Adele Rike Shields, PharmD

Undergraduate Degree: University of Pittsburgh 1999 (Associate's Degree in Prepharmacy)

Pharmacy Degree: University of Pittsburgh School of Pharmacy 2003

Transplantation Pharmacy Specialty Residency and Fellowship: University of Cincinnati 2005

Grant: #0023660 (119158-1) / R01 AI096553 Investigators:Shields, Adele; Woodle, Ervin Steve 07-01-2011 -06-30-2015 National Institute of Allergy and Infectious Diseases Myfortic Preload Role:PI $254,663.00 Active Level:Federal

Grant: #U01FD004573 Investigators:Alloway, Rita; Kaiser, Tiffany; Sherman, Kenneth; Shields, Adele; Woodle, Ervin Steve 09-15-2012 -09-14-2015 Food and Drug Administration Pharmacokinetic Studies of Tacrolimus in Transplant Patients Role:Collaborator $2,691,189.00 Active Level:Federal

Grant: #HHSF223201310224C Investigators:Alloway, Rita; Kaiser, Tiffany; Shields, Adele 09-26-2013 -09-25-2016 Food and Drug Administration Evaluation of Clinical and Sfety Outcomes Associated with Conversion from Brand-Name to Generic Tacrolimus products in high risk Transplant Recipients Role:Collaborator $2,250,981.00 Awarded Level:Federal

Peer Reviewed Publications

Walsh, R Carlin; Everly, Jason J; Brailey, Paul; Rike, Adele H; Arend, Lois J; Mogilishetty, Gautham; Govil, Amit; Roy-Chaudhury, Prabir; Alloway, Rita R; Woodle, E Steve  (2010). Proteasome inhibitor-based primary therapy for antibody-mediated renal allograft rejection. Transplantation, 89 (3) , 277-84More Information

Everly, M J; Everly, J J; Arend, L J; Brailey, P; Susskind, B; Govil, A; Rike, A; Roy-Chaudhury, P; Mogilishetty, G; Alloway, R R; Tevar, A; Woodle, E S  (2009). Reducing de novo donor-specific antibody levels during acute rejection diminishes renal allograft loss. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 9 (5) , 1063-71More Information

Everly, M J; Everly, J J; Susskind, B; Brailey, P; Arend, L J; Alloway, R R; Roy-Chaudhury, P; Govil, A; Mogilishetty, G; Rike, A H; Cardi, M; Wadih, G; Brown, E; Tevar, A; Woodle, E SProteasome inhibition reduces donor-specific antibody levels. Transplantation proceedings, 41 (1) , 105-7More Information

Everly, Matthew J; Everly, Jason J; Susskind, Brian; Brailey, Paul; Arend, Lois J; Alloway, Rita R; Roy-Chaudhury, Prabir; Govil, Amit; Mogilishetty, Gautham; Rike, Adele H; Cardi, Michael; Wadih, George; Tevar, Amit; Woodle, E Steve  (2008). Bortezomib provides effective therapy for antibody- and cell-mediated acute rejection. Transplantation, 86 (12) , 1754-61More Information

Rike, Adele H; Mogilishetty, Gautham; Alloway, Rita R; Succop, Paul; Roy-Chaudhury, Prabir; Cardi, Michael; Kaiser, Tiffany E; Thomas, Mark; Woodle, E SteveCardiovascular risk, cardiovascular events, and metabolic syndrome in renal transplantation: comparison of early steroid withdrawal and chronic steroids. Clinical transplantation, 22 (2) , 229-35More Information

Woodle, E Steve; Alloway, Rita; Rike, Adele; Roy-Chaudhury, Prabir; Tevar, Amit; Susskind, Brian; Everly, Jason; Mogilishetty, Gautham; Brailey, Paul; Govil, Amit; Rudich, Steve; First, M Roy; Alexander, J Wesley; Munda, Rino; Cardi, Michael; Arend, Lois  (2007). Corticosteroid elimination: the Cincinnati experience. Clinical transplants, 51-60

