Yoonjee Park

Yoonjee Park

Assoc Professor

Education

PhD. : Purdue University West Lafayette, Ind., 2010 (Chemical Engineering)

Master of Science: Purdue University West Lafayette, Ind., 2009 (Chemical Engineering)

Bachelor of Science: Seoul National University Seoul, Korea, 2006 (Chemical & Biological Engineering (with Honor))

Positions and Work Experience

2017 -2022 Assistant Professor, Department of Chemical & Environmental Engineering Secondary Appointment: Department of Biomedical Engineering Department of Ophthalmology, University of Cincinnati, Cincinnati, Ohio

2015 -2017 Assistant Professor, Department of Biomedical, Chemical, & Environmental Engineering, University of Cincinnati Secondary Appointment: Biomedical Engineering Program, University of Cincinnati, Cincinnati, Ohio

2014 - Postdoctoral Research Associate, Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Mass.

2010 -2013 Postdoctoral Research Associate, Department of Biomedical Engineering, Boston University, Boston, Mass.

2006 -2010 Graduate Research Associate, School of Chemical Engineering, Purdue University, West Lafayette, Ind.

2005 -2006 Undergraduate Research Assistant, Seoul National University, Seoul, Korea

2022 -To Present Associate Professor, Department of Chemical & Environmental Engineering Secondary: Department of Biomedical Engineering, Department of Ophthalmology, Department of Materials Science and Engineering, University of Cincinnati,

Research Support

Grant: #R40310 Investigators:Park, Yoonjee 05-01-2019 -12-31-2020 UC's Collaborative Research Advancement Grants Program - Track 2: Strategic Teams Strategic Collab Grant – Park, Yoonjee Role:PI $70,000.00 Active Level:Internal UC

Grant: #Check 1206 Adm 2018-19 Investigators:Kao, Winston Whei Yang; Park, Yoonjee 09-15-2018 -09-14-2019 Ohio Lions Eye Research Foundation “On-demand” Long-Term Drug Delivery for Age-Related Macular Degeneration Treatment Role:Collaborator $10,000.00 Awarded Level:Private Non-Profit

Grant: #CCTST KL2 Investigators: Park, Yoonjee 04-01-2018 -06-30-2020 CCTST NIH KL2 Scholar Program On-Demand"- Long-Term Drug Delivery for Chronic Posterior Eye Disease Treatment Role:PI $250,000

Grant: #Check # 1158 AMD Research Investigators:Kao, Winston Whei Yang; Park, Yoonjee 09-15-2017 -09-14-2018 Ohio Lions Eye Research Foundation “On-demand” Long-Term Drug Delivery for Age-Related Macular Degeneration Treatment Role:Collaborator $10,000.00 Active Level:Private Non-Profit

Grant: #URS Strategic Collaborative Grants AY2017-2018 Investigators:Park, Yoonjee 07-01-2017 -10-31-2017 UC's Research Support Light-Triggered Drug-Releasing Biodegradable Implant for Posterior Eye Disease Treatment Role:PI $10,000.00 Active Level:Internal UC

Grant: #URS Strategic Collaborative Grants AY2017-2018 Investigators:Park, Yoonjee 07-01-2017 -05-31-2018 UC's Research Support Light-Triggered Drug-Releasing Biodegradable Implant for Posterior Eye Disease Treatment - Phase 1 Role:PI $27,641.00 Active Level:Internal UC

Grant: #AMD Grant Investigators:Kao, Winston Whei Yang; Park, Yoonjee 09-15-2019 -09-14-2020 Ohio Lions Eye Research Foundation Biodegradable “On-demand” Drug Implant for Age-Related Macular Degeneration Treatment Role:Collaborator $10,000.00 Awarded Level:Private Non-Profit

Grant: #Sigma Xi G20200315110757208 Investigators:Park, Yoonjee 06-15-2020 -06-30-2021 Sigma Xi, The Scientific Research Society Dose-controllable and biodegradable drug delivery implants for posterior eye disease treatment Role:PI $2,500.00 Awarded Level:Private Non-Profit

Grant: #OLERF Neiderhauser AMD Investigators:Park, Yoonjee 09-15-2022 -09-14-2023 Ohio Lions Eye Research Foundation Long-term Antibody Implant for Age-Related Macular Degeneration Treatment in Vivo Role:PI 30000.00 Hold Level:Non Profit

Grant: #Lois Hagelberger Huebner Young Investigator Award 09-15-2020 -09-14-2021 Ohio Lions Eye Research Foundation Dose-Controlled Co-Delivery Implant For Chronic AMD Treatment Role:PI $107,000.00 Awarded Level:Private Non-Profit

