Alexey Porollo

Alexey A Porollo

Associate Professor

Professional Summary

Protein structure / function prediction and annotation.
Analysis of missense mutations.
Comparative genomics analysis.


Master's Degree, Mari State University 1995

Doctoral Degree, Tver State University 1999

Postdoctorate, Children’s Hospital Medical Center 2006

Research and Practice Interests

Research Support

Grant: #R01 AI106269 Investigators:Caruso, Joseph; Deepe, George; Porollo, Alexey 05-15-2013 -04-30-2018 National Institute of Allergy and Infectious Diseases GM-CSF-Induced Metal Sequestration and Histoplasma Role:Collaborator $445,048.00 Active Level:Federal

Grant: #R01 HL119190 Investigators:Cushion, Melanie; Medvedovic, Mario; Porollo, Alexey 05-22-2013 -02-28-2018 National Heart, Lung and Blood Institute Directed Culturing of Pneumocystis Using Metatranscriptomics Role:Collaborator $404,514.00 Active Level:Federal

Grant: #P30ES006096 Investigators:Caruso, Joseph; Chen, Aimin; Deka, Ranjan; Greis, Kenneth; Haynes, Erin; Ho, Shuk Mei; Lemasters, Grace; Leung, Yuet Kin; Medvedovic, Mario; Meller, Jaroslaw; Meloncon, Lisa; Pinney, Susan; Porollo, Alexey; Puga, Alvaro; Thomas, Michael; Woo, Daniel; Yadav, Jagjit; Yancey, Elissa 04-01-2013 -03-31-2018 National Institute of Environmental Health Sciences Environmental Genetics Role:Collaborator $1,743,768.00 Active Level:Federal

Grant: #R21AI097936 Investigators:Meller, Jaroslaw; Porollo, Alexey 08-06-2013 -07-31-2015 National Institute of Allergy and Infectious Diseases Norovirus Capsid: A Novel Drug Target Role:Collaborator $197,749.00 Awarded Level:Federal


Peer Reviewed Publications

Baker FN, Porollo A. (2016. )CoeViz: a web-based tool for coevolution analysis of protein residues.BMC Bioinformatics., ,17 ,119

Porollo A, Sesterhenn TM, Collins MS, Welge JA, Cushion MT. (11-2014. )Comparative genomics of pneumocystis species suggests the absence of genes for myo-inositol synthesis and reliance on inositol transport and metabolism.MBio., ,5 (6 ),e01834

Syed K, Porollo A, Miller D, Yadav JS. (2013. )Rational engineering of the fungal P450 monooxygenase CYP5136A3 to improve its oxidizing activity toward polycyclic aromatic hydrocarbons.Protein Eng Des Sel., ,26 (9 ),553

Porollo A, Meller J. (2010. )POLYVIEW-MM: web-based platform for animation and analysis of molecular simulations.Nucleic Acids Res., ,38 ,W662

Porollo A, Meller J. (02-2007. )Prediction-based fingerprints of protein-protein interactions. Proteins., ,66 (3 ),630

Contact Information

Academic - Cincinnati Children's Hospital Medical Center
Cincinnati  Ohio, 45267
Phone: 513-803-5489