Sarah Pixley

Sarah Katherine Pixley , PhD

Associate Professor

Office: MSB 4206A
Dept. of Pharmacology & Systems Physiology
231 Albert Sabin Way
Cincinnati, Ohio 45267-0576
Phone (513)558-6086
Fax (513)558-5738
Email sarah.pixley@uc.edu

Professional Summary

 
Research in the Pixley lab has moved from a past emphasis on the neurogenesis and neuropharmacology of the olfactory system into more applied neural tissue repair work. Our current focus is on using novel biomaterials to promote neural tissue repair and regeneration. One of the most promising biomaterials is magnesium, primarily in metal form. Magnesium metal has properties that have increasingly attracted attention in recent years for use as a bioresorbable biomedical implant material. The most advanced uses are currently as bone fixation devices and as a cardiovascular stent material. Magnesium metal is strong initially, then very safely resorbs into the body. We are identifying novel ways to use magnesium metal to improve recovery of nervous tissues from injury damage, focusing first on repairing injury cuts in peripheral nerves in rats. We are also exploring the use of ionic magnesium for nervous tissue repair. Magnesium in ionic form is known to be neuroprotective and aids recovery of brain tissues after traumatic injury or stroke. Magnesium ions reduce secondary neuronal damage that occurs after the initial injury and reduce vasospasm that occurs in the brain after damage and is also damagine. Our collaborative group includes surgeons, neurobiologists, neuropathologists, and engineers from many categories. We are currently funded by an NSF grant that supports an Engineering Research Center dedicated to Revolutionizing Metallic Biomaterials (http://erc.ncat.edu/).  As a second focus, the lab is exploring the use of carbon nanotube (CNT) materials for nervous tissue repair. Expert engineering groups at UC produce novel forms of CNT materials, which are linear biomaterials with promise for promoting neuronal outgrowth and repair. Our initial work shows that neuronal stem cells migrate readily along CNT thread and complete differentiation. We are also using CNT materials to guide nervous tissue repair. 

Education

Associate's Degree: Smith College Northampton, Massachusets, 1974 (Zoology)

Master's Degree: University of California at Los Angeles (UCLA) Los Angeles, CA, 1975 (Physiology)

Doctoral Degree: University of California at Los Angeles (UCLA) Los Angeles, CA, 1983 (Anatomy)

Postdoctoral: Cedars-Sinai Medical Center Los Angeles, CA, 1987 ( )

Postdoctoral: University of California Irvine, CA, 1985

Research and Practice Interests

Research in the Pixley lab has moved from a past emphasis on the neurogenesis and neuropharmacology of the olfactory system into more applied neural tissue repair work. Our current focus is on using novel biomaterials to promote neural tissue repair and regeneration. One of the most promising biomaterials is magnesium, primarily in metal form. Magnesium metal has properties that have increasingly attracted attention in recent years for use as a bioresorbable biomedical implant material. The most advanced uses are currently as bone fixation devices and as a cardiovascular stent material. Magnesium metal is strong initially, then very safely resorbs into the body. We are identifying novel ways to use magnesium metal to improve recovery of nervous tissues from injury damage, focusing first on repairing injury cuts in peripheral nerves in rats. We are also exploring the use of ionic magnesium for nervous tissue repair. Magnesium in ionic form is known to aid recovery of brain tissues after traumatic injury or stroke. Raising magnesium ions reduces secondary neuronal damage that occurs after the initial injury and reduces vasospasm in the brain after damage. Our collaborative group includes surgeons, neurobiologists, neuropathologists, and engineers. We are currently funded by an NSF grant that supports an Engineering Research Center dedicated to Revolutionizing Metallic Biomaterials (http://erc.ncat.edu/).  As a second focus, the lab is exploring the use of carbon nanotube (CNT) materials for nervous tissue repair. Expert engineering groups at UC produce novel forms of CNT materials, which are linear biomaterials with promise for promoting neuronal outgrowth and repair. Our initial work shows that neuronal stem cells migrate readily along CNT thread and complete differentiation. We are also using CNT materials to guide nervous tissue repair. 

