Amanda Pugh

Amanda Marie Pugh

Chief Resident in General Surgery

Education

Medical Degree, East Carolina University 2014

Bachelor's Degree, East Carolina University 2010 (Biology and Chemistry )

Positions and Work Experience

06-2008 -05-2009 Research Assistant, Department of Emergency Medicine, Brody School of Medicine, Greenville, NC (Mentor: Kori Brewer, PhD),

06-2009 -05-2010 Research Assistant, Department of Chemistry, East Carolina University, Greenville, NC (Mentor: Eli G. Hvastkovs, PhD),

Publications

Published Abstracts

Pugh AM, Brewer KL, Brown CK, Radecki RP (2010. ) 472: A previously validated risk score for late troponin elevation derived from TIMI IIIb and GUSTO IIa was not predictive when applied to a low-risk emergency department cohort .[Abstract]Annals of Emergency Medicine, 56 (3 ) ,S153

Peer Reviewed Publications

Rice, Teresa C; Pugh, Amanda M; Xia, Brent T; Seitz, Aaron P; Whitacre, Brynne E; Gulbins, Erich; Caldwell, Charles C (2017. ) Bronchoalveolar Lavage Microvesicles Protect Burn-Injured Mice from Pulmonary Infection.Journal of the American College of Surgeons, , 225 (4 ) ,538-547

Rice, Teresa C; Pugh, Amanda M; Caldwell, Charles C; Schneider, Barbara St Pierre (2017. ) Balance Between the Proinflammatory and Anti-Inflammatory Immune Responses with Blood Transfusion in Sepsis.Critical care nursing clinics of North America, , 29 (3 ) ,331-340

Pugh, Amanda M; Auteri, Nicholas J; Goetzman, Holly S; Caldwell, Charles C; Nomellini, Vanessa (2017. ) A Murine Model of Persistent Inflammation, Immune Suppression, and Catabolism Syndrome.International journal of molecular sciences, , 18 (8 ) ,

Mu, Xingjiang; Wang, Xiaohong; Huang, Wei; Wang, Rui-Tao; Essandoh, Kobina; Li, Yutian; Pugh, Amanda M; Peng, Jiangtong; Deng, Shan; Wang, Yigang; Caldwell, Charles C; Peng, Tianqing; Yu, Kai-Jiang; Fan, Guo-Chang (2017. ) Circulating Exosomes Isolated from Septic Mice Induce Cardiovascular Hyperpermeability Through Promoting Podosome Cluster Formation.Shock (Augusta, Ga.), ,

Rice, Teresa C; Pugh, Amanda M; Seitz, Aaron P; Gulbins, Erich; Nomellini, Vanessa; Caldwell, Charles C (2017. ) Sphingosine rescues aged mice from pulmonary pseudomonas infection.The Journal of surgical research, , 219 ,354-359

Satterwhite, Jennifer E; Pugh, Amanda M; Danell, Allison S; Hvastkovs, Eli G (2011. ) Electrochemical detection of anti-benzo[a]pyrene diol epoxide DNA damage on TP53 codon 273 oligomers.Analytical chemistry, , 83 (9 ) ,3327-35

Pugh AM, Silvestri BA, Ward MA, Whited WM, Capehart AA (2010. ) Unusual bilateral muscular variation in the medial forearm: Separate humeral and ulnar bellies of flexor carpi ulnaris and anomalous muscle addition.Anatomy: International Journal of Experimental & Clinical Anatomy, , 4 ,67-71

Baker, Jennifer E; Niziolek, Grace M; Elson, Nora C; Pugh, Amanda M; Nomellini, Vanessa; Makley, Amy T; Pritts, Timothy A; Goodman, Michael D (2019. ) Optimizing Lower Extremity Duplex Ultrasound Screening After Traumatic Injury.The Journal of surgical research, , 243 ,143-150

Martin, Grace E; Pugh, Amanda M; Moran, Ryan; Veile, Rose; Friend, Lou Ann; Pritts, Timothy A; Makley, Amy T; Caldwell, Charles C; Goodman, Michael D (2019. ) Microvesicles generated following traumatic brain injury induce platelet dysfunction via adenosine diphosphate receptor.The journal of trauma and acute care surgery, , 86 (4 ) ,592-600

Xia, Brent T; Beckmann, Nadine; Winer, Leah K; Pugh, Amanda M; Pritts, Timothy A; Nomellini, Vanessa; Gulbins, Erich; Caldwell, Charles C (2019. ) Amitriptyline Reduces Inflammation and Mortality in a Murine Model of Sepsis.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, , 52 (3 ) ,565-579

Beckmann, Nadine; Pugh, Amanda M; Caldwell, Charles C (2018. ) Burn injury alters the intestinal microbiome's taxonomic composition and functional gene expression.PloS one, , 13 (10 ) ,e0205307