Grant: #Lois Hagelberger Huebner Young Investigator Award 09-15-2020 -09-14-2021 Ohio Lions Eye Research Foundation Dose-Controlled Co-Delivery Implant For Chronic AMD Treatment Role:PI $107,000.00 Awarded Level:Private Non-Profit

Grant: #R21DC021038 Investigators:Dion, Gregory; Park, Yoonjee 05-01-2023 -04-30-2025 National Institute on Deafness and Other Communication Disor INJECTABLE, TUNABLE THERAPEUTIC IMPLANT TO REDUCE VOCAL FOLD SCAR Role:PI 241123.00

Grant: #R15EY031500 Investigators:Kao, Winston Whei Yang; Li, Kevin; Park, Yoonjee 07-01-2021 -06-30-2024 National Eye Institute Undergraduate Research for Doses-Controllable Drug Delivery Implants Role:PI 474519.00 Awarded Level:Federal

Grant: #R03TR004429 Investigators:Park, Yoonjee 07-01-2023 -06-30-2025 National Center for Advancing Translational Sciences Co-Delivery Dose-Controllable Implants for Advanced Chronic Eye Disease Treatment Role:PI 80062.00 Awarded Level:Federal

Grant: #AMD Research 09-15-2021 -09-14-2022 Ohio Lions Eye Research Foundation 3D-Printed Co-Delivery Drug Implant for Age-Related Macular Degeneration Treatment Role:PI 30000.00

Grant: #R21EB034840 Investigators:Dion, Gregory; Park, Yoonjee 04-01-2024 -03-31-2027 National Institute of Biomedical Imaging and Bioengineering INJECTABLE, TUNABLE CO-DELIVERY THERAPEUTIC IMPLANT TO REDUCE AIRWAY STENOSIS Role:PI 0.00 Hold Level:Federal

Grant: #AMD Research 09-15-2021 -09-14-2022 Ohio Lions Eye Research Foundation 3D-Printed Co-Delivery Drug Implant for Age-Related Macular Degeneration Treatment Role:PI 30000.00

Grant: #2R44EY030821-02 Investigators:Park, Yoonjee 12-01-2023 -11-30-2025 Abzyme Therapeutics, LLC Multi-specific long-acting antibodies for the treatment of retinal neovascular diseases Role:PI 831927.00 Hold Level:Industry

Grant: #OLERF Park AMD 09-15-2023 -09-14-2024 Ohio Lions Eye Research Foundation Long-Acting Implant Using Hollow Fiber Membranes for Age-Related Macular Degeneration Treatment In Vivo Role:PI 30000.00 Hold Level:Non Profit

Grant: #OLERF Park AMD 09-15-2023 -09-14-2024 Ohio Lions Eye Research Foundation Long-Acting Implant Using Hollow Fiber Membranes for Age-Related Macular Degeneration Treatment In Vivo Role:PI 30000.00 Hold Level:Non Profit

Grant: #R15EY031500- NCE Investigators:Kao, Winston; Li, Kevin; Park, Yoonjee 07-01-2021 -06-30-2025 National Eye Institute Undergraduate Research for Doses-Controllable Drug Delivery Implants Role:PI 0.00 Hold Level:Federal

Grant: #Check No. 1561 Investigators:Park, Yoonjee 09-15-2024 -09-14-2025 Ohio Lions Eye Research Foundation Light-Activated Axitinib & Bevacizumab Co-Delivery Implantfor Age-Related Macular Degeneration Treatment Role:PI 30000.00 Awarded Level:Non Profit

Publications

Peer Reviewed Publications

Yuan Z.; Das S.; Lazenby R.A.; White R.J.; Park Y.C. (09-20-2021. ) Repetitive drug releases from light-activatable micron-sized liposomes.Colloids and Surfaces A: Physicochemical and Engineering Aspects, , 625 , More Information

He X.; Yuan Z.; Gaeke S.; Kao W.W.Y.; Li S.K.; Miller D.; Williams B.; Park Y.C. (02-15-2021. ) Laser-Activated Drug Implant for Controlled Release to the Posterior Segment of the Eye.ACS Applied Bio Materials, , 4 (2 ) ,1461-1469 More Information

Das S.; Lazenby R.A.; Yuan Z.; White R.J.; Park Y.C. (04-07-2020. ) Effect of Laser Irradiation on Reversibility and Drug Release of Light-Activatable Drug-Encapsulated.Langmuir, , 36 (13 ) ,3573-3582 More Information

Nithianandam P.; Das S.; Park Y.C. (03-17-2020. ) Effect of Surfactant-Keratin Hydrolysate Interactions on the Hydration Properties of a Stratum Corne.Langmuir, , 36 (10 ) ,2543-2552 More Information