Research Support

Grant: #NSF EEC-0812348 Investigators:PI: Jag Sankar 09-01-2008 -08-31-2019 NSF Engineering Research Center: "Revolutionizing Metallic Biomaterials", Subproject: Biosensors and Neural Applications Role:PI of Subproject Active Type:Grant Level:International

Grant: #260116C / EEC-0812348 Investigators:Pixley, Sarah; Schulz, Mark; Shanov, Vesselin 01-01-2010 -12-31-2012 National Science Foundation ERC: Revolutionizing Metallic Biomaterials, Supplemental Role:Collaborator $64,999.00 Active Type:Grant Level:International

Grant: #SRS 008475 Investigators:Pixley, Sarah 07-01-2013 -06-30-2014 American Association for Hand Surgery Peripheral Nerve Repair with Bioresorbable Metal Role:PI $10,000.00 Completed

Grant: #VA IPA - Hopkins Investigators:Hopkins, Tracy; Pixley, Sarah; Wagner, Kenneth 03-01-2013 -08-31-2013 Department of Veterans Affairs Intergovernmental Personnel Act Agreement - Hopkins Role:Collaborator $15,108.00 Completed

Grant: #000035 Investigators:Pixley, Sarah 11-11-2005 -11-30-2007 Janssen Pharmaceutica Research Foundation Neuroprotective Effects of Paliperidone: A Controlled Study of its Neurogenic Effects in the Olfactory Neuroepithlium Role:PI $249,563.00 Closed Level:Industry

Grant: #CORE Research Grant Investigators:Hershcovitch, Meir; Hom, David; Pixley, Sarah 07-01-2013 -06-30-2014 American Academy of Otolaryngology-Head and Neck Surgery Fou Nervous Tissue Repair Role:Collaborator $5,000.00 Completed Type:Fellowship Level:National

Grant: #5-P01-DC-00347-13-A0-S0-E0 Investigators:Pixley, Sarah 09-01-1994 -08-31-1999 National Institute on Deafness and Other Communication Disor Differentiation of Olfactory Receptor Neurons in Culture Role:PI $861,568.00 Closed Level:Federal

Investigators:Pixley, S.K. 09-01-2015 -08-31-2016 NSF LEAF grant to Univ. of Cincinnati The development of magnesium metal-containing fabric for wound repair Role:PI 3,000 Active Type:Grant Level:University

Grant: #190501_Ben Gurion Univ Investigators:Pixley, Sarah 05-01-2019 -07-01-2020 Ben-Gurion University of the Negev Nerve Regeneration using Biodegradable Zn alloy Scaffold Role:PI $45,500.00 Awarded Level:Foreign Institution of Higher Education

Grant: #R01NS134804 Investigators:Collar, Ryan; Esfandiari, Leyla; Harris, Gregory; Niu, Liang; Pixley, Sarah 01-01-2024 -12-31-2028 National Institute of Neurological Disorders and Stroke Developing multi-cue piezoelectric PVDF-TrFE biomaterials for peripheral nerve repair Role:Collaborator 441060.00 Awarded Level:Federal

Publications

Peer Reviewed Publications

Nasrallah, Henry A; Hopkins, Tracy; Pixley, Sarah K (2010. ) Differential effects of antipsychotic and antidepressant drugs on neurogenic regions in rats.Brain research, , 1354 ,23-9 More Information

Loftspring, M C; Smanik, J; Gardner, C; Pixley, S K (2008. ) Selective gray matter staining of human brain slices: optimized use of cadaver materials.Biotechnic & histochemistry : official publication of the Biological Stain Commission, , 83 (3 ) ,173-7 More Information

Ferrari, Carina C; Johnson, Brett A; Leon, Michael; Pixley, Sarah K (2003. ) Spatiotemporal distribution of the insulin-like growth factor receptor in the rat olfactory bulb .Neurochemical research, , 28 (1 ) ,29-43

McEntire, J K; Pixley, S K (2000. ) Olfactory receptor neurons in partially purified epithelial cell cultures: comparison of techniques for partial purification and identification of insulin as an important survival factor. Chemical senses, , 25 (1 ) ,93-101

Koster, N L; Norman, A B; Richtand, N M; Nickell, W T; Puche, A C; Pixley, S K; Shipley, M T (1999. ) Olfactory receptor neurons express D2 dopamine receptors. The Journal of comparative neurology, , 411 (4 ) ,666-73