Woodle, E Steve; Goldfarb, David; Aeder, Mark; Lal, Tanmay; Rike, Adele; Weimert, Nicole; Waterman, Amy  (2005). Establishment of a nationalized, multiregional Paired Donation Network. Clinical transplants, 247-58

Walker, Jennifer K; Alloway, Rita R; Roy-Chaudhury, Prabir; Mogilishetty, Gautham; Cardi, Michael A; Weimert, Nicole A; Rike, Adele H; First, M Roy; Woodle, E Steve  (2009). A prospective trial of a steroid-free/calcineurin inhibitor minimization regimen in human leukocyte antigen (HLA)-identical live donor renal transplantation. Transplantation, 87 (3) , 408-14More Information

Kim, Y; Jung, A D; Dhar, V K; Tadros, J S; Schauer, D P; Smith, E P; Hanseman, D J; Cuffy, M C; Alloway, R R; Shields, A R; Shah, S A; Woodle, E S; Diwan, T S  (2018). Laparoscopic sleeve gastrectomy improves renal transplant candidacy and posttransplant outcomes in morbidly obese patients. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 18 (2) , 410-416More Information

Diwan, Tayyab S; Lichvar, Alicia B; Leino, Abbie D; Vinks, Alexander A; Christians, Uwe; Shields, Adele R; Cardi, Michael A; Fukuda, Tsuyoshi; Mizuno, Tomoyuki; Kaiser, Tiffany; Woodle, E Steve; Alloway, Rita R  (2017). Pharmacokinetic and pharmacogenetic analysis of immunosuppressive agents after laparoscopic sleeve gastrectomy. Clinical transplantation, 31 (6) More Information

Abu Jawdeh, Bassam G; Leonard, Anthony C; Sharma, Yuvraj; Katipally, Swapna; Shields, Adele R; Alloway, Rita R; Woodle, E Steve; Thakar, Charuhas V  (2017). Contrast-Induced Nephropathy in Renal Transplant Recipients: A Single Center Experience. Frontiers in medicine, 4, 64More Information

Sadaka, Basma; Ejaz, Nicole S; Shields, Adele R; Cardi, Michael A; Wadih, George; Witte, David; Abu Jawdeh, Bassam G; Alloway, Rita R; Woodle, E Steve  (2015). A Banff Component Scoring-based Histologic Assessment of Bortezomib-based Antibody-mediated Rejection Therapy. Transplantation, 99 (8) , 1691-9More Information

Woodle, E S; Shields, A R; Ejaz, N S; Sadaka, B; Girnita, A; Walsh, R C; Alloway, R R; Brailey, P; Cardi, M A; Abu Jawdeh, B G; Roy-Chaudhury, P; Govil, A; Mogilishetty, G  (2015). Prospective iterative trial of proteasome inhibitor-based desensitization. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 15 (1) , 101-18More Information

Abu Jawdeh, Bassam G; Cuffy, Madison C; Alloway, Rita R; Shields, Adele Rike; Woodle, E Steve  (2014). Desensitization in kidney transplantation: review and future perspectives. Clinical transplantation, 28 (4) , 494-507More Information

Krisl, Jill C; Alloway, Rita R; Shields, Adele Rike; Cardi, Michael A; Woodle, E Steve  (2014). Bortezomib-based antibody-mediated rejection therapy and simultaneous conversion to belatacept. Transplantation, 97 (4) , e30-2More Information

Ejaz, N S; Shields, A R; Alloway, R R; Sadaka, B; Girnita, A L; Mogilishetty, G; Cardi, M; Woodle, E S  (2013). Randomized controlled pilot study of B cell-targeted induction therapy in HLA sensitized kidney transplant recipients. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 13 (12) , 3142-54More Information

