; Noel, Florence; Palacios, Eva; Puccio, Ava; Rabinowitz, Miri; Rosand, Jonathan; Sander, Angelle; Satris, Gabriella; Schnyer, David; Seabury, Seth; Sun, Xiaoying; Toga, Arthur; Valadka, Alex; Wang, Kevin; Yuh, Esther; Zafonte, Ross (2021. ) Association of Sex and Age With Mild Traumatic Brain Injury-Related Symptoms: A TRACK-TBI Study.JAMA network open, , 4 (4 ) ,e213046 More Information
McGuire, Jennifer L; Ngwenya, Laura B; McCullumsmith, Robert E (2019. ) Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies.Molecular psychiatry, , 24 (7 ) ,995-1012 More Information
Robinson, David; Pyle, Logan; Foreman, Brandon; Ngwenya, Laura B; Adeoye, Opeolu; Woo, Daniel; Kreitzer, Natalie (2021. ) Antithrombotic regimens and need for critical care interventions among patients with subdural hematomas.The American journal of emergency medicine, , 47 ,6-12 More Information
Kreitzer, Natalie; Ancona, Rachel; McCullumsmith, Cheryl; Kurowski, Brad G; Foreman, Brandon; Ngwenya, Laura B; Adeoye, Opeolu The Effect of Antidepressants on Depression After Traumatic Brain Injury: A Meta-analysis.The Journal of head trauma rehabilitation, , 34 (3 ) ,E47-E54 More Information
Stein, Murray B; Yuh, Esther; Jain, Sonia; Okonkwo, David O; Mac Donald, Christine L; Levin, Harvey; Giacino, Joseph T; Dikmen, Sureyya; Vassar, Mary J; Diaz-Arrastia, Ramon; Robertson, Claudia S; Nelson, Lindsay D; McCrea, Michael; Sun, Xiaoying; Temkin, Nancy; Taylor, Sabrina R; Markowitz, Amy J; Manley, Geoffrey T; Mukherjee, Pratik (2021. ) Smaller Regional Brain Volumes Predict Posttraumatic Stress Disorder at 3 Months After Mild Traumatic Brain Injury.Biological psychiatry. Cognitive neuroscience and neuroimaging, , 6 (3 ) ,352-359 More Information
Lee, Hyunjo; Mizrahi, Moshe A; Hartings, Jed A; Sharma, Sameer; Pahren, Laura; Ngwenya, Laura B; Moseley, Brian D; Privitera, Michael; Tortella, Frank C; Foreman, Brandon (2019. ) Continuous Electroencephalography After Moderate to Severe Traumatic Brain Injury.Critical care medicine, , 47 (4 ) ,574-582 More Information
Agtarap, Stephanie D; Campbell-Sills, Laura; Jain, Sonia; Sun, Xiaoying; Dikmen, Sureyya; Levin, Harvey; McCrea, Michael A; Mukherjee, Pratik; Nelson, Lindsay D; Temkin, Nancy; Yuh, Esther L; Giacino, Joseph T; Manley, Geoffrey T; Stein, Murray B (2021. ) Satisfaction with Life after Mild Traumatic Brain Injury: A TRACK-TBI Study.Journal of neurotrauma, , 38 (5 ) ,546-554 More Information
Foreman, Brandon; Cass, Daryn; Forbes, Jonathan; Ngwenya, Laura B (2019. ) A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury.Journal of visualized experiments : JoVE, , (145 ) , More Information
Brett, Benjamin L; Kramer, Mark D; Whyte, John; McCrea, Michael A; Stein, Murray B; Giacino, Joseph T; Sherer, Mark; Markowitz, Amy J; Manley, Geoffrey T; Nelson, Lindsay D ; Adeoye, Opeolu; Badjatia, Neeraj; Boase, Kim; Barber, Jason; Bodien, Yelena; Bullock, M Ross; Chesnut, Randall; Corrigan, John D; Crawford, Karen; Diaz-Arrastia, Ramon; Dikmen, Sureyya; Duhaime, Ann-Christine; Ellenbogen, Richard; Feeser, V Ramana; Ferguson, Adam R; Foreman, Brandon; Gardner, Raquel; Gaudette, Etienne; Gonzalez, Luis; Gopinath, Shankar; Gullapalli, Rao; Hemphill, J Claude; Hotz, Gillian; Jain, Sonia; Keene, C Dirk; Korley, Frederick K; Kramer, Joel; Kreitzer, Natalie; Levin, Harvey; Lindsell, Chris; Machamer, Joan; Madden, Christopher; Martin, Alastair; McAllister, Thomas; Merchant, Randall; Mukherjee, Pratik; Ngwenya, Laura