Pixley, S K; Dangoria, N S; Odoms, K K; Hastings, L (1998. ) Effects of insulin-like growth factor 1 on olfactory neurogenesis in vivo and in vitro. Annals of the New York Academy of Sciences, , 855 ,244-7

Szucsik, J C; Witte, D P; Li, H; Pixley, S K; Small, K M; Potter, S S (1997. ) Altered forebrain and hindbrain development in mice mutant for the Gsh-2 homeobox gene.Developmental biology, , 191 (2 ) ,230-42 More Information

Pixley, S K; Farbman, A I; Menco, B P (1997. ) Monoclonal antibody marker for olfactory sustentacular cell microvilli. The Anatomical record, , 248 (3 ) ,307-21

Grill, R J; Pixley, S K (1997. ) In vitro generation of adult rat olfactory sensory neurons and regulation of maturation by coculture with CNS tissues. The Journal of neuroscience : the official journal of the Society for Neuroscience, , 17 (9 ) ,3120-7

Pixley, S K (1996. ) Characterization of olfactory receptor neurons and other cell types in dissociated rat olfactory cell cultures. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, , 14 (7-8 ) ,823-39

Lee, V M; Pixley, S K (1994. ) Age and differentiation-related differences in neuron-specific tubulin immunostaining of olfactory sensory neurons. Brain research. Developmental brain research, , 83 (2 ) ,209-15

Gong, Q; Bailey, M S; Pixley, S K; Ennis, M; Liu, W; Shipley, M T (1994. ) Localization and regulation of low affinity nerve growth factor receptor expression in the rat olfactory system during development and regeneration.The Journal of comparative neurology, , 344 (3 ) ,336-48 More Information

Pixley, S K; Bage, M; Miller, D; Miller, M L; Shi, M; Hastings, L (1994. ) Olfactory neurons in vitro show phenotypic orientation in epithelial spheres. Neuroreport, , 5 (5 ) ,543-8

Lu, S Y; Pixley, S K; Emerich, D F; Lehman, M N; Norman, A B. (1993. ) Effect of fetal striatal and astrocyte transplants into unilateral excitotoxin-lesioned striatum.Journal of neural transplantation & plasticity, , 4 (4 ) ,279-87 More Information

Grill, R J; Pixley, S K (1993. ) 2-Mercaptoethanol is a survival factor for olfactory, cortical and hippocampal neurons in short-term dissociated cell culture. Brain research, , 613 (1 ) ,168-72

Pixley, S K (1992. ) CNS glial cells support in vitro survival, division, and differentiation of dissociated olfactory neuronal progenitor cells. Neuron, , 8 (6 ) ,1191-204

Crowe, M J; Pixley, S K (1992. ) Species differences in amphibian olfactory neuron reactivity to a monoclonal antibody. Brain research bulletin, , 28 (5 ) ,785-8

Pixley, S K (1992. ) Purified cultures of keratin-positive olfactory epithelial cells: identification of a subset as neuronal supporting (sustentacular) cells.Journal of neuroscience research, , 31 (4 ) ,693-707 More Information

Pixley, S K (1992. ) The olfactory nerve contains two populations of glia, identified both in vivo and in vitro.Glia, , 5 (4 ) ,269-84 More Information

Crowe, M J; Pixley, S K (1991. ) Monoclonal antibody to carnosine synthetase identifies a subpopulation of frog olfactory receptor neurons. Brain research, , 538 (1 ) ,147-51

Pixley, S K; Pun, R Y (1990. ) Cultured rat olfactory neurons are excitable and respond to odors. Brain research. Developmental brain research, , 53 (1 ) ,125-30

Pixley, S K; Nieto-Sampedro, M; Cotman, C W (1987. ) Preferential adhesion of brain astrocytes to laminin and central neurites to astrocytes.Journal of neuroscience research, , 18 (3 ) ,402-6 More Information

Gibbs, R B; Pixley, S K; Cotman, C W (1986. ) Transplantation of septal neurons maintained in long-term culture. Brain research, , 382 (2 ) ,409-15