Pugh, Amanda M; Giannini, Courtney M; Pinney, Susan M; Hanseman, Dennis J; Shaughnessy, Elizabeth A; Lewis, Jaime D (2018. ) Characteristics and diagnosis of pregnancy and lactation associated breast cancer: Analysis of a self-reported regional registry.American journal of surgery, , 216 (4 ) ,809-812

Martin G.;Pugh A.;Williams S.;Hanseman D.;Nomellini V.;Makley A.;Pritts T.;Goodman M. (03-01-2019. ) Lower Extremity Duplex Ultrasound Screening Protocol for Moderate and High Risk Trauma Patients.Journal of Surgical Research, , 235 ,280-287

Book Chapter

Pugh AM, Zhou J, Caldwell CC, Lehmann C (2017 ) Novel antibiotic approaches in sepsis Sepsis: Staging and Potential Future Therapies .(pp. 47-55).San Rafael, CA: Morgan & Claypoll Life Science

Pugh AM (2017 ) Abdominal trauma The Mont Reid Surgical Handbook, 7th ed .(pp. 203-19).Elsevier

Pugh AM (2017 ) Shock The Mont Reid Surgical Handbook, 7th ed .(pp. 159-70).Elsevier

Presentations

Poster Presentations

Satterwhite JE, Pugh AM, Danell AS, Hvastkovs EG (2009. ) Development of a sequence specific electrochemical genotoxicity biosensor .State of North Carolina Undergraduate Research and Creativity Symposium, Wilmington, NC. .

Pugh AM, Rice TC, Whitacre BE, et al (2016. ) Sphingosine rescues aged mice from pulmonary infection .Molecular Medicine of Sphingolipids International Conference, French Lick, IN. .

Paper Presentations

Pugh AM, Rice TC, Whitacre BE, et al (2016. ) Sphingosine rescues aged mice from pulmonary Pseudomonas aeruginosa infection .Molecular Medicine of Sphingolipids International Conference, French Lick, IN.

Pugh AM, Rice TC, Whitacre BE, et al (2016. ) Sphingosine rescues aged mice from pulmonary Pseudomonas aeruginosa infection .UC Symposium on Biomedicine of Sphingolipids, Cincinnati, OH.

Pugh AM, Nomellini V, Caldwell CC (2017. ) Towards a more clinically relevant murine sepsis model: cecal ligation and puncture with surgical and antibiotic source control .ACS Ohio Committee of Trauma, Cleveland, OH.

Pugh AM, Rice TC, Whitacre BE, et al (2017. ) Sphingosine rescues aged mice from pulmonary Pseudomonas aeruginosa infection .Academic Surgical Congress, Las Vegas, NV.

Pugh AM, Giannini CM, Pinney SM, et al (2017. ) Characteristics and diagnosis of pregnancy and lactation associated breast cancer: analysis of a self-reported regional registry .Association of Women Surgeons, San Diego, CA.

Pugh AM, Winer LK, Nomellini V, Caldwell CC (2018. ) Source control mitigates hypothermia and prevents lymphopenia in septic mice .Academic Surgical Congress, Jacksonville, FL.

Honors and Awards

2006 East Carolina Scholar and Early Assurance in Medicine Recipient

2010 Omicron Delta Kappa National Leadership Foundation Scholar

2014 Brody School of Medicine Surgery Award

2016 Association for Academic Surgery Fall Courses Travel Grant

2018 Winner, Basic Science Section, University of Cincinnati Department of Surgery 2017-2018 Resident Research Competition "Therapeutic sphingosine treatment is antimicrobial and enhances the immune response resulting in improved survival"

Service

Medical Student Council Curriculum Representative, ACGME Course and Clerkship Core Evaluation Task Force, Brody School of Medicine, Greenville, NC 08-2012 -05-2013

Summer Program for Future Doctors Teaching Assistant, Brody School of Medicine, Greenville, NC 05-2011 -08-2011

Medical Student Tutor, Brody School of Medicine, Greenville, NC 08-2011 -05-2013

Medical Student Surgery Interest Group Resident Advisor, University of Cincinnati College of Medicine, Cincinnati, OH 07-2017 -06-2018

Post Graduate Training and Education

07-2016-06-2018 Surgical Research Fellowship , Department of Surgery, University of Cincinnati, Cincinnati, OH (Mentor: Charles C. Caldwell, PhD),

Professional Affiliation

2008 -To Present: Omicron Delta Kappa National Leadership Honor Society

2008 -To Present: Phi Kappa Phi Honor Society

2010 -To Present: American Medical Association

2013 -To Present: American College of Surgeons, Resident Member

2013 -To Present: Alpha Omega Alpha

2014 -To Present: Association of Women Surgeons

2016 -To Present: Association for Academic Surgery

Contact Information

Academic - Medical Sciences Building
231 Albert Sabin Way
CincinnatiĀ  Ohio, 45267-0558
Phone: 513-558-4206
amanda.pugh@uc.edu