B; Noel, Florence; Okonkwo, David; Palacios, Eva; Puccio, Ava; Rabinowitz, Miri; Robertson, Claudia; Rosand, Jonathan; Sander, Angelle; Satris, Gabriella; Schnyer, David; Seabury, Seth; Taylor, Sabrina; Temkin, Nancy; Toga, Arthur; Valadka, Alex; Vassar, Mary; Wang, Kevin; Yue, John K; Yuh, Esther; Zafonte, Ross (2021. ) Latent Profile Analysis of Neuropsychiatric Symptoms and Cognitive Function of Adults 2 Weeks After Traumatic Brain Injury: Findings From the TRACK-TBI Study.JAMA network open, , 4 (3 ) ,e213467 More Information
Foreman, Brandon; Ngwenya, Laura B (2019. ) The Sustainability of Applied Intracranial Multimodality Neuromonitoring after Severe Brain Injury.World neurosurgery, , More Information
Casillo, Stephanie M; Venkatesh, Anisha; Muthiah, Nallammai; Agarwal, Nitin; Scott, Teresa; Romani, Rossana; Fernández, Laura L; Aristizabal, Sarita; Ginalis, Elizabeth E; Ozair, Ahmad; Bhat, Vivek; Faruqi, Arjumand; Bajaj, Ankur; Sonkar, Abhinav Arun; Ikeda, Daniel S; Chiocca, E Antonio; Lonser, Russell R; Sutton, Tracy E; McGregor, John M; Rea, Gary L; Schunemann, Victoria A; Ngwenya, Laura B; Marlin, Evan S; Porensky, Paul N; Shaikhouni, Ammar; Huntoon, Kristin; Dornbos, David; Shaw, Andrew B; Powers, Ciarán J; Gluski, Jacob M; Culver, Lauren G; Goodwin, Alyssa M; Ham, Steven; Marupudi, Neena I; Bhat, Dhananjaya I; Berry, Katherine M; Wu, Eva M; Wang, Michael Y (2021. ) Biographies of international women leaders in neurosurgery.Neurosurgical focus, , 50 (3 ) ,E19 More Information
Ngwenya, Laura B; Danzer, Steve C (2018. ) Impact of Traumatic Brain Injury on Neurogenesis.Frontiers in neuroscience, , 12 ,1014 More Information
Nolan, Amber L; Petersen, Cathrine; Iacono, Diego; Mac Donald, Christine L; Mukherjee, Pratik; van der Kouwe, Andre; Jain, Sonia; Stevens, Allison; Diamond, Bram R; Wang, Ruopeng; Markowitz, Amy J; Fischl, Bruce; Perl, Daniel P; Manley, Geoffrey T; Keene, C Dirk; Diaz-Arrastia, Ramon; Edlow, Brian L (2021. ) Tractography-Pathology Correlations in Traumatic Brain Injury: A TRACK-TBI Study.Journal of neurotrauma, , More Information
Yue, John K; Robinson, Caitlin K; Winkler, Ethan A; Upadhyayula, Pavan S; Burke, John F; Pirracchio, Romain; Suen, Catherine G; Deng, Hansen; Ngwenya, Laura B; Dhall, Sanjay S; Manley, Geoffrey T; Tarapore, Phiroz E (2017. ) Circadian variability of the initial Glasgow Coma Scale score in traumatic brain injury patients.Neurobiology of sleep and circadian rhythms, , 2 ,85-93 More Information
Correll, Erika A; Ramser, Benjamin J; Knott, Maxon V; McCullumsmith, Robert E; McGuire, Jennifer L; Ngwenya, Laura B (2021. ) Deficits in pattern separation and dentate gyrus proliferation after rodent lateral fluid percussion injury.IBRO neuroscience reports, , 10 ,31-41 More Information
Okonkwo, David O; Puffer, Ross C; Puccio, Ava M; Yuh, Esther L; Yue, John K; Diaz-Arrastia, Ramon; Korley, Frederick K; Wang, Kevin K W; Sun, Xiaoying; Taylor, Sabrina R; Mukherjee, Pratik; Markowitz, Amy J; Jain, Sonia; Manley, Geoffrey T (2020. ) Point-of-Care Platform Blood Biomarker Testing of Glial Fibrillary Acidic Protein versus S100 Calcium-Binding Protein B for Prediction of Traumatic Brain Injuries: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study.Journal of neurotrauma, , 37 (23 ) ,2460-2467 More Information