Pixley, S K; Cotman, C W (1986. ) Laminin supports short-term survival of rat septal neurons in low-density, serum-free cultures.Journal of neuroscience research, , 15 (1 ) ,1-17 More Information

Pixley, S K; de Vellis, J (1984. ) Transition between immature radial glia and mature astrocytes studied with a monoclonal antibody to vimentin. Brain research, , 317 (2 ) ,201-9

Pixley, S K; Kobayashi, Y; de Vellis, J (1984. ) A monoclonal antibody against vimentin: characterization. Brain research, , 317 (2 ) ,185-99

Pixley, S K; Kobayashi, Y; de Vellis, J (1984. ) Monoclonal antibody to intermediate filament proteins in astrocytes.Journal of neuroscience research, , 12 (4 ) ,525-41 More Information

Hopkins T, Vennemeyer J, Jayasinghe C, Shanov V + Pixley S (2010. ) Carbon nanotube ribbon and thread support attachment and differentiation of neural stem cells .NanoLife, , 1 (1-2 ) ,89-97

Yun, Y, Pixley, S, Cui, XT, Dong, Z, Collins, B, Shanov, V, Ko, S, Pai, D, Yarmolenko, S, Schulz, MJ, Sankar, J. (2012. ) Carbon nanomaterials: from therapeutics to regenerative medicine .Journal of Nanomedicine and Biotherapeutics Discovery, , 2 ,1

Schulz MJ, Doepke A, Guo X, Kuhlmann J, Halsall B, Heineman W, Dong Z, Tan Z, Xue D, Lee N, Yun Y, Liu Y, Hurd D, Shanov V, Rai D, Witte F, Kumar D, Yarmolenko S, Pixley SK, Hopkins T, Jayasinghe C, Sundaramurthy S (2010. ) Responsive biosensors for biodegradable magnesium implants .ASME Intl Mech Eng Congress & Expo Proc, , 14 ,109-116

Tong, J., Mannea, E., Aimé, P., Pfluger, P.T., Yi, C.-X., Castaneda, T.R., Davis, H.W., Ren, X., Pixley, S., Benoit, S., Julliard, K., Woods, S.C., Horvath, T.L., Sleeman, M.M., D'Alessio, D., Obici, S., Frank, R., Tschöp, M.H.. (2011. ) Ghrelin enhances olfactory sensitivity and exploratory sniffing in rodents and humans.Journal of Neuroscience, , 31 (15 ) ,5841–5846 More Information

Hopkins, Tracy M; Heilman, Alexander M; Liggett, James A; LaSance, Kathleen; Little, Kevin J; Hom, David B; Minteer, Danielle M; Marra, Kacey G; Pixley, Sarah K (2015. ) Combining micro-computed tomography with histology to analyze biomedical implants for peripheral nerve repair.Journal of neuroscience methods, , 255 ,122-30 More Information

Vennemeyer, J J; Hopkins, T; Hershcovitch, M; Little, K D; Hagen, M C; Minteer, D; Hom, D B; Marra, K; Pixley, S K (2015. ) Initial observations on using magnesium metal in peripheral nerve repair.Journal of biomaterials applications, , 29 (8 ) ,1145-54 More Information

Vennemeyer, John J; Hopkins, Tracy; Kuhlmann, Julia; Heineman, William R; Pixley, Sarah K (2014. ) Effects of elevated magnesium and substrate on neuronal numbers and neurite outgrowth of neural stem/progenitor cells in vitro.Neuroscience Research, , 84 ,72-78 More Information

Griebel, Adam J; Schaffer, Jeremy E; Hopkins, Tracy M; Alghalayini, Alaa; Mkorombindo, Tinomudaishe; Ojo, Kolade O; Xu, Zhigang; Little, Kevin J; Pixley, Sarah K (2018. ) An in vitro and in vivo characterization of fine WE43B magnesium wire with varied thermomechanical processing conditions.Journal of Biomedical Materials Research. Part B, Applied Biomaterials, , 106 (5 ) ,1987-1997

