Alexey Porollo

Alexey A Porollo

Assoc Professor

Biostatistics, Health Informatics and Data Sciences
260 Stetson Street
Suite 4200
Cincinnati, Ohio 45219
Email alexey.porollo@uc.edu

Professional Summary

Protein structure / function prediction and annotation.
Analysis of missense mutations.
Comparative genomics analysis.

Education

Master's Degree: Mari State University 1995

Doctoral Degree: Tver State University 1999

Postdoctorate: Children’s Hospital Medical Center 2006

Research and Practice Interests

Research Support

Grant: #R01 AI106269 Investigators:Caruso, Joseph; Deepe, George; Porollo, Alexey 05-15-2013 -04-30-2018 National Institute of Allergy and Infectious Diseases GM-CSF-Induced Metal Sequestration and Histoplasma Role:Collaborator $445,048.00 Active Level:Federal

Grant: #R01 HL119190 Investigators:Cushion, Melanie; Medvedovic, Mario; Porollo, Alexey 05-22-2013 -02-28-2018 National Heart, Lung and Blood Institute Directed Culturing of Pneumocystis Using Metatranscriptomics Role:Collaborator $404,514.00 Active Level:Federal

Grant: #P30ES006096 Investigators:Caruso, Joseph; Chen, Aimin; Deka, Ranjan; Greis, Kenneth; Haynes, Erin; Ho, Shuk Mei; Lemasters, Grace; Leung, Yuet Kin; Medvedovic, Mario; Meller, Jaroslaw; Meloncon, Lisa; Pinney, Susan; Porollo, Alexey; Puga, Alvaro; Thomas, Michael; Woo, Daniel; Yadav, Jagjit; Yancey, Elissa 04-01-2013 -03-31-2018 National Institute of Environmental Health Sciences Environmental Genetics Role:Collaborator $1,743,768.00 Active Level:Federal

Grant: #R21AI097936 Investigators:Meller, Jaroslaw; Porollo, Alexey 08-06-2013 -07-31-2015 National Institute of Allergy and Infectious Diseases Norovirus Capsid: A Novel Drug Target Role:Collaborator $197,749.00 Awarded Level:Federal

Publications

Peer Reviewed Publications

Albee, Aaron W; Sayson, Steven G; Ashbaugh, Alan; Wolf, Nicholas J; Porollo, Aleksey; Smulian, George; Cushion, Melanie T  (2025). Single-cell RNA sequencing defines developmental progression and reproductive transitions of Pneumocystis carinii. Microbiology spectrum, 13 (10) , e0127725More Information

Van Camp, Pieter-Jan; Prasath, V B Surya; Haslam, David B; Porollo, Aleksey  (2023). MGS2AMR: a gene-centric mining of metagenomic sequencing data for pathogens and their antimicrobial resistance profile. Microbiome, 11 (1) , 223More Information

Tran, Chau; Khadkikar, Siddharth; Porollo, Aleksey  (2023). Survey of Protein Sequence Embedding Models. International journal of molecular sciences, 24 (4) More Information

Van Camp, Pieter-Jan; Haslam, David B; Porollo, Aleksey  (2020). Prediction of Antimicrobial Resistance in Gram-Negative Bacteria From Whole-Genome Sequencing Data. Frontiers in microbiology, 11, 1013More Information

Baker, Frazier N; Porollo, Aleksey  (2016). CoeViz: a web-based tool for coevolution analysis of protein residues. BMC bioinformatics, 17, 119More Information

Porollo A, Sesterhenn TM, Collins MS, Welge JA, Cushion MT.  (11-2014). Comparative genomics of pneumocystis species suggests the absence of genes for myo-inositol synthesis and reliance on inositol transport and metabolism. MBio., 5 (6) , e01834More Information

Porollo, Aleksey; Meller, Jarosław  (2007). Prediction-based fingerprints of protein-protein interactions. Proteins, 66 (3) , 630-45More Information

Contact Information

Academic - Biostatistics, Health Informatics and Data Sciences
260 Stetson Street
Cincinnati  Ohio, 45219
alexey.porollo@uc.edu