Simpkins, Alexis N; Busl, Katharina M; Amorim, Edilberto; Barnett-Tapia, Carolina; Cervenka, Mackenzie C; Dhakar, Monica B; Etherton, Mark R; Fung, Celia; Griggs, Robert; Holloway, Robert G; Kelly, Adam G; Khan, Imad R; Lizarraga, Karlo J; Madagan, Hannah G; Onweni, Chidinma L; Mestre, Humberto; Rabinstein, Alejandro A; Rubinos, Clio; Dionisio-Santos, Dawling A; Youn, Teddy S; Merck, Lisa H; Maciel, Carolina B (2020. ) Proceedings from the Neurotherapeutics Symposium on Neurological Emergencies: Shaping the Future of Neurocritical Care.Neurocritical care, , 33 (3 ) ,636-645 More Information
Evans, Emily; Cook, Nathan E; Iverson, Grant L; Townsend, Elise L; Duhaime, Ann-Christine (2020. ) Monitoring Outcome after Hospital-Presenting Milder Spectrum Pediatric Traumatic Brain Injury Using the Glasgow Outcome Scale-Extended, Pediatric Revision.Journal of neurotrauma, , 37 (14 ) ,1627-1636 More Information
Agtarap, Stephanie; Kramer, Mark D; Campbell-Sills, Laura; Yuh, Esther; Mukherjee, Pratik; Manley, Geoffrey T; McCrea, Michael A; Dikmen, Sureyya; Giacino, Joseph T; Stein, Murray B; Nelson, Lindsay D (2020. ) Invariance of the Bifactor Structure of Mild Traumatic Brain Injury (mTBI) Symptoms on the Rivermead Postconcussion Symptoms Questionnaire Across Time, Demographic Characteristics, and Clinical Groups: A TRACK-TBI Study.Assessment, , 1073191120913941 More Information
Huie, J Russell; Mondello, Stefania; Lindsell, Christopher J; Antiga, Luca; Yuh, Esther L; Zanier, Elisa R; Masson, Serge; Rosario, Bedda L; Ferguson, Adam R (2020. ) Biomarkers for Traumatic Brain Injury: Data Standards and Statistical Considerations.Journal of neurotrauma, , More Information
Nielson, Jessica L; Cooper, Shelly R; Seabury, Seth A; Luciani, Davide; Fabio, Anthony; Temkin, Nancy R; Ferguson, Adam R (2020. ) Statistical Guidelines for Handling Missing Data in Traumatic Brain Injury Clinical Research.Journal of neurotrauma, , More Information
Krishnamoorthy, Vijay; Temkin, Nancy; Barber, Jason; Foreman, Brandon; Komisarow, Jordan; Korley, Fred K; Laskowitz, Daniel T; Mathew, Joseph P; Hernandez, Adrian; Sampson, John; James, Michael L; Bartz, Raquel; Raghunathan, Karthik; Goldstein, Benjamin A; Markowitz, Amy J; Vavilala, Monica S (2021. ) Association of Early Multiple Organ Dysfunction With Clinical and Functional Outcomes Over the Year Following Traumatic Brain Injury: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study.Critical care medicine, , 49 (10 ) ,1769-1778 More Information
Boase, Kim; Machamer, Joan; Temkin, Nancy R; Dikmen, Sureyya; Wilson, Lindsay; Nelson, Lindsay D; Barber, Jason; Bodien, Yelena G; Giacino, Joseph T; Markowitz, Amy J; McCrea, Michael A; Satris, Gabriela; Stein, Murray B; Taylor, Sabrina R; Manley, Geoffrey T (2021. ) Central Curation of Glasgow Outcome Scale-Extended Data: Lessons Learned from TRACK-TBI.Journal of neurotrauma, , 38 (17 ) ,2419-2434 More Information
Yuh, Esther L; Jain, Sonia; Sun, Xiaoying; Pisica, Dana; Harris, Mark H; Taylor, Sabrina R; Markowitz, Amy J; Mukherjee, Pratik; Verheyden, Jan; Giacino, Joseph T; Levin, Harvey S; McCrea, Michael; Stein, Murray B; Temkin, Nancy R; Diaz-Arrastia, Ramon; Robertson, Claudia S; Lingsma, Hester F; Okonkwo, David O; Maas, Andrew I R; Manley, Geoffrey T ; Adeoye, Opeolu; Badjatia, Neeraj; Boase, Kim; Bodien, Yelena; Corrigan, John D; Crawford, Karen; Dikmen, Sureyya; Duhaime, Ann-Christine; Ellenbogen, Richard; Feeser, V Ramana; Ferguson, Adam