More Information

Hopkins, Tracy M; Little, Kevin J; Vennemeyer, John J; Triozzi, Jefferson L; Turgeon, Michael K; Heilman, Alexander M; Minteer, D; Marra, K; Hom, David B; Pixley, Sarah K (2017. ) Short and long gap peripheral nerve repair with magnesium metal filaments.Journal of biomedical materials research. Part A, , 105 (11 ) ,3148-3158 More Information

Pixley, Sarah K; Hopkins, Tracy M; Little, Kevin J; Hom, David B (2016. ) Evaluation of peripheral nerve regeneration through biomaterial conduits via micro-CT imaging.Laryngoscope investigative otolaryngology, , 1 (6 ) ,185-190 More Information

Adhikari U.;An X.;Sankar J.;Pixley S.;Bhattarai N. (01-01-2019. ) Fabrication of nanofibrous composite meshes incorporating mg metal particles for nerve repair applic .Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, , 40 ,409

Adhikari U.;An X.;Rijal N.;Hopkins T.;Khanal S.;Chavez T.;Tatu R.;Sankar J.;Little K.J.;Hom D.B.;Bhattarai N.;Pixley S.K. (01-01-2019. ) Embedding magnesium metallic particles in polycaprolactone nanofiber mesh improves applicability for.Acta Biomaterialia, , More Information

Kuhlmann J.;Guo X.;Zhang Z.;Hopkins T.;Wang T.;Ojo K.;Pixley S.;Heineman W. (05-01-2017. ) Electrochemical Sensors Continuously Monitor Magnesium Biodegradation under Cell Culture Conditions.Electroanalysis, , 29 (5 ) ,1341-1349 More Information

Ojo K.;Zhao D.;Rusinek C.;Pixley S.;Heineman W. (04-01-2017. ) Cathodic Stripping Voltammetric Determination of Cerium Using Indium Tin Oxide (ITO).Electroanalysis, , 29 (4 ) ,1124-1130 More Information

Ojo K.;Hopkins T.;Joshi M.;Salunke P.;Zhang G.;Nahan K.;Zhang Z.;Zhao D.;Pixley S.;Shanov V.;Heineman W. (12-01-2016. ) Conductivity as a Sensor for Monitoring Relative Magnesium Corrosion Rates in Real-time, in Serum-co.Electroanalysis, , 28 (12 ) ,3000-3008 More Information

Ojo K.;Kuhlmann J.;Hopkins T.;Heineman W.;Pixley S. (10-01-2016. ) Conductivity Sensor for Real-time Monitoring of Magnesium Corrosion under Cell Culture Conditions.Electroanalysis, , 28 (10 ) ,2522-2532 More Information

Hall A.M.;Hemmer R.;Spaulding R.;Wetzel H.N.;Curcio J.;Sabel B.A.;Henrich-Noack P.;Pixley S.;Hopkins T.;Boyce R.L.;Schultheis P.J.;Haik K.L. (08-08-2016. ) Cytotoxicity and apoptotic gene expression in an in vitro model of the blood–brain barrier following.Journal of Drug Targeting, , 24 (7 ) ,635-644 More Information

Edwards A.;Jarvis D.;Hopkins T.;Pixley S.;Bhattarai N. (01-01-2015. ) Poly(e-caprolactone)/keratin-based composite nanofibers for biomedical applications.Journal of Biomedical Materials Research - Part B Applied Biomaterials, , 103 (1 ) ,21-30 More Information

Alvarez N.;Ochmann T.;Kienzle N.;Ruff B.;Haase M.;Hopkins T.;Pixley S.;Mast D.;Schulz M.;Shanov V. (12-01-2014. ) Polymer coating of carbon nanotube fibers for electric microcables.Nanomaterials, , 4 (4 ) ,879-893 More Information

Schulz M.J.;Ruff B.;Johnson A.;Vemaganti K.;Li W.;Sundaram M.M.;Hou G.;Krishnaswamy A.;Li G.;Fialkova S.;Yarmolenko S.;Wang A.;Liu Y.;Sullivan J.;Alvarez N.;Shanov V.;Pixley S. (09-01-2013. ) New Applications and Techniques for Nanotube Superfiber Development.Nanotube Superfiber Materials: Changing Engineering Design, , 33-59 More Information