He X.; Yuan Z.; Kao W.; Miller D.; Li S.K.; Park Y.C. (03-16-2020. ) Size-Exclusive Nanoporous Biodegradable PLGA Capsules for Drug Delivery Implants and in Vivo Stabili.ACS Applied Bio Materials, , 3 (3 ) ,1722-1729 More Information

Yuan Z.; Demith A.; Stoffel R.; Zhang Z.; Park Y.C. (12-01-2019. ) Light-activated doxorubicin-encapsulated perfluorocarbon nanodroplets for on-demand drug delivery in.Colloids and Surfaces B: Biointerfaces, , 184 , More Information

Zhang Z.; Taylor M.; Kaval N.; Park Y. (06-13-2019. ) Phase-Transition Temperature of Gold-Nanorod-Coated Nanodroplets to Microbubbles by Pulsed Laser.Journal of Physical Chemistry A, , 123 (23 ) ,4844-4852 More Information

Zhang Z.; Taylor M.; Collins C.; Haworth S.; Shi Z.; Yuan Z.; He X.; Cao Z.; Park Y.C. (01-17-2018. ) Light-Activatable Theranostic Agents for Image-Monitored Controlled Drug Delivery.ACS Applied Materials and Interfaces, , 10 (2 ) ,1534-1543 More Information

Park Y.; Zhang C.; Kim S.; Mohamedi G.; Beigie C.; Nagy J.; Holt R.; Cleveland R.; Jeon N.; Wong J. (11-23-2016. ) Microvessels-on-a-chip to assess targeted ultrasound-assisted drug delivery.ACS Applied Materials and Interfaces, , 8 (46 ) ,31541-31549 More Information

Park Y.; Smith J.; Pham T.; Whitaker R.; Sucato C.; Hamilton J.; Bartolak-Suki E.; Wong J. (07-01-2014. ) Effect of PEG molecular weight on stability, T2 contrast, cytotoxicity, and c.Colloids and Surfaces B: Biointerfaces, , 119 ,106-114 More Information

Park Y.; Paulsen J.; Nap R.; Whitaker R.; Mathiyazhagan V.; Song Y.; Hürlimann M.; Szleifer I.; Wong J. (01-28-2014. ) Adsorption of superparamagnetic iron oxide nanoparticles on silica and calcium carbonate sand.Langmuir, , 30 (3 ) ,784-792 More Information

Park Y.; Zhang C.; Mohamedi G.; Kim S.; Jeon N.; Cleveland R.; Nagy J.; Wong J. (01-01-2014. ) Ultrasound-assisted drug delivery with targeted-microbubbles in blood vessels on a chip.Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC, , 2014-December , More Information

Park Y.; Whitaker R.D.; Nap R.J.; Paulsen J.L.; Mathiyazhagan V.; Doerrer L.H.; Song Y.Q.; Hürlimann M.D.; Szleifer I.; Wong J.Y. (04-17-2012. ) Stability of superparamagnetic iron oxide nanoparticles at different pH values: Experimental and the.Langmuir, , 28 (15 ) ,6246-6255 More Information

Park Y.; Luce A.C.; Whitaker R.D.; Amin B.; Cabodi M.; Nap R.J.; Szleifer I.; Cleveland R.O.; Nagy J.O.; Wong J.Y. (02-28-2012. ) Tunable diacetylene polymerized shell microbubbles as ultrasound contrast agents.Langmuir, , 28 (8 ) ,3766-3772 More Information

Mohamedi G.; Hosny N.; Rademeyer P.; Park Y.; Owen J.; Pham T.; Wong J.; Kuimova M.; Stride E. (06-19-2013. ) Investigating the effect of fabrication method on the stability and acoustic response of microbubble.Proceedings of Meetings on Acoustics, , 19 , More Information

Nap R.J.; Park Y.; Wong J.Y.; Szleifer I. (11-26-2013. ) Adsorption of acid and polymer coated nanoparticles: A statistical thermodynamics approach.Langmuir, , 29 (47 ) ,14482-14493 More Information

Park Y.; Pham T.A.; Beigie C.; Cabodi M.; Cleveland R.O.; Nagy J.O.; Wong J.Y. (09-15-2015. ) Monodisperse Micro-Oil Droplets Stabilized by Polymerizable Phospholipid Coatings as Potential Drug .Langmuir, , 31 (36 ) ,9762-9770 More Information

Park Y. (07-23-2015. ) Nanoparticles for imaging and non-viral gene therapy.Biomedical Engineering: Frontier Research and Converging Technologies, , 9 ,3-18 More Information