R; Foreman, Brandon; Gardner, Raquel; Gaudette, Etienne; Gonzalez, Luis; Gopinath, Shankar; Gullapalli, Rao; Hemphill, J Claude; Hotz, Gillian; Keene, C Dirk; Kramer, Joel; Kreitzer, Natalie; Lindsell, Chris; Machamer, Joan; Madden, Christopher; Martin, Alastair; McAllister, Thomas; Merchant, Randall; Nelson, Lindsay; Ngwenya, Laura B; Noel, Florence; Nolan, Amber; Palacios, Eva; Perl, Daniel; Rabinowitz, Miri; Rosand, Jonathan; Sander, Angelle; Satris, Gabriella; Schnyer, David; Seabury, Seth; Toga, Arthur; Valadka, Alex; Vassar, Mary; Zafonte, Ross (2021. ) Pathological Computed Tomography Features Associated With Adverse Outcomes After Mild Traumatic Brain Injury: A TRACK-TBI Study With External Validation in CENTER-TBI.JAMA neurology, , 78 (9 ) ,1137-1148 More Information
McCrea, Michael A; Giacino, Joseph T; Barber, Jason; Temkin, Nancy R; Nelson, Lindsay D; Levin, Harvey S; Dikmen, Sureyya; Stein, Murray; Bodien, Yelena G; Boase, Kim; Taylor, Sabrina R; Vassar, Mary; Mukherjee, Pratik; Robertson, Claudia; Diaz-Arrastia, Ramon; Okonkwo, David O; Markowitz, Amy J; Manley, Geoffrey T ; Adeoye, Opeolu; Badjatia, Neeraj; Bullock, M Ross; Chesnut, Randall; Corrigan, John D; Crawford, Karen; Duhaime, Ann-Christine; Ellenbogen, Richard; Feeser, V Ramana; Ferguson, Adam R; Foreman, Brandon; Gardner, Raquel; Gaudette, Etienne; Goldman, Dana; Gonzalez, Luis; Gopinath, Shankar; Gullapalli, Rao; Hemphill, J Claude; Hotz, Gillian; Jain, Sonia; Keene, C Dirk; Korley, Frederick K; Kramer, Joel; Kreitzer, Natalie; Lindsell, Chris; Machamer, Joan; Madden, Christopher; Martin, Alastair; McAllister, Thomas; Merchant, Randall; Ngwenya, Laura B; Noel, Florence; Nolan, Amber; Palacios, Eva; Perl, Daniel; Puccio, Ava; Rabinowitz, Miri; Rosand, Jonathan; Sander, Angelle; Satris, Gabriella; Schnyer, David; Seabury, Seth; Sherer, Mark; Toga, Arthur; Valadka, Alex; Wang, Kevin; Yue, John K; Yuh, Esther; Zafonte, Ross (2021. ) Functional Outcomes Over the First Year After Moderate to Severe Traumatic Brain Injury in the Prospective, Longitudinal TRACK-TBI Study.JAMA neurology, , 78 (8 ) ,982-992 More Information
Knott, Maxon V; Ngwenya, Laura B; Correll, Erika A; Bohnert, Judy; Ziemba, Noah J; Allgire, Emily; Hopkins, Tracy; McGuire, Jennifer L (2021. ) Lack of Glutamate Receptor Subunit Expression Changes in Hippocampal Dentate Gyrus after Experimental Traumatic Brain Injury in a Rodent Model of Depression.International journal of molecular sciences, , 22 (15 ) , More Information
Williams, John R; Nieblas-Bedolla, Edwin; Feroze, Abdullah; Young, Christopher; Temkin, Nancy R; Giacino, Joseph T; Okonkwo, David O; Manley, Geoffrey T; Barber, Jason; Durfy, Sharon; Markowitz, Amy J; Yuh, Esther L; Mukherjee, Pratik; Mac Donald, Christine L (2021. ) Prognostic Value of Hemorrhagic Brainstem Injury on Early Computed Tomography: A TRACK-TBI Study.Neurocritical care, , More Information
Robinson, David; Kreitzer, Natalie; Ngwenya, Laura B; Adeoye, Opeolu; Woo, Daniel; Hartings, Jed; Foreman, Brandon (2021. ) Diffusion-Weighted Imaging Reveals Distinct Patterns of Cytotoxic Edema in Patients with Subdural Hematomas.Journal of neurotrauma, , More Information
Foreman, Brandon; Lee, Hyunjo; Mizrahi, Moshe A; Hartings, Jed A; Ngwenya, Laura B; Privitera, Michael; Tortella, Frank C; Zhang, Nanhua; Kramer, Joel H (2021. ) Seizures and Cognitive Outcome After Traumatic Brain Injury: A Post Hoc Analysis.Neurocritical care, , More Information