Tong J.;Mannea E.;Aimé P.;Pfluger P.;Yi C.;Castaneda T.;Davis H.;Ren X.;Pixley S.;Benoit S.;Julliard K.;Woods S.;Horvath T.;Sleeman M.;D'Alessio D.;Obici S.;Frank R.;Tschöp M. (04-13-2011. ) Ghrelin enhances olfactory sensitivity and exploratory sniffing in rodents and humans.Journal of Neuroscience, , 31 (15 ) ,5841-5846 More Information

Pai D.;Liles R.;Lambeth C.;Kumta P.;Borovetz H.;Pixley S.;Roy P.;Sankar J. (01-01-2011. ) Bootstrapping a new graduate curriculum through an Engineering Research Center .ASEE Annual Conference and Exposition, Conference Proceedings, ,

Schulz M.;Doepke A.;Guo X.;Kuhlmann J.;Halsall B.;Heineman W.;Dong Z.;Tan Z.;Xue D.;Lee N.;Yun Y.;Liu Y.;Hurd D.;Shanov V.;Rai D.;Witte F.;Kumar D.;Yarmolenko S.;Pixley S.;Hopkins T.;Jayasinghe C.;Sundaramurthy S. (01-01-2010. ) Responsive biosensors for biodegradable magnesium implants.ASME International Mechanical Engineering Congress and Exposition, Proceedings, , 14 ,109-116 More Information

Yun Y.H.;Shanov V.N.;Bange A.;Heineman W.R.;Halsall H.B.;Seth G.;Pixley S.K.;Behbehani M.;Bhattacharya A.;Dong Z.;Yarmolenko S.;Kang I.;Schulz M.J. (12-01-2009. ) Carbon nanotube smart materials for biology and medicine.NanoScience in Biomedicine, , 451-484 More Information

Yun Y.;Bange A.;Shanov V.N.;Heineman W.R.;Halsall H.B.;Dong Z.;Jazieh A.;Tu Y.;Wongs D.;Pixley S.;Behbehani M.;Schulz M.J. (07-01-2007. ) A carbon nanotube needle biosensor.Journal of Nanoscience and Nanotechnology, , 7 (7 ) ,2293-2300 More Information

Yun Y.H.;Bange A.;Heineman W.R.;Halsall H.B.;Shanov V.N.;Dong Z.;Pixley S.;Behbehani M.;Jazieh A.;Tu Y.;Wong D.K.Y.;Bhattacharya A.;Schulz M.J. (04-10-2007. ) A nanotube array immunosensor for direct electrochemical detection of antigen-antibody binding.Sensors and Actuators, B: Chemical, , 123 (1 ) ,177-182 More Information

Yun Y.H.;Bange A.;Shanov V.N.;Heineman W.R.;Brian Halsall H.;Dong Z.;Jazieh A.;Tu Y.;Wong D.;Pixley S.;Behbehani M.;Schulz M.J. (12-01-2006. ) Fabrication and characterization of a multiwall carbon nanotube needle biosensor .2006 6th IEEE Conference on Nanotechnology, IEEE-NANO 2006, , 1 ,280-283

Yun Y.;Bange A.;Shanov V.;Heineman W.;Brian Halsall H.;Pixley S.;Behbehani M.;Dong Z.;Tu Y.;Yarmolenko S.;Neralla S.;Schulz M. (07-20-2006. ) Carbon nanotube array smart materials.Proceedings of SPIE - The International Society for Optical Engineering, , 6172 , More Information

Yun Y.;Schulz M.;Bange A.;Heineman W.;Halsall H.;Shanov V.;Behbehani M.;Pixley S.;Bhattacharya A.;Dong Z.;Wong D. (06-01-2006. ) A nanotube composite microelectrode for monitoring dopamine levels using cyclic voltammetry and diff.Proceedings of the Institution of Mechanical Engineers, Part N: Journal of Nanoengineering and Nanosystems, , 220 (2 ) ,53-60 More Information

Pixley S.;Miller M. (12-01-1993. ) Cytoarchitecture of cultured olfactory neuroepithelial spheres: the role of olfactory sustentacular .Proceedings - Annual Meeting, Microscopy Society of America, , 408-409