Schmidt, Nicole; Alloway, Rita R; Walsh, R Carlin; Sadaka, Basma; Shields, Adele R; Girnita, Alin L; Hanseman, Dennis J; Woodle, E Steve  (2012). Prospective evaluation of the toxicity profile of proteasome inhibitor-based therapy in renal transplant candidates and recipients. Transplantation, 94 (4) , 352-61More Information

Sadaka, Basma; Alloway, Rita R; Shields, Adele R; Schmidt, Nicole M; Woodle, E Steve  (2012). Proteasome inhibition for antibody-mediated allograft rejection. Seminars in hematology, 49 (3) , 263-9More Information

Walsh, R Carlin; Brailey, Paul; Girnita, Alin; Alloway, Rita R; Shields, Adele Rike; Wall, Garth E; Sadaka, Basma H; Cardi, Michael; Tevar, Amit; Govil, Amit; Mogilishetty, Gautham; Roy-Chaudhury, Prabir; Woodle, E Steve  (2011). Early and late acute antibody-mediated rejection differ immunologically and in response to proteasome inhibition. Transplantation, 91 (11) , 1218-26More Information

Macedo C.;Hadi K.;Walters J.;Elinoff B.;Marrari M.;Zeevi A.;Ramaswami B.;Chalasani G.;Landsittel D.;Shields A.;Alloway R.;Lakkis F.G.;Woodle E.S.;Metes D.  (03-01-2019). Impact of Induction Therapy on Circulating T Follicular Helper Cells and Subsequent Donor-Specific A. Kidney International Reports, 4 (3) , 455-469More Information

Woodle E.S.;Kaufman D.B.;Shields A.R.;Leone J.;Matas A.;Wiseman A.;West-Thielke P.;Sa T.;King E.C.;Alloway R.R.;Brailey P.;Bruno K.;Cicerchi J.;Cline A.;Dorst T.;Farnsworth M.;Fernandez D.A.;Girnita A.;Lipscombe J.;Naciff-Stahl A.;Rohan J.;Schneider K.;Stucke A.;Thomas J.;Tremblay S.  (01-01-2019). Belatacept-based immunosuppression with simultaneous calcineurin inhibitor avoidance and early corti. American Journal of TransplantationMore Information

Jawdeh B.;Leonard A.;Sharma Y.;Katipally S.;Shields A.;Alloway R.;Steve Woodle E.;Thakar C.  (01-01-2017). Contrast-induced nephropathy in renal transplant recipients: A single center experience. Frontiers in Medicine, 4 (MAY) More Information

Castro-Rojas, Cyd M; Godarova, Alzbeta; Shi, Tiffany; Hummel, Sarah A; Shields, Adele; Tremblay, Simon; Alloway, Rita R; Jordan, Michael B; Woodle, E Steve; Hildeman, David A  (2020). mTOR Inhibitor Therapy Diminishes Circulating CD8+ CD28- Effector Memory T Cells and Improves Allograft Inflammation in Belatacept-refractory Renal Allograft Rejection. Transplantation, 104 (5) , 1058-1069More Information

Lichvar, Alicia B; Tremblay, Simon; Leino, Abbie D; Shields, Adele R; Cardi, Michael A; Abu Jawdeh, Bassam G; Govil, Amit; Kremer, Joseph; Cuffy, Madison; Paterno, Flavio; Diwan, Tayyab; Brailey, Paul; Girnita, Alin; Alloway, Rita R; Woodle, E Steve  (2020). Reducing Donor Specific Antibody During Acute Rejection Diminishes Long Term Renal Allograft Loss: Comparison of Early and Late Rejection. TransplantationMore Information

Macedo, Camila; Hadi, Kevin; Walters, John; Elinoff, Beth; Marrari, Marilyn; Zeevi, Adriana; Ramaswami, Bala; Chalasani, Geetha; Landsittel, Douglas; Shields, Adele; Alloway, Rita; Lakkis, Fadi G; Woodle, E Steve; Metes, Diana  (2019). Impact of Induction Therapy on Circulating T Follicular Helper Cells and Subsequent Donor-Specific Antibody Formation After Kidney Transplant. Kidney international reports, 4 (3) , 455-469More Information