Wright, James; Elder, Theresa; Gerges, Christina; Reisen, Breanne; Wright, Christina; Jella, Tarun; Shah, Sanjit; Yang, George; Ngwenya, Laura B; Wang, Vincent; Parr, Ann M (2021. ) A systematic review of telehealth for the delivery of emergent neurosurgical care.Journal of telemedicine and telecare, , 27 (5 ) ,261-268 More Information
Yue, John K; Phelps, Ryan Rl; Hemmerle, Debra D; Upadhyayula, Pavan S; Winkler, Ethan A; Deng, Hansen; Chang, Diana; Vassar, Mary J; Taylor, Sabrina R; Schnyer, David M; Lingsma, Hester F; Puccio, Ava M; Yuh, Esther L; Mukherjee, Pratik; Huang, Michael C; Ngwenya, Laura B; Valadka, Alex B; Markowitz, Amy J; Okonkwo, David O; Manley, Geoffrey T Predictors of six-month inability to return to work in previously employed subjects after mild traumatic brain injury: A TRACK-TBI pilot study.Journal of concussion, , 5 , More Information
Bodien, Yelena G; Barra, Alice; Temkin, Nancy R; Barber, Jason; Foreman, Brandon; Vassar, Mary; Robertson, Claudia; Taylor, Sabrina R; Markowitz, Amy J; Manley, Geoffrey T; Giacino, Joseph T; Edlow, Brian L (2021. ) Diagnosing Level of Consciousness: The Limits of the Glasgow Coma Scale Total Score.Journal of neurotrauma, , 38 (23 ) ,3295-3305 More Information
Kreitzer, Natalie; Jain, Sonia; Young, Jacob S; Sun, Xiaoying; Stein, Murray B; McCrea, Michael A; Levin, Harvey S; Giacino, Joseph T; Markowitz, Amy J; Manley, Geoffrey T; Nelson, Lindsay D (2021. ) Comparing the Quality of Life after Brain Injury-Overall Scale and Satisfaction with Life Scale as Outcome Measures for Traumatic Brain Injury Research.Journal of neurotrauma, , 38 (23 ) ,3352-3363 More Information
Rincon, Sandra P; Mukherjee, Pratik; Levin, Harvey S; Temkin, Nancy R; Mac Donald, Christine L; Krainak, Daniel M; Sun, Xiaoying; Jain, Sonia; Taylor, Sabrina R; Markowitz, Amy J; Kumar, Allison; Manley, Geoffrey T; Yuh, Esther L (2021. ) Interrater Reliability of National Institutes of Health Traumatic Brain Injury Imaging Common Data Elements for Brain Magnetic Resonance Imaging in Mild Traumatic Brain Injury.Journal of neurotrauma, , 38 (20 ) ,2831-2840 More Information
Machamer, Joan; Temkin, Nancy; Dikmen, Sureyya; Nelson, Lindsay D; Barber, Jason; Hwang, Phillip; Boase, Kim; Stein, Murray B; Sun, Xiaoying; Giacino, Joseph; McCrea, Michael A; Taylor, Sabrina R; Jain, Sonia; Manley, Geoff (2022. ) Symptom Frequency and Persistence in the First Year after Traumatic Brain Injury: A TRACK-TBI Study.Journal of neurotrauma, , 39 (5-6 ) ,358-370 More Information
Foreman, Brandon; Lee, Hyunjo; Okonkwo, David O; Strong, Anthony J; Pahl, Clemens; Shutter, Lori A; Dreier, Jens P; Ngwenya, Laura B; Hartings, Jed A (2022. ) The Relationship Between Seizures and Spreading Depolarizations in Patients with Severe Traumatic Brain Injury.Neurocritical care, , More Information
Galimberti, Stefania; Graziano, Francesca; Maas, Andrew I R; Isernia, Giulia; Lecky, Fiona; Jain, Sonia; Sun, Xiaoying; Gardner, Raquel C; Taylor, Sabrina R; Markowitz, Amy J; Manley, Geoffrey T; Valsecchi, Maria Grazia; Bellelli, Giuseppe; Citerio, Giuseppe (2022. ) Effect of frailty on 6-month outcome after traumatic brain injury: a multicentre cohort study with external validation.The Lancet. Neurology, , 21 (2 ) ,153-162 More Information
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Ohio, 45267
Phone: 513-558-0434
Laura.Ngwenya@uc.edu