Rajamouli Pasula

Rajamouli Pasula, PhD

Research Associate

Research Assistant

Medical Sciences Building
231 Albert Sabin Way
Cincinnati, Ohio 45267
Phone (513) 558-4704
Fax (513) 558-0566
Email rajamouli.pasula@uc.edu

Education

Bachelor's Degree: Kakatiya University 1980 (Botany, Zoology and Chemistry)

Master's Degree: Osmania University 1983 (Microbiology)

Doctoral Degree: All India Institute of Medical Sciences 1990 (Microbiology)

Fellowship: Indiana University School of Medicine 1992 (Microbiology and Immunology)

Fellowship: Indiana University School of Medicine 1994 (Pulmonary Division)

Research and Practice Interests

Immuno-Pathogenesis of Pulmonary Infections

Positions and Work Experience

1994 -1998 Research Associate, Pulmonary Division, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN

1998 -2002 Assistant Scientist, Pulmonary Division, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN

2002 -To Present Research Asst. Professor, University of Cincinnati, College of Internal Medicine, Cincinnati, OH

Research Support

10-01-2009 -09-30-2013 VA Merit Review Award Iron Acquisition by Mycobacteria Residing Within Macrophages Role:Co-PI

R21 Mechanisms of silica induced susceptibility to mycobacterial infection Role:PI

R01 Cell Based Therapy for Tb infections Role:PI

03-01-2006 -11-30-2009 NHLBI (R01) Alveolar macrophage and mycobacteria Role:PI $225,000

09-30-2002 -09-29-2005 NHLBI (R01) Alveolar tissuegenesis Role:Co-PI $150,000

09-01-1995 -08-31-2000 NHLBI (R01) Tuberculosis, HIV and surfactant proteins Role:Co-PI $190,928

09-29-1997 -09-30-2002 NHLBI (R01) Progressive Impairment of HIV infection Role:Co-PI $175,000

Grant: #R01 HL076955 Investigators:Pasula, Rajamouli 09-22-2003 -08-31-2009 National Heart, Lung and Blood Institute Alveolar Macrophage and Mycobacteria Role:PI $1,710,643.00 Closed Level:Federal

Grant: #SRS 007783 Investigators:Pasula, Rajamouli 08-01-2011 -07-31-2013 Department of Veterans Affairs Intergovernmental Personnel Act Agreement for Raj Pasula Role:PI $94,002.53 Active Level:Federal

Grant: #VA IPA-Pasula Investigators:Pasula, Rajamouli 09-01-2014 -08-31-2016 Department of Veterans Affairs VA IPA PASULA 2014-2015 Role:PI $180,797.37 Active Level:Federal

Publications

Peer Reviewed Publications

Pasula, Rajamouli; Britigan, Bradley E; Turner, Joanne; Martin, William J  (2009). Airway delivery of silica increases susceptibility to mycobacterial infection in mice: potential role of repopulating macrophages. Journal of immunology (Baltimore, Md. : 1950), 182 (11) , 7102-9More Information

Young, Lisa R; Pasula, Rajamouli; Gulleman, Peter M; Deutsch, Gail H; McCormack, Francis X  (2007). Susceptibility of Hermansky-Pudlak mice to bleomycin-induced type II cell apoptosis and fibrosis. American journal of respiratory cell and molecular biology, 37 (1) , 67-74More Information

Martin, William J; Wu, Min; Pasula, Rajamouli  (2005). A novel approach to restore lung immunity during systemic immunosuppression. Transactions of the American Clinical and Climatological Association, 116, 221-6; discussion 22

Day, Richard B; Wang, Yana; Knox, Kenneth S; Pasula, Rajamouli; Martin, William J; Twigg, Homer L  (2004). Alveolar macrophages from HIV-infected subjects are resistant to Mycobacterium tuberculosis in vitro. American journal of respiratory cell and molecular biology, 30 (3) , 403-10More Information

Pasula, Rajamouli; Weaver, Todd; Martinez, Manuel A; Martin, William J  (2002). Morphologic detection and functional assessment of reconstituted normal alveolar macrophages in the lungs of SCID mice. Journal of immunology (Baltimore, Md. : 1950), 169 (8) , 4504-10

Pasula, Rajamouli; Wisniowski, Paul; Martin, William J  (2002). Fibronectin facilitates Mycobacterium tuberculosis attachment to murine alveolar macrophages. Infection and immunity, 70 (3) , 1287-92

Reszka, Krzysztof J; Xiong, Ye; Sallans, Larry; Pasula, Rajamouli; Olakanmi, Oyebode; Hassett, Daniel J; Britigan, Bradley E  (2012). Inactivation of the potent Pseudomonas aeruginosa cytotoxin pyocyanin by airway peroxidases and nitrite. American journal of physiology. Lung cellular and molecular physiology, 302 (10) , L1044-56More Information

Pasula, Rajamouli; Azad, Abul K; Gardner, Jason C; Schlesinger, Larry S; McCormack, Francis X  (2015). Keratinocyte Growth Factor Administration Attenuates Murine Pulmonary Mycobacterium tuberculosis Infection through Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF)-dependent Macrophage Activation and Phagolysosome Fusion. The Journal of biological chemistry, 290 (11) , 7151-9More Information

Olakanmi, Oyebode; Kesavalu, Banurekha; Pasula, Rajamouli; Abdalla, Maher Y; Schlesinger, Larry S; Britigan, Bradley E  (2013). Gallium nitrate is efficacious in murine models of tuberculosis and inhibits key bacterial Fe-dependent enzymes. Antimicrobial agents and chemotherapy, 57 (12) , 6074-80More Information

Keywords

research, pulmonary, innate immunity

Contact Information

Academic - Medical Sciences Building
231 Albert Sabin Way
Cincinnati  Ohio, 45267
Phone: (513) 558-4704
Fax: (513) 558-0566
rajamouli.pasula@uc.edu