Rajamouli Pasula , PhD
Research Associate
Research Assistant
Medical Sciences Building
231 Albert Sabin Way
Cincinnati, Ohio 45267
Phone (513) 558-4704
Fax (513) 558-0566
Email rajamouli.pasula@uc.edu
Education
Bachelor's Degree: Kakatiya University 1980 (Botany, Zoology and Chemistry)
Master's Degree: Osmania University 1983 (Microbiology)
Doctoral Degree: All India Institute of Medical Sciences 1990 (Microbiology)
Fellowship: Indiana University School of Medicine 1992 (Microbiology and Immunology)
Fellowship: Indiana University School of Medicine 1994 (Pulmonary Division)
Research and Practice Interests
Immuno-Pathogenesis of Pulmonary Infections
Positions and Work Experience
1994 -1998 Research Associate, Pulmonary Division, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN
1998 -2002 Assistant Scientist, Pulmonary Division, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN
2002 -To Present Research Asst. Professor, University of Cincinnati, College of Internal Medicine, Cincinnati, OH
Research Support
10-01-2009 -09-30-2013 VA Merit Review Award Iron Acquisition by Mycobacteria Residing Within Macrophages Role:Co-PI
R21 Mechanisms of silica induced susceptibility to mycobacterial infection Role:PI
R01 Cell Based Therapy for Tb infections Role:PI
03-01-2006 -11-30-2009 NHLBI (R01) Alveolar macrophage and mycobacteria Role:PI $225,000
09-30-2002 -09-29-2005 NHLBI (R01) Alveolar tissuegenesis Role:Co-PI $150,000
09-01-1995 -08-31-2000 NHLBI (R01) Tuberculosis, HIV and surfactant proteins Role:Co-PI $190,928
09-29-1997 -09-30-2002 NHLBI (R01) Progressive Impairment of HIV infection Role:Co-PI $175,000
Grant: #R01 HL076955 Investigators:Pasula, Rajamouli 09-22-2003 -08-31-2009 National Heart, Lung and Blood Institute Alveolar Macrophage and Mycobacteria Role:PI $1,710,643.00 Closed Level:Federal
Grant: #SRS 007783 Investigators:Pasula, Rajamouli 08-01-2011 -07-31-2013 Department of Veterans Affairs Intergovernmental Personnel Act Agreement for Raj Pasula Role:PI $94,002.53 Active Level:Federal
Grant: #VA IPA-Pasula Investigators:Pasula, Rajamouli 09-01-2014 -08-31-2016 Department of Veterans Affairs VA IPA PASULA 2014-2015 Role:PI $180,797.37 Active Level:Federal
Publications
Peer Reviewed Publications
Pasula, Rajamouli; Britigan, Bradley E; Turner, Joanne; Martin, William J (2009. ) Airway delivery of silica increases susceptibility to mycobacterial infection in mice: potential role of repopulating macrophages.Journal of immunology (Baltimore, Md. : 1950), , 182 (11 ) ,7102-9 More Information
Young, Lisa R; Pasula, Rajamouli; Gulleman, Peter M; Deutsch, Gail H; McCormack, Francis X (2007. ) Susceptibility of Hermansky-Pudlak mice to bleomycin-induced type II cell apoptosis and fibrosis.American journal of respiratory cell and molecular biology, , 37 (1 ) ,67-74 More Information
Martin, William J; Wu, Min; Pasula, Rajamouli (2005. ) A novel approach to restore lung immunity during systemic immunosuppression. Transactions of the American Clinical and Climatological Association, , 116 ,221-6; discussion 22
Day, Richard B; Wang, Yana; Knox, Kenneth S; Pasula, Rajamouli; Martin, William J; Twigg, Homer L (2004. ) Alveolar macrophages from HIV-infected subjects are resistant to Mycobacterium tuberculosis in vitro.American journal of respiratory cell and molecular biology, , 30 (3 ) ,403-10 More Information
Pasula, Rajamouli; Weaver, Todd; Martinez, Manuel A; Martin, William J (2002. ) Morphologic detection and functional assessment of reconstituted normal alveolar macrophages in the lungs of SCID mice. Journal of immunology (Baltimore, Md. : 1950), , 169 (8 ) ,4504-10
Pasula, Rajamouli; Wisniowski, Paul; Martin, William J (2002. ) Fibronectin facilitates Mycobacterium tuberculosis attachment to murine alveolar macrophages. Infection and immunity, , 70 (3 ) ,1287-92
Reszka, Krzysztof J; Xiong, Ye; Sallans, Larry; Pasula, Rajamouli; Olakanmi, Oyebode; Hassett, Daniel J; Britigan, Bradley E (2012. ) Inactivation of the potent Pseudomonas aeruginosa cytotoxin pyocyanin by airway peroxidases and nitrite.American journal of physiology. Lung cellular and molecular physiology, , 302 (10 ) ,L1044-56 More Information
Pasula, Rajamouli; Azad, Abul K; Gardner, Jason C; Schlesinger, Larry S; McCormack, Francis X (2015. ) Keratinocyte Growth Factor Administration Attenuates Murine Pulmonary Mycobacterium tuberculosis Infection through Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF)-dependent Macrophage Activation and Phagolysosome Fusion.The Journal of biological chemistry, , 290 (11 ) ,7151-9 More Information
Olakanmi, Oyebode; Kesavalu, Banurekha; Pasula, Rajamouli; Abdalla, Maher Y; Schlesinger, Larry S; Britigan, Bradley E (2013. ) Gallium nitrate is efficacious in murine models of tuberculosis and inhibits key bacterial Fe-dependent enzymes.Antimicrobial agents and chemotherapy, , 57 (12 ) ,6074-80 More Information
Keywords
research, pulmonary, innate immunity
Contact Information
Academic - Medical Sciences Building
231 Albert Sabin Way
CincinnatiĀ
Ohio, 45267
Phone: (513) 558-4704
Fax: (513) 558-0566
rajamouli.pasula@uc.edu