Nguyen K.; Pan H.Y.; Haworth K.; Mahoney E.; Mercado-Shekhar K.P.; Lin C.Y.; Zhang Z.; C. Park Y. (01-01-2019. ) Multiple-Exposure Drug Release from Stable Nanodroplets by High-Intensity Focused Ultrasound for a P.Ultrasound in Medicine and Biology, , 45 (1 ) ,160-169 More Information

Yuan Z.; Das S.; Do C.; Park Y.C. (05-20-2022. ) Effect of cholesterol on nano-structural alteration of light-activatable liposomes via laser irradia.Colloids and Surfaces A: Physicochemical and Engineering Aspects, , 641 , More Information

Yuan Z.; Gottsacker C.; He X.; Waterkotte T.; Park Y.C. (08-01-2022. ) Repetitive drug delivery using Light-Activated liposomes for potential antimicrobial therapies.Advanced Drug Delivery Reviews, , 187 , More Information

Waterkotte T.; He X.; Wanasathop A.; Li S.K.; Park Y.C. (10-10-2022. ) Long-Term Antibody Release Polycaprolactone Capsule and the Release Kinetics in Natural and Accelera.ACS Biomaterials Science and Engineering, , 8 (10 ) ,4428-4438 More Information

Debele, Tilahun Ayane; Park, Yoonjee (2022. ) Application of Nanoparticles: Diagnosis, Therapeutics, and Delivery of Insulin/Anti-Diabetic Drugs to Enhance the Therapeutic Efficacy of Diabetes Mellitus.Life (Basel, Switzerland), , 12 (12 ) , More Information

Yuan, Zheng; Das, Saikat; Do, Changwoo; Park, Yoonjee C (2022. ) Effect of Cholesterol on Nano-Structural Alteration of Light-Activatable Liposomes via Laser Irradiation: Small Angle Neutron Scattering Study.Colloids and surfaces. A, Physicochemical and engineering aspects, , 641 , More Information

Yuan, Zheng; Das, Saikat; Lazenby, Robert A; White, Ryan J; Park, Yoonjee C (2021. ) Repetitive drug releases from light-activatable micron-sized liposomes.Colloids and surfaces. A, Physicochemical and engineering aspects, , 625 , More Information

He, Xingyu; Yuan, Zheng; Gaeke, Samantha; Kao, Winston W-Y; Li, S Kevin; Miller, Daniel; Williams, Basil; Park, Yoonjee C (2021. ) Laser-Activated Drug Implant for Controlled Release to the Posterior Segment of the Eye.ACS applied bio materials, , 4 (2 ) ,1461-1469 More Information

He, Xingyu; Yuan, Zheng; Kao, Winston; Miller, Daniel; Li, S Kevin; Park, Yoonjee C (2020. ) Size-Exclusive Nanoporous Biodegradable PLGA Capsules for Drug Delivery Implants and In Vivo Stability in the Posterior Segment.ACS applied bio materials, , 3 (3 ) ,1722-1729 More Information

Ventura, Stephanie A; Heikenfeld, Jason; Brooks, Tiffany; Esfandiari, Leyla; Boyce, Steven; Park, Yoonjee; Kasting, Gerald B (2017. ) Cortisol extraction through human skin by reverse iontophoresis.Bioelectrochemistry (Amsterdam, Netherlands), , 114 ,54-60 More Information

Honors and Awards

2018 Faculty Development Awards (full review) Univ. of Cincinnati

2018 Ohio Lion Eye Research Foundation AMD Award

2018 NIH KL2 Scholar Program Award

2017 Ohio Lion Eye Research Foundation AMD Award

2016 CCC Jensen Symposium Registration Award Univ. of Cincinnati

2016 Health Research Rising Stars Award Univ. of Cincinnati

2015 KIChE President Young Investigator Award

2015 Faculty Development Awards Univ. of Cincinnati

2013 NSF ADVANCE future faculty workshop selected participant

2009 Travel grant for invited speakers US-Korea Conference 2009

2005 -2006 Seoul National University scholarship with Honor

2004 -2005 Special Development Scholarship Seoul National University

2003 -2004 Seoul National University scholarship

2019 Ohio Lion Eye Research Foundation AMD Award

2020 Sigma Xi Grant-In-Aid Vision Research

2020 CCTST Mentored Pilot Translational Research Program Grant Award

2020 Lois Hagelberger Huebner Young Investigator Award – OLERF

2021 Ohio Lion Eye Research Foundation AMD Award

2021 NIH Academic Research Enhancement Awards (R15)

2022 UC Sponsored Research Award

2022 CEAS Distinguished Research Award