Woodle, E Steve; Kaufman, Dixon B; Shields, Adele R; Leone, John; Matas, Arthur; Wiseman, Alexander; West-Thielke, Patricia; Sa, Ting; King, Eileen C; Alloway, Rita R  (2020). Belatacept-based immunosuppression with simultaneous calcineurin inhibitor avoidance and early corticosteroid withdrawal: A prospective, randomized multicenter trial. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 20 (4) , 1039-1055More Information

Kaufman, Dixon B; Woodle, E Steve; Shields, Adele Rike; Leone, John; Matas, Arthur; Wiseman, Alexander; West-Thielke, Patricia; Sa, Ting; King, Eileen C; Alloway, Rita R  (2021). Belatacept for Simultaneous Calcineurin Inhibitor and Chronic Corticosteroid Immunosuppression Avoidance: Two-Year Results of a Prospective, Randomized Multicenter Trial. Clinical journal of the American Society of Nephrology : CJASN, 16 (9) , 1387-1397More Information

Shi, Tiffany; Burg, Ashley R; Caldwell, J Timothy; Roskin, Krishna M; Castro-Rojas, Cyd M; Chukwuma, P Chukwunalu; Gray, George I; Foote, Sara G; Alonso, Jesus A; Cuda, Carla M; Allman, David A; Rush, James S; Regnier, Catherine H; Wieczorek, Grazyna; Alloway, Rita R; Shields, Adele R; Baker, Brian M; Woodle, E Steve; Hildeman, David A  (2023). Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality. The Journal of clinical investigation, 133 (14) More Information

Shi, Tiffany; Burg, Ashley R; Caldwell, J Timothy; Roskin, Krishna; Castro-Rojas, Cyd M; Chukwuma, P Chukwunalu; Gray, George I; Foote, Sara G; Alonso, Jesus; Cuda, Carla M; Allman, David A; Rush, James S; Regnier, Catherine H; Wieczorek, Grazyna; Alloway, Rita R; Shields, Adele R; Baker, Brian M; Woodle, E Steve; Hildeman, David A  (2023). Single cell transcriptomic analysis of renal allograft rejection reveals novel insights into intragraft TCR clonality. bioRxiv : the preprint server for biologyMore Information

Wilson, Nicole K; Tremblay, Simon; Shields, Adele R; Woodle, E Steve; Alloway, Rita R; Vinks, Alexander A; Miyagawa, Bradley; Mizuno, Tomoyuki  (2024). Belatacept Removal by Plasmapheresis: Dose Adjustments and Clinical Recommendations. Transplantation direct, 10 (8) , e1677More Information

Pyatt A.; McGowan M.; Tanaka R.; Miyagawa B.; Mizuno T.; Shields A.R.; Christianson A.; West-Thielke P.; Leone J.P.; Woodle E.S.; Kaufman D.; Wiseman A.; Matas A.J.; Vinks A.A.; Alloway R.R.  (08-01-2025). Belatacept Pharmacokinetic Analysis of Belatacept Early Steroid Withdrawal Trial (BEST) to Clinical . Clinical Transplantation, 39 (8) More Information

Wilson N.K.; Tremblay S.; Shields A.R.; Woodle E.S.; Alloway R.R.; Vinks A.A.; Miyagawa B.; Mizuno T.  (07-05-2024). Belatacept Removal by Plasmapheresis: Dose Adjustments and Clinical Recommendations. Transplantation Direct, 10 (8) , e1677More Information

Academic - Christ Hospital Medical Office Building
Room 308
Cincinnati  Ohio, 45219
Phone: 513-585-2145
adele.rike@uc.edu