Pixley S.;Weiss M.;Melmed S. (01-01-1987. ) IDentification of human growth hormone messenger ribonucleic acid in pituitary adenoma cells by in s.Journal of Clinical Endocrinology and Metabolism, , 65 (3 ) ,575-580 More Information

Fagin J.;Pixley S.;Slanina S.;Ong J.;Melmed S. (01-01-1987. ) Insulin-like growth factor i gene expression iii gh3 rat pituitary cells: Messenger ribonucleic acid.Endocrinology, , 120 (5 ) ,2037-2043 More Information

Adhikari, Udhab; An, Xiaoxian; Rijal, Nava; Hopkins, Tracy; Khanal, Shalil; Chavez, Tom; Tatu, Rigwed; Sankar, Jagannathan; Little, Kevin J; Hom, David B; Bhattarai, Narayan; Pixley, Sarah K (2019. ) Embedding magnesium metallic particles in polycaprolactone nanofiber mesh improves applicability for biomedical applications.Acta biomaterialia, , 98 ,215-234 More Information

Adhikari, Udhab; An, Xiaoxian; Rijal, Nava; Hopkins, Tracy; Khanal, Shalil; Chavez, Tom; Tatu, Rigwed; Sankar, Jagannathan; Little, Kevin J; Hom, David B; Bhattarai, Narayan; Pixley, Sarah K (2019. ) Embedding magnesium metallic particles in polycaprolactone nanofiber mesh improves applicability for biomedical applications.Acta biomaterialia, , 98 ,215-234 More Information

Pixley S.K.; Hopkins T.M.; Little K.J.; Hom D.B. (01-01-2016. ) Evaluation of peripheral nerve regeneration through biomaterial conduits via micro-CT imaging.Laryngoscope Investigative Otolaryngology, , 1 (6 ) ,185-190 More Information

Kandala B.S.P.K.; Zhang G.; Hopkins T.M.; An X.; Pixley S.K.; Shanov V. (11-01-2019. ) In vitro and in vivo testing of zinc as a biodegradable material for stents fabricated by photo-chem.Applied Sciences (Switzerland), , 9 (21 ) , More Information

Yin Z.; Dong Z.; Cahay M.; Pixley S.; Haworth K.J.; Rahimi M.; Goh S.K.; Starnes S.; Patwardhan M.; Chaudhary S.; Schulz M.J. (01-01-2019. ) Carbon nanotube wire for use in precision medical devices.Nanotube Superfiber Materials: Science, Manufacturing, Commercialization, , 825-849 More Information

Schulz M.J.; Li W.; Ruff B.; Venkatasubramanian R.; Song Y.; Suberu B.; Cho W.; Salunke P.; Sowani A.; Yin J.; Mast D.; Shanov V.; Dong Z.; Pixley S.; Hu J.; Muratore C. (01-01-2016. ) Sensorcyte Artificial Cells for Human Diagnostics and Analytics.Nanomedical Device and Systems Design: Challenges, Possibilities, Visions, , 401-453 More Information

Tatu R.; White L.G.; Yun Y.; Hopkins T.; An X.; Ashraf A.; Little K.J.; Hershcovitch M.; Hom D.B.; Pixley S. (02-01-2023. ) Effects of Altering Magnesium Metal Surfaces on Degradation In Vitro and In Vivo during Peripheral N.Materials, , 16 (3 ) , More Information

Ron T.; Leon A.; Kafri A.; Ashraf A.; Na J.; Babu A.; Banerjee R.; Brookbank H.; Muddaluri S.R.; Little K.J.; Aghion E.; Pixley S. (11-01-2023. ) Nerve Regeneration with a Scaffold Incorporating an Absorbable Zinc-2% Iron Alloy Filament to Improv.Pharmaceutics, , 15 (11 ) , More Information

Keywords

Nervous system repair, neural regeneration, magnesium, peripheral nerve, peripheral nerve injury, sciatic nerve, Tissue Engineering, biomedical implant, carbon nanotubes

Contact Information

Academic - Office: MSB 4206A
Dept. of Pharmacology & Systems Physiology
Cincinnati  Ohio, 45267-0576
Phone: (513)558-6086
Fax: (513)558-5738
sarah.pixley@uc.edu